ZA200408826B - Method for the microbial production of aromatic amino acids and other metabolites of the aromatic amino acid biosynthetic pathway - Google Patents
Method for the microbial production of aromatic amino acids and other metabolites of the aromatic amino acid biosynthetic pathway Download PDFInfo
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- ZA200408826B ZA200408826B ZA200408826A ZA200408826A ZA200408826B ZA 200408826 B ZA200408826 B ZA 200408826B ZA 200408826 A ZA200408826 A ZA 200408826A ZA 200408826 A ZA200408826 A ZA 200408826A ZA 200408826 B ZA200408826 B ZA 200408826B
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- South Africa
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- microorganism
- aromatic amino
- gene sequence
- pyc gene
- pyc
- Prior art date
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- C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
- C12P13/00—Preparation of nitrogen-containing organic compounds
- C12P13/04—Alpha- or beta- amino acids
- C12P13/22—Tryptophan; Tyrosine; Phenylalanine; 3,4-Dihydroxyphenylalanine
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Y—ENZYMES
- C12Y604/00—Ligases forming carbon-carbon bonds (6.4)
- C12Y604/01—Ligases forming carbon-carbon bonds (6.4.1)
- C12Y604/01001—Pyruvate carboxylase (6.4.1.1)
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- Organic Chemistry (AREA)
- Chemical & Material Sciences (AREA)
- Engineering & Computer Science (AREA)
- Life Sciences & Earth Sciences (AREA)
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- Chemical Kinetics & Catalysis (AREA)
- Biotechnology (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
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DE10219714A DE10219714A1 (de) | 2002-05-02 | 2002-05-02 | Verfahren zur mikrobielien Herstellung von aromatischen Aminosäuren und anderen Metaboliten des aromatischen Aminosäurebiosyntheseweges |
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DE (1) | DE10219714A1 (fr) |
WO (1) | WO2003093490A1 (fr) |
ZA (1) | ZA200408826B (fr) |
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WO2006042666A1 (fr) * | 2004-10-18 | 2006-04-27 | Meda Pharma Gmbh & Co. Kg | Utilisation d'acide alpha-lipoique r-(+) pour prevenir le diabete |
EP1907529A1 (fr) * | 2005-07-25 | 2008-04-09 | Ajinomoto Co., Inc. | MÉTHODE POUR PRODUIRE UN ACIDE L-AMINÉ QUI UTILISE UNE BACTÉRIE DE LA FAMILLE DES ENTEROBACTERIACAE AVEC UNE EXPRESSION ATTÉNUÉE DU GÈNE cpxR |
RU2006129690A (ru) | 2006-08-16 | 2008-02-27 | Закрытое акционерное общество "Научно-исследовательский институт Аджиномото-Генетика" (ЗАО АГРИ) (RU) | СПОСОБ ПОЛУЧЕНИЯ L-АМИНОКИСЛОТЫ С ИСПОЛЬЗОВАНИЕМ БАКТЕРИЙ СЕМЕЙСТВА Enterobacteriaceae, В КОТОРОЙ ОСЛАБЛЕНА ЭКСПРЕССИЯ ГЕНА ydiN, ГЕНА ydiB ИЛИ ИХ КОМБИНАЦИИ |
KR100850853B1 (ko) * | 2006-12-13 | 2008-08-06 | 씨제이제일제당 (주) | nrfE 유전자가 불활성화된 L-트립토판 생산 미생물 및이를 이용한 L-트립토판 제조방법 |
US8647642B2 (en) | 2008-09-18 | 2014-02-11 | Aviex Technologies, Llc | Live bacterial vaccines resistant to carbon dioxide (CO2), acidic PH and/or osmolarity for viral infection prophylaxis or treatment |
WO2010077806A1 (fr) * | 2008-12-15 | 2010-07-08 | Greenlight Biosciences, Inc. | Procédés de commande de flux dans des voies métaboliques |
KR20130071433A (ko) | 2010-05-07 | 2013-06-28 | 그린라이트 바이오사이언시스, 아이엔씨. | 효소의 재배치를 통한 대사 경로에서의 흐름의 제어 방법 |
JP6280367B2 (ja) | 2010-08-31 | 2018-02-14 | グリーンライト バイオサイエンシーズ インコーポレーテッドGreenlight Biosciences,Inc. | プロテアーゼ操作を介した代謝経路におけるフラックスの制御のための方法 |
CA2846893A1 (fr) | 2011-09-09 | 2013-03-14 | Greenlight Biosciences, Inc. | Preparation de carbapenemes effectuee sans cellules |
JP2016504034A (ja) | 2012-12-21 | 2016-02-12 | グリーンライト バイオサイエンシーズ インコーポレーテッドGreenlight Biosciences,Inc. | メタンを燃料、ピルビン酸またはイソブタノールに変換する無細胞システム |
BR112016002494A2 (pt) | 2013-08-05 | 2017-09-05 | Greenlight Biosciences Inc | Proteí-nas construídas com um sítio de clivagem de protease, ácido nucléico, vetor, célula e processo de engenharia de uma proteína recombinante e de um grande número de variantes de ácidos nucleicos que codificam proteínas recombinantes |
MX2017012665A (es) | 2015-03-30 | 2018-04-24 | Greenlight Biosciences Inc | Produccion de acido ribonucleico libre de celulas. |
EP4293104A3 (fr) | 2016-04-06 | 2024-04-24 | Greenlight Biosciences, Inc. | Production acellulaire d'acide ribonucléique |
US11129906B1 (en) | 2016-12-07 | 2021-09-28 | David Gordon Bermudes | Chimeric protein toxins for expression by therapeutic bacteria |
US11180535B1 (en) | 2016-12-07 | 2021-11-23 | David Gordon Bermudes | Saccharide binding, tumor penetration, and cytotoxic antitumor chimeric peptides from therapeutic bacteria |
KR20190100386A (ko) | 2017-01-06 | 2019-08-28 | 그린라이트 바이오사이언시스, 아이엔씨. | 당의 무세포 생산 |
KR20230130144A (ko) | 2017-10-11 | 2023-09-11 | 그린라이트 바이오사이언시스, 아이엔씨. | 뉴클레오시드 트리포스페이트 및 리보핵산 생산을 위한 방법 및 조성물 |
CN112251476B (zh) * | 2020-09-25 | 2022-11-15 | 天津科技大学 | 一种l-苯丙氨酸的生产方法 |
CN115806926A (zh) * | 2022-11-11 | 2023-03-17 | 天津科技大学 | 一种生产假尿苷的基因工程菌株及其构建方法与应用 |
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DE19644566A1 (de) * | 1996-10-26 | 1998-04-30 | Forschungszentrum Juelich Gmbh | Mikrobielle Herstellung von Substanzen aus dem aromatischen Stoffwechsel / I |
DE19831609B4 (de) * | 1997-10-04 | 2009-11-12 | Evonik Degussa Gmbh | Verfahren zur Herstellung von Aminosäuren der Aspartat- und/oder Glutamatfamilie und im Verfahren einsetzbare Mittel |
US6171833B1 (en) * | 1998-12-23 | 2001-01-09 | Massachusetts Institute Of Technology | Pyruvate carboxylase from corynebacterium glutamicum |
US6797509B1 (en) * | 1999-07-09 | 2004-09-28 | Degussa-Huls Ag | Nucleotide sequences which code for the tal gene |
AR026892A1 (es) * | 1999-10-13 | 2003-03-05 | Univ Georgia Res Found | Sistema y metodos de expresion de proteina de alto rendimiento |
DE10047866A1 (de) * | 2000-09-27 | 2002-04-11 | Degussa | Neue für das dep67-Gen kodierende Nukleotidsequenzen |
DE10063314A1 (de) * | 2000-12-20 | 2002-07-04 | Degussa | Neue für das ilvE-Gen kodierende Nukleotidsequenzen |
-
2002
- 2002-05-02 DE DE10219714A patent/DE10219714A1/de not_active Ceased
-
2003
- 2003-04-29 WO PCT/DE2003/001380 patent/WO2003093490A1/fr not_active Application Discontinuation
- 2003-04-29 US US10/513,424 patent/US20060234358A1/en not_active Abandoned
- 2003-04-29 CA CA002484379A patent/CA2484379A1/fr not_active Abandoned
- 2003-04-29 EP EP03732215A patent/EP1499737A1/fr not_active Withdrawn
- 2003-04-29 AU AU2003238347A patent/AU2003238347A1/en not_active Abandoned
-
2004
- 2004-11-01 ZA ZA200408826A patent/ZA200408826B/en unknown
Also Published As
Publication number | Publication date |
---|---|
DE10219714A1 (de) | 2003-11-27 |
EP1499737A1 (fr) | 2005-01-26 |
WO2003093490A1 (fr) | 2003-11-13 |
AU2003238347A8 (en) | 2003-11-17 |
AU2003238347A1 (en) | 2003-11-17 |
US20060234358A1 (en) | 2006-10-19 |
CA2484379A1 (fr) | 2003-11-13 |
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