ZA200403781B - Solid pharmaceutical formulation for a piperazine urea derivative. - Google Patents
Solid pharmaceutical formulation for a piperazine urea derivative. Download PDFInfo
- Publication number
- ZA200403781B ZA200403781B ZA200403781A ZA200403781A ZA200403781B ZA 200403781 B ZA200403781 B ZA 200403781B ZA 200403781 A ZA200403781 A ZA 200403781A ZA 200403781 A ZA200403781 A ZA 200403781A ZA 200403781 B ZA200403781 B ZA 200403781B
- Authority
- ZA
- South Africa
- Prior art keywords
- methyl
- pharmaceutical agent
- piperazine
- formulation according
- agent formulation
- Prior art date
Links
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- 239000008194 pharmaceutical composition Substances 0.000 title claims 2
- QHTPSODXPLCXJB-UHFFFAOYSA-N piperazine;urea Chemical class NC(N)=O.C1CNCCN1 QHTPSODXPLCXJB-UHFFFAOYSA-N 0.000 title description 11
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- 238000009472 formulation Methods 0.000 claims description 63
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Classifications
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
- A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
- A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
- A61K9/1605—Excipients; Inactive ingredients
- A61K9/1629—Organic macromolecular compounds
- A61K9/1652—Polysaccharides, e.g. alginate, cellulose derivatives; Cyclodextrin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/2004—Excipients; Inactive ingredients
- A61K9/2013—Organic compounds, e.g. phospholipids, fats
- A61K9/2018—Sugars, or sugar alcohols, e.g. lactose, mannitol; Derivatives thereof, e.g. polysorbates
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/2004—Excipients; Inactive ingredients
- A61K9/2022—Organic macromolecular compounds
- A61K9/2027—Organic macromolecular compounds obtained by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyvinyl pyrrolidone, poly(meth)acrylates
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A61P17/06—Antipsoriatics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
- A61P19/02—Drugs for skeletal disorders for joint disorders, e.g. arthritis, arthrosis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/08—Antiallergic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
- A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
- A61K9/1605—Excipients; Inactive ingredients
- A61K9/1629—Organic macromolecular compounds
- A61K9/1635—Organic macromolecular compounds obtained by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyvinyl pyrrolidone, poly(meth)acrylates
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/2004—Excipients; Inactive ingredients
- A61K9/2022—Organic macromolecular compounds
- A61K9/205—Polysaccharides, e.g. alginate, gums; Cyclodextrin
- A61K9/2054—Cellulose; Cellulose derivatives, e.g. hydroxypropyl methylcellulose
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Veterinary Medicine (AREA)
- Pharmacology & Pharmacy (AREA)
- Public Health (AREA)
- Chemical & Material Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Animal Behavior & Ethology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Organic Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Epidemiology (AREA)
- Immunology (AREA)
- Rheumatology (AREA)
- Dermatology (AREA)
- Neurology (AREA)
- Neurosurgery (AREA)
- Pain & Pain Management (AREA)
- Biomedical Technology (AREA)
- Heart & Thoracic Surgery (AREA)
- Orthopedic Medicine & Surgery (AREA)
- Physical Education & Sports Medicine (AREA)
- Cardiology (AREA)
- Biophysics (AREA)
- Molecular Biology (AREA)
- Pulmonology (AREA)
- Medicinal Preparation (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| DE10152351A DE10152351B4 (de) | 2001-10-18 | 2001-10-18 | Feste Arzneimittelformulierung für ein Piperazinharnstoffderivat |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ZA200403781B true ZA200403781B (en) | 2004-11-29 |
Family
ID=7703496
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ZA200403781A ZA200403781B (en) | 2001-10-18 | 2004-05-17 | Solid pharmaceutical formulation for a piperazine urea derivative. |
Country Status (23)
| Country | Link |
|---|---|
| EP (1) | EP1435917A1 (es) |
| JP (1) | JP2005506365A (es) |
| KR (1) | KR20040047920A (es) |
| CN (1) | CN1571660A (es) |
| AR (1) | AR037111A1 (es) |
| AU (1) | AU2002333896B2 (es) |
| BR (1) | BR0213340A (es) |
| CA (1) | CA2463951A1 (es) |
| CO (1) | CO5580740A2 (es) |
| DE (1) | DE10152351B4 (es) |
| EC (1) | ECSP045108A (es) |
| HR (1) | HRP20040435A2 (es) |
| IL (1) | IL161166A0 (es) |
| MX (1) | MXPA04003522A (es) |
| NO (1) | NO20042022L (es) |
| NZ (1) | NZ532287A (es) |
| PE (1) | PE20030472A1 (es) |
| PL (1) | PL367987A1 (es) |
| RS (1) | RS32204A (es) |
| RU (1) | RU2311172C2 (es) |
| UY (1) | UY27500A1 (es) |
| WO (1) | WO2003035037A1 (es) |
| ZA (1) | ZA200403781B (es) |
Families Citing this family (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| ATE374181T1 (de) | 2001-06-27 | 2007-10-15 | Smithkline Beecham Corp | Fluorpyrrolidine als dipeptidylpeptidaseinhibitoren |
| EP1749519A1 (de) * | 2005-08-05 | 2007-02-07 | Schering Aktiengesellschaft | Arzneiform mit Retardtierter pH-unabhängiger Wirkstofffreisetzung für Wirkstoffe mit starker pH-abhängiger Löslichkeit |
| EP2010158B1 (en) * | 2006-04-26 | 2016-02-17 | Alphapharm Pty Ltd. | Controlled release formulations comprising uncoated discrete unit(s) and an extended release matrix |
| DE102008047910A1 (de) | 2008-09-19 | 2010-03-25 | Molkerei Meggle Wasserburg Gmbh & Co. Kg | Tablettierhilfsstoff auf Laktose- und Cellulosebasis |
| KR101654582B1 (ko) | 2016-05-12 | 2016-09-06 | 그린로드(주) | 원뿔형 부유 고분자 필터, 및 그의 제조장치 및 제조방법, 및 그를 포함하는 수처리 필터 |
| RU2729223C1 (ru) * | 2020-05-13 | 2020-08-05 | Мераб Георгиевич Чикобава | Дозированная форма для амплификации нуклеиновых кислот |
Family Cites Families (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US6207665B1 (en) * | 1997-06-12 | 2001-03-27 | Schering Aktiengesellschaft | Piperazine derivatives and their use as anti-inflammatory agents |
| EA003137B1 (ru) * | 1998-02-05 | 2003-02-27 | Пфайзер Продактс Инк | Новые производные дигидроксигексановой кислоты |
| EP1027885B1 (en) * | 1999-02-09 | 2008-07-09 | Pfizer Products Inc. | Basic drug compositions with enhanced bioavailability |
-
2001
- 2001-10-18 DE DE10152351A patent/DE10152351B4/de not_active Expired - Fee Related
-
2002
- 2002-10-07 BR BR0213340-7A patent/BR0213340A/pt not_active IP Right Cessation
- 2002-10-07 PL PL02367987A patent/PL367987A1/xx not_active Application Discontinuation
- 2002-10-07 CN CNA02820512XA patent/CN1571660A/zh active Pending
- 2002-10-07 RU RU2004115328/15A patent/RU2311172C2/ru not_active IP Right Cessation
- 2002-10-07 EP EP02801884A patent/EP1435917A1/de not_active Withdrawn
- 2002-10-07 MX MXPA04003522A patent/MXPA04003522A/es unknown
- 2002-10-07 IL IL16116602A patent/IL161166A0/xx unknown
- 2002-10-07 AU AU2002333896A patent/AU2002333896B2/en not_active Ceased
- 2002-10-07 NZ NZ532287A patent/NZ532287A/en unknown
- 2002-10-07 CA CA002463951A patent/CA2463951A1/en not_active Abandoned
- 2002-10-07 KR KR10-2004-7005591A patent/KR20040047920A/ko not_active Application Discontinuation
- 2002-10-07 RS YU32204A patent/RS32204A/sr unknown
- 2002-10-07 WO PCT/EP2002/011229 patent/WO2003035037A1/de not_active Application Discontinuation
- 2002-10-07 JP JP2003537604A patent/JP2005506365A/ja active Pending
- 2002-10-17 PE PE2002001027A patent/PE20030472A1/es not_active Application Discontinuation
- 2002-10-17 UY UY27500A patent/UY27500A1/es not_active Application Discontinuation
- 2002-10-18 AR ARP020103929A patent/AR037111A1/es unknown
-
2004
- 2004-05-13 CO CO04044345A patent/CO5580740A2/es not_active Application Discontinuation
- 2004-05-14 NO NO20042022A patent/NO20042022L/no not_active Application Discontinuation
- 2004-05-17 EC EC2004005108A patent/ECSP045108A/es unknown
- 2004-05-17 HR HR20040435A patent/HRP20040435A2/hr not_active Application Discontinuation
- 2004-05-17 ZA ZA200403781A patent/ZA200403781B/en unknown
Also Published As
| Publication number | Publication date |
|---|---|
| WO2003035037A1 (de) | 2003-05-01 |
| AR037111A1 (es) | 2004-10-20 |
| CO5580740A2 (es) | 2005-11-30 |
| EP1435917A1 (de) | 2004-07-14 |
| DE10152351A1 (de) | 2003-05-08 |
| RS32204A (en) | 2006-10-27 |
| PE20030472A1 (es) | 2003-06-16 |
| KR20040047920A (ko) | 2004-06-05 |
| RU2004115328A (ru) | 2005-06-10 |
| BR0213340A (pt) | 2004-10-05 |
| UY27500A1 (es) | 2003-06-30 |
| DE10152351B4 (de) | 2005-09-22 |
| AU2002333896A2 (en) | 2003-05-06 |
| PL367987A1 (en) | 2005-03-21 |
| NZ532287A (en) | 2007-04-27 |
| RU2311172C2 (ru) | 2007-11-27 |
| HRP20040435A2 (en) | 2005-06-30 |
| AU2002333896B2 (en) | 2007-07-26 |
| MXPA04003522A (es) | 2004-07-23 |
| NO20042022L (no) | 2004-05-14 |
| CA2463951A1 (en) | 2003-05-01 |
| JP2005506365A (ja) | 2005-03-03 |
| ECSP045108A (es) | 2004-06-28 |
| IL161166A0 (en) | 2004-08-31 |
| CN1571660A (zh) | 2005-01-26 |
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