ZA200402899B - Supercritical fluids processing: Preparation of protein microparticles and their stabilisation. - Google Patents

Supercritical fluids processing: Preparation of protein microparticles and their stabilisation. Download PDF

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Publication number
ZA200402899B
ZA200402899B ZA200402899A ZA200402899A ZA200402899B ZA 200402899 B ZA200402899 B ZA 200402899B ZA 200402899 A ZA200402899 A ZA 200402899A ZA 200402899 A ZA200402899 A ZA 200402899A ZA 200402899 B ZA200402899 B ZA 200402899B
Authority
ZA
South Africa
Prior art keywords
supercritical fluid
solution
modifier
solvent
process according
Prior art date
Application number
ZA200402899A
Other languages
English (en)
Inventor
Marco Gentile
Cesare Di Palma
Maria Candida Cesta
Original Assignee
Dompe Spa
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Dompe Spa filed Critical Dompe Spa
Publication of ZA200402899B publication Critical patent/ZA200402899B/en

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Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K1/00General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length
    • C07K1/14Extraction; Separation; Purification
    • C07K1/30Extraction; Separation; Purification by precipitation
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K1/00General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length
    • C07K1/02General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length in solution
    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02PCLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
    • Y02P20/00Technologies relating to chemical industry
    • Y02P20/50Improvements relating to the production of bulk chemicals
    • Y02P20/54Improvements relating to the production of bulk chemicals using solvents, e.g. supercritical solvents or ionic liquids

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Analytical Chemistry (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Medicinal Chemistry (AREA)
  • Molecular Biology (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Preparation (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)
  • Colloid Chemistry (AREA)
  • Enzymes And Modification Thereof (AREA)
  • Medical Preparation Storing Or Oral Administration Devices (AREA)
  • Extraction Or Liquid Replacement (AREA)
  • Physical Or Chemical Processes And Apparatus (AREA)
ZA200402899A 2001-10-22 2004-04-16 Supercritical fluids processing: Preparation of protein microparticles and their stabilisation. ZA200402899B (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
EP01125048 2001-10-22

Publications (1)

Publication Number Publication Date
ZA200402899B true ZA200402899B (en) 2005-04-18

Family

ID=8179030

Family Applications (1)

Application Number Title Priority Date Filing Date
ZA200402899A ZA200402899B (en) 2001-10-22 2004-04-16 Supercritical fluids processing: Preparation of protein microparticles and their stabilisation.

Country Status (21)

Country Link
US (2) US7250152B2 (pt)
EP (1) EP1440082B1 (pt)
JP (1) JP4374249B2 (pt)
KR (1) KR100887429B1 (pt)
CN (1) CN1575298A (pt)
AT (1) ATE526340T1 (pt)
AU (1) AU2002350588B2 (pt)
BR (1) BR0213430A (pt)
CA (1) CA2464308A1 (pt)
DK (1) DK1440082T3 (pt)
ES (1) ES2372032T3 (pt)
HU (1) HUP0402096A3 (pt)
IL (2) IL161447A0 (pt)
MX (1) MXPA04003718A (pt)
NO (1) NO330504B1 (pt)
NZ (1) NZ532395A (pt)
PL (1) PL209826B1 (pt)
PT (1) PT1440082E (pt)
RU (1) RU2309160C2 (pt)
WO (1) WO2003035673A1 (pt)
ZA (1) ZA200402899B (pt)

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US6541606B2 (en) * 1997-12-31 2003-04-01 Altus Biologics Inc. Stabilized protein crystals formulations containing them and methods of making them
MXPA04003718A (es) * 2001-10-22 2004-07-30 Dompe Spa Procesamiento de fluidos supercriticos: preparacion de microparticulas de proteina y su estabilizacion.
GB0300338D0 (en) * 2003-01-08 2003-02-05 Bradford Particle Design Ltd Particle formation
US7223445B2 (en) * 2004-03-31 2007-05-29 Eastman Kodak Company Process for the deposition of uniform layer of particulate material
DE102004049850A1 (de) * 2004-09-15 2006-03-02 Cognis Ip Management Gmbh Verfahren und Anlage zur Herstellung von Mikropartikeln oder Nanopartikeln, Verwendung der Nanopartikel und damit hergestellte Suspension oder Emulsion
CN1302766C (zh) * 2005-06-23 2007-03-07 同济大学 超临界抗溶剂过程制备可生物降解聚合物载药微粒的方法
KR100705282B1 (ko) * 2005-06-30 2007-04-12 주식회사 케이씨아이 유채씨로부터 분리 단백질을 제조하는 방법
WO2008134464A2 (en) * 2007-04-25 2008-11-06 3M Innovative Properties Company Sample-processing reagent compositions, methods, and devices
ATE539165T1 (de) 2007-10-19 2012-01-15 Becton Dickinson Co Verfahren zum nachweis von beta-lactamase
WO2010047778A1 (en) 2008-10-20 2010-04-29 Becton Dickinson And Company Compositions for the detection of intracellular bacterial targets and other intracellular microorganism targets
US9138705B2 (en) 2010-11-22 2015-09-22 Hong Kong Polytechnic University Method for precipitating a solute from a solution
US9149045B2 (en) 2010-12-07 2015-10-06 Kimberly-Clark Worldwide, Inc. Wipe coated with a botanical emulsion having antimicrobial properties
US9648874B2 (en) 2010-12-07 2017-05-16 Kimberly-Clark Worldwide, Inc. Natural, multiple use and re-use, user saturated wipes
US9832993B2 (en) 2010-12-07 2017-12-05 Kimberly-Clark Worldwide, Inc. Melt processed antimicrobial composition
US10821085B2 (en) 2010-12-07 2020-11-03 Kimberly-Clark Worldwide, Inc. Wipe coated with a botanical composition having antimicrobial properties
US8524264B2 (en) 2010-12-07 2013-09-03 Kimberly-Clark Worldwide, Inc. Protein stabilized antimicrobial composition formed by melt processing
US8445032B2 (en) 2010-12-07 2013-05-21 Kimberly-Clark Worldwide, Inc. Melt-blended protein composition
US8574628B2 (en) 2011-12-19 2013-11-05 Kimberly-Clark Worldwide, Inc. Natural, multiple release and re-use compositions
US9925512B2 (en) 2013-03-14 2018-03-27 Crititech, Inc. Equipment assembly for and method of processing particles
US8778181B1 (en) 2013-03-14 2014-07-15 Crititech, Inc. Equipment assembly for and method of processing particles
US20160244547A1 (en) * 2013-10-10 2016-08-25 New York University Efficient collection of nanoparticles
EP3236720A4 (en) * 2014-11-28 2018-10-10 Zeon Corporation Desmear processing method and manufacturing method for multilayer printed wiring board
CN105727579B (zh) * 2016-01-28 2018-01-09 苏州鼎烯聚材纳米科技有限公司 浆料的低成本高效率超临界喷雾干燥方法及设备
US10206873B1 (en) 2017-08-04 2019-02-19 Colorado Can Llc Dry powder formation using a variably constrained, divided pathway for mixing fluid streams
CN109430514B (zh) * 2018-11-02 2022-07-26 广东海洋大学 一种制备罗非鱼-豆粕共沉淀蛋白的方法
KR102154923B1 (ko) * 2019-03-05 2020-09-10 서울대학교산학협력단 배양액의 결정화 및 초임계 건조 장치 및 방법
CN110055238A (zh) * 2019-05-13 2019-07-26 东北农业大学 一种海参花碱性磷酸酶的提取方法
CN114213382A (zh) * 2021-12-10 2022-03-22 大连理工大学 一种基于超临界抗溶剂工艺合成微纳米级别egcg的方法
CN114831930B (zh) * 2022-03-28 2023-09-05 厦门大学 一种胶原蛋白组装眼药、制备方法及应用

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DE2748132A1 (de) 1977-10-27 1979-05-03 Behringwerke Ag Stabilisator fuer polysaccharid
JPS5874696A (ja) 1981-10-30 1983-05-06 株式会社 ヤトロン アデノシン三リン酸の安定化方法
US4457916A (en) 1982-08-31 1984-07-03 Asahi Kasei Kogyo Kabushiki Kaisha Method for stabilizing Tumor Necrosis Factor and a stable aqueous solution or powder containing the same
US4891319A (en) 1985-07-09 1990-01-02 Quadrant Bioresources Limited Protection of proteins and the like
US6063910A (en) 1991-11-14 2000-05-16 The Trustees Of Princeton University Preparation of protein microparticles by supercritical fluid precipitation
US5639441A (en) 1992-03-06 1997-06-17 Board Of Regents Of University Of Colorado Methods for fine particle formation
WO1994008599A1 (en) 1992-10-14 1994-04-28 The Regents Of The University Of Colorado Ion-pairing of drugs for improved efficacy and delivery
GB9313642D0 (en) 1993-07-01 1993-08-18 Glaxo Group Ltd Method and apparatus for the formation of particles
GB9413202D0 (en) 1994-06-30 1994-08-24 Univ Bradford Method and apparatus for the formation of particles
US5874029A (en) 1996-10-09 1999-02-23 The University Of Kansas Methods for particle micronization and nanonization by recrystallization from organic solutions sprayed into a compressed antisolvent
GB9703673D0 (en) 1997-02-21 1997-04-09 Bradford Particle Design Ltd Method and apparatus for the formation of particles
GB9810559D0 (en) 1998-05-15 1998-07-15 Bradford Particle Design Ltd Method and apparatus for particle formation
GB9910975D0 (en) 1999-05-13 1999-07-14 Univ Strathclyde Rapid dehydration of proteins
US6630121B1 (en) * 1999-06-09 2003-10-07 The Regents Of The University Of Colorado Supercritical fluid-assisted nebulization and bubble drying
GB9915975D0 (en) 1999-07-07 1999-09-08 Bradford Particle Design Ltd Method for the formation of particles
GB9920558D0 (en) 1999-08-31 1999-11-03 Bradford Particle Design Ltd Methods for particle formation and their products
EP1363726B1 (en) * 2001-02-26 2004-09-01 Dompé S.P.A. Apparatus and method for micron and submicron particle formation
MXPA04003718A (es) * 2001-10-22 2004-07-30 Dompe Spa Procesamiento de fluidos supercriticos: preparacion de microparticulas de proteina y su estabilizacion.

Also Published As

Publication number Publication date
WO2003035673A9 (en) 2003-11-13
PL209826B1 (pl) 2011-10-31
IL161447A0 (en) 2004-09-27
RU2004112424A (ru) 2005-10-10
HUP0402096A2 (hu) 2005-01-28
NZ532395A (en) 2006-03-31
US20070293655A1 (en) 2007-12-20
AU2002350588A2 (en) 2003-05-06
NO20041634L (no) 2004-06-17
EP1440082B1 (en) 2011-09-28
EP1440082A1 (en) 2004-07-28
JP2005514341A (ja) 2005-05-19
RU2309160C2 (ru) 2007-10-27
AU2002350588B2 (en) 2008-08-28
NO330504B1 (no) 2011-05-02
US7250152B2 (en) 2007-07-31
US20050065063A1 (en) 2005-03-24
HUP0402096A3 (en) 2012-09-28
IL161447A (en) 2010-11-30
JP4374249B2 (ja) 2009-12-02
ATE526340T1 (de) 2011-10-15
KR100887429B1 (ko) 2009-03-09
KR20040075856A (ko) 2004-08-30
PL370303A1 (en) 2005-05-16
ES2372032T3 (es) 2012-01-13
CA2464308A1 (en) 2003-05-01
BR0213430A (pt) 2004-11-09
WO2003035673A1 (en) 2003-05-01
DK1440082T3 (da) 2012-01-16
MXPA04003718A (es) 2004-07-30
PT1440082E (pt) 2011-12-07
CN1575298A (zh) 2005-02-02

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