HUP0402096A2 - Szuperkritikus fluidumok feldolgozása: protein mikrorészecskék előállítása és stabilizálása - Google Patents
Szuperkritikus fluidumok feldolgozása: protein mikrorészecskék előállítása és stabilizálásaInfo
- Publication number
- HUP0402096A2 HUP0402096A2 HU0402096A HUP0402096A HUP0402096A2 HU P0402096 A2 HUP0402096 A2 HU P0402096A2 HU 0402096 A HU0402096 A HU 0402096A HU P0402096 A HUP0402096 A HU P0402096A HU P0402096 A2 HUP0402096 A2 HU P0402096A2
- Authority
- HU
- Hungary
- Prior art keywords
- stabilisation
- preparation
- supercritical fluids
- protein microparticles
- fluids processing
- Prior art date
Links
- 239000012530 fluid Substances 0.000 title abstract 3
- 239000011859 microparticle Substances 0.000 title 1
- 102000004169 proteins and genes Human genes 0.000 title 1
- 108090000623 proteins and genes Proteins 0.000 title 1
- 230000006641 stabilisation Effects 0.000 title 1
- 239000003381 stabilizer Substances 0.000 abstract 3
- 239000000126 substance Substances 0.000 abstract 3
- 239000002904 solvent Substances 0.000 abstract 2
- 239000012296 anti-solvent Substances 0.000 abstract 1
- 239000003607 modifier Substances 0.000 abstract 1
- 239000002245 particle Substances 0.000 abstract 1
- 230000001376 precipitating effect Effects 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K1/00—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length
- C07K1/14—Extraction; Separation; Purification
- C07K1/30—Extraction; Separation; Purification by precipitation
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K1/00—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length
- C07K1/02—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length in solution
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
- Y02P20/00—Technologies relating to chemical industry
- Y02P20/50—Improvements relating to the production of bulk chemicals
- Y02P20/54—Improvements relating to the production of bulk chemicals using solvents, e.g. supercritical solvents or ionic liquids
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Analytical Chemistry (AREA)
- Biochemistry (AREA)
- Biophysics (AREA)
- General Health & Medical Sciences (AREA)
- Genetics & Genomics (AREA)
- Medicinal Chemistry (AREA)
- Molecular Biology (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Medicinal Preparation (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Peptides Or Proteins (AREA)
- Colloid Chemistry (AREA)
- Enzymes And Modification Thereof (AREA)
- Extraction Or Liquid Replacement (AREA)
- Medical Preparation Storing Or Oral Administration Devices (AREA)
- Physical Or Chemical Processes And Apparatus (AREA)
Abstract
A találmány tárgya eljárás egy anyagnak stabilizátorral együtt történőkicsapatására gáznemű antioldószert használva, amelynek során egyrészecske kialakító edénybe szuperkritikus fluidumot vezetnek tisztánvagy módosítószerrel keverve, valamint egy olyan oldatot, amely azemlített anyagot és stabilizátort tartalmazza oldószerben oldottformában, és a szuperkritikus fluidummal kivonják az oldószert azoldatból, és együttesen kicsapatják az anyagot és a stabilizátort. Ó
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
EP01125048 | 2001-10-22 | ||
PCT/EP2002/011761 WO2003035673A1 (en) | 2001-10-22 | 2002-10-21 | Supercritical fluids processing: preparation of protein microparticles and their stabilisation |
Publications (2)
Publication Number | Publication Date |
---|---|
HUP0402096A2 true HUP0402096A2 (hu) | 2005-01-28 |
HUP0402096A3 HUP0402096A3 (en) | 2012-09-28 |
Family
ID=8179030
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
HU0402096A HUP0402096A3 (en) | 2001-10-22 | 2002-10-21 | Supercritical fluids processing: preparation of protein microparticles and their stabilisation |
Country Status (21)
Country | Link |
---|---|
US (2) | US7250152B2 (hu) |
EP (1) | EP1440082B1 (hu) |
JP (1) | JP4374249B2 (hu) |
KR (1) | KR100887429B1 (hu) |
CN (1) | CN1575298A (hu) |
AT (1) | ATE526340T1 (hu) |
AU (1) | AU2002350588B2 (hu) |
BR (1) | BR0213430A (hu) |
CA (1) | CA2464308A1 (hu) |
DK (1) | DK1440082T3 (hu) |
ES (1) | ES2372032T3 (hu) |
HU (1) | HUP0402096A3 (hu) |
IL (2) | IL161447A0 (hu) |
MX (1) | MXPA04003718A (hu) |
NO (1) | NO330504B1 (hu) |
NZ (1) | NZ532395A (hu) |
PL (1) | PL209826B1 (hu) |
PT (1) | PT1440082E (hu) |
RU (1) | RU2309160C2 (hu) |
WO (1) | WO2003035673A1 (hu) |
ZA (1) | ZA200402899B (hu) |
Families Citing this family (29)
Publication number | Priority date | Publication date | Assignee | Title |
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US6541606B2 (en) * | 1997-12-31 | 2003-04-01 | Altus Biologics Inc. | Stabilized protein crystals formulations containing them and methods of making them |
RU2309160C2 (ru) * | 2001-10-22 | 2007-10-27 | Домпе фа. р. ма с.п.а. | Способ получения микрочастиц белка или полипептида и продукт |
GB0300338D0 (en) * | 2003-01-08 | 2003-02-05 | Bradford Particle Design Ltd | Particle formation |
US7223445B2 (en) * | 2004-03-31 | 2007-05-29 | Eastman Kodak Company | Process for the deposition of uniform layer of particulate material |
DE102004049850A1 (de) * | 2004-09-15 | 2006-03-02 | Cognis Ip Management Gmbh | Verfahren und Anlage zur Herstellung von Mikropartikeln oder Nanopartikeln, Verwendung der Nanopartikel und damit hergestellte Suspension oder Emulsion |
CN1302766C (zh) * | 2005-06-23 | 2007-03-07 | 同济大学 | 超临界抗溶剂过程制备可生物降解聚合物载药微粒的方法 |
KR100705282B1 (ko) * | 2005-06-30 | 2007-04-12 | 주식회사 케이씨아이 | 유채씨로부터 분리 단백질을 제조하는 방법 |
US20100151469A1 (en) * | 2007-04-25 | 2010-06-17 | Wensheng Xia | Sample-processing reagent compositions, methods, and devices |
JP5628677B2 (ja) | 2007-10-19 | 2014-11-19 | ベクトン・ディキンソン・アンド・カンパニーBecton, Dickinson And Company | ベータ−ラクタマーゼの検出のための方法および組成物 |
WO2010047778A1 (en) | 2008-10-20 | 2010-04-29 | Becton Dickinson And Company | Compositions for the detection of intracellular bacterial targets and other intracellular microorganism targets |
US9138705B2 (en) | 2010-11-22 | 2015-09-22 | Hong Kong Polytechnic University | Method for precipitating a solute from a solution |
US9149045B2 (en) | 2010-12-07 | 2015-10-06 | Kimberly-Clark Worldwide, Inc. | Wipe coated with a botanical emulsion having antimicrobial properties |
US8445032B2 (en) | 2010-12-07 | 2013-05-21 | Kimberly-Clark Worldwide, Inc. | Melt-blended protein composition |
US9832993B2 (en) | 2010-12-07 | 2017-12-05 | Kimberly-Clark Worldwide, Inc. | Melt processed antimicrobial composition |
US8524264B2 (en) | 2010-12-07 | 2013-09-03 | Kimberly-Clark Worldwide, Inc. | Protein stabilized antimicrobial composition formed by melt processing |
US9648874B2 (en) | 2010-12-07 | 2017-05-16 | Kimberly-Clark Worldwide, Inc. | Natural, multiple use and re-use, user saturated wipes |
US10821085B2 (en) | 2010-12-07 | 2020-11-03 | Kimberly-Clark Worldwide, Inc. | Wipe coated with a botanical composition having antimicrobial properties |
US8574628B2 (en) | 2011-12-19 | 2013-11-05 | Kimberly-Clark Worldwide, Inc. | Natural, multiple release and re-use compositions |
US9925512B2 (en) | 2013-03-14 | 2018-03-27 | Crititech, Inc. | Equipment assembly for and method of processing particles |
US8778181B1 (en) | 2013-03-14 | 2014-07-15 | Crititech, Inc. | Equipment assembly for and method of processing particles |
US20160244547A1 (en) * | 2013-10-10 | 2016-08-25 | New York University | Efficient collection of nanoparticles |
EP3236720A4 (en) * | 2014-11-28 | 2018-10-10 | Zeon Corporation | Desmear processing method and manufacturing method for multilayer printed wiring board |
CN105727579B (zh) * | 2016-01-28 | 2018-01-09 | 苏州鼎烯聚材纳米科技有限公司 | 浆料的低成本高效率超临界喷雾干燥方法及设备 |
US10206873B1 (en) | 2017-08-04 | 2019-02-19 | Colorado Can Llc | Dry powder formation using a variably constrained, divided pathway for mixing fluid streams |
CN109430514B (zh) * | 2018-11-02 | 2022-07-26 | 广东海洋大学 | 一种制备罗非鱼-豆粕共沉淀蛋白的方法 |
KR102154923B1 (ko) * | 2019-03-05 | 2020-09-10 | 서울대학교산학협력단 | 배양액의 결정화 및 초임계 건조 장치 및 방법 |
CN110055238A (zh) * | 2019-05-13 | 2019-07-26 | 东北农业大学 | 一种海参花碱性磷酸酶的提取方法 |
CN114213382A (zh) * | 2021-12-10 | 2022-03-22 | 大连理工大学 | 一种基于超临界抗溶剂工艺合成微纳米级别egcg的方法 |
CN114831930B (zh) * | 2022-03-28 | 2023-09-05 | 厦门大学 | 一种胶原蛋白组装眼药、制备方法及应用 |
Family Cites Families (18)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
DE2748132A1 (de) | 1977-10-27 | 1979-05-03 | Behringwerke Ag | Stabilisator fuer polysaccharid |
JPS5874696A (ja) | 1981-10-30 | 1983-05-06 | 株式会社 ヤトロン | アデノシン三リン酸の安定化方法 |
US4457916A (en) | 1982-08-31 | 1984-07-03 | Asahi Kasei Kogyo Kabushiki Kaisha | Method for stabilizing Tumor Necrosis Factor and a stable aqueous solution or powder containing the same |
US4891319A (en) | 1985-07-09 | 1990-01-02 | Quadrant Bioresources Limited | Protection of proteins and the like |
US6063910A (en) | 1991-11-14 | 2000-05-16 | The Trustees Of Princeton University | Preparation of protein microparticles by supercritical fluid precipitation |
US5639441A (en) | 1992-03-06 | 1997-06-17 | Board Of Regents Of University Of Colorado | Methods for fine particle formation |
AU5171293A (en) | 1992-10-14 | 1994-05-09 | Regents Of The University Of Colorado, The | Ion-pairing of drugs for improved efficacy and delivery |
GB9313642D0 (en) | 1993-07-01 | 1993-08-18 | Glaxo Group Ltd | Method and apparatus for the formation of particles |
GB9413202D0 (en) * | 1994-06-30 | 1994-08-24 | Univ Bradford | Method and apparatus for the formation of particles |
US5874029A (en) | 1996-10-09 | 1999-02-23 | The University Of Kansas | Methods for particle micronization and nanonization by recrystallization from organic solutions sprayed into a compressed antisolvent |
GB9703673D0 (en) | 1997-02-21 | 1997-04-09 | Bradford Particle Design Ltd | Method and apparatus for the formation of particles |
GB9810559D0 (en) | 1998-05-15 | 1998-07-15 | Bradford Particle Design Ltd | Method and apparatus for particle formation |
GB9910975D0 (en) | 1999-05-13 | 1999-07-14 | Univ Strathclyde | Rapid dehydration of proteins |
EP1185248B1 (en) * | 1999-06-09 | 2012-05-02 | Robert E. Sievers | Supercritical fluid-assisted nebulization and bubble drying |
GB9915975D0 (en) * | 1999-07-07 | 1999-09-08 | Bradford Particle Design Ltd | Method for the formation of particles |
GB9920558D0 (en) | 1999-08-31 | 1999-11-03 | Bradford Particle Design Ltd | Methods for particle formation and their products |
KR100858956B1 (ko) * | 2001-02-26 | 2008-09-17 | 돔페 파르마 에스.피.에이. | 미세 및 초미세 입자를 형성하기 위한 장치 및 방법 |
RU2309160C2 (ru) * | 2001-10-22 | 2007-10-27 | Домпе фа. р. ма с.п.а. | Способ получения микрочастиц белка или полипептида и продукт |
-
2002
- 2002-10-21 RU RU2004112424/04A patent/RU2309160C2/ru not_active IP Right Cessation
- 2002-10-21 AT AT02785262T patent/ATE526340T1/de active
- 2002-10-21 ES ES02785262T patent/ES2372032T3/es not_active Expired - Lifetime
- 2002-10-21 CN CNA028209508A patent/CN1575298A/zh active Pending
- 2002-10-21 NZ NZ532395A patent/NZ532395A/xx not_active IP Right Cessation
- 2002-10-21 PL PL370303A patent/PL209826B1/pl unknown
- 2002-10-21 JP JP2003538186A patent/JP4374249B2/ja not_active Expired - Fee Related
- 2002-10-21 DK DK02785262.3T patent/DK1440082T3/da active
- 2002-10-21 BR BR0213430-6A patent/BR0213430A/pt not_active Application Discontinuation
- 2002-10-21 KR KR1020047005867A patent/KR100887429B1/ko not_active IP Right Cessation
- 2002-10-21 AU AU2002350588A patent/AU2002350588B2/en not_active Ceased
- 2002-10-21 WO PCT/EP2002/011761 patent/WO2003035673A1/en active Application Filing
- 2002-10-21 CA CA002464308A patent/CA2464308A1/en not_active Abandoned
- 2002-10-21 IL IL16144702A patent/IL161447A0/xx unknown
- 2002-10-21 MX MXPA04003718A patent/MXPA04003718A/es active IP Right Grant
- 2002-10-21 PT PT02785262T patent/PT1440082E/pt unknown
- 2002-10-21 EP EP02785262A patent/EP1440082B1/en not_active Expired - Lifetime
- 2002-10-21 HU HU0402096A patent/HUP0402096A3/hu unknown
- 2002-10-21 US US10/493,256 patent/US7250152B2/en not_active Expired - Fee Related
-
2004
- 2004-04-15 IL IL161447A patent/IL161447A/en not_active IP Right Cessation
- 2004-04-16 ZA ZA200402899A patent/ZA200402899B/en unknown
- 2004-04-21 NO NO20041634A patent/NO330504B1/no not_active IP Right Cessation
-
2007
- 2007-06-19 US US11/765,180 patent/US20070293655A1/en not_active Abandoned
Also Published As
Publication number | Publication date |
---|---|
DK1440082T3 (da) | 2012-01-16 |
PL209826B1 (pl) | 2011-10-31 |
US20070293655A1 (en) | 2007-12-20 |
ATE526340T1 (de) | 2011-10-15 |
BR0213430A (pt) | 2004-11-09 |
KR20040075856A (ko) | 2004-08-30 |
AU2002350588B2 (en) | 2008-08-28 |
US20050065063A1 (en) | 2005-03-24 |
EP1440082B1 (en) | 2011-09-28 |
IL161447A (en) | 2010-11-30 |
NO20041634L (no) | 2004-06-17 |
KR100887429B1 (ko) | 2009-03-09 |
CA2464308A1 (en) | 2003-05-01 |
NZ532395A (en) | 2006-03-31 |
ZA200402899B (en) | 2005-04-18 |
HUP0402096A3 (en) | 2012-09-28 |
IL161447A0 (en) | 2004-09-27 |
MXPA04003718A (es) | 2004-07-30 |
RU2309160C2 (ru) | 2007-10-27 |
PL370303A1 (en) | 2005-05-16 |
CN1575298A (zh) | 2005-02-02 |
US7250152B2 (en) | 2007-07-31 |
JP2005514341A (ja) | 2005-05-19 |
AU2002350588A2 (en) | 2003-05-06 |
PT1440082E (pt) | 2011-12-07 |
EP1440082A1 (en) | 2004-07-28 |
NO330504B1 (no) | 2011-05-02 |
ES2372032T3 (es) | 2012-01-13 |
JP4374249B2 (ja) | 2009-12-02 |
WO2003035673A9 (en) | 2003-11-13 |
RU2004112424A (ru) | 2005-10-10 |
WO2003035673A1 (en) | 2003-05-01 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
GB9A | Succession in title |
Owner name: DOMPE PHA.R.MA S.P.A., IT Free format text: FORMER OWNER(S): DOMPE S.P.A., IT |
|
FA9A | Lapse of provisional patent protection due to relinquishment or protection considered relinquished |