ZA200401154B - Antagonistic anit-hTNFSF13b human antibodies. - Google Patents
Antagonistic anit-hTNFSF13b human antibodies. Download PDFInfo
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- ZA200401154B ZA200401154B ZA200401154A ZA200401154A ZA200401154B ZA 200401154 B ZA200401154 B ZA 200401154B ZA 200401154 A ZA200401154 A ZA 200401154A ZA 200401154 A ZA200401154 A ZA 200401154A ZA 200401154 B ZA200401154 B ZA 200401154B
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- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/50—Immunoglobulins specific features characterized by immunoglobulin fragments
- C07K2317/56—Immunoglobulins specific features characterized by immunoglobulin fragments variable (Fv) region, i.e. VH and/or VL
- C07K2317/565—Complementarity determining region [CDR]
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/70—Immunoglobulins specific features characterized by effect upon binding to a cell or to an antigen
- C07K2317/73—Inducing cell death, e.g. apoptosis, necrosis or inhibition of cell proliferation
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/70—Immunoglobulins specific features characterized by effect upon binding to a cell or to an antigen
- C07K2317/76—Antagonist effect on antigen, e.g. neutralization or inhibition of binding
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/90—Immunoglobulins specific features characterized by (pharmaco)kinetic aspects or by stability of the immunoglobulin
- C07K2317/92—Affinity (KD), association rate (Ka), dissociation rate (Kd) or EC50 value
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- Medicinal Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Immunology (AREA)
- Pulmonology (AREA)
- Biochemistry (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Molecular Biology (AREA)
- Genetics & Genomics (AREA)
- Biophysics (AREA)
- Dermatology (AREA)
- Rheumatology (AREA)
- Pain & Pain Management (AREA)
- Oncology (AREA)
- Reproductive Health (AREA)
- Endocrinology (AREA)
- Physical Education & Sports Medicine (AREA)
- Orthopedic Medicine & Surgery (AREA)
- Communicable Diseases (AREA)
- Peptides Or Proteins (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US31280801P | 2001-08-16 | 2001-08-16 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ZA200401154B true ZA200401154B (en) | 2005-06-22 |
Family
ID=23213094
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ZA200401154A ZA200401154B (en) | 2001-08-16 | 2004-02-12 | Antagonistic anit-hTNFSF13b human antibodies. |
Country Status (26)
| Country | Link |
|---|---|
| US (4) | US7317089B2 (ja) |
| EP (2) | EP1432735B1 (ja) |
| JP (1) | JP4012880B2 (ja) |
| KR (1) | KR100961299B1 (ja) |
| CN (1) | CN100497392C (ja) |
| AR (1) | AR035119A1 (ja) |
| AU (2) | AU2002322436C1 (ja) |
| BR (1) | BR0211630A (ja) |
| CA (1) | CA2452447C (ja) |
| CO (1) | CO5560617A2 (ja) |
| DK (2) | DK2348048T3 (ja) |
| EA (1) | EA009074B1 (ja) |
| EC (1) | ECSP044978A (ja) |
| ES (2) | ES2389834T3 (ja) |
| HR (1) | HRP20040147A2 (ja) |
| HU (1) | HU230006B1 (ja) |
| IL (1) | IL160373A0 (ja) |
| MX (1) | MXPA04001344A (ja) |
| NO (1) | NO20040603L (ja) |
| NZ (1) | NZ530657A (ja) |
| PE (1) | PE20030334A1 (ja) |
| PL (1) | PL212404B1 (ja) |
| PT (2) | PT2348048E (ja) |
| UA (1) | UA89017C2 (ja) |
| WO (1) | WO2003016468A2 (ja) |
| ZA (1) | ZA200401154B (ja) |
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| US8212004B2 (en) * | 1999-03-02 | 2012-07-03 | Human Genome Sciences, Inc. | Neutrokine-alpha fusion proteins |
| US6812327B1 (en) * | 1996-10-25 | 2004-11-02 | Human Genome Sciences, Inc. | Neutrokine-alpha polypeptides |
| WO2002002641A1 (en) | 2000-06-16 | 2002-01-10 | Human Genome Sciences, Inc. | Antibodies that immunospecifically bind to blys |
| US7879328B2 (en) * | 2000-06-16 | 2011-02-01 | Human Genome Sciences, Inc. | Antibodies that immunospecifically bind to B lymphocyte stimulator |
| AU2001288301A1 (en) | 2000-08-18 | 2002-03-04 | Human Genome Sciences, Inc. | Binding polypeptides and methods based thereon |
| EE05294B1 (et) | 2001-05-11 | 2010-04-15 | Amgen Inc. | TALL-1-ga seostuv ainekompositsioon |
| WO2006025345A1 (ja) * | 2004-08-31 | 2006-03-09 | Kowa Company, Ltd. | 抗ヒトｂａｆｆ抗体 |
| AU2006246721B2 (en) | 2005-05-16 | 2012-12-13 | Abbvie Biotechnology Ltd | Use of TNF inhibitor for treatment of erosive polyarthritis |
| US9168286B2 (en) * | 2005-10-13 | 2015-10-27 | Human Genome Sciences, Inc. | Methods and compositions for use in treatment of patients with autoantibody positive disease |
| NZ568204A (en) | 2005-10-13 | 2012-01-12 | Human Genome Sciences Inc | Methods and compositions for use in treatment of patients with autoantibody positive diseases |
| US8202698B2 (en) | 2005-11-08 | 2012-06-19 | Biogen Idec Ma Inc. | Methods of evaluating BAFF |
| US8211649B2 (en) | 2006-03-31 | 2012-07-03 | Human Genome Sciences, Inc. | Methods of diagnosing and prognosing hodgkin's lymphoma |
| US9399061B2 (en) | 2006-04-10 | 2016-07-26 | Abbvie Biotechnology Ltd | Methods for determining efficacy of TNF-α inhibitors for treatment of rheumatoid arthritis |
| US9605064B2 (en) | 2006-04-10 | 2017-03-28 | Abbvie Biotechnology Ltd | Methods and compositions for treatment of skin disorders |
| CN102838599A (zh) | 2006-05-04 | 2012-12-26 | 贝林格尔.英格海姆国际有限公司 | 多晶型 |
| EP1852108A1 (en) | 2006-05-04 | 2007-11-07 | Boehringer Ingelheim Pharma GmbH & Co.KG | DPP IV inhibitor formulations |
| PE20080251A1 (es) | 2006-05-04 | 2008-04-25 | Boehringer Ingelheim Int | Usos de inhibidores de dpp iv |
| US8058402B2 (en) * | 2006-08-28 | 2011-11-15 | Kyowa Hakko Kirin | Antagonistic human LIGHT-specific human monoclonal antibodies |
| ES2627923T3 (es) * | 2007-01-11 | 2017-08-01 | Novo Nordisk A/S | Anticuerpos anti-KIR, formulaciones y usos de los mismos |
| PE20140960A1 (es) | 2008-04-03 | 2014-08-15 | Boehringer Ingelheim Int | Formulaciones que comprenden un inhibidor de dpp4 |
| US20200155558A1 (en) | 2018-11-20 | 2020-05-21 | Boehringer Ingelheim International Gmbh | Treatment for diabetes in patients with insufficient glycemic control despite therapy with an oral antidiabetic drug |
| WO2010093993A2 (en) | 2009-02-12 | 2010-08-19 | Human Genome Sciences, Inc. | Use of b lymphocyte stimulator protein antagonists to promote transplantation tolerance |
| US9034883B2 (en) | 2010-11-15 | 2015-05-19 | Boehringer Ingelheim International Gmbh | Vasoprotective and cardioprotective antidiabetic therapy |
| CN109022465B (zh) | 2011-10-28 | 2022-04-29 | 特瓦制药澳大利亚私人有限公司 | 多肽构建体及其用途 |
| AR090626A1 (es) * | 2012-04-20 | 2014-11-26 | Lilly Co Eli | Anticuerpos anti-baff-anti-il-17 biespecificos |
| CA2877397A1 (en) | 2012-07-03 | 2014-01-09 | Washington University | Antibodies to tau |
| JOP20140087B1 (ar) | 2013-03-13 | 2021-08-17 | Amgen Inc | بروتينات مخصصة ل baff و b7rp1 وإستخداماتها |
| US9458246B2 (en) | 2013-03-13 | 2016-10-04 | Amgen Inc. | Proteins specific for BAFF and B7RP1 |
| US9700485B2 (en) | 2013-04-24 | 2017-07-11 | Corning Incorporated | Delamination resistant pharmaceutical glass containers containing active pharmaceutical ingredients |
| DK3677591T5 (da) | 2013-04-29 | 2024-08-26 | Teva Pharmaceuticals Australia Pty Ltd | Anti-CD38 antistoffer og fusioner til svækket interferon alpha-2b |
| US11117975B2 (en) | 2013-04-29 | 2021-09-14 | Teva Pharmaceuticals Australia Pty Ltd | Anti-CD38 antibodies and fusions to attenuated interferon alpha-2B |
| US10435474B2 (en) | 2013-12-24 | 2019-10-08 | Ossianix, Inc. | Baff selective binding compounds and related methods |
| BR112016014731A2 (pt) * | 2014-01-31 | 2017-09-19 | Boehringer Ingelheim Int | Anticorpos anti-baff |
| UA119352C2 (uk) | 2014-05-01 | 2019-06-10 | Тева Фармасьютикалз Острейліа Пті Лтд | Комбінація леналідоміду або помалідоміду і конструкції анти-cd38 антитіло-атенуйований інтерферон альфа-2b та спосіб лікування суб'єкта, який має cd38-експресуючу пухлину |
| TWI694836B (zh) | 2014-05-16 | 2020-06-01 | 英商葛蘭素史克智慧財產管理有限公司 | 抗體調配物 |
| US20170101466A1 (en) * | 2014-06-03 | 2017-04-13 | Masahisa Handa | Anti-blys antibodies |
| TW202136296A (zh) | 2014-06-27 | 2021-10-01 | 美商Ｃ２Ｎ醫療診斷有限責任公司 | 人類化抗-tau抗體 |
| PE20170908A1 (es) | 2014-10-29 | 2017-07-12 | Teva Pharmaceuticals Australia Pty Ltd | VARIANTES DE INTERFERON a2b |
| AR104368A1 (es) * | 2015-04-03 | 2017-07-19 | Lilly Co Eli | Anticuerpos biespecíficos anti-cd20- / anti-baff |
| CN118515767B (zh) * | 2024-07-23 | 2024-10-18 | 江苏双全生物医药科技有限公司 | 一种TNFSF13b抗体及其应用 |
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| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5789650A (en) | 1990-08-29 | 1998-08-04 | Genpharm International, Inc. | Transgenic non-human animals for producing heterologous antibodies |
| US5877397A (en) | 1990-08-29 | 1999-03-02 | Genpharm International Inc. | Transgenic non-human animals capable of producing heterologous antibodies of various isotypes |
| DK0814159T3 (da) | 1990-08-29 | 2005-10-24 | Genpharm Int | Transgene, ikke-humane dyr, der er i stand til at danne heterologe antistoffer |
| US5874299A (en) | 1990-08-29 | 1999-02-23 | Genpharm International, Inc. | Transgenic non-human animals capable of producing heterologous antibodies |
| US5625126A (en) | 1990-08-29 | 1997-04-29 | Genpharm International, Inc. | Transgenic non-human animals for producing heterologous antibodies |
| US5770429A (en) | 1990-08-29 | 1998-06-23 | Genpharm International, Inc. | Transgenic non-human animals capable of producing heterologous antibodies |
| US5633425A (en) | 1990-08-29 | 1997-05-27 | Genpharm International, Inc. | Transgenic non-human animals capable of producing heterologous antibodies |
| US5661016A (en) | 1990-08-29 | 1997-08-26 | Genpharm International Inc. | Transgenic non-human animals capable of producing heterologous antibodies of various isotypes |
| US5814318A (en) | 1990-08-29 | 1998-09-29 | Genpharm International Inc. | Transgenic non-human animals for producing heterologous antibodies |
| US5545806A (en) | 1990-08-29 | 1996-08-13 | Genpharm International, Inc. | Ransgenic non-human animals for producing heterologous antibodies |
| US6096878A (en) * | 1993-05-10 | 2000-08-01 | Japan Tobacco Inc. | Human immunoglobulin VH gene segments and DNA fragments containing the same |
| ATE302272T1 (de) | 1996-10-25 | 2005-09-15 | Human Genome Sciences Inc | Neutrokin alpha |
| US6812327B1 (en) * | 1996-10-25 | 2004-11-02 | Human Genome Sciences, Inc. | Neutrokine-alpha polypeptides |
| AU5705898A (en) | 1996-12-17 | 1998-07-15 | Schering Corporation | Mammalian cell surface antigens; related reagents |
| EA200000311A1 (ru) | 1997-09-12 | 2000-10-30 | Апотек Р Энд Д Са | Новый белок иммунной системы - кау |
| US6297367B1 (en) * | 1997-12-30 | 2001-10-02 | Chiron Corporation | Polynucleotide encoding TNFL1 |
| US6787638B1 (en) | 1998-12-02 | 2004-09-07 | Applied Molecular Evolution, Inc. | Tumor specific human monoclonal antibodies and methods of use |
| DK1146892T3 (da) | 1999-01-25 | 2003-11-24 | Apoxis Sa | BAFF, inhibitorer deraf og deres anvendelse i modulationen af B-celle responset |
| NZ513290A (en) | 1999-02-23 | 2004-05-28 | Human Genome Sciences Inc | Neutrokine-alpha and neutrokine-alpha splice variant |
| WO2002002641A1 (en) | 2000-06-16 | 2002-01-10 | Human Genome Sciences, Inc. | Antibodies that immunospecifically bind to blys |
-
2002
- 2002-08-13 AR ARP020103052A patent/AR035119A1/es not_active Application Discontinuation
- 2002-08-15 MX MXPA04001344A patent/MXPA04001344A/es active IP Right Grant
- 2002-08-15 AU AU2002322436A patent/AU2002322436C1/en not_active Ceased
- 2002-08-15 US US10/484,790 patent/US7317089B2/en not_active Expired - Fee Related
- 2002-08-15 CN CNB028159217A patent/CN100497392C/zh not_active Expired - Fee Related
- 2002-08-15 PT PT101846756T patent/PT2348048E/pt unknown
- 2002-08-15 BR BR0211630-8A patent/BR0211630A/pt not_active IP Right Cessation
- 2002-08-15 DK DK10184675.6T patent/DK2348048T3/en active
- 2002-08-15 HU HU0500816A patent/HU230006B1/hu not_active IP Right Cessation
- 2002-08-15 PL PL370534A patent/PL212404B1/pl unknown
- 2002-08-15 EP EP02756428A patent/EP1432735B1/en not_active Expired - Lifetime
- 2002-08-15 EA EA200400312A patent/EA009074B1/ru not_active IP Right Cessation
- 2002-08-15 DK DK02756428.5T patent/DK1432735T3/da active
- 2002-08-15 JP JP2003521777A patent/JP4012880B2/ja not_active Expired - Fee Related
- 2002-08-15 CA CA2452447A patent/CA2452447C/en not_active Expired - Fee Related
- 2002-08-15 IL IL16037302A patent/IL160373A0/xx unknown
- 2002-08-15 EP EP10184675.6A patent/EP2348048B1/en not_active Expired - Lifetime
- 2002-08-15 KR KR1020047002203A patent/KR100961299B1/ko not_active IP Right Cessation
- 2002-08-15 UA UA2004021088A patent/UA89017C2/uk unknown
- 2002-08-15 ES ES02756428T patent/ES2389834T3/es not_active Expired - Lifetime
- 2002-08-15 PT PT02756428T patent/PT1432735E/pt unknown
- 2002-08-15 NZ NZ530657A patent/NZ530657A/en unknown
- 2002-08-15 ES ES10184675.6T patent/ES2526990T3/es not_active Expired - Lifetime
- 2002-08-15 WO PCT/US2002/021842 patent/WO2003016468A2/en active Search and Examination
- 2002-08-16 PE PE2002000745A patent/PE20030334A1/es not_active Application Discontinuation
-
2004
- 2004-02-10 NO NO20040603A patent/NO20040603L/no not_active Application Discontinuation
- 2004-02-12 ZA ZA200401154A patent/ZA200401154B/en unknown
- 2004-02-13 EC EC2004004978A patent/ECSP044978A/es unknown
- 2004-02-13 CO CO04012060A patent/CO5560617A2/es not_active Application Discontinuation
- 2004-02-16 HR HR20040147A patent/HRP20040147A2/hr not_active Application Discontinuation
-
2007
- 2007-12-07 US US11/952,363 patent/US7728109B2/en not_active Expired - Fee Related
-
2008
- 2008-11-20 AU AU2008246261A patent/AU2008246261B2/en not_active Ceased
-
2010
- 2010-05-11 US US12/777,306 patent/US8173124B2/en not_active Expired - Fee Related
-
2012
- 2012-04-11 US US13/444,216 patent/US20120195904A1/en not_active Abandoned
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