ZA200304557B - Tetrahydro-(benzo or thieno)-azepine-pyrazine and triazine derivatives as mGluR 1 antagonists. - Google Patents
Tetrahydro-(benzo or thieno)-azepine-pyrazine and triazine derivatives as mGluR 1 antagonists. Download PDFInfo
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- ZA200304557B ZA200304557B ZA200304557A ZA200304557A ZA200304557B ZA 200304557 B ZA200304557 B ZA 200304557B ZA 200304557 A ZA200304557 A ZA 200304557A ZA 200304557 A ZA200304557 A ZA 200304557A ZA 200304557 B ZA200304557 B ZA 200304557B
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Classifications
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- C07D403/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings
- C07D403/04—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings directly linked by a ring-member-to-ring-member bond
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- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/55—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having seven-membered rings, e.g. azelastine, pentylenetetrazole
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- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
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- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D495/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms
- C07D495/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms in which the condensed system contains two hetero rings
- C07D495/04—Ortho-condensed systems
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- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
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- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
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- Life Sciences & Earth Sciences (AREA)
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- Heart & Thoracic Surgery (AREA)
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- Otolaryngology (AREA)
- Vascular Medicine (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
- Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| EP00128329 | 2000-12-22 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ZA200304557B true ZA200304557B (en) | 2004-09-13 |
Family
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| ZA200304557A ZA200304557B (en) | 2000-12-22 | 2003-06-11 | Tetrahydro-(benzo or thieno)-azepine-pyrazine and triazine derivatives as mGluR 1 antagonists. |
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| EP (1) | EP1345609B1 (https=) |
| JP (1) | JP4077319B2 (https=) |
| KR (1) | KR100545906B1 (https=) |
| CN (1) | CN1260226C (https=) |
| AR (1) | AR032379A1 (https=) |
| AT (1) | ATE297734T1 (https=) |
| AU (1) | AU2002216095B2 (https=) |
| BR (1) | BR0116378A (https=) |
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| WO (1) | WO2002051418A1 (https=) |
| ZA (1) | ZA200304557B (https=) |
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| EP2258358A3 (en) | 2005-08-26 | 2011-09-07 | Braincells, Inc. | Neurogenesis with acetylcholinesterase inhibitor |
| EP2275095A3 (en) | 2005-08-26 | 2011-08-17 | Braincells, Inc. | Neurogenesis by muscarinic receptor modulation |
| EP1940389A2 (en) | 2005-10-21 | 2008-07-09 | Braincells, Inc. | Modulation of neurogenesis by pde inhibition |
| AU2006308889A1 (en) | 2005-10-31 | 2007-05-10 | Braincells, Inc. | GABA receptor mediated modulation of neurogenesis |
| KR101503681B1 (ko) | 2006-01-19 | 2015-03-19 | 아더시스 인코포레이티드 | 세로토닌 5-ｈｔ2ｃ 수용체 리간드로서의 티오페닐 및 피롤릴 아제핀 및 이의 용도 |
| US20100216734A1 (en) | 2006-03-08 | 2010-08-26 | Braincells, Inc. | Modulation of neurogenesis by nootropic agents |
| JP2009536667A (ja) | 2006-05-09 | 2009-10-15 | ブレインセルス，インコーポレイティド | ５ｈｔ受容体介在性の神経新生 |
| EP2382975A3 (en) | 2006-05-09 | 2012-02-29 | Braincells, Inc. | Neurogenesis by modulating angiotensin |
| AU2007292848A1 (en) | 2006-09-08 | 2008-03-13 | Braincells, Inc. | Combinations containing a 4-acylaminopyridine derivative |
| US20100184806A1 (en) | 2006-09-19 | 2010-07-22 | Braincells, Inc. | Modulation of neurogenesis by ppar agents |
| WO2010099217A1 (en) | 2009-02-25 | 2010-09-02 | Braincells, Inc. | Modulation of neurogenesis using d-cycloserine combinations |
| KR101100864B1 (ko) * | 2009-06-12 | 2012-01-02 | 양준호 | 자동차 광택기용 광택패드 |
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| DE3136654A1 (de) | 1981-09-16 | 1983-03-31 | Zahnradfabrik Friedrichshafen Ag, 7990 Friedrichshafen | Linearverschieblicher arbeitsarm, insbesondere fuer handhabungsgeraete |
| AU2642699A (en) * | 1998-03-03 | 1999-09-20 | Yamanouchi Pharmaceutical Co., Ltd. | Remedies for brain infarction |
| ID29095A (id) * | 1998-10-02 | 2001-07-26 | Novartis Ag Cs | Antagonis mglur5 untuk pengobatan rasa sakit dan kegelisahan |
| GB9823847D0 (en) * | 1998-11-02 | 1998-12-23 | Lilly Co Eli | Pharmaceutical compounds |
| EP1074549B1 (en) * | 1999-08-06 | 2003-11-19 | F. Hoffmann-La Roche Ag | Tetrahydro-benzo(d)azepines and their use as antagonists at metabotropic glutamate receptors |
| ES2209728T3 (es) * | 1999-08-06 | 2004-07-01 | F. Hoffmann-La Roche Ag | Tetrahidro-benzo(d)azepinas y su uso como antagonistas de receptores de glutamato metabotropico. |
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- 2001-12-11 DE DE60111568T patent/DE60111568T2/de not_active Expired - Lifetime
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2003
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Also Published As
| Publication number | Publication date |
|---|---|
| MXPA03005515A (es) | 2003-09-25 |
| DE60111568T2 (de) | 2006-05-11 |
| KR20030062444A (ko) | 2003-07-25 |
| ATE297734T1 (de) | 2005-07-15 |
| DE60111568D1 (de) | 2005-07-21 |
| CA2432077C (en) | 2011-01-18 |
| JP4077319B2 (ja) | 2008-04-16 |
| US6586422B2 (en) | 2003-07-01 |
| CN1487831A (zh) | 2004-04-07 |
| KR100545906B1 (ko) | 2006-01-26 |
| DK1345609T3 (da) | 2005-10-03 |
| ES2243400T3 (es) | 2005-12-01 |
| US20020123488A1 (en) | 2002-09-05 |
| AR032379A1 (es) | 2003-11-05 |
| CA2432077A1 (en) | 2002-07-04 |
| PT1345609E (pt) | 2005-08-31 |
| AU2002216095B2 (en) | 2005-12-01 |
| CN1260226C (zh) | 2006-06-21 |
| WO2002051418A1 (en) | 2002-07-04 |
| EP1345609A1 (en) | 2003-09-24 |
| JP2004517850A (ja) | 2004-06-17 |
| EP1345609B1 (en) | 2005-06-15 |
| BR0116378A (pt) | 2003-10-28 |
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