ZA200303935B - Skin care product containing retinoids and phytoestrogens in a dual compartment package. - Google Patents
Skin care product containing retinoids and phytoestrogens in a dual compartment package. Download PDFInfo
- Publication number
- ZA200303935B ZA200303935B ZA200303935A ZA200303935A ZA200303935B ZA 200303935 B ZA200303935 B ZA 200303935B ZA 200303935 A ZA200303935 A ZA 200303935A ZA 200303935 A ZA200303935 A ZA 200303935A ZA 200303935 B ZA200303935 B ZA 200303935B
- Authority
- ZA
- South Africa
- Prior art keywords
- skin
- care product
- compositions
- composition
- retinyl
- Prior art date
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- 239000003075 phytoestrogen Substances 0.000 title claims abstract description 26
- 230000009977 dual effect Effects 0.000 title description 10
- 239000000203 mixture Substances 0.000 claims abstract description 60
- 150000004492 retinoid derivatives Chemical class 0.000 claims abstract description 19
- FPIPGXGPPPQFEQ-OVSJKPMPSA-N all-trans-retinol Chemical compound OC\C=C(/C)\C=C\C=C(/C)\C=C\C1=C(C)CCCC1(C)C FPIPGXGPPPQFEQ-OVSJKPMPSA-N 0.000 claims description 67
- 210000003491 skin Anatomy 0.000 claims description 48
- FPIPGXGPPPQFEQ-UHFFFAOYSA-N 13-cis retinol Natural products OCC=C(C)C=CC=C(C)C=CC1=C(C)CCCC1(C)C FPIPGXGPPPQFEQ-UHFFFAOYSA-N 0.000 claims description 37
- ZQSIJRDFPHDXIC-UHFFFAOYSA-N daidzein Chemical compound C1=CC(O)=CC=C1C1=COC2=CC(O)=CC=C2C1=O ZQSIJRDFPHDXIC-UHFFFAOYSA-N 0.000 claims description 32
- 229960003471 retinol Drugs 0.000 claims description 31
- 235000020944 retinol Nutrition 0.000 claims description 31
- 239000011607 retinol Substances 0.000 claims description 31
- 235000006539 genistein Nutrition 0.000 claims description 26
- TZBJGXHYKVUXJN-UHFFFAOYSA-N genistein Natural products C1=CC(O)=CC=C1C1=COC2=CC(O)=CC(O)=C2C1=O TZBJGXHYKVUXJN-UHFFFAOYSA-N 0.000 claims description 26
- 229940045109 genistein Drugs 0.000 claims description 26
- ZCOLJUOHXJRHDI-CMWLGVBASA-N genistein 7-O-beta-D-glucoside Chemical compound O[C@@H]1[C@@H](O)[C@H](O)[C@@H](CO)O[C@H]1OC1=CC(O)=C2C(=O)C(C=3C=CC(O)=CC=3)=COC2=C1 ZCOLJUOHXJRHDI-CMWLGVBASA-N 0.000 claims description 26
- 230000008901 benefit Effects 0.000 claims description 17
- 235000007240 daidzein Nutrition 0.000 claims description 16
- SHGAZHPCJJPHSC-YCNIQYBTSA-N all-trans-retinoic acid Chemical compound OC(=O)\C=C(/C)\C=C\C=C(/C)\C=C\C1=C(C)CCCC1(C)C SHGAZHPCJJPHSC-YCNIQYBTSA-N 0.000 claims description 12
- 229930002330 retinoic acid Natural products 0.000 claims description 12
- 229960001727 tretinoin Drugs 0.000 claims description 12
- 238000000034 method Methods 0.000 claims description 7
- 125000000946 retinyl group Chemical group [H]C([*])([H])/C([H])=C(C([H])([H])[H])/C([H])=C([H])/C([H])=C(C([H])([H])[H])/C([H])=C([H])/C1=C(C([H])([H])[H])C([H])([H])C([H])([H])C([H])([H])C1(C([H])([H])[H])C([H])([H])[H] 0.000 claims description 7
- 230000001965 increasing effect Effects 0.000 claims description 6
- 208000002874 Acne Vulgaris Diseases 0.000 claims description 5
- 206010000496 acne Diseases 0.000 claims description 5
- 230000004069 differentiation Effects 0.000 claims description 5
- 230000037303 wrinkles Effects 0.000 claims description 5
- 206010013786 Dry skin Diseases 0.000 claims description 4
- WUADCCWRTIWANL-UHFFFAOYSA-N biochanin A Chemical compound C1=CC(OC)=CC=C1C1=COC2=CC(O)=CC(O)=C2C1=O WUADCCWRTIWANL-UHFFFAOYSA-N 0.000 claims description 4
- 230000003750 conditioning effect Effects 0.000 claims description 4
- 230000037336 dry skin Effects 0.000 claims description 4
- 230000002500 effect on skin Effects 0.000 claims description 4
- HKQYGTCOTHHOMP-UHFFFAOYSA-N formononetin Chemical compound C1=CC(OC)=CC=C1C1=COC2=CC(O)=CC=C2C1=O HKQYGTCOTHHOMP-UHFFFAOYSA-N 0.000 claims description 4
- OZBAVEKZGSOMOJ-MIUGBVLSSA-N glycitin Chemical compound COC1=CC(C(C(C=2C=CC(O)=CC=2)=CO2)=O)=C2C=C1O[C@@H]1O[C@H](CO)[C@@H](O)[C@H](O)[C@H]1O OZBAVEKZGSOMOJ-MIUGBVLSSA-N 0.000 claims description 4
- 206010051246 Photodermatosis Diseases 0.000 claims description 3
- 206010040844 Skin exfoliation Diseases 0.000 claims description 3
- 230000029142 excretion Effects 0.000 claims description 3
- 210000002374 sebum Anatomy 0.000 claims description 3
- 208000010744 skin desquamation Diseases 0.000 claims description 3
- 210000000434 stratum corneum Anatomy 0.000 claims description 3
- XJTZHGNBKZYODI-UHFFFAOYSA-N Glycitin Natural products OCC1OC(Oc2ccc3OC=C(C(=O)c3c2CO)c4ccc(O)cc4)C(O)C(O)C1O XJTZHGNBKZYODI-UHFFFAOYSA-N 0.000 claims description 2
- ADFCQWZHKCXPAJ-GFCCVEGCSA-N equol Chemical compound C1=CC(O)=CC=C1[C@@H]1CC2=CC=C(O)C=C2OC1 ADFCQWZHKCXPAJ-GFCCVEGCSA-N 0.000 claims description 2
- 235000019126 equol Nutrition 0.000 claims description 2
- RIKPNWPEMPODJD-UHFFFAOYSA-N formononetin Natural products C1=CC(OC)=CC=C1C1=COC2=CC=CC=C2C1=O RIKPNWPEMPODJD-UHFFFAOYSA-N 0.000 claims description 2
- ADFCQWZHKCXPAJ-UHFFFAOYSA-N indofine Natural products C1=CC(O)=CC=C1C1CC2=CC=C(O)C=C2OC1 ADFCQWZHKCXPAJ-UHFFFAOYSA-N 0.000 claims description 2
- 230000002207 retinal effect Effects 0.000 claims description 2
- NCYCYZXNIZJOKI-OVSJKPMPSA-N retinal group Chemical group C\C(=C/C=O)\C=C\C=C(\C=C\C1=C(CCCC1(C)C)C)/C NCYCYZXNIZJOKI-OVSJKPMPSA-N 0.000 claims description 2
- 230000002195 synergetic effect Effects 0.000 claims description 2
- 239000003814 drug Substances 0.000 claims 3
- 239000011604 retinal Substances 0.000 claims 1
- QGNJRVVDBSJHIZ-QHLGVNSISA-N retinyl acetate Chemical compound CC(=O)OC\C=C(/C)\C=C\C=C(/C)\C=C\C1=C(C)CCCC1(C)C QGNJRVVDBSJHIZ-QHLGVNSISA-N 0.000 description 14
- 210000004027 cell Anatomy 0.000 description 13
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- 108050008825 Cellular retinoic acid-binding protein 2 Proteins 0.000 description 12
- 102100038504 Cellular retinoic acid-binding protein 2 Human genes 0.000 description 12
- VYGQUTWHTHXGQB-FFHKNEKCSA-N Retinol Palmitate Chemical compound CCCCCCCCCCCCCCCC(=O)OC\C=C(/C)\C=C\C=C(/C)\C=C\C1=C(C)CCCC1(C)C VYGQUTWHTHXGQB-FFHKNEKCSA-N 0.000 description 12
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- 150000001875 compounds Chemical class 0.000 description 6
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- 239000011769 retinyl palmitate Substances 0.000 description 6
- 239000002253 acid Substances 0.000 description 5
- 239000003795 chemical substances by application Substances 0.000 description 5
- 239000000262 estrogen Substances 0.000 description 5
- 210000002950 fibroblast Anatomy 0.000 description 5
- XWCYDHJOKKGVHC-UHFFFAOYSA-N Vitamin A2 Chemical compound OCC=C(C)C=CC=C(C)C=CC1=C(C)C=CCC1(C)C XWCYDHJOKKGVHC-UHFFFAOYSA-N 0.000 description 4
- 230000015572 biosynthetic process Effects 0.000 description 4
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- 235000004626 essential fatty acids Nutrition 0.000 description 4
- 229940011871 estrogen Drugs 0.000 description 4
- DXGLGDHPHMLXJC-UHFFFAOYSA-N oxybenzone Chemical compound OC1=CC(OC)=CC=C1C(=O)C1=CC=CC=C1 DXGLGDHPHMLXJC-UHFFFAOYSA-N 0.000 description 4
- 239000000243 solution Substances 0.000 description 4
- 239000006228 supernatant Substances 0.000 description 4
- 239000002562 thickening agent Substances 0.000 description 4
- IAZDPXIOMUYVGZ-UHFFFAOYSA-N Dimethylsulphoxide Chemical compound CS(C)=O IAZDPXIOMUYVGZ-UHFFFAOYSA-N 0.000 description 3
- 239000006144 Dulbecco’s modified Eagle's medium Substances 0.000 description 3
- YBGZDTIWKVFICR-JLHYYAGUSA-N Octyl 4-methoxycinnamic acid Chemical compound CCCCC(CC)COC(=O)\C=C\C1=CC=C(OC)C=C1 YBGZDTIWKVFICR-JLHYYAGUSA-N 0.000 description 3
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Classifications
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- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q19/00—Preparations for care of the skin
- A61Q19/004—Aftersun preparations
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- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/67—Vitamins
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/045—Hydroxy compounds, e.g. alcohols; Salts thereof, e.g. alcoholates
- A61K31/07—Retinol compounds, e.g. vitamin A
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- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/335—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
- A61K31/35—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having six-membered rings with one oxygen as the only ring hetero atom
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- A—HUMAN NECESSITIES
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- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/49—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing heterocyclic compounds
- A61K8/4973—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing heterocyclic compounds with oxygen as the only hetero atom
- A61K8/498—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing heterocyclic compounds with oxygen as the only hetero atom having 6-membered rings or their condensed derivatives, e.g. coumarin
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- A—HUMAN NECESSITIES
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- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/63—Steroids; Derivatives thereof
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/67—Vitamins
- A61K8/671—Vitamin A; Derivatives thereof, e.g. ester of vitamin A acid, ester of retinol, retinol, retinal
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A61P17/10—Anti-acne agents
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q19/00—Preparations for care of the skin
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q19/00—Preparations for care of the skin
- A61Q19/02—Preparations for care of the skin for chemically bleaching or whitening the skin
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
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- A61Q19/08—Anti-ageing preparations
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2800/00—Properties of cosmetic compositions or active ingredients thereof or formulation aids used therein and process related aspects
- A61K2800/70—Biological properties of the composition as a whole
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2800/00—Properties of cosmetic compositions or active ingredients thereof or formulation aids used therein and process related aspects
- A61K2800/80—Process related aspects concerning the preparation of the cosmetic composition or the storage or application thereof
- A61K2800/88—Two- or multipart kits
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Epidemiology (AREA)
- Dermatology (AREA)
- Birds (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Chemical & Material Sciences (AREA)
- Gerontology & Geriatric Medicine (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Engineering & Computer Science (AREA)
- Organic Chemistry (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Cosmetics (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Medicinal Preparation (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US25845600P | 2000-12-28 | 2000-12-28 |
Publications (1)
Publication Number | Publication Date |
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ZA200303935B true ZA200303935B (en) | 2004-05-21 |
Family
ID=22980614
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
ZA200303935A ZA200303935B (en) | 2000-12-28 | 2001-12-06 | Skin care product containing retinoids and phytoestrogens in a dual compartment package. |
Country Status (12)
Country | Link |
---|---|
US (1) | US6565864B2 (fr) |
EP (1) | EP1349537B1 (fr) |
JP (1) | JP4451062B2 (fr) |
KR (1) | KR100827045B1 (fr) |
CN (1) | CN1287764C (fr) |
AT (1) | ATE344014T1 (fr) |
AU (1) | AU2002233236B2 (fr) |
CA (1) | CA2431391A1 (fr) |
DE (1) | DE60124307T2 (fr) |
MX (1) | MXPA03005705A (fr) |
WO (1) | WO2002053122A2 (fr) |
ZA (1) | ZA200303935B (fr) |
Families Citing this family (15)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US8668914B2 (en) * | 2002-07-24 | 2014-03-11 | Brigham Young University | Use of equol for treating skin diseases |
WO2004039327A2 (fr) | 2002-10-29 | 2004-05-13 | Colorado State University Research Foundation | Utilisation d'equol dans le traitement de maladies d'origine androgenique |
EP1545206B1 (fr) | 2002-07-24 | 2020-03-04 | Children's Hospital Medical Center | Compositions et produits contenant de l'equol enantiomere, et procedes de fabrication |
US8580846B2 (en) | 2002-10-29 | 2013-11-12 | Brigham Young University | Use of equol for ameliorating or preventing neuropsychiatric and neurodegenerative diseases or disorders |
KR20040043703A (ko) * | 2002-11-16 | 2004-05-27 | (주)라렌드몽드 | 레티노이드를 함유한 화학 박피제 |
EP1677747A1 (fr) * | 2003-10-31 | 2006-07-12 | The Procter & Gamble Company | Procede de preparation d'une composition melangee |
EP2305272A1 (fr) * | 2004-04-28 | 2011-04-06 | Brigham Young University | Utilisation de l'equol dans le traitement des maladies de la peau |
EP1878421B1 (fr) | 2005-04-28 | 2019-04-03 | SBI Pharmaceuticals Co., Ltd. | Preparation cutanee externe |
US20070254025A1 (en) * | 2006-04-27 | 2007-11-01 | Cronk Peter J | Oral contraceptive and acne medication combination and treatment of acne with reduced side effects |
US20070254858A1 (en) * | 2006-04-27 | 2007-11-01 | Cronk Peter J | Contraceptive and Acne Medication Combination and Treatment of Acne and Other Diseases with Reduced Side Effects |
AU2008262870B2 (en) * | 2007-06-13 | 2013-07-11 | Otsuka Pharmaceutical Co., Ltd. | Equol-containing extract, method for production thereof, method for extraction of equol, and equol-containing food |
US9554746B1 (en) * | 2013-04-18 | 2017-01-31 | Escape Therapeutics, Inc. | System for evaluating skin treatment |
US10076479B1 (en) | 2018-05-08 | 2018-09-18 | Avon Products, Inc. | Methods for treating skin |
BR112017019054B1 (pt) | 2015-03-05 | 2021-05-11 | Avon Products, Inc | método cosmético, não terapêutico, para diminuir sinais dermatológicos de envelhecimento em pele humana e produtos para cuidados com a pele |
JP6316391B2 (ja) * | 2016-12-05 | 2018-04-25 | 花王株式会社 | レチノイン酸様剤 |
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US5750570A (en) | 1992-03-31 | 1998-05-12 | The Regents Of The University Of Michigan | Method of treatment of hyperpigmentation in black skin with retinoic acid and method of lightening black skin with retinoic acid |
FR2725897B1 (fr) * | 1994-10-24 | 1996-12-06 | Oreal | Produit pour application topique contenant une lipase et un precurseur d'actif |
US5795910A (en) | 1994-10-28 | 1998-08-18 | Cor Therapeutics, Inc. | Method and compositions for inhibiting protein kinases |
WO1996037420A1 (fr) * | 1995-05-26 | 1996-11-28 | Unilever Plc | Cure de soins cutanes |
US5536740A (en) * | 1995-06-01 | 1996-07-16 | Elizabeth Arden Company, Division Of Conopco, Inc. | Skin care compositions containing dimethyl imidazolidinone and retinol or retinyl ester |
US5834513A (en) * | 1996-04-25 | 1998-11-10 | Avon Products, Inc. | Oxa diacids and related compounds for treating skin conditions |
US5847003A (en) | 1996-06-04 | 1998-12-08 | Avon Products, Inc. | Oxa acids and related compounds for treating skin conditions |
FR2782919B1 (fr) * | 1998-09-04 | 2001-05-25 | Roc Sa | Composition contre le vieillissement et son utilisation |
GB9918025D0 (en) * | 1999-07-30 | 1999-09-29 | Unilever Plc | Skin care composition |
US6358517B1 (en) * | 1999-10-22 | 2002-03-19 | Unilever Home & Personal Care Usa, Division Of Conopco | Cosmetic compositions containing resveratrol and retinoids |
MXPA02004933A (es) * | 1999-11-16 | 2004-08-12 | Unilever Nv | Composiciones cosmeticas conteniendo extracto de garbanzo y retinoides. |
-
2001
- 2001-11-07 US US10/036,589 patent/US6565864B2/en not_active Expired - Fee Related
- 2001-12-06 AU AU2002233236A patent/AU2002233236B2/en not_active Ceased
- 2001-12-06 ZA ZA200303935A patent/ZA200303935B/en unknown
- 2001-12-06 EP EP01984818A patent/EP1349537B1/fr not_active Expired - Lifetime
- 2001-12-06 AT AT01984818T patent/ATE344014T1/de not_active IP Right Cessation
- 2001-12-06 KR KR1020037008747A patent/KR100827045B1/ko not_active IP Right Cessation
- 2001-12-06 DE DE60124307T patent/DE60124307T2/de not_active Expired - Lifetime
- 2001-12-06 WO PCT/EP2001/014483 patent/WO2002053122A2/fr active IP Right Grant
- 2001-12-06 JP JP2002554073A patent/JP4451062B2/ja not_active Expired - Fee Related
- 2001-12-06 CA CA002431391A patent/CA2431391A1/fr not_active Abandoned
- 2001-12-06 CN CNB018216269A patent/CN1287764C/zh not_active Expired - Fee Related
- 2001-12-06 MX MXPA03005705A patent/MXPA03005705A/es active IP Right Grant
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MXPA03005705A (es) | 2003-10-06 |
KR100827045B1 (ko) | 2008-05-02 |
AU2002233236B2 (en) | 2005-02-03 |
JP2004517110A (ja) | 2004-06-10 |
US20020127255A1 (en) | 2002-09-12 |
CN1484522A (zh) | 2004-03-24 |
CA2431391A1 (fr) | 2002-07-11 |
DE60124307D1 (de) | 2006-12-14 |
WO2002053122A3 (fr) | 2002-10-31 |
EP1349537B1 (fr) | 2006-11-02 |
EP1349537A2 (fr) | 2003-10-08 |
JP4451062B2 (ja) | 2010-04-14 |
WO2002053122A2 (fr) | 2002-07-11 |
US6565864B2 (en) | 2003-05-20 |
WO2002053122B1 (fr) | 2003-02-20 |
ATE344014T1 (de) | 2006-11-15 |
DE60124307T2 (de) | 2007-02-15 |
CN1287764C (zh) | 2006-12-06 |
KR20030074686A (ko) | 2003-09-19 |
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