ZA200208761B - Pharmaceutical form of administration for peptides, methods for its production and use. - Google Patents

Pharmaceutical form of administration for peptides, methods for its production and use.

Info

Publication number
ZA200208761B
ZA200208761B ZA200208761A ZA200208761A ZA200208761B ZA 200208761 B ZA200208761 B ZA 200208761B ZA 200208761 A ZA200208761 A ZA 200208761A ZA 200208761 A ZA200208761 A ZA 200208761A ZA 200208761 B ZA200208761 B ZA 200208761B
Authority
ZA
South Africa
Prior art keywords
peptides
administration
production
methods
pharmaceutical form
Prior art date
Application number
ZA200208761A
Other languages
English (en)
Inventor
Horst Bauer
Michael Damm
Werner Sarlikiotis
Original Assignee
Zentaris Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Zentaris Ag filed Critical Zentaris Ag
Publication of ZA200208761B publication Critical patent/ZA200208761B/xx

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/30Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
    • A61K47/36Polysaccharides; Derivatives thereof, e.g. gums, starch, alginate, dextrin, hyaluronic acid, chitosan, inulin, agar or pectin
    • A61K47/40Cyclodextrins; Derivatives thereof
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/08Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
    • A61K47/12Carboxylic acids; Salts or anhydrides thereof
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/26Carbohydrates, e.g. sugar alcohols, amino sugars, nucleic acids, mono-, di- or oligo-saccharides; Derivatives thereof, e.g. polysorbates, sorbitan fatty acid esters or glycyrrhizin
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/0012Galenical forms characterised by the site of application
    • A61K9/0019Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/08Solutions
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/14Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/19Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles lyophilised, i.e. freeze-dried, solutions or dispersions
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P13/00Drugs for disorders of the urinary system
    • A61P13/08Drugs for disorders of the urinary system of the prostate
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00Drugs for genital or sexual disorders; Contraceptives
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00Drugs for genital or sexual disorders; Contraceptives
    • A61P15/18Feminine contraceptives
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00Drugs for dermatological disorders
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • A61P35/04Antineoplastic agents specific for metastasis
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P5/00Drugs for disorders of the endocrine system
    • A61P5/24Drugs for disorders of the endocrine system of the sex hormones

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Epidemiology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Engineering & Computer Science (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • Dermatology (AREA)
  • Endocrinology (AREA)
  • Inorganic Chemistry (AREA)
  • Reproductive Health (AREA)
  • Biochemistry (AREA)
  • Molecular Biology (AREA)
  • Diabetes (AREA)
  • Urology & Nephrology (AREA)
  • Oncology (AREA)
  • Gynecology & Obstetrics (AREA)
  • Medicinal Preparation (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
ZA200208761A 2000-05-18 2002-10-30 Pharmaceutical form of administration for peptides, methods for its production and use. ZA200208761B (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE10024451A DE10024451A1 (de) 2000-05-18 2000-05-18 Pharmazeutische Darreichungsform für Peptide, Verfahren zu deren Herstellung und Verwendung

Publications (1)

Publication Number Publication Date
ZA200208761B true ZA200208761B (en) 2002-11-29

Family

ID=7642584

Family Applications (1)

Application Number Title Priority Date Filing Date
ZA200208761A ZA200208761B (en) 2000-05-18 2002-10-30 Pharmaceutical form of administration for peptides, methods for its production and use.

Country Status (25)

Country Link
US (2) US7718599B2 (fr)
EP (1) EP1282400B1 (fr)
JP (2) JP4944340B2 (fr)
KR (1) KR100580142B1 (fr)
CN (1) CN100342908C (fr)
AR (1) AR028588A1 (fr)
AU (1) AU777185B2 (fr)
BG (1) BG65976B1 (fr)
BR (1) BR0110892A (fr)
CA (1) CA2348167C (fr)
CZ (1) CZ303981B6 (fr)
DE (1) DE10024451A1 (fr)
HK (1) HK1058622A1 (fr)
HU (1) HUP0302050A3 (fr)
IL (1) IL152479A (fr)
MX (1) MXPA02011389A (fr)
NO (1) NO20025277L (fr)
NZ (1) NZ522381A (fr)
PL (1) PL203958B1 (fr)
RU (1) RU2253438C2 (fr)
SK (1) SK288118B6 (fr)
TW (1) TWI243059B (fr)
UA (1) UA74578C2 (fr)
WO (1) WO2001087265A2 (fr)
ZA (1) ZA200208761B (fr)

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US6828415B2 (en) * 1993-02-19 2004-12-07 Zentaris Gmbh Oligopeptide lyophilisate, their preparation and use
JP4940492B2 (ja) * 2000-09-04 2012-05-30 大正製薬株式会社 鉄化合物配合内服液剤
DE10157628A1 (de) * 2001-11-26 2003-06-12 Zentaris Ag Injektionslösung eines LHRH-Antagonisten
US7214662B2 (en) 2001-11-27 2007-05-08 Zentaris Gmbh Injectable solution of an LHRH antagonist
RS20050247A (en) * 2002-09-27 2007-06-04 Zentaris Gmbh., Administration form for pharmaceutically active peptides with sustained release and method for the production thereof
DE10332160A1 (de) 2003-07-15 2005-02-03 Röhm GmbH & Co. KG Multipartikuläre Arzneiform, enthaltend mucoadhaesiv formulierte Peptid- oder Protein-Wirkstoffe, sowie ein Verfahren zur Herstellung der Arzneiform
ATE381945T1 (de) * 2004-03-12 2008-01-15 Intercell Ag Verfahren zur solubilisierung von peptid- mischungen
EP1674082A1 (fr) * 2004-12-22 2006-06-28 Zentaris GmbH Procédé pour la manufacture des suspensions ou lyophilisates steriles des complexes mal-soluble de peptides basic, des formulations pharmaceutiques avec ces complexes et leur utilisation comme medicament
RU2358721C1 (ru) * 2005-04-15 2009-06-20 Виктор Павлович Кутняк Антинеопластический препарат (варианты)
WO2006110118A1 (fr) * 2005-04-15 2006-10-19 Victor Pavlovich Kutnyak Produit cytoprotecteur
BR112013013903A2 (pt) * 2010-12-06 2016-09-13 Astron Res Ltd preparação farmacêutica aquosa estável pronta para uso de cetrorelix para administração parenteral, processo para a fabricação de uma preparação farmacêutica aquosa estável pronta para uso de cetrorelix para uso de cetrorelix para administração parenteral
CN102144980B (zh) * 2011-03-07 2013-01-09 深圳市健元医药科技有限公司 一种更加稳定的lhrh拮抗剂冻干粉针剂
WO2015158823A1 (fr) * 2014-04-16 2015-10-22 Veyx-Pharma Gmbh Composition pharmaceutique vétérinaire et utilisation de ladite composition pharmaceutique vétérinaire
DK3576771T3 (da) * 2017-01-31 2022-05-30 Veru Inc Sammensætninger og fremgangsmåder til langvarig frigivelse af antagonister for gonadotropin-frigivende hormon (gnrh)
WO2020254952A1 (fr) * 2019-06-17 2020-12-24 Intas Pharmaceuticals Ltd. Formulation stable de cétrorélix
PL3811927T3 (pl) 2019-10-24 2022-02-07 Sun Pharmaceutical Industries Ltd Trwała pozajelitowa postać dawkowania octanu cetroreliksu
WO2022269572A1 (fr) 2021-06-25 2022-12-29 Extrovis Ag Compositions pharmaceutiques
WO2023017326A1 (fr) * 2021-08-11 2023-02-16 Rk Pharma Inc. Compositions prêtes à l'emploi d'acétate de cétrorélix

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JPS5892620A (ja) * 1981-11-28 1983-06-02 Sunstar Inc インタ−フエロン安定配合組成物
US4565804A (en) * 1984-09-07 1986-01-21 The Salk Institute For Biological Studies GnRH Antagonists VI
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US5643878A (en) * 1991-09-12 1997-07-01 Ciba-Geigy Corporation 5-amino-4-hydroxyhexanoic acid derivatives
JP3608802B2 (ja) * 1991-09-20 2005-01-12 第一サントリーファーマ株式会社 安定なカルシトニン医薬組成物及びその製造法
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US6828415B2 (en) * 1993-02-19 2004-12-07 Zentaris Gmbh Oligopeptide lyophilisate, their preparation and use
DE4305225A1 (de) * 1993-02-19 1994-08-25 Asta Medica Ag Neues Herstellverfahren für Cetrorelix Lyophilisat
JP3636480B2 (ja) * 1993-05-19 2005-04-06 科研製薬株式会社 凍結乾燥製剤
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Also Published As

Publication number Publication date
BR0110892A (pt) 2003-03-11
US20050159335A1 (en) 2005-07-21
JP4944340B2 (ja) 2012-05-30
AU7404101A (en) 2001-11-26
AU777185B2 (en) 2004-10-07
CN100342908C (zh) 2007-10-17
EP1282400A2 (fr) 2003-02-12
KR100580142B1 (ko) 2006-05-16
MXPA02011389A (es) 2003-04-25
SK288118B6 (sk) 2013-09-03
JP2003533466A (ja) 2003-11-11
RU2253438C2 (ru) 2005-06-10
TWI243059B (en) 2005-11-11
WO2001087265A3 (fr) 2002-04-18
UA74578C2 (uk) 2006-01-16
CZ20023969A3 (cs) 2003-05-14
HK1058622A1 (en) 2004-05-28
NO20025277D0 (no) 2002-11-04
BG107312A (bg) 2003-06-30
KR20030036179A (ko) 2003-05-09
NO20025277L (no) 2002-11-04
PL363007A1 (en) 2004-11-15
CA2348167C (fr) 2012-01-10
BG65976B1 (bg) 2010-08-31
WO2001087265A2 (fr) 2001-11-22
HUP0302050A2 (hu) 2003-09-29
AR028588A1 (es) 2003-05-14
EP1282400B1 (fr) 2016-12-14
PL203958B1 (pl) 2009-11-30
IL152479A (en) 2013-08-29
US7718599B2 (en) 2010-05-18
AU777185C (en) 2001-11-26
IL152479A0 (en) 2003-05-29
CZ303981B6 (cs) 2013-07-31
CA2348167A1 (fr) 2001-11-18
US20020039996A1 (en) 2002-04-04
US7696149B2 (en) 2010-04-13
CN1469734A (zh) 2004-01-21
NZ522381A (en) 2004-07-30
JP2011213733A (ja) 2011-10-27
DE10024451A1 (de) 2001-11-29
HUP0302050A3 (en) 2012-11-28
SK17162002A3 (sk) 2003-07-01

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