ZA200206888B - process for the preparation of 2-(4-alkyl-1-piperazinyl)-benzaldehyde and benzylidenyl compounds. - Google Patents

process for the preparation of 2-(4-alkyl-1-piperazinyl)-benzaldehyde and benzylidenyl compounds.

Info

Publication number
ZA200206888B
ZA200206888B ZA200206888A ZA200206888A ZA200206888B ZA 200206888 B ZA200206888 B ZA 200206888B ZA 200206888 A ZA200206888 A ZA 200206888A ZA 200206888 A ZA200206888 A ZA 200206888A ZA 200206888 B ZA200206888 B ZA 200206888B
Authority
ZA
South Africa
Prior art keywords
benzylidenyl
benzaldehyde
piperazinyl
alkyl
compounds
Prior art date
Application number
ZA200206888A
Other languages
English (en)
Inventor
Walinsky Stanley Walter
Sinay Jr Terry Gene
Rainville Joseph Philip
Original Assignee
Pfizer Prod Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Pfizer Prod Inc filed Critical Pfizer Prod Inc
Publication of ZA200206888B publication Critical patent/ZA200206888B/xx

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D241/00Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings
    • C07D241/02Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings not condensed with other rings
    • C07D241/04Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings not condensed with other rings having no double bonds between ring members or between ring members and non-ring members
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D295/00Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
    • C07D295/04Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms
    • C07D295/10Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by doubly bound oxygen or sulphur atoms
    • C07D295/112Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by doubly bound oxygen or sulphur atoms with the ring nitrogen atoms and the doubly bound oxygen or sulfur atoms separated by carbocyclic rings or by carbon chains interrupted by carbocyclic rings
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/24Antidepressants
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/30Drugs for disorders of the nervous system for treating abuse or dependence
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • A61P9/12Antihypertensives
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D279/00Heterocyclic compounds containing six-membered rings having one nitrogen atom and one sulfur atom as the only ring hetero atoms
    • C07D279/101,4-Thiazines; Hydrogenated 1,4-thiazines
    • C07D279/121,4-Thiazines; Hydrogenated 1,4-thiazines not condensed with other rings

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Engineering & Computer Science (AREA)
  • Biomedical Technology (AREA)
  • Neurosurgery (AREA)
  • Neurology (AREA)
  • Psychiatry (AREA)
  • Cardiology (AREA)
  • Addiction (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Pain & Pain Management (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
  • Nitrogen- Or Sulfur-Containing Heterocyclic Ring Compounds With Rings Of Six Or More Members (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
ZA200206888A 2001-08-30 2002-08-28 process for the preparation of 2-(4-alkyl-1-piperazinyl)-benzaldehyde and benzylidenyl compounds. ZA200206888B (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US31601001P 2001-08-30 2001-08-30

Publications (1)

Publication Number Publication Date
ZA200206888B true ZA200206888B (en) 2004-03-01

Family

ID=23227067

Family Applications (1)

Application Number Title Priority Date Filing Date
ZA200206888A ZA200206888B (en) 2001-08-30 2002-08-28 process for the preparation of 2-(4-alkyl-1-piperazinyl)-benzaldehyde and benzylidenyl compounds.

Country Status (24)

Country Link
US (1) US6608195B2 (xx)
EP (1) EP1288208B1 (xx)
JP (1) JP3902751B2 (xx)
KR (1) KR100503518B1 (xx)
CN (1) CN1172920C (xx)
AR (1) AR036373A1 (xx)
AT (1) ATE332897T1 (xx)
AU (1) AU2002300770B2 (xx)
BR (1) BR0203426A (xx)
CA (1) CA2399970A1 (xx)
CY (1) CY1106126T1 (xx)
DE (1) DE60213043T2 (xx)
DK (1) DK1288208T3 (xx)
ES (1) ES2266416T3 (xx)
HK (1) HK1051190A1 (xx)
HU (1) HUP0202907A3 (xx)
IL (1) IL151430A0 (xx)
MX (1) MXPA02008538A (xx)
PL (1) PL355799A1 (xx)
PT (1) PT1288208E (xx)
RU (1) RU2222533C1 (xx)
TW (1) TWI234563B (xx)
YU (1) YU62302A (xx)
ZA (1) ZA200206888B (xx)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20050165025A1 (en) * 2004-01-22 2005-07-28 Recordati Ireland Ltd. Combination therapy with 5HT 1A and 5HT 1B-receptor antagonists
WO2005113526A2 (en) * 2004-05-21 2005-12-01 Pfizer Products Inc. Metabolites of 4-(3,4-dichloro-phenyl)-2-[2-(4-methyl-piperazin-1-yl)-benzylidene]-thiomorpholin-3-one
CN111269585B (zh) * 2020-03-11 2021-10-08 苏州根岸生物科技有限责任公司 一种荧光染料及其制备方法与应用

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
UA56185C2 (uk) * 1996-09-30 2003-05-15 Пфайзер Інк. Аралкіл- та аралкіліденгетероциклічні лактами та іміди, фармацевтична композиція та спосіб лікування
US6248888B1 (en) * 1997-11-14 2001-06-19 Teva Pharmaceutical Industries Ltd. Process for the preparation of terazosin hydrochloride dihydrate
TW426667B (en) 1997-11-19 2001-03-21 Pfizer Piperidinylaminomethyl trifluoromethyl cyclic ether compounds as substance P antagonists

Also Published As

Publication number Publication date
EP1288208B1 (en) 2006-07-12
HU0202907D0 (xx) 2002-10-28
DE60213043D1 (de) 2006-08-24
AU2002300770B2 (en) 2007-06-07
HUP0202907A2 (hu) 2003-06-28
US20030087914A1 (en) 2003-05-08
CN1403448A (zh) 2003-03-19
CY1106126T1 (el) 2011-06-08
JP3902751B2 (ja) 2007-04-11
KR20030019190A (ko) 2003-03-06
PT1288208E (pt) 2006-09-29
US6608195B2 (en) 2003-08-19
RU2222533C1 (ru) 2004-01-27
HK1051190A1 (en) 2003-07-25
RU2002123289A (ru) 2004-03-10
PL355799A1 (en) 2003-03-10
EP1288208A1 (en) 2003-03-05
HUP0202907A3 (en) 2004-06-28
DK1288208T3 (da) 2006-10-16
DE60213043T2 (de) 2007-01-04
JP2003096060A (ja) 2003-04-03
KR100503518B1 (ko) 2005-07-25
MXPA02008538A (es) 2003-03-05
ES2266416T3 (es) 2007-03-01
CN1172920C (zh) 2004-10-27
YU62302A (sh) 2005-03-15
ATE332897T1 (de) 2006-08-15
TWI234563B (en) 2005-06-21
CA2399970A1 (en) 2003-02-28
BR0203426A (pt) 2003-05-13
AR036373A1 (es) 2004-09-01
IL151430A0 (en) 2003-04-10

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