ZA200204972B - Coating of implantable ophthalmic lenses to reduce edge glare. - Google Patents
Coating of implantable ophthalmic lenses to reduce edge glare. Download PDFInfo
- Publication number
- ZA200204972B ZA200204972B ZA200204972A ZA200204972A ZA200204972B ZA 200204972 B ZA200204972 B ZA 200204972B ZA 200204972 A ZA200204972 A ZA 200204972A ZA 200204972 A ZA200204972 A ZA 200204972A ZA 200204972 B ZA200204972 B ZA 200204972B
- Authority
- ZA
- South Africa
- Prior art keywords
- coating material
- hydrophilic polymer
- meth
- coating
- hydrophobic
- Prior art date
Links
- 238000000576 coating method Methods 0.000 title claims description 87
- 239000011248 coating agent Substances 0.000 title claims description 82
- 230000004313 glare Effects 0.000 title claims description 9
- 239000000463 material Substances 0.000 claims description 57
- 230000002209 hydrophobic effect Effects 0.000 claims description 36
- 229920001477 hydrophilic polymer Polymers 0.000 claims description 32
- 229920000058 polyacrylate Polymers 0.000 claims description 24
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 claims description 18
- 239000007943 implant Substances 0.000 claims description 17
- 229920000036 polyvinylpyrrolidone Polymers 0.000 claims description 14
- 238000000034 method Methods 0.000 claims description 13
- 235000013855 polyvinylpyrrolidone Nutrition 0.000 claims description 13
- 239000001267 polyvinylpyrrolidone Substances 0.000 claims description 13
- ILZXXGLGJZQLTR-UHFFFAOYSA-N 2-phenylethyl 2-methylprop-2-enoate Chemical compound CC(=C)C(=O)OCCC1=CC=CC=C1 ILZXXGLGJZQLTR-UHFFFAOYSA-N 0.000 claims description 8
- 239000000178 monomer Substances 0.000 claims description 8
- HPSGLFKWHYAKSF-UHFFFAOYSA-N 2-phenylethyl prop-2-enoate Chemical compound C=CC(=O)OCCC1=CC=CC=C1 HPSGLFKWHYAKSF-UHFFFAOYSA-N 0.000 claims description 6
- 239000004615 ingredient Substances 0.000 claims description 6
- 239000003795 chemical substances by application Substances 0.000 claims description 5
- 229920002338 polyhydroxyethylmethacrylate Polymers 0.000 claims description 5
- 125000003118 aryl group Chemical group 0.000 claims description 4
- 230000000903 blocking effect Effects 0.000 claims description 4
- 229910052760 oxygen Inorganic materials 0.000 claims description 4
- 229920002189 poly(glycerol 1-O-monomethacrylate) polymer Polymers 0.000 claims description 4
- 229920002401 polyacrylamide Polymers 0.000 claims description 4
- 239000003086 colorant Substances 0.000 claims description 3
- 239000006096 absorbing agent Substances 0.000 claims description 2
- 125000000956 methoxy group Chemical group [H]C([H])([H])O* 0.000 claims description 2
- OCBFFGCSTGGPSQ-UHFFFAOYSA-N [CH2]CC Chemical compound [CH2]CC OCBFFGCSTGGPSQ-UHFFFAOYSA-N 0.000 claims 2
- HNUALPPJLMYHDK-UHFFFAOYSA-N C[CH]C Chemical compound C[CH]C HNUALPPJLMYHDK-UHFFFAOYSA-N 0.000 claims 1
- 229920001577 copolymer Polymers 0.000 description 16
- OKKJLVBELUTLKV-UHFFFAOYSA-N Methanol Chemical compound OC OKKJLVBELUTLKV-UHFFFAOYSA-N 0.000 description 15
- NIXOWILDQLNWCW-UHFFFAOYSA-N acrylic acid group Chemical group C(C=C)(=O)O NIXOWILDQLNWCW-UHFFFAOYSA-N 0.000 description 13
- 239000003999 initiator Substances 0.000 description 9
- XNLICIUVMPYHGG-UHFFFAOYSA-N pentan-2-one Chemical compound CCCC(C)=O XNLICIUVMPYHGG-UHFFFAOYSA-N 0.000 description 9
- 239000002904 solvent Substances 0.000 description 9
- 239000000758 substrate Substances 0.000 description 6
- 239000007789 gas Substances 0.000 description 5
- 229920000642 polymer Polymers 0.000 description 5
- -1 2-pentanone Chemical class 0.000 description 4
- CSCPPACGZOOCGX-UHFFFAOYSA-N Acetone Chemical compound CC(C)=O CSCPPACGZOOCGX-UHFFFAOYSA-N 0.000 description 4
- 239000003431 cross linking reagent Substances 0.000 description 4
- 239000008367 deionised water Substances 0.000 description 4
- 239000010410 layer Substances 0.000 description 4
- 239000000203 mixture Substances 0.000 description 4
- 239000004743 Polypropylene Substances 0.000 description 3
- 239000008199 coating composition Substances 0.000 description 3
- 150000001875 compounds Chemical class 0.000 description 3
- 238000004132 cross linking Methods 0.000 description 3
- 239000012632 extractable Substances 0.000 description 3
- 230000036571 hydration Effects 0.000 description 3
- 238000006703 hydration reaction Methods 0.000 description 3
- 239000000017 hydrogel Substances 0.000 description 3
- 125000005395 methacrylic acid group Chemical group 0.000 description 3
- 239000003505 polymerization initiator Substances 0.000 description 3
- 229920001155 polypropylene Polymers 0.000 description 3
- 229920001296 polysiloxane Polymers 0.000 description 3
- 239000011877 solvent mixture Substances 0.000 description 3
- 229910021641 deionized water Inorganic materials 0.000 description 2
- 238000003618 dip coating Methods 0.000 description 2
- 238000001035 drying Methods 0.000 description 2
- 238000002513 implantation Methods 0.000 description 2
- 230000003287 optical effect Effects 0.000 description 2
- 229920003229 poly(methyl methacrylate) Polymers 0.000 description 2
- 239000004926 polymethyl methacrylate Substances 0.000 description 2
- DGVVWUTYPXICAM-UHFFFAOYSA-N β‐Mercaptoethanol Chemical compound OCCS DGVVWUTYPXICAM-UHFFFAOYSA-N 0.000 description 2
- HJIAMFHSAAEUKR-UHFFFAOYSA-N (2-hydroxyphenyl)-phenylmethanone Chemical class OC1=CC=CC=C1C(=O)C1=CC=CC=C1 HJIAMFHSAAEUKR-UHFFFAOYSA-N 0.000 description 1
- NOBYOEQUFMGXBP-UHFFFAOYSA-N (4-tert-butylcyclohexyl) (4-tert-butylcyclohexyl)oxycarbonyloxy carbonate Chemical compound C1CC(C(C)(C)C)CCC1OC(=O)OOC(=O)OC1CCC(C(C)(C)C)CC1 NOBYOEQUFMGXBP-UHFFFAOYSA-N 0.000 description 1
- BQZJOQXSCSZQPS-UHFFFAOYSA-N 2-methoxy-1,2-diphenylethanone Chemical compound C=1C=CC=CC=1C(OC)C(=O)C1=CC=CC=C1 BQZJOQXSCSZQPS-UHFFFAOYSA-N 0.000 description 1
- RIWRBSMFKVOJMN-UHFFFAOYSA-N 2-methyl-1-phenylpropan-2-ol Chemical compound CC(C)(O)CC1=CC=CC=C1 RIWRBSMFKVOJMN-UHFFFAOYSA-N 0.000 description 1
- JHWGFJBTMHEZME-UHFFFAOYSA-N 4-prop-2-enoyloxybutyl prop-2-enoate Chemical compound C=CC(=O)OCCCCOC(=O)C=C JHWGFJBTMHEZME-UHFFFAOYSA-N 0.000 description 1
- NIXOWILDQLNWCW-UHFFFAOYSA-M Acrylate Chemical compound [O-]C(=O)C=C NIXOWILDQLNWCW-UHFFFAOYSA-M 0.000 description 1
- VEXZGXHMUGYJMC-UHFFFAOYSA-M Chloride anion Chemical compound [Cl-] VEXZGXHMUGYJMC-UHFFFAOYSA-M 0.000 description 1
- MYMOFIZGZYHOMD-UHFFFAOYSA-N Dioxygen Chemical compound O=O MYMOFIZGZYHOMD-UHFFFAOYSA-N 0.000 description 1
- WHNWPMSKXPGLAX-UHFFFAOYSA-N N-Vinyl-2-pyrrolidone Chemical compound C=CN1CCCC1=O WHNWPMSKXPGLAX-UHFFFAOYSA-N 0.000 description 1
- HLJYBXJFKDDIBI-UHFFFAOYSA-N O=[PH2]C(=O)C1=CC=CC=C1 Chemical compound O=[PH2]C(=O)C1=CC=CC=C1 HLJYBXJFKDDIBI-UHFFFAOYSA-N 0.000 description 1
- HWRUXTKGWGXAGU-UHFFFAOYSA-N [3-(4-hydroxybenzotriazol-2-yl)phenyl] prop-2-enoate Chemical class OC1=CC=CC2=NN(N=C21)C1=CC=CC(=C1)OC(C=C)=O HWRUXTKGWGXAGU-UHFFFAOYSA-N 0.000 description 1
- 229920006243 acrylic copolymer Polymers 0.000 description 1
- 238000007605 air drying Methods 0.000 description 1
- 150000001298 alcohols Chemical class 0.000 description 1
- 125000001931 aliphatic group Chemical group 0.000 description 1
- QVGXLLKOCUKJST-UHFFFAOYSA-N atomic oxygen Chemical compound [O] QVGXLLKOCUKJST-UHFFFAOYSA-N 0.000 description 1
- QRUDEWIWKLJBPS-UHFFFAOYSA-N benzotriazole Chemical compound C1=CC=C2N[N][N]C2=C1 QRUDEWIWKLJBPS-UHFFFAOYSA-N 0.000 description 1
- 239000012964 benzotriazole Substances 0.000 description 1
- 238000005266 casting Methods 0.000 description 1
- 239000011247 coating layer Substances 0.000 description 1
- 230000000052 comparative effect Effects 0.000 description 1
- 238000007796 conventional method Methods 0.000 description 1
- 230000003292 diminished effect Effects 0.000 description 1
- 229910001882 dioxygen Inorganic materials 0.000 description 1
- 238000009826 distribution Methods 0.000 description 1
- WNAHIZMDSQCWRP-UHFFFAOYSA-N dodecane-1-thiol Chemical compound CCCCCCCCCCCCS WNAHIZMDSQCWRP-UHFFFAOYSA-N 0.000 description 1
- 238000002474 experimental method Methods 0.000 description 1
- 238000000605 extraction Methods 0.000 description 1
- 230000004907 flux Effects 0.000 description 1
- 125000000524 functional group Chemical group 0.000 description 1
- 230000000887 hydrating effect Effects 0.000 description 1
- 230000004410 intraocular pressure Effects 0.000 description 1
- 150000002576 ketones Chemical class 0.000 description 1
- 125000000325 methylidene group Chemical group [H]C([H])=* 0.000 description 1
- 230000006855 networking Effects 0.000 description 1
- 239000000382 optic material Substances 0.000 description 1
- 239000003960 organic solvent Substances 0.000 description 1
- 230000001590 oxidative effect Effects 0.000 description 1
- 239000001301 oxygen Substances 0.000 description 1
- 239000002798 polar solvent Substances 0.000 description 1
- 229920002959 polymer blend Polymers 0.000 description 1
- 238000002360 preparation method Methods 0.000 description 1
- HNJBEVLQSNELDL-UHFFFAOYSA-N pyrrolidin-2-one Chemical compound O=C1CCCN1 HNJBEVLQSNELDL-UHFFFAOYSA-N 0.000 description 1
- 210000001525 retina Anatomy 0.000 description 1
- 238000004528 spin coating Methods 0.000 description 1
- 230000008961 swelling Effects 0.000 description 1
- 238000009281 ultraviolet germicidal irradiation Methods 0.000 description 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
- A61L27/28—Materials for coating prostheses
- A61L27/34—Macromolecular materials
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
- A61F2/00—Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
- A61F2/02—Prostheses implantable into the body
- A61F2/14—Eye parts, e.g. lenses, corneal implants; Implanting instruments specially adapted therefor; Artificial eyes
- A61F2/16—Intraocular lenses
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
- A61F2/00—Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
- A61F2/02—Prostheses implantable into the body
- A61F2/14—Eye parts, e.g. lenses, corneal implants; Implanting instruments specially adapted therefor; Artificial eyes
- A61F2/16—Intraocular lenses
- A61F2002/1696—Having structure for blocking or reducing amount of light transmitted, e.g. glare reduction
Landscapes
- Health & Medical Sciences (AREA)
- Public Health (AREA)
- Animal Behavior & Ethology (AREA)
- Veterinary Medicine (AREA)
- Oral & Maxillofacial Surgery (AREA)
- Transplantation (AREA)
- General Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Medicinal Chemistry (AREA)
- Epidemiology (AREA)
- Chemical & Material Sciences (AREA)
- Ophthalmology & Optometry (AREA)
- Dermatology (AREA)
- Biomedical Technology (AREA)
- Engineering & Computer Science (AREA)
- Cardiology (AREA)
- Heart & Thoracic Surgery (AREA)
- Vascular Medicine (AREA)
- Materials For Medical Uses (AREA)
- Prostheses (AREA)
- Eyeglasses (AREA)
- Application Of Or Painting With Fluid Materials (AREA)
- Coating Of Shaped Articles Made Of Macromolecular Substances (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US17577900P | 2000-01-12 | 2000-01-12 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ZA200204972B true ZA200204972B (en) | 2003-06-20 |
Family
ID=22641583
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ZA200204972A ZA200204972B (en) | 2000-01-12 | 2002-06-20 | Coating of implantable ophthalmic lenses to reduce edge glare. |
Country Status (14)
| Country | Link |
|---|---|
| EP (1) | EP1246652A1 (es) |
| JP (1) | JP2003519538A (es) |
| KR (1) | KR20020062357A (es) |
| CN (1) | CN1423570A (es) |
| AR (1) | AR034844A1 (es) |
| AU (1) | AU768090B2 (es) |
| BR (1) | BR0016998A (es) |
| CA (1) | CA2392593A1 (es) |
| HK (1) | HK1048957A1 (es) |
| MX (1) | MXPA02006841A (es) |
| NO (1) | NO20023343L (es) |
| NZ (1) | NZ520117A (es) |
| WO (1) | WO2001051103A1 (es) |
| ZA (1) | ZA200204972B (es) |
Families Citing this family (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| ATE514491T1 (de) | 2004-11-29 | 2011-07-15 | Dsm Ip Assets Bv | Verfahren zur verringerung der menge von migrierbaren komponenten von polymerbeschichtungen |
| US8871869B2 (en) | 2005-12-09 | 2014-10-28 | Dsm Ip Assets B.V. | Hydrophilic coating |
| WO2008031595A2 (en) | 2006-09-13 | 2008-03-20 | Dsm Ip Assets B.V. | Coated medical device |
| DK2114477T3 (da) | 2007-02-28 | 2012-08-20 | Dsm Ip Assets Bv | Hydrofil coating |
| WO2008104573A2 (en) | 2007-02-28 | 2008-09-04 | Dsm Ip Assets B.V. | Hydrophilic coating |
| CN102947376B (zh) | 2010-06-16 | 2015-04-29 | 帝斯曼知识产权资产管理有限公司 | 用于制备亲水性涂层的涂料配制品 |
| US20130178935A1 (en) * | 2012-01-11 | 2013-07-11 | Lara Henry | Polarized component ocular devices |
| CN109124826A (zh) * | 2017-06-28 | 2019-01-04 | 爱博诺德（北京）医疗科技有限公司 | 眼科透镜 |
Family Cites Families (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5755786A (en) * | 1992-09-28 | 1998-05-26 | Iolab Corporation | Ophthalmic lens with reduced edge glare |
| EP0774983B1 (en) * | 1995-06-07 | 2002-12-04 | Alcon Laboratories, Inc. | Improved high refractive index ophthalmic lens materials |
| US5698192A (en) * | 1996-09-25 | 1997-12-16 | University Of Florida | Ocular implants and methods for their manufacture |
| US6169127B1 (en) * | 1996-08-30 | 2001-01-02 | Novartis Ag | Plasma-induced polymer coatings |
| EP1001720B1 (en) * | 1997-08-07 | 2002-10-02 | Alcon Laboratories, Inc. | Intracorneal diffractive lens |
-
2000
- 2000-12-06 WO PCT/US2000/033102 patent/WO2001051103A1/en active IP Right Grant
- 2000-12-06 JP JP2001551524A patent/JP2003519538A/ja not_active Withdrawn
- 2000-12-06 AU AU25758/01A patent/AU768090B2/en not_active Ceased
- 2000-12-06 NZ NZ520117A patent/NZ520117A/xx unknown
- 2000-12-06 KR KR1020027007899A patent/KR20020062357A/ko not_active Application Discontinuation
- 2000-12-06 CN CN00818360A patent/CN1423570A/zh active Pending
- 2000-12-06 EP EP00989222A patent/EP1246652A1/en not_active Withdrawn
- 2000-12-06 BR BR0016998-6A patent/BR0016998A/pt not_active Application Discontinuation
- 2000-12-06 MX MXPA02006841A patent/MXPA02006841A/es unknown
- 2000-12-06 CA CA002392593A patent/CA2392593A1/en not_active Abandoned
-
2001
- 2001-01-08 AR ARP010100072A patent/AR034844A1/es unknown
-
2002
- 2002-06-20 ZA ZA200204972A patent/ZA200204972B/en unknown
- 2002-07-11 NO NO20023343A patent/NO20023343L/no not_active Application Discontinuation
-
2003
- 2003-01-29 HK HK03100727.7A patent/HK1048957A1/zh unknown
Also Published As
| Publication number | Publication date |
|---|---|
| MXPA02006841A (es) | 2003-05-23 |
| CN1423570A (zh) | 2003-06-11 |
| WO2001051103A1 (en) | 2001-07-19 |
| EP1246652A1 (en) | 2002-10-09 |
| BR0016998A (pt) | 2002-10-15 |
| NZ520117A (en) | 2003-02-28 |
| NO20023343D0 (no) | 2002-07-11 |
| AR034844A1 (es) | 2004-03-24 |
| JP2003519538A (ja) | 2003-06-24 |
| NO20023343L (no) | 2002-09-09 |
| AU2575801A (en) | 2001-07-24 |
| KR20020062357A (ko) | 2002-07-25 |
| CA2392593A1 (en) | 2001-07-19 |
| HK1048957A1 (zh) | 2003-04-25 |
| AU768090B2 (en) | 2003-12-04 |
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