ZA200203799B - Antithrombotic compound. - Google Patents

Antithrombotic compound.

Info

Publication number
ZA200203799B
ZA200203799B ZA200203799A ZA200203799A ZA200203799B ZA 200203799 B ZA200203799 B ZA 200203799B ZA 200203799 A ZA200203799 A ZA 200203799A ZA 200203799 A ZA200203799 A ZA 200203799A ZA 200203799 B ZA200203799 B ZA 200203799B
Authority
ZA
South Africa
Prior art keywords
antithrombotic compound
antithrombotic
compound
Prior art date
Application number
ZA200203799A
Other languages
English (en)
Inventor
Constant Adriaan Anton Boeckel
Tamara Theodora Maria Geertsen
Cornelia Maria Tromp
Original Assignee
Akzo Nobel Nv
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Akzo Nobel Nv filed Critical Akzo Nobel Nv
Publication of ZA200203799B publication Critical patent/ZA200203799B/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H3/00—Compounds containing only hydrogen atoms and saccharide radicals having only carbon, hydrogen, and oxygen atoms
    • C07H3/06—Oligosaccharides, i.e. having three to five saccharide radicals attached to each other by glycosidic linkages
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/70—Carbohydrates; Sugars; Derivatives thereof
    • A61K31/7042—Compounds having saccharide radicals and heterocyclic rings
    • A61K31/7052—Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides
    • A61K31/706—Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides containing six-membered rings with nitrogen as a ring hetero atom
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A61P7/02—Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H1/00—Processes for the preparation of sugar derivatives
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H15/00—Compounds containing hydrocarbon or substituted hydrocarbon radicals directly attached to hetero atoms of saccharide radicals
    • C07H15/26—Acyclic or carbocyclic radicals, substituted by hetero rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K9/00—Peptides having up to 20 amino acids, containing saccharide radicals and having a fully defined sequence; Derivatives thereof
    • C07K9/001—Peptides having up to 20 amino acids, containing saccharide radicals and having a fully defined sequence; Derivatives thereof the peptide sequence having less than 12 amino acids and not being part of a ring structure
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
ZA200203799A 1999-12-07 2002-05-13 Antithrombotic compound. ZA200203799B (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
EP99204172 1999-12-07

Publications (1)

Publication Number Publication Date
ZA200203799B true ZA200203799B (en) 2003-10-29

Family

ID=8240976

Family Applications (1)

Application Number Title Priority Date Filing Date
ZA200203799A ZA200203799B (en) 1999-12-07 2002-05-13 Antithrombotic compound.

Country Status (23)

Country Link
US (1) US6875755B2 (ru)
EP (1) EP1237897B1 (ru)
JP (1) JP4820517B2 (ru)
KR (1) KR100776607B1 (ru)
CN (1) CN1195767C (ru)
AR (1) AR026726A1 (ru)
AU (1) AU781846B2 (ru)
BR (1) BR0016217A (ru)
CA (1) CA2393042C (ru)
CO (1) CO5251449A1 (ru)
CZ (1) CZ303385B6 (ru)
HK (1) HK1047593A1 (ru)
HU (1) HUP0203471A3 (ru)
IL (2) IL149628A0 (ru)
NO (1) NO323059B1 (ru)
NZ (1) NZ519100A (ru)
PE (1) PE20010935A1 (ru)
PL (1) PL202840B1 (ru)
RU (1) RU2266913C2 (ru)
SK (1) SK287682B6 (ru)
TW (1) TWI289566B (ru)
WO (1) WO2001042262A2 (ru)
ZA (1) ZA200203799B (ru)

Families Citing this family (16)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA2806561C (en) * 2001-09-07 2015-12-22 Alchemia Limited Synthetic heparin pentasaccharides
WO2004007468A1 (en) 2002-07-15 2004-01-22 Merck & Co., Inc. Piperidino pyrimidine dipeptidyl peptidase inhibitors for the treatment of diabetes
US7390809B2 (en) 2002-10-07 2008-06-24 Merck & Co., Inc. Beta-amino heterocyclic dipeptidyl peptidase inhibitors for diabetes
EP1562925B1 (en) 2002-11-07 2007-01-03 Merck & Co., Inc. Phenylalanine derivatives as dipeptidyl peptidase inhibitors for the treatment or prevention of diabetes
CA2512546A1 (en) 2003-01-17 2004-08-05 Merck & Co., Inc. 3-amino-4-phenylbutanoic acid derivatives as dipeptidyl peptidase inhibitors for the treatment or prevention of diabetes
AU2004210149A1 (en) 2003-01-31 2004-08-19 Merck & Co., Inc. 3-amino-4-phenylbutanoic acid derivatives as dipeptidyl peptidase inhibitors for the treatment or prevention of diabetes
WO2004103276A2 (en) 2003-05-14 2004-12-02 Merck & Co., Inc. 3-amino-4-phenylbutanoic acid derivatives as dipeptidyl peptidase inhibitors for the treatment or prevention of diabetes
ATE463492T1 (de) 2003-06-06 2010-04-15 Merck Sharp & Dohme Kondensierte indole als dipeptidyl-peptidase- hemmer zur behandlung oder prävention von diabetes
EP1638950A4 (en) 2003-06-17 2010-06-30 Merck Sharp & Dohme CYCLOHEXYLGLYCIN DERIVATIVES AS INHIBITORS OF DIPEPTIDYL PEPTIDASE FOR THE TREATMENT OR PREVENTION OF DIABETES
US7259160B2 (en) 2003-07-31 2007-08-21 Merck & Co., Inc. Hexahydrodiazepinones as dipeptidyl peptidase-IV inhibitors for the treatment or prevention of diabetes
EP1574516A1 (en) 2004-03-05 2005-09-14 Sanofi-Aventis Antithrombotic compound
TW200621794A (en) * 2004-10-06 2006-07-01 Akzo Nobel Nv Pulmonary administration of an antithrombotic compound
TWI403334B (zh) * 2004-12-23 2013-08-01 Merck Sharp & Dohme 包含生物素殘基之抗血栓雙重抑制劑
TWI376234B (en) 2005-02-01 2012-11-11 Msd Oss Bv Conjugates of a polypeptide and an oligosaccharide
AU2006301331B2 (en) * 2005-10-10 2011-12-22 Merck Sharp & Dohme B.V. Anticoagulant antithrombotic dual inhibitors comprising a biotin label
JP6109574B2 (ja) 2009-12-18 2017-04-05 カタラン、フランス、バインハイム、ソシエテ、アノニムＣａｔａｌｅｎｔ Ｆｒａｎｃｅ Ｂｅｉｎｈｅｉｍ Ｓａ 合成オリゴサッカリドを含有する医薬経口剤形

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE4115468A1 (de) * 1991-05-11 1992-11-12 Behringwerke Ag Amidinophenylalaninderivate, verfahren zu deren herstellung, deren verwendung und diese enthaltende mittel als antikoagulantien
DE4206858A1 (de) * 1992-03-05 1993-09-09 Behringwerke Ag Glycopeptid-derivate, verfahren zu ihrer herstellung und diese verbindungen enthaltende pharmazeutische mittel
DK0649854T3 (da) * 1993-09-01 2000-07-03 Akzo Nobel Nv Biskonjugater omfattende to saccharider og en spacer
IL126893A (en) * 1997-11-19 2003-05-29 Akzo Nobel Nv Sulfated pentasaccharide derivatives and pharmaceutical compositions containing them
NZ508623A (en) * 1998-06-17 2002-11-26 Akzo Nobel Nv Antithrombotic peptide compounds with saccharide radicals

Also Published As

Publication number Publication date
KR20020070988A (ko) 2002-09-11
US6875755B2 (en) 2005-04-05
CZ20021958A3 (cs) 2002-08-14
AR026726A1 (es) 2003-02-26
RU2266913C2 (ru) 2005-12-27
NO20022689D0 (no) 2002-06-06
JP2003520208A (ja) 2003-07-02
CZ303385B6 (cs) 2012-08-29
JP4820517B2 (ja) 2011-11-24
HK1047593A1 (zh) 2003-02-28
CA2393042A1 (en) 2001-06-14
EP1237897A2 (en) 2002-09-11
PL355484A1 (en) 2004-05-04
WO2001042262A2 (en) 2001-06-14
HUP0203471A2 (hu) 2003-02-28
NO323059B1 (no) 2006-12-27
AU781846B2 (en) 2005-06-16
CN1407989A (zh) 2003-04-02
NO20022689L (no) 2002-06-06
BR0016217A (pt) 2002-09-10
IL149628A0 (en) 2002-11-10
AU2003801A (en) 2001-06-18
CO5251449A1 (es) 2003-02-28
IL149628A (en) 2010-04-29
CN1195767C (zh) 2005-04-06
SK7942002A3 (en) 2002-09-10
TWI289566B (en) 2007-11-11
KR100776607B1 (ko) 2007-11-16
NZ519100A (en) 2004-09-24
CA2393042C (en) 2011-06-28
SK287682B6 (sk) 2011-06-06
PE20010935A1 (es) 2001-09-20
US20030114361A1 (en) 2003-06-19
WO2001042262A3 (en) 2001-12-13
HUP0203471A3 (en) 2003-03-28
PL202840B1 (pl) 2009-07-31
EP1237897B1 (en) 2015-01-14

Similar Documents

Publication Publication Date Title
MXPA01013362A (es) Anticuerpos de humano, anti-alfavbeta3 recombinantes, °cidos nucleicos que codifican a los mismos y metodos de uso.
EG24814A (en) Novel compounds.
ZA200200477B (en) 2-pyrazolin-5-ones.
EG24361A (en) 4-pyrimiding1-n-acy1.l.phenlalanines
ZA200202537B (en) Pour-on-formulations.
ZA200201829B (en) New phenylpiperazines.
HK1053470A1 (en) 4-Pyridinyln-acyl-l-phenylalanines.
ZA200006352B (en) Compound napkin.
ZA200108968B (en) New compounds.
HK1029502A1 (en) Slider-pull-assembling unit.
ZA200203799B (en) Antithrombotic compound.
ZA984088B (en) Antithrombotic compound.
GB9924797D0 (en) Compound
ZA200001416B (en) Pesticidal compositions.
ZA992899B (en) Novel compound.
MXPA02000261A (es) Aminoindanos novedosos.
GB0029720D0 (en) I.S machine7544232001
GB9921928D0 (en) Compound
GB9914342D0 (en) Compound
GB0031563D0 (en) Compound
GB0031557D0 (en) Compound
ZA200204581B (en) Nitro-sulfobenzamides.
GB9921929D0 (en) Compound
GB9929255D0 (en) Compound
ZA200201714B (en) Novel compound F-15078.