ZA200202181B - Agonists specific for the peripheral cannabinoid receptor. - Google Patents
Agonists specific for the peripheral cannabinoid receptor.Info
- Publication number
- ZA200202181B ZA200202181B ZA200202181A ZA200202181A ZA200202181B ZA 200202181 B ZA200202181 B ZA 200202181B ZA 200202181 A ZA200202181 A ZA 200202181A ZA 200202181 A ZA200202181 A ZA 200202181A ZA 200202181 B ZA200202181 B ZA 200202181B
- Authority
- ZA
- South Africa
- Prior art keywords
- compounds
- activity
- specific
- peripheral
- peripheral cannabinoid
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/21—Esters, e.g. nitroglycerine, selenocyanates
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/21—Esters, e.g. nitroglycerine, selenocyanates
- A61K31/215—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids
- A61K31/216—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids of acids having aromatic rings, e.g. benactizyne, clofibrate
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/075—Ethers or acetals
- A61K31/085—Ethers or acetals having an ether linkage to aromatic ring nuclear carbon
- A61K31/09—Ethers or acetals having an ether linkage to aromatic ring nuclear carbon having two or more such linkages
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/02—Drugs for disorders of the nervous system for peripheral neuropathies
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
- A61P37/06—Immunosuppressants, e.g. drugs for graft rejection
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/12—Antihypertensives
Landscapes
- Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Chemical & Material Sciences (AREA)
- Veterinary Medicine (AREA)
- Medicinal Chemistry (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Epidemiology (AREA)
- Immunology (AREA)
- Emergency Medicine (AREA)
- Neurology (AREA)
- Pain & Pain Management (AREA)
- Rheumatology (AREA)
- Biomedical Technology (AREA)
- Heart & Thoracic Surgery (AREA)
- Neurosurgery (AREA)
- Cardiology (AREA)
- Transplantation (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Medicines Containing Plant Substances (AREA)
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
IL132661A IL132661A (en) | 1999-10-31 | 1999-10-31 | Agonists specific for peripheral cannabinoid receptors |
Publications (1)
Publication Number | Publication Date |
---|---|
ZA200202181B true ZA200202181B (en) | 2003-05-28 |
Family
ID=11073405
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
ZA200202181A ZA200202181B (en) | 1999-10-31 | 2002-03-18 | Agonists specific for the peripheral cannabinoid receptor. |
Country Status (13)
Country | Link |
---|---|
US (3) | US6864291B1 (xx) |
EP (1) | EP1244440B1 (xx) |
JP (1) | JP4231906B2 (xx) |
KR (1) | KR100770695B1 (xx) |
AT (1) | ATE286389T1 (xx) |
AU (1) | AU778149B2 (xx) |
CA (1) | CA2385928A1 (xx) |
DE (1) | DE60017287T2 (xx) |
HU (1) | HUP0203681A3 (xx) |
IL (2) | IL132661A (xx) |
NZ (1) | NZ518054A (xx) |
WO (1) | WO2001032169A1 (xx) |
ZA (1) | ZA200202181B (xx) |
Families Citing this family (45)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US6342611B1 (en) * | 1997-10-10 | 2002-01-29 | Cytovia, Inc. | Fluorogenic or fluorescent reporter molecules and their applications for whole-cell fluorescence screening assays for capsases and other enzymes and the use thereof |
EP1075470B1 (en) * | 1998-05-04 | 2003-08-13 | The University Of Connecticut | Novel analgesic and immunomodulatory cannabinoids |
US7589220B2 (en) * | 1998-06-09 | 2009-09-15 | University Of Connecticut | Inhibitors of the anandamide transporter |
US7897598B2 (en) * | 1998-06-09 | 2011-03-01 | Alexandros Makriyannis | Inhibitors of the anandamide transporter |
US7276613B1 (en) | 1998-11-24 | 2007-10-02 | University Of Connecticut | Retro-anandamides, high affinity and stability cannabinoid receptor ligands |
US7161016B1 (en) | 1998-11-24 | 2007-01-09 | University Of Connecticut | Cannabimimetic lipid amides as useful medications |
US7393842B2 (en) * | 2001-08-31 | 2008-07-01 | University Of Connecticut | Pyrazole analogs acting on cannabinoid receptors |
US7119108B1 (en) | 1999-10-18 | 2006-10-10 | University Of Connecticut | Pyrazole derivatives as cannabinoid receptor antagonists |
US7741365B2 (en) * | 1999-10-18 | 2010-06-22 | University Of Connecticut | Peripheral cannabinoid receptor (CB2) selective ligands |
US8084467B2 (en) * | 1999-10-18 | 2011-12-27 | University Of Connecticut | Pyrazole derivatives as cannabinoid receptor antagonists |
US6900236B1 (en) | 1999-10-18 | 2005-05-31 | University Of Connecticut | Cannabimimetic indole derivatives |
US6943266B1 (en) * | 1999-10-18 | 2005-09-13 | University Of Connecticut | Bicyclic cannabinoid agonists for the cannabinoid receptor |
AU778159B2 (en) | 1999-10-18 | 2004-11-18 | University Of Connecticut, The | Peripheral cannabinoid receptor (CB2) selective ligands |
IL132661A (en) * | 1999-10-31 | 2008-11-26 | Raphael Mechoulam | Agonists specific for peripheral cannabinoid receptors |
WO2002058636A2 (en) * | 2001-01-26 | 2002-08-01 | University Of Connecticut | Novel cannabimimetic ligands |
JP2005503998A (ja) * | 2001-01-29 | 2005-02-10 | ユニバーシティ オブ コネチカット | 受容体選択性のカンナビミメティックアミノアルキルインドール |
JP4312594B2 (ja) * | 2001-07-13 | 2009-08-12 | ユニバーシティ オブ コネチカット | 新規な二環式及び三環式カンナビノイド |
CN1589269A (zh) | 2001-10-26 | 2005-03-02 | 康涅狄格大学 | 杂1,2-二氢化茚:一类新型有效的大麻配体 |
TW200407110A (en) | 2001-11-23 | 2004-05-16 | Astrazeneca Ab | New use for the treatment of gastroesophageal reflux disease |
WO2003061699A1 (fr) * | 2001-12-27 | 2003-07-31 | Japan Tobacco, Inc. | Remedes pour affections allergiques |
JP2005523259A (ja) * | 2002-01-31 | 2005-08-04 | ファーモス コーポレイション | 二環式cb2カンナビノイド受容体リガンド |
IL150302A (en) * | 2002-01-31 | 2008-07-08 | Naim Menashe | Bicyclic cb2 cannabinoid receptor ligands |
WO2004017922A2 (en) | 2002-08-23 | 2004-03-04 | University Of Connecticut | Keto cannabinoids with therapeutic indications |
EP1606019A1 (en) * | 2003-03-07 | 2005-12-21 | The University Court of The University of Aberdeen | Cannabinoid receptor inverse agonists and neutral antagonists as therapeutic agents for the treatment of bone disorders |
AR043633A1 (es) | 2003-03-20 | 2005-08-03 | Schering Corp | Ligandos de receptores de canabinoides |
CN1809552A (zh) * | 2003-05-20 | 2006-07-26 | 田纳西大学研究基金会 | 大麻素衍生物、其制备方法和用途 |
EP1758566A2 (en) * | 2004-06-22 | 2007-03-07 | Pharmos Limited | Use of cb2 receptors agonists for the treatment of huntington"s disease |
TWI366460B (en) | 2005-06-16 | 2012-06-21 | Euro Celtique Sa | Cannabinoid active pharmaceutical ingredient for improved dosage forms |
US20070060638A1 (en) * | 2005-08-26 | 2007-03-15 | Olmstead Mary C | Methods and therapies for potentiating therapeutic activities of a cannabinoid receptor agonist via administration of a cannabinoid receptor antagonist |
KR20090007606A (ko) * | 2006-04-27 | 2009-01-19 | 솔베이 파머슈티컬스 게엠베하 | CBx 칸나비노이드 수용체 조절제들 및 칼륨 채널 조절제들을 포함하는 약학적 조성물들 |
US7763607B2 (en) | 2006-04-27 | 2010-07-27 | Solvay Pharmaceuticals Gmbh | Pharmaceutical compositions comprising CBx cannabinoid receptor modulators and potassium channel modulators |
US20100004244A1 (en) * | 2006-06-27 | 2010-01-07 | Yissum Research Development Company Of The Hebrew University Of Jerusalem | Use of cb2 receptor agonists for promoting neurogenesis |
US9763894B2 (en) * | 2006-12-05 | 2017-09-19 | Virginia Commonwealth University | Inflammation therapy |
GB0702862D0 (en) * | 2007-02-14 | 2007-03-28 | Univ Aberdeen | Therapeutic compounds |
WO2008107879A1 (en) * | 2007-03-05 | 2008-09-12 | Yissum Research Development Company Of The Hebrew University Of Jerusalem | Novel cannabidiol derivatives and their use as anti-inflammatory agents |
WO2009044402A1 (en) | 2007-10-02 | 2009-04-09 | Ariel - University Research And Development Company Ltd. | Endocannabinoids for enhancing growth and development in infants |
US9193713B2 (en) | 2007-10-12 | 2015-11-24 | Abbvie Inc. | Compounds as cannabinoid receptor ligands |
EP2346804B1 (en) | 2008-10-06 | 2017-03-08 | Yissum Research Development Company of the Hebrew University of Jerusalem, Ltd. | Composition comprising cb receptor agonists and uses thereof |
US20120277296A1 (en) | 2009-07-23 | 2012-11-01 | Sophie Lotersztajn | Selective CB2 Receptor Agonists for Use in the Prevention or Treatment of Alcoholic Liver Disease |
ITMI20122221A1 (it) | 2012-12-21 | 2014-06-22 | C4T S C A R L | Nuovi composti del 2,3-diidro-4h-1,3-benzossazin-4-one, metodo per prepararli e forma farmaceutica che li comprende |
US9486419B2 (en) | 2013-04-17 | 2016-11-08 | Ariel-University Research And Development Company | CB2 receptor ligands for the treatment of psychiatric disorders |
EP2992880A1 (en) * | 2014-09-04 | 2016-03-09 | Fundació Institut de Recerca de l'Hospital de la Santa Creu l Sant Pau | Use of heme oxygenase 1 inducers and cannabinoid 2 receptor or delta-opioid receptor agonists in inflammatory pain |
US9585867B2 (en) | 2015-08-06 | 2017-03-07 | Charles Everett Ankner | Cannabinod formulation for the sedation of a human or animal |
WO2019030762A2 (en) | 2017-08-09 | 2019-02-14 | Stahl Veronica | CANNABIS AND ITS DERIVATIVES FOR THE TREATMENT OF PAIN RELATED TO PAIN AND BONE REGENERATION ASSOCIATED WITH BONE DEFECTS IN THE JAW |
JP7156759B2 (ja) * | 2019-10-25 | 2022-10-19 | ジェレスト, インコーポレイテッド | ケイ素ベースのカンナビジオール誘導体及びその組成物 |
Family Cites Families (4)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
IL55274A (en) * | 1978-08-02 | 1982-08-31 | Yissum Res Dev Co | 4-(2,6-dihydroxy-4-(dimethylheptyl)phenyl)substituted 2-pinen-10-ol and pinane derivatives,their preparation and pharmaceutical compositions comprising them |
US5434295A (en) | 1994-02-07 | 1995-07-18 | Yissum Research Development Company | Neuroprotective pharmaceutical compositions of 4-phenylpinene derivatives and certain novel 4-phenylpinene compounds |
FR2735774B1 (fr) | 1995-06-21 | 1997-09-12 | Sanofi Sa | Utilisation de composes agonistes du recepteur cb2 humain pour la preparation de medicaments immunomodulateurs, nouveaux composes agonistes du recepteur cb2 et les compositions pharmaceutiques les contenant |
IL132661A (en) * | 1999-10-31 | 2008-11-26 | Raphael Mechoulam | Agonists specific for peripheral cannabinoid receptors |
-
1999
- 1999-10-31 IL IL132661A patent/IL132661A/en not_active IP Right Cessation
-
2000
- 2000-10-30 HU HU0203681A patent/HUP0203681A3/hu unknown
- 2000-10-30 AU AU12458/01A patent/AU778149B2/en not_active Ceased
- 2000-10-30 US US09/698,071 patent/US6864291B1/en not_active Expired - Fee Related
- 2000-10-30 WO PCT/US2000/029903 patent/WO2001032169A1/en active IP Right Grant
- 2000-10-30 JP JP2001534374A patent/JP4231906B2/ja not_active Expired - Fee Related
- 2000-10-30 NZ NZ518054A patent/NZ518054A/en unknown
- 2000-10-30 AT AT00974023T patent/ATE286389T1/de not_active IP Right Cessation
- 2000-10-30 EP EP00974023A patent/EP1244440B1/en not_active Expired - Lifetime
- 2000-10-30 DE DE60017287T patent/DE60017287T2/de not_active Expired - Lifetime
- 2000-10-30 CA CA002385928A patent/CA2385928A1/en not_active Abandoned
- 2000-10-30 KR KR1020027005566A patent/KR100770695B1/ko not_active IP Right Cessation
-
2002
- 2002-03-18 ZA ZA200202181A patent/ZA200202181B/xx unknown
- 2002-03-20 IL IL148796A patent/IL148796A/en not_active IP Right Cessation
- 2002-04-26 US US10/133,153 patent/US6903137B2/en not_active Expired - Fee Related
-
2005
- 2005-01-27 US US11/043,089 patent/US7214716B2/en not_active Expired - Fee Related
Also Published As
Publication number | Publication date |
---|---|
US20020173528A1 (en) | 2002-11-21 |
AU1245801A (en) | 2001-05-14 |
EP1244440A1 (en) | 2002-10-02 |
JP4231906B2 (ja) | 2009-03-04 |
CA2385928A1 (en) | 2001-05-10 |
KR100770695B1 (ko) | 2007-10-29 |
NZ518054A (en) | 2003-10-31 |
HUP0203681A2 (hu) | 2003-04-28 |
HUP0203681A3 (en) | 2003-05-28 |
AU778149B2 (en) | 2004-11-18 |
WO2001032169A1 (en) | 2001-05-10 |
JP2004505006A (ja) | 2004-02-19 |
EP1244440B1 (en) | 2005-01-05 |
DE60017287D1 (de) | 2005-02-10 |
EP1244440A4 (en) | 2003-05-14 |
IL148796A (en) | 2008-11-26 |
IL132661A (en) | 2008-11-26 |
ATE286389T1 (de) | 2005-01-15 |
IL132661A0 (en) | 2001-03-19 |
DE60017287T2 (de) | 2005-12-08 |
KR20030008208A (ko) | 2003-01-24 |
US20050165118A1 (en) | 2005-07-28 |
US6864291B1 (en) | 2005-03-08 |
US7214716B2 (en) | 2007-05-08 |
US6903137B2 (en) | 2005-06-07 |
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