ZA200200299B - Thiophene A2A receptor agonists. - Google Patents

Thiophene A2A receptor agonists.

Info

Publication number
ZA200200299B
ZA200200299B ZA200200299A ZA200200299A ZA200200299B ZA 200200299 B ZA200200299 B ZA 200200299B ZA 200200299 A ZA200200299 A ZA 200200299A ZA 200200299 A ZA200200299 A ZA 200200299A ZA 200200299 B ZA200200299 B ZA 200200299B
Authority
ZA
South Africa
Prior art keywords
thiophene
receptor agonists
disclosed
purposes
alkylthienyl
Prior art date
Application number
ZA200200299A
Other languages
English (en)
Inventor
Jeffrey A Zablocki
Elfatih O Elzein
Venkata P Palle
Original Assignee
Therapeutics Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Therapeutics Inc filed Critical Therapeutics Inc
Publication of ZA200200299B publication Critical patent/ZA200200299B/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H19/00—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof
    • C07H19/02—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof sharing nitrogen
    • C07H19/04—Heterocyclic radicals containing only nitrogen atoms as ring hetero atom
    • C07H19/16—Purine radicals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K49/00—Preparations for testing in vivo
    • A61K49/0004—Screening or testing of compounds for diagnosis of disorders, assessment of conditions, e.g. renal clearance, gastric emptying, testing for diabetes, allergy, rheuma, pancreas functions
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P41/00—Drugs used in surgical methods, e.g. surgery adjuvants for preventing adhesion or for vitreum substitution
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A61P7/02—Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/08—Vasodilators for multiple indications

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biotechnology (AREA)
  • Diabetes (AREA)
  • Biochemistry (AREA)
  • Rheumatology (AREA)
  • Molecular Biology (AREA)
  • Genetics & Genomics (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Epidemiology (AREA)
  • Cardiology (AREA)
  • Biomedical Technology (AREA)
  • Urology & Nephrology (AREA)
  • Toxicology (AREA)
  • Pathology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Endocrinology (AREA)
  • Hematology (AREA)
  • Pain & Pain Management (AREA)
  • Surgery (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Saccharide Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
ZA200200299A 1999-06-22 2002-01-14 Thiophene A2A receptor agonists. ZA200200299B (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US14047899P 1999-06-22 1999-06-22

Publications (1)

Publication Number Publication Date
ZA200200299B true ZA200200299B (en) 2003-08-27

Family

ID=22491411

Family Applications (1)

Application Number Title Priority Date Filing Date
ZA200200299A ZA200200299B (en) 1999-06-22 2002-01-14 Thiophene A2A receptor agonists.

Country Status (19)

Country Link
US (1) US6440948B1 (ko)
EP (1) EP1194441B1 (ko)
JP (1) JP2003502434A (ko)
KR (1) KR100463694B1 (ko)
CN (1) CN1166677C (ko)
AT (1) ATE252595T1 (ko)
AU (1) AU768530B2 (ko)
BR (1) BR0011853A (ko)
CA (1) CA2373410C (ko)
DE (1) DE60006116T2 (ko)
ES (1) ES2206259T3 (ko)
HK (1) HK1048821B (ko)
IL (2) IL147194A0 (ko)
MX (1) MXPA01013323A (ko)
NO (1) NO20016242L (ko)
NZ (1) NZ516336A (ko)
TR (1) TR200200617T2 (ko)
WO (1) WO2000078776A2 (ko)
ZA (1) ZA200200299B (ko)

Families Citing this family (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA2347512C (en) * 1998-10-16 2005-12-06 Pfizer Inc. Adenine derivatives
ES2276084T3 (es) 2002-02-15 2007-06-16 Cv Therapeutics, Inc. Revestimiento polimerico para dispositivos medicos.
TWI346109B (en) * 2004-04-30 2011-08-01 Otsuka Pharma Co Ltd 4-amino-5-cyanopyrimidine derivatives
WO2005117910A2 (en) * 2004-05-26 2005-12-15 Inotek Pharmaceuticals Corporation Purine derivatives as adenosine a1 receptor agonists and methods of use thereof
KR20070058626A (ko) * 2004-09-20 2007-06-08 이노텍 파마슈티컬스 코포레이션 퓨린 유도체 및 이것의 사용 방법
NZ568392A (en) * 2005-11-30 2011-07-29 Inotek Pharmaceuticals Corp Purine derivatives and methods of use thereof
LT2523669T (lt) 2010-01-11 2017-04-25 Inotek Pharmaceuticals Corporation Akispūdžio mažinimo būdas, derinys ir rinkinys
WO2011119969A1 (en) 2010-03-26 2011-09-29 Inotek Pharmaceuticals Corporation Method of reducing intraocular pressure in humans using n6 -cyclopentyladenosine (cpa), cpa derivatives or prodrugs thereof
RS56150B1 (sr) 2012-01-26 2017-11-30 Inotek Pharmaceuticals Corp Anhidrovani polimorfi (2r,3s,4r,5r)-5-(6-(ciklopentilamino)-9h-purin-9-yl)-3,4-dihidroksitetrahidrofuran-2-yl)} metil-nitrata i postupak njegove pripreme
KR20150139501A (ko) 2013-03-15 2015-12-11 이노텍 파마슈티컬스 코포레이션 안과용 제형
CA3049856C (en) 2017-01-13 2021-10-26 Tobishi Pharmaceutical Co., Ltd. Neutrophil activation regulator

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DK135130B (da) * 1970-12-28 1977-03-07 Takeda Chemical Industries Ltd Analogifremgangsmåde til fremstilling af 2-substituerede adenosinderivater eller syreadditionssalte deraf.
JPS4911896A (ko) * 1972-05-15 1974-02-01
JPS5518625B2 (ko) * 1973-07-26 1980-05-20
US5070877A (en) * 1988-08-11 1991-12-10 Medco Research, Inc. Novel method of myocardial imaging
WO1992017488A1 (en) * 1991-04-06 1992-10-15 Fisons Plc Atp analogues

Also Published As

Publication number Publication date
HK1048821B (zh) 2005-02-25
EP1194441A2 (en) 2002-04-10
AU5625100A (en) 2001-01-09
CA2373410A1 (en) 2000-12-28
MXPA01013323A (es) 2003-10-15
DE60006116T2 (de) 2004-07-08
KR100463694B1 (ko) 2004-12-29
WO2000078776A3 (en) 2001-06-28
JP2003502434A (ja) 2003-01-21
CN1364170A (zh) 2002-08-14
CN1166677C (zh) 2004-09-15
BR0011853A (pt) 2002-04-30
US6440948B1 (en) 2002-08-27
WO2000078776A2 (en) 2000-12-28
ATE252595T1 (de) 2003-11-15
NO20016242D0 (no) 2001-12-19
KR20020028912A (ko) 2002-04-17
TR200200617T2 (tr) 2002-06-21
IL147194A0 (en) 2002-08-14
CA2373410C (en) 2006-08-29
DE60006116D1 (de) 2003-11-27
AU768530B2 (en) 2003-12-18
NZ516336A (en) 2004-01-30
HK1048821A1 (en) 2003-04-17
NO20016242L (no) 2002-02-21
ES2206259T3 (es) 2004-05-16
EP1194441B1 (en) 2003-10-22
IL147194A (en) 2007-08-19

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