ZA200110314B - Bicyclic amino-pyrazinones compounds, a process for their preparation and pharmaceutical compositions containing them. - Google Patents

Bicyclic amino-pyrazinones compounds, a process for their preparation and pharmaceutical compositions containing them.

Info

Publication number
ZA200110314B
ZA200110314B ZA200110314A ZA200110314A ZA200110314B ZA 200110314 B ZA200110314 B ZA 200110314B ZA 200110314 A ZA200110314 A ZA 200110314A ZA 200110314 A ZA200110314 A ZA 200110314A ZA 200110314 B ZA200110314 B ZA 200110314B
Authority
ZA
South Africa
Prior art keywords
pyrazinones
compounds
preparation
pharmaceutical compositions
compositions containing
Prior art date
Application number
ZA200110314A
Other languages
English (en)
Inventor
Guillaume De Nanteuil
Philippe Gloanec
Tony Verbeuren
Alain Rupin
Marie-Odile Vallez
Original Assignee
Servier Lab
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Servier Lab filed Critical Servier Lab
Publication of ZA200110314B publication Critical patent/ZA200110314B/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
    • C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
    • C07D487/04—Ortho-condensed systems
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
    • C07K5/04—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
    • C07K5/06—Dipeptides
    • C07K5/06139—Dipeptides with the first amino acid being heterocyclic
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A61P7/02—Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
    • Y02P20/00—Technologies relating to chemical industry
    • Y02P20/50—Improvements relating to the production of bulk chemicals
    • Y02P20/55—Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups
ZA200110314A 2000-12-14 2001-12-14 Bicyclic amino-pyrazinones compounds, a process for their preparation and pharmaceutical compositions containing them. ZA200110314B (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
FR0016321A FR2818277B1 (fr) 2000-12-14 2000-12-14 Nouveaux derives bicycliques d'amino-pyrazinones, leur procede de preparation et les compositions pharmaceutiques qui les contiennent

Publications (1)

Publication Number Publication Date
ZA200110314B true ZA200110314B (en) 2003-03-12

Family

ID=8857662

Family Applications (1)

Application Number Title Priority Date Filing Date
ZA200110314A ZA200110314B (en) 2000-12-14 2001-12-14 Bicyclic amino-pyrazinones compounds, a process for their preparation and pharmaceutical compositions containing them.

Country Status (24)

Country Link
US (1) US6686358B2 (xx)
EP (1) EP1215213B1 (xx)
JP (1) JP3616599B2 (xx)
KR (1) KR100502251B1 (xx)
CN (1) CN1209363C (xx)
AR (1) AR031662A1 (xx)
AU (1) AU781614B2 (xx)
BR (1) BR0106129A (xx)
CA (1) CA2364199C (xx)
CY (1) CY1106376T1 (xx)
DE (1) DE60126046T2 (xx)
DK (1) DK1215213T3 (xx)
EA (1) EA004678B1 (xx)
ES (1) ES2280333T3 (xx)
FR (1) FR2818277B1 (xx)
HK (1) HK1047101B (xx)
HU (1) HUP0105328A3 (xx)
MX (1) MXPA01012895A (xx)
NO (1) NO322149B1 (xx)
NZ (1) NZ516129A (xx)
PL (1) PL351199A1 (xx)
PT (1) PT1215213E (xx)
SI (1) SI1215213T1 (xx)
ZA (1) ZA200110314B (xx)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20040077605A1 (en) * 2001-06-20 2004-04-22 Salvati Mark E. Fused heterocyclic succinimide compounds and analogs thereof, modulators of nuclear hormone receptor function
EP1854798A3 (en) * 2000-09-19 2007-11-28 Bristol-Myers Squibb Company Fused heterocyclic succinimide compounds and analogs thereof, modulators of nuclear hormone receptor function
US20040087548A1 (en) 2001-02-27 2004-05-06 Salvati Mark E. Fused cyclic succinimide compounds and analogs thereof, modulators of nuclear hormone receptor function
ES2310622T3 (es) * 2001-12-19 2009-01-16 Bristol-Myers Squibb Company Compuestos heterociclicos condensados y analogos de los mismos, moduladores de la funcion de los receptores nucleares de hormonas.
US7037911B2 (en) * 2002-06-26 2006-05-02 Bristol-Myers Squibb Company Amino-bicyclic pyrazinones and pyridinones as coagulation serine protease inhibitors
FR2867780B1 (fr) 2004-03-19 2006-05-19 Servier Lab Nouveaux derives de 4-oxo-4,6,7,8-tetrahydropyrrolo (1,2-a) pyrazine-6-carboxamides, leur procede de preparation et les compositions pharmaceutiques qui les contiennent
DE102018220624A1 (de) * 2018-11-29 2020-06-04 B. Braun Melsungen Ag Wässrige Zusammensetzung, insbesondere zur Behandlung von Schleimhaut und/oder Wunden

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPH05117276A (ja) * 1991-10-23 1993-05-14 Sumitomo Pharmaceut Co Ltd 新規な３環性キノキサリンジオン誘導体
NZ297360A (en) * 1994-12-22 2000-03-27 Iaf Biochem Int 5-oxo-5H-thiazolo[3,2-a]pyridine, 5-oxo-2-thia-4a,7-diaza-naphthalene, 4-oxo-octahydro-pyrrolo[1,2-a]pyrazine or 6-oxo-octahydro-pyrido-[2,1-c][1,4]thiazine derivatives and medicaments
US6057314A (en) * 1995-12-21 2000-05-02 Biochem Pharma Inc. Low molecular weight bicyclic thrombin inhibitors
US6124291A (en) * 1996-06-18 2000-09-26 Warner-Lambert Company Pyrrolo[1,2-a]pyrazine-1,4-dione serine protease inhibitors
JP2001502691A (ja) * 1996-10-24 2001-02-27 メルク エンド カンパニー インコーポレーテッド トロンビン阻害剤
US6011038A (en) * 1997-09-05 2000-01-04 Merck & Co., Inc. Pyrazinone thrombin inhibitors
CA2348530A1 (en) * 1998-10-30 2000-05-11 Merck & Co., Inc. Thrombin inhibitors
UA58636C2 (uk) * 1999-06-04 2003-08-15 Мерк Енд Ко., Інк. Піразинонові інгібітори тромбіну, фармацевтична композиція, спосіб інгібування утворення тромбів у крові, спосіб лікування станів, пов'язаних із тромбоутворенням
FR2795072B1 (fr) * 1999-06-15 2001-07-27 Adir Nouveaux derives bicycliques d'amino-pyrazinones, leur procede de preparation et les compositions pharmaceutiques qui les contiennent

Also Published As

Publication number Publication date
NO322149B1 (no) 2006-08-21
DE60126046T2 (de) 2007-11-29
EP1215213A2 (fr) 2002-06-19
CA2364199C (fr) 2007-04-10
DK1215213T3 (da) 2007-05-21
DE60126046D1 (de) 2007-03-08
KR20020048302A (ko) 2002-06-22
HUP0105328A3 (en) 2003-03-28
KR100502251B1 (ko) 2005-07-22
CN1209363C (zh) 2005-07-06
MXPA01012895A (es) 2002-11-07
SI1215213T1 (sl) 2007-04-30
ES2280333T3 (es) 2007-09-16
JP2002212184A (ja) 2002-07-31
CY1106376T1 (el) 2011-10-12
HK1047101B (zh) 2005-10-28
PT1215213E (pt) 2007-03-30
EA200101204A1 (ru) 2002-06-27
AU781614B2 (en) 2005-06-02
HUP0105328A2 (hu) 2002-07-29
CN1358723A (zh) 2002-07-17
EP1215213A3 (fr) 2002-09-25
BR0106129A (pt) 2003-04-08
HU0105328D0 (en) 2002-02-28
EA004678B1 (ru) 2004-06-24
EP1215213B1 (fr) 2007-01-17
PL351199A1 (en) 2002-06-17
US20020111341A1 (en) 2002-08-15
JP3616599B2 (ja) 2005-02-02
AU9723001A (en) 2002-06-20
NZ516129A (en) 2003-05-30
NO20016069L (no) 2002-06-17
FR2818277A1 (fr) 2002-06-21
CA2364199A1 (fr) 2002-06-14
HK1047101A1 (en) 2003-02-07
FR2818277B1 (fr) 2003-01-24
US6686358B2 (en) 2004-02-03
AR031662A1 (es) 2003-09-24
NO20016069D0 (no) 2001-12-12

Similar Documents

Publication Publication Date Title
ZA200003702B (en) Beta-carboline compounds, a process for their preparation and pharmaceutical compositions containing them.
ZA200105394B (en) Diphenylurea compounds, a process for their preparation and pharmaceutical composition containing them.
ZA200100864B (en) Piperidine-4-sulphonamides compounds, a process for their preparation and pharmaceutical compositions containing them.
PL359373A1 (en) New substituted phthalides, a process for their preparation and pharmaceutical compositions containing them
HUP0104272A3 (en) New cyclobutendione compounds, a process for their preparation and pharmaceutical compositions containing them
HUP0302515A3 (en) Sulfanidothienopyrimidines, process for their preparation and pharmaceutical compositions containing them
ZA200100565B (en) Benzenesulfonamide compounds, a process for their preparation and pharmaceutical compositions containing them.
ZA200110314B (en) Bicyclic amino-pyrazinones compounds, a process for their preparation and pharmaceutical compositions containing them.
ZA200202220B (en) Indenoindolone compounds, a process for their preparation and pharmaceutical compositions containing them.
ZA200202030B (en) Isoindoloindolone compounds, a process for their preparation and pharmaceutical compositions containing them.
ZA200106203B (en) Benzothiadiazine compounds, a process for their preparation and pharmaceutical compositions containing them.
ZA200205598B (en) Benzenesulphonamide compounds, a process for their preparation and pharmaceutical compositions containing them.
ZA200402657B (en) Isoquinoline compounds, a process for their preparation and pharmaceutical compositions containing them.
ZA200205666B (en) N-benzylpiperazine compounds, a process for their preparation and pharmaceutical compositions containing them.
HUP0002277A3 (en) Bicyclic amino-pyrazinone compounds, a process for their preparation and pharmaceutical compositions containing them
HK1053646A1 (en) BenzoÄBÜpyranoÄ3,2-HÜacridin-7-one compounds, a process for their preparation and pharmaceutical compositions containing them
ZA200103065B (en) Heterocycloalkylbenzocyclobutane and heteroarylbenzocyclobutane compounds, a process for their preparation and pharmaceutical compositions containing them.
ZA200103064B (en) Cyclobutaindolecarboxamide compounds, a process for their preparation and pharmaceutical compositions containing them.
ZA200203086B (en) Pyrimidin-4-one compounds, a process for their preparation and pharmaceutical compositions containing them.
ZA200204757B (en) Indenoidolone compounds, a process for their preparation and pharmaceutical compositions containing them.
HK1048471A1 (en) Cycloheptene compounds, a process for their preparation and pharmaceutical compositions containing them.
ZA200101338B (en) 6-sulphamoyl-3-quinolylphosphonic acid compounds, a process for their preparation and pharmaceutical compositions containing them.
ZA200204865B (en) Cyclic α-amino-y-hydroxyaminde compounds, a process for their preparation and pharmaceutical compositions containing them.
ZA200205597B (en) Benzenesulphonamide compounds, a process for their preparation and pharmaceutical compositions containing them.