ZA200108718B - Thiazolidinedione derivative and its use as antidiabetic. - Google Patents

Thiazolidinedione derivative and its use as antidiabetic.

Info

Publication number
ZA200108718B
ZA200108718B ZA200108718A ZA200108718A ZA200108718B ZA 200108718 B ZA200108718 B ZA 200108718B ZA 200108718 A ZA200108718 A ZA 200108718A ZA 200108718 A ZA200108718 A ZA 200108718A ZA 200108718 B ZA200108718 B ZA 200108718B
Authority
ZA
South Africa
Prior art keywords
antidiabetic
thiazolidinedione derivative
thiazolidinedione
derivative
Prior art date
Application number
ZA200108718A
Other languages
English (en)
Inventor
Blackler Paul David James
Giles Robert Gordon
Stephen Moore
Sasse Michael John
Original Assignee
Smithkline Beecham Plc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from GBGB9909471.6A external-priority patent/GB9909471D0/en
Priority claimed from GBGB9912195.6A external-priority patent/GB9912195D0/en
Application filed by Smithkline Beecham Plc filed Critical Smithkline Beecham Plc
Publication of ZA200108718B publication Critical patent/ZA200108718B/xx

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D417/00Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
    • C07D417/02Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings
    • C07D417/12Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings linked by a chain containing hetero atoms as chain links
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/41Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
    • A61K31/425Thiazoles
    • A61K31/427Thiazoles not condensed and containing further heterocyclic rings
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00Drugs for disorders of the metabolism
    • A61P3/08Drugs for disorders of the metabolism for glucose homeostasis
    • A61P3/10Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Diabetes (AREA)
  • Medicinal Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Hematology (AREA)
  • Endocrinology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Obesity (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Emergency Medicine (AREA)
  • Epidemiology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Thiazole And Isothizaole Compounds (AREA)
  • Steroid Compounds (AREA)
ZA200108718A 1999-04-23 2001-10-23 Thiazolidinedione derivative and its use as antidiabetic. ZA200108718B (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
GBGB9909471.6A GB9909471D0 (en) 1999-04-23 1999-04-23 Novel compounds
GBGB9912195.6A GB9912195D0 (en) 1999-05-25 1999-05-25 Novel pharmaceutical
PCT/GB2000/001522 WO2000064893A2 (fr) 1999-04-23 2000-04-19 Nouvel agent pharmaceutique

Publications (1)

Publication Number Publication Date
ZA200108718B true ZA200108718B (en) 2002-12-03

Family

ID=26315459

Family Applications (1)

Application Number Title Priority Date Filing Date
ZA200108718A ZA200108718B (en) 1999-04-23 2001-10-23 Thiazolidinedione derivative and its use as antidiabetic.

Country Status (36)

Country Link
EP (2) EP1277753A1 (fr)
JP (1) JP2002543076A (fr)
KR (1) KR100744361B1 (fr)
CN (1) CN1152878C (fr)
AP (1) AP1607A (fr)
AR (2) AR023750A1 (fr)
AU (2) AU4307200A (fr)
BG (1) BG65517B1 (fr)
BR (1) BR0009935A (fr)
CA (1) CA2370262A1 (fr)
CO (1) CO5170419A1 (fr)
CZ (1) CZ20013801A3 (fr)
DZ (1) DZ3164A1 (fr)
EA (1) EA003031B1 (fr)
EG (1) EG23937A (fr)
GC (1) GC0000250A (fr)
HK (1) HK1045152A1 (fr)
HR (1) HRP20010774A2 (fr)
HU (1) HUP0200937A3 (fr)
IL (1) IL146115A0 (fr)
MA (1) MA26786A1 (fr)
MX (1) MXPA01010822A (fr)
MY (1) MY138673A (fr)
NO (1) NO320587B1 (fr)
NZ (1) NZ515167A (fr)
OA (1) OA11873A (fr)
PE (1) PE20010045A1 (fr)
PL (1) PL351685A1 (fr)
SK (1) SK14932001A3 (fr)
TR (1) TR200103060T2 (fr)
TW (1) TWI288749B (fr)
UA (1) UA67845C2 (fr)
UY (1) UY26119A1 (fr)
WO (1) WO2000064893A2 (fr)
YU (1) YU75401A (fr)
ZA (1) ZA200108718B (fr)

Families Citing this family (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6664278B2 (en) 1997-12-16 2003-12-16 Smithkline Beecham P.L.C. Hydrate of 5-[4-[2-(N-methyl-N-(2-pyridil)amino)ethoxy]benzyl]thiazolidine-2,4-dione maleic acid salt
US20020137940A1 (en) 1997-12-16 2002-09-26 Smithkline Beecham P.L.C. 5-[4-[2-(N-methyl-N-(2-pyridyl)amino)ethoxy]benzyl]thiazolidine-2, 4-dione, maleic acid salt, hydrate as pharmaceutical
GB9726568D0 (en) 1997-12-16 1998-02-11 Smithkline Beecham Plc Novel pharmaceutical
IL145796A0 (en) * 1999-04-13 2002-07-25 Us Health Production of attenuated chimeric respiratory syncytial virus vaccines from cloned nucleotide sequences
EP1173435B1 (fr) 1999-04-23 2003-07-30 SmithKline Beecham plc Nouvelle forme polymorphe du sel d'acide 5- 4- 2- (n-methyl-n-( 2-pyridyl)amino) ethoxy]benzyl] thiazolidine-2, 4-dione,maleique
TR200103061T2 (tr) 1999-04-23 2002-05-21 Smithkline Beecham P.L.C. Yeni farmasötik madde.
GB0006133D0 (en) 2000-03-14 2000-05-03 Smithkline Beecham Plc Novel pharmaceutical
US7241895B2 (en) * 2000-09-26 2007-07-10 Dr. Reddy's Laboratories Limited Polymorphic forms of 5-[4-[2-[n-methyl-n-(2-pyridyl)amino[ethoxy]benzyl] thiazolidine-2,4-dione maleate and process for their preparation
WO2004062667A1 (fr) * 2003-01-08 2004-07-29 Dr. Reddy's Laboratories Limited Forme amorphe du maleate de rosiglitazone et procede de preparation
GB0307259D0 (en) * 2003-03-28 2003-05-07 Glaxo Group Ltd Process
EP1468997A3 (fr) * 2003-04-18 2004-11-03 CHEMI S.p.A. Formes polymorphes de maléate de rosiglitatone
GB2405403A (en) * 2003-08-29 2005-03-02 Cipla Ltd Rosiglitazone maleate of particular polymorphic forms and methods of preparing rosiglitazone free base
ITMI20041537A1 (it) * 2004-07-28 2004-10-28 Chemi Spa Nuova forma polimorfa del rosiglitazone maleato
CZ298424B6 (cs) * 2005-05-24 2007-09-26 Zentiva, A. S. Zpusob krystalizace rosiglitazonu a jeho derivátuze smesných rozpouštedel
TW201336497A (zh) * 2007-02-08 2013-09-16 Daiichi Sankyo Co Ltd 噻唑啶二酮化合物之結晶型及其製法

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ATE186724T1 (de) * 1987-09-04 1999-12-15 Beecham Group Plc Substituierte thiazolidindionderivate
GB9218830D0 (en) * 1992-09-05 1992-10-21 Smithkline Beecham Plc Novel compounds
GB9726566D0 (en) * 1997-12-16 1998-02-11 Smithkline Beecham Plc Novel pharmaceutical
GB9726568D0 (en) * 1997-12-16 1998-02-11 Smithkline Beecham Plc Novel pharmaceutical
GB9726563D0 (en) * 1997-12-16 1998-02-11 Smithkline Beecham Plc Novel pharmaceutical

Also Published As

Publication number Publication date
TR200103060T2 (tr) 2002-05-21
HUP0200937A2 (en) 2002-08-28
EG23937A (en) 2008-01-14
KR100744361B1 (ko) 2007-07-30
IL146115A0 (en) 2002-07-25
NZ515167A (en) 2004-02-27
AU2755102A (en) 2002-05-16
NO20015148L (no) 2001-12-17
CN1152878C (zh) 2004-06-09
WO2000064893A3 (fr) 2001-01-25
CZ20013801A3 (cs) 2002-07-17
AP2001002329A0 (en) 2001-12-31
CN1355800A (zh) 2002-06-26
HRP20010774A2 (en) 2002-10-31
AR023750A1 (es) 2002-09-04
PE20010045A1 (es) 2001-03-10
BG106122A (en) 2002-05-31
MXPA01010822A (es) 2002-06-04
AR023560A1 (es) 2002-09-04
CO5170419A1 (es) 2002-06-27
AP1607A (en) 2006-05-03
AU771342B2 (en) 2004-03-18
EP1277753A1 (fr) 2003-01-22
UA67845C2 (uk) 2004-07-15
AU4307200A (en) 2000-11-10
YU75401A (sh) 2004-09-03
BG65517B1 (bg) 2008-10-31
SK14932001A3 (sk) 2002-02-05
KR20010110804A (ko) 2001-12-13
EA003031B1 (ru) 2002-12-26
PL351685A1 (en) 2003-06-02
DZ3164A1 (fr) 2000-11-02
OA11873A (en) 2006-03-27
UY26119A1 (es) 2000-12-29
WO2000064893A2 (fr) 2000-11-02
HUP0200937A3 (en) 2004-03-29
TWI288749B (en) 2007-10-21
JP2002543076A (ja) 2002-12-17
MA26786A1 (fr) 2004-12-20
NO320587B1 (no) 2005-12-27
CA2370262A1 (fr) 2000-11-02
EA200101122A1 (ru) 2002-04-25
BR0009935A (pt) 2002-04-16
HK1045152A1 (zh) 2002-11-15
EP1175418A2 (fr) 2002-01-30
MY138673A (en) 2009-07-31
GC0000250A (en) 2006-11-01
NO20015148D0 (no) 2001-10-22

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