ZA200102589B - Propanolamine derivatives substituted with heterocyclic compounds, methods for their production, pharmaceutical compositions containing said compounds and the use thereof. - Google Patents
Propanolamine derivatives substituted with heterocyclic compounds, methods for their production, pharmaceutical compositions containing said compounds and the use thereof.Info
- Publication number
- ZA200102589B ZA200102589B ZA200102589A ZA200102589A ZA200102589B ZA 200102589 B ZA200102589 B ZA 200102589B ZA 200102589 A ZA200102589 A ZA 200102589A ZA 200102589 A ZA200102589 A ZA 200102589A ZA 200102589 B ZA200102589 B ZA 200102589B
- Authority
- ZA
- South Africa
- Prior art keywords
- compounds
- production
- methods
- pharmaceutical compositions
- compositions containing
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
- C07D417/14—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing three or more hetero rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
- C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
- C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D213/60—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D213/72—Nitrogen atoms
- C07D213/74—Amino or imino radicals substituted by hydrocarbon or substituted hydrocarbon radicals
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/06—Antihyperlipidemics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
- C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
- C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D213/60—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D213/78—Carbon atoms having three bonds to hetero atoms, with at the most one bond to halogen, e.g. ester or nitrile radicals
- C07D213/79—Acids; Esters
- C07D213/80—Acids; Esters in position 3
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
- C07D401/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a chain containing hetero atoms as chain links
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/14—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing three or more hetero rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D409/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms
- C07D409/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings
- C07D409/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings linked by a chain containing hetero atoms as chain links
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D409/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms
- C07D409/14—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing three or more hetero rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
- C07D413/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings
- C07D413/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings linked by a chain containing hetero atoms as chain links
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
- C07D413/14—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing three or more hetero rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
- C07D417/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings
- C07D417/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings linked by a chain containing hetero atoms as chain links
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Obesity (AREA)
- Hematology (AREA)
- Diabetes (AREA)
- Urology & Nephrology (AREA)
- Vascular Medicine (AREA)
- Cardiology (AREA)
- Heart & Thoracic Surgery (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Pyridine Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
- Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
- Steroid Compounds (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
DE19845402A DE19845402B4 (de) | 1998-10-02 | 1998-10-02 | Mit Heterocyclen substituierte Propanolaminderivate, Verfahren zu deren Herstellung, diese Verbindungen enthaltende Arzneimittel und deren Verwendung |
Publications (1)
Publication Number | Publication Date |
---|---|
ZA200102589B true ZA200102589B (en) | 2002-02-27 |
Family
ID=7883184
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
ZA200102589A ZA200102589B (en) | 1998-10-02 | 2001-03-29 | Propanolamine derivatives substituted with heterocyclic compounds, methods for their production, pharmaceutical compositions containing said compounds and the use thereof. |
Country Status (21)
Country | Link |
---|---|
US (1) | US6303639B1 (ko) |
EP (1) | EP1117661B1 (ko) |
JP (1) | JP2002526539A (ko) |
KR (1) | KR100611030B1 (ko) |
CN (1) | CN1150185C (ko) |
AR (1) | AR021843A1 (ko) |
AT (1) | ATE267825T1 (ko) |
AU (1) | AU760412B2 (ko) |
BR (1) | BR9914266A (ko) |
CA (1) | CA2346083A1 (ko) |
DE (2) | DE19845402B4 (ko) |
DK (1) | DK1117661T3 (ko) |
ES (1) | ES2219065T3 (ko) |
HK (1) | HK1040249B (ko) |
HU (1) | HUP0103893A3 (ko) |
PL (1) | PL347105A1 (ko) |
PT (1) | PT1117661E (ko) |
RU (1) | RU2219176C2 (ko) |
TR (1) | TR200100895T2 (ko) |
WO (1) | WO2000020410A1 (ko) |
ZA (1) | ZA200102589B (ko) |
Families Citing this family (18)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
DE19845406C2 (de) * | 1998-10-02 | 2001-10-18 | Aventis Pharma Gmbh | Substituierte 1,3-Diaryl-2-pyridin-2-yl-3-(pyridin-2-ylamino)- propanolderivate, Verfahren zu deren Herstellung, diese Verbindungen enthaltende Arzneimittel und deren Verwendung |
IL156548A0 (en) * | 2000-12-21 | 2004-01-04 | Aventis Pharma Gmbh | Diphenyl azetidinone derivatives, method for the production thereof, medicaments containing these compounds, and their use |
CN1638801A (zh) * | 2001-08-22 | 2005-07-13 | 安万特医药德国有限公司 | 芳基取代的丙醇胺衍生物与其他活性成分的联用产品及其应用 |
US7161008B2 (en) * | 2002-05-03 | 2007-01-09 | Sanofi - Aventis Deutschland GmbH | Optically active β-aminoketones, optically active 1,3-amino alcohols and processes for preparing them |
DE10219987A1 (de) * | 2002-05-03 | 2004-04-08 | Aventis Pharma Deutschland Gmbh | Optisch aktive β-Aminoketone, optisch aktive 1,3-Aminoalkohole und Verfahren zu deren Herstellung |
GB0307918D0 (en) | 2003-04-05 | 2003-05-14 | Astrazeneca Ab | Therapeutic use |
WO2011119869A1 (en) * | 2010-03-24 | 2011-09-29 | Medical University Of South Carolina | Compositions and methods for the treatment of degenerative diseases |
EP2995317A1 (en) | 2010-05-26 | 2016-03-16 | Satiogen Pharmaceuticals, Inc. | Bile acid recycling inhibitors and satiogens for treatment of diabetes, obesity, and inflammatory gastrointestinal conditions |
MX354242B (es) | 2011-10-28 | 2018-02-20 | Lumena Pharmaceuticals Inc | Nhibidores de la recirculación de ácidos biliares para el tratamiento de enfermedades hepáticas colestásicas pediátricas. |
CN107375291A (zh) | 2011-10-28 | 2017-11-24 | 鲁美纳医药公司 | 用于治疗高胆血症和胆汁淤积性肝病的胆汁酸再循环抑制剂 |
MX2015013193A (es) | 2013-03-15 | 2016-04-15 | Lumena Pharmaceuticals Inc | Inhibidores del reciclaje de acidos biliares para el tratamiento de colangitis esclerosante primaria y enfermedad inflamatoria intestinal. |
JP2016514678A (ja) | 2013-03-15 | 2016-05-23 | ルメナ ファーマシューティカルズ エルエルシー | バレット食道と胃食道逆流性疾患を処置するための胆汁酸再利用阻害剤 |
US11232719B1 (en) | 2019-09-04 | 2022-01-25 | Ward-Kraft, Inc. | Single ply wristband with printable coating |
US11238759B1 (en) | 2015-10-29 | 2022-02-01 | Ward-Kraft, Inc. | Single ply wristband with printable coating |
JP2022519905A (ja) | 2019-02-12 | 2022-03-25 | ミルム ファーマシューティカルズ インコーポレイテッド | 胆汁酸塩排出ポンプ欠損症の患者における遺伝子型およびasbtiに対する用量依存的反応 |
USD988404S1 (en) | 2020-02-14 | 2023-06-06 | Rekon, Llc | Wristband label form with single strap wristbands |
USD941917S1 (en) | 2020-02-18 | 2022-01-25 | Ward-Kraft, Inc. | Combination wristband label form with extender |
USD967253S1 (en) | 2020-02-26 | 2022-10-18 | Ward-Kraft, Inc. | Wristband form with extender |
Family Cites Families (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
ES2223091T3 (es) | 1997-04-04 | 2005-02-16 | Aventis Pharma Deutschland Gmbh | Derivados de propanolamina hipolipidemicos. |
-
1998
- 1998-10-02 DE DE19845402A patent/DE19845402B4/de not_active Expired - Fee Related
-
1999
- 1999-09-18 CA CA002346083A patent/CA2346083A1/en not_active Abandoned
- 1999-09-18 ES ES99948790T patent/ES2219065T3/es not_active Expired - Lifetime
- 1999-09-18 AT AT99948790T patent/ATE267825T1/de not_active IP Right Cessation
- 1999-09-18 EP EP99948790A patent/EP1117661B1/de not_active Expired - Lifetime
- 1999-09-18 TR TR2001/00895T patent/TR200100895T2/xx unknown
- 1999-09-18 DE DE59909609T patent/DE59909609D1/de not_active Expired - Lifetime
- 1999-09-18 DK DK99948790T patent/DK1117661T3/da active
- 1999-09-18 WO PCT/EP1999/006932 patent/WO2000020410A1/de not_active Application Discontinuation
- 1999-09-18 CN CNB998116351A patent/CN1150185C/zh not_active Expired - Fee Related
- 1999-09-18 BR BR9914266-0A patent/BR9914266A/pt not_active Application Discontinuation
- 1999-09-18 PT PT99948790T patent/PT1117661E/pt unknown
- 1999-09-18 JP JP2000574523A patent/JP2002526539A/ja active Pending
- 1999-09-18 PL PL99347105A patent/PL347105A1/xx not_active Application Discontinuation
- 1999-09-18 RU RU2001111815/04A patent/RU2219176C2/ru not_active IP Right Cessation
- 1999-09-18 HU HU0103893A patent/HUP0103893A3/hu unknown
- 1999-09-18 AU AU61925/99A patent/AU760412B2/en not_active Ceased
- 1999-09-18 KR KR1020017004129A patent/KR100611030B1/ko not_active IP Right Cessation
- 1999-09-29 US US09/407,973 patent/US6303639B1/en not_active Expired - Lifetime
- 1999-09-30 AR ARP990104958A patent/AR021843A1/es unknown
-
2001
- 2001-03-29 ZA ZA200102589A patent/ZA200102589B/xx unknown
-
2002
- 2002-03-15 HK HK02102007.5A patent/HK1040249B/zh not_active IP Right Cessation
Also Published As
Publication number | Publication date |
---|---|
EP1117661B1 (de) | 2004-05-26 |
PT1117661E (pt) | 2004-09-30 |
HK1040249B (zh) | 2005-04-01 |
DK1117661T3 (da) | 2004-08-30 |
KR100611030B1 (ko) | 2006-08-10 |
ES2219065T3 (es) | 2004-11-16 |
WO2000020410A1 (de) | 2000-04-13 |
DE59909609D1 (de) | 2004-07-01 |
AU6192599A (en) | 2000-04-26 |
CN1150185C (zh) | 2004-05-19 |
CA2346083A1 (en) | 2000-04-13 |
HUP0103893A2 (hu) | 2002-05-29 |
AU760412B2 (en) | 2003-05-15 |
KR20010103593A (ko) | 2001-11-23 |
EP1117661A1 (de) | 2001-07-25 |
DE19845402A1 (de) | 2000-04-13 |
AR021843A1 (es) | 2002-08-07 |
TR200100895T2 (tr) | 2001-12-21 |
ATE267825T1 (de) | 2004-06-15 |
BR9914266A (pt) | 2001-11-06 |
US6303639B1 (en) | 2001-10-16 |
HK1040249A1 (en) | 2002-05-31 |
RU2219176C2 (ru) | 2003-12-20 |
PL347105A1 (en) | 2002-03-25 |
DE19845402B4 (de) | 2005-04-07 |
CN1321154A (zh) | 2001-11-07 |
JP2002526539A (ja) | 2002-08-20 |
HUP0103893A3 (en) | 2002-10-28 |
Similar Documents
Publication | Publication Date | Title |
---|---|---|
ZA200102588B (en) | Aryl-substituted propanolamine derivatives, methods for their production, medicaments containing said compounds and their use. | |
HUP0200312A3 (en) | Substituted 2-phenylbenzimidazoles, pharmaceutical compositions containing them, the production thereof and their use | |
ZA200107989B (en) | 1,4-benzothiazepine-1,1-dioxide derivatives substituted by sugar radicals, methods for the production thereof, medicaments containing these compounds and the use thereof. | |
IL144501A0 (en) | Epothilone derivatives, methods for the preparation thereof and pharmaceutical compositions containing the same | |
IL176005A0 (en) | 2,6-bisheteroaryl-4-aminopyrimidine derivatives and pharmaceutical compositions containing the same | |
HK1084123A1 (en) | Novel fluoroglycoside heterocyclic derivatives, pharmaceutical products containing said compounds and the use thereof | |
HUP0203766A3 (en) | 5-pyridyl-1,3-azole compounds, process for producing the same and use thereof and pharmaceutical compositions containing them | |
HUP0400540A3 (en) | 2-pyrazolin-5-one derivatives, their use and pharmaceutical compositions containing them | |
ZA200102589B (en) | Propanolamine derivatives substituted with heterocyclic compounds, methods for their production, pharmaceutical compositions containing said compounds and the use thereof. | |
MXPA03000873A (es) | Derivados de quinazolina, medicamentos que contienen estos compuestos, su uso y metodos para la produccion de los mismos. | |
HUP0101333A3 (en) | Diazepan derivatives and their salts, pharmaceutical compositions containing the same | |
ZA200410211B (en) | Quinuclidine derivatives and pharmaceutical compositions containing the same. | |
ZA974984B (en) | New substituted thiazolidine-2,4-dione derivatives, processes for the obtaining thereof, and pharmaceutical compositions containing them. | |
IL139480A0 (en) | Epothilone derivatives, processes for the preparation thereof and pharmaceutical compositions containing the same | |
HUP9803040A3 (en) | Thiazole derivatives, process for the preparation thereof, use thereof and pharmaceutical compositions containing them | |
IL146104A0 (en) | Substituted bicyclic heterocyclic compounds, processes for their preparation and pharmaceutical compositions containing the same | |
HUP0202736A3 (en) | Substituted aromatic-ring compounds, process for producing the same, and pharmaceutical compositions containing them and use thereof | |
HK1052007A1 (en) | Novel heterocyclic derivatives, preparation methodand pharmaceutical compositions containing same. | |
HK1051533A1 (en) | Substituted 1,3-diaryl-2-pyridine-2-yl-3-(pyridine-2-ylamino)-propanol derivatives, methods for their production, pharmaceutical compositions containing the same and their use. | |
HUP0200928A3 (en) | Pyrido-thieno-diazepines, method for the production thereof and pharmaceutical compositions containing said pyrido-thieno-diazepines | |
HUP0201281A3 (en) | (1-phenacy-3-phenyl-3-piperidylethyl)piperidine derivatives, method for the production thereof and pharmaceutical compositions containing the same | |
HRP20020047B1 (en) | sTREPTOGRAMIN DERIVATIVES, PRODUCTION THEREOF AND COMPOSITIONS CONTAINING THE SAME | |
HUP9803041A3 (en) | Thiazole derivatives, process for the preparation thereof, use thereof and pharmaceutical compositions containing them | |
SI1204675T1 (en) | Streptogramin derivatives, production thereof and compositions containing the same | |
HU9801085D0 (en) | Piperazinyl-alkyl-benzofurane derivatives, pharmaceutical compositions containing them as active component and process for producing the active component |