HUP0103893A3 - Propanolamine derivatives substituted with heterocyclic compounds, methods for their production, pharmaceutical compositions containing them and use thereof - Google Patents
Propanolamine derivatives substituted with heterocyclic compounds, methods for their production, pharmaceutical compositions containing them and use thereofInfo
- Publication number
- HUP0103893A3 HUP0103893A3 HU0103893A HUP0103893A HUP0103893A3 HU P0103893 A3 HUP0103893 A3 HU P0103893A3 HU 0103893 A HU0103893 A HU 0103893A HU P0103893 A HUP0103893 A HU P0103893A HU P0103893 A3 HUP0103893 A3 HU P0103893A3
- Authority
- HU
- Hungary
- Prior art keywords
- production
- methods
- pharmaceutical compositions
- compositions containing
- heterocyclic compounds
- Prior art date
Links
- 150000002391 heterocyclic compounds Chemical group 0.000 title 1
- 239000008194 pharmaceutical composition Substances 0.000 title 1
- 150000003152 propanolamines Chemical group 0.000 title 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
- C07D417/14—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing three or more hetero rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
- C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
- C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D213/60—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D213/72—Nitrogen atoms
- C07D213/74—Amino or imino radicals substituted by hydrocarbon or substituted hydrocarbon radicals
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/06—Antihyperlipidemics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
- C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
- C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D213/60—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D213/78—Carbon atoms having three bonds to hetero atoms, with at the most one bond to halogen, e.g. ester or nitrile radicals
- C07D213/79—Acids; Esters
- C07D213/80—Acids; Esters in position 3
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
- C07D401/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a chain containing hetero atoms as chain links
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/14—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing three or more hetero rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D409/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms
- C07D409/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings
- C07D409/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings linked by a chain containing hetero atoms as chain links
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D409/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms
- C07D409/14—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing three or more hetero rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
- C07D413/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings
- C07D413/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings linked by a chain containing hetero atoms as chain links
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
- C07D413/14—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing three or more hetero rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
- C07D417/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings
- C07D417/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings linked by a chain containing hetero atoms as chain links
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Public Health (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- Diabetes (AREA)
- Obesity (AREA)
- Hematology (AREA)
- Cardiology (AREA)
- Urology & Nephrology (AREA)
- Vascular Medicine (AREA)
- Heart & Thoracic Surgery (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Pyridine Compounds (AREA)
- Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
- Steroid Compounds (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Plural Heterocyclic Compounds (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| DE19845402A DE19845402B4 (de) | 1998-10-02 | 1998-10-02 | Mit Heterocyclen substituierte Propanolaminderivate, Verfahren zu deren Herstellung, diese Verbindungen enthaltende Arzneimittel und deren Verwendung |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| HUP0103893A2 HUP0103893A2 (hu) | 2002-05-29 |
| HUP0103893A3 true HUP0103893A3 (en) | 2002-10-28 |
Family
ID=7883184
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| HU0103893A HUP0103893A3 (en) | 1998-10-02 | 1999-09-18 | Propanolamine derivatives substituted with heterocyclic compounds, methods for their production, pharmaceutical compositions containing them and use thereof |
Country Status (21)
| Country | Link |
|---|---|
| US (1) | US6303639B1 (hu) |
| EP (1) | EP1117661B1 (hu) |
| JP (1) | JP2002526539A (hu) |
| KR (1) | KR100611030B1 (hu) |
| CN (1) | CN1150185C (hu) |
| AR (1) | AR021843A1 (hu) |
| AT (1) | ATE267825T1 (hu) |
| AU (1) | AU760412B2 (hu) |
| BR (1) | BR9914266A (hu) |
| CA (1) | CA2346083A1 (hu) |
| DE (2) | DE19845402B4 (hu) |
| DK (1) | DK1117661T3 (hu) |
| ES (1) | ES2219065T3 (hu) |
| HK (1) | HK1040249B (hu) |
| HU (1) | HUP0103893A3 (hu) |
| PL (1) | PL347105A1 (hu) |
| PT (1) | PT1117661E (hu) |
| RU (1) | RU2219176C2 (hu) |
| TR (1) | TR200100895T2 (hu) |
| WO (1) | WO2000020410A1 (hu) |
| ZA (1) | ZA200102589B (hu) |
Families Citing this family (18)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE19845406C2 (de) * | 1998-10-02 | 2001-10-18 | Aventis Pharma Gmbh | Substituierte 1,3-Diaryl-2-pyridin-2-yl-3-(pyridin-2-ylamino)- propanolderivate, Verfahren zu deren Herstellung, diese Verbindungen enthaltende Arzneimittel und deren Verwendung |
| HUP0401073A2 (hu) * | 2000-12-21 | 2004-09-28 | Aventis Pharma Deutschland Gmbh. | Difenilazetidinon-származékok, eljárás előállításukra és ezeket tartalmazó gyógyszerkészítmények és alkalmazásuk |
| CN1638801A (zh) * | 2001-08-22 | 2005-07-13 | 安万特医药德国有限公司 | 芳基取代的丙醇胺衍生物与其他活性成分的联用产品及其应用 |
| US7161008B2 (en) * | 2002-05-03 | 2007-01-09 | Sanofi - Aventis Deutschland GmbH | Optically active β-aminoketones, optically active 1,3-amino alcohols and processes for preparing them |
| DE10219987A1 (de) * | 2002-05-03 | 2004-04-08 | Aventis Pharma Deutschland Gmbh | Optisch aktive β-Aminoketone, optisch aktive 1,3-Aminoalkohole und Verfahren zu deren Herstellung |
| GB0307918D0 (en) | 2003-04-05 | 2003-05-14 | Astrazeneca Ab | Therapeutic use |
| US20130137728A1 (en) * | 2010-03-24 | 2013-05-30 | MUSC Foundation for Research and Development | Compositions and Methods for the Treatment of Degenerative Diseases |
| ES2552657T3 (es) | 2010-05-26 | 2015-12-01 | Satiogen Pharmaceuticals, Inc. | Inhibidores del reciclado de ácidos biliares y saciógenos para el tratamiento de diabetes, obesidad, y afecciones gastrointestinales inflamatorias |
| EP2770990A4 (en) | 2011-10-28 | 2015-03-11 | Lumena Pharmaceuticals Inc | Gallic acid refluxing agent for the treatment of hypertension and chronic liver disease |
| EP2771003B1 (en) | 2011-10-28 | 2017-04-19 | Lumena Pharmaceuticals LLC | Bile acid recycling inhibitors for treatment of pediatric cholestatic liver diseases |
| WO2014144485A1 (en) | 2013-03-15 | 2014-09-18 | Lumena Pharmaceuticals, Inc. | Bile acid recycling inhibitors for treatment of barrett's esophagus and gastroesophageal reflux disease |
| CA2907230A1 (en) | 2013-03-15 | 2014-09-18 | Lumena Pharmaceuticals, Inc. | Bile acid recycling inhibitors for treatment of primary sclerosing cholangitis and inflammatory bowel disease |
| US11232719B1 (en) | 2019-09-04 | 2022-01-25 | Ward-Kraft, Inc. | Single ply wristband with printable coating |
| US11238759B1 (en) | 2015-10-29 | 2022-02-01 | Ward-Kraft, Inc. | Single ply wristband with printable coating |
| BR112021015815A2 (pt) | 2019-02-12 | 2022-01-18 | Mirum Pharmaceuticals Inc | Métodos para tratar colestase |
| USD988404S1 (en) | 2020-02-14 | 2023-06-06 | Rekon, Llc | Wristband label form with single strap wristbands |
| USD941917S1 (en) | 2020-02-18 | 2022-01-25 | Ward-Kraft, Inc. | Combination wristband label form with extender |
| USD967253S1 (en) | 2020-02-26 | 2022-10-18 | Ward-Kraft, Inc. | Wristband form with extender |
Family Cites Families (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| ES2223091T3 (es) * | 1997-04-04 | 2005-02-16 | Aventis Pharma Deutschland Gmbh | Derivados de propanolamina hipolipidemicos. |
-
1998
- 1998-10-02 DE DE19845402A patent/DE19845402B4/de not_active Expired - Fee Related
-
1999
- 1999-09-18 RU RU2001111815/04A patent/RU2219176C2/ru not_active IP Right Cessation
- 1999-09-18 WO PCT/EP1999/006932 patent/WO2000020410A1/de not_active Application Discontinuation
- 1999-09-18 DK DK99948790T patent/DK1117661T3/da active
- 1999-09-18 BR BR9914266-0A patent/BR9914266A/pt not_active Application Discontinuation
- 1999-09-18 TR TR2001/00895T patent/TR200100895T2/xx unknown
- 1999-09-18 HU HU0103893A patent/HUP0103893A3/hu unknown
- 1999-09-18 JP JP2000574523A patent/JP2002526539A/ja active Pending
- 1999-09-18 KR KR1020017004129A patent/KR100611030B1/ko not_active IP Right Cessation
- 1999-09-18 CA CA002346083A patent/CA2346083A1/en not_active Abandoned
- 1999-09-18 PT PT99948790T patent/PT1117661E/pt unknown
- 1999-09-18 AT AT99948790T patent/ATE267825T1/de not_active IP Right Cessation
- 1999-09-18 AU AU61925/99A patent/AU760412B2/en not_active Ceased
- 1999-09-18 PL PL99347105A patent/PL347105A1/xx not_active Application Discontinuation
- 1999-09-18 DE DE59909609T patent/DE59909609D1/de not_active Expired - Lifetime
- 1999-09-18 ES ES99948790T patent/ES2219065T3/es not_active Expired - Lifetime
- 1999-09-18 EP EP99948790A patent/EP1117661B1/de not_active Expired - Lifetime
- 1999-09-18 CN CNB998116351A patent/CN1150185C/zh not_active Expired - Fee Related
- 1999-09-29 US US09/407,973 patent/US6303639B1/en not_active Expired - Lifetime
- 1999-09-30 AR ARP990104958A patent/AR021843A1/es unknown
-
2001
- 2001-03-29 ZA ZA200102589A patent/ZA200102589B/xx unknown
-
2002
- 2002-03-15 HK HK02102007.5A patent/HK1040249B/zh not_active IP Right Cessation
Also Published As
| Publication number | Publication date |
|---|---|
| DE19845402A1 (de) | 2000-04-13 |
| HUP0103893A2 (hu) | 2002-05-29 |
| TR200100895T2 (tr) | 2001-12-21 |
| CA2346083A1 (en) | 2000-04-13 |
| US6303639B1 (en) | 2001-10-16 |
| WO2000020410A1 (de) | 2000-04-13 |
| HK1040249B (zh) | 2005-04-01 |
| PL347105A1 (en) | 2002-03-25 |
| ZA200102589B (en) | 2002-02-27 |
| AU760412B2 (en) | 2003-05-15 |
| AU6192599A (en) | 2000-04-26 |
| HK1040249A1 (en) | 2002-05-31 |
| EP1117661B1 (de) | 2004-05-26 |
| CN1321154A (zh) | 2001-11-07 |
| KR100611030B1 (ko) | 2006-08-10 |
| DE59909609D1 (de) | 2004-07-01 |
| AR021843A1 (es) | 2002-08-07 |
| DK1117661T3 (da) | 2004-08-30 |
| ES2219065T3 (es) | 2004-11-16 |
| EP1117661A1 (de) | 2001-07-25 |
| BR9914266A (pt) | 2001-11-06 |
| DE19845402B4 (de) | 2005-04-07 |
| JP2002526539A (ja) | 2002-08-20 |
| KR20010103593A (ko) | 2001-11-23 |
| CN1150185C (zh) | 2004-05-19 |
| ATE267825T1 (de) | 2004-06-15 |
| RU2219176C2 (ru) | 2003-12-20 |
| PT1117661E (pt) | 2004-09-30 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| FD9A | Lapse of provisional protection due to non-payment of fees |