ZA200001357B - Method and apparatus for inactivation of biological contaminants using photosensitizers. - Google Patents

Method and apparatus for inactivation of biological contaminants using photosensitizers.

Info

Publication number
ZA200001357B
ZA200001357B ZA200001357A ZA200001357A ZA200001357B ZA 200001357 B ZA200001357 B ZA 200001357B ZA 200001357 A ZA200001357 A ZA 200001357A ZA 200001357 A ZA200001357 A ZA 200001357A ZA 200001357 B ZA200001357 B ZA 200001357B
Authority
ZA
South Africa
Prior art keywords
photosensitizers
inactivation
biological contaminants
contaminants
biological
Prior art date
Application number
ZA200001357A
Other languages
English (en)
Inventor
Raymond Paul Goodrich Jr
Frank Corbin Iii
Edward C Wood Jr
Dennis Hlavinka
Original Assignee
Gambro Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Gambro Inc filed Critical Gambro Inc
Publication of ZA200001357B publication Critical patent/ZA200001357B/xx

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61LMETHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L2/00Methods or apparatus for disinfecting or sterilising materials or objects other than foodstuffs or contact lenses; Accessories therefor
    • A61L2/0005Methods or apparatus for disinfecting or sterilising materials or objects other than foodstuffs or contact lenses; Accessories therefor for pharmaceuticals, biologicals or living parts
    • A61L2/0082Methods or apparatus for disinfecting or sterilising materials or objects other than foodstuffs or contact lenses; Accessories therefor for pharmaceuticals, biologicals or living parts using chemical substances
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61LMETHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L2/00Methods or apparatus for disinfecting or sterilising materials or objects other than foodstuffs or contact lenses; Accessories therefor
    • A61L2/0005Methods or apparatus for disinfecting or sterilising materials or objects other than foodstuffs or contact lenses; Accessories therefor for pharmaceuticals, biologicals or living parts
    • A61L2/0011Methods or apparatus for disinfecting or sterilising materials or objects other than foodstuffs or contact lenses; Accessories therefor for pharmaceuticals, biologicals or living parts using physical methods
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61LMETHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L2/00Methods or apparatus for disinfecting or sterilising materials or objects other than foodstuffs or contact lenses; Accessories therefor
    • A61L2/0005Methods or apparatus for disinfecting or sterilising materials or objects other than foodstuffs or contact lenses; Accessories therefor for pharmaceuticals, biologicals or living parts
    • A61L2/0011Methods or apparatus for disinfecting or sterilising materials or objects other than foodstuffs or contact lenses; Accessories therefor for pharmaceuticals, biologicals or living parts using physical methods
    • A61L2/0029Radiation
    • A61L2/0047Ultraviolet radiation
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61LMETHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L2/00Methods or apparatus for disinfecting or sterilising materials or objects other than foodstuffs or contact lenses; Accessories therefor
    • A61L2/0005Methods or apparatus for disinfecting or sterilising materials or objects other than foodstuffs or contact lenses; Accessories therefor for pharmaceuticals, biologicals or living parts
    • A61L2/0011Methods or apparatus for disinfecting or sterilising materials or objects other than foodstuffs or contact lenses; Accessories therefor for pharmaceuticals, biologicals or living parts using physical methods
    • A61L2/0029Radiation
    • A61L2/0052Visible light
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61LMETHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L2/00Methods or apparatus for disinfecting or sterilising materials or objects other than foodstuffs or contact lenses; Accessories therefor
    • A61L2/02Methods or apparatus for disinfecting or sterilising materials or objects other than foodstuffs or contact lenses; Accessories therefor using physical phenomena
    • A61L2/08Radiation
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61LMETHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L2/00Methods or apparatus for disinfecting or sterilising materials or objects other than foodstuffs or contact lenses; Accessories therefor
    • A61L2/02Methods or apparatus for disinfecting or sterilising materials or objects other than foodstuffs or contact lenses; Accessories therefor using physical phenomena
    • A61L2/08Radiation
    • A61L2/10Ultra-violet radiation
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61LMETHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L2/00Methods or apparatus for disinfecting or sterilising materials or objects other than foodstuffs or contact lenses; Accessories therefor
    • A61L2/16Methods or apparatus for disinfecting or sterilising materials or objects other than foodstuffs or contact lenses; Accessories therefor using chemical substances
    • A61L2/23Solid substances, e.g. granules, powders, blocks, tablets
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M1/00Suction or pumping devices for medical purposes; Devices for carrying-off, for treatment of, or for carrying-over, body-liquids; Drainage systems
    • A61M1/36Other treatment of blood in a by-pass of the natural circulatory system, e.g. temperature adaptation, irradiation ; Extra-corporeal blood circuits
    • A61M1/3616Batch-type treatment
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M1/00Suction or pumping devices for medical purposes; Devices for carrying-off, for treatment of, or for carrying-over, body-liquids; Drainage systems
    • A61M1/36Other treatment of blood in a by-pass of the natural circulatory system, e.g. temperature adaptation, irradiation ; Extra-corporeal blood circuits
    • A61M1/3621Extra-corporeal blood circuits
    • A61M1/3622Extra-corporeal blood circuits with a cassette forming partially or totally the blood circuit
    • A61M1/36222Details related to the interface between cassette and machine
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M1/00Suction or pumping devices for medical purposes; Devices for carrying-off, for treatment of, or for carrying-over, body-liquids; Drainage systems
    • A61M1/36Other treatment of blood in a by-pass of the natural circulatory system, e.g. temperature adaptation, irradiation ; Extra-corporeal blood circuits
    • A61M1/3621Extra-corporeal blood circuits
    • A61M1/3622Extra-corporeal blood circuits with a cassette forming partially or totally the blood circuit
    • A61M1/36224Extra-corporeal blood circuits with a cassette forming partially or totally the blood circuit with sensing means or components thereof
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M1/00Suction or pumping devices for medical purposes; Devices for carrying-off, for treatment of, or for carrying-over, body-liquids; Drainage systems
    • A61M1/36Other treatment of blood in a by-pass of the natural circulatory system, e.g. temperature adaptation, irradiation ; Extra-corporeal blood circuits
    • A61M1/3621Extra-corporeal blood circuits
    • A61M1/3622Extra-corporeal blood circuits with a cassette forming partially or totally the blood circuit
    • A61M1/36226Constructional details of cassettes, e.g. specific details on material or shape
    • A61M1/362263Details of incorporated filters
    • A61M1/362264Details of incorporated filters the filter being a blood filter
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M1/00Suction or pumping devices for medical purposes; Devices for carrying-off, for treatment of, or for carrying-over, body-liquids; Drainage systems
    • A61M1/36Other treatment of blood in a by-pass of the natural circulatory system, e.g. temperature adaptation, irradiation ; Extra-corporeal blood circuits
    • A61M1/3621Extra-corporeal blood circuits
    • A61M1/3622Extra-corporeal blood circuits with a cassette forming partially or totally the blood circuit
    • A61M1/36226Constructional details of cassettes, e.g. specific details on material or shape
    • A61M1/362266Means for adding solutions or substances to the blood
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M1/00Suction or pumping devices for medical purposes; Devices for carrying-off, for treatment of, or for carrying-over, body-liquids; Drainage systems
    • A61M1/36Other treatment of blood in a by-pass of the natural circulatory system, e.g. temperature adaptation, irradiation ; Extra-corporeal blood circuits
    • A61M1/3681Other treatment of blood in a by-pass of the natural circulatory system, e.g. temperature adaptation, irradiation ; Extra-corporeal blood circuits by irradiation
    • A61M1/3683Other treatment of blood in a by-pass of the natural circulatory system, e.g. temperature adaptation, irradiation ; Extra-corporeal blood circuits by irradiation using photoactive agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00Drugs for disorders of the blood or the extracellular fluid
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N7/00Viruses; Bacteriophages; Compositions thereof; Preparation or purification thereof
    • C12N7/04Inactivation or attenuation; Producing viral sub-units
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61LMETHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L2202/00Aspects relating to methods or apparatus for disinfecting or sterilising materials or objects
    • A61L2202/20Targets to be treated
    • A61L2202/22Blood or products thereof

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • Engineering & Computer Science (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Vascular Medicine (AREA)
  • Biomedical Technology (AREA)
  • Chemical & Material Sciences (AREA)
  • Epidemiology (AREA)
  • Hematology (AREA)
  • Medicinal Chemistry (AREA)
  • Cardiology (AREA)
  • Anesthesiology (AREA)
  • Molecular Biology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Organic Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Wood Science & Technology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Zoology (AREA)
  • Genetics & Genomics (AREA)
  • Biochemistry (AREA)
  • Microbiology (AREA)
  • Biotechnology (AREA)
  • Virology (AREA)
  • General Engineering & Computer Science (AREA)
  • Immunology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Diabetes (AREA)
  • Apparatus For Disinfection Or Sterilisation (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • External Artificial Organs (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
ZA200001357A 1998-07-21 2000-03-16 Method and apparatus for inactivation of biological contaminants using photosensitizers. ZA200001357B (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US09/119,666 US6258577B1 (en) 1998-07-21 1998-07-21 Method and apparatus for inactivation of biological contaminants using endogenous alloxazine or isoalloxazine photosensitizers

Publications (1)

Publication Number Publication Date
ZA200001357B true ZA200001357B (en) 2000-10-17

Family

ID=22385632

Family Applications (1)

Application Number Title Priority Date Filing Date
ZA200001357A ZA200001357B (en) 1998-07-21 2000-03-16 Method and apparatus for inactivation of biological contaminants using photosensitizers.

Country Status (5)

Country Link
US (1) US6258577B1 (US06258577-20010710-M00005.png)
EP (1) EP1047458B1 (US06258577-20010710-M00005.png)
BR (1) BR9906622A (US06258577-20010710-M00005.png)
WO (1) WO2000004930A2 (US06258577-20010710-M00005.png)
ZA (1) ZA200001357B (US06258577-20010710-M00005.png)

Families Citing this family (72)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20030194433A1 (en) * 2002-03-12 2003-10-16 Ecolab Antimicrobial compositions, methods and articles employing singlet oxygen- generating agent
US20040055965A1 (en) * 1997-06-13 2004-03-25 Hubig Stephan M. Recreational water treatment employing singlet oxygen
US7049110B2 (en) * 1998-07-21 2006-05-23 Gambro, Inc. Inactivation of West Nile virus and malaria using photosensitizers
US7186543B1 (en) * 1998-07-21 2007-03-06 Gambro Inc. Preparation of vaccines using a photosensitizer and light
US7094378B1 (en) * 2000-06-15 2006-08-22 Gambro, Inc. Method and apparatus for inactivation of biological contaminants using photosensitizers
US6268120B1 (en) * 1999-10-19 2001-07-31 Gambro, Inc. Isoalloxazine derivatives to neutralize biological contaminants
US7470245B2 (en) * 2000-02-02 2008-12-30 Xepmed, Inc. Extracorporeal pathogen reduction system
US7648699B2 (en) 2000-06-02 2010-01-19 Caridianbct Biotechnologies, Llc Preventing transfusion related complications in a recipient of a blood transfusion
TW590780B (en) * 2000-06-02 2004-06-11 Gambro Inc Additive solutions containing riboflavin
US7985588B2 (en) 2000-06-02 2011-07-26 Caridianbct Biotechnologies, Llc Induction of and maintenance of nucleic acid damage in pathogens using riboflavin and light
US6843961B2 (en) * 2000-06-15 2005-01-18 Gambro, Inc. Reduction of contaminants in blood and blood products using photosensitizers and peak wavelengths of light
US9044523B2 (en) 2000-06-15 2015-06-02 Terumo Bct, Inc. Reduction of contaminants in blood and blood products using photosensitizers and peak wavelengths of light
US20020015662A1 (en) * 2000-06-15 2002-02-07 Hlavinka Dennis J. Inactivation of contaminants using photosensitizers and pulsed light
DE10031851B4 (de) * 2000-07-04 2005-10-13 Blutspendedienst der Landesverbände des Deutschen Roten Kreuzes Niedersachsen, Sachsen-Anhalt, Thüringen, Oldenburg und Bremen gGmbH Photodynamische Behandlung und UV-B-Bestrahlung einer Thrombozyten-Suspension
DE10046267A1 (de) * 2000-09-19 2002-03-28 Bayer Ag Verwendung von Riboflavin und Flavinderivaten als Inhibitoren von Chitinasen
AU2001296309A1 (en) * 2000-09-27 2002-04-08 Gambro, Inc Inactivation of contaminants using photosensitizers and pulsed light
US7381976B2 (en) * 2001-03-13 2008-06-03 Triton Thalassic Technologies, Inc. Monochromatic fluid treatment systems
US20030147770A1 (en) * 2001-05-17 2003-08-07 Purepulse Technologies, Inc. Light treatment monitoring and data collection in a fluid treatment system using light for the treatment of fluid products
JP2004533318A (ja) * 2001-05-17 2004-11-04 ピュアパルス テクノロジーズ インコーポレイテッド 光を使用して流体製品を処理するシステムに関する方法および装置
US20030060747A1 (en) * 2001-05-17 2003-03-27 Fries William M. Fluid flow path for a fluid treatment system using light for the decontamination of fluid products
US20030030011A1 (en) * 2001-05-17 2003-02-13 Purepulse Technologies, Inc. Light treatment control in a fluid treatment system using light for the treatment of fluid products
JP2004520448A (ja) * 2001-05-30 2004-07-08 ガンブロ、 インコーポレイテッド 酸化防止剤を使用するウイルスの不活性化法
US20030228564A1 (en) * 2001-05-30 2003-12-11 Edrich Richard Alan Nitric oxide in a pathogen inactivation process
US20030141260A1 (en) * 2001-12-28 2003-07-31 Frank Corbin Oxygen-enhanced pathogen inactivation
US20030077264A1 (en) * 2001-09-20 2003-04-24 Goodrich Laura L. Antimicrobial blood treatment using allicin and related compounds
US20030086817A1 (en) * 2001-11-06 2003-05-08 Horton Isaac B. Blood purification system
US7264608B2 (en) * 2001-12-05 2007-09-04 Fenwal, Inc. Manual processing systems and methods for providing blood components conditioned for pathogen inactivation
AU2002366708A1 (en) * 2001-12-20 2003-07-09 Gambro, Inc. Preparation of vaccines using photosensitizer and light
WO2003063902A2 (en) * 2002-02-01 2003-08-07 Gambro, Inc. Inactivation of west nile virus and plasmodium falciparum using alloxazine-derivating photosensitizers
CA2474242C (en) * 2002-02-01 2011-05-17 Gambro, Inc. Reduction of contaminants in blood and blood products using photosensitizers and peak wavelengths of light
WO2003066109A1 (en) * 2002-02-08 2003-08-14 Gambro, Inc. Nitric oxide in a pathogen inactivation process
US20070020300A1 (en) * 2002-03-12 2007-01-25 Ecolab Inc. Recreational water treatment employing singlet oxygen
JP2005519744A (ja) 2002-03-14 2005-07-07 バクスター・インターナショナル・インコーポレイテッド 化合物除去器
CA2482021C (en) * 2002-04-24 2007-06-19 Gambro, Inc. Removal of adenine during a process of pathogen reducing blood and blood components
WO2003090794A1 (en) * 2002-04-26 2003-11-06 Gambro, Inc. Solution containing platelet activation inhibitors for pathogen reducing and storing blood platelets
JP2005523746A (ja) * 2002-04-26 2005-08-11 ガンブロ  インコーポレーテッド コンテナ内の流体を照射及び混合するための装置並びに方法
AU2003232031A1 (en) * 2002-05-03 2003-11-17 Gambro, Inc. Fluid mixing and irradiation device and method of using the device especially for biological fluids
EP1503806A1 (en) * 2002-05-06 2005-02-09 Gambro, Inc. Method for preventing damage to or rejuvenating a cellular blood component using mitochondrial enhancer
WO2004043338A2 (en) * 2002-05-10 2004-05-27 The Ohio State University Flavin n-oxides: new anti-cancer agents and pathogen eradication agents
EP1530571B1 (en) * 2002-08-23 2011-01-19 CaridianBCT Biotechnologies, LLC Nucleic acid damage using riboflavin and light
US20090023130A1 (en) * 2003-02-28 2009-01-22 Caridianbct Biotechnologies, Llc Prevention of Transfusion Related Acute Lung Injury Using Riboflavin and Light
US7534348B2 (en) * 2003-09-12 2009-05-19 Fenwal, Inc. Flow-through removal device and system using such device
US20050137517A1 (en) * 2003-12-19 2005-06-23 Baxter International Inc. Processing systems and methods for providing leukocyte-reduced blood components conditioned for pathogen inactivation
US7384558B2 (en) * 2004-07-26 2008-06-10 Baxter International Inc. Compositions capable of inhibiting reactive oxygen and carbonyl species
US7993580B2 (en) 2004-08-24 2011-08-09 Baxter International Inc. Methods for the inactivation of microorganisms in biological fluids, flow through reactors and methods of controlling the light sum dose to effectively inactivate microorganisms in batch reactors
CN100420490C (zh) * 2005-04-13 2008-09-24 刘余厚 全自动紫外线照射充氧自血回输处理方法及设备
US20070025918A1 (en) * 2005-07-28 2007-02-01 General Electric Company Magnetic resonance imaging (MRI) agents: water soluble carbon-13 enriched fullerene and carbon nanotubes for use with dynamic nuclear polarization
GB0515550D0 (en) 2005-07-29 2005-09-07 Univ Strathclyde Inactivation of staphylococcus species
US20070102858A1 (en) * 2005-11-07 2007-05-10 Navigant Biotechnologies, Inc. Clamps and methods for displacing fluid from portions of fluid containers
US8044051B2 (en) * 2006-01-27 2011-10-25 Caridianbct Biotechnologies, Llc Methods and compositions for the production of high concentration alloxazine solutions
US8016736B2 (en) * 2006-10-20 2011-09-13 Caridianbct Biotechnologies, Llc Methods for washing a red blood cell component and for removing prions therefrom
WO2008095148A2 (en) * 2007-01-31 2008-08-07 Sunstorm Research Corporation Methods and compositions for generation of reactive oxygen species
US20080234622A1 (en) * 2007-03-20 2008-09-25 Gambro Bct Inc. Methods and Systems for Preparing Blood Products
WO2009005853A1 (en) * 2007-07-02 2009-01-08 Caridianbct Biotechnologies, Llc Apparatus for photo reduction of contaminants in blood and blood products with calibration means
AU2008282232A1 (en) 2007-08-01 2009-02-05 Terumo Bct Biotechnologies, Llc. Pathogen inactivation of whole blood
US20100190676A1 (en) * 2008-07-22 2010-07-29 Ecolab Inc. Composition for enhanced removal of blood soils
WO2010132167A1 (en) * 2009-05-11 2010-11-18 Caridianbct Biotechnologies, Llc Stable calibration means for apparatus for photo reduction of contaminants in blood
US8715920B2 (en) 2010-07-27 2014-05-06 Biovec Transfusion, Llc Composition for preserving platelets during photosensitization
WO2012142180A1 (en) * 2011-04-12 2012-10-18 Tianxin Wang Methods to detect and treat diseases
DE102011105653A1 (de) * 2011-06-22 2012-12-27 TriOpto Tec GmbH 10H-Benzo[g]pteridin-2,4-dion-Derivate, Verfahren zur Herstellung und Verwendung derselben
DE102011105660A1 (de) * 2011-06-22 2012-12-27 TriOpto Tec GmbH Verwendung von 10H-Benzo[g]pteridin-2,4-dion-Derivaten
US8940228B2 (en) 2012-01-11 2015-01-27 Terumo Bct, Inc. Slidable clamp for port isolation
WO2013152253A1 (en) 2012-04-05 2013-10-10 Terumo Bct, Inc. Syestem and method for collecting and treating plasma protein fractions
US20140127077A1 (en) 2012-11-05 2014-05-08 Gail Rock Device and method for sterilization of instruments and surfaces
WO2015191599A2 (en) 2014-06-09 2015-12-17 Terumo Bct, Inc. Lyophilization
US10858643B2 (en) 2015-10-30 2020-12-08 Sensor Electronic Technology, Inc. Vaccine preparation using ultraviolet radiation
CA3025799A1 (en) 2016-05-27 2017-11-30 Bloodworks Methods of preventing platelet alloimmunization and alloimmune platelet refractoriness and induction of tolerance in transfused recipients
EP3746151B1 (en) 2018-02-28 2024-04-24 Plas-Free Ltd. Extracorporeal device and matrix for removing fibrinolytic proteins from biological fluids, methods and uses thereof
FR3088076B1 (fr) * 2018-11-05 2022-11-11 Sterixene Bio-indicateur de decontamination a lumiere pulsee haute frequence
EP3725334A1 (de) * 2019-04-16 2020-10-21 HUBL GmbH Edelstahltechnik Vorrichtung und verfahren zur reduzierung der anzahl von keimen
US11364330B2 (en) 2020-11-10 2022-06-21 Alfredo R. Zarate System and method for facilitating extracorporeal inactivation of pathogens of blood products
US11458220B2 (en) 2020-11-12 2022-10-04 Singletto Inc. Microbial disinfection for personal protection equipment

Family Cites Families (196)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US683690A (en) 1900-06-13 1901-10-01 Charles M Johnson Apparatus for sterilizing disease-germs.
US1733239A (en) 1929-01-31 1929-10-29 Donald E Roberts Applicator for conducting ultra-violet rays
US1961700A (en) 1932-07-29 1934-06-05 Gen Electric Vapor Lamp Co Apparatus for sterilizing articles by ultraviolet radiation
US2056614A (en) 1933-06-13 1936-10-06 Gen Electric Vapor Lamp Co Ultraviolet sterilizer
US2212330A (en) 1938-05-03 1940-08-20 Albert G Thomas Sterilizing device
US2212230A (en) 1938-05-28 1940-08-20 Internat Telephone Dev Co Inc Airplane guiding beacon
US2340890A (en) 1941-02-25 1944-02-08 Lang Alphonse Method and apparatus for sterilizing, preserving, and irradiating of various liquid substances
US3456053A (en) 1966-05-06 1969-07-15 Pfizer & Co C Inactivated hog cholera virus vaccine
US3683183A (en) 1969-06-04 1972-08-08 Radiation Machinery Corp A flow-through irradiator for the extra corporeal irradiation of fluid
US3705985A (en) 1969-06-27 1972-12-12 Nuclear Associates Inc Fluid irradiator and process for its manufacture
US3683177A (en) 1970-06-30 1972-08-08 Louis P Veloz Sterilization of a fluid by ultraviolet radiation
US3852032A (en) 1971-06-07 1974-12-03 Uroptics Int Inc Process for sterilizing hydrophilic gelatin lenses having ultraviolet stabilizers
US3776694A (en) 1972-04-04 1973-12-04 L Leittl Germicidal toiletry cabinet for different personal hygiene items
US3926556A (en) 1973-05-30 1975-12-16 Raymond Marcel Gut Boucher Biocidal electromagnetic synergistic process
US3864081A (en) 1973-06-12 1975-02-04 Spectroderm International Inc Apparatus for sterilizing biologic material and the like by ultra-violet irradiation
US3894236A (en) 1973-12-10 1975-07-08 Wayne K Hazelrigg Device for irradiating fluids
US3927325A (en) 1974-07-10 1975-12-16 Us Energy Tissue irradiator
US4305390A (en) 1975-11-28 1981-12-15 Massachusetts Institute Of Technology Method for generating oxygen in an excited electronic state and inactivation of microorganisms
US4181128A (en) 1975-11-28 1980-01-01 Massachusetts Institute Of Technology Virus inactivation applicator and the like
US4139348A (en) 1975-11-28 1979-02-13 Massachusetts Institute Of Technology Electrochemical process and apparatus to control the chemical state of a material
US4124598A (en) 1976-10-20 1978-11-07 Hoffmann-La Roche Inc. Psoralens
US4169204A (en) 1976-10-20 1979-09-25 Regents Of The University Of California Psoralens
US4196281A (en) 1976-10-20 1980-04-01 Regents Of The University Of California Psoralens
US4424201A (en) 1978-11-28 1984-01-03 Rockefeller University Employment of a mereyanine dye for the detection of malignant leukocytic cells
IT1166343B (it) 1979-08-20 1987-04-29 Francarosa Baccichetti Furocumarina per la fotochemioterapia della fsoriasi e di altre malattie cutanee ad essa sensibili
US4321918A (en) 1979-10-23 1982-03-30 Clark Ii William T Process for suppressing immunity to transplants
US4428744A (en) 1979-12-11 1984-01-31 Frederic A. Bourke, Jr. Method and system for externally treating the blood
US4398906A (en) 1979-12-11 1983-08-16 Frederic A. Bourke, Jr. Method for externally treating the blood
US4321919A (en) 1979-12-11 1982-03-30 Leukocyte Research, Inc. Method and system for externally treating human blood
US4336809A (en) 1980-03-17 1982-06-29 Burleigh Instruments, Inc. Human and animal tissue photoradiation system and method
DE8007265U1 (de) 1980-03-17 1981-08-27 ESPE Fabrik pharmazeutischer Präparate GmbH, 8031 Seefeld Geraet zum behandeln von zahnersatzteilen
US4481167A (en) 1980-04-11 1984-11-06 The Dow Chemical Company Sanitizing complexes of polyoxazolines or polyoxazines and polyhalide anions
US4398031A (en) 1980-06-11 1983-08-09 The Regents Of The University Of California Coumarin derivatives and method for synthesizing 5'-methyl psoralens therefrom
JPS616899Y2 (US06258577-20010710-M00005.png) 1981-04-27 1986-03-03
US4568542A (en) 1981-06-09 1986-02-04 Lee Biomolecular Research Laboratories, Inc. Vaccine compositions
US4464166A (en) 1981-06-12 1984-08-07 Frederic A. Bourke, Jr. Method for externally treating the blood
US4612007A (en) 1981-06-16 1986-09-16 Edelson Richard Leslie Method and system for externally treating the blood
EP0087441A1 (en) 1981-09-08 1983-09-07 Quentron Optics Pty. Ltd. Photoradiation method and arrangement
JPS5862333A (ja) 1981-10-09 1983-04-13 Mazda Motor Corp エンジンのアイドル回転制御装置
US4467206A (en) 1981-12-14 1984-08-21 Extracorporeal Medical Specialties, Inc. Method and apparatus for the irradiation of fluids
US4456512A (en) 1982-03-10 1984-06-26 The Dow Chemical Company Photochemical reactor and method
US4649151A (en) 1982-09-27 1987-03-10 Health Research, Inc. Drugs comprising porphyrins
CA1216518A (en) 1982-11-01 1987-01-13 Gail A. Rock Plasma-free medium for platelet storage
US4684521A (en) 1982-12-08 1987-08-04 Frederic A. Bourke, Jr. Method and system for externally treating the blood
US4613322A (en) 1982-12-08 1986-09-23 Edelson Richard Leslie Method and system for externally treating the blood
US4683889A (en) 1983-03-29 1987-08-04 Frederic A. Bourke, Jr. Method and system for externally treating the blood
DE3483751D1 (de) 1983-05-02 1991-01-31 Diamond Scient Co Photochemische entkeimungsbehandlung von vollem blut oder blutbestandteilen.
US4727027A (en) 1983-05-02 1988-02-23 Diamond Scientific Co. Photochemical decontamination treatment of whole blood or blood components
US4748120A (en) 1983-05-02 1988-05-31 Diamond Scientific Co. Photochemical decontamination treatment of whole blood or blood components
US4946438A (en) 1983-09-01 1990-08-07 The Trustees Of Columbia University In The City Of New York Process for development of acceptance of transplanted organs and tissues
US4861704A (en) 1983-09-01 1989-08-29 The Trustees Of Columbia University In The City Of New York Processes for development of acceptance of transplanted organs and tissues
US4992363A (en) 1983-11-09 1991-02-12 Thomas Jefferson University Method for preparing glucose free media for storing blood platelets
US4693981A (en) 1983-12-20 1987-09-15 Advanced Genetics Research Institute Preparation of inactivated viral vaccines
US4604356A (en) 1983-12-21 1986-08-05 Miles Laboratories, Inc. Purification of flavin adenine dinucleotide synthetase
CH657864A5 (de) 1984-02-17 1986-09-30 Ciba Geigy Ag Wasserloesliche phthalocyaninverbindungen und deren verwendung als photoaktivatoren.
US4493981A (en) 1984-03-05 1985-01-15 General Electric Company Boil dry protection system for cooking appliance
US5550111A (en) 1984-07-11 1996-08-27 Temple University-Of The Commonwealth System Of Higher Education Dual action 2',5'-oligoadenylate antiviral derivatives and uses thereof
JPH0622222B2 (ja) 1984-09-18 1994-03-23 株式会社東芝 光処理装置
JPS6176160A (ja) 1984-09-21 1986-04-18 松永 是 殺細胞方法
US4576143A (en) 1984-10-05 1986-03-18 Clark Iii William T Method of immune modification by means of extracorporeal irradiation of the blood
US4708715A (en) 1984-10-29 1987-11-24 Mcneilab, Inc. Light array assembly for photoactivation patient treatment system
US4573962A (en) 1984-10-29 1986-03-04 Extracorporeal Medical Specialties, Inc. Cassette drawer assembly for photoactivation patient treatment system
US4568328A (en) 1984-10-29 1986-02-04 Extracorporeal Medical Specialties, Inc. Automated photophoresis blood portion control methods and apparatus
US4596547A (en) 1984-10-29 1986-06-24 Mcneilab, Inc. Valve apparatus for photoactivation patient treatment system
US4573961A (en) 1984-10-29 1986-03-04 Extracorporeal Medical Specialties, Inc. Electronic control methods for puvapheresis apparatus
US4737140A (en) 1984-10-29 1988-04-12 Mcneilab, Inc. Irradiation chamber for photoactivation patient treatment system
US4623328A (en) 1984-10-29 1986-11-18 Mcneilab, Inc. Pump monitor for photoactivation patient treatment system
US4578056A (en) 1984-10-29 1986-03-25 Extracorporeal Medical Specialties, Inc. Patient photopheresis treatment apparatus and method
US4573960A (en) 1984-10-29 1986-03-04 Extracorporeal Medical Specialties, Inc. Three phase irradiation treatment process
US4608255A (en) 1985-01-31 1986-08-26 American National Red Cross Biocompatible method for in situ production of functional platelets and product produced thereby lacking immunogenicity
JPS61275228A (ja) * 1985-03-14 1986-12-05 バクスタ−、トラベノ−ル、ラボラトリ−ズ、インコ−ポレイテツド 治療用タンパク組成物中のビ−ルスの光動的不活性化
DD249143A3 (de) 1985-03-20 1987-09-02 Ilmenau Tech Hochschule Vorrichtung zur physiologisch-therapeutisch wirksamen optischen bestrahlung koerpereigenen venenblutes
US4683195A (en) 1986-01-30 1987-07-28 Cetus Corporation Process for amplifying, detecting, and/or-cloning nucleic acid sequences
US4683202A (en) 1985-03-28 1987-07-28 Cetus Corporation Process for amplifying nucleic acid sequences
US4651739A (en) 1985-04-08 1987-03-24 The General Hospital Corporation Light-induced killing of carcinoma cells
US4998931A (en) 1985-07-05 1991-03-12 Puget Sound Blood Center Method of reducing immunogenicity and inducing immunologic tolerance
US4930516B1 (en) 1985-11-13 1998-08-04 Laser Diagnostic Instr Inc Method for detecting cancerous tissue using visible native luminescence
US4695460A (en) 1986-03-19 1987-09-22 American Red Cross Synthetic, plasma-free, transfusible platelet storage medium
US4961928A (en) 1986-03-19 1990-10-09 American Red Cross Synthetic, plasma-free, transfusible storage medium for red blood cells and platelets
US5248506A (en) 1986-03-19 1993-09-28 American National Red Cross Synthetic, plasma-free, transfusible storage medium for red blood cells and platelets
US5017338A (en) 1986-04-11 1991-05-21 The Center For Blood Research, Inc. Platelet concentrates
US4952812A (en) 1986-08-26 1990-08-28 Baxter International Inc. Irradiation of blood products
US4726949A (en) 1986-08-26 1988-02-23 Baxter Travenol Laboratories, Inc. Irradiation of blood products
US4866282A (en) 1986-08-26 1989-09-12 Baxter International Inc. Irradiation of blood products
US4775625A (en) 1986-11-21 1988-10-04 The Medical College Of Wisconsin, Inc. Inactivating enveloped viruses with a merocyanine dye
US4915683A (en) 1986-11-21 1990-04-10 The Medical College Of Wisconsin, Inc. Antiviral method, agents and apparatus
US5039483A (en) 1987-03-10 1991-08-13 The Medical College Of Wisconsin, Inc. Antiprotozoan method
US5304113A (en) 1986-11-21 1994-04-19 The Mcw Research Foundation, Inc. Method of eradicating infectious biological contaminants
US4878891A (en) 1987-06-25 1989-11-07 Baylor Research Foundation Method for eradicating infectious biological contaminants in body tissues
US4833165A (en) 1987-10-07 1989-05-23 Louderback Allan Lee Method of inactivating HTLV-III virus in blood
JPH01207070A (ja) 1987-10-22 1989-08-21 Jr Robert E Duthie 滅菌方法および装置
US4880788A (en) 1987-10-30 1989-11-14 Baylor College Of Medicine Method for preventing and treating thrombosis
US5229081A (en) 1988-02-12 1993-07-20 Regal Joint Co., Ltd. Apparatus for semiconductor process including photo-excitation process
DE3805459A1 (de) 1988-02-22 1989-08-31 Biotest Pharma Gmbh Verfahren zur sterilisation von blut, plasma, blut- und plasmaderivaten, zellsuspensionen oder dgl.
GB8807380D0 (en) 1988-03-29 1988-05-05 Gunn A Blood processing apparatus
US5288647A (en) 1988-05-02 1994-02-22 Stratagene Method of irradiating biological specimens
DE3824647A1 (de) 1988-07-20 1990-02-01 Wedeco Entkeimungsanlagen Vorrichtung zur bestrahlung von medien mittels uv-licht
WO1990001563A1 (en) 1988-08-01 1990-02-22 Cimino George D Identification of allele specific nucleic acid sequences by hybridization with crosslinkable oligonucleotide probes
WO1990002353A1 (en) 1988-08-23 1990-03-08 Radiotekhnichesky Institut Imeni Akademika A.L.Mintsa Akademii Nauk Sssr Light-guiding device for medical treatment
DE3831141A1 (de) 1988-09-13 1990-03-22 Zeiss Carl Fa Verfahren und vorrichtung zur mikrochirurgie am auge mittels laserstrahlung
US4994367A (en) 1988-10-07 1991-02-19 East Carolina University Extended shelf life platelet preparations and process for preparing the same
US4950665A (en) 1988-10-28 1990-08-21 Oklahoma Medical Research Foundation Phototherapy using methylene blue
US5571666A (en) 1988-10-28 1996-11-05 Oklahoma Medical Research Foundation Thiazine dyes used to inactivate HIV in biological fluids
US5089384A (en) 1988-11-04 1992-02-18 Amoco Corporation Method and apparatus for selective cell destruction using amplified immunofluorescence
US5419759A (en) 1988-11-17 1995-05-30 Naficy; Sadeque S. Apparatus and methods for treatment of HIV infections and AIDS
US5020995A (en) 1989-01-18 1991-06-04 Guy Levy Surgical treatment method and instrument
US5092773A (en) 1989-01-18 1992-03-03 Endo Technic Corporation Method and apparatus for filling a tooth canal
US4960408A (en) 1989-01-10 1990-10-02 Klainer Albert S Treatment methods and vaccines for stimulating an immunological response against retroviruses
US5273713A (en) 1989-01-18 1993-12-28 Laser Medical Technology, Inc. Water purification and sterilization process
US4921473A (en) 1989-02-02 1990-05-01 Therakos, Inc. Multicomponent fluid separation and irradiation system
US5041078A (en) 1989-03-06 1991-08-20 Baylor Research Foundation, A Nonprofit Corporation Of The State Of Texas Photodynamic viral deactivation with sapphyrins
US4978688A (en) 1989-03-24 1990-12-18 Louderback Allan Lee Method of treating white blood cells
US4999375A (en) 1989-04-11 1991-03-12 Hoffmann-La Roche Inc. Psoralen reagent compositions for extracorporeal treatment of blood
US5150705A (en) 1989-07-12 1992-09-29 Stinson Randy L Apparatus and method for irradiating cells
MY108087A (en) 1989-07-12 1996-08-15 Randy L Stinson Apparatus and method for irradiating cells.
US5366440A (en) 1989-10-06 1994-11-22 The Beth Israel Hospital Association Methods for treating disease states using oxidized lipoproteins in conjunction with chemotherapeutic effector agents
US5192264A (en) 1989-10-06 1993-03-09 The Beth Israel Hospital Association Methods and apparatus for treating disease states using oxidized lipoproteins
US5556958A (en) 1989-10-26 1996-09-17 Steritech, Inc. Inactivation of pathogens in clinical samples
US5184020A (en) 1989-10-26 1993-02-02 Hearst David P Device and method for photoactivation
US5503721A (en) 1991-07-18 1996-04-02 Hri Research, Inc. Method for photoactivation
US5236716A (en) 1990-02-12 1993-08-17 Miles Inc. Platelets concentrate with low white blood cells content
US5089146A (en) 1990-02-12 1992-02-18 Miles Inc. Pre-storage filtration of platelets
US5147776A (en) 1990-02-26 1992-09-15 University Of Iowa Research Foundation Use of 2,5-anhydromannitol for control of pH during blood storage
US5587490A (en) 1990-04-16 1996-12-24 Credit Managers Association Of California Method of inactivation of viral and bacterial blood contaminants
US5342752A (en) 1990-04-16 1994-08-30 Cryopharm Corporation Method of inactivation of viral blood contaminants using acridine deriatives
US5516629A (en) 1990-04-16 1996-05-14 Cryopharm Corporation Photoinactivation of viral and bacterial blood contaminants using halogenated coumarins
US5798238A (en) 1990-04-16 1998-08-25 Baxter International Inc. Method of inactivation of viral and bacterial blood contaminants with quinolines as photosensitizer
US5418130A (en) 1990-04-16 1995-05-23 Cryopharm Corporation Method of inactivation of viral and bacterial blood contaminants
US5545516A (en) 1990-05-01 1996-08-13 The American National Red Cross Inactivation of extracellular enveloped viruses in blood and blood components by phenthiazin-5-ium dyes plus light
US5114957A (en) 1990-05-08 1992-05-19 Biodor U.S. Holding Tocopherol-based antiviral agents and method of using same
US5232844A (en) 1990-05-15 1993-08-03 New York Blood Center Photodynamic inactivation of viruses in cell-containing compositions
US5712086A (en) 1990-05-15 1998-01-27 New York Blood Center, Inc. Process for transfusing cell containing fractions sterilized with radiation and a quencher of type I and type II photodynamic reactions
US5658722A (en) 1990-05-15 1997-08-19 New York Blood Center, Inc. Process for the sterilization of biological compositions using UVA1 irradiation
US5120649A (en) 1990-05-15 1992-06-09 New York Blood Center, Inc. Photodynamic inactivation of viruses in blood cell-containing compositions
DE4017091A1 (de) 1990-05-27 1991-11-28 Walter Dr Mach Molekuelverbundsystem zur kontra-eskalativen therapie viraler infektionskrankheiten
US5114670A (en) 1990-08-30 1992-05-19 Liqui-Box/B-Bar-B Corporation Process for sterilizing surfaces
CA2075704A1 (en) 1990-12-20 1992-06-21 Daniel F. Bischof Systems and methods eradicating contaminants in fluids
AU648631B2 (en) 1990-12-20 1994-04-28 Baxter International Inc. Systems and methods for simultaneously removing free and entrained contaminants in fluids like blood using photoactive therapy and cellular separation techniques
CA2074806A1 (en) 1990-12-20 1992-06-21 Ludwig Wolf Jr. Systems for eradicating contaminants in fluids
US5376524A (en) 1991-04-01 1994-12-27 Thomas Jefferson University Platelet storage medium containing acetate and phosphate
US5569579A (en) 1991-04-01 1996-10-29 Thomas Jefferson University Synthetic-based platelet storage media
FR2715303A1 (fr) 1991-04-02 1995-07-28 Berque Jean Utilisation du FAD et/ou du NAD comme médicaments.
FR2674753B1 (fr) 1991-04-02 1995-03-10 Jean Berque Nouvelles indications therapeutiques, en particulier pour le traitement du sida, d'un medicament deja existant et fabrique a partir d'une molecule denuee de contre-indications et d'effets indesirables.
US5318023A (en) 1991-04-03 1994-06-07 Cedars-Sinai Medical Center Apparatus and method of use for a photosensitizer enhanced fluorescence based biopsy needle
US5185532A (en) 1991-05-21 1993-02-09 Oral Card Products Dental instrument sterilizer
US5269946A (en) 1991-05-22 1993-12-14 Baxter Healthcare Corporation Systems and methods for removing undesired matter from blood cells
US5340716A (en) 1991-06-20 1994-08-23 Snytex (U.S.A.) Inc. Assay method utilizing photoactivated chemiluminescent label
CA2089005C (en) 1991-06-21 1999-01-19 John Chapman Method for inactivating pathogens in a body fluid
US5166528A (en) 1991-10-04 1992-11-24 Le Vay Thurston C Microwave-actuated ultraviolet sterilizer
US5216251A (en) 1991-10-18 1993-06-01 Matschke Arthur L Apparatus and method for a bio-conditioning germicidal dryer
US5344752A (en) 1991-10-30 1994-09-06 Thomas Jefferson University Plasma-based platelet concentrate preparations
US5234808A (en) 1991-10-30 1993-08-10 Thomas Jefferson University Acetate addition to platelets stored in plasma
US5474891A (en) 1991-10-30 1995-12-12 Thomas Jefferson University Plasma-based platelet concentrate preparations with additive
US5258124A (en) 1991-12-06 1993-11-02 Solarchem Enterprises, Inc. Treatment of contaminated waste waters and groundwaters with photolytically generated hydrated electrons
US5247178A (en) 1991-12-12 1993-09-21 Fusion Systems Corporation Method and apparatus for treating fluids by focusing reflected light on a thin fluid layer
FR2684999A1 (fr) 1991-12-16 1993-06-18 Aquitaine Dev Transf Sanguine Procede de fabrication d'un concentre de facteur vii active de haute purete essentiellement depourvu des facteurs vitamine k dependants et des facteurs viiic et viiicag.
US5639382A (en) 1991-12-23 1997-06-17 Baxter International Inc. Systems and methods for deriving recommended storage parameters for collected blood components
US5607924A (en) 1992-01-21 1997-03-04 Pharmacyclics, Inc. DNA photocleavage using texaphyrins
US5288605A (en) 1992-03-02 1994-02-22 Steritech, Inc. Methods for inactivating bacteria in blood preparations with 8-methoxypsoralen
AU4677993A (en) 1992-08-07 1994-03-03 Steritech, Inc. Methods for inactivating bacteria in blood preparations with 8-methoxypsoralen
US5709991A (en) 1992-03-02 1998-01-20 Cerus Corporation Proralen inactivation of microorganisms and psoralen removal
US5459030A (en) 1992-03-02 1995-10-17 Steritech, Inc. Synthetic media compositions for inactivating bacteria and viruses in blood preparations with 8-methoxypsoralen
US5378601A (en) 1992-07-24 1995-01-03 Montefiore Medical Center Method of preserving platelets with apyrase and an antioxidant
FR2696319B1 (fr) * 1992-10-02 1994-12-30 Jean Berque Utilisation de produits biologiques atoxiques et principalement de la riboflavine dans la fabrication des préservatifs et des gants de protection médico-chirurgicaux.
US5597722A (en) 1993-01-28 1997-01-28 Baxter International Inc. Method for inactivating pathogens in compositions containing cells and plasma using photoactive compounds and plasma protein reduction
US5358844A (en) 1993-02-18 1994-10-25 Brigham And Women's Hospital, Inc. Preservation of blood platelets
US5686436A (en) 1993-05-13 1997-11-11 Hiv Diagnostics, Inc. Multi-faceted method to repress reproduction of latent viruses in humans and animals
US5593823A (en) 1993-06-28 1997-01-14 Cerus Corporation Method for inactivating pathogens in blood using photoactivation of 4'-primary amino-substituted psoralens
US5871900A (en) 1993-06-28 1999-02-16 Cerus Corporation Method of inactivating pathogens in biological fluids using photoactivated 5-primaryamino psoralens
US5399719A (en) 1993-06-28 1995-03-21 Steritech, Inc. Compounds for the photodecontamination of pathogens in blood
US5556993A (en) 1993-06-28 1996-09-17 Steritech, Inc. Compounds for the photodecontamination of pathogens in blood
EG20321A (en) 1993-07-21 1998-10-31 Otsuka Pharma Co Ltd Medical material and process for producing the same
US5427695A (en) 1993-07-26 1995-06-27 Baxter International Inc. Systems and methods for on line collecting and resuspending cellular-rich blood products like platelet concentrate
KR100332250B1 (ko) 1993-09-24 2002-12-05 이. 가브릴로프 알렉산더 2',5'-올리고아데닐레이트2',3'-시클로포스페이트
US5639376A (en) 1994-01-10 1997-06-17 Hemasure, Inc. Process for simultaneously removing leukocytes and methylene blue from plasma
IL108918A (en) 1994-03-10 1997-04-15 Medic Lightech Ltd Apparatus for efficient photodynamic treatment
FR2718353B3 (fr) 1994-04-11 1996-06-28 Jean Berque Compositions pharmaceutiques à base de produits biologiques atoxiques destinées à la protection locale des muqueuses génitales et rectales.
CN1069162C (zh) 1994-05-02 2001-08-08 诺尔科化学公司 用作改进的抗微生物剂的荧光杀生物剂组合物
DE4416166C2 (de) 1994-05-06 1997-11-20 Immuno Ag Stabiles Präparat zur Behandlung von Blutgerinnungsstörungen
WO1996009776A1 (en) 1994-09-27 1996-04-04 Purepulse Technologies, Inc. Photocatalyst and pulsed light synergism in deactivation of contaminants
US5622867A (en) 1994-10-19 1997-04-22 Lifecell Corporation Prolonged preservation of blood platelets
US5691132A (en) 1994-11-14 1997-11-25 Cerus Corporation Method for inactivating pathogens in red cell compositions using quinacrine mustard
US5527704A (en) 1994-12-06 1996-06-18 Baxter International Inc. Apparatus and method for inactivating viral contaminants in body fluids
US5557098A (en) 1994-12-20 1996-09-17 Baxter International Inc. System to identify bags disinfected by irradiation which punches holes in a polarized portion of the bag to indicate processing thereof
US5683768A (en) 1994-12-21 1997-11-04 Baxter International Inc. Plastic formulations for platelet storage containers and the like
US5643334A (en) 1995-02-07 1997-07-01 Esc Medical Systems Ltd. Method and apparatus for the diagnostic and composite pulsed heating and photodynamic therapy treatment
US5624435A (en) 1995-06-05 1997-04-29 Cynosure, Inc. Ultra-long flashlamp-excited pulse dye laser for therapy and method therefor
US5653887A (en) 1995-06-07 1997-08-05 Cobe Laboratories, Inc. Apheresis blood processing method using pictorial displays
US5714328A (en) 1995-06-07 1998-02-03 Board Of Regents, The University Of Texas System RNA photocleavage using texaphyrins
US5628727A (en) 1995-08-15 1997-05-13 Hakky; Said I. Extracorporeal virioncidal apparatus
DE69615996T2 (de) 1995-12-04 2002-04-04 Jms Co Ltd Behälter für medizinische Zwecke
US5843459A (en) 1996-01-19 1998-12-01 Human Gene Therapy Research Institute Differential inactivation of nucleic acids by chemical modification
US5834198A (en) * 1996-03-21 1998-11-10 Boehringer Mamnnheim Gmbh Selective photoinducted flavin-dependent cleavage of RNA at G-U base pairs and kits therefor
US5798523A (en) 1996-07-19 1998-08-25 Theratechnologies Inc. Irradiating apparatus using a scanning light source for photodynamic treatment
US5709653A (en) 1996-07-25 1998-01-20 Cordis Corporation Photodynamic therapy balloon catheter with microporous membrane
US5922278A (en) 1996-11-19 1999-07-13 Baxter International Inc. Method and apparatus for inactivating contaminants in biological fluid

Also Published As

Publication number Publication date
EP1047458B1 (en) 2011-06-08
US6258577B1 (en) 2001-07-10
BR9906622A (pt) 2001-12-18
EP1047458A2 (en) 2000-11-02
WO2000004930A2 (en) 2000-02-03
WO2000004930A3 (en) 2000-08-17

Similar Documents

Publication Publication Date Title
ZA200001357B (en) Method and apparatus for inactivation of biological contaminants using photosensitizers.
HUP0004907A3 (en) Method and apparatus for inactivation of biological contaminants using photosensitizers
AU5823498A (en) Method and apparatus for cleaning, decontaminating, and sterilizing catheters
HK1021157A1 (en) Waste treatment apparatus and method
AP2003002875A0 (en) Apparatus and method for treatment of water.
AU2577999A (en) Apparatus and method of food decontamination by treatment with ozone
AU8471798A (en) Method and apparatus for biological treatment of waste water
AU6945298A (en) Improved wastewater treatment apparatus and method
AU2001269735A1 (en) Method and apparatus for inactivation of biological contaminants using photosensitizers
AU3440999A (en) Method and apparatus for treating objects with ozone
AU2272400A (en) Method and apparatus for ozone sterilization
EP1101738A3 (en) Apparatus and method for waste water treatment
AU2442397A (en) Method and apparatus for treating and disinfecting water and/or wastewater
GB9807944D0 (en) Apparatus for wastewater treatment and method
HK1039774A1 (zh) 對液體進行淨化和消毒的方法和裝置
AU2369200A (en) Method and apparatus for sterile liquids
ZA9810814B (en) Apparatus and method for sterilising soil
AU3242301A (en) Device and method for sterilizing or disinfecting waste
GB9801808D0 (en) Apparatus and method for waste treatment
AU2002219307A1 (en) Method and apparatus for biological treatment of effluents
AU8998898A (en) Sludge or excreta treating agent, treating method, and treating apparatus
AU4053399A (en) Process and apparatus for the disinfection of medical waste
AU2716100A (en) Method and apparatus for infrared sterilization
ZA994748B (en) Aqueous solution for disinfecting apparatus and surfaces and method for such disinfection.
HK1056865A1 (en) Method and apparatus for the treatment of biological suspensions.