YU90403A - Naphtothiazine positive allosteric ampa receptor modulators (paarm) - Google Patents
Naphtothiazine positive allosteric ampa receptor modulators (paarm)Info
- Publication number
- YU90403A YU90403A YU90403A YUP90403A YU90403A YU 90403 A YU90403 A YU 90403A YU 90403 A YU90403 A YU 90403A YU P90403 A YUP90403 A YU P90403A YU 90403 A YU90403 A YU 90403A
- Authority
- YU
- Yugoslavia
- Prior art keywords
- receptor modulators
- paarm
- naphtothiazine
- positive allosteric
- ampa receptor
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D279/00—Heterocyclic compounds containing six-membered rings having one nitrogen atom and one sulfur atom as the only ring hetero atoms
- C07D279/02—1,2-Thiazines; Hydrogenated 1,2-thiazines
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/18—Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Public Health (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- Biomedical Technology (AREA)
- Neurosurgery (AREA)
- Neurology (AREA)
- Cardiology (AREA)
- Heart & Thoracic Surgery (AREA)
- Psychiatry (AREA)
- Urology & Nephrology (AREA)
- Hospice & Palliative Care (AREA)
- Vascular Medicine (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
- Nitrogen- Or Sulfur-Containing Heterocyclic Ring Compounds With Rings Of Six Or More Members (AREA)
Abstract
The present invention relates to new positive allosteric AMPA-receptor modulators of general formula (I), wherein R1, R2, R3, R4 and R5 may have the meanings given in the specification and claims, processes for preparing them and the use thereof as pharmaceutical compositions.
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
DE10123952A DE10123952A1 (en) | 2001-05-17 | 2001-05-17 | New naphtho-1,2-thiazine compounds, useful as neuroprotectants for treating e.g. epilepsy or Alzheimer's disease, are allosteric modulators of AMPA receptors |
Publications (1)
Publication Number | Publication Date |
---|---|
YU90403A true YU90403A (en) | 2006-05-25 |
Family
ID=7685080
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
YU90403A YU90403A (en) | 2001-05-17 | 2002-05-15 | Naphtothiazine positive allosteric ampa receptor modulators (paarm) |
Country Status (26)
Country | Link |
---|---|
EP (1) | EP1404340A1 (en) |
JP (1) | JP2004529980A (en) |
KR (1) | KR20040007572A (en) |
CN (1) | CN1533278A (en) |
AR (1) | AR036332A1 (en) |
BG (1) | BG108324A (en) |
BR (1) | BR0209796A (en) |
CA (1) | CA2449189A1 (en) |
CO (1) | CO5550460A2 (en) |
CZ (1) | CZ20033112A3 (en) |
DE (1) | DE10123952A1 (en) |
EA (1) | EA006608B1 (en) |
EC (1) | ECSP034852A (en) |
EE (1) | EE200300566A (en) |
HR (1) | HRP20030933A2 (en) |
HU (1) | HUP0401273A3 (en) |
IL (1) | IL158642A0 (en) |
MX (1) | MXPA03010373A (en) |
NO (1) | NO20035088D0 (en) |
NZ (1) | NZ530154A (en) |
PL (1) | PL364053A1 (en) |
SK (1) | SK14222003A3 (en) |
UY (1) | UY27290A1 (en) |
WO (1) | WO2002100411A1 (en) |
YU (1) | YU90403A (en) |
ZA (1) | ZA200308466B (en) |
Families Citing this family (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CA2660431C (en) * | 2006-08-31 | 2015-03-17 | The Governors Of The University Of Alberta | Method of inhibition of respiratory depression using positive allosteric ampa receptor modulators |
CN111518058B (en) * | 2020-05-29 | 2021-03-09 | 四川大学华西医院 | Oxathiazine compound and application thereof |
Family Cites Families (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
WO1998012185A1 (en) * | 1996-09-17 | 1998-03-26 | The Regents Of The University Of California | Benzothiadiazide derivatives and their use as allosteric up-modulators of the ampa receptor |
CA2335510A1 (en) * | 1998-06-25 | 1999-12-29 | Merck & Co., Inc. | Naphtho[1,8-de]thiasin-2-yl methyl carbapenem antibacterials |
DE10004572A1 (en) * | 2000-02-02 | 2001-08-09 | Boehringer Ingelheim Pharma | New positive allosteric AMPA receptor modulators (PAARM), processes for their production and their use as medicines |
-
2001
- 2001-05-17 DE DE10123952A patent/DE10123952A1/en not_active Withdrawn
-
2002
- 2002-05-15 CA CA002449189A patent/CA2449189A1/en not_active Abandoned
- 2002-05-15 YU YU90403A patent/YU90403A/en unknown
- 2002-05-15 PL PL02364053A patent/PL364053A1/en not_active Application Discontinuation
- 2002-05-15 WO PCT/EP2002/005338 patent/WO2002100411A1/en not_active Application Discontinuation
- 2002-05-15 CN CNA028100832A patent/CN1533278A/en active Pending
- 2002-05-15 SK SK1422-2003A patent/SK14222003A3/en unknown
- 2002-05-15 EA EA200301167A patent/EA006608B1/en not_active IP Right Cessation
- 2002-05-15 EE EEP200300566A patent/EE200300566A/en unknown
- 2002-05-15 UY UY27290A patent/UY27290A1/en not_active Application Discontinuation
- 2002-05-15 JP JP2003503232A patent/JP2004529980A/en not_active Abandoned
- 2002-05-15 BR BR0209796-6A patent/BR0209796A/en not_active Expired - Fee Related
- 2002-05-15 CZ CZ20033112A patent/CZ20033112A3/en unknown
- 2002-05-15 EP EP02750931A patent/EP1404340A1/en not_active Withdrawn
- 2002-05-15 HU HU0401273A patent/HUP0401273A3/en unknown
- 2002-05-15 IL IL15864202A patent/IL158642A0/en unknown
- 2002-05-15 MX MXPA03010373A patent/MXPA03010373A/en unknown
- 2002-05-15 NZ NZ530154A patent/NZ530154A/en unknown
- 2002-05-15 KR KR10-2003-7014965A patent/KR20040007572A/en not_active Application Discontinuation
- 2002-05-17 AR ARP020101827A patent/AR036332A1/en not_active Suspension/Interruption
-
2003
- 2003-10-30 ZA ZA200308466A patent/ZA200308466B/en unknown
- 2003-11-07 BG BG108324A patent/BG108324A/en active Pending
- 2003-11-14 HR HR20030933A patent/HRP20030933A2/en not_active Application Discontinuation
- 2003-11-14 NO NO20035088A patent/NO20035088D0/en not_active Application Discontinuation
- 2003-11-17 EC EC2003004852A patent/ECSP034852A/en unknown
- 2003-12-01 CO CO03105591A patent/CO5550460A2/en unknown
Also Published As
Publication number | Publication date |
---|---|
NO20035088L (en) | 2003-11-14 |
IL158642A0 (en) | 2004-05-12 |
DE10123952A1 (en) | 2002-11-21 |
WO2002100411A1 (en) | 2002-12-19 |
BR0209796A (en) | 2004-06-01 |
SK14222003A3 (en) | 2004-05-04 |
CA2449189A1 (en) | 2002-12-19 |
ZA200308466B (en) | 2004-05-24 |
EE200300566A (en) | 2004-02-16 |
NZ530154A (en) | 2005-09-30 |
CZ20033112A3 (en) | 2004-03-17 |
EP1404340A1 (en) | 2004-04-07 |
ECSP034852A (en) | 2003-12-24 |
CO5550460A2 (en) | 2005-08-31 |
KR20040007572A (en) | 2004-01-24 |
BG108324A (en) | 2004-12-30 |
HUP0401273A2 (en) | 2004-10-28 |
EA200301167A1 (en) | 2004-06-24 |
MXPA03010373A (en) | 2004-03-16 |
NO20035088D0 (en) | 2003-11-14 |
UY27290A1 (en) | 2002-12-31 |
AR036332A1 (en) | 2004-09-01 |
JP2004529980A (en) | 2004-09-30 |
CN1533278A (en) | 2004-09-29 |
HRP20030933A2 (en) | 2004-04-30 |
HUP0401273A3 (en) | 2006-11-28 |
EA006608B1 (en) | 2006-02-24 |
PL364053A1 (en) | 2004-12-13 |
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