YU62991A - Karbapenemska jedinjenja - Google Patents
Karbapenemska jedinjenjaInfo
- Publication number
- YU62991A YU62991A YU62991A YU62991A YU62991A YU 62991 A YU62991 A YU 62991A YU 62991 A YU62991 A YU 62991A YU 62991 A YU62991 A YU 62991A YU 62991 A YU62991 A YU 62991A
- Authority
- YU
- Yugoslavia
- Prior art keywords
- group
- piperazinyl
- pyrrolidinyl
- substituted
- group derived
- Prior art date
Links
- 150000001875 compounds Chemical class 0.000 title abstract 3
- 125000004193 piperazinyl group Chemical group 0.000 abstract 8
- 125000000719 pyrrolidinyl group Chemical group 0.000 abstract 4
- 125000000217 alkyl group Chemical group 0.000 abstract 3
- 239000001257 hydrogen Substances 0.000 abstract 3
- 229910052739 hydrogen Inorganic materials 0.000 abstract 3
- KXDHJXZQYSOELW-UHFFFAOYSA-N Carbamic acid Chemical group NC(O)=O KXDHJXZQYSOELW-UHFFFAOYSA-N 0.000 abstract 2
- 125000003545 alkoxy group Chemical group 0.000 abstract 2
- 125000003277 amino group Chemical group 0.000 abstract 2
- 125000004185 ester group Chemical group 0.000 abstract 2
- 150000002431 hydrogen Chemical class 0.000 abstract 2
- 229910052757 nitrogen Inorganic materials 0.000 abstract 2
- 125000004433 nitrogen atom Chemical group N* 0.000 abstract 2
- 125000001453 quaternary ammonium group Chemical group 0.000 abstract 2
- 150000007970 thio esters Chemical group 0.000 abstract 2
- UFHFLCQGNIYNRP-UHFFFAOYSA-N Hydrogen Chemical compound [H][H] UFHFLCQGNIYNRP-UHFFFAOYSA-N 0.000 abstract 1
- 125000004414 alkyl thio group Chemical group 0.000 abstract 1
- 230000000844 anti-bacterial effect Effects 0.000 abstract 1
- 125000006244 carboxylic acid protecting group Chemical group 0.000 abstract 1
- 150000002148 esters Chemical class 0.000 abstract 1
- 150000004677 hydrates Chemical class 0.000 abstract 1
- 125000002768 hydroxyalkyl group Chemical group 0.000 abstract 1
- ZLTPDFXIESTBQG-UHFFFAOYSA-N isothiazole Chemical compound C=1C=NSC=1 ZLTPDFXIESTBQG-UHFFFAOYSA-N 0.000 abstract 1
- 150000002545 isoxazoles Chemical class 0.000 abstract 1
- -1 isoxazoloquinolonyl Chemical group 0.000 abstract 1
- 150000003839 salts Chemical class 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D477/00—Heterocyclic compounds containing 1-azabicyclo [3.2.0] heptane ring systems, i.e. compounds containing a ring system of the formula:, e.g. carbapenicillins, thienamycins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulphur-containing hetero ring
- C07D477/10—Heterocyclic compounds containing 1-azabicyclo [3.2.0] heptane ring systems, i.e. compounds containing a ring system of the formula:, e.g. carbapenicillins, thienamycins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulphur-containing hetero ring with hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached in position 4, and with a carbon atom having three bonds to hetero atoms with at the most one bond to halogen, e.g. an ester or nitrile radical, directly attached in position 2
- C07D477/12—Heterocyclic compounds containing 1-azabicyclo [3.2.0] heptane ring systems, i.e. compounds containing a ring system of the formula:, e.g. carbapenicillins, thienamycins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulphur-containing hetero ring with hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached in position 4, and with a carbon atom having three bonds to hetero atoms with at the most one bond to halogen, e.g. an ester or nitrile radical, directly attached in position 2 with hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, attached in position 6
- C07D477/14—Heterocyclic compounds containing 1-azabicyclo [3.2.0] heptane ring systems, i.e. compounds containing a ring system of the formula:, e.g. carbapenicillins, thienamycins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulphur-containing hetero ring with hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached in position 4, and with a carbon atom having three bonds to hetero atoms with at the most one bond to halogen, e.g. an ester or nitrile radical, directly attached in position 2 with hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, attached in position 6 with hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, attached in position 3
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D477/00—Heterocyclic compounds containing 1-azabicyclo [3.2.0] heptane ring systems, i.e. compounds containing a ring system of the formula:, e.g. carbapenicillins, thienamycins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulphur-containing hetero ring
- C07D477/26—Heterocyclic compounds containing 1-azabicyclo [3.2.0] heptane ring systems, i.e. compounds containing a ring system of the formula:, e.g. carbapenicillins, thienamycins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulphur-containing hetero ring with hetero atoms or carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. an ester or nitrile radical, directly attached in position 4
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
- Y02P20/00—Technologies relating to chemical industry
- Y02P20/50—Improvements relating to the production of bulk chemicals
- Y02P20/55—Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Communicable Diseases (AREA)
- Pharmacology & Pharmacy (AREA)
- Oncology (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US50613590A | 1990-04-09 | 1990-04-09 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| YU62991A true YU62991A (sh) | 1994-04-05 |
Family
ID=24013339
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| YU62991A YU62991A (sh) | 1990-04-09 | 1991-04-08 | Karbapenemska jedinjenja |
Country Status (17)
| Country | Link |
|---|---|
| EP (1) | EP0451764A1 (index.php) |
| JP (1) | JPH04234884A (index.php) |
| AU (1) | AU7420591A (index.php) |
| BR (1) | BR9101418A (index.php) |
| CA (1) | CA2039987A1 (index.php) |
| CS (1) | CS94391A2 (index.php) |
| FI (1) | FI911666A7 (index.php) |
| HU (1) | HUT57769A (index.php) |
| IE (1) | IE911161A1 (index.php) |
| IL (1) | IL97797A0 (index.php) |
| MC (1) | MC2262A1 (index.php) |
| MX (1) | MX25231A (index.php) |
| NO (1) | NO911357L (index.php) |
| PT (1) | PT97287A (index.php) |
| TW (1) | TW216420B (index.php) |
| YU (1) | YU62991A (index.php) |
| ZA (1) | ZA912279B (index.php) |
Families Citing this family (17)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CA2001203C (en) * | 1988-10-24 | 2001-02-13 | Thomas P. Demuth, Jr. | Novel antimicrobial dithiocarbamoyl quinolones |
| EP0997466A1 (en) * | 1988-10-24 | 2000-05-03 | PROCTER & GAMBLE PHARMACEUTICALS, INC. | Novel antimicrobial lactam-quinolones |
| US5273973A (en) * | 1988-10-24 | 1993-12-28 | Norwich Eaton Pharmaceuticals, Inc. | Antimicrobial quinolonyl esters |
| US5491139A (en) * | 1988-10-24 | 1996-02-13 | The Procter & Gamble Company | Antimicrobial quinolonyl lactams |
| US5328908A (en) * | 1988-10-24 | 1994-07-12 | Procter & Gamble Pharmaceuticals, Inc. | Antimicrobial quinolone thioureas |
| US5180719A (en) * | 1988-10-24 | 1993-01-19 | Norwich Eaton Pharmaceuticals, Inc. | Antimicrobial quinolonyl lactam esters |
| SG47533A1 (en) * | 1990-04-18 | 1998-04-17 | Procter & Gamble Pharma | Antimicrobial quinolonyl lactams |
| EP0606336B1 (en) * | 1991-10-01 | 1997-03-19 | PROCTER & GAMBLE PHARMACEUTICALS, INC. | Process for making antimicrobial quinolonyl lactams |
| DE4234078A1 (de) * | 1992-10-09 | 1994-04-14 | Bayer Ag | Chinoloncarbonsäuren |
| DE4234330A1 (de) * | 1992-10-12 | 1994-04-14 | Bayer Ag | Chinoloncarbonsäuren |
| ATE190972T1 (de) * | 1994-08-02 | 2000-04-15 | Procter & Gamble | Verfahren zur herstellung von antimikrobiellen verbindungen |
| MX9700872A (es) * | 1994-08-02 | 1997-05-31 | Procter & Gamble | Procedimiento para producir antimicrobianos de quinolonil-lactama y compuestos intermediarios novedosos. |
| US5607928A (en) * | 1994-08-05 | 1997-03-04 | Zeneca Limited | Carbapenem derivatives containing a bicyclic ketone substituent and their use as anti-infectives |
| EP0695753A1 (en) * | 1994-08-05 | 1996-02-07 | Zeneca Limited | Carbapenem derivatives containing a bicyclic substituent, process for their preparation, and their use |
| ATE247086T1 (de) * | 1997-01-21 | 2003-08-15 | Merck & Co Inc | Verfahren zur herstellung von zwischenprodukten des carbapenems |
| US5973142A (en) * | 1997-01-21 | 1999-10-26 | Yasuda; Nobuyoshi | Process for synthesizing carbapenem intermediates |
| US6080854A (en) * | 1997-08-25 | 2000-06-27 | Merck & Co., Inc. | Process for synthesizing carbapenem intermediates |
Family Cites Families (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CA1179675A (en) * | 1981-01-30 | 1984-12-18 | Erwin Gotschi | 7-oxo-1-azabicyclo ¬3,2,0| heptene-2-derivatives |
| US4680292A (en) * | 1984-12-13 | 1987-07-14 | Merck & Co., Inc. | Carbapenems and 1-methylcarbapenems having a 2-heteroaryliumaliphatic substituent |
| US4767762A (en) * | 1985-12-23 | 1988-08-30 | Abbott Laboratories | Tricyclic quinoline and naphthyride antibacterials |
| EP0366193A3 (en) * | 1988-10-24 | 1992-01-08 | Norwich Eaton Pharmaceuticals, Inc. | Novel antimicrobial quinolonyl lactams |
| EP0997466A1 (en) * | 1988-10-24 | 2000-05-03 | PROCTER & GAMBLE PHARMACEUTICALS, INC. | Novel antimicrobial lactam-quinolones |
| ES2148135T3 (es) * | 1988-10-24 | 2000-10-16 | Norwich Eaton Pharma | Nuevos esteres antimicrobianos de quinolonil lactamas. |
-
1991
- 1991-03-26 ZA ZA912279A patent/ZA912279B/xx unknown
- 1991-04-05 MX MX2523191A patent/MX25231A/es unknown
- 1991-04-05 CS CS91943A patent/CS94391A2/cs unknown
- 1991-04-05 JP JP3099750A patent/JPH04234884A/ja active Pending
- 1991-04-05 MC MC932182A patent/MC2262A1/fr unknown
- 1991-04-08 AU AU74205/91A patent/AU7420591A/en not_active Abandoned
- 1991-04-08 NO NO91911357A patent/NO911357L/no unknown
- 1991-04-08 CA CA002039987A patent/CA2039987A1/en not_active Abandoned
- 1991-04-08 TW TW080102600A patent/TW216420B/zh active
- 1991-04-08 YU YU62991A patent/YU62991A/sh unknown
- 1991-04-08 FI FI911666A patent/FI911666A7/fi not_active Application Discontinuation
- 1991-04-08 HU HU911132A patent/HUT57769A/hu unknown
- 1991-04-08 EP EP91105550A patent/EP0451764A1/en not_active Withdrawn
- 1991-04-08 PT PT97287A patent/PT97287A/pt not_active Application Discontinuation
- 1991-04-08 IE IE116191A patent/IE911161A1/en unknown
- 1991-04-08 IL IL97797A patent/IL97797A0/xx unknown
- 1991-04-09 BR BR919101418A patent/BR9101418A/pt unknown
Also Published As
| Publication number | Publication date |
|---|---|
| MX25231A (es) | 1993-10-01 |
| CA2039987A1 (en) | 1991-10-10 |
| TW216420B (index.php) | 1993-11-21 |
| HU911132D0 (en) | 1991-10-28 |
| AU7420591A (en) | 1991-10-10 |
| PT97287A (pt) | 1992-01-31 |
| BR9101418A (pt) | 1991-11-26 |
| FI911666A7 (fi) | 1991-10-10 |
| ZA912279B (en) | 1992-02-26 |
| HUT57769A (en) | 1991-12-30 |
| JPH04234884A (ja) | 1992-08-24 |
| IE911161A1 (en) | 1991-10-09 |
| IL97797A0 (en) | 1992-06-21 |
| NO911357D0 (no) | 1991-04-08 |
| NO911357L (no) | 1991-10-10 |
| EP0451764A1 (en) | 1991-10-16 |
| MC2262A1 (fr) | 1993-04-26 |
| FI911666A0 (fi) | 1991-04-08 |
| CS94391A2 (en) | 1991-11-12 |
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