YU59899A - Medicinski aerosolni proizvodi - Google Patents

Medicinski aerosolni proizvodi

Info

Publication number
YU59899A
YU59899A YU59899A YU59899A YU59899A YU 59899 A YU59899 A YU 59899A YU 59899 A YU59899 A YU 59899A YU 59899 A YU59899 A YU 59899A YU 59899 A YU59899 A YU 59899A
Authority
YU
Yugoslavia
Prior art keywords
ciclesonide
aerosol products
medicinal aerosol
hfc
solubilize
Prior art date
Application number
YU59899A
Other languages
English (en)
Inventor
Martin J. Oliver
Kanu M. Fatania
John S. Scott
Helgert Muller
Original Assignee
Byk Gulden Lomberg Chemische Fabrik Gmbh.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from GBGB9710496.2A external-priority patent/GB9710496D0/en
Priority claimed from GBGB9803990.2A external-priority patent/GB9803990D0/en
Application filed by Byk Gulden Lomberg Chemische Fabrik Gmbh. filed Critical Byk Gulden Lomberg Chemische Fabrik Gmbh.
Publication of YU59899A publication Critical patent/YU59899A/sh
Publication of RS49628B publication Critical patent/RS49628B/sr

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/10—Dispersions; Emulsions
    • A61K9/12—Aerosols; Foams
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/007—Pulmonary tract; Aromatherapy
    • A61K9/0073—Sprays or powders for inhalation; Aerolised or nebulised preparations generated by other means than thermal energy
    • A61K9/008—Sprays or powders for inhalation; Aerolised or nebulised preparations generated by other means than thermal energy comprising drug dissolved or suspended in liquid propellant for inhalation via a pressurized metered dose inhaler [MDI]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
    • A61K31/58—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids containing heterocyclic rings, e.g. danazol, stanozolol, pancuronium or digitogenin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/10—Dispersions; Emulsions
    • A61K9/12—Aerosols; Foams
    • A61K9/124—Aerosols; Foams characterised by the propellant
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A61P11/06—Antiasthmatics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Epidemiology (AREA)
  • Dispersion Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pulmonology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Otolaryngology (AREA)
  • Pain & Pain Management (AREA)
  • Rheumatology (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Containers And Packaging Bodies Having A Special Means To Remove Contents (AREA)
  • Materials For Medical Uses (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
  • Thermotherapy And Cooling Therapy Devices (AREA)

Abstract

Farmaceutska aerosolska formulacija, pogodna za oralnu i/ili nazalnu inhalaciju, koja sadrži antiinflamatorni lek ciklezonid, fluorougljovodonične propelente kao što su HFC 134a i/ili 227, i etanol u količini dovoljnoj da se rastvori ciklezonid (i, u datom slučaju, različite sastojke, kao što su površinski aktivne supstance). Formulacije ispoljavaju veoma poželjnu fizičku i hemijsku stabilnost, kao i odlične karakteristike u doziranju.[A pharmaceutical aerosol formulation suitable for oral and/or nasal inhalation including the anti-inflammatory drug ciclesonide, hydrofluorocarbon propellants such as HFC 134a and/or 227, and ethanol in an amount sufficient to solubilize the ciclesonide (and various optional ingredients, such as surfactant). The formulations exhibit very desirable physical and chemical stability, as well as excellent delivery characteristics.
YUP-598/99A 1997-05-21 1998-05-18 Medicinski aerosolni proizvodi RS49628B (sr)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GBGB9710496.2A GB9710496D0 (en) 1997-05-21 1997-05-21 Medicinal aerosol products
GBGB9803990.2A GB9803990D0 (en) 1998-02-25 1998-02-25 Medicinal aerosol products

Publications (2)

Publication Number Publication Date
YU59899A true YU59899A (sh) 2002-06-19
RS49628B RS49628B (sr) 2007-08-03

Family

ID=26311564

Country Status (28)

Country Link
US (1) US6120752A (sh)
EP (1) EP0983058B1 (sh)
JP (4) JP2001526685A (sh)
KR (1) KR100527643B1 (sh)
CN (1) CN1149073C (sh)
AT (1) ATE245966T1 (sh)
AU (1) AU726835B2 (sh)
BG (1) BG64268B1 (sh)
BR (1) BR9809448A (sh)
CA (1) CA2290521C (sh)
CZ (1) CZ298253B6 (sh)
DE (1) DE69816811T2 (sh)
DK (1) DK0983058T3 (sh)
EA (1) EA002381B1 (sh)
ES (1) ES2205491T3 (sh)
HK (1) HK1027027A1 (sh)
HU (1) HU226694B1 (sh)
IL (1) IL132738A (sh)
ME (1) ME01631B (sh)
NO (2) NO327716B1 (sh)
NZ (1) NZ500874A (sh)
PL (1) PL191523B1 (sh)
PT (1) PT983058E (sh)
RS (1) RS49628B (sh)
SK (1) SK283930B6 (sh)
TR (1) TR199902863T2 (sh)
UA (1) UA58551C2 (sh)
WO (1) WO1998052542A1 (sh)

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AR026073A1 (es) 1999-10-20 2002-12-26 Nycomed Gmbh Composicion farmaceutica acuosa que contiene ciclesonida
AR026072A1 (es) * 1999-10-20 2002-12-26 Nycomed Gmbh Composicion farmaceutica que contiene ciclesonida para aplicacion a la mucosa
GB0002798D0 (en) * 2000-02-09 2000-03-29 Glaxo Group Ltd Actuator nozzle for metered dose inhaler
GB0208742D0 (en) 2002-04-17 2002-05-29 Bradford Particle Design Ltd Particulate materials
GB0207899D0 (en) * 2002-04-05 2002-05-15 3M Innovative Properties Co Formoterol and cielesonide aerosol formulations
WO2004033478A2 (en) * 2002-10-08 2004-04-22 Sepracor Inc. Fatty acid modified forms of glucocorticoids and their use as anti-inflammatory
PT1563032E (pt) * 2002-10-25 2012-05-28 Honeywell Int Inc Composições contendo olefinas substituídas com flúor
WO2004052374A1 (en) * 2002-12-12 2004-06-24 Altana Pharma Ag Combination medicament
MY143936A (en) * 2003-03-27 2011-07-29 Nycomed Gmbh Process for preparing crystalline ciclesonide with defined particle size
US20060293293A1 (en) * 2003-05-22 2006-12-28 Altana Pharma Ag Salmeterol and ciclesonide combination
AU2004246819A1 (en) 2003-06-13 2004-12-23 Nycomed Gmbh Formoterol and ciclesonide combination
WO2005025578A1 (en) * 2003-09-16 2005-03-24 Altana Pharma Ag Use of ciclesonide for the treatment of respiratory diseases
GB2406283B (en) 2003-09-24 2006-04-05 Altana Pharma Ag Compliance monitor and method
US9308199B2 (en) 2004-04-29 2016-04-12 Honeywell International Inc. Medicament formulations
AR041873A1 (es) * 2003-10-30 2005-06-01 Pablo Cassara Srl Lab Una formulacion farmaceutica en aerosol adecuada para la inhalacion oral o nasal que contienen glucocorticoides en solucion estable al almacenamiento; un metodo para estabilzar formulaciones y uso de un agente estabilizante
PE20050941A1 (es) 2003-12-16 2005-11-08 Nycomed Gmbh Suspensiones acuosas de ciclesonida para nebulizacion
WO2005065185A2 (en) * 2003-12-24 2005-07-21 Collegium Pharmaceuticals, Inc. Temperature-stable formulations, and methods of development thereof
WO2005102354A1 (en) * 2004-04-20 2005-11-03 Altana Pharma Ag Use of ciclesonide for the treatment of respiratory diseases in a smoking patient
CA2579007A1 (en) * 2004-09-10 2006-03-16 Altana Pharma Ag Ciclesonide and syk inhibitor combination and methods of use thereof
CN101175479A (zh) * 2005-03-16 2008-05-07 霍尼韦尔国际公司 药物递送制剂、装置和方法
WO2007068007A1 (en) * 2005-12-07 2007-06-14 Harm Benjamin Steyn Use of a disinfectant for treating respiratory tract infections
ES2538082T3 (es) 2007-02-11 2015-06-17 Map Pharmaceuticals Inc Método de administración terapéutica de DHE para permitir el rápido alivio de migraña mientras que se minimiza el perfil de efectos secundarios
US20100120737A1 (en) * 2008-11-10 2010-05-13 Martin Feth Amorphous ciclesonide
AU2010221972B2 (en) * 2009-03-09 2012-07-05 Mikasa Seiyaku Co., Ltd. Steroid compound
WO2011135585A2 (en) 2010-04-28 2011-11-03 Cadila Healthcare Limited Aqueous pharmaceutical solution of ciclesonide
EP2627325A1 (en) * 2010-10-12 2013-08-21 Cipla Limited Pharmaceutical composition
MX2014001940A (es) 2011-08-18 2014-03-27 Takeda Gmbh Producto farmaceutico de aerosol para administracion por inhalacion oral o nasal.
CN102335132A (zh) * 2011-10-12 2012-02-01 中山大学 一种细辛脑吸入气雾剂及其制备方法
US9603907B2 (en) 2012-02-01 2017-03-28 Protalix Ltd. Dry powder formulations of dNase I
WO2016057693A1 (en) 2014-10-10 2016-04-14 Alnylam Pharmaceuticals, Inc. Methods and compositions for inhalation delivery of conjugated oligonucleotide

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GB2077229B (en) * 1980-05-16 1983-08-03 Neotechnic Eng Ltd Valve assembly for a pressurized aerosoldispensing container
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Also Published As

Publication number Publication date
NO995667D0 (no) 1999-11-18
PT983058E (pt) 2003-12-31
KR20010012810A (ko) 2001-02-26
EP0983058B1 (en) 2003-07-30
PL336885A1 (en) 2000-07-17
NO327716B1 (no) 2009-09-14
IL132738A0 (en) 2001-03-19
DE69816811T2 (de) 2004-04-15
JP2016169222A (ja) 2016-09-23
NO995667L (no) 1999-11-18
RS49628B (sr) 2007-08-03
WO1998052542A1 (en) 1998-11-26
JP2011102301A (ja) 2011-05-26
AU726835B2 (en) 2000-11-23
CA2290521C (en) 2006-10-10
IL132738A (en) 2004-06-20
PL191523B1 (pl) 2006-06-30
ES2205491T3 (es) 2004-05-01
BG103902A (en) 2000-05-31
CN1149073C (zh) 2004-05-12
US6120752A (en) 2000-09-19
EA002381B1 (ru) 2002-04-25
JP6178459B2 (ja) 2017-08-09
KR100527643B1 (ko) 2005-11-15
HUP0002691A2 (hu) 2001-02-28
CZ412499A3 (cs) 2000-02-16
HK1027027A1 (en) 2001-01-05
UA58551C2 (uk) 2003-08-15
DK0983058T3 (da) 2003-11-24
SK283930B6 (sk) 2004-05-04
NO2009024I1 (no) 2009-10-26
CZ298253B6 (cs) 2007-08-08
DE69816811D1 (de) 2003-09-04
NZ500874A (en) 2001-09-28
ATE245966T1 (de) 2003-08-15
JP2015024999A (ja) 2015-02-05
CA2290521A1 (en) 1998-11-26
BR9809448A (pt) 2000-06-20
JP2001526685A (ja) 2001-12-18
EA199900991A1 (ru) 2000-08-28
AU7496298A (en) 1998-12-11
EP0983058A1 (en) 2000-03-08
BG64268B1 (bg) 2004-08-31
CN1257421A (zh) 2000-06-21
ME01631B (me) 2007-08-03
JP6087882B2 (ja) 2017-03-01
HUP0002691A3 (en) 2001-04-28
NO2009024I2 (no) 2010-08-16
HU226694B1 (en) 2009-06-29
SK157699A3 (en) 2000-05-16
TR199902863T2 (xx) 2000-05-22

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