YU46044B - Postopek za pripravo substituiranih 9-(1- ali 3-monoaciloksi ali 13-diaciloksi-2-propoksimetil)purinov - Google Patents

Postopek za pripravo substituiranih 9-(1- ali 3-monoaciloksi ali 13-diaciloksi-2-propoksimetil)purinov

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Publication number
YU46044B
YU46044B YU37387A YU37387A YU46044B YU 46044 B YU46044 B YU 46044B YU 37387 A YU37387 A YU 37387A YU 37387 A YU37387 A YU 37387A YU 46044 B YU46044 B YU 46044B
Authority
YU
Yugoslavia
Prior art keywords
formula
compound
acid addition
carbon atoms
alkali metal
Prior art date
Application number
YU37387A
Other languages
English (en)
Other versions
YU37387A (en
Inventor
J.P.H. Verheyden
J.C. Martin
Original Assignee
Syntex (U.S.A.) Inc.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from YU19083A external-priority patent/YU19083A/xx
Application filed by Syntex (U.S.A.) Inc. filed Critical Syntex (U.S.A.) Inc.
Priority to YU37387A priority Critical patent/YU46044B/sh
Publication of YU37387A publication Critical patent/YU37387A/xx
Publication of YU46044B publication Critical patent/YU46044B/sh

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Abstract

POSTOPEK ZA PRIPRAVO SUBSTITUIRANIH 9-(1- ALI 3-MONOACILOKSI ALI 13-DIACILOKSI-2-PROPOKSIMETIL)PURINOV, kot antivirusnih sredstev s formulo in njihovih kislinskih adicijskih soli, prednostno farmacevtsko sprejemljivih kislinskih adicijskih soli, kjer je R1 vodik ali -C(O)R7, kjer je R7 vodik, alkil z 1 do 19 atomi ogljika, alkoksialkil z 2 do 9 atomi ogljika, alkenil z 2 do 19 atomi ogljika, fenil, 1-adamantil, 2-karboksietil ali karboksimetil in njihove farmacevtsko sprejemljive soli alkalijskih kovin, R2 je -C(O)R7, kjer je R7 definiran kot zgoraj, označen s tem, da presnovimo spojino s formulo kjer je "Y" acetilna zaščitna skupina, z alkoholno raztopino baze, da nastanejo spojine s formulo (Ia), kjer sta R1 in R2-C(O)R7, in po potrebi pretvorimo spojino s formulo (Ia) v njeno kislinsko adicijsko sol ali pretvorimo spojino s formulo (Ia) v njeno sol alkalijske kovine ali pretvorimo kislinsko adicijsko sol v ustrezno spojino s formulo (Ia) ali pretvorimo sol alkalijske kovine v ustrezno spojino s formulo (Ia).
YU37387A 1983-01-27 1987-03-06 Postopek za pripravo substituiranih 9-(1- ali 3-monoaciloksi ali 13-diaciloksi-2-propoksimetil)purinov YU46044B (sh)

Priority Applications (1)

Application Number Priority Date Filing Date Title
YU37387A YU46044B (sh) 1983-01-27 1987-03-06 Postopek za pripravo substituiranih 9-(1- ali 3-monoaciloksi ali 13-diaciloksi-2-propoksimetil)purinov

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
YU19083A YU19083A (en) 1983-01-27 1983-01-27 Process for preparation of substituted 9-(1- or 3-monoacyloxy or 1,3 diacyloxy-2-propoxymethyl) purines as antivirus agents
YU37387A YU46044B (sh) 1983-01-27 1987-03-06 Postopek za pripravo substituiranih 9-(1- ali 3-monoaciloksi ali 13-diaciloksi-2-propoksimetil)purinov

Publications (2)

Publication Number Publication Date
YU37387A YU37387A (en) 1987-08-31
YU46044B true YU46044B (sh) 1992-12-21

Family

ID=25549626

Family Applications (1)

Application Number Title Priority Date Filing Date
YU37387A YU46044B (sh) 1983-01-27 1987-03-06 Postopek za pripravo substituiranih 9-(1- ali 3-monoaciloksi ali 13-diaciloksi-2-propoksimetil)purinov

Country Status (1)

Country Link
YU (1) YU46044B (sh)

Also Published As

Publication number Publication date
YU37387A (en) 1987-08-31

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