YU28978A - Process for producing antiinflammatory imidazoles and corresponding sulfoxides and sulfones thereof - Google Patents

Process for producing antiinflammatory imidazoles and corresponding sulfoxides and sulfones thereof

Info

Publication number
YU28978A
YU28978A YU00289/78A YU28978A YU28978A YU 28978 A YU28978 A YU 28978A YU 00289/78 A YU00289/78 A YU 00289/78A YU 28978 A YU28978 A YU 28978A YU 28978 A YU28978 A YU 28978A
Authority
YU
Yugoslavia
Prior art keywords
sulfones
imidazoles
corresponding sulfoxides
antiinflammatory
producing
Prior art date
Application number
YU00289/78A
Other languages
English (en)
Inventor
C S Cherofsky
R T Sharpe
Original Assignee
Du Pont
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Du Pont filed Critical Du Pont
Publication of YU28978A publication Critical patent/YU28978A/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D233/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings
    • C07D233/54—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members
    • C07D233/66—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D233/84—Sulfur atoms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pain & Pain Management (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Rheumatology (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
YU00289/78A 1977-02-09 1978-02-08 Process for producing antiinflammatory imidazoles and corresponding sulfoxides and sulfones thereof YU28978A (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US76721977A 1977-02-09 1977-02-09
US05/865,831 US4182769A (en) 1977-02-09 1978-01-05 Anti-inflammatory 1-substituted-4,5-diaryl-2-(substituted-thio) imidazoles and their corresponding sulfoxides and sulfones

Publications (1)

Publication Number Publication Date
YU28978A true YU28978A (en) 1983-01-21

Family

ID=27117878

Family Applications (1)

Application Number Title Priority Date Filing Date
YU00289/78A YU28978A (en) 1977-02-09 1978-02-08 Process for producing antiinflammatory imidazoles and corresponding sulfoxides and sulfones thereof

Country Status (27)

Country Link
US (1) US4182769A (fi)
JP (1) JPS53130665A (fi)
AR (1) AR221590A1 (fi)
AT (1) AT363076B (fi)
AU (1) AU524360B2 (fi)
CA (1) CA1107286A (fi)
CH (1) CH643834A5 (fi)
DE (1) DE2805166A1 (fi)
DK (1) DK16878A (fi)
ES (1) ES466793A1 (fi)
FI (1) FI68619C (fi)
FR (1) FR2380264A1 (fi)
GB (1) GB1587373A (fi)
GR (1) GR64157B (fi)
HU (1) HU181868B (fi)
IE (1) IE46454B1 (fi)
IL (1) IL53996A (fi)
IT (1) IT1092439B (fi)
LU (1) LU79028A1 (fi)
MX (1) MX5934E (fi)
NL (1) NL7801454A (fi)
NO (1) NO149813C (fi)
NZ (1) NZ186411A (fi)
PT (1) PT67625B (fi)
SE (1) SE7801466L (fi)
SU (1) SU867301A3 (fi)
YU (1) YU28978A (fi)

Families Citing this family (25)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE2823197A1 (de) * 1978-05-24 1979-11-29 Schering Ag Neue imidazolderivate, verfahren zu ihrer herstellung und diese enthaltende pharmazeutische praeparate
US4308277A (en) * 1978-08-10 1981-12-29 Ciba-Geigy Corporation 2,4,5-Trisubstituted imidazolines and pharmaceutical compositions containing same
CY1344A (en) * 1978-08-10 1987-01-16 Ciba Geigy Ag Substituted anthranilic acid amides,process for their preparation,and pharmaceutical compositions containing them
US4199592A (en) * 1978-08-29 1980-04-22 E. I. Du Pont De Nemours And Company Antiinflammatory 4,5-diaryl-2-nitroimidazoles
DK337779A (da) * 1978-10-02 1980-04-03 Du Pont Fremgangsmaade til fremstilling af antiinflammatoriske 2-substituerede 1h-phenantro (9,10)-imidazoler
DE2856909A1 (de) * 1978-12-28 1980-07-17 Schering Ag Neue imidazolderivate, verfahren zu ihrer herstellung und diese enthaltende pharmazeutische praeparate
IT1110282B (it) * 1979-02-19 1985-12-23 Acraf Tio-indazoli basici
DE3025484A1 (de) * 1980-07-03 1982-02-04 Schering Ag, 1000 Berlin Und 4619 Bergkamen Neue imidazol-derivate, verfahren zu ihrer herstellung und diese enthaltende pharmazeutische praeparate
US4438117A (en) 1980-09-03 1984-03-20 E. I. Du Pont De Nemours And Company 2-Substituted thio-4,5-diarylpyrimidines
US4355041A (en) * 1982-01-04 1982-10-19 E. I. Du Pont De Nemours And Company 4,5-Bis-(4-fluorophenyl)-1-(4-nitrobenzyl)-2-[((1,1,2,2-tetrafluoroethyl)sulfonyl]-1H-imidazole, composition and use
US4503065A (en) * 1982-08-03 1985-03-05 E. I. Du Pont De Nemours And Company Antiinflammatory 4,5-diaryl 1-2-halo imidazoles
ZA826501B (en) * 1982-09-06 1984-04-25 Du Pont Anti-hypertensive imidazole derivative
DE3504678A1 (de) * 1985-02-12 1986-08-14 A. Nattermann & Cie GmbH, 5000 Köln Neue imidazolyl-oxyalkansaeuren und -thioalkansaeuren, ihre derivate und verfahren zu ihrer herstellung
DE3508665A1 (de) * 1985-03-12 1986-09-18 Hoechst Ag, 6230 Frankfurt Heterocyclische sulfide und ihre anwendung als immunmodulatoren
US4686231A (en) * 1985-12-12 1987-08-11 Smithkline Beckman Corporation Inhibition of 5-lipoxygenase products
US4780470A (en) * 1986-08-19 1988-10-25 Smithkline Beckman Corporation Inhibition of interleukin-1 by monocytes and/or macrophages
US5300519A (en) * 1988-07-06 1994-04-05 The University Of Sheffield Immunosuppressive agents
US5098707A (en) * 1989-07-31 1992-03-24 Merck & Co., Inc. Imidazole compounds and their use as transglutaminase inhibitors
US5030644A (en) * 1989-07-31 1991-07-09 Merck & Co., Inc. Imidazole compounds and their use as transglutaminase inhibitors
JPH03145473A (ja) * 1989-10-27 1991-06-20 Hisamitsu Pharmaceut Co Inc 新規なイミダゾール酢酸誘導体
GB9005966D0 (en) * 1990-03-16 1990-05-09 May & Baker Ltd New compositions of matter
DE4010797A1 (de) * 1990-04-04 1991-10-10 Hoechst Ag Substituierte azole, verfahren zu deren herstellung, diese enthaltende mittel und deren verwendung
KR20010014288A (ko) * 1997-06-30 2001-02-26 오르토-맥네일 파마슈티칼, 인코퍼레이티드 염증성 질환의 치료에 유용한 2-치환된 이미다졸
FR2823747B1 (fr) * 2001-04-24 2003-05-23 Oreal Nouveaux composes de la famille des 3-alkyl-(4,5 diphenyl- imidazol-1-yl) et leur utilisation comme anti-inflammatoires
JP6648108B2 (ja) 2014-07-18 2020-02-14 オハイオ ユニバーシティー 生物学的シグナル伝達を改変するためのイミダゾール及びチアゾール組成物

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
SE345453B (fi) * 1965-10-21 1972-05-29 Ciba Geigy Ag
US3707475A (en) * 1970-11-16 1972-12-26 Pfizer Antiinflammatory imidazoles
US3929807A (en) * 1971-05-10 1975-12-30 Ciba Geigy Corp 2-Substituted-4(5)-(aryl)-5(4)-(2,3 or -4-pyridyl)-imidazoles
JPS5343958B2 (fi) * 1972-07-29 1978-11-24

Also Published As

Publication number Publication date
FI780429A (fi) 1978-08-10
US4182769A (en) 1980-01-08
FR2380264A1 (fr) 1978-09-08
HU181868B (en) 1983-11-28
PT67625A (en) 1978-03-01
JPS53130665A (en) 1978-11-14
GB1587373A (en) 1981-04-01
DK16878A (da) 1978-08-10
MX5934E (es) 1984-08-30
PT67625B (en) 1979-07-17
DE2805166A1 (de) 1978-08-10
NO780432L (no) 1978-08-10
NO149813B (no) 1984-03-19
IT1092439B (it) 1985-07-12
NO149813C (no) 1984-06-27
IL53996A (en) 1982-04-30
FI68619B (fi) 1985-06-28
AU524360B2 (en) 1982-09-16
CA1107286A (en) 1981-08-18
IE46454B1 (en) 1983-06-15
AR221590A1 (es) 1981-02-27
IL53996A0 (en) 1978-04-30
LU79028A1 (fr) 1979-05-25
CH643834A5 (de) 1984-06-29
FI68619C (fi) 1985-10-10
AU3309778A (en) 1979-08-16
SU867301A3 (ru) 1981-09-23
AT363076B (de) 1981-07-10
ES466793A1 (es) 1979-08-01
IT7820079A0 (it) 1978-02-07
NZ186411A (en) 1981-03-16
GR64157B (en) 1980-02-05
SE7801466L (sv) 1978-08-10
NL7801454A (nl) 1978-08-11
IE780280L (en) 1978-08-09
ATA87078A (de) 1980-12-15

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