Classifications

• • A—HUMAN NECESSITIES
  • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
  • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
  • A61K8/00—Cosmetics or similar toiletry preparations
  • A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
  • A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
  • A61K8/31—Hydrocarbons
• • A—HUMAN NECESSITIES
  • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
  • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
  • A61K8/00—Cosmetics or similar toiletry preparations
  • A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
  • A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
  • A61K8/33—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing oxygen
  • A61K8/37—Esters of carboxylic acids
• • A—HUMAN NECESSITIES
  • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
  • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
  • A61K8/00—Cosmetics or similar toiletry preparations
  • A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
  • A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
  • A61K8/33—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing oxygen
  • A61K8/39—Derivatives containing from 2 to 10 oxyalkylene groups
• • A—HUMAN NECESSITIES
  • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
  • A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
  • A61Q1/00—Make-up preparations; Body powders; Preparations for removing make-up
  • A61Q1/14—Preparations for removing make-up
• • A—HUMAN NECESSITIES
  • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
  • A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
  • A61Q19/00—Preparations for care of the skin
  • A61Q19/10—Washing or bathing preparations

Definitions

• the present invention relates to a cleansing agent, in particular a cleansing agent that is highly effective at removing keratin plugs that form in pores.
• Makeup cosmetics used in makeup are required to be water-resistant and durable, and products with improved properties have been developed.
• makeup cosmetics are often not sufficiently cleaned with regular water after use, so cleansing agents such as cleansing oils are often used.
• the present invention provides a cleansing agent that is highly effective in cleaning cosmetics and keratin plugs, and also has excellent removability and usability after cleaning.
• a cleansing agent comprising: (B) an oil; and (C) an ester of a polyol having a trihydric or higher alcohol skeleton and a carboxylic acid.
• the component (A) is represented by the following formula (1): (Wherein, AO is propyleneoxy or butyleneoxy; n is a number from 1 to 20.
• [4] The cleansing agent according to any one of [1] to [3], wherein the content of the component (A) based on the total mass of the cleansing agent is 0.5 to 30 mass%.
• [5] The cleansing agent according to any one of [1] to [4], wherein the component (B) forms an oil phase, and the oil phase is a continuous phase.
• [6] The cleansing agent according to any one of [1] to [5], wherein the content of the component (B) based on the total mass of the cleansing agent is 10 to 95 mass%.
• the present invention provides a cleansing agent that has high cleansing power and can easily clean keratin plugs that were previously difficult to clean, can be easily washed off the skin after cleaning, and has an excellent feel when used.
• the cleansing agent comprises: (A) an ester of an alkylene glycol or a polyalkylene glycol with pivalic acid,
• the composition essentially comprises (B) an oil, and (C) an ester of a polyol having a trihydric or higher alcohol skeleton and a carboxylic acid.
• the cleansing agent according to the present invention contains an ester of an alkylene glycol or polyalkylene glycol and pivalic acid (hereinafter, sometimes referred to as component (A)).
• component (A) provides excellent cleansing ability against dirt on the skin, particularly against keratin plugs.
• Component (A) is an alkylene glycol or polyalkylene glycol to which pivalic acid is ester-bonded to a terminal hydroxyl group.
• Pivalic acid may be bonded to only one of the two terminal hydroxyl groups of the alkylene glycol or polyalkylene glycol, but it is preferable that pivalic acid is bonded to both hydroxyl groups.
• alkylene group constituting the alkylene glycol or polyalkylene glycol is not particularly limited, but examples include ethyleneoxy, propyleneoxy, butyleneoxy, etc., and may include combinations of these. Of these, alkylene glycols or polyalkylene glycols that contain propyleneoxy or butyleneoxy as a constituent unit are preferred.
• component (A) examples include those represented by the following formula (1).
• AO is propyleneoxy or butyleneoxy; n is a number from 1 to 20.
• AO is preferably propyleneoxy.
• n is preferably 1 to 10, and more preferably 2 to 5.
• component (A) is PPG-3 dipivalate.
• the content of component (A) is not particularly limited, but the content of component (A) based on the total mass of the cleanser is preferably 0.5 to 30 mass%, and more preferably 1 to 15 mass%. By setting the content of component (A) within this range, it is possible to achieve excellent cleaning effects.
• component (A) may be considered an oil depending on the type of AO and the number of n, but in this invention, anything that falls under component (A) is excluded from the oil (component (B)) described below.
• the cleansing agent according to the present invention contains an oil (hereinafter, sometimes referred to as component (B)).
• the oil used in the present invention is not particularly limited as long as it is compatible with cosmetics applied to the skin and dirt adhering to the skin, and is harmless to the human body.
• Component (B) can be broadly divided into polar oils and non-polar oils, either of which can be used in the present invention.
• polar oils examples include ester oils, higher fatty acids, and higher aliphatic alcohols.
• Ester oils include, for example, octyl octanoate, nonyl nonanoate, cetyl octanoate, isopropyl myristate, octyldodecyl myristate, isopropyl palmitate, ethylhexyl palmitate, butyl stearate, hexyl laurate, myristyl myristate, decyl oleate, hexyldecyl dimethyloctanoate, cetyl lactate, myristyl lactate, lanolin acetate, isocetyl stearate, isocetyl isostearate, cholesteryl 12-hydroxystearate, ethylene glycol di-2-ethylhexanoate, N-alkyl glycol monoisostearate, neopentyl glycol dicaprate, diisostearyl malate, cetyl 2-ethylhe
• higher fatty acids examples include lauric acid, myristic acid, palmitic acid, stearic acid, behenic acid, oleic acid, undecylenic acid, tallic acid, isostearic acid, linoleic acid, linoleic acid, eicosapentaenoic acid (EPA), and docosahexaenoic acid (DHA).
• higher alcohols examples include straight-chain alcohols (e.g., lauryl alcohol, cetyl alcohol, stearyl alcohol, behenyl alcohol, myristyl alcohol, oleyl alcohol, cetostearyl alcohol, etc.), branched-chain alcohols (e.g., lanolin alcohol, cholesterol, phytosterol, hexyldodecanol, isostearyl alcohol, octyldodecanol, etc.), etc.
• straight-chain alcohols e.g., lauryl alcohol, cetyl alcohol, stearyl alcohol, behenyl alcohol, myristyl alcohol, oleyl alcohol, cetostearyl alcohol, etc.
• branched-chain alcohols e.g., lanolin alcohol, cholesterol, phytosterol, hexyldodecanol, isostearyl alcohol, octyldodecanol, etc.
• non-polar oils examples include hydrocarbon oils and silicone oils.
• Hydrocarbon oils include paraffin, squalane, squalene, isohexadecane, isododecane, hydrogenated polydecene, hydrogenated isopolybutene, petrolatum, etc.
• silicone oils examples include chain silicone oils such as dimethicone, methylphenylpolysiloxane, caprylyl methicone, diphenylsiloxyphenyltrimethicone, methylhydrogenpolysiloxane, and trimethylsiloxysilicate, and cyclic silicone oils such as octamethylcyclotetrasiloxane, decamethylcyclopentasiloxane, and dodecamethylcyclohexasiloxane.
• chain silicone oils such as dimethicone, methylphenylpolysiloxane, caprylyl methicone, diphenylsiloxyphenyltrimethicone, methylhydrogenpolysiloxane, and trimethylsiloxysilicate
• cyclic silicone oils such as octamethylcyclotetrasiloxane, decamethylcyclopentasiloxane, and dodecamethylcyclohexasiloxane.
• the content of component (B) is preferably 10 to 95% by mass based on the total mass of the cleanser.
• the content of component (B) is generally high, and is more preferably 50 to 95% by mass based on the total mass of the cleanser.
• the content of component (B) is preferably 1 to 30% by mass based on the total mass of the cleanser.
• the cleanser according to the present invention can exhibit high cleaning power by containing component (B) at such a content.
• having a bicontinuous phase refers to a state in which both water and oil form continuous phases in the cleanser composition.
• the component (B) used in the present invention may be either a polar oil or a non-polar oil, or a mixture of these may be used. Ester oil is preferred as the polar oil, and hydrocarbon oil is preferred as the non-polar oil.
• the cleansing agent according to the present invention contains an ester of a polyol having a trihydric or higher alcohol skeleton and a carboxylic acid (hereinafter, sometimes referred to as component (C)).
• component (C) an ester of a polyol having a trihydric or higher alcohol skeleton and a carboxylic acid
• polyols having a trivalent or higher alcohol skeleton include, for example, glycerin, sorbitol, and erythritol. It is preferable that this polyol does not contain a nitrogen-containing substituent such as an amino group, or a sulfur-containing substituent such as a sulfo group.
• the carboxylic acid preferably has 8 or more carbon atoms, and more preferably 10 or more carbon atoms.
• the use of a carboxylic acid with a relatively large number of carbon atoms increases lipophilicity and improves compatibility with component (B).
• component (C) may include those that are considered to be oils if they contain a long-chain alkyl group in the structure, but in the present invention, those that fall under component (C) are excluded from the oil (component (B)).
• esters of polyols and carboxylic acids include monoesters, diesters, triesters, and tetraesters, with triesters and tetraesters being preferred. Esters containing unreacted hydroxyl groups may also be used.
• polyols having an alcohol skeleton of three or more valences may contain a polyalkyleneoxy structure. That is,
• component (C) examples include polyglyceryl-10 dioleate, PEG-20 glyceryl triisostearate, polyoxyethylene sorbitol tetraisostearate, polyglyceryl-10 pentastearate, polyglyceryl-6 dicaprate, PEG-8 glyceryl isostearate, and PEG-7 glyceryl coconut oil fatty acid.
• Such component (C) has both hydrophilic and hydrophobic parts, and therefore also functions as a surfactant.
• the HLB of component (C) is not particularly limited, but is preferably 14 or less, and more preferably 10 to 13.
• the HLB is determined by the Griffin method.
• the content of component (C) is not particularly limited, but the content of component (C) based on the total mass of the cleanser is preferably 5 to 35 mass%, and more preferably 5 to 20 mass%. Furthermore, when the cleanser according to the present invention has a bicontinuous phase, the content of component (C) based on the total mass of the cleanser is preferably 20 to 35 mass%.
• the cleansing agent according to the present invention may contain water (hereinafter, may be referred to as component (D)).
• water water used in cosmetics, quasi-drugs, etc. may be used, for example, purified water, ion-exchanged water, tap water, etc.
• the cleansing agent according to the present invention is an oily composition containing a high content of oil, but may also contain a small amount of water.
• the content of the (D) component is preferably 0 to 50% by mass relative to the total mass of the cleanser according to the present invention.
• the content of the (D) component is generally low in order to increase the oil content.
• the content of the (D) component is preferably 0 to 4% by mass relative to the total mass of the cleanser.
• the water content can be increased to make the cleanser according to the present invention a water-in-oil composition.
• compositions can be prepared by applying various emulsification techniques, and the water content can be increased to 90% by mass or more, but in the cleanser according to the present invention, by making the water content 0 to 50% by mass relative to the total mass of the cleanser, both excellent cleansing properties and a good usability can be achieved.
• the content of the (D) component is preferably 20 to 50% by mass relative to the total mass of the cleanser.
• the cleansing agent of the present invention may contain other optional components depending on the purpose, so long as the effects of the present invention are not impaired.
• optional components include components that are generally incorporated into cleansing agents, such as stabilizers, for example, thickeners, preservatives, antioxidants, chelating agents, pH adjusters, surfactants other than component (C), drugs (for example, vitamin C, vitamin E, amino acids, herbal medicines, anti-inflammatory agents, bactericides, etc.), lubricants, ultraviolet absorbing agents, colorants, fragrances, or protein derivatives.
• the cleansing agent of the present invention is used for cleaning, but is particularly suitable for use as a cleansing oil for cleaning cosmetics and other products applied to the skin.
• Examples 1 to 5 and Comparative Examples 1 to 3 The compositions of each example were prepared according to the formulation shown in Table 1. These compositions were evaluated for keratinocyte dissolving ability, removability after washing, and usability according to the following criteria. The results are also shown in Table 1.
• Example 5 shows a case where the composition has a bicontinuous phase.
• Keratolytic (1) An artificial keratin plug consisting of the following components was prepared. Palmitic acid 3.6% Stearic acid 18.9% Oleic acid 11.7% Phytosteryl/octyldodecyl lauroyl glutamate 19.8% ⁇ Squalene 27.1% ⁇ Macadamia nut oil 14.4% Phytosterol 4.5% (2) The prepared artificial keratin plug was dyed red and applied onto a white smear using a doctor blade. (3) 30 g of each composition was placed in a 50 ml screw tube, and the coated supple cut into a size of 2 cm x 2 cm was placed in the composition.

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Citations (8)

• 2024
  • 2024-06-06 JP JP2025527872A patent/JPWO2024262323A1/ja active Pending
  • 2024-06-06 WO PCT/JP2024/020640 patent/WO2024262323A1/ja not_active Ceased
  • 2024-06-06 CN CN202480033590.XA patent/CN121218968A/zh active Pending

Patent Citations (8)

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