WO2024180845A1 - 貫通孔を有する樹脂成形品とその成形方法、成形型、及び樹脂成形品を用いた無針注射器 - Google Patents

貫通孔を有する樹脂成形品とその成形方法、成形型、及び樹脂成形品を用いた無針注射器 Download PDF

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Publication number
WO2024180845A1
WO2024180845A1 PCT/JP2023/043896 JP2023043896W WO2024180845A1 WO 2024180845 A1 WO2024180845 A1 WO 2024180845A1 JP 2023043896 W JP2023043896 W JP 2023043896W WO 2024180845 A1 WO2024180845 A1 WO 2024180845A1
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WIPO (PCT)
Prior art keywords
molded product
resin molded
core pin
hole
recess
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Ceased
Application number
PCT/JP2023/043896
Other languages
English (en)
French (fr)
Japanese (ja)
Inventor
貞之 福井
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Daicel Corp
Original Assignee
Daicel Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Daicel Corp filed Critical Daicel Corp
Priority to JP2025503589A priority Critical patent/JPWO2024180845A1/ja
Priority to CN202380094153.4A priority patent/CN120641258A/zh
Priority to EP23925397.4A priority patent/EP4674590A1/en
Publication of WO2024180845A1 publication Critical patent/WO2024180845A1/ja
Anticipated expiration legal-status Critical
Ceased legal-status Critical Current

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Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
    • A61M5/178—Syringes
    • A61M5/30—Syringes for injection by jet action, without needle, e.g. for use with replaceable ampoules or carpules
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B29—WORKING OF PLASTICS; WORKING OF SUBSTANCES IN A PLASTIC STATE IN GENERAL
    • B29C—SHAPING OR JOINING OF PLASTICS; SHAPING OF MATERIAL IN A PLASTIC STATE, NOT OTHERWISE PROVIDED FOR; AFTER-TREATMENT OF THE SHAPED PRODUCTS, e.g. REPAIRING
    • B29C33/00—Moulds or cores; Details thereof or accessories therefor
    • B29C33/0033—Moulds or cores; Details thereof or accessories therefor constructed for making articles provided with holes
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B29—WORKING OF PLASTICS; WORKING OF SUBSTANCES IN A PLASTIC STATE IN GENERAL
    • B29C—SHAPING OR JOINING OF PLASTICS; SHAPING OF MATERIAL IN A PLASTIC STATE, NOT OTHERWISE PROVIDED FOR; AFTER-TREATMENT OF THE SHAPED PRODUCTS, e.g. REPAIRING
    • B29C33/00—Moulds or cores; Details thereof or accessories therefor
    • B29C33/30—Mounting, exchanging or centering
    • B29C33/303—Mounting, exchanging or centering centering mould parts or halves, e.g. during mounting
    • B29C33/304—Mounting, exchanging or centering centering mould parts or halves, e.g. during mounting centering cores
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B29—WORKING OF PLASTICS; WORKING OF SUBSTANCES IN A PLASTIC STATE IN GENERAL
    • B29C—SHAPING OR JOINING OF PLASTICS; SHAPING OF MATERIAL IN A PLASTIC STATE, NOT OTHERWISE PROVIDED FOR; AFTER-TREATMENT OF THE SHAPED PRODUCTS, e.g. REPAIRING
    • B29C33/00—Moulds or cores; Details thereof or accessories therefor
    • B29C33/42—Moulds or cores; Details thereof or accessories therefor characterised by the shape of the moulding surface, e.g. ribs or grooves
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B29—WORKING OF PLASTICS; WORKING OF SUBSTANCES IN A PLASTIC STATE IN GENERAL
    • B29C—SHAPING OR JOINING OF PLASTICS; SHAPING OF MATERIAL IN A PLASTIC STATE, NOT OTHERWISE PROVIDED FOR; AFTER-TREATMENT OF THE SHAPED PRODUCTS, e.g. REPAIRING
    • B29C45/00—Injection moulding, i.e. forcing the required volume of moulding material through a nozzle into a closed mould; Apparatus therefor
    • B29C45/17—Component parts, details or accessories; Auxiliary operations
    • B29C45/26—Moulds
    • B29C45/2628—Moulds with mould parts forming holes in or through the moulded article, e.g. for bearing cages
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61J—CONTAINERS SPECIALLY ADAPTED FOR MEDICAL OR PHARMACEUTICAL PURPOSES; DEVICES OR METHODS SPECIALLY ADAPTED FOR BRINGING PHARMACEUTICAL PRODUCTS INTO PARTICULAR PHYSICAL OR ADMINISTERING FORMS; DEVICES FOR ADMINISTERING FOOD OR MEDICINES ORALLY; BABY COMFORTERS; DEVICES FOR RECEIVING SPITTLE
    • A61J1/00—Containers specially adapted for medical or pharmaceutical purposes
    • A61J1/14—Details; Accessories therefor
    • A61J1/1468—Containers characterised by specific material properties
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
    • A61M5/178—Syringes
    • A61M5/30—Syringes for injection by jet action, without needle, e.g. for use with replaceable ampoules or carpules
    • A61M5/3007—Syringes for injection by jet action, without needle, e.g. for use with replaceable ampoules or carpules with specially designed jet passages at the injector's distal end
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B29—WORKING OF PLASTICS; WORKING OF SUBSTANCES IN A PLASTIC STATE IN GENERAL
    • B29C—SHAPING OR JOINING OF PLASTICS; SHAPING OF MATERIAL IN A PLASTIC STATE, NOT OTHERWISE PROVIDED FOR; AFTER-TREATMENT OF THE SHAPED PRODUCTS, e.g. REPAIRING
    • B29C45/00—Injection moulding, i.e. forcing the required volume of moulding material through a nozzle into a closed mould; Apparatus therefor
    • B29C45/17—Component parts, details or accessories; Auxiliary operations
    • B29C45/26—Moulds
    • B29C45/2616—Moulds having annular mould cavities
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B29—WORKING OF PLASTICS; WORKING OF SUBSTANCES IN A PLASTIC STATE IN GENERAL
    • B29L—INDEXING SCHEME ASSOCIATED WITH SUBCLASS B29C, RELATING TO PARTICULAR ARTICLES
    • B29L2031/00—Other particular articles
    • B29L2031/753—Medical equipment; Accessories therefor
    • B29L2031/7544—Injection needles, syringes

Definitions

  • the present invention relates to a resin molded product having a through hole, a molding method thereof, a molding die, and a needleless syringe using the resin molded product.
  • Patent Document 1 a method has been proposed for molding resin molded products with through holes, in which a core pin with a through hole shape is inserted into molten resin present in a cavity to form the product.
  • tiny burrs are generated at the opening of the through hole during the process of inserting a core pin into the molten resin to form a hole, and there is a risk that the tiny burrs will peel off when the molded product is used.
  • the technology disclosed herein has been developed in consideration of the above-mentioned circumstances, and its purpose is to prevent minute burrs from forming at the openings of through holes in resin molded products that have through holes.
  • a resin molded product as one aspect of the technology disclosed herein is a resin molded product formed by injection molding, in which a through hole is opened at a predetermined end face of the resin molded product, and a protrusion protruding from the predetermined end face in the axial direction of the through hole is formed along the opening edge of the through hole.
  • the thickness of the protrusion in a direction perpendicular to the axial direction may be configured to be 1 ⁇ m or more and 1000 ⁇ m or less.
  • the thickness of the protrusion in a direction perpendicular to the axial direction may be configured to be 3 ⁇ m or more and 100 ⁇ m or less.
  • the thickness of the protrusion in a direction perpendicular to the axial direction may be configured to be 5 ⁇ m or more and 15 ⁇ m or less.
  • the above-mentioned resin molded product may be formed as a container for containing the injection target substance in a needleless syringe that injects the injection target substance into a target area without using an injection needle, and the through hole may define a flow path for the injection target substance, and the injection target substance may be injected into the target area using an opening on the specified end face side of the through hole as an injection outlet.
  • the technology disclosed herein is a molding method for molding a resin molded product by injection molding, the method comprising: a mold closing step of closing a molding die; and an injection step of injecting resin into the molding die, the molding die comprising a cavity in which a space into which the resin is injected is formed; and a core which is inserted into the space by moving relative to the cavity along a predetermined first direction and defines an area in the space into which the resin does not flow, the core having a core pin which extends in the first direction of the molding die and defines the shape of the through hole in the space, the cavity having an end face defining surface which faces the space and defines the shape of the predetermined end face of the resin molded product, the end face defining surface having an opening in the space,
  • the method may include forming a core pin receiving hole including a recess having an inner wall recessed in the first direction and a receiving portion that opens into the recess and extends in the first direction to receive the tip of the core pin of the core inserted into the space, the
  • the distance between the core pin and the inner wall surface of the recess at the opening of the recess may be configured to be 10 ⁇ m or more and 100 ⁇ m or less when the core pin is inserted into the core pin receiving hole.
  • the distance between the core pin and the inner wall surface of the recess at the opening of the recess may be configured to be 5 ⁇ m or more and 15 ⁇ m or less when the core pin is inserted into the core pin receiving hole.
  • the distance between the core pin and the inner wall surface of the receiving section at the opening of the receiving section may be configured to be 10 ⁇ m or less when the core pin is inserted into the core pin receiving hole.
  • the distance between the core pin and the inner wall surface of the receiving section at the opening of the receiving section may be configured to be 5 ⁇ m or less when the core pin is inserted into the core pin receiving hole.
  • the distance between the core pin and the inner wall surface of the receiving section at the opening of the receiving section may be configured to be 2.5 ⁇ m or less when the core pin is inserted into the core pin receiving hole.
  • the depth of the recess from the end face defining surface in the axial direction may be 20 ⁇ m or more.
  • the depth of the recess from the end face defining surface in the axial direction may be 50 ⁇ m or more.
  • the depth of the recess from the end face defining surface in the axial direction may be 100 ⁇ m or more.
  • the shape of the opening of the through hole and the shape of the recess in a cross section perpendicular to the first direction may be similar to each other, and in the mold closing step, when the core pin is inserted into the core pin receiving hole, the inner wall of the recess may face along the side of the core pin.
  • the opening of the recess may be elliptical in a cross section perpendicular to the first direction.
  • the recess may be formed in a columnar shape extending in the first direction toward the direction in which the core pin is inserted into the core pin receiving hole.
  • the technology disclosed herein is also a molding die for injection molding a resin molded product having a through hole that opens to a predetermined end face, the molding die comprising: a cavity in which a space into which resin is injected is formed; and a core that is inserted into the space by moving relative to the cavity along a predetermined first direction and defines an area in the space into which the resin does not flow, the core having a core pin that extends in the first direction and defines the shape of the through hole in the space, and the cavity having an end face defining surface that faces the space and defines the shape of the predetermined end face of the resin molded product.
  • the end face defining surface may be formed with a core pin receiving hole including a recess that opens into the space and is recessed in the first direction, and a receiving portion that opens into the recess and extends in the first direction to receive the tip of the core pin of the core inserted into the space, the opening width of the recess is set to be larger than the opening width of the receiving portion, and the recess receives the resin so that the resin injected into the space does not reach the receiving portion, so that a protrusion protruding from the predetermined end face of the resin molded product is formed along the opening edge of the through hole.
  • the technology disclosed herein may also be a needleless syringe that includes the aforementioned resin molded product formed as a container for holding an injection target substance, and that injects the injection target substance into a target area without using an injection needle.
  • This disclosure makes it possible to provide a resin molded product that is less likely to develop minute burrs at the opening of the through hole.
  • FIG. 1 is a schematic cross-sectional view of a resin molded product according to an embodiment.
  • FIG. 2 is a schematic cross-sectional view of a molding die and a resin molded product according to the embodiment.
  • FIG. 3 is a partially enlarged view of FIG.
  • FIG. 4 is a partially enlarged view of FIG.
  • FIG. 5 is a flowchart of a molding method for a resin molded product according to an embodiment.
  • FIG. 6 is a schematic cross-sectional view of a needle-free syringe using a resin molded product according to an embodiment.
  • FIG. 1 is a schematic cross-sectional view of a resin molded product 1 according to an embodiment.
  • FIG. 2 is a cross-sectional view taken along the central axis C of a mold according to an embodiment.
  • FIG. 2 shows an example of the resin molded product 1 shown in FIG. 1 being molded by a mold 10 used during injection molding.
  • the direction in which the core 11 is inserted relatively to the cavity 12 in a mold closing process described later corresponds to the "predetermined first direction”.
  • the "first direction” is a direction parallel to the central axis C of the mold 10 and the central axis C' of the through hole of the resin molded product 1.
  • the mold 10 can mold the resin molded product 1 by undergoing an injection process in which molten resin is injected into the internal space 121 after the mold closing process.
  • the direction in which the internal space 121 is opened to receive the core 11 is referred to as the base end side
  • the direction in which the core pin receiving hole 124 is arranged is referred to as the tip end side.
  • Such base end side and tip end side merely indicate the relative positional relationship between the resin molded product 1 and each element of the molding die 10.
  • FIG. 1 is a schematic cross-sectional view of a resin molded product 1 according to an embodiment.
  • the resin molded product 1 is a molded product obtained by molding a molten resin using a molding die 10 described later.
  • the resin molded product 1 is formed as a container for accommodating an injection target substance used in a needleless syringe.
  • the central axis of the through hole 4 of the resin molded product 1 is conveniently referred to as the central axis C'.
  • the resin molded product 1 is formed in a substantially cylindrical shape extending in a first direction.
  • the resin molded product 1 has an accommodation space 2 for accommodating an arbitrary substance, a predetermined end face 3 which is a part that defines the shape of the resin molded product 1, a through hole 4 that opens into the predetermined end face 3, and a side portion 5 which is a part that defines the shape of the resin molded product 1.
  • the accommodation space 2 is formed as a hollow portion of the resin molded product 1.
  • the predetermined end face 3 constitutes the tip face of the resin molded product 1
  • the side portion 5 constitutes the side face of the resin molded product 1.
  • the through hole 4 is a through hole that communicates the storage space 2 with the external space of the resin molded product 1, and opens to the predetermined end face 3.
  • the through hole 4 is formed so as to extend along the central axis C' of the through hole 4 toward the predetermined end face 3, which is the tip side of the storage space 2, and an opening 4A is formed on the tip side of the through hole 4.
  • the through hole 4 defines a flow path of the injection target substance described below in the needleless syringe 100 described below, and further, the opening 4A of the through hole 4 is formed in a circular shape and is used as an injection port for the injection target substance.
  • a protrusion 3A is formed around the opening 4A, protruding from the specified end face 3 in the direction of the central axis C'.
  • the protrusion 3A is formed in a ring shape along the opening edge of the opening 4A, but for example, the opening 4A may be circular, while the protrusion 3A may be formed in an elliptical or polygonal shape.
  • the cross-sectional shape of the opening 4A (cross-sectional shape inside the opening) and the cross-sectional shape of the protrusion 3A (cross-sectional shape of the radially outer outer edge of the protrusion formed on the opening edge) may be different in a direction perpendicular to the central axis C'.
  • the protrusion 3A may not be ring-shaped, but may have a shape such as a Landolt ring with a part cut out from the ring, or a shape formed intermittently.
  • the shape of the opening 4A may be polygonal, etc., and in that case, it is preferable that the protrusion 3A is formed along the opening edge of the opening 4A.
  • the thickness of the protrusion 3A in the direction perpendicular to the central axis C' is configured to be 1 ⁇ m or more and 1000 ⁇ m or less, preferably 3 ⁇ m or more and 100 ⁇ m or less, and more preferably 5 ⁇ m or more and 15 ⁇ m or less.
  • [Molding mold] 2 is a cross-sectional view taken along a central axis C of a molding die 10 according to an embodiment.
  • the molding die 10 is configured to extend along a first direction.
  • the molding die 10 includes a cavity 12 having an internal space 121 for accommodating a molten resin, and a core 11 defining an area into which the molten resin does not flow in the internal space 121.
  • the core 11 is inserted and moves relative to the cavity 12 along the first direction in a mold closing process to occupy a part of the internal space 121, whereby the area into which the molten resin does not flow in an injection process is formed as an accommodating space 2 for the resin molded product 1.
  • FIGS. 3 and 4 are partial enlarged views of FIG. 2.
  • the core 11 has a core body 111 and a core pin 112, and extends in a first direction.
  • the core body 111 occupies a part of the internal space 121 of the cavity 12 to form the storage space 2 for the resin molded product 1.
  • the core pin 112 has a conical shape that converges toward the tip, extends toward the tip side of the core body 111, and defines the shape of the through hole 4 of the resin molded product 1.
  • the shape of the core pin 112 is not limited, and may be, for example, a polygonal prism shape or an elliptical cylinder shape.
  • the cavity 12 has an internal space 121 that contains molten resin, a side surface defining surface 122 and an end surface defining surface 123 that define the internal space 121, and a core pin receiving hole 124 for receiving the core pin 112.
  • the side surface defining surface 122 defines the shape of the side surface portion 5 of the resin molded product 1
  • the end surface defining surface 123 defines the shape of the specified end surface 3. Therefore, the portion from the end surface defining surface 123 to the tip side may be formed of a different material to make it easier to open the mold, making it easier to remove the resin molded product 1 molded by the molding die 10.
  • the core pin receiving hole 124 extends from the end surface defining surface 123 to the tip side in the first direction and opens into the internal space 121.
  • the core pin receiving hole 124 has a cylindrical recess 124A and a receiving portion 124B.
  • the shapes of the core pin receiving hole 124 and the core pin 112 are not limited.
  • the core pin receiving hole 124 may be a polygonal columnar shape having a similar cross-sectional shape in a cross section perpendicular to the first direction, or when the shape of the core pin 112 is an elliptical cylinder, the core pin receiving hole 124 may be an elliptical cylinder shape having a similar cross-sectional shape in a cross section perpendicular to the first direction.
  • the shape of the recess 124A is not limited to a cylindrical shape, and may be another columnar shape. In either case, it is preferable that the protrusion 3A of the resin molded product 1 is formed so as to follow the shape of the opening 4A.
  • the core pin receiving hole 124 has a stepped structure, and has a recess 124A that opens into the internal space 121 and is recessed in the first direction to form an inner wall surface 124AS, and a receiving portion 124B that opens into the recess 124A, extends in the first direction, and is formed by an inner wall surface 124BS.
  • the side surface 112S of the core pin faces along the inner wall surface 124AS and is shaped to form a circular hole in the resin molded product 1.
  • the opening width W1 which is the opening diameter of the recess 124A
  • the opening width W2 which is the opening diameter of the receiving portion 124B, so that when the molten resin is injected into the internal space 121 in the injection process described below, the molten resin is prevented from flowing into the receiving portion 124B located on the tip side of the recess 124A.
  • the receiving portion 124B is shaped to receive the tip of the core pin 112, and when the core 11 is inserted into the cavity 12 in a mold closing step described later, the tip of the core pin 112 reaches further toward the tip side than the recess 124A.
  • the protrusion 3A is formed by the molten resin remaining in the recess 124A, and the core pin 112 is positioned so as to penetrate the remaining molten resin, so that the shape of the through hole 4 in the resin molded product 1 is determined by the core pin 112.
  • the shape of the opening 4A of the through hole 4 of the resin molded product 1 formed by the core pin 112 and the shape of the cross section perpendicular to the first direction in the recess 124A are configured to be similar to each other, and when the core 11 is inserted into the cavity 12, the inner wall surface 124AS of the recess 124A is configured to face along the side surface 112S of the core pin 112, thereby preventing the molten resin from flowing into the receiving portion 124B located further towards the tip side than the recess 124A.
  • the opening width W1 of the recess 124A is larger than the opening width W2 of the receiving portion 124B.
  • the receiving portion 124B functions as a guide for the core pin 112, and the core pin 112 and the recess 124A do not wear out, and the core pin 112 and the receiving portion 124B wear out first.
  • the gap between the inner wall surface 124AS of the recess 124A and the side surface 112S of the core pin 112 is made large to retain the molten resin, so that even if the core pin 112 or the core pin receiving hole 124 wears out due to continuous use, etc., it is possible to prevent the generation of minute burrs near the opening 4A of the resin molded product 1 to be molded.
  • the receiving portion 124B functions as a guide for the core pin 112, so that the opening width W1 of the recess 124A and the opening width W2 of the receiving portion 124B are formed with the same opening width, and compared to when the core pin receiving hole 124 does not have a stepped structure, it is possible to reduce the collision between the core pin 112 and the end face defining surface 123, or the breakage of the core pin 112 due to deformation caused by the expansion of the molding die 10 due to the heat of the molten resin.
  • the opening width of the recess 124A is formed larger than the opening width of the receiving portion 124B, there is a margin for adjustment when inserting the core pin 112 into the core pin receiving hole 124, which is also useful as an aid for insertion.
  • the core pin 112 can be more reliably inserted into the core pin receiving hole 124, making it easier to form the through hole 4.
  • the distance t1 between the side surface 112S of the core pin 112 and the inner wall surface 124AS of the recess 124A is configured to be 10 ⁇ m or more and 100 ⁇ m or less at the opening of the recess 124A, which is on the same plane as the end face defining surface 123, and more preferably 5 ⁇ m or more and 15 ⁇ m or less.
  • the core pin receiving hole 124 is configured so that when the core pin 112 is inserted, the distance t2 between the side surface 112S of the core pin 112 and the inner wall surface 124BS of the receiving portion 124B is 10 ⁇ m or less, preferably 5 ⁇ m or less, and more preferably 2.5 ⁇ m or less. This reliably prevents the inflow of molten resin into the receiving portion 124B, and prevents the formation of minute burrs near the opening 4A of the resin molded product 1.
  • the recess 124A of the core pin receiving hole 124 is configured so that the depth t3 from the end face defining surface 123 to the tip side is 20 ⁇ m or more, preferably 50 ⁇ m or more, and more preferably 100 ⁇ m or more. This intentionally keeps the molten resin in the recess 124A and prevents the molten resin from reaching the receiving portion 124B, thereby preventing the generation of minute burrs.
  • the shape of the opening of the recess 124A of the core pin receiving hole 124 may be an ellipse or the like in a cross section perpendicular to the first direction.
  • the inner wall surface 124AS of the recess 124A may be formed in a cone shape that converges toward the tip side, which is the closed end side of the core pin receiving hole 124, or a dome-shaped funnel shape that bulges toward the side defining surface 122. In this way, as long as the configuration can give a strong shape of a certain height to the protrusion 3A of the resin molded product 1, it may be modified depending on the application.
  • the recess 124A is formed in a columnar shape, the cross section along the first direction is rectangular, and such a configuration makes it easier to manufacture the mold.
  • the recess 124A is formed in a cone shape that converges toward the tip side, it helps to guide the core pin 112 when it is inserted into the receiving portion 124B.
  • Fig. 5 is a flowchart of the method for molding the resin molded product 1 according to the embodiment. The following description will be given based on Fig. 5.
  • molten resin that will be the material for the resin molded product 1 is prepared.
  • raw materials such as resin pellets are kept in a molten state to prepare for the subsequent process.
  • the core 11 is moved relative to the cavity 12 so as to be inserted therein, and is positioned so that when the molding die 10 is closed, the core 11 occupies a portion of the internal space 121 of the cavity 12, thereby defining an area into which molten resin will not flow in a later process. In this way, the area is formed as the storage space 2 and the through hole 4.
  • step S13 a nozzle (not shown) is pressed against any molten resin inlet (not shown) of the mold and the molten resin is poured in, so that the molten resin takes the shape of the resin molded product 1.
  • step S14 in which the molten resin is cooled, the resin is set in the shape of the resin molded product 1.
  • the object that was a fluid molten resin is fixed into the shape of the resin molded product 1, including the through holes 4 and the protrusions 3A.
  • step S15 the core 11 is moved relative to the cavity 12 so as to be extracted, and the mold is opened. This results in the resin molded product 1.
  • Fig. 6 is a schematic cross-sectional view of a needle-free syringe 100 using a resin molded article 1 according to an embodiment.
  • the resin molded article 1 is formed as a container for containing an injection target substance used in the needle-free syringe 100
  • Fig. 6 shows a cross-sectional view of the resin molded article 1 attached to the needle-free syringe 100.
  • the specific substance contained in the injection target substance examples include, for example, a biologically derived substance that can be injected into a target area that is a living body, and a substance that exhibits the desired physiological activity.
  • biologically derived substances include DNA, RNA, nucleic acids, antibodies, cells, etc.
  • biologically active substances include medicines made of low molecular weight molecules, proteins, peptides, etc., vaccines, inorganic substances such as metal particles for thermotherapy and radiotherapy, and substances with various pharmacological and therapeutic effects including carriers.
  • the liquid medium for the injection liquid may be any substance suitable for administering these specific substances into the target area, and may be water-based or oil-based.
  • there are no particular limitations on the viscosity of the liquid medium as long as the specific substance can be injected with the needleless syringe 100.
  • the syringe assembly 101 is configured to be detachable from the housing 102.
  • the storage space 2 between the container (the "plastic molded product 1" in this embodiment) and the plunger 103 included in the syringe assembly 101 is filled with the injection liquid in the preparation stage before the needle-free syringe 100 is activated, and the syringe assembly 101 is a unit that is replaced each time the injection liquid is injected.
  • the aforementioned injection target substance passes through the through hole 4 and is injected into the target area of the injection target using the opening 4A as an injection port. That is, in the resin molded product 1, the through hole 4 is defined as a flow path for the injection target substance, and the opening 4A functions as an injection port for the injection target substance.
  • an ignition current is supplied to the igniter 105 based on the operation of the first switch 104A and the second switch 104B, and the injection target substance is injected into the target area without passing through an injection needle.

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  • Mechanical Engineering (AREA)
  • Health & Medical Sciences (AREA)
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  • Moulds For Moulding Plastics Or The Like (AREA)
PCT/JP2023/043896 2023-03-02 2023-12-07 貫通孔を有する樹脂成形品とその成形方法、成形型、及び樹脂成形品を用いた無針注射器 Ceased WO2024180845A1 (ja)

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CN202380094153.4A CN120641258A (zh) 2023-03-02 2023-12-07 具有贯通孔的树脂成型品及其成型方法、成型模具以及使用树脂成型品的无针注射器
EP23925397.4A EP4674590A1 (en) 2023-03-02 2023-12-07 Resin molded product having through-hole, molding method therefor, mold, and needleless syringe using resin molded product

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Citations (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS54180475U (https=) * 1978-06-12 1979-12-20
JPS59122210U (ja) * 1983-02-04 1984-08-17 エヌオーケー株式会社 パイプ状成形品の成形型
JPH11170310A (ja) * 1997-12-05 1999-06-29 Victor Co Of Japan Ltd 射出成形用金型
JP2002521148A (ja) * 1998-07-27 2002-07-16 メディ−ジェクト コーポレイション 医療用注射器組立体用の注射補助プローブ
JP2005511254A (ja) * 2001-12-14 2005-04-28 エフ ホフマン−ラ ロッシュ アクチェン ゲゼルシャフト 無針の皮下注射装置
JP2013166363A (ja) 2012-02-17 2013-08-29 Toppan Printing Co Ltd 微細針チップ射出成形用金型及びその微細針チップを射出成形する方法
JP2017109471A (ja) 2015-12-16 2017-06-22 不二精機株式会社 シリンダ成形用金型及びそれを用いたシリンダ成形方法
WO2020138476A1 (ja) * 2018-12-27 2020-07-02 株式会社ダイセル 無針注射器
US20210307784A1 (en) * 2014-05-07 2021-10-07 Maureen Brown Apparatus including a cylindrical body and a nub

Patent Citations (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS54180475U (https=) * 1978-06-12 1979-12-20
JPS59122210U (ja) * 1983-02-04 1984-08-17 エヌオーケー株式会社 パイプ状成形品の成形型
JPH11170310A (ja) * 1997-12-05 1999-06-29 Victor Co Of Japan Ltd 射出成形用金型
JP2002521148A (ja) * 1998-07-27 2002-07-16 メディ−ジェクト コーポレイション 医療用注射器組立体用の注射補助プローブ
JP2005511254A (ja) * 2001-12-14 2005-04-28 エフ ホフマン−ラ ロッシュ アクチェン ゲゼルシャフト 無針の皮下注射装置
JP2013166363A (ja) 2012-02-17 2013-08-29 Toppan Printing Co Ltd 微細針チップ射出成形用金型及びその微細針チップを射出成形する方法
US20210307784A1 (en) * 2014-05-07 2021-10-07 Maureen Brown Apparatus including a cylindrical body and a nub
JP2017109471A (ja) 2015-12-16 2017-06-22 不二精機株式会社 シリンダ成形用金型及びそれを用いたシリンダ成形方法
WO2020138476A1 (ja) * 2018-12-27 2020-07-02 株式会社ダイセル 無針注射器

Non-Patent Citations (1)

* Cited by examiner, † Cited by third party
Title
See also references of EP4674590A1

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EP4674590A1 (en) 2026-01-07
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