WO2023125902A1 - Stent de nucléation et système de récupération de stent de nucléation - Google Patents

Stent de nucléation et système de récupération de stent de nucléation Download PDF

Info

Publication number
WO2023125902A1
WO2023125902A1 PCT/CN2022/143807 CN2022143807W WO2023125902A1 WO 2023125902 A1 WO2023125902 A1 WO 2023125902A1 CN 2022143807 W CN2022143807 W CN 2022143807W WO 2023125902 A1 WO2023125902 A1 WO 2023125902A1
Authority
WO
WIPO (PCT)
Prior art keywords
sheath
stent
particle
core
proximal
Prior art date
Application number
PCT/CN2022/143807
Other languages
English (en)
Chinese (zh)
Inventor
黄程
林泽丽
刘国良
Original Assignee
先健科技(深圳)有限公司
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by 先健科技(深圳)有限公司 filed Critical 先健科技(深圳)有限公司
Publication of WO2023125902A1 publication Critical patent/WO2023125902A1/fr

Links

Images

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
    • A61N5/00—Radiation therapy
    • A61N5/10—X-ray therapy; Gamma-ray therapy; Particle-irradiation therapy
    • A61N5/1001—X-ray therapy; Gamma-ray therapy; Particle-irradiation therapy using radiation sources introduced into or applied onto the body; brachytherapy
    • A61N5/1002—Intraluminal radiation therapy
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F2/00—Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
    • A61F2/95—Instruments specially adapted for placement or removal of stents or stent-grafts
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
    • A61N5/00—Radiation therapy
    • A61N5/10—X-ray therapy; Gamma-ray therapy; Particle-irradiation therapy
    • A61N5/1001—X-ray therapy; Gamma-ray therapy; Particle-irradiation therapy using radiation sources introduced into or applied onto the body; brachytherapy
    • A61N5/1007—Arrangements or means for the introduction of sources into the body
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
    • A61N5/00—Radiation therapy
    • A61N5/10—X-ray therapy; Gamma-ray therapy; Particle-irradiation therapy
    • A61N2005/1092—Details
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02E—REDUCTION OF GREENHOUSE GAS [GHG] EMISSIONS, RELATED TO ENERGY GENERATION, TRANSMISSION OR DISTRIBUTION
    • Y02E30/00—Energy generation of nuclear origin
    • Y02E30/30—Nuclear fission reactors

Definitions

  • the invention relates to the technical field of interventional medical devices, in particular to particle stents and particle stent recovery systems.
  • the present invention proposes a particle scaffold and a particle scaffold recovery system.
  • the scraping of the particle scaffold to the tube wall of the tissue pipeline is weakened, and it is not easy to cause damage to the tube wall of the tissue pipeline. .
  • the present invention proposes a particle support recovery system, comprising:
  • a particle stent the particle stent includes a stent body, a proximal connector and a distal connector, the stent body includes a hollow tube for containing radioactive substances, the stent body includes a natural state without stress and a stressed Compressed state; recovery device, the recovery device includes a first sheath tube, a first sheath core and a second sheath core, the proximal connector is detachably connected to the first sheath core, and the distal connector is connected to the first sheath core The second sheath core is detachably connected; in the first state, the proximal connector can be pulled by the first sheath core to move away from the distal end, so as to reduce the outer diameter of the stent main body; the second In the second state, the first sheath and the stent main body with reduced outer diameter can be relatively close to allow the particle stent to enter the first sheath.
  • the position of the distal connecting member remains unchanged; or, in the first state, the distal connecting member pulled by the second sheath core and The proximal connector pulled by the first sheath core moves in reverse.
  • the proximal end moves away from the distal end until the stent body is straight.
  • the first sheath core is located at the proximal side of the particle stent, and the second sheath core is located at the distal side of the particle stent.
  • the recovery device further includes a second sheath, and the first sheath, the particle stent, and the second sheath are arranged along the direction from the proximal end to the distal end, passing through The first sheath core of the first sheath is connected to the proximal connector, and the second sheath core passing through the second sheath is connected to the distal connector.
  • both the first sheath core and the second sheath core are located on the proximal side of the particle stent.
  • the recovery device further includes a second sheath, the distal connector faces toward the proximal end, and the first sheath and the second sheath are located at the proximal end of the particle stent. side, and the first sheath and the second sheath are arranged along the radial direction of the particle stent, and the first sheath core passing through the first sheath is connected to the proximal connector , passing through the second sheath core of the second sheath tube and connecting with the distal connecting piece.
  • the proximal end of the first sheath is integrally connected with the second sheath to form a sheath assembly.
  • the first sheath tube and the second sheath tube are integrated to form the sheath tube assembly, and the lumen of the first sheath tube and the inner cavity of the second sheath tube The cavity is connected, and the sheath tube assembly also includes a locator, the locator is installed in the sheath tube assembly, the locator is provided with a first through hole and a second through hole, and the first sheath core passes through the passing through the first sheath tube and the first through hole, and the second sheath core passing through the second sheath tube and the second through hole.
  • the distal connecting member faces the proximal end, and the first sheath is located on the proximal side of the particle stent; the first sheath core passing through the first sheath is connected to the The proximal connector is connected, the first sheath core has a first channel arranged in the axial direction, and the second sheath core passing through the first channel is connected to the distal connector; or, through The second sheath core passing through the first sheath tube is connected to the distal connector, the second sheath core has a second passage arranged in the axial direction, and the first passage passing through the second passage A sheath core is connected to the proximal connector.
  • the stent main body includes a hollow tube for accommodating radioactive substances, and the stent main body includes an unstressed natural state and a stressed compressed state.
  • the proximal end of the stent main body is connected with a proximal connector, and the distal end is connected with a distal connector, the proximal connector is fixedly connected with the first sheath core, and the distal connector is fixedly connected with the second sheath core.
  • the proximal connector can be pulled by the first sheath core to move away from the distal end, thereby reducing the outer diameter of the helical stent main body, so that the resistance between the stent main body and the tube wall of the human tissue pipeline
  • the first sheath and the stent main body with reduced outer diameter move relatively, so that the stent main body enters the first sheath to complete recovery .
  • the resistance between the stent main body and the tube wall of the human tissue pipeline becomes smaller, and even separates from the tube wall of the human tissue pipeline.
  • the scraping of the main body of the bracket against the human tissue pipeline is weakened or even non-scratching, which is not easy to cause damage to the tube wall of the human tissue pipeline.
  • the present invention proposes a particle support, comprising:
  • the particle stent is characterized in that it includes: a stent main body, including a hollow tube for containing radioactive substances, the stent main body includes an unstressed natural state and a stressed compressed state; a connection assembly, the connection assembly includes a The proximal connecting piece at the proximal end of the stent body, and the distal connecting piece connected to the distal end of the stent main body.
  • the proximal connection part is used for detachable connection with the first sheath core of the recovery device and/or the distal connection part is used for detachable connection with the second sheath core of the recovery device .
  • the stent main body's scratching on the human tissue pipeline is weakened or even non-scratching, which is not easy to cause damage to the tube wall of the human tissue pipeline.
  • Fig. 1 is a schematic diagram of a particle scaffold placed in a human tissue pipeline (straight tube) in an embodiment of the present invention
  • Fig. 2 is the schematic diagram that particle support in one embodiment of the present invention is placed in human tissue pipeline (elbow);
  • Fig. 3 is a schematic diagram of a certain moment in the recovery of particle holders in the related art
  • Fig. 4 is a schematic diagram of another moment in which the particle holder is recovered in the embodiment of Fig. 3;
  • Fig. 5 is a schematic diagram of a certain moment in the recovery process of particle holders in an embodiment of the present invention.
  • Fig. 6 is a schematic diagram of another moment in the recovery process of the particle holder in the embodiment of Fig. 5;
  • Fig. 7 is a schematic diagram of a certain moment in the recovery process of particle holders in an embodiment of the present invention.
  • Fig. 8 is a schematic diagram of another moment in the recovery process of the particle holder in the embodiment of Fig. 7;
  • Fig. 9 is a schematic diagram of a certain moment in the recovery process of particle holders in an embodiment of the present invention.
  • Fig. 10 is a schematic diagram of another moment in the recovery process of the particle holder in the embodiment of Fig. 9;
  • Fig. 11 is a schematic diagram of a certain moment in the recovery process of particle holders in an embodiment of the present invention.
  • Fig. 12 is a schematic diagram of another moment in the recovery process of the particle holder in the embodiment of Fig. 11;
  • Fig. 13 is a schematic structural diagram of the first sheath core and the proximal connector in the related art
  • Fig. 14 is a schematic diagram of the structure of the particle stent received in the first sheath in the embodiment of Fig. 13;
  • Fig. 15 is a schematic structural view of the first sheath core and the proximal connector in an embodiment of the present invention.
  • Fig. 16 is a schematic diagram of the structure of the particle stent received in the first sheath in the embodiment of Fig. 15;
  • Fig. 17 is a schematic structural view of the first sheath core and the proximal connector in an embodiment of the present invention.
  • Fig. 18 is a schematic diagram of the structure of the particle stent received in the first sheath in the embodiment of Fig. 17;
  • Fig. 19 is a schematic structural view of the first sheath core and the proximal connector in an embodiment of the present invention.
  • Fig. 20 is a schematic diagram of the structure of the particle stent received in the first sheath in the embodiment of Fig. 19;
  • Fig. 21 is a schematic structural view of the first sheath core and the proximal connector in an embodiment of the present invention.
  • Fig. 22 is a schematic diagram of the structure of the particle stent received in the first sheath in the embodiment of Fig. 21;
  • Fig. 23 is a schematic structural view of the first sheath core and the proximal connector in an embodiment of the present invention.
  • Fig. 24 is a schematic diagram of the structure of the particle stent received in the first sheath in the embodiment of Fig. 23;
  • Fig. 25 is a schematic structural view of the first sheath core and the proximal connector in an embodiment of the present invention.
  • Fig. 26 is a schematic diagram of the structure of the particle stent received in the first sheath in the embodiment of Fig. 25;
  • Fig. 27 is a schematic structural view of the first sheath core and the proximal connector in an embodiment of the present invention.
  • Fig. 28 is a schematic diagram of the structure of the particle stent received in the first sheath in the embodiment of Fig. 27;
  • Fig. 29 is a structural schematic diagram of the hook assembly and the catch head assembly in the embodiment of Fig. 27 .
  • Particle stent 200 Particle stent 200, stent body 210, proximal connector 220, distal connector 230;
  • Card slot 610 insertion slot 611, limit slot 612, block 620, claw 621, limit block 622, first magnetic piece 630, second magnetic piece 640, inlet 641, guide 650;
  • first and second are used for descriptive purposes only, and cannot be interpreted as indicating or implying relative importance or implicitly specifying the quantity of indicated technical features.
  • the features defined as “first” and “second” may explicitly or implicitly include at least one of these features.
  • “plurality” means at least two, such as two, three, etc., unless otherwise specifically defined.
  • the first feature may be in direct contact with the first feature or the first and second feature may be in direct contact with the second feature through an intermediary. touch.
  • “above”, “above” and “above” the first feature on the second feature may mean that the first feature is directly above or obliquely above the second feature, or simply means that the first feature is higher in level than the second feature.
  • “Below”, “beneath” and “beneath” the first feature may mean that the first feature is directly below or obliquely below the second feature, or simply means that the first feature is less horizontally than the second feature.
  • proximal end the end of a medical device implanted in a human or animal body that is closer to the operator
  • distal end the end that is farther from the operator
  • proximal end the end of a medical device implanted in a human or animal body that is closer to the operator
  • distal end the end that is farther from the operator
  • proximal end the end of a medical device implanted in a human or animal body that is closer to the operator
  • distal end the end that is farther from the operator
  • distal end the end that is farther from the operator
  • the particle scaffold 200 provided by an embodiment of the present invention includes a scaffold body 210, the scaffold body 210 is against the inner wall of the tissue pipeline 100 at the implantation position, and is stable by the friction force between the bracket body 210 and the pipeline 100
  • the tissue channel 100 is the channel where the tumor or lesion is located or the channel closest to the tumor.
  • the particle stent 200 carries radioactive substances, and can perform radiation therapy on the lesion. After the treatment is finished, the particle stent 200 is recovered to the sheath by the recovery device, and the sheath is taken out of the body. Referring to Fig. 3 to Fig.
  • the first sheath tube 320 is usually sent into the proximal side of the particle stent 200 in the tissue channel 100, and then the second A sheath core 310 is sent into the first sheath tube 320 , and the first sheath core 310 is connected to the proximal end of the particle stent 200 after passing through the first sheath tube 320 .
  • pulling the first sheath core 310 can drive the particle stent 200 to move from the distal end to the proximal end in the tissue duct 100, and the particle stent 200 gradually deforms and enters the first sheath tube 320, and is held against the first sheath tube 320, thus being stably recovered in the first sheath tube 320.
  • the first sheath tube 320 can be withdrawn from the human body.
  • the first sheath core 310 is always against the inner wall of the tissue duct 100, and will exert pressure on the tissue duct 100. scratches on the inner wall of the tissue duct 100, which may easily cause damage to the inner wall of the tissue duct 100.
  • the particle support recovery system includes a particle support 200 and a recovery device.
  • the stent body 210 is helically formed by a hollow tube.
  • the stent body 210 has elasticity and is used to resist the tube wall of the tissue channel 100 .
  • the lumen of the hollow tube is used to accommodate radioactive substances.
  • a proximal connector 220 is connected to a proximal end of the stent body 210
  • a distal connector 230 is connected to a distal end of the stent body 210 .
  • the recovery device includes a first sheath tube 320, a first sheath core 310 and a second sheath core 410, the proximal connector 220 is detachably connected to the first sheath core 310, and the distal connector 230 is detachably connected to the second sheath core 410 , it is worth noting that when the first sheath core 310 and the second sheath core 410 can be fixedly connected with the proximal connecting member 220 and the distal connecting member 230 respectively, such as by bonding.
  • the particle stent 200 When the particle stent 200 is recovered, it includes the first state and the second state.
  • the proximal connector 220 and the distal connector 230 are respectively connected to the first sheath core 310 and the second sheath core 410, they are in the first state.
  • the proximal connector 220 can be pulled by the first sheath core 310 to move away from the distal end, so as to reduce the outer diameter of the stent body 210 and drive the stent body 210 away from the tissue channel 100 in the radial direction.
  • the first sheath 320 and the stent main body 210 with a reduced outer diameter can be relatively close to allow the particle stent 200 to enter the first sheath 320 .
  • the proximal connector 220 is pulled by the first sheath core 310 to move away from the distal end, the proximal end and the distal end of the stent body 210 are relatively far away, so that the stent body 210 is stretched. While elastically deforming, the outer diameter of the helical stent body 210 decreases, and the stent body 210 leaves the tissue channel 100 in the radial direction.
  • the stent main body 210 In the second state, if the outer diameter of the stent main body 210 is still greater than the inner diameter of the first sheath tube 320 after being reduced, the stent main body 210 will be in the first sheath tube 320 during the relative movement of the first sheath tube 320 and the stent main body 210 . Further elastically deform under the limitation of the tube diameter, so as to enter into the first sheath tube 320 . After entering the first sheath tube 320 , the stent main body 210 elastically resists the inner wall of the first sheath tube 320 .
  • the stent body 210 can directly enter the first sheath tube 320 without contact with the first sheath tube 320.
  • the inner walls of the sheath 320 are in contact.
  • the second state when most of the stent body 210 enters the first sheath tube 320, the fixed relationship between the distal connector 230 and the second sheath core 410 is released, and the first sheath tube 320 and the stent body 210 continue to be relatively close to each other.
  • the particle stent 200 is completely received in the first sheath 320 .
  • the position of the first sheath tube 320 may not change, and the first sheath core 310 and the second sheath core 410 move toward the first sheath tube 320 synchronously, thereby The stent body 210 is moved toward the first sheath 320 .
  • the positions of the first sheath core 310 and the second sheath core 410 may not change, that is, the position of the stent body 210 remains unchanged, and the first sheath tube 320 moves toward the stent body 210 .
  • the first sheath tube 320 and the stent main body 210 may move closer at the same time.
  • the stent body 210 in the first state, the stent body 210 is stretched and elastically deformed, and the outer diameter of the helical stent body 210 decreases, so the resistance between the stent body 210 and the inner wall of the tissue channel 100 becomes smaller, There is even no contact with the inner wall of the tissue duct 100 at all.
  • the second state when the outer diameter of the stent body 210 is reduced, during the relative movement between the first sheath tube 320 and the stent body 210 , if the stent body 210 moves, the stent body 210 will be opposite to the inner wall of the tissue duct 100 The scraping strength is weakened, or even no scraping, so that the tissue pipeline 100 is not easy to be damaged.
  • the position of the distal connecting member 230 does not change. Specifically, in the first state, the position of the second sheath core 410 in the tissue tract 100 remains unchanged, so that the position of the distal connector 230 connected to the second sheath core 410 in the tissue tract 100 remains unchanged.
  • the proximal connector 220 is pulled by the first sheath core 310, the distal position of the particle stent 200 is restricted by the second sheath core 410 and will not move with the proximal end, and the proximal end will gradually move away from the distal end to stretch
  • the stent body 210 is deformed to reduce the outer diameter of the stent body 210 .
  • the distal connecting member 230 pulled by the second sheath core 410 moves in opposite directions to the proximal connecting member 220 pulled by the first sheath core 310 .
  • the second sheath core 410 moves in the direction away from the distal end in the tissue duct 100
  • the first sheath core 310 moves in the direction away from the proximal end in the tissue duct 100 .
  • the proximal connector 220 will be pulled away from the distal end by the first sheath core 310, and at the same time, the distal connector 230 will be pulled away from the proximal end by the second sheath core 410, that is, the proximal end and the distal end of the particle scaffold 200. Simultaneously reverse movement to increase the distance between the proximal end and the distal end to stretch the stent body 210 to deform and reduce the outer diameter of the stent body 210 .
  • the proximal end moves away from the distal end until the stent body 210 is straight.
  • the proximal end and the distal end of the stent body 210 are relatively far away, so that the stent body 210 is stretched and elastically deformed, the outer diameter of the helical stent body 210 decreases, and the stent body 210
  • the resisting force with the inner wall of the tissue duct 100 becomes smaller, and even no contact with the inner wall of the tissue duct 100 at all.
  • the degree of tensile deformation is large, and the stent body 210 is pulled from a helical shape to a straight tube shape, so that it does not contact the inner wall of the tissue duct 100 at all.
  • the stent body 210 in the second state, during the relative movement between the first sheath tube 320 and the stent body 210, if the stent body 210 moves, the stent body 210 will not contact the inner wall of the tissue duct 100, so as not to scrape the tissue duct 100 damage to the inner wall.
  • the first sheath core 310 is located at the proximal side of the particle stent 200
  • the second sheath core 410 is located at the distal side of the particle stent 200 .
  • the first sheath core 310 and the second sheath core 410 enter the body from different positions of the human body, for example, one of them enters from the leg, and the other enters from the neck.
  • the recovery device further includes a second sheath tube 420, the first sheath tube 320, the particle stent 200, and the second sheath tube 420 are arranged along the direction from the proximal end to the distal end, and pass through the first sheath tube 420.
  • the first sheath core 310 of the sheath tube 320 is connected to the proximal connector 220
  • the second sheath core 410 passing through the second sheath 420 is connected to the distal connector 230 .
  • the first sheath tube 320 and the second sheath tube 420 enter the body from different positions of the human body, the first sheath core 310 passes through the first sheath tube 320 and is fixedly connected to the proximal connector 220, and the second sheath core 410 After passing through the second sheath tube 420 , it is fixedly connected to the distal connecting member 230 .
  • the first sheath core 310 and the second sheath core 410 can move in reverse synchronously, that is, the first sheath The core 310 and the second sheath core 410 only need to move in opposite directions along the respective directions of extending into the human body.
  • both the first sheath core 310 and the second sheath core 410 are located on the proximal side of the particle stent 200 .
  • the first sheath core 310 and the second sheath core 410 can enter the body from the same position of the human body, for example, both enter from the legs, or both enter from the neck. Accessing the body from the same location can make the operation more convenient and require fewer incisions in the body.
  • the recovery device further includes a second sheath 420 , the distal connector 230 faces toward the proximal end, and the first sheath 320 and the second sheath 420 are located on the particle stent 200
  • the proximal side of the first sheath tube 320 and the second sheath tube 420 are arranged along the radial direction of the particle stent 200, the first sheath core 310 passing through the first sheath tube 320 is connected to the proximal connector 220, and the The second sheath core 410 passing through the second sheath tube 420 is connected to the distal connecting member 230 .
  • first sheath 320 and the second sheath 420 extend into the tissue duct 100 from the same position, the first sheath core 310 is detachably connected to the proximal connector 220 after passing through the first sheath 320, and the second sheath The core 410 is detachably connected to the distal connecting member 230 after passing through the second sheath tube 420 .
  • the position on the distal connecting member 230 for connecting with the second sheath core 410 is toward the proximal end, so that the second sheath core 410 protruding from the proximal side can be detachably connected with the distal connecting member 230 .
  • the first sheath core 310 and the second sheath core 410 can move in reverse synchronously, that is, the first sheath
  • the core 310 moves in the opposite direction of the direction of inserting into the human body
  • the second sheath core 410 moves along the direction of inserting into the human body.
  • the first sheath 320 is integrated with the second sheath 420 to form a sheath assembly.
  • the first sheath tube 320 and the second sheath tube 420 are fixedly connected as one, or the two are directly integrally formed into one part. After the two are integrated, the inner cavities of the two can still be in a separate state, or the inner cavities of the two can communicate with each other. Such arrangement can further simplify the structure of the recovery device, and simultaneously simplify the operation steps, without extending two independent sheath tubes into the body.
  • the first sheath tube 320 and the second sheath tube 420 are integrated to form a sheath tube assembly, and the lumen of the first sheath tube 320 and the inner cavity of the second sheath tube 420 cavities connected.
  • the sheath tube assembly also includes a locator 500, the locator 500 is installed in the sheath tube assembly, the locator 500 is provided with a first through hole 510 and a second through hole 520, and the first sheath core 310 passes through the first sheath tube 320 and the second through hole 520.
  • the first through hole 510 , and the first sheath core 310 can rotate in the first through hole 510 .
  • the second sheath core 410 passes through the second sheath tube 420 and the second through hole 520 , and the second sheath core 410 can rotate in the second through hole 520 .
  • the positioning member 500 is installed in the lumen of the sheath assembly, and is located near one end of the particle stent 200 .
  • a part of the positioning member 500 is located in the lumen of the first sheath tube 320, and a part is located in the inner cavity of the second sheath tube 420.
  • the positioning member 500 can be installed in various ways such as bonding, clamping or integral molding.
  • first sheath tube 320 and the second sheath tube 420 are both in the shape of a round tube, and the two communicate through their respective side walls, then the formed sheath tube assembly is approximately in the shape of a hollow gourd or "8", and the positioning member 500 is also Set to the corresponding shape.
  • the first sheath tube 320 and the second sheath tube 420 can also jointly form a round tube-shaped sheath tube assembly, and each of the first sheath tube 320 and the second sheath tube 420 occupies half of the area of the round tube.
  • the structure of the recovery device can be further simplified, and the operation steps can be simplified at the same time, without extending two independent sheath tubes into the body; at the same time, through
  • the positioner 500 is provided to limit the position of the first sheath core 310 and the second sheath core 410 , so that they can move independently after extending out of the sheath tube assembly, and are less likely to interfere with each other due to collision and entanglement.
  • the distal connector 230 faces the proximal end, the first sheath 320 is located on the proximal side of the particle stent 200; the first sheath core 310 passing through the first sheath 320 Connected with the proximal connecting member 220 , the first sheath core 310 has a first channel arranged in the axial direction, and the second sheath core 410 passing through the first channel is connected with the distal connecting member 230 .
  • the first sheath core 310 is also used as the second sheath tube 420 , that is, the first sheath core 310 is provided with a first channel penetrating in the axial direction for the second sheath core 410 to pass through.
  • Such setting can eliminate the need to separately arrange the second sheath tube 420, which can simplify the structure of the recovery device, and simplify the operation steps simultaneously, without stretching into two independent sheath tubes in the body.
  • the distal connecting member 230 faces the proximal end, and the first sheath 320 is located on the proximal side of the particle stent 200; the second sheath core 410 passing through the first sheath 320 and the distal connecting member 230 , the second sheath core 410 has a second channel arranged in the axial direction, and the first sheath core 310 passing through the second channel is connected to the proximal connector 220 .
  • the second sheath core 410 is provided with a second channel penetrating in the axial direction for the first sheath core 310 to pass through.
  • the particle scaffold 200 is used to be placed in the tissue duct 100.
  • the particle scaffold 200 includes a scaffold body 210 and a connecting component.
  • the scaffold body 210 is formed by a hollow tube spirally surrounded by a hollow tube.
  • the scaffold body 210 has elasticity for resisting As for the tube wall of the tissue duct 100, the lumen of the hollow tube is used to accommodate radioactive substances.
  • the connection assembly includes a proximal connector 220 connected to the proximal end of the stent main body 210, and a distal connector 230 connected to the distal end of the stent main body 210.
  • the proximal connector 220 is used to connect with the first sheath core 310 of the recovery device.
  • the distal connection part 230 is used to connect with the second sheath core 410 of the recovery device.
  • the proximal connector 220 can be pulled by the first sheath core 310 to move away from the distal end, so as to reduce the outer diameter of the stent body 210 .
  • the stent main body 210 with reduced outer diameter can move relative to the first sheath 320 so that the particle stent 200 enters the first sheath 320 .
  • the particle rack 200 in this embodiment is the particle rack 200 in each embodiment of the aforementioned particle rack recovery system.
  • the recovery method of the particle support 200 includes the following steps:
  • S100 connect the first sheath core 310 to the proximal end of the particle stent 200, and connect the second sheath core 410 to the distal end of the particle stent 200;
  • S200 pull the proximal end at least through the first sheath core 310 to move away from the distal end, so as to reduce the outer diameter of the helical particle stent 200;
  • S300 make the particle scaffold 200 relatively close to the first sheath 320 until the particle scaffold 200 enters the first sheath 320 .
  • the radial dimension of the sheath core is smaller than the radial dimension of the sheath tube passing through , so as to ensure that the sheath core can penetrate as freely as possible in the sheath tube, and is not easily hindered by the friction of the inner wall of the sheath tube.
  • first sheath core 310 it is necessary to connect the first sheath core 310 to the proximal connector 220, and connect the second sheath core 410 to the distal connector 230.
  • the following embodiments are for the first sheath core 310 and the proximal connector 220 fixed structure is introduced.
  • the particle support recovery system includes a particle support 200 and a recovery device, and the particle support 200 can be placed in the human body
  • the recovery device can be used to recover the particle scaffold 200 into the corresponding sheath tube.
  • the particle stent 200 includes a stent main body 210 and a proximal connector 220.
  • the stent main body 210 is helically surrounded by a hollow tube.
  • the stent main body 210 is elastic and is used to resist the tube wall of the tissue channel 100.
  • the lumen of the hollow tube is used for
  • the proximal end of the stent main body 210 is connected with a proximal connector 220 for containing radioactive substances.
  • the recovery device includes a first sheath 320, a first sheath core 310 and a first fixing member 330, the first fixing member 330 is connected to the first sheath core 310, the first sheath core 310 passes through the first sheath tube 320, and the first fixing member 330 The member 330 is connected to the proximal connecting member 220 .
  • one of the first fixing member 330 and the proximal connecting member 220 at least partially extends into the other, and the particle stent 200 can be axially pulled by the first sheath core 310 to be received in the first sheath tube 320 .
  • the first fixing member 330 can be fixedly installed on the end of the first sheath core 310 by means of screw connection, clamping, bonding, integral molding and the like. Specifically, along the axial direction of the particle stent 200 , one part of the first fixing part 330 and the proximal connecting part 220 protrudes into the other, or all protrudes into the other. In this embodiment, along the axial direction of the particle stent 200 , one of the first fixing member 330 and the proximal connecting member 220 at least partially protrudes into the other, that is, there is an overlapping area between the two in the axial direction.
  • this intrusive connection structure can ensure a larger contact area between the first fixing part 330 and the proximal connecting part 220, thereby enhancing the firmness of the connection structure. property, so that the particle support 200 is not easy to loose, so that it is not easy to damage the tissue channel 100 due to falling and colliding with the inner wall of the tissue channel 100 .
  • a threaded hole can be provided at the end of the proximal connecting member 220, and an external thread can be provided on the outer wall of the first fixing member 330, and the first fixing member 330 can extend into the threaded hole,
  • the first fixing part 330 is fixed on the proximal connecting part 220 through screw connection. After the first sheath core 310 is stretched into the threaded hole entrance, only need to rotate the first sheath core 310, the first fixing part 330 can be screwed into the threaded hole to realize the connection. When the fixed relationship needs to be released, it is only necessary to reversely rotate the first sheath core 310 .
  • the positions of the threaded holes may also be exchanged, a threaded hole is provided at the end of the first fixing member 330 , and an external thread is provided on the outer wall of the proximal connecting member 220 .
  • the first fixing member 330 and the proximal connecting member 220 are provided with a slot 610, and the other is provided with a block 620, and the block 620 is arranged along the shaft. Extends into the card slot 610 and elastically resists the slot wall of the card slot 610 .
  • the end of the proximal connecting member 220 is provided with a locking groove 610
  • the first fixing member 330 includes a locking block 620
  • the locking block 620 can be elastically deformed in the radial direction.
  • the positions of the locking block 620 and the locking slot 610 can be exchanged.
  • the clamping block 620 When the first sheath core 310 is relatively close to the proximal connecting member 220 , the clamping block 620 will protrude into the clamping groove 610 and be elastically deformed by the support of the groove wall of the clamping groove 610 to realize the connection. After the connection, the clamping block 620 extends into the clamping slot 610 and is wrapped by the clamping slot 610, so that it is not easy to withdraw from the clamping slot 610, which can improve the firmness of the connection.
  • the clamping block 620 and the clamping slot 610 can be selected from any structure capable of elastic clamping in the prior art.
  • the clamping block 620 includes a clamping claw 621 and a limiting block 622 protruding radially outward from the clamping claw 621
  • the clamping slot 610 includes an extending slot 611 extending in the axial direction
  • the limiting slot 612 radially extends outward from the side wall of the protruding slot 611 .
  • the limiting block 622 will slide along the groove wall extending into the groove 611 until it is snapped into the limiting groove 612 to be fixed.
  • the limiting block 622 When the limiting block 622 is snapped into the limiting groove 612 , it will elastically resist against the groove wall of the limiting groove 612 .
  • the stopper 622 When the fixed relationship needs to be released, it is only necessary to pull the first sheath core 310 in the opposite direction, so that the stopper 622 is further elastically deformed, and gradually withdraws from the stopper groove 612, and again bears against the groove wall extending into the groove 611, and along the extension The wall of the groove 611 slides to exit the groove 611 .
  • the entrance of the protruding groove 611 may be set in a tapered shape, that is, along the protruding direction, the radial dimension of the entrance of the protruding groove 611 decreases gradually, so as to facilitate the entry of the locking block 620 .
  • the limiting block 622 is configured in a wedge shape, and along the direction in which the limiting block 622 snaps into the limiting slot 612 (ie radially outward), the axial dimension of the limiting block 622 decreases gradually.
  • the limiting groove 612 is also configured in a wedge shape.
  • the wedge-shaped block cooperates with the wedge-shaped groove through the inclined surface, which can facilitate the withdrawal of the limiting block 622 from the limiting groove 612 .
  • the locking block 620 is in a "V" shape, and the locking block 620 includes radially symmetrically distributed claws 621 , and a limiting block 622 protruding radially outward from each claw 621 .
  • the engaging slot 610 includes an extending slot 611 extending axially, and two limiting slots 612 extending radially outward from the sidewall of the extending slot 611 , and the two limiting slots 612 are radially symmetrically distributed.
  • each limiting block 622 snaps into the corresponding limiting groove 612 to achieve fixing.
  • the first sheath core 310 includes a first inner sheath core 311 and a first outer sheath core 312, the first outer sheath core 312 passes through the first sheath tube 320, and the first inner sheath core 311 passes through Through the first outer sheath core 312 , the first fixing member 330 is connected to the end of the first inner sheath core 311 .
  • the first inner sheath core 311 does not protrude from the first outer sheath core 312, and the block 620 in the first fixing member 330 elastically resists Hold on the inner wall of the first outer sheath core 312.
  • the first fixing member 330 is directly fixed to the end of the first sheath core 310 without setting the inner and outer sheath cores.
  • the first fixing member 330 is provided with a first magnetic member 630
  • the proximal connecting member 220 is provided with a second magnetic member 640
  • the first magnetic member 630 and the second magnetic member The magnetic poles of the pieces 640 are oppositely set, so that the two magnetisms are opposite.
  • the end of the second magnetic member 640 is provided with a recessed groove, and the first magnetic member 630 protrudes outward from the main body of the first fixing member 330 to form a bump.
  • the first fixing part 330 is relatively close to the proximal connecting part 220, the first magnetic part 630 snaps into the groove at the end of the second magnetic part 640, and at the same time, the first magnetic part 630 and the second magnetic part 640 pass between the two.
  • the magnetic connection between them Fast positioning can be carried out during the connection process through the cooperation of the groove and the protrusion, and, after the connection, the first magnetic part 630 extends into the second magnetic part 640 and is wrapped by the second magnetic part 640, which can increase the magnetic field of the two.
  • the groove can be set in a tapered shape, that is, along the extending direction, the radial dimension of the groove decreases gradually, so as to facilitate the entry of the first magnetic member 630.
  • the first magnetic piece 630 may also be set in a concave shape, and the second magnetic piece 640 may be set in a convex shape, and the second magnetic piece 640 is wrapped by the first magnetic piece 630 .
  • a first magnetic part 630 is provided on the first fixing part 330
  • a second magnetic part 640 is provided on the proximal connecting part 220
  • the first magnetic part 630 and The second magnetic part 640 is magnetically opposite.
  • the first fixing part 330 is relatively close to the proximal connecting part 220
  • the first magnetic part 630 and the second magnetic part 640 are attracted.
  • one of them is provided with a card slot 610
  • the other is provided with a card block 620
  • the card block 620 extends into the card slot 610 in the axial direction and elastically resists on the groove wall of the card groove 610 .
  • the end of the proximal connecting member 220 is provided with a locking groove 610
  • the first fixing member 330 includes a locking block 620
  • the locking block 620 can be elastically deformed in the radial direction.
  • the clamping block 620 will protrude into the clamping groove 610 and be elastically deformed by the support of the groove wall of the clamping groove 610 to realize the connection.
  • the clamping block 620 extends into the clamping slot 610 and is wrapped by the clamping slot 610, so that it is not easy to withdraw from the clamping slot 610, which can improve the firmness of the connection.
  • the block 620 includes a claw 621 and a limiting block 622 extending radially outward from the claw 621
  • the slot 610 includes an extending slot 611 extending in the axial direction, and a stop extending from the extending slot 611
  • the limiting groove 612 extending radially outward on the side wall.
  • the limiting block 622 With the first sheath core 310 and As the proximal connecting piece 220 continues to approach relatively, the limiting block 622 will slide along the groove wall extending into the groove 611 until it is snapped into the limiting groove 612 to be fixed. When the limiting block 622 is snapped into the limiting groove 612 , it will elastically resist against the groove wall of the limiting groove 612 .
  • the first fixing part 330 is relatively close to the proximal connecting part 220 , the first magnetic part 630 and the second magnetic part 640 are connected by the magnetic force between them.
  • double fixing can be achieved through the cooperation of the clamping structure and the magnetic attraction structure, which can further improve the firmness of the fixing structure of the first fixing part 330 and the proximal connecting part 220 .
  • the first sheath core 310 includes a first inner sheath core 311 and a first outer sheath core 312, the block 620 is connected to the first inner sheath core 311, and the first magnetic member 630 is connected to the first The outer sheath core 312, the block 620 passes through the first outer sheath core 312 and the first magnetic part 630, and the second magnetic part 640 is provided with an introduction port 641 communicating with the draw groove 610, when the first fixing part 330 and the proximal end The connecting pieces 220 are relatively close, the clamping block 620 extends into the clamping slot 610 through the inlet 641 , and the second magnetic component 640 is sleeved on the first magnetic component 630 .
  • the first outer sheath core 312 passes through the first sheath tube 320
  • the first inner sheath core 311 passes through the first outer sheath core 312
  • the first fixing part 330 is connected to the end of the first inner sheath core 311
  • the first magnetic part 630 is connected to the end of the first outer sheath core 312 .
  • the second magnetic member 640 is in a concave shape to form an inlet 641 inside.
  • double fixation can be achieved through the cooperation of the clamping structure and the magnetic attraction structure, which can further improve the firmness of the fixing structure of the first fixing part 330 and the proximal connecting part 220; at the same time, the introduction formed by the second magnetic part 640
  • the opening 641 can guide the clamping of the clamping block 620, and can realize quick positioning during connection.
  • a guide piece 650 is also included.
  • the radial dimension of the guide member 650 gradually decreases, and when the first fixing member 330 is relatively close to the proximal connecting member 220 , the guide member 650 is resisted by the inner wall of the first sheath tube 320 and deformed and bent.
  • the guide piece 650 is in the shape of a hollow cone, and the guide piece 650 is sheathed at the entrance of the slot 610 .
  • the guide part 650 When the first fixing part 330 is relatively close to the proximal connecting part 220, and the particle stent 200 is gradually drawn into the first sheath tube 320, the guide part 650 will be held against by the diameter of the first sheath tube 320 and move toward The direction away from the first sheath tube 320 is elastically deformed and bent, which will not affect the recovery of the particle scaffold 200 .
  • the guide piece 650 By setting the guide piece 650, the snap-in of the clamping block 620 can be guided and quickly positioned, so that the fastening can be completed quickly.
  • a similar guiding structure can also be provided in the above manner.
  • At least one of the first fixing member 330 and the proximal connecting member 220 includes a hook 710, and the first fixing member 330 and the proximal connecting member 220 hang catch.
  • the first fixing member 330 includes a first hook
  • the proximal connecting member 220 includes a second hook
  • the first hook is hooked to the second hook.
  • a hook 710 protrudes outward from the end of the first fixing member 330
  • a hook 710 protrudes outward from the end of the proximal connecting member 220
  • the two hooks 710 are hooked to achieve fixation.
  • the hook 710 shown in the drawings is a plan view, in fact, one of the hooks 710 is provided with a baffle parallel to the paper, for example, the hook 710 provided at the end of the proximal connector 220 is on the paper.
  • the inner side is provided with a baffle plate parallel to the paper surface, and when the first fixing member 330 rotates toward the inside of the paper surface, the hook 710 provided at the end of the first fixing member 330 will be blocked by the baffle plate, thereby preventing the two hooks 710 from loosening. take off.
  • the first sheath core 310 can be rotated toward the inside of the paper while pulling the particle holder 200 to make the two hooks 710 close together.
  • the helical direction of the particle holder 200 needs to be considered, and it is necessary to ensure that the helix of the particle holder 200 can be dispersed when the first sheath core 310 rotates toward the inside of the paper.
  • the helical spreading fingers transform the original helical particle scaffold 200 into a straight tube by twisting.
  • the shape of the hook 710 is not limited thereto, and other structures capable of achieving similar functions are also available.
  • the two hooks 710 when the two hooks 710 are hooked, the one provided with the baffle surrounds the other half, which can prevent the two hooks 710 from loosening, and the connection is more firm.
  • one of the first fixing member 330 and the proximal connecting member 220 includes a hook 710 , and the other includes a pull wire 720 , and the pull wire 720 is hooked to the hook 710 .
  • the end of the first fixing member 330 is provided with an outwardly protruding hook 710
  • the end of the proximal connecting member 220 is provided with an outwardly protruding hook 710.
  • a plurality of drag cables 720 surround a spherical shape. When the first fixing part 330 is relatively close to the proximal connecting part 220, the hook 710 can pass through the drag cables 720 and extend between the drag cables 720 to realize hanging catch.
  • the positions of the hook 710 and the cable 720 can be interchanged.
  • the end of the first fixing member 330 is provided with a pulling cable 720 protruding outward, the pulling cable 720 forms a closed loop, and the end of the proximal connecting member 220 is arranged There is a hook 710 protruding outward.
  • the pull cable 720 can be put on the hook 710, so as to realize the hooking.
  • the drag cable 720 can be tightly set on the hook 710, so that it is not easy to loosen.
  • two hooks 710 protruding outward are provided at the end of the proximal connecting member 220, and the two hooks 710 are symmetrically distributed along the radial direction.
  • the end of the first fixing part 330 is provided with two pulling cables 720 protruding outward.
  • each pulling cable 720 can be placed on the corresponding hook 710, so as to realize the hooking.
  • the interior of the first sheath core 310 is hollow, a main cable passes through the first sheath core 310 , and is branched into two cable 720 at the end of the first sheath core 310 .
  • the lumen end of the first sheath core 310 is provided with a component similar to the aforementioned positioning member 500 in FIG. 9 , and the component is provided with two through holes for passing two pull cables 720 respectively.
  • the radial dimension of the hook 710 gradually increases, that is, a slope is formed on the hook 710, so that the pull cable 720 can slide and guide along the slope, so as to complete the hooking.
  • one of the first fixing member 330 and the proximal connecting member 220 includes a hook assembly
  • the other includes a catch head assembly
  • the hook assembly includes a plurality of circumferentially spaced
  • the hook 710 and the catch head assembly include a connecting rod 730 and a catch head 740 connected to the end of the connecting rod 730 , and the catch head 740 is hooked between two adjacent hooks 710 .
  • the end of the proximal connecting member 220 is provided with a hook assembly protruding outward, and the hook assembly is in the shape of a flower-shaped grab head.
  • the outer end of the first fixing member 330 is provided with a catch head assembly, and the catch head assembly includes a plurality of connecting rods 730 arranged in the circumferential direction, and a spherical catch head 740 is connected to the end of each connecting rod 730 .
  • the root gap of the adjacent hooks 710 is smaller than the diameter of the catch head 740 , when the first fixing part 330 is relatively close to the proximal connecting part 220 , the catch head 740 will protrude between the adjacent hooks 710 and realize hooking.
  • the positions of the hook assembly and the catch head assembly can be interchanged.
  • the recovery device further includes a second fixing part, the second fixing part is connected with the second sheath core 410, the second fixing part is connected with the distal connecting part 230, along the axial direction of the particle stent 200, the second fixing part One of the member and the distal connecting member 230 extends at least partially into the other.
  • the connection structure between the second sheath core 410 and the distal connector 230 can be selected from any one of the fixing structures between the first sheath core 310 and the proximal connector 220 in the foregoing embodiments, which will not be repeated here.

Landscapes

  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Biomedical Technology (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Radiology & Medical Imaging (AREA)
  • Pathology (AREA)
  • Cardiology (AREA)
  • Oral & Maxillofacial Surgery (AREA)
  • Transplantation (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Vascular Medicine (AREA)
  • Media Introduction/Drainage Providing Device (AREA)
  • Radiation-Therapy Devices (AREA)

Abstract

L'invention concerne un stent de nucléation (200) et un système de récupération de stent de nucléation. Le système de récupération de stent de nucléation comprend : un stent de nucléation (200), le stent de nucléation (200) comprenant un corps principal de stent (210), un élément de liaison proximal (220), et un élément de liaison distal (230), et le corps principal de stent (210) comprenant un tube creux pour recevoir une substance radioactive ; un dispositif de récupération, le dispositif de récupération comprenant un premier tube de gaine (320), un premier cœur de gaine (310) et un second cœur de gaine (410) ; l'élément de liaison proximal (220) est relié de manière fixe au premier cœur de gaine (310), et l'élément de liaison distal (230) est relié de manière fixe au second cœur de gaine (410) ; dans un premier état, l'élément de liaison proximal (220) peut être tiré par le premier cœur de gaine (310) pour s'éloigner de l'extrémité distale, de façon à réduire un diamètre externe du corps principal de stent (210) ; et dans un second état, le premier tube de gaine (320) et le corps principal de stent (210) ayant un diamètre externe réduit peuvent s'approcher l'un de l'autre pour amener le stent de nucléation (200) à entrer dans le premier tube de gaine (320). Lorsque le stent de nucléation (200) est récupéré dans le premier tube de gaine (320), le stent de nucléation (200) n'est pas sujet à racler contre une paroi d'un tractus tissulaire (100), et n'est pas sujet à provoquer un endommagement de la paroi du tractus tissulaire (100).
PCT/CN2022/143807 2021-12-31 2022-12-30 Stent de nucléation et système de récupération de stent de nucléation WO2023125902A1 (fr)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
CN202111673738.0 2021-12-31
CN202111673738.0A CN116407746A (zh) 2021-12-31 2021-12-31 粒子支架和粒子支架回收系统

Publications (1)

Publication Number Publication Date
WO2023125902A1 true WO2023125902A1 (fr) 2023-07-06

Family

ID=86998098

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/CN2022/143807 WO2023125902A1 (fr) 2021-12-31 2022-12-30 Stent de nucléation et système de récupération de stent de nucléation

Country Status (2)

Country Link
CN (1) CN116407746A (fr)
WO (1) WO2023125902A1 (fr)

Citations (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5484384A (en) * 1991-01-29 1996-01-16 Med Institute, Inc. Minimally invasive medical device for providing a radiation treatment
CN2783951Y (zh) * 2005-02-01 2006-05-31 维科医疗器械(苏州)有限公司 一种可用于回收保护伞的自膨式支架同轴释放系统
CN103190967A (zh) * 2013-03-15 2013-07-10 杭州启明医疗器械有限公司 一种介入器械输送系统及其鞘芯
US20170042615A1 (en) * 2010-05-12 2017-02-16 Amr Salahieh Ablation catheters
US20170296266A1 (en) * 2008-11-11 2017-10-19 Amr Salahieh Ablation catheters
CN113440323A (zh) * 2020-03-26 2021-09-28 深圳市先健畅通医疗有限公司 支架装配系统及支架装配方法

Patent Citations (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5484384A (en) * 1991-01-29 1996-01-16 Med Institute, Inc. Minimally invasive medical device for providing a radiation treatment
CN2783951Y (zh) * 2005-02-01 2006-05-31 维科医疗器械(苏州)有限公司 一种可用于回收保护伞的自膨式支架同轴释放系统
US20170296266A1 (en) * 2008-11-11 2017-10-19 Amr Salahieh Ablation catheters
US20170042615A1 (en) * 2010-05-12 2017-02-16 Amr Salahieh Ablation catheters
CN103190967A (zh) * 2013-03-15 2013-07-10 杭州启明医疗器械有限公司 一种介入器械输送系统及其鞘芯
CN113440323A (zh) * 2020-03-26 2021-09-28 深圳市先健畅通医疗有限公司 支架装配系统及支架装配方法

Also Published As

Publication number Publication date
CN116407746A (zh) 2023-07-11

Similar Documents

Publication Publication Date Title
CN101917916B (zh) 导管隧道器
JP5347175B2 (ja) 導入器
JP5000657B2 (ja) ワイヤレス牽引先端を有するｐｅｇチューブ
US20040225233A1 (en) Magnetic guidewires
CN102793597A (zh) 支架输送系统
BRPI0618119A2 (pt) dispositivos de acoplamento, liberação e métodos para sua montagem e uso
BR112016015419B1 (pt) Implante para incisão para a criação de incisões na uretra prostática de um sujeito
JP2008229366A (ja) ワイヤー越しインターロック装着／分離機構
KR101442062B1 (ko) 결석 제거 기구
JP7146876B2 (ja) 楕円形状を部分的に有する、再搭載可能な止血クリップ装置の為のカプセル
GB2509952A (en) Medical device holder for a loading and carrier assembly
CN109700487B (zh) 输送器和输送系统
KR102536177B1 (ko) 결석 적출 메쉬 바스켓 및 결석 적출 메쉬 바스켓에 사용되는 더블 캐비티 엔드캡
US10881831B2 (en) Endoscopic basket delivery catheter
WO2023125902A1 (fr) Stent de nucléation et système de récupération de stent de nucléation
MX2022016284A (es) Instrumento de acceso vascular y dispositivos y metodos relacionados.
US10898681B2 (en) Endoscopic cannulating devices and methods of use
WO2013154754A1 (fr) Systèmes, dispositifs et procédés de fixation distale d'un dispositif médical
CA3056025A1 (fr) Systemes et procedes pour echange de dispositif dans une procedure endoscopique
CN116407778A (zh) 回收系统
JPWO2003092782A1 (ja) 留置チューブガイド装置
CN114224422A (zh) 一种配合内窥镜使用的无磁止血夹
US20140343539A1 (en) Apparatuses for providing proximal guide wire control, systems including the same and methods for installing elongated medical devices onto guide wires
CN2862982Y (zh) 一种植入性分流管及置入该分流管用的配套置入器
US20210228199A1 (en) Access device having an anchoring feature and methods of using the same

Legal Events

Date Code Title Description
121 Ep: the epo has been informed by wipo that ep was designated in this application

Ref document number: 22915151

Country of ref document: EP

Kind code of ref document: A1