WO2021254512A1 - Tube-breaking structure, biochemical test tube and heat-conducting blind tube - Google Patents

Tube-breaking structure, biochemical test tube and heat-conducting blind tube Download PDF

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Publication number
WO2021254512A1
WO2021254512A1 PCT/CN2021/101111 CN2021101111W WO2021254512A1 WO 2021254512 A1 WO2021254512 A1 WO 2021254512A1 CN 2021101111 W CN2021101111 W CN 2021101111W WO 2021254512 A1 WO2021254512 A1 WO 2021254512A1
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WO
WIPO (PCT)
Prior art keywords
tube
broken
broken pipe
biochemical test
pipe
Prior art date
Application number
PCT/CN2021/101111
Other languages
French (fr)
Chinese (zh)
Inventor
许向华
戎振洋
喻晴
陈翔
周中人
Original Assignee
上海快灵生物科技有限公司
上海妙灵生物工程有限公司
上海金标生物科技有限公司
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from CN202120200347.6U external-priority patent/CN214278192U/en
Priority claimed from CN202110097129.9A external-priority patent/CN112858658B/en
Priority claimed from CN202110194027.9A external-priority patent/CN114958562A/en
Application filed by 上海快灵生物科技有限公司, 上海妙灵生物工程有限公司, 上海金标生物科技有限公司 filed Critical 上海快灵生物科技有限公司
Publication of WO2021254512A1 publication Critical patent/WO2021254512A1/en

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Classifications

    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01LCHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L3/00Containers or dishes for laboratory use, e.g. laboratory glassware; Droppers
    • B01L3/50Containers for the purpose of retaining a material to be analysed, e.g. test tubes
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B26HAND CUTTING TOOLS; CUTTING; SEVERING
    • B26FPERFORATING; PUNCHING; CUTTING-OUT; STAMPING-OUT; SEVERING BY MEANS OTHER THAN CUTTING
    • B26F1/00Perforating; Punching; Cutting-out; Stamping-out; Apparatus therefor
    • B26F1/38Cutting-out; Stamping-out
    • B26F1/44Cutters therefor; Dies therefor
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12MAPPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
    • C12M1/00Apparatus for enzymology or microbiology
    • C12M1/24Apparatus for enzymology or microbiology tube or bottle type
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing

Definitions

  • the invention relates to the technical field of biochemical detection devices, in particular to a broken tube structure, a biochemical test tube and a heat-conducting blind tube.
  • test tube When performing in vitro diagnosis or in vitro testing, in order to obtain qualitative results quickly, a combination of chromatography test paper and test tube is usually used as a rapid diagnostic tool or rapid detection tool. Generally speaking, the samples for diagnosis or testing usually have some dangers, such as certain toxicity and infectiousness. The used test tubes will be treated as medical waste.
  • test tube in the related art has some defects. For example, in the detection, the preparation of the reaction solution, sampling and other operations are required, which is time-consuming and labor-intensive. In addition, during testing, most of the samples to be tested are exposed, which is likely to endanger the health of the testing personnel. If a throat swab is used to collect samples for new coronavirus testing, the throat swab will be directly exposed to the air, or temporarily stored in a sealed container; when testing, the throat swab is taken out of the sealed container and placed in the testing device. Perform testing. In the process of removing the throat swab, the brief exposure of the throat swab increases the risk of infection of the inspector.
  • the purpose of the present invention is to provide a broken tube structure, a biochemical test tube, and a heat-conducting blind tube in view of the deficiencies in the prior art, so as to at least solve the problems of low detection efficiency and high infection risk in related technologies.
  • a broken pipe structure including:
  • At least two broken pipe parts are arranged above the body, and the broken pipe parts include:
  • a cutting element, the cutting element is arranged above the broken pipe component
  • the expansion element is arranged below the broken pipe part and connected with the cutting element;
  • the flow guiding part is arranged between two adjacent broken pipe parts.
  • the broken pipe component includes:
  • the first pipe breaking component, the first pipe breaking component includes:
  • a first cutting element, the first cutting element is arranged above the first pipe breaking component
  • a first expansion element, the first expansion element is arranged below the first pipe breaking component, located below the first cutting element, and connected to the first cutting element;
  • the second pipe breaking component, the second pipe breaking component includes:
  • a second cutting element, the second cutting element is arranged above the second pipe breaking component
  • a third cutting element, the third cutting element is arranged above the second pipe breaking component, located below the second cutting element, and connected to the second cutting element;
  • the second expansion element, the second expansion element is arranged under the second pipe breaking component, located under the third cutting element, and connected with the third cutting element.
  • it further includes:
  • the connecting part is arranged inside the main body and communicates with the outside of the main body.
  • the longitudinal section of the connecting member is convex.
  • it further includes:
  • the first fitting member is provided on the inner wall of the connecting member.
  • the first fitting component is a fitting protrusion and/or a fitting groove.
  • the number of the first pipe breaking component is equal to that of the second pipe breaking component.
  • the number of parts is equal or not equal.
  • the number of the first pipe breaking parts is equal to the number of the second pipe breaking parts, and the number of the first pipe breaking parts is equal to the number of the second pipe breaking parts.
  • a second pipe breaking part is arranged between two adjacent first pipe breaking parts, and a first breaking part is arranged between two adjacent second pipe breaking parts. Pipe parts.
  • the number of the first pipe-breaking component is one, the number of the second pipe-breaking component is two, and the flow guiding component is arranged on the first pipe-breaking component and the second pipe-breaking component. Between the pipes and between the two second broken pipe parts; or
  • first broken pipe parts There are two first broken pipe parts, one second broken pipe part, and the flow guiding part is arranged between the first broken pipe part and the second broken pipe part and the two Between the first broken pipe parts.
  • first pipe-breaking parts there are at least two first pipe-breaking parts, at least two second pipe-breaking parts, and the number of the first pipe-breaking parts is equal to that of the second pipe-breaking parts. Equal number
  • the second pipe breaking part is arranged between two adjacent first pipe breaking parts, and the first pipe breaking part is arranged between two adjacent second pipe breaking parts.
  • the first cutting element includes a first inclined side, and the first inclined side forms a first angle with a horizontal plane;
  • the second cutting element includes a second inclined side, and the second inclined side forms a second included angle with the horizontal plane;
  • the third cutting element includes a third inclined side, and the third inclined side forms a third angle with the horizontal plane;
  • first included angle and the second included angle are equal or unequal
  • first included angle and the third included angle are equal or unequal
  • second included angle is equal to or unequal to the third included angle.
  • the angles vary.
  • the second included angle is smaller than the third included angle.
  • the horizontal width of the first broken pipe component is equal to or different from the horizontal width of the second broken pipe component.
  • the horizontal width of the first broken pipe component is smaller than the horizontal width of the second broken pipe component.
  • the sum of the horizontal width of the first broken pipe component and the horizontal width of the second broken pipe component is less than or equal to the minimum horizontal width of the body.
  • the vertical height of the first pipe breaking component is equal to the vertical height of the second pipe breaking component.
  • the spreading element is a spreading inclined surface or a spreading spherical surface.
  • a biochemical test tube comprising the broken tube structure as described above, and the broken tube structure is arranged at the bottom of the solution chamber of the biochemical test tube.
  • it includes a tube portion and a cover portion
  • the tube includes:
  • a test paper fixing component where the top of the solution chamber communicates with the top of the test paper fixing component when the cover part closes the tube part;
  • a plurality of first positioning parts, the plurality of the first positioning parts are arranged at the bottom of the solution chamber for positioning the broken tube structure;
  • a plurality of second positioning components are provided on the upper part of the plurality of first positioning components.
  • a plurality of the first positioning components surrounds to form a first chamber
  • a plurality of the second positioning components surround to form a second cavity
  • the axis of the first chamber is coaxial with the axis of the second chamber.
  • a plurality of the first positioning components surrounds to form a first chamber
  • a plurality of the second positioning components surround to form a second cavity
  • the horizontal distance between the axis of the first chamber and the axis of the second chamber is less than 3 mm.
  • the biochemical test tube further includes:
  • a sample tube the sample tube is placed in the solution chamber, and is fixed in cooperation with a plurality of the second positioning components, and the bottom of the sample tube is in contact with the tip and/or the blade of the tube breaking structure.
  • the cover includes:
  • a pressing member, the pressing member is arranged inside the cover;
  • the pressing member is aligned with the solution chamber of the tube part.
  • the tube part further includes:
  • a sealing platform is arranged on the end surface of the top of the solution chamber, and the sealing platform is arranged all around the solution chamber;
  • the sealing platform When the cover part closes the tube part, the sealing platform has a certain distance from the bottom of the cover part.
  • the tube part further includes:
  • the sealing film is connected with the sealing platform to seal the solution cavity.
  • the biochemical test tube further includes:
  • Biochemical test paper the biochemical test paper is arranged inside the test paper fixing part;
  • the sample solution receiving end of the biochemical test paper is close to the cover part.
  • the length of the biochemical test paper is greater than the height of the test paper fixing part.
  • the biochemical test tube further includes:
  • a transparent hollow tube, the biochemical test paper is arranged inside the transparent hollow tube, and the transparent hollow tube is arranged inside the test paper fixing member.
  • one end of the transparent hollow tube is a closed end.
  • a thermally conductive blind tube which is applied to the biochemical test tube as described in the second aspect.
  • the thermally conductive blind tube is inserted into the biochemical test tube and is located at the bottom of the biochemical test tube. The broken pipe structure is destroyed.
  • they include:
  • a heat-conducting component is connected to the bottom opening of the blind tube body, and the heat-conducting component seals the bottom opening of the blind tube body;
  • the thermal conductivity of the thermally conductive component ⁇ >1.0 W/(m ⁇ K).
  • the material of the thermally conductive component includes metal.
  • the material of the thermally conductive component includes thermally conductive plastic, and the thermal conductivity of the thermally conductive plastic ⁇ >1.0 W/(m ⁇ K).
  • the heat-conducting component includes a heat-conducting block, and the heat-conducting block is fitted and connected with the blind pipe body.
  • a second fitting part is provided on the heat conducting block.
  • the second inserting component includes a convex ring provided on the heat conducting block and a groove provided on the blind tube body and matingly connected with the convex ring.
  • two convex rings are provided.
  • a blind tube cover is further included, and the blind tube cover and the blind tube body are integrally formed.
  • the present invention adopts the above technical solutions and has the following technical effects:
  • the broken tube structure, the biochemical test tube and the heat-conducting blind tube of the present invention use the broken tube structure to destroy the sample tube in a sealed state, so that the sample solution in the sample tube is mixed with the reaction solution, and subsequent operations and observations are performed , Making the whole detection process a fully enclosed detection, without any risk of exposure or infection; the broken tube structure includes multiple cutting elements and expansion elements, simplifying the steps of destroying the sample tube, and applying less pressure can destroy the sample tube , And make the solution in the sample tube flow out quickly through the guide part to improve the mixing efficiency.
  • Figure 1 is a schematic diagram (1) of the broken pipe structure according to the present application.
  • Figure 2 is a schematic diagram of the broken pipe structure according to the present application (2);
  • Figure 3 is a top view of the broken pipe structure according to the present application (1);
  • Figure 4 is a cross-sectional view (1) of the broken pipe structure according to the present application.
  • Figure 5 is a schematic diagram of the broken pipe structure according to the present application (3).
  • Figure 6 is a schematic diagram of the broken pipe structure according to the present application (4);
  • Figure 7 is a top view of the broken pipe structure according to the present application (2).
  • Figure 8 is a cross-sectional view of the broken pipe structure according to the present application (2).
  • Figure 9 is a schematic diagram of the broken pipe structure according to the present application (5).
  • Figure 10 is a schematic diagram of the broken pipe structure according to the present application (6);
  • Figure 11 is a top view of the broken pipe structure according to the present application (3).
  • Figure 12 is a cross-sectional view of the broken pipe structure according to the present application (3);
  • Figure 13 is a schematic diagram of the broken pipe structure according to the present application (7);
  • Figure 14 is a schematic diagram of the broken pipe structure according to the present application (8);
  • Figure 15 is a top view of the broken pipe structure according to the present application (4);
  • Figure 16 is a cross-sectional view of the broken pipe structure according to the present application (4);
  • Figure 17 is a schematic diagram of the broken pipe structure according to the present application (9).
  • Figure 18 is a bottom view of the broken pipe structure according to the present application.
  • Figure 19 is a cross-sectional view of the broken pipe structure according to the present application (5);
  • Figure 20 is a cross-sectional view of the broken pipe structure according to the present application (6);
  • Figure 21 is a cross-sectional view of the broken pipe structure according to the present application (7);
  • Figure 22 is a cross-sectional view (1) of the biochemical test tube according to the present application.
  • Figure 23 is a schematic diagram (1) of the use process of the biochemical test tube according to the present application.
  • Figure 24 is a schematic diagram (2) of the use process of the biochemical test tube according to the present application.
  • Figure 25 is a cross-sectional view of the biochemical test tube according to the present application (2).
  • Figure 26 is a cross-sectional view of the biochemical test tube according to the present application (3).
  • Figure 27 is a cross-sectional view of the biochemical test tube according to the present application (4);
  • Figure 28 is a cross-sectional view of the biochemical test tube according to the present application (5);
  • Figure 29 is a cross-sectional view of the biochemical test tube according to the present application (6);
  • Figure 30 is a cross-sectional view of the biochemical test tube according to the present application (7);
  • Figure 31 is a cross-sectional view (1) of the biochemical test tube in an unclosed state according to an embodiment of the present application
  • Figure 32 is a cross-sectional view of the closed state of the biochemical test tube according to an embodiment of the application (1);
  • Figures 33A-33B are cross-sectional views of the biochemical test tube in use according to an embodiment of the application (1);
  • Figure 34 is a cross-sectional view (2) of the biochemical test tube in an unclosed state according to an embodiment of the present application
  • 35A-35C are cross-sectional views (2) of the biochemical test tube in use according to an embodiment of the application;
  • Figure 36 is a cross-sectional view of the biochemical test tube in an unclosed state according to an embodiment of the application (3);
  • Figure 37 is a cross-sectional view of the closed state of the biochemical test tube according to an embodiment of the application (3);
  • Figures 38A-38C are cross-sectional views of the biochemical test tube in use according to the embodiment of the application (3);
  • Figure 39 is a cross-sectional view of the biochemical test tube in an unclosed state according to an embodiment of the application (4);
  • Figure 40 is a cross-sectional view of the closed state of the biochemical test tube according to an embodiment of the present application (4);
  • Figure 41 is a schematic diagram (1) of an immunochromatographic test paper according to an embodiment of the present application.
  • Figure 42 is a cross-sectional view of an immunochromatographic test paper according to an embodiment of the present application (2);
  • Figure 43 is a schematic diagram of an immunochromatographic test paper according to an embodiment of the present application (2).
  • Figure 44 is a cross-sectional view of an immunochromatographic test paper according to an embodiment of the present application (2);
  • Fig. 45 is a schematic diagram of an immunochromatographic test paper according to an embodiment of the present application (3);
  • Figure 46 is a cross-sectional view of an immunochromatographic test paper according to an embodiment of the application (3);
  • Figure 47 is a schematic diagram of an immunochromatographic test paper according to an embodiment of the present application (4);
  • Figure 48 is a cross-sectional view of an immunochromatographic test paper according to an embodiment of the present application (4);
  • Figure 49 is a cross-sectional view of an immunochromatographic test paper according to an embodiment of the present application (5);
  • Figure 50 is a cross-sectional view of a transparent hollow tube according to an embodiment of the present application (1);
  • Figure 51 is a cross-sectional view of a transparent hollow tube according to an embodiment of the present application (2);
  • Figure 52 is a cross-sectional view of a biochemical test tube according to an embodiment of the present application (a biochemical test paper with a transparent hollow tube is provided);
  • FIG. 53 is a structural cross-sectional view of a blind heat conducting tube according to an embodiment of the present application.
  • Fig. 54 is a partial enlarged view of a blind heat conduction tube according to an embodiment of the present application.
  • Fig. 55 is a perspective view of the structure of a blind heat conduction tube according to an embodiment of the present application.
  • the reference signs are: 100, broken pipe structure; 110, body; 120, broken pipe part; 121, cutting element; 122, spreading element; 130, flow guiding part; 140, first broken pipe part; 141, The first cutting element; 142, the first spreading element; 150, the second broken tube part; 151, the second cutting element; 152, the third cutting element; 153, the second spreading element; 160, the connecting part; 170, The first fitting part;
  • Biochemical test tube 210, tube part; 211, solution chamber; 212, test paper fixing part; 213, first positioning part; 214, second positioning part; 215, sealing platform; 216, sealing film; 217, second insert Closing part; 220, cover part; 221, cavity; 222, pressing part; 223, sealing part; 224, third fitting part; 230, connecting part;
  • Biochemical test paper 401, basic layer; 402, chromatographic membrane; 403, test line; 404, quality control line; 405, absorbent pad; 406, binding pad; 407, guiding membrane; 408, sample pad; 409, sample Limited film; 410, transparent protective film;
  • a broken pipe structure 100 includes a main body 110, at least two broken pipe parts 120 and at least two flow guiding parts 130. Among them, at least two broken pipe parts 120 are arranged above the main body 110, and two adjacent broken pipe parts 120 are arranged with flow guiding parts 130.
  • the main body 110 is a cylinder or a truncated cone or a chamfered cylinder or a composite formed by superimposing multiple cylinders.
  • the broken pipe component 120 includes a cutting element 121 and a spreading element 122.
  • the cutting element 121 is arranged above the broken tube component 120 and used to cut the bottom of the sample tube;
  • the spreading element 122 is arranged below the cutting element 121 and is respectively connected to the main body 110 and the cutting element 121 for aligning
  • the cutting element 121 cuts the gap formed at the bottom of the sample tube to expand the gap.
  • the cutting element 121 includes an inclined side, the inclined side forms an angle with the horizontal plane, and the included angle is an acute angle.
  • the maximum horizontal width of the cutting element 121 is equal to the minimum horizontal width of the expansion element 122 and is smaller than the maximum horizontal width of the expansion element 122.
  • the vertical height of the cutting element 121 and the vertical height of the spreading element 122 are equal or different.
  • the horizontal width refers to the radial distance centered on a certain point on the horizontal plane, and does not refer to the thickness of related components
  • the vertical height refers to the axial distance centered on a certain point on the horizontal plane, and does not refer to the thickness of related components.
  • the cutting element 121 is a cutting edge.
  • the spreading element 122 is a spreading surface, and the spreading surface can be a spreading inclined surface or a spreading spherical surface.
  • the number of broken pipe parts 120 is at least two, and several broken pipe parts 120 are connected so that the respective cutting elements 121 and expansion elements 122 face outwards, and when viewed from a plan view, a petal-shaped structure is formed.
  • the flow guiding member 130 is arranged between two adjacent pipe breaking parts 120, and is used for the case where the breaking pipe part 120 is inserted into the bottom of the sample tube and destroys the sample tube, so that the sample solution in the sample tube flows along the guiding part 130 toward the sample tube. It flows out from the outside and mixes with the reaction solution or functional solution outside the sample tube for subsequent operations and observations.
  • the number of the guiding parts 130 is at least two, and not less than the number of the broken pipe parts 120.
  • the flow guide member 130 is a flow guide gap or a flow guide groove.
  • the broken tube structure 100 is made of a metal material that meets medical standards, such as 304 stainless steel.
  • the broken tube structure 100 may also be made of hard plastic material.
  • the method of use of the present invention is as follows: the broken tube structure 100 contacts the bottom of the sample tube (the bottom of the sample tube can be flat or curved); the cutting element 121 cuts the bottom of the sample tube so that the cutting element 121 enters the sample The inside of the tube; the expansion element 122 expands the gap formed by the cutting element 121 cutting the sample tube, that is, while the radial length of the gap becomes longer, the width of the gap becomes wider; at this time, under the action of the broken tube component 120 , The bottom of the sample tube is destroyed, and the sample solution in the sample tube flows out of the sample tube along the guide part 130, thereby mixing with the functional reaction solution outside the sample tube.
  • a broken pipe structure 100 includes a main body 110, a plurality of first broken pipe parts 140 and a plurality of flow guiding parts 130.
  • the first pipe breaking part 140 is arranged above the main body 110 and used to break the bottom of the sample tube; the flow guiding part 130 is arranged between two adjacent first pipe breaking parts 140.
  • the structure and connection relationship of the main body 110 and the flow guiding member 130 are basically the same as those of the first embodiment, and will not be repeated here.
  • the first pipe breaking component 140 includes a first cutting element 141 and a first spreading element 142.
  • the first cutting element 141 is arranged above the first broken tube component 140 and is used to cut the bottom of the sample tube;
  • the first spreading element 142 is arranged below the first cutting element 141, and is connected to the main body 110,
  • the first cutting element 141 is connected to expand the gap formed by the first cutting element 141 cutting the bottom of the sample tube to enlarge the gap.
  • the first cutting element 141 includes a first inclined side, the first inclined side and the horizontal plane form a first included angle, and the first included angle is an acute angle.
  • the maximum horizontal width of the first cutting element 141 is equal to the minimum horizontal width of the first expansion element 142 and is smaller than the maximum horizontal width of the first expansion element 142.
  • the vertical height of the first cutting element 141 is equal to or different from the vertical height of the first spreading element 142.
  • the first cutting element 141 is a cutting edge.
  • the first spreading element 142 is a spreading surface, and the spreading surface can be a spreading inclined surface or a spreading spherical surface.
  • the number of the first broken pipe parts 140 is at least two, and several first broken pipe parts 140 are connected so that the respective first cutting elements 141 and the first spreading elements 142 face outwards, when viewed from a top view, forming a petal-shaped structure .
  • the usage method of this embodiment is basically the same as that of Embodiment 1, and will not be repeated here.
  • a broken pipe structure 100 includes a main body 110, a plurality of second broken pipe parts 150, a plurality of flow guiding parts 130 and a connecting part 160.
  • the first broken pipe part 140 is arranged above the main body 110 for breaking the bottom of the sample tube;
  • the flow guiding part 130 is arranged between two adjacent first broken pipe parts 140;
  • the connecting part 160 is arranged inside the main body 110 , Used to fix the broken pipe structure 100 at a specific position of a specific device.
  • the structure and connection relationship of the main body 110 and the flow guiding member 130 are basically the same as those of the first embodiment, and will not be repeated here.
  • the second pipe breaking component 150 includes a second cutting element 151, a third cutting element 152 and a second spreading element 153.
  • the second cutting element 151 is arranged above the second pipe breaking part 150, and is used to cut the bottom of the sample tube for the first time;
  • the third cutting element 152 is arranged below the second cutting element 151 and is connected to the second cutting element 151 The element 151 is connected to cut the bottom of the sample tube for the second time;
  • the second spreading element 153 is arranged below the third cutting element 152 and is connected to the body 110 and the third cutting element 152, respectively, for cutting the third
  • the cutting element 152 cuts the gap formed at the bottom of the sample tube to expand the gap.
  • the second cutting element 151 includes a second inclined side, which forms a second included angle with the horizontal plane, and the second included angle is an acute angle.
  • the third cutting element 152 includes a third inclined side which forms a third included angle with the horizontal plane, and the third included angle is an acute angle.
  • the third included angle is greater than the second included angle.
  • the horizontal width of the second cutting element 151 is equal to the minimum horizontal width of the third cutting element 152 and is smaller than the maximum horizontal width of the third cutting element 152.
  • the vertical height of the second cutting element 151 is smaller than the vertical height of the third cutting element 152.
  • the maximum horizontal width of the third cutting element 152 is equal to the minimum horizontal width of the second expansion element 153 and is smaller than the maximum horizontal width of the second expansion element 153.
  • the vertical height of the third cutting element 152 is not less than the vertical height of the second spreading element 153.
  • the number of the second broken pipe components 150 is at least two, and several second broken pipe components 150 are connected so that the respective second cutting elements 151, third cutting elements 152 and second spreading elements 153 face outwards, as viewed from a top view , Forming a petal-shaped structure.
  • the connecting member 160 is disposed inside the main body 110 and communicates with the outside of the main body 110 to connect the connecting member 160 with the connecting element, so that the broken pipe structure 100 is fixed in a special position.
  • the usage method of this embodiment is basically the same as that of Embodiment 1, and will not be repeated here.
  • a broken pipe structure 100 includes a main body 110, a first broken pipe component 140, a second broken pipe component 150 and a flow guiding component 130.
  • the first broken pipe part 140 is arranged above the main body 110 and used to break the bottom of the sample tube;
  • the second broken pipe part 150 is arranged above the main body 110 and is connected to the first broken pipe part 140 for connecting with the first broken pipe part 140.
  • a broken pipe part 140 destroys the bottom of the sample tube together;
  • the flow guiding part 130 is arranged between the first broken pipe part 140 and the second broken pipe part 150.
  • the first pipe breaking component 140 includes a first cutting element 141 and a first spreading element 142.
  • the first cutting element 141 is arranged above the first pipe breaking component 140, and is used to cut the bottom of the sample tube for the first time;
  • the first expansion element 142 is arranged below the first cutting element 141, and is respectively connected with
  • the main body 110 and the first cutting element 141 are connected to expand the gap formed by the first cutting element 141 cutting the bottom of the sample tube to enlarge the gap.
  • the maximum horizontal width of the first cutting element 141 is equal to the minimum horizontal width of the first expansion element 142 and is smaller than the maximum horizontal width of the first expansion element 142.
  • the vertical height of the first cutting element 141 is smaller than the vertical height of the first spreading element 142.
  • the first cutting element 141 includes a first inclined side, the first inclined side and the horizontal plane form a first included angle, and the first included angle is an acute angle.
  • the second pipe breaking component 150 includes a second cutting element 151, a third cutting element 152 and a second spreading element 153.
  • the second pipe breaking part 150 is connected with the first pipe breaking part 140;
  • the second cutting element 151 is arranged above the second pipe breaking part 150, and is used to cut the bottom of the sample tube for the first time;
  • the third cutting element 152 is arranged under the second cutting element 151 and connected to the second cutting element 151, and is used to cut the bottom of the sample tube for the second time;
  • the second spreading element 153 is arranged under the third cutting element 152 and is connected with The main body 110 and the third cutting element 152 are connected to expand the gap formed by the third cutting element 152 cutting the bottom of the sample tube to enlarge the gap.
  • the second cutting element 151 is connected to the first cutting element 141, and the first spreading element 142 is connected to the third cutting element 152 and the second spreading element 153, respectively.
  • the second cutting element 151 includes a second inclined side, which forms a second included angle with the horizontal plane, and the second included angle is an acute angle.
  • the third cutting element 152 includes a third inclined side which forms a third included angle with the horizontal plane, and the third included angle is an acute angle.
  • the first included angle and the second included angle are equal or different, the first included angle and the third included angle are equal or different, and the second included angle is different from the third included angle.
  • the second included angle is smaller than the third included angle.
  • the horizontal width of the second cutting element 151 is equal to the minimum horizontal width of the third cutting element 152 and is smaller than the maximum horizontal width of the third cutting element 152.
  • the vertical height of the second cutting element 151 is smaller than the vertical height of the third cutting element 152.
  • the maximum horizontal width of the third cutting element 152 is equal to the minimum horizontal width of the second expansion element 153 and is smaller than the maximum horizontal width of the second expansion element 153.
  • the vertical height of the third cutting element 152 is not less than the vertical height of the second spreading element 153.
  • the vertical height of the first cutting element 141 is equal to the vertical height of the second cutting element 151, or the difference between the two is within the range of 0.5 ⁇ 0.1 mm.
  • the maximum horizontal width of the second expansion element 153 is greater than the maximum horizontal width of the first expansion element 142.
  • the sum of the vertical height of the third cutting element 152 and the vertical height of the second expansion element 153 is equal to the vertical height of the first expansion element 142, or the difference between the two is within the range of 0.5 ⁇ 0.1 mm.
  • the horizontal width refers to the radial distance centered on a certain point on the horizontal plane, and does not refer to the thickness of related components
  • the vertical height refers to the axial distance centered on a certain point on the horizontal plane, and does not refer to the thickness of related components.
  • A There are one first broken pipe part 140, and two second broken pipe parts 150.
  • the angle formed between the first broken pipe part 140 and the adjacent second broken pipe part 150 is 120°;
  • first broken pipe parts 140 and one second broken pipe part 150 There are two first broken pipe parts 140 and one second broken pipe part 150.
  • the angle formed between the first broken pipe parts 140 and the adjacent second broken pipe parts 150 is 120°;
  • the number of first broken pipe parts 140 is equal to the number of second broken pipe parts 150, and a first broken pipe part 140 is arranged between two adjacent second broken pipe parts 150, and two adjacent first broken pipe parts A second broken pipe part 150 is arranged between the pipe parts 140. If the number of the first broken pipe parts 140 and the number of the second broken pipe parts 150 are both n, the adjacent first broken pipe parts 140 and the second broken pipe parts The included angle formed between the pipe parts 150 is 360°/2n;
  • first broken pipe parts 140 and the number of second broken pipe parts 150 are not equal, then at least one second broken pipe part 150 is provided between two adjacent first broken pipe parts 140, and two adjacent first broken pipe parts At least one first pipe breaking part 140 is arranged between the two pipe breaking parts 150.
  • the adjacent first pipe breaking parts 140 The included angle formed with the second broken pipe part 150 is 360°/(m+n), or the included angle formed between two adjacent first broken pipe parts 140 is 360°/(m+n)( That is, the number of first broken pipe parts 140 is greater than the number of second broken pipe parts 150), or the angle formed between two adjacent second broken pipe parts 150 is 360°/(m+n) (that is, the second The number of broken pipe parts 150 is greater than the number of first broken pipe parts 140).
  • the flow guiding member 130 is provided between the first broken pipe part 140 and the second broken pipe part 150, and is used to insert the sample tube into the first broken pipe part 140 and the second broken pipe part 150.
  • the sample solution in the sample tube flows out of the sample tube along the guide member 130, and is mixed with the reaction solution or functional solution outside the sample tube for subsequent operations and observations.
  • the flow guiding member 130 is a flow guiding gap or a guiding channel or a guiding cavity.
  • the flow guiding part 130 is arranged between the first broken pipe part 140 and the second broken pipe part 150. And between the two second broken pipe parts 150.
  • the flow guiding part 130 is arranged between the first broken pipe part 140 and the second broken pipe part 150. Between the two first broken pipe parts 140.
  • the flow guiding part 130 is arranged between the first broken pipe part 140 and the second broken pipe part 150 Between the two first broken pipe parts 140, or between the two second broken pipe parts 150.
  • the method of use of the present invention is as follows: the broken tube structure 100 contacts the bottom of the sample tube (the bottom of the sample tube can be a flat bottom or an arc-shaped bottom); Cut so that the first cutting element 141 and the second cutting element 151 enter the inside of the sample tube; the third cutting element 152 continues to cut the sample tube along the gap formed by cutting the sample tube by the second cutting element 151, so that the gap is Enlarging, that is, the radial length of the gap becomes longer, but the width of the gap remains unchanged; while the third cutting element 152 cuts the bottom of the sample tube, the first spreading element 142 cuts the sample tube from the first cutting element 141.
  • the gap is expanded, that is, as the radial length of the gap becomes longer, the width of the gap becomes wider; the second expansion element 153 expands the gap formed by the third cutting element 152 cutting the sample tube, that is, the radial length of the gap As it becomes longer, the width of the gap becomes wider; at this time, under the combined action of the first broken tube component 140 and the second broken tube component 150, the bottom of the sample tube is destroyed, and the sample solution in the sample tube runs along the guide part 130 It flows out to the outside of the sample tube and mixes with the functional reaction solution outside the sample tube.
  • a broken pipe structure 100 includes a main body 110, a first broken pipe part 140, a second broken pipe part 150, and a flow guiding part 130 And the connecting part 160.
  • the first broken pipe part 140 is arranged above the main body 110 and used to break the bottom of the sample tube;
  • the second broken pipe part 150 is arranged above the main body 110 and is connected to the first broken pipe part 140 for connecting with the first broken pipe part 140.
  • a broken pipe part 140 destroys the bottom of the sample tube together; the flow guiding part 130 is arranged between the first broken pipe part 140 and the second broken pipe part 150; the connecting part 160 is arranged inside the main body 110 for connecting the broken pipe structure 100 is fixed at a specific location on a specific device.
  • the structure and embodiments of the main body 110, the first broken pipe part 140, the second broken pipe part 150, and the flow guiding part 130 are basically the same as those of the first embodiment, and will not be repeated here.
  • the connecting member 160 is disposed inside the main body 110 and communicates with the outside of the main body 110 to connect the connecting member 160 with the connecting element, so that the broken pipe structure 100 is fixed in a special position.
  • the advantage of this embodiment is that a connecting part is provided on the body, and the broken tube structure can be fixed at any special position, so as to adapt to test tubes of different specifications and meet different usage requirements.
  • a broken pipe structure 100 includes a main body 110, a first broken pipe part 140, a second broken pipe part 150, and a diversion The component 130, the connecting component 160, and the first fitting component 170.
  • the first broken pipe part 140 is arranged above the main body 110 and used to break the bottom of the sample tube;
  • the second broken pipe part 150 is arranged above the main body 110 and is connected to the first broken pipe part 140 for connecting with the first broken pipe part 140.
  • a broken pipe part 140 destroys the bottom of the sample tube together; the flow guiding part 130 is arranged between the first broken pipe part 140 and the second broken pipe part 150; the connecting part 160 is arranged inside the main body 110 for connecting the broken pipe structure 100 is fixed at a specific position of a specific device; the first fitting member 170 is arranged inside the connecting member 160 and is used for fitting the broken pipe structure 100 with a specific connecting element.
  • the structures and embodiments of the main body 110, the first broken pipe component 140, the second broken pipe component 150, the flow guiding component 130, and the connecting component 160 are basically the same as those of the first embodiment, and will not be repeated here.
  • the first fitting member 170 is an annular fitting groove.
  • the first fitting member 170 is an annular fitting protrusion.
  • the advantage of this embodiment is that the first fitting part is arranged inside the connecting part, which improves the connection strength between the broken pipe structure and any connecting element, and prevents the broken pipe structure from falling off during use.
  • a biochemical test tube 200 includes at least a tube portion. At least a solution cavity 211 is arranged inside, and the broken tube structure 100 is arranged at the bottom of the solution cavity 211.
  • the broken pipe structure 100 may be integrally formed with the pipe portion, or may be bonded to the pipe portion.
  • the method of use of this embodiment is as follows: as shown in Figures 23-24, insert the sample tube 300 into the solution chamber 211 of the biochemical test tube 200 so that the bottom of the sample tube 300 is in contact with the broken tube structure 100; 300 applies downward pressure to cause the broken tube structure 100 to destroy the bottom of the sample tube 300 (see Example 1 for the specific process); after the bottom of the sample tube 300 is broken, the sample solution in the sample tube 300 follows the broken tube structure 100
  • the flow guiding member 130 of ⁇ enters into the solution chamber 211 and mixes with the reaction solution in the solution chamber 211.
  • a biochemical test tube 200 includes at least a tube portion, and at least a solution chamber 211 is provided inside the tube portion. At least one first positioning component 213 is provided. The first positioning component 213 is used to limit the position of the broken pipe structure 100, and the broken pipe structure 100 and the first positioning component 213 are detachably connected.
  • the first positioning member 213 is connected to the inner wall and the bottom wall of the solution chamber 211.
  • first positioning component 213 there is one first positioning component 213.
  • the first positioning component 213 and the inner wall of the solution chamber 211 form a positioning cavity, and the broken tube structure 100 is detachably installed in the positioning cavity.
  • the first positioning member 213 and the inner wall of the solution chamber 211 form an inscribed circle, and the inner diameter of the inscribed circle is equal to the outer diameter of the body 110 of the broken tube structure 100, so that the broken tube structure 100 is fixed in the solution chamber. 211 at the bottom.
  • the plurality of first positioning components 213 form a positioning cavity, and the broken tube structure 100 is detachably installed in the positioning cavity.
  • the plurality of first positioning members 213 form an inscribed circle, the inner diameter of the inscribed circle is equal to the outer diameter of the body 110 of the broken tube structure 100, so that the broken tube structure 100 is fixed to the bottom of the solution chamber 211.
  • the advantage of this embodiment is that the specifications of the broken tube structure set in the biochemical test tube can be selected according to different usage requirements, so as to complete subsequent customized assembly, without additional production molds, and reduce production costs.
  • This embodiment is an illustrative embodiment of a biochemical test tube containing the broken tube structure of Embodiment 3 or Embodiment 5 or Embodiment 6, as shown in FIGS. 27-28, a biochemical test tube 200, which includes at least a tube portion. At least a solution cavity 211 is arranged inside the tube portion, and a first positioning component 213 is arranged at the bottom of the solution cavity 211, and the first positioning component 213 is used to limit the position of the broken tube structure 100.
  • the first positioning component 213 is connected to the bottom wall of the solution chamber 211.
  • the broken tube structure 100 is plug-connected with the first positioning component 213.
  • the first positioning component 213 is further provided with a fitting element for fitting connection with the first fitting component 170.
  • the advantage of this embodiment is that the broken pipe structure and the second positioning component are plug-connected to improve the connection strength and avoid displacement of the broken pipe structure during use.
  • a biochemical test tube 200 includes at least a tube portion, and at least a solution chamber 211 is provided inside the tube portion.
  • a number of first positioning components 213 are provided at the bottom of the 211, wherein the first positioning components 213 are used to limit the position of the broken pipe structure 100.
  • first positioning components 213 are connected to the inner wall and the bottom wall of the solution chamber 211, and one first positioning component 213 is connected to the bottom wall of the solution chamber 211.
  • a first positioning component 213 and the inner wall of the solution chamber 211 form a positioning cavity.
  • the first positioning component 213 is disposed at the position of the central axis of the positioning cavity, and the broken tube structure 100 is detachably installed in the positioning cavity.
  • the first positioning member 213 and the inner wall of the solution chamber 211 form an inscribed circle
  • the axis of the first positioning member 213 is coaxial with the axis of the inscribed circle
  • the inner diameter of the inscribed circle is the same as the body of the broken tube structure 100
  • the outer diameters of 110 are equal, so that the broken tube structure 100 is fixed to the bottom of the solution chamber 211.
  • the remaining first positioning components 213 form a positioning cavity.
  • the above-mentioned first positioning component 213 is disposed at the central axis of the positioning cavity, and the broken tube structure 100 is detachably installed in the positioning cavity.
  • a plurality of first positioning components 213 form an inscribed circle, the axis of the first positioning component 213 is coaxial with the axis of the inscribed circle, and the inner diameter of the inscribed circle is the same as the outer diameter of the body 110 of the broken pipe structure 100. The diameters are equal, so that the broken tube structure 100 is fixed to the bottom of the solution chamber 211.
  • the advantage of this embodiment is that the first positioning component is used to guide and limit the broken tube structure, and to strengthen the connection strength between the broken tube structure and the biochemical test tube.
  • a biochemical test tube 200 includes a tube part 210 and a cover part 220, and the cover part 220 is used to seal the tube part 210.
  • the tube 210 includes a solution chamber 211, a test paper fixing part 212, a number of first positioning parts 213, and a number of second positioning parts 214.
  • the axial direction of the solution chamber 211 is collinear or parallel to the axial direction of the pipe 210, and the solution chamber 211 is used to place a solution, such as a reaction solution.
  • the axial direction of the test paper fixing part 212 is parallel to the axial direction of the solution chamber 211, and the test paper fixing part 212 is used to place the biochemical test paper 400.
  • a number of first positioning components 213 are arranged at the bottom of the solution chamber 211 and surround to form a virtual first chamber for placing the broken tube structure 100.
  • the plurality of second positioning members 214 are arranged on the upper part of the plurality of first positioning members 213 and surround a virtual second chamber for guiding and restricting the position of the sample tube 300 placed in the solution chamber 211.
  • the virtual first chamber refers to a space formed by a plurality of first positioning components 213 with a virtual wall set to present a cavity with one side open.
  • the virtual second chamber refers to a space formed by a plurality of second positioning members 214 with a virtual wall to present a cavity with one side open.
  • the axis of the first chamber is coaxial or parallel to the axis of the second chamber, and is used to align the center (or center) of the bottom of the sample tube 300 with the broken tube structure 100, that is, the axis of the sample tube 300 and the broken tube
  • the axes of the structure 100 are approximately collinear so that the tube breaking structure 100 pierces the sample tube 300.
  • the horizontal distance between the axis of the first chamber and the axis of the second chamber is less than 3 mm.
  • the broken pipe structure 100 and the pipe portion 210 may be an integrated design or a separate design. In the case of a split design, the broken pipe structure 100 is installed in the first chamber, such as by bonding.
  • a number of first positioning components 213 are circumferentially arranged on the outer side of the broken pipe structure 100 with the broken pipe structure 100 as the center. Specifically, the included angle formed by two adjacent first positioning components 213 is 360°/n, where n is the number of first positioning components 213.
  • a number of second positioning members 214 are axially arranged outside the sample tube 300 with the sample tube 300 as the center.
  • the included angle formed by two adjacent second positioning components 214 is 360°/n, where n is the number of second positioning components 214.
  • the second positioning member 214 can block the first positioning member 213, that is, a second positioning member 214 is provided directly above each first positioning member 213; the second positioning member 214 may not
  • the first positioning member 213 is shielded, that is, a second positioning member 214 is arranged obliquely above each first positioning member 213, or, viewed from a top view, there is at least one first positioning member 214 between two adjacent second positioning members 214 Part 213.
  • the number of the first positioning components 213 and the number of the second positioning components 214 may be equal or different.
  • each second positioning member 214 contacting the sample tube 300 is matched with the outer surface of the sample tube 300. That is, the inner surfaces of the plurality of second positioning members 214 form a track, and the track has a guiding function and a limiting function. Under the action of the track, the sample tube 300 moves downward and is fixed in the virtual second chamber.
  • the cover 220 includes a cavity 221, and the cavity 221 is formed by the inner surface of the cover 220 bulging outward.
  • the longitudinal section of the cavity 221 is trapezoidal, circular arc or triangular.
  • the biochemical test tube 200 further includes a connecting portion 230, which is connected to the tube portion 210 and the cover portion 220, respectively.
  • the tube portion 210, the cover portion 220, and the connecting portion 230 may be integrally connected, that is, the biochemical test tube 200 is a one-piece test tube.
  • the connection part 230 may be a connection bar.
  • the tube portion 210, the cover portion 220, and the connecting portion 230 may be connected separately, that is, the biochemical test tube 200 is a split test tube.
  • the connecting part 230 may be a locking ring or a locking bar.
  • the tube part 210 and the cover part 220 are respectively provided with locking holes that cooperate with each other. When the cover part 220 closes the tube part 210, the locking bar sequentially passes through the locking holes of the tube part 210 and the cover part 220 to make The cover 220 and the pipe 210 are locked.
  • the method of use of this embodiment is as follows: as shown in Figures 33A to 33B, the sample to be tested is placed in the sample tube 300 and sealed; the solution cavity 211 is exposed, and the sample tube 300 is placed in the solution cavity 211; in several second positions Under the guiding and limiting effect of the component 214, the bottom of the sample tube 300 is aligned with the broken tube structure 100 provided at the bottom of the solution chamber 211, and is pierced by the broken tube structure 100; under the action of the flow channel 106, the solution chamber 211
  • the reaction solution is mixed with the sample to be tested in the sample tube 300 to obtain a mixed solution; the tube part 210 is sealed with the cap 220; after a certain time of reaction, the tube part 210 is tilted to make the immunochromatographic test paper set in the test paper fixing part 212
  • the sample solution receiving end of the sample solution contacts the mixed solution, and the mixed solution is chromatographed on the immunochromatographic test paper; the test result can be obtained by observing the immunochromatographic test paper
  • a biochemical test tube 200 includes a tube part 210, a cover part 220 and a connecting part 230.
  • the tube part 210 and the cover part 220 are connected by the connecting part 230, and the cover part 220 is used to seal the tube part 210.
  • connection relationship and structure of the cover 220 and the connection 230 are basically the same as those of the embodiment 11, and will not be repeated here.
  • the tube 210 includes a solution chamber 211, a test paper fixing part 212, a number of first positioning parts 213, a number of second positioning parts 214, a sealing platform 215, and a sealing film 216.
  • the solution chamber 211, the test paper fixing part 212, and a number of first positioning parts are basically the same as those of the embodiment 11, and will not be repeated here.
  • a sealing platform 215 is provided on the end surface of the top of the solution chamber 211, and the sealing platform 215 is arranged all around the solution chamber 211.
  • the width of the sealing platform 215 is at least 1 mm; the outer wall of the sealing platform 215 and the inner wall of the pipe 210 have a certain horizontal distance, and at least 0.5 mm; between the bottom wall of the sealing platform 215 and the inner wall of the pipe 210 Have a certain vertical distance, and at least 0.5mm.
  • the top of the sealing platform 215 does not contact the bottom of the pipe 210, that is, there is a certain vertical distance between the top of the sealing platform 215 and the bottom of the pipe 210, and it is at least 1 mm. .
  • the sealing film 216 is connected with the sealing platform 215 to seal the solution cavity 211 and is used to prevent the solution preset in the solution cavity 211 from overflowing.
  • the reaction solution when leaving the factory, the reaction solution can be preset in the solution chamber 211, and then the solution chamber 211 can be sealed with the sealing film 216; The reaction solution is placed inside the solution cavity 211, and finally the solution cavity 211 is sealed with a sealing film 216, and the biochemical test tube 200 is stored for later use.
  • the sealing film 216 can also seal the test paper fixing member 212.
  • the test paper fixing part 212 can be sealed before the biochemical test paper is placed on the test paper fixing part 212, that is, to prevent foreign matter from entering the test paper fixing part 212; the test paper fixing part 212 can also be sealed when the biochemical test paper is placed on the test paper fixing part 212, namely Keep the biochemical test paper free from external substances before it is used.
  • the sealing film 216 may be an aluminum foil film or a plastic packaging film.
  • the sealing film 216 can be assembled with the biochemical test tube 200 during the production process, can also be assembled with the biochemical test tube 200 before the transportation process, or can be assembled with the biochemical test tube 200 before the storage process.
  • the shape of the sealing film 216 is substantially the same as the shape of the cavity at the top of the solution chamber 211, that is, the cross-sectional area of the sealing film 216 is slightly larger than the cross-sectional area of the cavity at the top of the solution cavity 211.
  • an auxiliary tool to break the sealing film 216 such as a tool with a sharp point, a blunt end, and a blade.
  • the shape of the sealing film 216 is different from the shape of the cavity opening at the top of the solution chamber 211, that is, the sealing film 216 includes a sealing part and an extension part.
  • the sealing part seals the solution chamber 211. Part of it is formed in one piece.
  • the shape of the sealing part is basically the same as the shape of the cavity opening at the top of the solution chamber 211.
  • the extension part is in a strip shape and is used to separate the sealing part from the solution chamber 211.
  • the method of use of this embodiment is as follows: as shown in FIGS. 35A to 35C, the sealing film 216 is destroyed or removed, and the sample tube 300 loaded with the sample to be tested is placed into the solution chamber 211, and is guided by a number of second positioning members 214 Under the restriction, the bottom of the sample tube 300 is aligned with the broken tube structure 100 arranged at the bottom of the solution chamber 211, and is pierced by the broken tube structure 100; under the action of the flow channel 106, the reaction solution and the sample in the solution chamber 211
  • the sample to be tested in the tube 300 is mixed to obtain a mixed solution; the tube part 210 is sealed with the cap 220; after a certain time of reaction, the tube part 210 is tilted to receive the sample solution of the immunochromatographic test paper set in the test paper fixing part 212
  • a biochemical test tube 200 includes a tube part 210, a cover part 220, and a connecting part 230.
  • the tube part 210 and the cover part 220 are connected by the connecting part 230. Closed.
  • connection relationship and structure of the connecting portion 230 are basically the same as those of the embodiment 11, and will not be repeated here.
  • the tube 210 includes a solution chamber 211, a test paper fixing part 212, a number of first positioning parts 213, a number of second positioning parts 214, a sealing platform 215, and a sealing film 216.
  • the solution chamber 211, the test paper fixing part 212, and a number of first positioning parts The connection relationship and structure of the component 213, the plurality of second positioning components 214, the sealing platform 215, and the sealing film 216 are basically the same as those of the embodiment 12, and will not be repeated here.
  • the cover 220 includes a cavity 221 and a pressing member 222, wherein the connection relationship and structure of the cavity 221 are basically the same as those of the embodiment 11, and will not be repeated here.
  • the pressing member 222 is provided inside the cavity 221.
  • the pressing member 222 is a strip, which is used to align the pressing member 222 with the top of the sample tube 300 when the lid 220 closes the tube 210, and apply a basic element at the position where the pressing member 222 is in contact with the sample tube 300.
  • the vertical downward pressure causes the sample tube 300 to be quickly pierced by the broken tube structure 100.
  • the pressure intensity per unit area can be increased under the same pressure, and the speed at which the sample tube 300 is pierced by the broken tube structure 100 can be increased.
  • the method of use of this embodiment is as follows: as shown in FIGS. 38A to 38C, destroy or remove the sealing film 216, and place the sample tube 300 loaded with the sample to be tested into the solution chamber 211; use the cap 220 to close the tube 210, Under the guiding and limiting action of several second positioning parts 214, the bottom of the sample tube 300 is aligned with the broken tube structure 100 arranged at the bottom of the solution chamber 211; under the pressing of the pressing part 222, the bottom of the sample tube 300 is broken.
  • the structure 100 is punctured; under the action of the flow channel 106, the reaction solution in the solution chamber 211 is mixed with the sample to be tested in the sample tube 300 to obtain a mixed solution; the tube portion 210 is closed with the cap 220; after a certain period of reaction time, Tilt the tube portion 210 to make the sample solution receiving end of the immunochromatographic test paper arranged in the test paper fixing part 212 contact the mixed solution, and the mixed liquid is chromatographed on the immunochromatographic test paper; the detection can be obtained by observing the immunochromatographic test paper Result: After observing the test result, the biochemical test tube 200 can be directly treated as medical waste without worrying about the leakage of the material in the biochemical test tube 200.
  • a biochemical test tube 200 includes a tube part 210, a cover part 220, and a connecting part 230.
  • the tube part 210 and the cover part 220 are connected by the connecting part 230. Closed.
  • connection relationship and structure of the connecting portion 230 are basically the same as those of the embodiment 11, and will not be repeated here.
  • the tube portion 210 includes a solution chamber 211, a test paper fixing part 212, a number of first positioning parts 213, a number of second positioning parts 214, a sealing film 216 and a second fitting part 217.
  • the solution chamber 211, the test paper fixing part 212, a number of The connection relationship and structure of the first positioning component 213, the plurality of second positioning components 214, and the sealing film 216 are basically the same as those of the embodiment 12, and will not be repeated here.
  • the second fitting parts 217 are arranged on the inner wall of the top of the pipe 210 and are arranged at intervals along the axial direction of the pipe 210.
  • the cover 220 includes a cavity 221, a pressing member 222, a sealing member 223 and a third fitting member 224.
  • the connection relationship and structure of the cavity 221 and the pressing member 222 are basically the same as those in the third embodiment, and will not be repeated here.
  • the sealing member 223 and the third fitting member 224 are spaced apart in the axial direction of the cover 220.
  • the sealing member 223 is located on the lower side of the lid 220
  • the third fitting member 224 is located on the upper side of the sealing member 223.
  • the sealing member 223 seals the tube 210, and the second fitting member 217 is fitted and connected to the third fitting member 224, so that the lid 220 and the tube 210 are tightly connected. Connect to improve the anti-opening performance of the biochemical test tube 200.
  • the sealing member 223 is an annular protrusion whose outer diameter is equal to the inner diameter of the top of the tube 210.
  • the second fitting part 217 is an annular protrusion whose outer diameter is larger than the inner diameter of the top of the tube 210; the third fitting part 224 is an annular groove, which is connected to the second fitting part. 217 works closely together.
  • the sealing component, the second fitting component and the third fitting component of this embodiment the tightness of the connection between the cover part and the pipe part is further improved, and the resistance to separate the cover part and the pipe part is greatly improved, which is effective Prevent leakage of the solution in the biochemical test tube 200, avoid pollution of the environment, and prevent endangering life and health.
  • This embodiment relates to biochemical test papers placed in the biochemical test tubes of Examples 11-14.
  • the biochemical test paper is an immunochromatographic test paper as an example for description.
  • a biochemical test paper 400 includes a base layer 401, a chromatographic membrane 402, an absorbent pad 405, a binding pad 406, and a guiding membrane 407, wherein the guiding membrane 407, the binding pad 406, and the chromatographic membrane 402 and the absorbent pad 405 are arranged on the base layer 401 in sequence.
  • the length of the biochemical test paper 400 is greater than the height of the test paper fixing part 212.
  • the difference between the length of the biochemical test paper 400 and the height of the test paper fixing member 212 is 1 mm to 5 mm, and the preferable difference is 2 mm and 3 mm.
  • the sample solution receiving end of the biochemical test paper 400 extends into the cavity 221 of the lid 220.
  • the base layer 401 is made of plastic, such as self-adhesive plastic.
  • the guiding film 407 is disposed on the upper surface of the base layer 401, that is, the lower surface of the guiding film 407 and the upper surface of the base layer 401 are connected, such as by bonding.
  • the end of the guiding film 407 is in contact with the front end of the bonding pad 406, and the guiding film 407 transfers the solution to the bonding pad 406.
  • the upper surface of the end of the guiding film 407 is in contact with the lower surface of the front end of the bonding pad 406, or the lower surface of the end of the guiding film 407 is in contact with the upper surface of the front end of the bonding pad 406.
  • the guiding film 407 is made of cellulose film.
  • the thickness of the guiding film 407 is less than 0.15 mm.
  • the bonding pad 406 is disposed on the upper surface of the base layer 401, that is, the lower surface of the bonding pad 406 and the upper surface of the base layer 401 are connected, such as by bonding.
  • the end of the bonding pad 406 is in contact with the front end of the chromatography membrane 402, and the bonding pad 406 transfers the solution to the chromatography membrane 402.
  • the upper surface of the end of the bonding pad 406 is in contact with the lower surface of the front end of the chromatography membrane 402, or the lower surface of the end of the bonding pad 406 is in contact with the upper surface of the front end of the chromatography membrane 402.
  • the bonding pad 406 is a colloidal gold pad.
  • the bonding pad 406 is made of glass fiber, polyester film, cellulose filter paper, non-woven fabric and other materials.
  • the solution chromatography speed of the guiding membrane 407 is lower than the solution chromatography speed of the binding pad 406.
  • the chromatographic membrane 402 is arranged at least on the upper surface of the base layer 401, that is, the lower surface of the chromatographic membrane 402 and the upper surface of the base layer 401 are connected, such as by bonding.
  • the end of the chromatographic membrane 402 is in contact with the end of the absorbent pad 405, and the chromatographic membrane 402 transfers the solution to the absorbent pad 405.
  • the chromatographic membrane 402 is further provided with a detection line 403 and a quality control line 404, which are sequentially arranged along the front end to the end of the chromatographic membrane 402.
  • the chromatographic membrane 402 is made of nitrocellulose membrane.
  • the absorbent pad 405 is at least disposed on the lower surface of the base layer 401, that is, the upper surface of the absorbent pad 405 and the lower surface of the base layer 401 are connected, such as by bonding.
  • the end of the absorbent pad 405 is in contact with the end of the chromatography membrane 402.
  • the absorbent pad 405 is absorbent paper.
  • the end of the chromatographic membrane 402 and the end of the absorbent pad 405 are in contact with the end of the base layer 401 and the solution is transferred.
  • the end of the chromatography membrane 402 exceeds the end of the base layer 401 by a certain distance
  • the end of the absorbent pad 405 exceeds the end of the base layer 401 by a certain distance
  • the end of the chromatography membrane 402 and the end of the absorbent pad 405 The ends contact and transfer the solution, that is, the lower surface of the end of the chromatography membrane 402 and the upper surface of the end of the absorbent pad 405 contact and transfer the solution.
  • the chromatographic membrane 402, the base layer 401 and the absorbent pad 405 form a sandwich structure.
  • the chromatography membrane 402 is also disposed on the lower surface of the base layer 401, that is, the end of the chromatography membrane 402 is bent downward at the end of the base layer 401. Specifically, the upper surface of the end of the chromatography membrane 402 is in contact with the upper surface of the end of the absorbent pad 405 and the solution is transferred, or the lower surface of the end of the chromatography membrane 402 and the lower surface of the end of the absorbent pad 405 are in contact and solution transfer.
  • the length of the chromatography membrane 402 located on the upper surface of the base layer 401 is greater than the length of the chromatography membrane 402 located on the lower surface of the base layer 401; or, the length of the chromatography membrane 402 located on the upper surface of the base layer 401 is equal to The length of the chromatography membrane 402 located on the lower surface of the base layer 401; or, the length of the chromatography membrane 402 located on the upper surface of the base layer 401 is less than the length of the chromatography membrane 402 located on the lower surface of the base layer 401.
  • the length of the chromatography membrane 402 located on the upper surface of the base layer 401 is greater than the length of the chromatography membrane 402 located on the lower surface of the base layer 401
  • the absorbent pad 405 is also disposed on the upper surface of the base layer 401, that is, the end of the absorbent pad 405 is bent upward at the end of the base layer 401. Specifically, the upper surface of the end of the absorbent pad 405 is in contact with the upper surface of the end of the chromatography membrane 402 and the solution is transferred, or the lower surface of the end of the absorbent pad 405 and the lower surface of the end of the chromatography membrane 402 are in contact and solution transfer.
  • the length of the absorbent pad 405 located on the upper surface of the base layer 401 is greater than the length of the absorbent pad 405 located on the lower surface of the base layer 401; or, the length of the absorbent pad 405 located on the upper surface of the base layer 401 is equal to the length of the absorbent pad 405 located on the upper surface of the base layer 401 Or, the length of the absorbent pad 405 on the upper surface of the base layer 401 is less than the length of the absorbent pad 405 on the lower surface of the base layer 401.
  • the length of the absorbent pad 405 located on the upper surface of the base layer 401 is smaller than the length of the absorbent pad 405 located on the lower surface of the base layer 401.
  • a thin film is also provided at the end of the chromatography membrane 402 and the end of the absorbent pad 405.
  • the thin film covers the chromatographic membrane 402 and the absorbent pad 405 so that the chromatographic membrane 402 and the absorbent pad 405 are kept in contact.
  • the length of the biochemical test paper 400 is 2 cm to 4 cm, preferably 2.8 cm, 3.0 cm, 3.2 cm, or 3.5 cm.
  • the usage method of this embodiment is as follows: put the biochemical test paper 400 into the test paper fixing part 212 of the biochemical test tube 200, and set the sample solution receiving end of the biochemical test paper 400 upward (ie the guiding film 407); destroy or remove the sealing film 216.
  • the bottom of the sample tube 300 is aligned with the broken tube structure provided at the bottom of the solution chamber 211 100, and punctured by the broken tube structure 100; under the action of the flow channel 106, the reaction solution in the solution chamber 211 is mixed with the sample to be tested in the sample tube 300 to obtain a mixed solution; the tube 210 is closed with the cap 220; After reacting for a certain period of time, tilt the tube 210 to make the guiding film 407 of the biochemical test paper 400 arranged in the test paper fixing part 212 contact the mixed liquid, and the mixed liquid undergoes chromatographic action on the biochemical test paper 400; by observing the biochemical test paper 400, The test results can be obtained; after observing the test results, the biochemical test tube 200 can be directly treated as medical waste, and there is no need to worry about the leakage of the material in the biochemical test tube 200.
  • This embodiment relates to biochemical test papers placed in the biochemical test tubes of Examples 11-14.
  • the biochemical test paper is an immunochromatographic test paper as an example for description.
  • a biochemical test paper 400 includes a base layer 401, a chromatographic membrane 402, an absorbent pad 405, a binding pad 406, a guiding film 407, and a sample pad 408, wherein the sample pad 408 and the guiding film 407 ,
  • the bonding pad 406, the chromatographic membrane 402 and the water absorption pad 405 are arranged on the base layer 401.
  • connection relationship, structure and composition of the base layer 401, the chromatographic membrane 402, the water-absorbing pad 405 and the bonding pad 406 are basically the same as those in Embodiment 15, and will not be repeated here.
  • the sample pad 408 is disposed on the upper surface of the base layer 401, that is, the lower surface of the sample pad 408 and the upper surface of the base layer 401 are connected, such as by bonding.
  • the sample pad 408 is made of glass fiber, polyester film, cellulose filter paper, non-woven fabric and other materials.
  • the end of the sample pad 408 is in contact with the front end of the guiding film 407, and the sample pad 408 transfers the solution to the guiding film 407.
  • the upper surface of the end of the sample pad 408 is in contact with the lower surface of the front end of the guiding film 407, or the lower surface of the end of the sample pad 408 is in contact with the upper surface of the front end of the guiding film 407.
  • the front end of the sample pad 408 is in contact with the end of the guiding film 407, and the guiding film 407 transfers the solution to the sample pad 408.
  • the upper surface of the end of the guiding film 407 is in contact with the lower surface of the front end of the sample pad 408, or the lower surface of the end of the guiding film 407 is in contact with the upper surface of the front end of the sample pad 408.
  • the end of the sample pad 408 is in contact with the front end of the bonding pad 406, and the sample pad 408 transfers the solution to the bonding pad 406.
  • the upper surface of the end of the sample pad 408 is in contact with the lower surface of the front end of the bonding pad 406, or the lower surface of the end of the sample pad 408 is in contact with the upper surface of the front end of the bonding pad 406.
  • the immunochromatographic test paper includes two guiding films 407 respectively arranged on the front and back sides of the sample pad 408, that is, the first guiding film 407
  • the end of the membrane 407 is in contact with the front end of the sample pad 408, and the first guiding membrane 407 transfers the solution to the sample pad 408.
  • the upper surface of the end of the first guiding film 407 is in contact with the lower surface of the front end of the sample pad 408, or the lower surface of the end of the first guiding film 407 is in contact with the upper surface of the front end of the sample pad 408 .
  • the end of the sample pad 408 is in contact with the second guiding film 407, and the sample pad 408 transfers the solution to the second guiding film 407.
  • the upper surface of the end of the sample pad 408 is in contact with the lower surface of the front end of the second guiding film 407, or the lower surface of the end of the sample pad 408 is in contact with the upper surface of the front end of the second guiding film 407.
  • the guiding film 407 when there is only one guiding film 407, the guiding film 407 may be the first guiding film; when there are two guiding films 407, the guiding film 407 close to the chromatographic membrane 402 may be The first guiding membrane, and the guiding membrane 407 away from the chromatographic membrane 402 may be the second guiding membrane.
  • the solution chromatography speed of the sample pad 408 is greater than the solution chromatography speed of the guiding membrane 407.
  • the length of the biochemical test paper 400 is 2 cm to 4 cm, preferably 3.2 cm, 3.5 cm.
  • This embodiment relates to biochemical test papers placed in the biochemical test tubes of Examples 11-14.
  • the biochemical test paper is an immunochromatographic test paper as an example for description.
  • a biochemical test paper 400 includes a base layer 401, a chromatographic membrane 402, an absorbent pad 405, a binding pad 406, a guiding film 407, and a sample limiting film 409.
  • the sample limiting film 409, the guiding film The membrane 407, the bonding pad 406, the chromatographic membrane 402 and the water absorption pad 405 are arranged on the base layer 401 in sequence.
  • connection relationship, structure and composition of the base layer 401, the chromatographic membrane 402, the water-absorbing pad 405, the bonding pad 406 and the guiding membrane 407 are basically the same as those of Embodiment 16, and will not be repeated here.
  • the sample limiting film 409 is disposed on the upper surface of the base layer 401, that is, the lower surface of the sample limiting film 409 is connected to the upper surface of the base layer 401, such as by bonding.
  • the end of the sample limiting film 409 is in contact with the front end of the guiding film 407, and the sample limiting film 409 transfers the solution to the guiding film 407.
  • the upper surface of the end of the sample limiting film 409 is in contact with the lower surface of the leading end of the guiding film 407, or the lower surface of the end of the sample limiting film 409 is in contact with the upper surface of the leading end of the guiding film 407.
  • the liquid absorption saturation volume of the sample limiting membrane 409 is 2-20 ⁇ l, which can absorb a small amount of samples.
  • the sample limit film 409 is made of glass fiber, polyester film, cellulose filter paper and other materials.
  • the length of the biochemical test paper 400 is 2 cm to 4 cm, preferably 3.3 cm, 3.5 cm, 3.7 cm.
  • This embodiment relates to biochemical test papers placed in the biochemical test tubes of Examples 11-14.
  • the biochemical test paper is an immunochromatographic test paper as an example for description.
  • a biochemical test paper 400 includes a base layer 401, a chromatographic membrane 402, an absorbent pad 405, a binding pad 406, a guiding membrane 407, a sample pad 408, and a sample limit film 409, wherein the sample limit film 409, the guiding membrane 407, the sample pad 408, the binding pad 406, the chromatography membrane 402, and the water absorption pad 405 are arranged on the base layer 401.
  • connection relationship, structure and composition of the base layer 401, the chromatographic membrane 402, the absorbent pad 405, the bonding pad 406, the guiding membrane 407 and the sample pad 408 are basically the same as those of the second and third embodiments of Example 16. The same, so I won’t repeat them here.
  • the sample limiting film 409 is disposed on the upper surface of the base layer 401, that is, the lower surface of the sample limiting film 409 is connected to the upper surface of the base layer 401, such as by bonding.
  • the end of the sample limiting film 409 is in contact with the front end of the guiding film 407, and the sample limiting film 409 transfers the solution to the guiding film 407.
  • the upper surface of the end of the sample limiting film 409 is in contact with the lower surface of the leading end of the guiding film 407, or the lower surface of the end of the sample limiting film 409 is in contact with the upper surface of the leading end of the guiding film 407.
  • the liquid absorption saturation volume of the sample limiting membrane 409 is 2-20 ⁇ l, which can absorb a small amount of samples.
  • the sample limit film 409 is made of glass fiber, polyester film, cellulose filter paper and other materials.
  • the length of the biochemical test paper 400 is 2 cm to 4 cm, preferably 3.6 cm or 3.8 cm.
  • This embodiment relates to biochemical test papers placed in the biochemical test tubes of Examples 11-14.
  • the biochemical test paper is an immunochromatographic test paper as an example for description.
  • a biochemical test paper 400 includes a base layer 401, a chromatographic membrane 402, a water absorption pad 405, a bonding pad 406, a guiding film 407, and a transparent protective film 410, wherein the guiding film 407, the bonding pad 406, The chromatographic membrane 402 and the absorbent pad 405 are sequentially arranged on the base layer 401.
  • connection relationship, structure and composition of the base layer 401, the chromatographic membrane 402, the water-absorbing pad 405, the bonding pad 406 and the guiding membrane 407 are basically the same as those of Embodiment 15, and will not be repeated here.
  • the lower surface of the transparent protective film 410 covers at least the bonding pad 406 and the chromatographic film 402.
  • the use of the transparent protective film 410 can prevent the bonding pad 406 and the chromatography membrane 402 from contacting the exogenous aqueous mixture, and improve the accuracy of the detection result of the chromatography test paper.
  • the transparent protective film 410 can also be applied to the immunochromatographic test papers of Examples 16-18.
  • the biochemical test paper 400 further includes a transparent hollow tube 500.
  • the transparent hollow tube 500 wraps the biochemical test paper 400 inside the transparent hollow tube 500, that is, the biochemical test paper 400 is disposed inside the transparent hollow tube 500.
  • the inner surface of the transparent hollow tube 500 is a hydrophobic surface.
  • the first end of the transparent hollow tube 500 is a closed end, and the second end is an open end.
  • the purpose of setting the open end is to facilitate the movement of the biochemical test paper 400 from the opening to the inside of the transparent hollow tube 500.
  • sample solution receiving end of the biochemical test paper 400 is located at the open end of the transparent hollow tube 500.
  • the transparent hollow tube 500 is made of a transparent material, such as plastic or thermoplastic resin, which is convenient for observing the detection or diagnosis result of the biochemical test paper 400.
  • the width of the cross section of the second end of the open end of the transparent hollow tube 500 is larger than the inner diameter of the cross section of the first end of the open end.
  • the width of the cross section of the open end of the transparent hollow tube 500 decreases from the second end of the open end to the first end of the open end.
  • putting the biochemical test paper 400 covered with a transparent hollow tube 500 into the test paper fixing part 212 of the biochemical test tube 200 can prevent the biochemical test paper 400 from directly contacting the inner surface of the test paper fixing part 212 and prevent the test paper fixing part
  • the surface tension of the inner surface of 212 affects the adsorption rate of the biochemical test paper 400.
  • a thermally conductive blind tube 600 includes a blind tube body 610 and a thermally conductive component 620 arranged at the bottom of the blind tube body 610, wherein the blind tube body 610 has openings at both ends; the thermally conductive component 620 is connected to the blind tube body 610.
  • the bottom end of the tube body 610 is open, and the heat-conducting component 620 seals the bottom end of the blind tube body 610; the thermal conductivity of the heat-conducting component 620 is ⁇ >1.0 W/(m ⁇ K).
  • the material of the heat-conducting component 620 may be metal, and when the material of the heat-conducting component 620 is metal, the heat-conducting component 620 is fitted and connected with the blind tube body 610;
  • the material of the heat-conducting component 620 can be a heat-conducting plastic.
  • the material of the blind tube body 610 may be ordinary plastic.
  • the bottom of the blind tube body 610 is directly sealed with the heat conducting component 620, which not only improves the thermal conductivity, but also makes the structure of the blind tube 600 simple, which is convenient for manufacturing and saves costs.
  • the heat-conducting component 620 includes a heat-conducting block 621, and the heat-conducting block 621 is fitted and connected with the blind tube body 610.
  • a fourth fitting part is provided on the heat conducting block 621, where the fourth fitting part includes a convex ring 622 arranged on the heat conducting block 621 and a groove arranged on the blind tube body 610 to be matedly connected with the convex ring 622 611.
  • two convex rings 622 are provided, of which one convex ring 622 is connected to the groove 611, and the other convex ring 622 is attached to the inner wall of the blind tube body 610 to improve the sealing performance.
  • the thermally conductive blind tube 600 further includes a blind tube cover 630, and the blind tube cover 630 and the blind tube body 610 are integrally formed. Specifically, the top of the blind tube cover 630 has a figure-eight-shaped structure, so that the blind tube cover 630 has a certain guiding effect.
  • the thermally conductive blind tube 600 can be placed in the biochemical test tube 200 for convenience. Detection operation.
  • the heat-conducting blind tube 600 enters the inside of the biochemical test tube 200 under the action of several second positioning members 214 of the biochemical test tube 200, and contacts the broken tube structure 100 at the bottom of the biochemical test tube 200, and is broken by the tube structure. 100 destroyed.

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Abstract

A tube-breaking structure (100), a biochemical test tube (200) and a heat-conducting blind tube (600). The tube-breaking structure (100) comprises a main body (110), a tube-breaking component (120) and a flow-guiding component (130). The tube-breaking component (120) comprises a cutting element (121) and a spreading element (122) sequentially arranged from top to bottom. The tube-breaking structure (100) can be used to break a sample tube (300) in a closed state, such that a sample solution in the sample tube (300) is mixed with a reaction solution, after which subsequent operations and observations may be performed, thereby ensuring that the entire test process is completely closed without any risk of exposure or infection. The tube-breaking structure (100) comprises multiple cutting elements (121) and spreading elements (122). The invention simplifies the steps of breaking a sample tube (300), reduces the pressing force required to break the sample tube (300), and enables a solution in the sample tube (300) to be quickly discharged by means of a flow-guiding member (130), thereby improving mixing efficiency.

Description

一种破管结构、生化试管及导热盲管A broken tube structure, biochemical test tube and heat conducting blind tube 技术领域Technical field
本发明涉及生化检测装置技术领域,尤其涉及一种破管结构、生化试管及导热盲管。The invention relates to the technical field of biochemical detection devices, in particular to a broken tube structure, a biochemical test tube and a heat-conducting blind tube.
背景技术Background technique
在进行体外诊断或体外检测时,为了能够快速地获得定性结果,通常会采用层析试纸与试管的组合作为快速诊断工具或快速检测工具。一般而言,进行诊断或检测的样品通常会具有一些危险性,如具有一定的毒性、传染性。使用完毕的试管会被当做医疗废弃物进行处理。When performing in vitro diagnosis or in vitro testing, in order to obtain qualitative results quickly, a combination of chromatography test paper and test tube is usually used as a rapid diagnostic tool or rapid detection tool. Generally speaking, the samples for diagnosis or testing usually have some dangers, such as certain toxicity and infectiousness. The used test tubes will be treated as medical waste.
然而,相关技术中的试管存在一些缺陷。例如,在检测时,需要进行反应溶液配制、取样等操作,耗时耗力。此外,在检测时,待检测样品大都处于暴露状态,容易危害检测人员的健康。如使用咽拭子采集样品进行新型冠状病毒检测,咽拭子会直接暴露于空气中,或者使用密封容器进行暂时性存储;进行检测时,将咽拭子从密封容器中取出放入检测装置以进行检测。在取出咽拭子的过程中,咽拭子的短暂暴露提高了检测人员被感染的风险。However, the test tube in the related art has some defects. For example, in the detection, the preparation of the reaction solution, sampling and other operations are required, which is time-consuming and labor-intensive. In addition, during testing, most of the samples to be tested are exposed, which is likely to endanger the health of the testing personnel. If a throat swab is used to collect samples for new coronavirus testing, the throat swab will be directly exposed to the air, or temporarily stored in a sealed container; when testing, the throat swab is taken out of the sealed container and placed in the testing device. Perform testing. In the process of removing the throat swab, the brief exposure of the throat swab increases the risk of infection of the inspector.
目前,针对相关技术中,存在反应溶液现配现用、待检测样品暴露的情况,导致检测效率低、感染风险高的问题,尚未提出有效的解决方案。At present, in related technologies, there is a situation that the reaction solution is currently used and the sample to be tested is exposed, resulting in low detection efficiency and high risk of infection, and no effective solution has been proposed.
发明内容Summary of the invention
本发明的目的是针对现有技术中的不足,提供一种破管结构、生化试管及导热盲管,以至少解决相关技术中检测效率低、感染风险高的问题。The purpose of the present invention is to provide a broken tube structure, a biochemical test tube, and a heat-conducting blind tube in view of the deficiencies in the prior art, so as to at least solve the problems of low detection efficiency and high infection risk in related technologies.
为实现上述目的,本发明采取的技术方案是:In order to achieve the above objectives, the technical solutions adopted by the present invention are:
本发明的第一个方面,提供一种破管结构,包括:In a first aspect of the present invention, a broken pipe structure is provided, including:
本体;Ontology
至少两破管部件,所述破管部件设置于所述本体的上方,所述破管部件包括:At least two broken pipe parts, the broken pipe parts are arranged above the body, and the broken pipe parts include:
切割元件,所述切割元件设置于所述破管部件的上方;A cutting element, the cutting element is arranged above the broken pipe component;
撑开元件,所述撑开元件设置于所述破管部件的下方,并与所述切割元件连接;Expansion element, the expansion element is arranged below the broken pipe part and connected with the cutting element;
导流部件,在相邻两所述破管部件之间设置所述导流部件。The flow guiding part is arranged between two adjacent broken pipe parts.
在其中的一些实施例中,所述破管部件包括:In some of the embodiments, the broken pipe component includes:
第一破管部件,所述第一破管部件包括:The first pipe breaking component, the first pipe breaking component includes:
第一切割元件,所述第一切割元件设置于所述第一破管部件的上方;A first cutting element, the first cutting element is arranged above the first pipe breaking component;
第一撑开元件,所述第一撑开元件设置于所述第一破管部件的下方,位于所述第一切割元件的下方,并与所述第一切割元件连接;A first expansion element, the first expansion element is arranged below the first pipe breaking component, located below the first cutting element, and connected to the first cutting element;
和/或and / or
第二破管部件,所述第二破管部件包括:The second pipe breaking component, the second pipe breaking component includes:
第二切割元件,所述第二切割元件设置于所述第二破管部件的上方;A second cutting element, the second cutting element is arranged above the second pipe breaking component;
第三切割元件,所述第三切割元件设置于所述第二破管部件的上方,位于所述第二切割元件的下方,并与所述第二切割元件连接;A third cutting element, the third cutting element is arranged above the second pipe breaking component, located below the second cutting element, and connected to the second cutting element;
第二撑开元件,所述第二撑开元件设置于所述第二破管部件的下方,位于所述第三切割元件的下方,并与所述第三切割元件连接。The second expansion element, the second expansion element is arranged under the second pipe breaking component, located under the third cutting element, and connected with the third cutting element.
在其中的一些实施例中,还包括:In some of the embodiments, it further includes:
连接部件,所述连接部件设置于所述本体的内部,并与所述本体的外部连通。The connecting part is arranged inside the main body and communicates with the outside of the main body.
在其中的一些实施例中,所述连接部件的纵截面呈凸形。In some of the embodiments, the longitudinal section of the connecting member is convex.
在其中的一些实施例中,还包括:In some of the embodiments, it further includes:
第一嵌合部件,所述第一嵌合部件设置于所述连接部件的内壁。The first fitting member is provided on the inner wall of the connecting member.
在其中的一些实施例中,所述第一嵌合部件为嵌合凸起和/或嵌合凹槽。In some of the embodiments, the first fitting component is a fitting protrusion and/or a fitting groove.
在其中的一些实施例中,在所述破管部件包括所述第一破管部件以及所述第二破管部件的情况下,所述第一破管部件的数量与所述第二破管部件的数量相等或不相等。In some of the embodiments, in the case where the pipe breaking component includes the first pipe breaking component and the second pipe breaking component, the number of the first pipe breaking component is equal to that of the second pipe breaking component. The number of parts is equal or not equal.
在其中的一些实施例中,在所述第一破管部件的数量与所述第二破管部件的数量相等、且所述第一破管部件的数量与所述第二破管部件的数量均至少为两个的情况下,相邻两所述第一破管部件之间设置一所述第二破管部件、相邻两所述第二破管部件之间设置一所述第一破管部件。In some of the embodiments, the number of the first pipe breaking parts is equal to the number of the second pipe breaking parts, and the number of the first pipe breaking parts is equal to the number of the second pipe breaking parts. In the case where there are at least two, a second pipe breaking part is arranged between two adjacent first pipe breaking parts, and a first breaking part is arranged between two adjacent second pipe breaking parts. Pipe parts.
在其中的一些实施例中,所述第一破管部件为1个,所述第二破管部件为2个,所述导流部件设置于所述第一破管部件与所述第二破管之间以及两所述第二破管部件之间;或In some of the embodiments, the number of the first pipe-breaking component is one, the number of the second pipe-breaking component is two, and the flow guiding component is arranged on the first pipe-breaking component and the second pipe-breaking component. Between the pipes and between the two second broken pipe parts; or
所述第一破管部件为2个,所述第二破管部件为1个,所述导流部件设置于所述第一破管部件与所述第二破管部件之间以及两所述第一破管部件之间。There are two first broken pipe parts, one second broken pipe part, and the flow guiding part is arranged between the first broken pipe part and the second broken pipe part and the two Between the first broken pipe parts.
在其中的一些实施例中,所述第一破管部件至少为2个,所述第二破管部件至少为2个,所述第一破管部件的数量与所述第二破管部件的数量相等;In some of these embodiments, there are at least two first pipe-breaking parts, at least two second pipe-breaking parts, and the number of the first pipe-breaking parts is equal to that of the second pipe-breaking parts. Equal number
其中,相邻两个所述第一破管部件之间设置一所述第二破管部件,相邻两个所述第二破管部 件之间设置一所述第一破管部件。Wherein, the second pipe breaking part is arranged between two adjacent first pipe breaking parts, and the first pipe breaking part is arranged between two adjacent second pipe breaking parts.
在其中的一些实施例中,所述第一切割元件包括第一倾斜边,所述第一倾斜边与水平面形成第一夹角;In some of the embodiments, the first cutting element includes a first inclined side, and the first inclined side forms a first angle with a horizontal plane;
所述第二切割元件包括第二倾斜边,所述第二倾斜边与水平面形成第二夹角;The second cutting element includes a second inclined side, and the second inclined side forms a second included angle with the horizontal plane;
所述第三切割元件包括第三倾斜边,所述第三倾斜边与水平面形成第三夹角;The third cutting element includes a third inclined side, and the third inclined side forms a third angle with the horizontal plane;
其中,所述第一夹角与所述第二夹角相等或不等,所述第一夹角与所述第三夹角相等或不等,所述第二夹角与所述第三夹角不等。Wherein, the first included angle and the second included angle are equal or unequal, the first included angle and the third included angle are equal or unequal, and the second included angle is equal to or unequal to the third included angle. The angles vary.
在其中的一些实施例中,所述第二夹角小于所述第三夹角。In some of the embodiments, the second included angle is smaller than the third included angle.
在其中的一些实施例中,所述第一破管部件的水平宽度与所述第二破管部件的水平宽度相等或不等。In some of these embodiments, the horizontal width of the first broken pipe component is equal to or different from the horizontal width of the second broken pipe component.
在其中的一些实施例中,所述第一破管部件的水平宽度小于所述第二破管部件的水平宽度。In some of these embodiments, the horizontal width of the first broken pipe component is smaller than the horizontal width of the second broken pipe component.
在其中的一些实施例中,所述第一破管部件的水平宽度与所述第二破管部件的水平宽度之和小于等于所述本体的最小水平宽度。In some of these embodiments, the sum of the horizontal width of the first broken pipe component and the horizontal width of the second broken pipe component is less than or equal to the minimum horizontal width of the body.
在其中的一些实施例中,所述第一破管部件的竖直高度等于所述第二破管部件的竖直高度。In some of these embodiments, the vertical height of the first pipe breaking component is equal to the vertical height of the second pipe breaking component.
在其中的一些实施例中,所述撑开元件为撑开斜面或撑开球形面。In some of the embodiments, the spreading element is a spreading inclined surface or a spreading spherical surface.
本发明的第二个方面,提供一种生化试管,包括如上所述的破管结构,所述破管结构设置于所述生化试管的溶液腔的底部。In a second aspect of the present invention, there is provided a biochemical test tube, comprising the broken tube structure as described above, and the broken tube structure is arranged at the bottom of the solution chamber of the biochemical test tube.
在其中的一些实施例中,包括管部和盖部;In some of these embodiments, it includes a tube portion and a cover portion;
所述管部包括:The tube includes:
溶液腔;Solution chamber
试纸固定部件,在所述盖部封闭所述管部的情况下,所述溶液腔的顶部和所述试纸固定部件的顶部连通;A test paper fixing component, where the top of the solution chamber communicates with the top of the test paper fixing component when the cover part closes the tube part;
若干第一定位部件,若干所述第一定位部件设置于所述溶液腔的底部,用于定位所述破管结构;A plurality of first positioning parts, the plurality of the first positioning parts are arranged at the bottom of the solution chamber for positioning the broken tube structure;
若干第二定位部件,若干所述第二定位部件设置于若干所述第一定位部件的上部。A plurality of second positioning components are provided on the upper part of the plurality of first positioning components.
在其中的一些实施例中,若干所述第一定位部件围绕形成第一腔室;In some of these embodiments, a plurality of the first positioning components surrounds to form a first chamber;
若干所述第二定位部件围绕形成第二腔室;A plurality of the second positioning components surround to form a second cavity;
所述第一腔室的轴线与所述第二腔室的轴线共轴。The axis of the first chamber is coaxial with the axis of the second chamber.
在其中的一些实施例中,若干所述第一定位部件围绕形成第一腔室;In some of these embodiments, a plurality of the first positioning components surrounds to form a first chamber;
若干所述第二定位部件围绕形成第二腔室;A plurality of the second positioning components surround to form a second cavity;
所述第一腔室的轴线与所述第二腔室的轴线的之间的水平距离小于3mm。The horizontal distance between the axis of the first chamber and the axis of the second chamber is less than 3 mm.
在其中的一些实施例中,所述生化试管还包括:In some of the embodiments, the biochemical test tube further includes:
样品管,所述样品管放置在所述溶液腔,与若干所述第二定位部件配合固定,所述样品管的底部与所述破管结构的尖端和/或刃部接触。A sample tube, the sample tube is placed in the solution chamber, and is fixed in cooperation with a plurality of the second positioning components, and the bottom of the sample tube is in contact with the tip and/or the blade of the tube breaking structure.
在其中的一些实施例中,所述盖部包括:In some of the embodiments, the cover includes:
按压部件,所述按压部件设置于所述盖部的内部;A pressing member, the pressing member is arranged inside the cover;
其中,在所述盖部封闭所述管部的情况下,所述按压部件对准所述管部的所述溶液腔。Wherein, when the cover part closes the tube part, the pressing member is aligned with the solution chamber of the tube part.
在其中的一些实施例中,所述管部还包括:In some of the embodiments, the tube part further includes:
密封平台,所述密封平台设置在所述溶液腔的顶部的端面,所述密封平台全部地环绕所述溶液腔设置;A sealing platform, the sealing platform is arranged on the end surface of the top of the solution chamber, and the sealing platform is arranged all around the solution chamber;
在所述盖部封闭所述管部的情况下,所述密封平台与所述盖部的底部具有一定距离。When the cover part closes the tube part, the sealing platform has a certain distance from the bottom of the cover part.
在其中的一些实施例中,所述管部还包括:In some of the embodiments, the tube part further includes:
密封膜,所述密封膜与所述密封平台连接以密封所述溶液腔。The sealing film is connected with the sealing platform to seal the solution cavity.
在其中的一些实施例中,所述生化试管还包括:In some of the embodiments, the biochemical test tube further includes:
生化试纸,所述生化试纸设置于所述试纸固定部件的内部;Biochemical test paper, the biochemical test paper is arranged inside the test paper fixing part;
其中,在所述盖部封闭所述管部的情况下,所述生化试纸的样品溶液接收端靠近所述盖部。Wherein, when the cover part closes the tube part, the sample solution receiving end of the biochemical test paper is close to the cover part.
在其中的一些实施例中,所述生化试纸的长度大于所述试纸固定部件的高度。In some of the embodiments, the length of the biochemical test paper is greater than the height of the test paper fixing part.
在其中的一些实施例中,所述生化试管还包括:In some of the embodiments, the biochemical test tube further includes:
透明中空管,所述生化试纸设置于所述透明中空管的内部,所述透明中空管设置于所述试纸固定部件的内部。A transparent hollow tube, the biochemical test paper is arranged inside the transparent hollow tube, and the transparent hollow tube is arranged inside the test paper fixing member.
在其中的一些实施例中,所述透明中空管的一端为封闭端。In some of these embodiments, one end of the transparent hollow tube is a closed end.
本发明的第三个方面,提供一种导热盲管,应用于如第二方面所述的生化试管,所述导热盲管插入所述生化试管,并被位于所述生化试管的底部的所述破管结构破坏。In a third aspect of the present invention, there is provided a thermally conductive blind tube, which is applied to the biochemical test tube as described in the second aspect. The thermally conductive blind tube is inserted into the biochemical test tube and is located at the bottom of the biochemical test tube. The broken pipe structure is destroyed.
在其中的一些实施例中,包括:In some of these embodiments, they include:
盲管体,所述盲管体两端具有开口;A blind tube body with openings at both ends of the blind tube body;
导热部件,所述导热部件连接于所述盲管体底端开口,且所述导热部件将所述盲管体底端开口密封;A heat-conducting component, the heat-conducting component is connected to the bottom opening of the blind tube body, and the heat-conducting component seals the bottom opening of the blind tube body;
其中,所述导热部件的导热系数λ>1.0W/(m·K)。Wherein, the thermal conductivity of the thermally conductive component λ>1.0 W/(m·K).
在其中的一些实施例中,所述导热部件的材料包括金属。In some of the embodiments, the material of the thermally conductive component includes metal.
在其中的一些实施例中,所述导热部件的材料包括导热塑料,且导热塑料的导热系数λ>1.0W/(m·K)。In some of the embodiments, the material of the thermally conductive component includes thermally conductive plastic, and the thermal conductivity of the thermally conductive plastic λ>1.0 W/(m·K).
在其中的一些实施例中,所述导热部件包括导热块,所述导热块与所述盲管体嵌合连接。In some of the embodiments, the heat-conducting component includes a heat-conducting block, and the heat-conducting block is fitted and connected with the blind pipe body.
在其中的一些实施例中,所述导热块上设置有第二嵌合部件。In some of the embodiments, a second fitting part is provided on the heat conducting block.
在其中的一些实施例中,所述第二嵌合部件包括设置于所述导热块上的凸环以及设置于所述盲管体上与所述凸环配合连接的凹槽。In some of the embodiments, the second inserting component includes a convex ring provided on the heat conducting block and a groove provided on the blind tube body and matingly connected with the convex ring.
在其中的一些实施例中,所述凸环设置有两个。In some of these embodiments, two convex rings are provided.
在其中的一些实施例中,还包括盲管盖,所述盲管盖与所述盲管体为一体成型结构。In some of the embodiments, a blind tube cover is further included, and the blind tube cover and the blind tube body are integrally formed.
本发明采用以上技术方案,与现有技术相比,具有如下技术效果:Compared with the prior art, the present invention adopts the above technical solutions and has the following technical effects:
本发明的一种破管结构、生化试管及导热盲管,利用破管结构,可以在密封状态下对样品管进行破坏,使样品管内的样品溶液与反应溶液混合,进而进行后续的操作与观察,使整个检测过程为全封闭式检测,无任何暴露风险、感染风险;破管结构包括多个切割元件以及撑开元件,简化破坏样品管的步骤,施加较少的压力即可将样品管破坏,并使样品管内的溶液通过导流部件快速流出,提高混合效率。The broken tube structure, the biochemical test tube and the heat-conducting blind tube of the present invention use the broken tube structure to destroy the sample tube in a sealed state, so that the sample solution in the sample tube is mixed with the reaction solution, and subsequent operations and observations are performed , Making the whole detection process a fully enclosed detection, without any risk of exposure or infection; the broken tube structure includes multiple cutting elements and expansion elements, simplifying the steps of destroying the sample tube, and applying less pressure can destroy the sample tube , And make the solution in the sample tube flow out quickly through the guide part to improve the mixing efficiency.
附图说明Description of the drawings
图1是根据本申请的破管结构的示意图(一);Figure 1 is a schematic diagram (1) of the broken pipe structure according to the present application;
图2是根据本申请的破管结构的示意图(二);Figure 2 is a schematic diagram of the broken pipe structure according to the present application (2);
图3是根据本申请的破管结构的俯视图(一);Figure 3 is a top view of the broken pipe structure according to the present application (1);
图4是根据本申请的破管结构的剖面图(一);Figure 4 is a cross-sectional view (1) of the broken pipe structure according to the present application;
图5是根据本申请的破管结构的示意图(三);Figure 5 is a schematic diagram of the broken pipe structure according to the present application (3);
图6是根据本申请的破管结构的示意图(四);Figure 6 is a schematic diagram of the broken pipe structure according to the present application (4);
图7是根据本申请的破管结构的俯视图(二);Figure 7 is a top view of the broken pipe structure according to the present application (2);
图8是根据本申请的破管结构的剖面图(二);Figure 8 is a cross-sectional view of the broken pipe structure according to the present application (2);
图9是根据本申请的破管结构的示意图(五);Figure 9 is a schematic diagram of the broken pipe structure according to the present application (5);
图10是根据本申请的破管结构的示意图(六);Figure 10 is a schematic diagram of the broken pipe structure according to the present application (6);
图11是根据本申请的破管结构的俯视图(三);Figure 11 is a top view of the broken pipe structure according to the present application (3);
图12是根据本申请的破管结构的剖面图(三);Figure 12 is a cross-sectional view of the broken pipe structure according to the present application (3);
图13是根据本申请的破管结构的示意图(七);Figure 13 is a schematic diagram of the broken pipe structure according to the present application (7);
图14是根据本申请的破管结构的示意图(八);Figure 14 is a schematic diagram of the broken pipe structure according to the present application (8);
图15是根据本申请的破管结构的俯视图(四);Figure 15 is a top view of the broken pipe structure according to the present application (4);
图16是根据本申请的破管结构的剖面图(四);Figure 16 is a cross-sectional view of the broken pipe structure according to the present application (4);
图17是根据本申请的破管结构的示意图(九);Figure 17 is a schematic diagram of the broken pipe structure according to the present application (9);
图18是根据本申请的破管结构的仰视图;Figure 18 is a bottom view of the broken pipe structure according to the present application;
图19是根据本申请的破管结构的剖面图(五);Figure 19 is a cross-sectional view of the broken pipe structure according to the present application (5);
图20是根据本申请的破管结构的剖面图(六);Figure 20 is a cross-sectional view of the broken pipe structure according to the present application (6);
图21是根据本申请的破管结构的剖面图(七);Figure 21 is a cross-sectional view of the broken pipe structure according to the present application (7);
图22是根据本申请的生化试管的剖面图(一);Figure 22 is a cross-sectional view (1) of the biochemical test tube according to the present application;
图23是根据本申请的生化试管的使用过程的的示意图(一);Figure 23 is a schematic diagram (1) of the use process of the biochemical test tube according to the present application;
图24是根据本申请的生化试管的使用过程的的示意图(二);Figure 24 is a schematic diagram (2) of the use process of the biochemical test tube according to the present application;
图25是根据本申请的生化试管的剖面图(二);Figure 25 is a cross-sectional view of the biochemical test tube according to the present application (2);
图26是根据本申请的生化试管的剖面图(三);Figure 26 is a cross-sectional view of the biochemical test tube according to the present application (3);
图27是根据本申请的生化试管的剖面图(四);Figure 27 is a cross-sectional view of the biochemical test tube according to the present application (4);
图28是根据本申请的生化试管的剖面图(五);Figure 28 is a cross-sectional view of the biochemical test tube according to the present application (5);
图29是根据本申请的生化试管的剖面图(六);Figure 29 is a cross-sectional view of the biochemical test tube according to the present application (6);
图30是根据本申请的生化试管的剖面图(七);Figure 30 is a cross-sectional view of the biochemical test tube according to the present application (7);
图31是根据本申请实施例的生化试管的未封闭状态的剖面图(一);Figure 31 is a cross-sectional view (1) of the biochemical test tube in an unclosed state according to an embodiment of the present application;
图32是根据本申请实施例的生化试管的封闭状态的剖面图(一);Figure 32 is a cross-sectional view of the closed state of the biochemical test tube according to an embodiment of the application (1);
图33A-33B是根据本申请实施例的生化试管的使用状态的剖面图(一);Figures 33A-33B are cross-sectional views of the biochemical test tube in use according to an embodiment of the application (1);
图34是根据本申请实施例的生化试管的未封闭状态的剖面图(二);Figure 34 is a cross-sectional view (2) of the biochemical test tube in an unclosed state according to an embodiment of the present application;
图35A-35C是根据本申请实施例的生化试管的使用状态的剖面图(二);35A-35C are cross-sectional views (2) of the biochemical test tube in use according to an embodiment of the application;
图36是根据本申请实施例的生化试管的未封闭状态的剖面图(三);Figure 36 is a cross-sectional view of the biochemical test tube in an unclosed state according to an embodiment of the application (3);
图37是根据本申请实施例的生化试管的封闭状态的剖面图(三);Figure 37 is a cross-sectional view of the closed state of the biochemical test tube according to an embodiment of the application (3);
图38A-38C根根据本申请实施例的生化试管的使用状态的剖面图(三);Figures 38A-38C are cross-sectional views of the biochemical test tube in use according to the embodiment of the application (3);
图39是根据本申请实施例的生化试管的未封闭状态的剖面图(四);Figure 39 is a cross-sectional view of the biochemical test tube in an unclosed state according to an embodiment of the application (4);
图40是根据本申请实施例的生化试管的封闭状态的剖面图(四);Figure 40 is a cross-sectional view of the closed state of the biochemical test tube according to an embodiment of the present application (4);
图41是根据本申请实施例的免疫层析试纸的示意图(一);Figure 41 is a schematic diagram (1) of an immunochromatographic test paper according to an embodiment of the present application;
图42是根据本申请实施例的免疫层析试纸的剖面图(二);Figure 42 is a cross-sectional view of an immunochromatographic test paper according to an embodiment of the present application (2);
图43是根据本申请实施例的免疫层析试纸的示意图(二);Figure 43 is a schematic diagram of an immunochromatographic test paper according to an embodiment of the present application (2);
图44是根据本申请实施例的免疫层析试纸的剖面图(二);Figure 44 is a cross-sectional view of an immunochromatographic test paper according to an embodiment of the present application (2);
图45是根据本申请实施例的免疫层析试纸的示意图(三);Fig. 45 is a schematic diagram of an immunochromatographic test paper according to an embodiment of the present application (3);
图46是根据本申请实施例的免疫层析试纸的剖面图(三);Figure 46 is a cross-sectional view of an immunochromatographic test paper according to an embodiment of the application (3);
图47是根据本申请实施例的免疫层析试纸的示意图(四);Figure 47 is a schematic diagram of an immunochromatographic test paper according to an embodiment of the present application (4);
图48是根据本申请实施例的免疫层析试纸的剖面图(四);Figure 48 is a cross-sectional view of an immunochromatographic test paper according to an embodiment of the present application (4);
图49是根据本申请实施例的免疫层析试纸的剖面图(五);Figure 49 is a cross-sectional view of an immunochromatographic test paper according to an embodiment of the present application (5);
图50是根据本申请实施例的透明中空管的剖面图(一);Figure 50 is a cross-sectional view of a transparent hollow tube according to an embodiment of the present application (1);
图51是根据本申请实施例的透明中空管的剖面图(二);Figure 51 is a cross-sectional view of a transparent hollow tube according to an embodiment of the present application (2);
图52是根据本申请实施例的生化试管的剖面图(设置有套设透明中空管的生化试纸);Figure 52 is a cross-sectional view of a biochemical test tube according to an embodiment of the present application (a biochemical test paper with a transparent hollow tube is provided);
图53是根据本申请实施例的导热盲管的结构剖视图;FIG. 53 is a structural cross-sectional view of a blind heat conducting tube according to an embodiment of the present application;
图54是根据本申请实施例的导热盲管的局部放大图;Fig. 54 is a partial enlarged view of a blind heat conduction tube according to an embodiment of the present application;
图55是根据本申请实施例的导热盲管的结构立体图。Fig. 55 is a perspective view of the structure of a blind heat conduction tube according to an embodiment of the present application.
其中的附图标记为:100、破管结构;110、本体;120、破管部件;121、切割元件;122、撑开元件;130、导流部件;140、第一破管部件;141、第一切割元件;142、第一撑开元件;150、第二破管部件;151、第二切割元件;152、第三切割元件;153、第二撑开元件;160、连接部件;170、第一嵌合部件;The reference signs are: 100, broken pipe structure; 110, body; 120, broken pipe part; 121, cutting element; 122, spreading element; 130, flow guiding part; 140, first broken pipe part; 141, The first cutting element; 142, the first spreading element; 150, the second broken tube part; 151, the second cutting element; 152, the third cutting element; 153, the second spreading element; 160, the connecting part; 170, The first fitting part;
200、生化试管;210、管部;211、溶液腔;212、试纸固定部件;213、第一定位部件;214、第二定位部件;215、密封平台;216、密封膜;217、第二嵌合部件;220、盖部;221、空腔;222、按压部件;223、密封部件;224、第三嵌合部件;230、连接部;200. Biochemical test tube; 210, tube part; 211, solution chamber; 212, test paper fixing part; 213, first positioning part; 214, second positioning part; 215, sealing platform; 216, sealing film; 217, second insert Closing part; 220, cover part; 221, cavity; 222, pressing part; 223, sealing part; 224, third fitting part; 230, connecting part;
300、样品管;300. Sample tube;
400、生化试纸;401、基层;402、层析膜;403、检测线;404、质控线;405、吸水垫;406、结合垫;407、导引膜;408、样品垫;409、样品限量膜;410、透明保护膜;400. Biochemical test paper; 401, basic layer; 402, chromatographic membrane; 403, test line; 404, quality control line; 405, absorbent pad; 406, binding pad; 407, guiding membrane; 408, sample pad; 409, sample Limited film; 410, transparent protective film;
500、透明中空管;500. Transparent hollow tube;
600、导热盲管;610、盲管体;611、凹槽;620、导热部件;621、导热块;622、凸环;630、盲管盖。600, heat conduction blind pipe; 610, blind pipe body; 611, groove; 620, heat conduction component; 621, heat conduction block; 622, convex ring; 630, blind pipe cover.
具体实施方式detailed description
下面将结合本发明实施例中的附图,对本发明实施例中的技术方案进行清楚、完整地描述,显然,所描述的实施例仅仅是本发明一部分实施例,而不是全部的实施例。基于本发明中的实施例,本领域普通技术人员在没有作出创造性劳动的前提下所获得的所有其他实施例,都属于本发明保护的范围。The technical solutions in the embodiments of the present invention will be clearly and completely described below in conjunction with the accompanying drawings in the embodiments of the present invention. Obviously, the described embodiments are only a part of the embodiments of the present invention, rather than all the embodiments. Based on the embodiments of the present invention, all other embodiments obtained by those of ordinary skill in the art without creative work shall fall within the protection scope of the present invention.
需要说明的是,在不冲突的情况下,本发明中的实施例及实施例中的特征可以相互组合。It should be noted that the embodiments of the present invention and the features in the embodiments can be combined with each other if there is no conflict.
下面结合附图和具体实施例对本发明作进一步说明,但不作为本发明的限定。The present invention will be further described below in conjunction with the drawings and specific embodiments, but it is not a limitation of the present invention.
实施例1Example 1
本发明的一个示意性实施例,如图1~4所示,一种破管结构100,包括本体110、至少两个破管部件120以及至少两个导流部件130。其中,至少两个破管部件120设置于本体110的上方,在相邻两个破管部件120设置导流部件130。An exemplary embodiment of the present invention, as shown in FIGS. 1 to 4, a broken pipe structure 100 includes a main body 110, at least two broken pipe parts 120 and at least two flow guiding parts 130. Among them, at least two broken pipe parts 120 are arranged above the main body 110, and two adjacent broken pipe parts 120 are arranged with flow guiding parts 130.
本体110为圆柱体或圆台体或具有倒角的圆柱体或多圆柱体叠加形成的复合体。The main body 110 is a cylinder or a truncated cone or a chamfered cylinder or a composite formed by superimposing multiple cylinders.
如图3所示,破管部件120包括切割元件121以及撑开元件122。其中,切割元件121设置于破管部件120的上方,用于对样品管的底部进行切割;撑开元件122设置于切割元件121的下方,并分别与本体110、切割元件121连接,用于对切割元件121切割样品管底部形成的缝隙进行撑开,以扩大缝隙。As shown in FIG. 3, the broken pipe component 120 includes a cutting element 121 and a spreading element 122. Among them, the cutting element 121 is arranged above the broken tube component 120 and used to cut the bottom of the sample tube; the spreading element 122 is arranged below the cutting element 121 and is respectively connected to the main body 110 and the cutting element 121 for aligning The cutting element 121 cuts the gap formed at the bottom of the sample tube to expand the gap.
切割元件121包括倾斜边,该倾斜边与水平面形成夹角,该夹角为锐角。The cutting element 121 includes an inclined side, the inclined side forms an angle with the horizontal plane, and the included angle is an acute angle.
切割元件121的最大水平宽度与撑开元件122的最小水平宽度相等,并小于撑开元件122的最大水平宽度。The maximum horizontal width of the cutting element 121 is equal to the minimum horizontal width of the expansion element 122 and is smaller than the maximum horizontal width of the expansion element 122.
切割元件121的竖直高度与撑开元件122的竖直高度相等或不等。The vertical height of the cutting element 121 and the vertical height of the spreading element 122 are equal or different.
在上述实施例中,水平宽度指以水平面某点为中心的径向距离,不指代相关元件的厚度;竖直高度指以水平面某点为中心的轴向距离,不指代相关元件的厚度。In the above embodiments, the horizontal width refers to the radial distance centered on a certain point on the horizontal plane, and does not refer to the thickness of related components; the vertical height refers to the axial distance centered on a certain point on the horizontal plane, and does not refer to the thickness of related components. .
在其中的一些实施例中,切割元件121为切割刃。In some of these embodiments, the cutting element 121 is a cutting edge.
在其中的一些实施例中,撑开元件122为撑开面,该撑开面可以为撑开斜面,也可以为撑开球形面。In some of the embodiments, the spreading element 122 is a spreading surface, and the spreading surface can be a spreading inclined surface or a spreading spherical surface.
破管部件120的数量至少为两个,若干破管部件120连接,使各自的切割元件121以及撑开元件122朝向外侧,从俯视角度观察,形成一花瓣形结构。The number of broken pipe parts 120 is at least two, and several broken pipe parts 120 are connected so that the respective cutting elements 121 and expansion elements 122 face outwards, and when viewed from a plan view, a petal-shaped structure is formed.
导流部件130设置于相邻两破管部件120之间,用于破管部件120插入样品管的底部并破坏样品管的情况下,使样品管内的样品溶液沿导流部件130向样品管的外部流出,与样品管外部的反应溶液或功能性溶液混合,以便进行后续的操作和观察。The flow guiding member 130 is arranged between two adjacent pipe breaking parts 120, and is used for the case where the breaking pipe part 120 is inserted into the bottom of the sample tube and destroys the sample tube, so that the sample solution in the sample tube flows along the guiding part 130 toward the sample tube. It flows out from the outside and mixes with the reaction solution or functional solution outside the sample tube for subsequent operations and observations.
具体地,导流部件130的数量至少为两个,且不小于破管部件120的数量。Specifically, the number of the guiding parts 130 is at least two, and not less than the number of the broken pipe parts 120.
举例来说,若破管部件120为两个,则导流部件130也为两个,两个破管部件120连接后形成两个间隔,在一个间隔中设置一个导流部件130,在另一个间隔中设置另一个导流部件130。For example, if there are two broken pipe parts 120, there are also two flow guiding parts 130. After the two broken pipe parts 120 are connected, two gaps are formed. Another air guiding component 130 is provided in the interval.
在其中的一些实施例中,导流部件130为导流间隙或导流槽。In some of the embodiments, the flow guide member 130 is a flow guide gap or a flow guide groove.
在其中的一些实施例中,破管结构100由符合医疗规范的金属材料制成,如304不锈钢。In some of these embodiments, the broken tube structure 100 is made of a metal material that meets medical standards, such as 304 stainless steel.
在其中的一些实施例中,破管结构100也可以由硬质塑料材料制成。In some of these embodiments, the broken tube structure 100 may also be made of hard plastic material.
本发明的使用方法如下:破管结构100接触样品管的底部(样品管的底部可以平面底、可以是弧形底);切割元件121对样品管的底部进行切割,以使切割元件121进入样品管的内部;撑开元件122对切割元件121切割样品管形成的缝隙进行撑开,即缝隙的径向长度变长的同时,缝隙的宽度变宽;此时,在破管部件120的作用下,样品管的底部被破坏,样品管内的样品溶液沿导流部件130向样品管的外部流出,从而与样品管外部的功能性反应溶液混合。The method of use of the present invention is as follows: the broken tube structure 100 contacts the bottom of the sample tube (the bottom of the sample tube can be flat or curved); the cutting element 121 cuts the bottom of the sample tube so that the cutting element 121 enters the sample The inside of the tube; the expansion element 122 expands the gap formed by the cutting element 121 cutting the sample tube, that is, while the radial length of the gap becomes longer, the width of the gap becomes wider; at this time, under the action of the broken tube component 120 , The bottom of the sample tube is destroyed, and the sample solution in the sample tube flows out of the sample tube along the guide part 130, thereby mixing with the functional reaction solution outside the sample tube.
实施例2Example 2
本发明为实施例1的一个变形实施例,如图5~8所示,一种破管结构100,包括本体110、若干第一破管部件140以及若干导流部件130。其中,第一破管部件140设置于本体110的上方,用于破坏样品管的底部;导流部件130设置于相邻两第一破管部件140之间。The present invention is a modified embodiment of Embodiment 1. As shown in FIGS. 5 to 8, a broken pipe structure 100 includes a main body 110, a plurality of first broken pipe parts 140 and a plurality of flow guiding parts 130. Wherein, the first pipe breaking part 140 is arranged above the main body 110 and used to break the bottom of the sample tube; the flow guiding part 130 is arranged between two adjacent first pipe breaking parts 140.
其中,本体110、导流部件130的结构、连接关系同实施例1基本相同,在此不再赘述。Among them, the structure and connection relationship of the main body 110 and the flow guiding member 130 are basically the same as those of the first embodiment, and will not be repeated here.
如图7所示,第一破管部件140包括第一切割元件141以及第一撑开元件142。其中,第一切割元件141设置于第一破管部件140的上方,用于对样品管的底部进行切割;第一撑开元件142设置于第一切割元件141的下方,并分别与本体110、第一切割元件141连接,用于对第一切割元件141切割样品管底部形成的缝隙进行撑开,以扩大缝隙。As shown in FIG. 7, the first pipe breaking component 140 includes a first cutting element 141 and a first spreading element 142. Wherein, the first cutting element 141 is arranged above the first broken tube component 140 and is used to cut the bottom of the sample tube; the first spreading element 142 is arranged below the first cutting element 141, and is connected to the main body 110, The first cutting element 141 is connected to expand the gap formed by the first cutting element 141 cutting the bottom of the sample tube to enlarge the gap.
第一切割元件141包括第一倾斜边,该第一倾斜边与水平面形成第一夹角,该第一夹角为锐角。The first cutting element 141 includes a first inclined side, the first inclined side and the horizontal plane form a first included angle, and the first included angle is an acute angle.
第一切割元件141的最大水平宽度与第一撑开元件142的最小水平宽度相等,并小于第一撑开元件142的最大水平宽度。The maximum horizontal width of the first cutting element 141 is equal to the minimum horizontal width of the first expansion element 142 and is smaller than the maximum horizontal width of the first expansion element 142.
第一切割元件141的竖直高度与第一撑开元件142的竖直高度相等或不等。The vertical height of the first cutting element 141 is equal to or different from the vertical height of the first spreading element 142.
在其中的一些实施例中,第一切割元件141为切割刃。In some of these embodiments, the first cutting element 141 is a cutting edge.
在其中的一些实施例中,第一撑开元件142为撑开面,该撑开面可以为撑开斜面,也可以为撑开球形面。In some of the embodiments, the first spreading element 142 is a spreading surface, and the spreading surface can be a spreading inclined surface or a spreading spherical surface.
第一破管部件140的数量至少为两个,若干第一破管部件140连接,使各自的第一切割元件 141以及第一撑开元件142朝向外侧,从俯视角度观察,形成一花瓣形结构。The number of the first broken pipe parts 140 is at least two, and several first broken pipe parts 140 are connected so that the respective first cutting elements 141 and the first spreading elements 142 face outwards, when viewed from a top view, forming a petal-shaped structure .
本实施例的使用方法同实施例1基本相同,在此不再赘述。The usage method of this embodiment is basically the same as that of Embodiment 1, and will not be repeated here.
实施例3Example 3
本实施例为实施例1的一个变形实施例,如图9~12所示,一种破管结构100,包括本体110、若干第二破管部件150、若干导流部件130以及连接部件160。其中,第一破管部件140设置于本体110的上方,用于破坏样品管的底部;导流部件130设置于相邻两第一破管部件140之间;连接部件160设置于本体110的内部,用于将破管结构100固定于特定装置的特定位置。This embodiment is a modified embodiment of Embodiment 1. As shown in FIGS. 9 to 12, a broken pipe structure 100 includes a main body 110, a plurality of second broken pipe parts 150, a plurality of flow guiding parts 130 and a connecting part 160. Among them, the first broken pipe part 140 is arranged above the main body 110 for breaking the bottom of the sample tube; the flow guiding part 130 is arranged between two adjacent first broken pipe parts 140; the connecting part 160 is arranged inside the main body 110 , Used to fix the broken pipe structure 100 at a specific position of a specific device.
其中,本体110、导流部件130的结构、连接关系同实施例1基本相同,在此不再赘述。Among them, the structure and connection relationship of the main body 110 and the flow guiding member 130 are basically the same as those of the first embodiment, and will not be repeated here.
如图11所示,第二破管部件150包括第二切割元件151、第三切割元件152以及第二撑开元件153。其中,第二切割元件151设置于第二破管部件150的上方,用于对样品管的底部进行第一次切割;第三切割元件152设置于第二切割元件151的下方并与第二切割元件151连接,用于对样品管的底部进行第二次切割;第二撑开元件153设置于第三切割元件152的下方并分别与本体110、第三切割元件152连接,用于对第三切割元件152切割样品管底部形成的缝隙进行撑开,以扩大缝隙。As shown in FIG. 11, the second pipe breaking component 150 includes a second cutting element 151, a third cutting element 152 and a second spreading element 153. Wherein, the second cutting element 151 is arranged above the second pipe breaking part 150, and is used to cut the bottom of the sample tube for the first time; the third cutting element 152 is arranged below the second cutting element 151 and is connected to the second cutting element 151 The element 151 is connected to cut the bottom of the sample tube for the second time; the second spreading element 153 is arranged below the third cutting element 152 and is connected to the body 110 and the third cutting element 152, respectively, for cutting the third The cutting element 152 cuts the gap formed at the bottom of the sample tube to expand the gap.
第二切割元件151包括第二倾斜边,该第二倾斜边与水平面形成第二夹角,该第二夹角为锐角。The second cutting element 151 includes a second inclined side, which forms a second included angle with the horizontal plane, and the second included angle is an acute angle.
第三切割元件152包括第三倾斜边,该第三倾斜边与水平面形成第三夹角,该第三夹角为锐角。The third cutting element 152 includes a third inclined side which forms a third included angle with the horizontal plane, and the third included angle is an acute angle.
在其中的一些实施例中,第三夹角大于第二夹角。In some of the embodiments, the third included angle is greater than the second included angle.
第二切割元件151的水平宽度与第三切割元件152的最小水平宽度相等,并小于第三切割元件152的最大水平宽度。The horizontal width of the second cutting element 151 is equal to the minimum horizontal width of the third cutting element 152 and is smaller than the maximum horizontal width of the third cutting element 152.
第二切割元件151的竖直高度小于第三切割元件152的竖直高度。The vertical height of the second cutting element 151 is smaller than the vertical height of the third cutting element 152.
第三切割元件152的最大水平宽度与第二撑开元件153的最小水平宽度相等,并小于第二撑开元件153的最大水平宽度。The maximum horizontal width of the third cutting element 152 is equal to the minimum horizontal width of the second expansion element 153 and is smaller than the maximum horizontal width of the second expansion element 153.
第三切割元件152的竖直高度不小于第二撑开元件153的竖直高度。The vertical height of the third cutting element 152 is not less than the vertical height of the second spreading element 153.
第二破管部件150的数量至少为两个,若干第二破管部件150连接,使各自的第二切割元件151、第三切割元件152以及第二撑开元件153朝向外侧,从俯视角度观察,形成一花瓣形结构。The number of the second broken pipe components 150 is at least two, and several second broken pipe components 150 are connected so that the respective second cutting elements 151, third cutting elements 152 and second spreading elements 153 face outwards, as viewed from a top view , Forming a petal-shaped structure.
连接部件160设置于本体110的内部,并与本体110的外部相连通,以将连接部件160与连接元件相连接,以使破管结构100固定于某特殊位置。The connecting member 160 is disposed inside the main body 110 and communicates with the outside of the main body 110 to connect the connecting member 160 with the connecting element, so that the broken pipe structure 100 is fixed in a special position.
本实施例的使用方法同实施例1基本相同,在此不再赘述。The usage method of this embodiment is basically the same as that of Embodiment 1, and will not be repeated here.
实施例4Example 4
本发明为实施例1的变形实施例,如图13~16所示,一种破管结构100,包括本体110、第一破管部件140、第二破管部件150以及导流部件130。其中,第一破管部件140设置于本体110的上方,用于破坏样品管的底部;第二破管部件150设置于本体110的上方,并与第一破管部件140连接,用于与第一破管部件140一同破坏样品管的底部;导流部件130设置于第一破管部件140与第二破管部件150之间。The present invention is a modified embodiment of Embodiment 1. As shown in FIGS. 13 to 16, a broken pipe structure 100 includes a main body 110, a first broken pipe component 140, a second broken pipe component 150 and a flow guiding component 130. Among them, the first broken pipe part 140 is arranged above the main body 110 and used to break the bottom of the sample tube; the second broken pipe part 150 is arranged above the main body 110 and is connected to the first broken pipe part 140 for connecting with the first broken pipe part 140. A broken pipe part 140 destroys the bottom of the sample tube together; the flow guiding part 130 is arranged between the first broken pipe part 140 and the second broken pipe part 150.
如图15所示,第一破管部件140包括第一切割元件141以及第一撑开元件142。其中,第一切割元件141设置于第一破管部件140的上方,用于对样品管的底部进行第一次切割;第一撑开元件142设置于第一切割元件141的下方,并分别与本体110、第一切割元件141连接,用于对第一切割元件141切割样品管底部形成的缝隙进行撑开,以扩大缝隙。As shown in FIG. 15, the first pipe breaking component 140 includes a first cutting element 141 and a first spreading element 142. Wherein, the first cutting element 141 is arranged above the first pipe breaking component 140, and is used to cut the bottom of the sample tube for the first time; the first expansion element 142 is arranged below the first cutting element 141, and is respectively connected with The main body 110 and the first cutting element 141 are connected to expand the gap formed by the first cutting element 141 cutting the bottom of the sample tube to enlarge the gap.
第一切割元件141的最大水平宽度与第一撑开元件142的最小水平宽度相等,并小于第一撑开元件142的最大水平宽度。The maximum horizontal width of the first cutting element 141 is equal to the minimum horizontal width of the first expansion element 142 and is smaller than the maximum horizontal width of the first expansion element 142.
第一切割元件141的竖直高度小于第一撑开元件142的竖直高度。The vertical height of the first cutting element 141 is smaller than the vertical height of the first spreading element 142.
第一切割元件141包括第一倾斜边,该第一倾斜边与水平面形成第一夹角,该第一夹角为锐角。The first cutting element 141 includes a first inclined side, the first inclined side and the horizontal plane form a first included angle, and the first included angle is an acute angle.
如图15所示,第二破管部件150包括第二切割元件151、第三切割元件152以及第二撑开元件153。其中,第二破管部件150与第一破管部件140连接;第二切割元件151设置于第二破管部件150的上方,用于对样品管的底部进行第一次切割;第三切割元件152设置于第二切割元件151的下方并与第二切割元件151连接,用于对样品管的底部进行第二次切割;第二撑开元件153设置于第三切割元件152的下方并分别与本体110、第三切割元件152连接,用于对第三切割元件152切割样品管底部形成的缝隙进行撑开,以扩大缝隙。As shown in FIG. 15, the second pipe breaking component 150 includes a second cutting element 151, a third cutting element 152 and a second spreading element 153. Wherein, the second pipe breaking part 150 is connected with the first pipe breaking part 140; the second cutting element 151 is arranged above the second pipe breaking part 150, and is used to cut the bottom of the sample tube for the first time; and the third cutting element 152 is arranged under the second cutting element 151 and connected to the second cutting element 151, and is used to cut the bottom of the sample tube for the second time; the second spreading element 153 is arranged under the third cutting element 152 and is connected with The main body 110 and the third cutting element 152 are connected to expand the gap formed by the third cutting element 152 cutting the bottom of the sample tube to enlarge the gap.
第二切割元件151与第一切割元件141连接,第一撑开元件142分别与第三切割元件152、第二撑开元件153连接。The second cutting element 151 is connected to the first cutting element 141, and the first spreading element 142 is connected to the third cutting element 152 and the second spreading element 153, respectively.
第二切割元件151包括第二倾斜边,该第二倾斜边与水平面形成第二夹角,该第二夹角为锐角。The second cutting element 151 includes a second inclined side, which forms a second included angle with the horizontal plane, and the second included angle is an acute angle.
第三切割元件152包括第三倾斜边,该第三倾斜边与水平面形成第三夹角,该第三夹角为锐角。The third cutting element 152 includes a third inclined side which forms a third included angle with the horizontal plane, and the third included angle is an acute angle.
在其中的一些实施例中,第一夹角与第二夹角相等或不等,第一夹角与第三夹角相等或不等,第二夹角与第三夹角不等。In some of the embodiments, the first included angle and the second included angle are equal or different, the first included angle and the third included angle are equal or different, and the second included angle is different from the third included angle.
在其中的一些实施例中,第二夹角小于第三夹角。In some of the embodiments, the second included angle is smaller than the third included angle.
第二切割元件151的水平宽度与第三切割元件152的最小水平宽度相等,并小于第三切割元件152的最大水平宽度。The horizontal width of the second cutting element 151 is equal to the minimum horizontal width of the third cutting element 152 and is smaller than the maximum horizontal width of the third cutting element 152.
第二切割元件151的竖直高度小于第三切割元件152的竖直高度。The vertical height of the second cutting element 151 is smaller than the vertical height of the third cutting element 152.
第三切割元件152的最大水平宽度与第二撑开元件153的最小水平宽度相等,并小于第二撑开元件153的最大水平宽度。The maximum horizontal width of the third cutting element 152 is equal to the minimum horizontal width of the second expansion element 153 and is smaller than the maximum horizontal width of the second expansion element 153.
第三切割元件152的竖直高度不小于第二撑开元件153的竖直高度。The vertical height of the third cutting element 152 is not less than the vertical height of the second spreading element 153.
第一切割元件141的竖直高度与第二切割元件151的竖直高度相等,或者,两者的差值在0.5±0.1mm范围内。The vertical height of the first cutting element 141 is equal to the vertical height of the second cutting element 151, or the difference between the two is within the range of 0.5±0.1 mm.
第二撑开元件153的最大水平宽度大于第一撑开元件142的最大水平宽度。The maximum horizontal width of the second expansion element 153 is greater than the maximum horizontal width of the first expansion element 142.
第三切割元件152的竖直高度与第二撑开元件153的竖直高度之和与第一撑开元件142的竖直高度相等,或者,两者的差值在0.5±0.1mm范围内。The sum of the vertical height of the third cutting element 152 and the vertical height of the second expansion element 153 is equal to the vertical height of the first expansion element 142, or the difference between the two is within the range of 0.5±0.1 mm.
在上述实施例中,水平宽度指以水平面某点为中心的径向距离,不指代相关元件的厚度;竖直高度指以水平面某点为中心的轴向距离,不指代相关元件的厚度。In the above embodiments, the horizontal width refers to the radial distance centered on a certain point on the horizontal plane, and does not refer to the thickness of related components; the vertical height refers to the axial distance centered on a certain point on the horizontal plane, and does not refer to the thickness of related components. .
对于第一破管部件140以及第二破管部件150,其数量关系如下:For the first broken pipe component 140 and the second broken pipe component 150, the relationship between the numbers is as follows:
A.第一破管部件140为1个,第二破管部件150为2个,第一破管部件140与相邻的第二破管部件150之间形成的夹角为120°;A. There are one first broken pipe part 140, and two second broken pipe parts 150. The angle formed between the first broken pipe part 140 and the adjacent second broken pipe part 150 is 120°;
B.第一破管部件140为2个,第二破管部件150为1个,第一破管部件140与相邻的第二破管部件150之间形成的夹角为120°;B. There are two first broken pipe parts 140 and one second broken pipe part 150. The angle formed between the first broken pipe parts 140 and the adjacent second broken pipe parts 150 is 120°;
C.第一破管部件140的数量与第二破管部件150的数量相等,且相邻两个第二破管部件150之间设置一第一破管部件140,相邻两个第一破管部件140之间设置一第二破管部件150,若第一破管部件140的数量和第二破管部件150的数量均为n,则相邻的第一破管部件140与第二破管部件150之间形成的夹角为360°/2n;C. The number of first broken pipe parts 140 is equal to the number of second broken pipe parts 150, and a first broken pipe part 140 is arranged between two adjacent second broken pipe parts 150, and two adjacent first broken pipe parts A second broken pipe part 150 is arranged between the pipe parts 140. If the number of the first broken pipe parts 140 and the number of the second broken pipe parts 150 are both n, the adjacent first broken pipe parts 140 and the second broken pipe parts The included angle formed between the pipe parts 150 is 360°/2n;
D.第一破管部件140的数量与第二破管部件150的数量不相等,则相邻两个第一破管部件140之间设置至少一第二破管部件150,相邻两个第二破管部件150之间设置至少一第一破管部件140,若第一破管部件140的数量为m、第二破管部件150的数量为n,则相邻的第一破管部件140与第二破管部件150之间形成的夹角为360°/(m+n),或者相邻的两第一破管部件140之间形成的夹角为360°/(m+n)(即第一破管部件140的数量大于第二破管部件150的数量),或者相邻的两第二破管部件150之间形成的夹角为360°/(m+n)(即第二破管部件150的数量大于第一破管部件140的数量)。D. The number of first broken pipe parts 140 and the number of second broken pipe parts 150 are not equal, then at least one second broken pipe part 150 is provided between two adjacent first broken pipe parts 140, and two adjacent first broken pipe parts At least one first pipe breaking part 140 is arranged between the two pipe breaking parts 150. If the number of the first pipe breaking parts 140 is m and the number of the second pipe breaking parts 150 is n, then the adjacent first pipe breaking parts 140 The included angle formed with the second broken pipe part 150 is 360°/(m+n), or the included angle formed between two adjacent first broken pipe parts 140 is 360°/(m+n)( That is, the number of first broken pipe parts 140 is greater than the number of second broken pipe parts 150), or the angle formed between two adjacent second broken pipe parts 150 is 360°/(m+n) (that is, the second The number of broken pipe parts 150 is greater than the number of first broken pipe parts 140).
如图13~16所示,导流部件130设置于第一破管部件140与第二破管部件150之间,用于在第一破管部件140以及第二破管部件150插入样品管的底部并破坏样品管的情况下,使样品管内的样品溶液沿导流部件130向样品管的外部流出,与样品管外部的反应溶液或功能性溶液混合,以便进行后续的操作和观察。As shown in Figures 13-16, the flow guiding member 130 is provided between the first broken pipe part 140 and the second broken pipe part 150, and is used to insert the sample tube into the first broken pipe part 140 and the second broken pipe part 150. When the bottom of the sample tube is damaged, the sample solution in the sample tube flows out of the sample tube along the guide member 130, and is mixed with the reaction solution or functional solution outside the sample tube for subsequent operations and observations.
在其中的一些实施例中,导流部件130为导流间隙或导流通道或导流腔。In some of the embodiments, the flow guiding member 130 is a flow guiding gap or a guiding channel or a guiding cavity.
在其中的一些实施例中,若第一破管部件140为1个且第二破管部件150为2个,则导流部件130设置于第一破管部件140与第二破管部件150之间、以及设置于两第二破管部件150之间。In some of the embodiments, if the number of first broken pipe parts 140 is one and the number of second broken pipe parts 150 is two, the flow guiding part 130 is arranged between the first broken pipe part 140 and the second broken pipe part 150. And between the two second broken pipe parts 150.
在其中的一些实施例中,若第一破管部件140为2个且第二破管部件150为1个,则导流部件130设置于第一破管部件140与第二破管部件150之间、以及设置于两第一破管部件140之间。In some of the embodiments, if there are two first broken pipe parts 140 and one second broken pipe part 150, the flow guiding part 130 is arranged between the first broken pipe part 140 and the second broken pipe part 150. Between the two first broken pipe parts 140.
在其中的一些实施例中,若第一破管部件140的数量与第二破管部件150的数量不相等,则导流部件130设置于第一破管部件140与第二破管部件150之间、或者设置于两第一破管部件140之间、或者设置于两第二破管部件150之间。In some of the embodiments, if the number of the first broken pipe parts 140 and the number of the second broken pipe parts 150 are not equal, the flow guiding part 130 is arranged between the first broken pipe part 140 and the second broken pipe part 150 Between the two first broken pipe parts 140, or between the two second broken pipe parts 150.
本发明的使用方法如下:破管结构100接触样品管的底部(样品管的底部可以平面底、可以是弧形底);第一切割元件141以及第二切割元件151对样品管的底部进行初次切割,以使第一切割元件141以及第二切割元件151进入样品管的内部;第三切割元件152沿第二切割元件151切割样品管形成的缝隙继续对样品管进行切割,以使该缝隙被扩大,即缝隙的径向长度变长,但缝隙的宽度保持不变;在第三切割元件152切割样品管的底部的同时,第一撑开元件142对第一切割元件141切割样品管形成的缝隙进行撑开,即缝隙的径向长度变长的同时,缝隙的宽度变宽;第二撑开元件153对第三切割元件152切割样品管形成的缝隙进行撑开,即缝隙的径向长度变长的同时,缝隙的宽度变宽;此时,在第一破管部件140以及第二破管部件150的共同作用下,样品管的底部被破坏,样品管内的样品溶液沿导流部件130向样品管的外部流出,从而与样品管外部的功能性反应溶液混合。The method of use of the present invention is as follows: the broken tube structure 100 contacts the bottom of the sample tube (the bottom of the sample tube can be a flat bottom or an arc-shaped bottom); Cut so that the first cutting element 141 and the second cutting element 151 enter the inside of the sample tube; the third cutting element 152 continues to cut the sample tube along the gap formed by cutting the sample tube by the second cutting element 151, so that the gap is Enlarging, that is, the radial length of the gap becomes longer, but the width of the gap remains unchanged; while the third cutting element 152 cuts the bottom of the sample tube, the first spreading element 142 cuts the sample tube from the first cutting element 141. The gap is expanded, that is, as the radial length of the gap becomes longer, the width of the gap becomes wider; the second expansion element 153 expands the gap formed by the third cutting element 152 cutting the sample tube, that is, the radial length of the gap As it becomes longer, the width of the gap becomes wider; at this time, under the combined action of the first broken tube component 140 and the second broken tube component 150, the bottom of the sample tube is destroyed, and the sample solution in the sample tube runs along the guide part 130 It flows out to the outside of the sample tube and mixes with the functional reaction solution outside the sample tube.
实施例5Example 5
本实施例为实施例4的一个变形实施例,如图17~19所示,一种破管结构100,包括本体110、第一破管部件140、第二破管部件150、导流部件130以及连接部件160。其中,第一破管部件140设置于本体110的上方,用于破坏样品管的底部;第二破管部件150设置于本体110的上方,并与第一破管部件140连接,用于与第一破管部件140一同破坏样品管的底部;导流部件130设置于第一破管部件140与第二破管部件150之间;连接部件160设置于本体110的内部,用于将破管结构100固定于特定装置的特定位置。This embodiment is a modified embodiment of embodiment 4. As shown in FIGS. 17-19, a broken pipe structure 100 includes a main body 110, a first broken pipe part 140, a second broken pipe part 150, and a flow guiding part 130 And the connecting part 160. Among them, the first broken pipe part 140 is arranged above the main body 110 and used to break the bottom of the sample tube; the second broken pipe part 150 is arranged above the main body 110 and is connected to the first broken pipe part 140 for connecting with the first broken pipe part 140. A broken pipe part 140 destroys the bottom of the sample tube together; the flow guiding part 130 is arranged between the first broken pipe part 140 and the second broken pipe part 150; the connecting part 160 is arranged inside the main body 110 for connecting the broken pipe structure 100 is fixed at a specific location on a specific device.
其中,本体110、第一破管部件140、第二破管部件150以及导流部件130的结构、实施例同 实施例1基本相同,在此不再赘述。Among them, the structure and embodiments of the main body 110, the first broken pipe part 140, the second broken pipe part 150, and the flow guiding part 130 are basically the same as those of the first embodiment, and will not be repeated here.
连接部件160设置于本体110的内部,并与本体110的外部相连通,以将连接部件160与连接元件相连接,以使破管结构100固定于某特殊位置。The connecting member 160 is disposed inside the main body 110 and communicates with the outside of the main body 110 to connect the connecting member 160 with the connecting element, so that the broken pipe structure 100 is fixed in a special position.
本实施例的优点在于,在本体上设置有连接部件,可以将破管结构固定于任意特殊位置,从而适应不同规格的试管,满足不同使用需求。The advantage of this embodiment is that a connecting part is provided on the body, and the broken tube structure can be fixed at any special position, so as to adapt to test tubes of different specifications and meet different usage requirements.
实施例6Example 6
本实施例为实施例5的一个变形实施例,如图17~18、20所示,一种破管结构100,包括本体110、第一破管部件140、第二破管部件150、导流部件130、连接部件160以及第一嵌合部件170。其中,第一破管部件140设置于本体110的上方,用于破坏样品管的底部;第二破管部件150设置于本体110的上方,并与第一破管部件140连接,用于与第一破管部件140一同破坏样品管的底部;导流部件130设置于第一破管部件140与第二破管部件150之间;连接部件160设置于本体110的内部,用于将破管结构100固定于特定装置的特定位置;第一嵌合部件170设置于连接部件160的内部,用于将破管结构100与特定连接元件进行嵌合。This embodiment is a modified embodiment of embodiment 5. As shown in Figures 17-18 and 20, a broken pipe structure 100 includes a main body 110, a first broken pipe part 140, a second broken pipe part 150, and a diversion The component 130, the connecting component 160, and the first fitting component 170. Among them, the first broken pipe part 140 is arranged above the main body 110 and used to break the bottom of the sample tube; the second broken pipe part 150 is arranged above the main body 110 and is connected to the first broken pipe part 140 for connecting with the first broken pipe part 140. A broken pipe part 140 destroys the bottom of the sample tube together; the flow guiding part 130 is arranged between the first broken pipe part 140 and the second broken pipe part 150; the connecting part 160 is arranged inside the main body 110 for connecting the broken pipe structure 100 is fixed at a specific position of a specific device; the first fitting member 170 is arranged inside the connecting member 160 and is used for fitting the broken pipe structure 100 with a specific connecting element.
其中,本体110、第一破管部件140、第二破管部件150、导流部件130以及连接部件160的结构、实施例同实施例1基本相同,在此不再赘述。The structures and embodiments of the main body 110, the first broken pipe component 140, the second broken pipe component 150, the flow guiding component 130, and the connecting component 160 are basically the same as those of the first embodiment, and will not be repeated here.
在其中的一些实施例中,第一嵌合部件170为环形嵌合凹槽。In some of the embodiments, the first fitting member 170 is an annular fitting groove.
在其中的一些实施例中,如图21所示,第一嵌合部件170为环形嵌合凸起。In some of these embodiments, as shown in FIG. 21, the first fitting member 170 is an annular fitting protrusion.
本实施例的优点在于,在连接部件的内部设置第一嵌合部件,提高破管结构与任意连接元件的连接强度,避免使用过程中破管结构脱落。The advantage of this embodiment is that the first fitting part is arranged inside the connecting part, which improves the connection strength between the broken pipe structure and any connecting element, and prevents the broken pipe structure from falling off during use.
实施例7Example 7
本实施例为含有实施例1或实施例2或实施例4的破管结构的生化试管的示意性实施例,如图22所示,一种生化试管200,至少包括管部,该管部的内部至少设置有溶液腔211,破管结构100设置于溶液腔211的底部。This embodiment is a schematic embodiment of a biochemical test tube containing the broken tube structure of Embodiment 1 or Embodiment 2 or Embodiment 4. As shown in FIG. 22, a biochemical test tube 200 includes at least a tube portion. At least a solution cavity 211 is arranged inside, and the broken tube structure 100 is arranged at the bottom of the solution cavity 211.
在本实施例中,破管结构100可以与管部一体成型,也可以与管部进行粘接连接。In this embodiment, the broken pipe structure 100 may be integrally formed with the pipe portion, or may be bonded to the pipe portion.
本实施例的使用方法如下:如图23~24所示,将样品管300插入至生化试管200的溶液腔211的内部,使样品管300的底部与破管结构100相接触;然后对样品管300施加向下的压力,使破管结构100对样品管300的底部进行破坏(具体过程参见实施例1);样品管300的底部被破坏后,样品管300内的样品溶液沿破管结构100的导流部件130进入溶液腔211内,并与溶液腔211内的反应溶液混合。The method of use of this embodiment is as follows: as shown in Figures 23-24, insert the sample tube 300 into the solution chamber 211 of the biochemical test tube 200 so that the bottom of the sample tube 300 is in contact with the broken tube structure 100; 300 applies downward pressure to cause the broken tube structure 100 to destroy the bottom of the sample tube 300 (see Example 1 for the specific process); after the bottom of the sample tube 300 is broken, the sample solution in the sample tube 300 follows the broken tube structure 100 The flow guiding member 130 of φ enters into the solution chamber 211 and mixes with the reaction solution in the solution chamber 211.
实施例8Example 8
本实施例为实施例7的一个变形实施例,如图25~26所示,一种生化试管200,至少包括管部,该管部的内部至少设置有溶液腔211,在溶液腔211的底部设置有至少一第一定位部件213,第一定位部件213用于对破管结构100的位置进行限定,破管结构100与第一定位部件213进行可拆卸连接。This embodiment is a modified embodiment of embodiment 7. As shown in FIGS. 25 to 26, a biochemical test tube 200 includes at least a tube portion, and at least a solution chamber 211 is provided inside the tube portion. At least one first positioning component 213 is provided. The first positioning component 213 is used to limit the position of the broken pipe structure 100, and the broken pipe structure 100 and the first positioning component 213 are detachably connected.
其中,第一定位部件213与溶液腔211的内壁以及底壁连接。Wherein, the first positioning member 213 is connected to the inner wall and the bottom wall of the solution chamber 211.
在其中的一些实施例中,第一定位部件213为1个,该第一定位部件213与溶液腔211的内壁形成定位腔,破管结构100可拆卸地安装于该定位腔内。具体地,第一定位部件213与溶液腔211的内壁形成一内切圆,该内切圆的内径与破管结构100的本体110的外径相等,从而使破管结构100被固定于溶液腔211的底部。In some of the embodiments, there is one first positioning component 213. The first positioning component 213 and the inner wall of the solution chamber 211 form a positioning cavity, and the broken tube structure 100 is detachably installed in the positioning cavity. Specifically, the first positioning member 213 and the inner wall of the solution chamber 211 form an inscribed circle, and the inner diameter of the inscribed circle is equal to the outer diameter of the body 110 of the broken tube structure 100, so that the broken tube structure 100 is fixed in the solution chamber. 211 at the bottom.
在其中的一些实施例中,第一定位部件213为若干个,若干第一定位部件213形成定位腔,破管结构100可拆卸地安装于该定位腔内。具体地,若干第一定位部件213形成一内切圆,该内切圆的内径与破管结构100的本体110的外径相等,从而使破管结构100被固定于溶液腔211的底部。In some of the embodiments, there are a plurality of first positioning components 213, and the plurality of first positioning components 213 form a positioning cavity, and the broken tube structure 100 is detachably installed in the positioning cavity. Specifically, the plurality of first positioning members 213 form an inscribed circle, the inner diameter of the inscribed circle is equal to the outer diameter of the body 110 of the broken tube structure 100, so that the broken tube structure 100 is fixed to the bottom of the solution chamber 211.
本实施例的优点在于,可以根据不同的使用需求,对设置于生化试管内的破管结构的规格进行选择,从而完成后续定制化装配,无须额外开设生产模具,降低生产成本。The advantage of this embodiment is that the specifications of the broken tube structure set in the biochemical test tube can be selected according to different usage requirements, so as to complete subsequent customized assembly, without additional production molds, and reduce production costs.
实施例9Example 9
本实施例为含有实施例3或实施例5或实施例6的的破管结构的生化试管的示意性实施例,如图27~28所示,一种生化试管200,至少包括管部,该管部的内部至少设置有溶液腔211,在溶液腔211的底部设置有第一定位部件213,第一定位部件213用于对破管结构100的位置进行限定。This embodiment is an illustrative embodiment of a biochemical test tube containing the broken tube structure of Embodiment 3 or Embodiment 5 or Embodiment 6, as shown in FIGS. 27-28, a biochemical test tube 200, which includes at least a tube portion. At least a solution cavity 211 is arranged inside the tube portion, and a first positioning component 213 is arranged at the bottom of the solution cavity 211, and the first positioning component 213 is used to limit the position of the broken tube structure 100.
其中,第一定位部件213与溶液腔211的底壁连接。Wherein, the first positioning component 213 is connected to the bottom wall of the solution chamber 211.
破管结构100与第一定位部件213进行插接连接。The broken tube structure 100 is plug-connected with the first positioning component 213.
在其中的一些实施例中,第一定位部件213还设置有与第一嵌合部件170进行嵌合连接的嵌合元件。In some of the embodiments, the first positioning component 213 is further provided with a fitting element for fitting connection with the first fitting component 170.
本实施例的优点在于,将破管结构与第二定位部件进行插接连接,提高连接强度,避免在使用过程中破管结构出现位移。The advantage of this embodiment is that the broken pipe structure and the second positioning component are plug-connected to improve the connection strength and avoid displacement of the broken pipe structure during use.
实施例10Example 10
本实施例为实施例8与实施例9的结合实施例,如图29~30所示,一种生化试管200,至少包括管部,该管部的内部至少设置有溶液腔211,在溶液腔211的底部设置有若干第一定位部件213,其中,第一定位部件213用于对破管结构100的位置进行限定。This embodiment is a combination of embodiment 8 and embodiment 9. As shown in Figs. 29-30, a biochemical test tube 200 includes at least a tube portion, and at least a solution chamber 211 is provided inside the tube portion. A number of first positioning components 213 are provided at the bottom of the 211, wherein the first positioning components 213 are used to limit the position of the broken pipe structure 100.
其中,若干第一定位部件213与溶液腔211的内壁以及底壁连接,一第一定位部件213与溶液腔211的底壁连接。Among them, a number of first positioning components 213 are connected to the inner wall and the bottom wall of the solution chamber 211, and one first positioning component 213 is connected to the bottom wall of the solution chamber 211.
一第一定位部件213与溶液腔211的内壁形成定位腔,第一定位部件213设置于定位腔的中轴位置,破管结构100可拆卸地安装于该定位腔内。具体地,第一定位部件213与溶液腔211的内壁形成一内切圆,第一定位部件213的轴线与该内切圆的轴线共轴,该内切圆的内径与破管结构100的本体110的外径相等,从而使破管结构100被固定于溶液腔211的底部。A first positioning component 213 and the inner wall of the solution chamber 211 form a positioning cavity. The first positioning component 213 is disposed at the position of the central axis of the positioning cavity, and the broken tube structure 100 is detachably installed in the positioning cavity. Specifically, the first positioning member 213 and the inner wall of the solution chamber 211 form an inscribed circle, the axis of the first positioning member 213 is coaxial with the axis of the inscribed circle, and the inner diameter of the inscribed circle is the same as the body of the broken tube structure 100 The outer diameters of 110 are equal, so that the broken tube structure 100 is fixed to the bottom of the solution chamber 211.
其余第一定位部件213形成定位腔,上述一第一定位部件213设置于定位腔的中轴位置,破管结构100可拆卸地安装于该定位腔内。具体地,若干第一定位部件213形成一内切圆,上述一第一定位部件213的轴线与该内切圆的轴线共轴,该内切圆的内径与破管结构100的本体110的外径相等,从而使破管结构100被固定于溶液腔211的底部。The remaining first positioning components 213 form a positioning cavity. The above-mentioned first positioning component 213 is disposed at the central axis of the positioning cavity, and the broken tube structure 100 is detachably installed in the positioning cavity. Specifically, a plurality of first positioning components 213 form an inscribed circle, the axis of the first positioning component 213 is coaxial with the axis of the inscribed circle, and the inner diameter of the inscribed circle is the same as the outer diameter of the body 110 of the broken pipe structure 100. The diameters are equal, so that the broken tube structure 100 is fixed to the bottom of the solution chamber 211.
本实施例的优点在于,第一定位部件用于对破管结构进行导向作用以及限位作用,以及用于加强破管结构与生化试管的连接强度。The advantage of this embodiment is that the first positioning component is used to guide and limit the broken tube structure, and to strengthen the connection strength between the broken tube structure and the biochemical test tube.
实施例11Example 11
如图31~32所示,一种生化试管200,包括管部210和盖部220,盖部220用于对管部210进行封闭。As shown in FIGS. 31 to 32, a biochemical test tube 200 includes a tube part 210 and a cover part 220, and the cover part 220 is used to seal the tube part 210.
管部210包括溶液腔211、试纸固定部件212、若干第一定位部件213、若干第二定位部件214。溶液腔211的轴向与管部210的轴向共线或平行,溶液腔211用于放置溶液,如反应溶液。试纸固定部件212的轴向与溶液腔211的轴向平行,试纸固定部件212用于放置生化试纸400。若干第一定位部件213设置于溶液腔211的底部,并围绕形成虚拟的第一腔室,用于放置破管结构100。若干第二定位部件214设置于若干第一定位部件213的上部,并围绕形成虚拟的第二腔室,用于对放置于溶液腔211内的样品管300进行导向及位置限定。The tube 210 includes a solution chamber 211, a test paper fixing part 212, a number of first positioning parts 213, and a number of second positioning parts 214. The axial direction of the solution chamber 211 is collinear or parallel to the axial direction of the pipe 210, and the solution chamber 211 is used to place a solution, such as a reaction solution. The axial direction of the test paper fixing part 212 is parallel to the axial direction of the solution chamber 211, and the test paper fixing part 212 is used to place the biochemical test paper 400. A number of first positioning components 213 are arranged at the bottom of the solution chamber 211 and surround to form a virtual first chamber for placing the broken tube structure 100. The plurality of second positioning members 214 are arranged on the upper part of the plurality of first positioning members 213 and surround a virtual second chamber for guiding and restricting the position of the sample tube 300 placed in the solution chamber 211.
其中,虚拟的第一腔室是指在若干第一定位部件213形成的空间设置虚拟的墙以呈现一个一面开口的腔。Among them, the virtual first chamber refers to a space formed by a plurality of first positioning components 213 with a virtual wall set to present a cavity with one side open.
同样地,虚拟的第二腔室是指在若干第二定位部件214形成的空间设置虚拟的墙以呈现一个一面开口的腔。Similarly, the virtual second chamber refers to a space formed by a plurality of second positioning members 214 with a virtual wall to present a cavity with one side open.
其中,第一腔室的轴线与第二腔室的轴线共轴或平行,用于使样品管300的底部的中央(或中心)对准破管结构100,即样品管300的轴线与破管结构100的轴线大致共线,以便破管结构100刺破样品管300。Wherein, the axis of the first chamber is coaxial or parallel to the axis of the second chamber, and is used to align the center (or center) of the bottom of the sample tube 300 with the broken tube structure 100, that is, the axis of the sample tube 300 and the broken tube The axes of the structure 100 are approximately collinear so that the tube breaking structure 100 pierces the sample tube 300.
在第一腔室的轴线与第二腔室的轴线平行的情况下,第一腔室的轴线与第二腔室的轴线之间 的水平距离小于3mm。In the case where the axis of the first chamber is parallel to the axis of the second chamber, the horizontal distance between the axis of the first chamber and the axis of the second chamber is less than 3 mm.
破管结构100与管部210可以是一体式设计,也可以是分体式设计。在分体式设计的情况下,破管结构100安装于第一腔室内,如通过粘接等方式进行安装。The broken pipe structure 100 and the pipe portion 210 may be an integrated design or a separate design. In the case of a split design, the broken pipe structure 100 is installed in the first chamber, such as by bonding.
若干第一定位部件213以破管结构100为中心周向设置在破管结构100的外侧。具体地,相邻两个第一定位部件213形成的夹角为360°/n,其中,n为第一定位部件213的数量。A number of first positioning components 213 are circumferentially arranged on the outer side of the broken pipe structure 100 with the broken pipe structure 100 as the center. Specifically, the included angle formed by two adjacent first positioning components 213 is 360°/n, where n is the number of first positioning components 213.
同样地,在样品管300插入第二腔室的情况下,若干第二定位部件214以样品管300为中心轴向设置在样品管300的外侧。具体地,相邻两个第二定位部件214形成的夹角为360°/n,其中,n为第二定位部件214的数量。Similarly, when the sample tube 300 is inserted into the second chamber, a number of second positioning members 214 are axially arranged outside the sample tube 300 with the sample tube 300 as the center. Specifically, the included angle formed by two adjacent second positioning components 214 is 360°/n, where n is the number of second positioning components 214.
此外,以俯视视角观察管部210,第二定位部件214可以遮挡第一定位部件213,即每个第一定位部件213的正上方设置一个第二定位部件214;第二定位部件214也可以不遮挡第一定位部件213,即每个第一定位部件213的斜上方设置一个第二定位部件214,或者,从俯视视角观察,相邻两个第二定位部件214之间至少有一个第一定位部件213。In addition, viewing the tube 210 from a top-view perspective, the second positioning member 214 can block the first positioning member 213, that is, a second positioning member 214 is provided directly above each first positioning member 213; the second positioning member 214 may not The first positioning member 213 is shielded, that is, a second positioning member 214 is arranged obliquely above each first positioning member 213, or, viewed from a top view, there is at least one first positioning member 214 between two adjacent second positioning members 214 Part 213.
其中,第一定位部件213的数量与第二定位部件214的数量可以相等,也可以不等。Wherein, the number of the first positioning components 213 and the number of the second positioning components 214 may be equal or different.
每个第二定位部件214的与样品管300接触的内表面与样品管300的外表面相配合。即,若干第二定位部件214的内表面形成轨道,该轨道具有导向功能和限位功能。在轨道的作用下,样品管300向下移动并固定于虚拟的第二腔室内。The inner surface of each second positioning member 214 contacting the sample tube 300 is matched with the outer surface of the sample tube 300. That is, the inner surfaces of the plurality of second positioning members 214 form a track, and the track has a guiding function and a limiting function. Under the action of the track, the sample tube 300 moves downward and is fixed in the virtual second chamber.
盖部220包括空腔221,空腔221由盖部220的内表面向外凸起形成。The cover 220 includes a cavity 221, and the cavity 221 is formed by the inner surface of the cover 220 bulging outward.
其中,空腔221的纵截面为梯形、圆弧形或三角形。Wherein, the longitudinal section of the cavity 221 is trapezoidal, circular arc or triangular.
此外,生化试管200还包括连接部230,连接部230分别与管部210、盖部220连接。In addition, the biochemical test tube 200 further includes a connecting portion 230, which is connected to the tube portion 210 and the cover portion 220, respectively.
其中,管部210、盖部220和连接部230可以是一体式连接,即生化试管200为连体式试管。在这种情况下,连接部230可以是连接条。Wherein, the tube portion 210, the cover portion 220, and the connecting portion 230 may be integrally connected, that is, the biochemical test tube 200 is a one-piece test tube. In this case, the connection part 230 may be a connection bar.
其中,管部210、盖部220和连接部230可以是分体式连接,即生化试管200为分体式试管。在这种情况下,连接部230可以是锁定环、锁定条。具体地,管部210和盖部220均分别设置有相互配合的锁定孔,在盖部220封闭管部210的情况下,锁定条依次穿过管部210和盖部220的锁定孔,以使盖部220和管部210锁定。Wherein, the tube portion 210, the cover portion 220, and the connecting portion 230 may be connected separately, that is, the biochemical test tube 200 is a split test tube. In this case, the connecting part 230 may be a locking ring or a locking bar. Specifically, the tube part 210 and the cover part 220 are respectively provided with locking holes that cooperate with each other. When the cover part 220 closes the tube part 210, the locking bar sequentially passes through the locking holes of the tube part 210 and the cover part 220 to make The cover 220 and the pipe 210 are locked.
本实施例的使用方法如下:如图33A~33B所示,将待检测样品置入样品管300内并密封;露出溶液腔211,将样品管300放置入溶液腔211内;在若干第二定位部件214的导向限位作用下,样品管300的底部对准设置于溶液腔211底部的破管结构100,并被破管结构100刺破;在流动通道106的作用下,溶液腔211内的反应溶液与样品管300内的待检测样品混合,得到混合液; 用盖部220封闭管部210;待反应一定时间后,倾斜管部210,使设置于试纸固定部件212内的免疫层析试纸的样品溶液接收端接触混合液,混合液在免疫层析试纸上进行层析作用;通过观察免疫层析试纸即可获知检测结果;在观察到检测结果之后,可以直接将生化试管200当做医疗废弃物处理,无须担忧生化试管200内的物质泄漏。The method of use of this embodiment is as follows: as shown in Figures 33A to 33B, the sample to be tested is placed in the sample tube 300 and sealed; the solution cavity 211 is exposed, and the sample tube 300 is placed in the solution cavity 211; in several second positions Under the guiding and limiting effect of the component 214, the bottom of the sample tube 300 is aligned with the broken tube structure 100 provided at the bottom of the solution chamber 211, and is pierced by the broken tube structure 100; under the action of the flow channel 106, the solution chamber 211 The reaction solution is mixed with the sample to be tested in the sample tube 300 to obtain a mixed solution; the tube part 210 is sealed with the cap 220; after a certain time of reaction, the tube part 210 is tilted to make the immunochromatographic test paper set in the test paper fixing part 212 The sample solution receiving end of the sample solution contacts the mixed solution, and the mixed solution is chromatographed on the immunochromatographic test paper; the test result can be obtained by observing the immunochromatographic test paper; after the test result is observed, the biochemical test tube 200 can be directly regarded as a medical waste There is no need to worry about the leakage of the material in the biochemical test tube 200.
实施例12Example 12
如图34所示,一种生化试管200,包括管部210、盖部220和连接部230,管部210和盖部220通过连接部230连接,盖部220用于对管部210进行封闭。As shown in FIG. 34, a biochemical test tube 200 includes a tube part 210, a cover part 220 and a connecting part 230. The tube part 210 and the cover part 220 are connected by the connecting part 230, and the cover part 220 is used to seal the tube part 210.
其中,盖部220和连接部230的连接关系、结构同实施例11基本相同,在此不再赘述。Wherein, the connection relationship and structure of the cover 220 and the connection 230 are basically the same as those of the embodiment 11, and will not be repeated here.
管部210包括溶液腔211、试纸固定部件212、若干第一定位部件213、若干第二定位部件214、密封平台215和密封膜216,其中,溶液腔211、试纸固定部件212、若干第一定位部件213、若干第二定位部件214的连接关系和结构同实施例11基本相同,在此不再赘述。The tube 210 includes a solution chamber 211, a test paper fixing part 212, a number of first positioning parts 213, a number of second positioning parts 214, a sealing platform 215, and a sealing film 216. Among them, the solution chamber 211, the test paper fixing part 212, and a number of first positioning parts The connection relationship and structure of the component 213 and the plurality of second positioning components 214 are basically the same as those of the embodiment 11, and will not be repeated here.
在溶液腔211的顶部的端面设置密封平台215,密封平台215全部地环绕溶液腔211设置。A sealing platform 215 is provided on the end surface of the top of the solution chamber 211, and the sealing platform 215 is arranged all around the solution chamber 211.
其中,密封平台215的宽度至少为1mm;密封平台215的外壁与管部210的内壁之间具有一定的水平距离,且至少为0.5mm;密封平台215的底壁与管部210的内壁之间具有一定的垂直距离,且至少为0.5mm。Among them, the width of the sealing platform 215 is at least 1 mm; the outer wall of the sealing platform 215 and the inner wall of the pipe 210 have a certain horizontal distance, and at least 0.5 mm; between the bottom wall of the sealing platform 215 and the inner wall of the pipe 210 Have a certain vertical distance, and at least 0.5mm.
在盖部220封闭管部210的情况下,密封平台215的顶部与管部210的底部不接触,即密封平台215的顶部与管部210的底部之间具有一定的垂直距离,且至少为1mm。When the cover 220 closes the pipe 210, the top of the sealing platform 215 does not contact the bottom of the pipe 210, that is, there is a certain vertical distance between the top of the sealing platform 215 and the bottom of the pipe 210, and it is at least 1 mm. .
密封膜216与密封平台215连接以密封溶液腔211,用于防止预置在溶液腔211内部的溶液溢出。The sealing film 216 is connected with the sealing platform 215 to seal the solution cavity 211 and is used to prevent the solution preset in the solution cavity 211 from overflowing.
其中,在出厂的时候,可以在溶液腔211内预置反应溶液,然后使用密封膜216对溶液腔211进行密封;或者,出厂后,检测人员拿到生化试管200后,配置反应溶液,并将反应溶液放置到溶液腔211的内部,最后使用密封膜216密封溶液腔211,将生化试管200储存后备用。Among them, when leaving the factory, the reaction solution can be preset in the solution chamber 211, and then the solution chamber 211 can be sealed with the sealing film 216; The reaction solution is placed inside the solution cavity 211, and finally the solution cavity 211 is sealed with a sealing film 216, and the biochemical test tube 200 is stored for later use.
此外,在一些实施例中,密封膜216还可以密封试纸固定部件212。具体地,可以在生化试纸放置在试纸固定部件212之前对试纸固定部件212密封,即避免异物进入试纸固定部件212;也可以在生化试纸放置在试纸固定部件212时候对试纸固定部件212密封,即在未使用前保持生化试纸不受外界物质影响。In addition, in some embodiments, the sealing film 216 can also seal the test paper fixing member 212. Specifically, the test paper fixing part 212 can be sealed before the biochemical test paper is placed on the test paper fixing part 212, that is, to prevent foreign matter from entering the test paper fixing part 212; the test paper fixing part 212 can also be sealed when the biochemical test paper is placed on the test paper fixing part 212, namely Keep the biochemical test paper free from external substances before it is used.
其中,密封膜216可以是铝箔膜,可以是塑封膜。密封膜216可以在生产过程中与生化试管200进行装配,也可以在运输过程前与生化试管200进行装配,也可以在储存过程前与生化试管200进行装配。Wherein, the sealing film 216 may be an aluminum foil film or a plastic packaging film. The sealing film 216 can be assembled with the biochemical test tube 200 during the production process, can also be assembled with the biochemical test tube 200 before the transportation process, or can be assembled with the biochemical test tube 200 before the storage process.
此外,密封膜216的形状与溶液腔211的顶部的腔口的形状基本相同,即密封膜216的横截面的面积略大于溶液腔211的顶部的腔口的横截面的面积。在这种情况下,需要借助辅助工具破坏密封膜216,如具有尖端、钝端、刃部的工具。In addition, the shape of the sealing film 216 is substantially the same as the shape of the cavity at the top of the solution chamber 211, that is, the cross-sectional area of the sealing film 216 is slightly larger than the cross-sectional area of the cavity at the top of the solution cavity 211. In this case, it is necessary to use an auxiliary tool to break the sealing film 216, such as a tool with a sharp point, a blunt end, and a blade.
此外,密封膜216的形状与溶液腔211的顶部的腔口的形状不同,即密封膜216包括密封部分和延伸部分,密封部分密封溶液腔211,延伸部分设置在密封部分的侧部并与密封部分一体成型。其中,密封部分的形状与溶液腔211的顶部的腔口的形状基本相同。延伸部分呈条状,用于使密封部分与溶液腔211分离。In addition, the shape of the sealing film 216 is different from the shape of the cavity opening at the top of the solution chamber 211, that is, the sealing film 216 includes a sealing part and an extension part. The sealing part seals the solution chamber 211. Part of it is formed in one piece. Wherein, the shape of the sealing part is basically the same as the shape of the cavity opening at the top of the solution chamber 211. The extension part is in a strip shape and is used to separate the sealing part from the solution chamber 211.
本实施例的使用方法如下:如图35A~35C所示,破坏或移除密封膜216,将装载有待检测样品的样品管300置入溶液腔211的内部,在若干第二定位部件214的导向限位作用下,样品管300的底部对准设置于溶液腔211底部的破管结构100,并被破管结构100刺破;在流动通道106的作用下,溶液腔211内的反应溶液与样品管300内的待检测样品混合,得到混合液;用盖部220封闭管部210;待反应一定时间后,倾斜管部210,使设置于试纸固定部件212内的免疫层析试纸的样品溶液接收端接触混合液,混合液在免疫层析试纸上进行层析作用;通过观察免疫层析试纸即可获知检测结果;在观察到检测结果之后,可以直接将生化试管200当做医疗废弃物处理,无须担忧生化试管200内的物质泄漏。The method of use of this embodiment is as follows: as shown in FIGS. 35A to 35C, the sealing film 216 is destroyed or removed, and the sample tube 300 loaded with the sample to be tested is placed into the solution chamber 211, and is guided by a number of second positioning members 214 Under the restriction, the bottom of the sample tube 300 is aligned with the broken tube structure 100 arranged at the bottom of the solution chamber 211, and is pierced by the broken tube structure 100; under the action of the flow channel 106, the reaction solution and the sample in the solution chamber 211 The sample to be tested in the tube 300 is mixed to obtain a mixed solution; the tube part 210 is sealed with the cap 220; after a certain time of reaction, the tube part 210 is tilted to receive the sample solution of the immunochromatographic test paper set in the test paper fixing part 212 The end contacts the mixed solution, and the mixed solution is chromatographed on the immunochromatographic test paper; the test result can be obtained by observing the immunochromatographic test paper; after the test result is observed, the biochemical test tube 200 can be directly treated as medical waste without There is a concern that the substance in the biochemical test tube 200 leaks.
实施例13Example 13
如图36~37所示,一种生化试管200,包括管部210、盖部220和连接部230,管部210和盖部220通过连接部230连接,盖部220用于对管部210进行封闭。As shown in Figures 36 to 37, a biochemical test tube 200 includes a tube part 210, a cover part 220, and a connecting part 230. The tube part 210 and the cover part 220 are connected by the connecting part 230. Closed.
其中,连接部230的连接关系、结构同实施例11基本相同,在此不再赘述。Wherein, the connection relationship and structure of the connecting portion 230 are basically the same as those of the embodiment 11, and will not be repeated here.
管部210包括溶液腔211、试纸固定部件212、若干第一定位部件213、若干第二定位部件214、密封平台215和密封膜216,其中,溶液腔211、试纸固定部件212、若干第一定位部件213、若干第二定位部件214、密封平台215和密封膜216的连接关系和结构同实施例12基本相同,在此不再赘述。The tube 210 includes a solution chamber 211, a test paper fixing part 212, a number of first positioning parts 213, a number of second positioning parts 214, a sealing platform 215, and a sealing film 216. Among them, the solution chamber 211, the test paper fixing part 212, and a number of first positioning parts The connection relationship and structure of the component 213, the plurality of second positioning components 214, the sealing platform 215, and the sealing film 216 are basically the same as those of the embodiment 12, and will not be repeated here.
盖部220包括空腔221和按压部件222,其中,空腔221的连接关系、结构同实施例11基本相同,在此不再赘述。The cover 220 includes a cavity 221 and a pressing member 222, wherein the connection relationship and structure of the cavity 221 are basically the same as those of the embodiment 11, and will not be repeated here.
按压部件222设置在空腔221的内部。其中,按压部件222为条状物,用于在盖部220封闭管部210的情况下,按压部件222对准样品管300的顶部,并在按压部件222与样品管300接触的位置施加一个基本垂直向下的压力,进而使样品管300快速被破管结构100刺破。The pressing member 222 is provided inside the cavity 221. Among them, the pressing member 222 is a strip, which is used to align the pressing member 222 with the top of the sample tube 300 when the lid 220 closes the tube 210, and apply a basic element at the position where the pressing member 222 is in contact with the sample tube 300. The vertical downward pressure causes the sample tube 300 to be quickly pierced by the broken tube structure 100.
利用按压部件222,可以在施加相同压力的情况下,提高单位面积的压力强度,提高样品管 300被破管结构100刺破的速度。By using the pressing member 222, the pressure intensity per unit area can be increased under the same pressure, and the speed at which the sample tube 300 is pierced by the broken tube structure 100 can be increased.
本实施例的使用方法如下:如图38A~38C所示,破坏或移除密封膜216,将装载有待检测样品的样品管300置入溶液腔211的内部;使用盖部220封闭管部210,在若干第二定位部件214的导向限位作用下,样品管300的底部对准设置于溶液腔211底部的破管结构100;在按压部件222的按压作用下,样品管300的底部被破管结构100刺破;在流动通道106的作用下,溶液腔211内的反应溶液与样品管300内的待检测样品混合,得到混合液;用盖部220封闭管部210;待反应一定时间后,倾斜管部210,使设置于试纸固定部件212内的免疫层析试纸的样品溶液接收端接触混合液,混合液在免疫层析试纸上进行层析作用;通过观察免疫层析试纸即可获知检测结果;在观察到检测结果之后,可以直接将生化试管200当做医疗废弃物处理,无须担忧生化试管200内的物质泄漏。The method of use of this embodiment is as follows: as shown in FIGS. 38A to 38C, destroy or remove the sealing film 216, and place the sample tube 300 loaded with the sample to be tested into the solution chamber 211; use the cap 220 to close the tube 210, Under the guiding and limiting action of several second positioning parts 214, the bottom of the sample tube 300 is aligned with the broken tube structure 100 arranged at the bottom of the solution chamber 211; under the pressing of the pressing part 222, the bottom of the sample tube 300 is broken. The structure 100 is punctured; under the action of the flow channel 106, the reaction solution in the solution chamber 211 is mixed with the sample to be tested in the sample tube 300 to obtain a mixed solution; the tube portion 210 is closed with the cap 220; after a certain period of reaction time, Tilt the tube portion 210 to make the sample solution receiving end of the immunochromatographic test paper arranged in the test paper fixing part 212 contact the mixed solution, and the mixed liquid is chromatographed on the immunochromatographic test paper; the detection can be obtained by observing the immunochromatographic test paper Result: After observing the test result, the biochemical test tube 200 can be directly treated as medical waste without worrying about the leakage of the material in the biochemical test tube 200.
实施例14Example 14
如图39~40所示,一种生化试管200,包括管部210、盖部220和连接部230,管部210和盖部220通过连接部230连接,盖部220用于对管部210进行封闭。As shown in Figures 39-40, a biochemical test tube 200 includes a tube part 210, a cover part 220, and a connecting part 230. The tube part 210 and the cover part 220 are connected by the connecting part 230. Closed.
其中,连接部230的连接关系、结构同实施例11基本相同,在此不再赘述。Wherein, the connection relationship and structure of the connecting portion 230 are basically the same as those of the embodiment 11, and will not be repeated here.
管部210包括溶液腔211、试纸固定部件212、若干第一定位部件213、若干第二定位部件214、密封膜216和第二嵌合部件217,其中,溶液腔211、试纸固定部件212、若干第一定位部件213、若干第二定位部件214和密封膜216的连接关系和结构同实施例12基本相同,在此不再赘述。The tube portion 210 includes a solution chamber 211, a test paper fixing part 212, a number of first positioning parts 213, a number of second positioning parts 214, a sealing film 216 and a second fitting part 217. Among them, the solution chamber 211, the test paper fixing part 212, a number of The connection relationship and structure of the first positioning component 213, the plurality of second positioning components 214, and the sealing film 216 are basically the same as those of the embodiment 12, and will not be repeated here.
第二嵌合部件217设置于管部210的顶部的内壁,并沿管部210的轴向间隔设置。The second fitting parts 217 are arranged on the inner wall of the top of the pipe 210 and are arranged at intervals along the axial direction of the pipe 210.
盖部220包括空腔221、按压部件222、密封部件223和第三嵌合部件224。其中,空腔221和按压部件222的连接关系、结构同实施例3基本相同,在此不再赘述。The cover 220 includes a cavity 221, a pressing member 222, a sealing member 223 and a third fitting member 224. Wherein, the connection relationship and structure of the cavity 221 and the pressing member 222 are basically the same as those in the third embodiment, and will not be repeated here.
密封部件223和第三嵌合部件224沿盖部220的轴向间隔设置。在盖部220封闭管部210的情况下,密封部件223位于盖部220的下侧,第三嵌合部件224位于密封部件223的上侧。The sealing member 223 and the third fitting member 224 are spaced apart in the axial direction of the cover 220. When the lid 220 closes the pipe 210, the sealing member 223 is located on the lower side of the lid 220, and the third fitting member 224 is located on the upper side of the sealing member 223.
在盖部220封闭管部210的情况下,密封部件223与管部210进行密封,第二嵌合部件217与第三嵌合部件224嵌合连接,以使盖部220与管部210进行紧密连接,提高生化试管200的防开启性能。When the lid 220 closes the tube 210, the sealing member 223 seals the tube 210, and the second fitting member 217 is fitted and connected to the third fitting member 224, so that the lid 220 and the tube 210 are tightly connected. Connect to improve the anti-opening performance of the biochemical test tube 200.
在其中的一个实施例中,密封部件223为环形凸起,其外径与管部210的顶部的内径相等。In one of the embodiments, the sealing member 223 is an annular protrusion whose outer diameter is equal to the inner diameter of the top of the tube 210.
在其中的一个实施例中,第二嵌合部件217为环形凸起,其外径大于管部210的顶部的的内径;第三嵌合部件224为环形凹槽,其与第二嵌合部件217相紧密配合。In one of the embodiments, the second fitting part 217 is an annular protrusion whose outer diameter is larger than the inner diameter of the top of the tube 210; the third fitting part 224 is an annular groove, which is connected to the second fitting part. 217 works closely together.
通过本实施例的密封部件、第二嵌合部件和第三嵌合部件,进一步地提高盖部与管部之间连 接的紧密程度,极大地提高了将盖部与管部分离的阻力,有效防止生化试管200内的溶液泄漏,避免污染环境,防止危害生命健康。Through the sealing component, the second fitting component and the third fitting component of this embodiment, the tightness of the connection between the cover part and the pipe part is further improved, and the resistance to separate the cover part and the pipe part is greatly improved, which is effective Prevent leakage of the solution in the biochemical test tube 200, avoid pollution of the environment, and prevent endangering life and health.
实施例15Example 15
本实施例涉及放置在实施例11~14的生化试管中的生化试纸。This embodiment relates to biochemical test papers placed in the biochemical test tubes of Examples 11-14.
在本实施例中,以生化试纸为免疫层析试纸为例进行说明。In this embodiment, the biochemical test paper is an immunochromatographic test paper as an example for description.
如图41~42所示,一种生化试纸400,包括基层401、层析膜402、吸水垫405、结合垫406和导引膜407,其中,导引膜407、结合垫406、层析膜402和吸水垫405依次设置在基层401。As shown in Figures 41 to 42, a biochemical test paper 400 includes a base layer 401, a chromatographic membrane 402, an absorbent pad 405, a binding pad 406, and a guiding membrane 407, wherein the guiding membrane 407, the binding pad 406, and the chromatographic membrane 402 and the absorbent pad 405 are arranged on the base layer 401 in sequence.
其中,生化试纸400的长度大于试纸固定部件212的高度。一般而言,生化试纸400的长度与试纸固定部件212的高度之间的差值为1mm~5mm,优选的的差值为2mm、3mm。Wherein, the length of the biochemical test paper 400 is greater than the height of the test paper fixing part 212. Generally speaking, the difference between the length of the biochemical test paper 400 and the height of the test paper fixing member 212 is 1 mm to 5 mm, and the preferable difference is 2 mm and 3 mm.
此外,在盖部220封闭管部110的情况下,生化试纸400的样品溶液接收端伸入盖部220的空腔221内。In addition, when the lid 220 closes the tube 110, the sample solution receiving end of the biochemical test paper 400 extends into the cavity 221 of the lid 220.
基层401由塑料制成,如不干胶塑料。The base layer 401 is made of plastic, such as self-adhesive plastic.
导引膜407设置在基层401的上表面,即导引膜407的下表面和基层401的上表面连接,如粘接。导引膜407的末端和结合垫406的前端接触,导引膜407向结合垫406传递溶液。The guiding film 407 is disposed on the upper surface of the base layer 401, that is, the lower surface of the guiding film 407 and the upper surface of the base layer 401 are connected, such as by bonding. The end of the guiding film 407 is in contact with the front end of the bonding pad 406, and the guiding film 407 transfers the solution to the bonding pad 406.
导引膜407的末端的上表面和结合垫406的前端的下表面接触,或,导引膜407的末端的下表面和结合垫406的前端的上表面接触。The upper surface of the end of the guiding film 407 is in contact with the lower surface of the front end of the bonding pad 406, or the lower surface of the end of the guiding film 407 is in contact with the upper surface of the front end of the bonding pad 406.
其中,导引膜407由纤维素膜制成。Among them, the guiding film 407 is made of cellulose film.
其中,导引膜407的厚度小于0.15mm。Wherein, the thickness of the guiding film 407 is less than 0.15 mm.
结合垫406设置在基层401的上表面,即结合垫406的下表面和基层401的上表面连接,如粘接。结合垫406的末端和层析膜402的前端接触,结合垫406向层析膜402传递溶液。具体地,结合垫406的末端的上表面和层析膜402的前端的下表面接触,或,结合垫406的末端的下表面和层析膜402的前端的上表面接触。The bonding pad 406 is disposed on the upper surface of the base layer 401, that is, the lower surface of the bonding pad 406 and the upper surface of the base layer 401 are connected, such as by bonding. The end of the bonding pad 406 is in contact with the front end of the chromatography membrane 402, and the bonding pad 406 transfers the solution to the chromatography membrane 402. Specifically, the upper surface of the end of the bonding pad 406 is in contact with the lower surface of the front end of the chromatography membrane 402, or the lower surface of the end of the bonding pad 406 is in contact with the upper surface of the front end of the chromatography membrane 402.
其中,结合垫406为胶体金垫。Among them, the bonding pad 406 is a colloidal gold pad.
其中,结合垫406由玻璃纤维、聚酯膜、纤维素滤纸、无纺布等材质制成。Among them, the bonding pad 406 is made of glass fiber, polyester film, cellulose filter paper, non-woven fabric and other materials.
其中,导引膜407的溶液层析速度小于结合垫406的溶液层析速度。Wherein, the solution chromatography speed of the guiding membrane 407 is lower than the solution chromatography speed of the binding pad 406.
层析膜402至少设置在基层401的上表面,即层析膜402的下表面和基层401的上表面连接,如粘接。层析膜402的末端和吸水垫405的末端接触,层析膜402向吸水垫405传递溶液。The chromatographic membrane 402 is arranged at least on the upper surface of the base layer 401, that is, the lower surface of the chromatographic membrane 402 and the upper surface of the base layer 401 are connected, such as by bonding. The end of the chromatographic membrane 402 is in contact with the end of the absorbent pad 405, and the chromatographic membrane 402 transfers the solution to the absorbent pad 405.
其中,层析膜402还设置有检测线403和质控线404,沿着层析膜402的前端至末端依次设置。Wherein, the chromatographic membrane 402 is further provided with a detection line 403 and a quality control line 404, which are sequentially arranged along the front end to the end of the chromatographic membrane 402.
其中,层析膜402由硝酸纤维素膜制成。Among them, the chromatographic membrane 402 is made of nitrocellulose membrane.
吸水垫405至少设置在基层401的下表面,即吸水垫405的上表面和基层401的下表面连接,如粘接。吸水垫405的末端和层析膜402的末端接触。The absorbent pad 405 is at least disposed on the lower surface of the base layer 401, that is, the upper surface of the absorbent pad 405 and the lower surface of the base layer 401 are connected, such as by bonding. The end of the absorbent pad 405 is in contact with the end of the chromatography membrane 402.
其中,吸水垫405为吸水纸。Among them, the absorbent pad 405 is absorbent paper.
其中,层析膜402的末端和吸水垫405的末端在基层401的末端接触并进行溶液传递。Wherein, the end of the chromatographic membrane 402 and the end of the absorbent pad 405 are in contact with the end of the base layer 401 and the solution is transferred.
在本实施例的第一个实施方式中,层析膜402的末端超出基层401的末端一定距离,吸水垫405的末端超出基层401的末端一定距离,层析膜402的末端和吸水垫405的末端接触并进行溶液传递,即层析膜402的末端的下表面和吸水垫405的末端的上表面接触并进行溶液传递。在这种实施方式中,层析膜402、基层401和吸水垫405形成一个三明治结构。In the first implementation of this embodiment, the end of the chromatography membrane 402 exceeds the end of the base layer 401 by a certain distance, the end of the absorbent pad 405 exceeds the end of the base layer 401 by a certain distance, the end of the chromatography membrane 402 and the end of the absorbent pad 405 The ends contact and transfer the solution, that is, the lower surface of the end of the chromatography membrane 402 and the upper surface of the end of the absorbent pad 405 contact and transfer the solution. In this embodiment, the chromatographic membrane 402, the base layer 401 and the absorbent pad 405 form a sandwich structure.
在本实施例的第二个实施方式中,层析膜402还设置在基层401的下表面,即层析膜402的末端在基层401的末端向下弯折。具体地,层析膜402的末端的上表面和吸水垫405的末端的上表面接触并进行溶液传递,或层析膜402的末端的下表面和吸水垫405的末端的下表面接触并进行溶液传递。In the second implementation of this embodiment, the chromatography membrane 402 is also disposed on the lower surface of the base layer 401, that is, the end of the chromatography membrane 402 is bent downward at the end of the base layer 401. Specifically, the upper surface of the end of the chromatography membrane 402 is in contact with the upper surface of the end of the absorbent pad 405 and the solution is transferred, or the lower surface of the end of the chromatography membrane 402 and the lower surface of the end of the absorbent pad 405 are in contact and solution transfer.
在该实施方式中,位于基层401的上表面的层析膜402的长度大于位于基层401的下表面的层析膜402的长度;或者,位于基层401的上表面的层析膜402的长度等于位于基层401的下表面的层析膜402的长度;或者,位于基层401的上表面的层析膜402的长度小于位于基层401的下表面的层析膜402的长度。In this embodiment, the length of the chromatography membrane 402 located on the upper surface of the base layer 401 is greater than the length of the chromatography membrane 402 located on the lower surface of the base layer 401; or, the length of the chromatography membrane 402 located on the upper surface of the base layer 401 is equal to The length of the chromatography membrane 402 located on the lower surface of the base layer 401; or, the length of the chromatography membrane 402 located on the upper surface of the base layer 401 is less than the length of the chromatography membrane 402 located on the lower surface of the base layer 401.
优选地,位于基层401的上表面的层析膜402的长度大于位于基层401的下表面的层析膜402的长度Preferably, the length of the chromatography membrane 402 located on the upper surface of the base layer 401 is greater than the length of the chromatography membrane 402 located on the lower surface of the base layer 401
在本实施例的第三个实施方式中,吸水垫405还设置在基层401的上表面,即吸水垫405的末端在基层401的末端向上弯折。具体地,吸水垫405的末端的上表面和层析膜402的末端的上表面接触并进行溶液传递,或吸水垫405的末端的下表面和层析膜402的末端的下表面接触并进行溶液传递。In the third implementation of this embodiment, the absorbent pad 405 is also disposed on the upper surface of the base layer 401, that is, the end of the absorbent pad 405 is bent upward at the end of the base layer 401. Specifically, the upper surface of the end of the absorbent pad 405 is in contact with the upper surface of the end of the chromatography membrane 402 and the solution is transferred, or the lower surface of the end of the absorbent pad 405 and the lower surface of the end of the chromatography membrane 402 are in contact and solution transfer.
在该实施方式中,位于基层401的上表面的吸水垫405的长度大于位于基层401的下表面的吸水垫405的长度;或者,位于基层401的上表面的吸水垫405的长度等于位于基层401的下表面的吸水垫405的长度;或者,位于基层401的上表面的吸水垫405的长度小于位于基层401的下表面的吸水垫405的长度。In this embodiment, the length of the absorbent pad 405 located on the upper surface of the base layer 401 is greater than the length of the absorbent pad 405 located on the lower surface of the base layer 401; or, the length of the absorbent pad 405 located on the upper surface of the base layer 401 is equal to the length of the absorbent pad 405 located on the upper surface of the base layer 401 Or, the length of the absorbent pad 405 on the upper surface of the base layer 401 is less than the length of the absorbent pad 405 on the lower surface of the base layer 401.
优选地,位于基层401的上表面的吸水垫405的长度小于位于基层401的下表面的吸水垫405的长度。Preferably, the length of the absorbent pad 405 located on the upper surface of the base layer 401 is smaller than the length of the absorbent pad 405 located on the lower surface of the base layer 401.
此外,为了确保层析膜402的末端和吸水垫405的末端接触,在层析膜402的末端和吸水垫405的末端还设置有薄膜。薄膜包覆层析膜402和吸水垫405,以使层析膜402和吸水垫405保持接触。In addition, in order to ensure that the end of the chromatography membrane 402 and the end of the absorbent pad 405 are in contact, a thin film is also provided at the end of the chromatography membrane 402 and the end of the absorbent pad 405. The thin film covers the chromatographic membrane 402 and the absorbent pad 405 so that the chromatographic membrane 402 and the absorbent pad 405 are kept in contact.
在本实施例中,生化试纸400的长度为2cm~4cm,优选的为2.8cm、3.0cm、3.2cm、3.5cm。In this embodiment, the length of the biochemical test paper 400 is 2 cm to 4 cm, preferably 2.8 cm, 3.0 cm, 3.2 cm, or 3.5 cm.
本实施例的使用方法如下:将生化试纸400放入生化试管200的试纸固定部件212中,使生化试纸400的样品溶液接收端朝上设置(即导引膜407);破坏或移除密封膜216,将装载有待检测样品的样品管300置入溶液腔211的内部,在若干第二定位部件214的导向限位作用下,样品管300的底部对准设置于溶液腔211底部的破管结构100,并被破管结构100刺破;在流动通道106的作用下,溶液腔211内的反应溶液与样品管300内的待检测样品混合,得到混合液;用盖部220封闭管部210;待反应一定时间后,倾斜管部210,使设置于试纸固定部件212内的生化试纸400的导引膜407接触混合液,混合液在生化试纸400上进行层析作用;通过观察生化试纸400即可获知检测结果;在观察到检测结果之后,可以直接将生化试管200当做医疗废弃物处理,无须担忧生化试管200内的物质泄漏。The usage method of this embodiment is as follows: put the biochemical test paper 400 into the test paper fixing part 212 of the biochemical test tube 200, and set the sample solution receiving end of the biochemical test paper 400 upward (ie the guiding film 407); destroy or remove the sealing film 216. Place the sample tube 300 loaded with the sample to be tested into the solution chamber 211, and under the guiding and limiting action of the plurality of second positioning members 214, the bottom of the sample tube 300 is aligned with the broken tube structure provided at the bottom of the solution chamber 211 100, and punctured by the broken tube structure 100; under the action of the flow channel 106, the reaction solution in the solution chamber 211 is mixed with the sample to be tested in the sample tube 300 to obtain a mixed solution; the tube 210 is closed with the cap 220; After reacting for a certain period of time, tilt the tube 210 to make the guiding film 407 of the biochemical test paper 400 arranged in the test paper fixing part 212 contact the mixed liquid, and the mixed liquid undergoes chromatographic action on the biochemical test paper 400; by observing the biochemical test paper 400, The test results can be obtained; after observing the test results, the biochemical test tube 200 can be directly treated as medical waste, and there is no need to worry about the leakage of the material in the biochemical test tube 200.
实施例16Example 16
本实施例涉及放置在实施例11~14的生化试管中的生化试纸。This embodiment relates to biochemical test papers placed in the biochemical test tubes of Examples 11-14.
在本实施例中,以生化试纸为免疫层析试纸为例进行说明。In this embodiment, the biochemical test paper is an immunochromatographic test paper as an example for description.
如图43~44所示,一种生化试纸400,包括基层401、层析膜402、吸水垫405、结合垫406、导引膜407和样品垫408,其中,样品垫408、导引膜407、结合垫406、层析膜402和吸水垫405设置在基层401。As shown in Figures 43 to 44, a biochemical test paper 400 includes a base layer 401, a chromatographic membrane 402, an absorbent pad 405, a binding pad 406, a guiding film 407, and a sample pad 408, wherein the sample pad 408 and the guiding film 407 , The bonding pad 406, the chromatographic membrane 402 and the water absorption pad 405 are arranged on the base layer 401.
其中,基层401、层析膜402、吸水垫405和结合垫406连接关系、结构和构成同实施例15基本相同,在此不再赘述。The connection relationship, structure and composition of the base layer 401, the chromatographic membrane 402, the water-absorbing pad 405 and the bonding pad 406 are basically the same as those in Embodiment 15, and will not be repeated here.
样品垫408设置在基层401的上表面,即样品垫408的下表面和基层401的上表面连接,如粘接。The sample pad 408 is disposed on the upper surface of the base layer 401, that is, the lower surface of the sample pad 408 and the upper surface of the base layer 401 are connected, such as by bonding.
其中,样品垫408由玻璃纤维、聚酯膜、纤维素滤纸、无纺布等材质制成。The sample pad 408 is made of glass fiber, polyester film, cellulose filter paper, non-woven fabric and other materials.
在本实施例的第一个实施方式中,样品垫408的末端和导引膜407的前端接触,样品垫408向导引膜407传递溶液。具体地,样品垫408的末端的上表面和导引膜407的前端的下表面接触,或,样品垫408的末端的下表面和导引膜407的前端的上表面接触。In the first implementation of this embodiment, the end of the sample pad 408 is in contact with the front end of the guiding film 407, and the sample pad 408 transfers the solution to the guiding film 407. Specifically, the upper surface of the end of the sample pad 408 is in contact with the lower surface of the front end of the guiding film 407, or the lower surface of the end of the sample pad 408 is in contact with the upper surface of the front end of the guiding film 407.
在本实施例的第二个实施方式中,样品垫408的前端与导引膜407的末端接触,导引膜407向样品垫408传递溶液。具体地,导引膜407的末端的上表面和样品垫408的前端的下表面接触, 或,导引膜407的末端的下表面和样品垫408的前端的上表面接触。In the second implementation of this embodiment, the front end of the sample pad 408 is in contact with the end of the guiding film 407, and the guiding film 407 transfers the solution to the sample pad 408. Specifically, the upper surface of the end of the guiding film 407 is in contact with the lower surface of the front end of the sample pad 408, or the lower surface of the end of the guiding film 407 is in contact with the upper surface of the front end of the sample pad 408.
样品垫408的末端与结合垫406的前端接触,样品垫408向结合垫406传递溶液。具体地,样品垫408的末端的上表面和结合垫406的前端的下表面接触,或,样品垫408的末端的下表面和结合垫406的前端的上表面接触。The end of the sample pad 408 is in contact with the front end of the bonding pad 406, and the sample pad 408 transfers the solution to the bonding pad 406. Specifically, the upper surface of the end of the sample pad 408 is in contact with the lower surface of the front end of the bonding pad 406, or the lower surface of the end of the sample pad 408 is in contact with the upper surface of the front end of the bonding pad 406.
在本实施例的第三个实施方式中,如图13~14所示,免疫层析试纸包括两个导引膜407分别设置在样品垫408的前侧和后侧,即第一个导引膜407的末端与样品垫408的前端接触,第一个导引膜407向样品垫408传递溶液。具体地,第一个导引膜407的末端的上表面和样品垫408的前端的下表面接触,或,第一个导引膜407的末端的下表面和样品垫408的前端的上表面接触。In the third implementation of this embodiment, as shown in FIGS. 13-14, the immunochromatographic test paper includes two guiding films 407 respectively arranged on the front and back sides of the sample pad 408, that is, the first guiding film 407 The end of the membrane 407 is in contact with the front end of the sample pad 408, and the first guiding membrane 407 transfers the solution to the sample pad 408. Specifically, the upper surface of the end of the first guiding film 407 is in contact with the lower surface of the front end of the sample pad 408, or the lower surface of the end of the first guiding film 407 is in contact with the upper surface of the front end of the sample pad 408 .
样品垫408的末端与第二个导引膜407接触,样品垫408向第二个导引膜407传递溶液。样品垫408的末端的上表面和第二个导引膜407的前端的下表面接触,或,样品垫408的末端的下表面和第二个导引膜407的前端的上表面接触。The end of the sample pad 408 is in contact with the second guiding film 407, and the sample pad 408 transfers the solution to the second guiding film 407. The upper surface of the end of the sample pad 408 is in contact with the lower surface of the front end of the second guiding film 407, or the lower surface of the end of the sample pad 408 is in contact with the upper surface of the front end of the second guiding film 407.
其中,在导引膜407仅有一个的情况下,导引膜407可以为第一导引膜;在导引膜407为两个的情况下,靠近层析膜402的导引膜407可以为第一导引膜,远离层析膜402的导引膜407可以为第二导引膜。Wherein, when there is only one guiding film 407, the guiding film 407 may be the first guiding film; when there are two guiding films 407, the guiding film 407 close to the chromatographic membrane 402 may be The first guiding membrane, and the guiding membrane 407 away from the chromatographic membrane 402 may be the second guiding membrane.
在本实施例中,样品垫408的溶液层析速度大于导引膜407的溶液层析速度。In this embodiment, the solution chromatography speed of the sample pad 408 is greater than the solution chromatography speed of the guiding membrane 407.
在本实施例中,生化试纸400的长度为2cm~4cm,优选的为3.2cm、3.5cm。In this embodiment, the length of the biochemical test paper 400 is 2 cm to 4 cm, preferably 3.2 cm, 3.5 cm.
本实施例的使用方法同实施例15基本相同,在此不再赘述。The usage method of this embodiment is basically the same as that of Embodiment 15, and will not be repeated here.
实施例17Example 17
本实施例涉及放置在实施例11~14的生化试管中的生化试纸。This embodiment relates to biochemical test papers placed in the biochemical test tubes of Examples 11-14.
在本实施例中,以生化试纸为免疫层析试纸为例进行说明。In this embodiment, the biochemical test paper is an immunochromatographic test paper as an example for description.
如图45~46所示,一种生化试纸400,包括基层401、层析膜402、吸水垫405、结合垫406、导引膜407和样品限量膜409,其中,样品限量膜409、导引膜407、结合垫406、层析膜402和吸水垫405依次设置在基层401。As shown in Figures 45 to 46, a biochemical test paper 400 includes a base layer 401, a chromatographic membrane 402, an absorbent pad 405, a binding pad 406, a guiding film 407, and a sample limiting film 409. The sample limiting film 409, the guiding film The membrane 407, the bonding pad 406, the chromatographic membrane 402 and the water absorption pad 405 are arranged on the base layer 401 in sequence.
其中,基层401、层析膜402、吸水垫405、结合垫406和导引膜407的连接关系、结构和构成同实施例16基本相同,在此不再赘述。Among them, the connection relationship, structure and composition of the base layer 401, the chromatographic membrane 402, the water-absorbing pad 405, the bonding pad 406 and the guiding membrane 407 are basically the same as those of Embodiment 16, and will not be repeated here.
样品限量膜409设置在基层401的上表面,即样品限量膜409的下表面与基层401的上表面连接,如粘接。样品限量膜409的末端与导引膜407的前端接触,样品限量膜409向导引膜407传递溶液。具体地,样品限量膜409的末端的上表面与导引膜407的前端的下表面接触,或,样品限量膜409的末端的下表面与导引膜407的前端的上表面接触。The sample limiting film 409 is disposed on the upper surface of the base layer 401, that is, the lower surface of the sample limiting film 409 is connected to the upper surface of the base layer 401, such as by bonding. The end of the sample limiting film 409 is in contact with the front end of the guiding film 407, and the sample limiting film 409 transfers the solution to the guiding film 407. Specifically, the upper surface of the end of the sample limiting film 409 is in contact with the lower surface of the leading end of the guiding film 407, or the lower surface of the end of the sample limiting film 409 is in contact with the upper surface of the leading end of the guiding film 407.
其中,样品限量膜409的吸液饱和容积为2~20μl,能够吸收微量样品。Among them, the liquid absorption saturation volume of the sample limiting membrane 409 is 2-20 μl, which can absorb a small amount of samples.
其中,样品限量膜409由玻璃纤维、聚酯膜、纤维素滤纸等材质制成。Among them, the sample limit film 409 is made of glass fiber, polyester film, cellulose filter paper and other materials.
在本实施例中,生化试纸400的长度为2cm~4cm,优选的为3.3cm、3.5cm、3.7cm。In this embodiment, the length of the biochemical test paper 400 is 2 cm to 4 cm, preferably 3.3 cm, 3.5 cm, 3.7 cm.
本实施例的使用方法同实施例15基本相同,在此不再赘述。The usage method of this embodiment is basically the same as that of Embodiment 15, and will not be repeated here.
实施例18Example 18
本实施例涉及放置在实施例11~14的生化试管中的生化试纸。This embodiment relates to biochemical test papers placed in the biochemical test tubes of Examples 11-14.
在本实施例中,以生化试纸为免疫层析试纸为例进行说明。In this embodiment, the biochemical test paper is an immunochromatographic test paper as an example for description.
如图47~48所示,一种生化试纸400,包括基层401、层析膜402、吸水垫405、结合垫406、导引膜407、样品垫408和样品限量膜409,其中,样品限量膜409、导引膜407、样品垫408、结合垫406、层析膜402和吸水垫405设置在基层401。As shown in Figures 47 to 48, a biochemical test paper 400 includes a base layer 401, a chromatographic membrane 402, an absorbent pad 405, a binding pad 406, a guiding membrane 407, a sample pad 408, and a sample limit film 409, wherein the sample limit film 409, the guiding membrane 407, the sample pad 408, the binding pad 406, the chromatography membrane 402, and the water absorption pad 405 are arranged on the base layer 401.
其中,基层401、层析膜402、吸水垫405、结合垫406、导引膜407和样品垫408的连接关系、结构和构成同实施例16的第二个实施方式、第三个实施方式基本相同,在此不再赘述。Among them, the connection relationship, structure and composition of the base layer 401, the chromatographic membrane 402, the absorbent pad 405, the bonding pad 406, the guiding membrane 407 and the sample pad 408 are basically the same as those of the second and third embodiments of Example 16. The same, so I won’t repeat them here.
样品限量膜409设置在基层401的上表面,即样品限量膜409的下表面与基层401的上表面连接,如粘接。样品限量膜409的末端与导引膜407的前端接触,样品限量膜409向导引膜407传递溶液。具体地,样品限量膜409的末端的上表面与导引膜407的前端的下表面接触,或,样品限量膜409的末端的下表面与导引膜407的前端的上表面接触。The sample limiting film 409 is disposed on the upper surface of the base layer 401, that is, the lower surface of the sample limiting film 409 is connected to the upper surface of the base layer 401, such as by bonding. The end of the sample limiting film 409 is in contact with the front end of the guiding film 407, and the sample limiting film 409 transfers the solution to the guiding film 407. Specifically, the upper surface of the end of the sample limiting film 409 is in contact with the lower surface of the leading end of the guiding film 407, or the lower surface of the end of the sample limiting film 409 is in contact with the upper surface of the leading end of the guiding film 407.
其中,样品限量膜409的吸液饱和容积为2~20μl,能够吸收微量样品。Among them, the liquid absorption saturation volume of the sample limiting membrane 409 is 2-20 μl, which can absorb a small amount of samples.
其中,样品限量膜409由玻璃纤维、聚酯膜、纤维素滤纸等材质制成。Among them, the sample limit film 409 is made of glass fiber, polyester film, cellulose filter paper and other materials.
在本实施例中,生化试纸400的长度为2cm~4cm,优选的为3.6cm、3.8cm。In this embodiment, the length of the biochemical test paper 400 is 2 cm to 4 cm, preferably 3.6 cm or 3.8 cm.
本实施例的使用方法同实施例15基本相同,在此不再赘述。The usage method of this embodiment is basically the same as that of Embodiment 15, and will not be repeated here.
实施例19Example 19
本实施例涉及放置在实施例11~14的生化试管中的生化试纸。This embodiment relates to biochemical test papers placed in the biochemical test tubes of Examples 11-14.
在本实施例中,以生化试纸为免疫层析试纸为例进行说明。In this embodiment, the biochemical test paper is an immunochromatographic test paper as an example for description.
如图49所示,一种生化试纸400,包括基层401、层析膜402、吸水垫405、结合垫406、导引膜407和透明保护膜410,其中,导引膜407、结合垫406、层析膜402和吸水垫405依次设置在基层401。As shown in FIG. 49, a biochemical test paper 400 includes a base layer 401, a chromatographic membrane 402, a water absorption pad 405, a bonding pad 406, a guiding film 407, and a transparent protective film 410, wherein the guiding film 407, the bonding pad 406, The chromatographic membrane 402 and the absorbent pad 405 are sequentially arranged on the base layer 401.
其中,基层401、层析膜402、吸水垫405、结合垫406和导引膜407的连接关系、结构和构成同实施例15基本相同,在此不再赘述。Among them, the connection relationship, structure and composition of the base layer 401, the chromatographic membrane 402, the water-absorbing pad 405, the bonding pad 406 and the guiding membrane 407 are basically the same as those of Embodiment 15, and will not be repeated here.
透明保护膜410的下表面至少覆盖结合垫406和层析膜402。The lower surface of the transparent protective film 410 covers at least the bonding pad 406 and the chromatographic film 402.
在本实施例中,利用透明保护膜410可以避免结合垫406和层析膜402的接触外源性含水混合物,提高层析试纸的检测结果的正确率。In this embodiment, the use of the transparent protective film 410 can prevent the bonding pad 406 and the chromatography membrane 402 from contacting the exogenous aqueous mixture, and improve the accuracy of the detection result of the chromatography test paper.
此外,透明保护膜410还可以应用在实施例16~实施例18的免疫层析试纸。In addition, the transparent protective film 410 can also be applied to the immunochromatographic test papers of Examples 16-18.
实施例20Example 20
如图50所示,生化试纸400还包括透明中空管500,透明中空管500包裹生化试纸400于透明中空管500的内部,即生化试纸400设置于透明中空管500的内部。As shown in FIG. 50, the biochemical test paper 400 further includes a transparent hollow tube 500. The transparent hollow tube 500 wraps the biochemical test paper 400 inside the transparent hollow tube 500, that is, the biochemical test paper 400 is disposed inside the transparent hollow tube 500.
透明中空管500的内表面为疏水表面。The inner surface of the transparent hollow tube 500 is a hydrophobic surface.
透明中空管500的第一端为封闭端,其第二端为开口端,设置开口端的目的是便于将生化试纸400从开口向透明中空管500的内部移动。The first end of the transparent hollow tube 500 is a closed end, and the second end is an open end. The purpose of setting the open end is to facilitate the movement of the biochemical test paper 400 from the opening to the inside of the transparent hollow tube 500.
此外,生化试纸400的样品溶液接收端位于透明中空管500的开口端。In addition, the sample solution receiving end of the biochemical test paper 400 is located at the open end of the transparent hollow tube 500.
其中,透明中空管500由透明材料制成,如塑料、热塑性树脂,便于观察生化试纸400的检测或诊断结果。Wherein, the transparent hollow tube 500 is made of a transparent material, such as plastic or thermoplastic resin, which is convenient for observing the detection or diagnosis result of the biochemical test paper 400.
在其中的一个实施例中,如图51所示,透明中空管500的开口端的第二端的横截面的宽度大于开口端的第一端的横截面的内径。优选地,透明中空管500的开口端的横截面的宽度由开口端的第二端向开口端的第一端递减。In one of the embodiments, as shown in FIG. 51, the width of the cross section of the second end of the open end of the transparent hollow tube 500 is larger than the inner diameter of the cross section of the first end of the open end. Preferably, the width of the cross section of the open end of the transparent hollow tube 500 decreases from the second end of the open end to the first end of the open end.
如图52所示,将套设有透明中空管500的生化试纸400放入生化试管200的试纸固定部件212,可以避免生化试纸400直接与试纸固定部件212的内表面接触,防止试纸固定部件212的内表面的表面张力影响生化试纸400的吸附速率。As shown in Figure 52, putting the biochemical test paper 400 covered with a transparent hollow tube 500 into the test paper fixing part 212 of the biochemical test tube 200 can prevent the biochemical test paper 400 from directly contacting the inner surface of the test paper fixing part 212 and prevent the test paper fixing part The surface tension of the inner surface of 212 affects the adsorption rate of the biochemical test paper 400.
实施例21Example 21
如图53~55所示,一种导热盲管600,包括盲管体610以及设置于盲管体610底部的导热部件620,其中,盲管体610两端具有开口;导热部件620连接于盲管体610底端开口,且导热部件620将盲管体610底端开口密封;其中,导热部件620的导热系数λ>1.0W/(m·K)。As shown in Figures 53 to 55, a thermally conductive blind tube 600 includes a blind tube body 610 and a thermally conductive component 620 arranged at the bottom of the blind tube body 610, wherein the blind tube body 610 has openings at both ends; the thermally conductive component 620 is connected to the blind tube body 610. The bottom end of the tube body 610 is open, and the heat-conducting component 620 seals the bottom end of the blind tube body 610; the thermal conductivity of the heat-conducting component 620 is λ>1.0 W/(m·K).
其中,本实施例中,导热部件620的材料可以为金属,当导热部件620的材料为金属时,导热部件620与盲管体610嵌合连接;Wherein, in this embodiment, the material of the heat-conducting component 620 may be metal, and when the material of the heat-conducting component 620 is metal, the heat-conducting component 620 is fitted and connected with the blind tube body 610;
导热部件620的材料可以为导热塑料,当导热部件620的材料为导热塑料时,导热部件620与盲管体610嵌合连接可一体注塑;且该导热塑料的导热系数λ>1.0W/(m·K),优选为λ=1.2W/(m·K)。The material of the heat-conducting component 620 can be a heat-conducting plastic. When the material of the heat-conducting component 620 is a heat-conducting plastic, the heat-conducting component 620 and the blind tube body 610 can be fitted and connected as an integral injection molding; and the thermal conductivity of the heat-conducting plastic λ>1.0W/(m ·K), preferably λ=1.2W/(m·K).
本实施例中,盲管体610的材料可以为普通塑料。In this embodiment, the material of the blind tube body 610 may be ordinary plastic.
具体应用中,盲管体610底部直接采用导热部件620密封,不仅提高了导热性能,且使得导 热盲管600的结构简单,便于生产制造,节约成本。In specific applications, the bottom of the blind tube body 610 is directly sealed with the heat conducting component 620, which not only improves the thermal conductivity, but also makes the structure of the blind tube 600 simple, which is convenient for manufacturing and saves costs.
在一些实施例中,导热部件620包括导热块621,导热块621与盲管体610嵌合连接。In some embodiments, the heat-conducting component 620 includes a heat-conducting block 621, and the heat-conducting block 621 is fitted and connected with the blind tube body 610.
具体地,导热块621上设置有第四嵌合部件,其中,第四嵌合部件包括设置于导热块621上的凸环622以及设置于盲管体610上与凸环622配合连接的凹槽611。Specifically, a fourth fitting part is provided on the heat conducting block 621, where the fourth fitting part includes a convex ring 622 arranged on the heat conducting block 621 and a groove arranged on the blind tube body 610 to be matedly connected with the convex ring 622 611.
优选的,凸环622设置有两个,其中,一个凸环622与凹槽611连接,另一个凸环622与盲管体610内壁贴合,提高密封性。Preferably, two convex rings 622 are provided, of which one convex ring 622 is connected to the groove 611, and the other convex ring 622 is attached to the inner wall of the blind tube body 610 to improve the sealing performance.
导热盲管600还包括盲管盖630,盲管盖630与盲管体610为一体成型结构。具体地,盲管盖630顶部呈八字形结构,使得盲管盖630具有一定导向作用,当导热盲管600与生化试管200配合使用时,导热盲管600可恰好放入生化试管200内,便于检测操作。The thermally conductive blind tube 600 further includes a blind tube cover 630, and the blind tube cover 630 and the blind tube body 610 are integrally formed. Specifically, the top of the blind tube cover 630 has a figure-eight-shaped structure, so that the blind tube cover 630 has a certain guiding effect. When the thermally conductive blind tube 600 is used in conjunction with the biochemical test tube 200, the thermally conductive blind tube 600 can be placed in the biochemical test tube 200 for convenience. Detection operation.
具体地,导热盲管600在生化试管200的若干第二定位部件214的作用下进入到生化试管200的内部,并与位于生化试管200的底部的破管结构100相接触,并被破管结构100所破坏。Specifically, the heat-conducting blind tube 600 enters the inside of the biochemical test tube 200 under the action of several second positioning members 214 of the biochemical test tube 200, and contacts the broken tube structure 100 at the bottom of the biochemical test tube 200, and is broken by the tube structure. 100 destroyed.
以上所述仅为本发明较佳的实施例,并非因此限制本发明的实施方式及保护范围,对于本领域技术人员而言,应当能够意识到凡运用本发明说明书及图示内容所作出的等同替换和显而易见的变化所得到的方案,均应当包含在本发明的保护范围内。The above descriptions are only preferred embodiments of the present invention, and do not limit the implementation and protection scope of the present invention. For those skilled in the art, they should be able to realize that all equivalents made by using the description and illustrations of the present invention are equivalent. The solutions obtained by substitutions and obvious changes should all be included in the protection scope of the present invention.

Claims (30)

  1. 一种破管结构,其特征在于,包括:A broken pipe structure, characterized in that it comprises:
    本体;Ontology
    至少两破管部件,所述破管部件设置于所述本体的上方,所述破管部件包括:At least two broken pipe parts, the broken pipe parts are arranged above the body, and the broken pipe parts include:
    切割元件,所述切割元件设置于所述破管部件的上方;A cutting element, the cutting element is arranged above the broken pipe component;
    撑开元件,所述撑开元件设置于所述破管部件的下方,并与所述切割元件连接;Expansion element, the expansion element is arranged below the broken pipe part and connected with the cutting element;
    导流部件,在相邻两所述破管部件之间设置所述导流部件。The flow guiding part is arranged between two adjacent broken pipe parts.
  2. 根据权利要求1所述的破管结构,其特征在于,所述破管部件包括:The broken pipe structure according to claim 1, wherein the broken pipe component comprises:
    第一破管部件,所述第一破管部件包括:The first pipe breaking component, the first pipe breaking component includes:
    第一切割元件,所述第一切割元件设置于所述第一破管部件的上方;A first cutting element, the first cutting element is arranged above the first pipe breaking component;
    第一撑开元件,所述第一撑开元件设置于所述第一破管部件的下方,位于所述第一切割元件的下方,并与所述第一切割元件连接;A first expansion element, the first expansion element is arranged below the first pipe breaking component, located below the first cutting element, and connected to the first cutting element;
    和/或and / or
    第二破管部件,所述第二破管部件包括:The second pipe breaking component, the second pipe breaking component includes:
    第二切割元件,所述第二切割元件设置于所述第二破管部件的上方;A second cutting element, the second cutting element is arranged above the second pipe breaking component;
    第三切割元件,所述第三切割元件设置于所述第二破管部件的上方,位于所述第二切割元件的下方,并与所述第二切割元件连接;A third cutting element, the third cutting element is arranged above the second pipe breaking component, located below the second cutting element, and connected to the second cutting element;
    第二撑开元件,所述第二撑开元件设置于所述第二破管部件的下方,位于所述第三切割元件的下方,并与所述第三切割元件连接。The second expansion element, the second expansion element is arranged under the second pipe breaking component, located under the third cutting element, and connected with the third cutting element.
  3. 根据权利要求2所述的破管结构,其特征在于,在所述破管部件包括所述第一破管部件以及所述第二破管部件的情况下,所述第一破管部件的数量与所述第二破管部件的数量相等或不相等。The broken pipe structure according to claim 2, wherein when the broken pipe part includes the first broken pipe part and the second broken pipe part, the number of the first broken pipe part The number of the second pipe breaking parts is equal or not equal.
  4. 根据权利要求3所述的破管结构,其特征在于,在所述第一破管部件的数量与所述第二破管部件的数量相等、且所述第一破管部件的数量与所述第二破管部件的数量均至少为两个的情况下,相邻两所述第一破管部件之间设置一所述第二破管部件、相邻两所述第二破管部件之间设置一所述第一破管部件。The broken pipe structure according to claim 3, wherein the number of the first broken pipe parts is equal to the number of the second broken pipe parts, and the number of the first broken pipe parts is equal to the number of the second broken pipe parts. In the case where the number of second broken pipe parts is at least two, one second broken pipe part is arranged between two adjacent first broken pipe parts, and between two adjacent second broken pipe parts A said first broken pipe component is provided.
  5. 根据权利要求2~4任一所述的破管结构,其特征在于,所述第一切割元件包括第一倾斜边,所述第一倾斜边与水平面形成第一夹角;The broken pipe structure according to any one of claims 2 to 4, wherein the first cutting element comprises a first inclined edge, and the first inclined edge forms a first angle with a horizontal plane;
    所述第二切割元件包括第二倾斜边,所述第二倾斜边与水平面形成第二夹角;The second cutting element includes a second inclined side, and the second inclined side forms a second included angle with the horizontal plane;
    所述第三切割元件包括第三倾斜边,所述第三倾斜边与水平面形成第三夹角;The third cutting element includes a third inclined side, and the third inclined side forms a third angle with the horizontal plane;
    其中,所述第一夹角与所述第二夹角相等或不等,所述第一夹角与所述第三夹角相等或不等,所述第二夹角与所述第三夹角不等。Wherein, the first included angle and the second included angle are equal or unequal, the first included angle and the third included angle are equal or unequal, and the second included angle is equal to or unequal to the third included angle. The angles vary.
  6. 根据权利要求2~5任一所述的破管结构,其特征在于,所述第一破管部件的水平宽度与所述第二破管部件的水平宽度相等或不等。The broken pipe structure according to any one of claims 2 to 5, wherein the horizontal width of the first broken pipe part is equal to or different from the horizontal width of the second broken pipe part.
  7. 根据权利要求2~6任一所述的破管结构,其特征在于,所述第一破管部件的水平宽度与所述第二破管部件的水平宽度之和小于等于所述本体的最小水平宽度。The broken pipe structure according to any one of claims 2 to 6, wherein the sum of the horizontal width of the first broken pipe part and the horizontal width of the second broken pipe part is less than or equal to the minimum level of the body width.
  8. 根据权利要求1~7任一所述的破管结构,其特征在于,还包括:The broken pipe structure according to any one of claims 1-7, further comprising:
    连接部件,所述连接部件设置于所述本体的内部。The connecting part is arranged inside the body.
  9. 根据权利要求8所述的破管结构,其特征在于,还包括:The broken pipe structure according to claim 8, further comprising:
    第一嵌合部件,所述第一嵌合部件设置于所述连接部件的内壁。The first fitting member is provided on the inner wall of the connecting member.
  10. 一种生化试管,包括如权利要求1~9任一所述的破管结构,其特征在于,所述破管结构设置于所述生化试管的溶液腔的底部。A biochemical test tube, comprising the broken tube structure according to any one of claims 1-9, wherein the broken tube structure is arranged at the bottom of the solution cavity of the biochemical test tube.
  11. 根据权利要求10所述的生化试管,其特征在于,包括管部和盖部;The biochemical test tube according to claim 10, characterized by comprising a tube part and a cover part;
    所述管部包括:The tube includes:
    溶液腔;Solution chamber
    试纸固定部件,在所述盖部封闭所述管部的情况下,所述溶液腔的顶部和所述试纸固定部件的顶部连通;A test paper fixing component, where the top of the solution chamber communicates with the top of the test paper fixing component when the cover part closes the tube part;
    若干第一定位部件,若干所述第一定位部件设置于所述溶液腔的底部,用于定位所述破管结构;A plurality of first positioning parts, the plurality of the first positioning parts are arranged at the bottom of the solution chamber for positioning the broken tube structure;
    若干第二定位部件,若干所述第二定位部件设置于若干所述第一定位部件的上部。A plurality of second positioning components are provided on the upper part of the plurality of first positioning components.
  12. 根据权利要求11所述的生化试管,其特征在于,若干所述第一定位部件围绕形成第一腔室;11. The biochemical test tube according to claim 11, wherein a plurality of the first positioning components surround and form a first chamber;
    若干所述第二定位部件围绕形成第二腔室;A plurality of the second positioning components surround to form a second cavity;
    所述第一腔室的轴线与所述第二腔室的轴线共轴。The axis of the first chamber is coaxial with the axis of the second chamber.
  13. 根据权利要求11所述的生化试管,其特征在于,若干所述第一定位部件围绕形成第一腔室;11. The biochemical test tube according to claim 11, wherein a plurality of the first positioning components surround and form a first chamber;
    若干所述第二定位部件围绕形成第二腔室;A plurality of the second positioning components surround to form a second cavity;
    所述第一腔室的轴线与所述第二腔室的轴线的之间的水平距离小于3mm。The horizontal distance between the axis of the first chamber and the axis of the second chamber is less than 3 mm.
  14. 根据权利要求11~13任一所述的生化试管,其特征在于,所述生化试管还包括:The biochemical test tube according to any one of claims 11-13, wherein the biochemical test tube further comprises:
    样品管,所述样品管放置在所述溶液腔,与若干所述第二定位部件配合固定,所述样品管的底部与所述破管结构的尖端和/或刃部接触。A sample tube, the sample tube is placed in the solution chamber, and is fixed in cooperation with a plurality of the second positioning components, and the bottom of the sample tube is in contact with the tip and/or the blade of the tube breaking structure.
  15. 根据权利要求11~14任一所述的生化试管,其特征在于,所述盖部包括:The biochemical test tube according to any one of claims 11-14, wherein the cover part comprises:
    按压部件,所述按压部件设置于所述盖部的内部;A pressing member, the pressing member is arranged inside the cover;
    其中,在所述盖部封闭所述管部的情况下,所述按压部件对准所述管部的所述溶液腔。Wherein, when the cover part closes the tube part, the pressing member is aligned with the solution chamber of the tube part.
  16. 根据权利要求11~15任一所述的生化试管,其特征在于,所述管部还包括:The biochemical test tube according to any one of claims 11-15, wherein the tube part further comprises:
    密封平台,所述密封平台设置在所述溶液腔的顶部的端面,所述密封平台全部地环绕所述溶液腔设置;A sealing platform, the sealing platform is arranged on the end surface of the top of the solution chamber, and the sealing platform is arranged all around the solution chamber;
    在所述盖部封闭所述管部的情况下,所述密封平台与所述盖部的底部具有一定距离。When the cover part closes the tube part, the sealing platform has a certain distance from the bottom of the cover part.
  17. 根据权利要求16所述的生化试管,其特征在于,所述管部还包括:The biochemical test tube according to claim 16, wherein the tube part further comprises:
    密封膜,所述密封膜与所述密封平台连接以密封所述溶液腔。The sealing film is connected with the sealing platform to seal the solution cavity.
  18. 根据权利要求11~17任一所述的生化试管,其特征在于,所述生化试管还包括:The biochemical test tube according to any one of claims 11-17, wherein the biochemical test tube further comprises:
    生化试纸,所述生化试纸设置于所述试纸固定部件的内部;Biochemical test paper, the biochemical test paper is arranged inside the test paper fixing part;
    其中,在所述盖部封闭所述管部的情况下,所述生化试纸的样品溶液接收端靠近所述盖部。Wherein, when the cover part closes the tube part, the sample solution receiving end of the biochemical test paper is close to the cover part.
  19. 根据权利要求18所述的生化试管,其特征在于,所述生化试纸的长度大于所述试纸固定部件的高度。The biochemical test tube according to claim 18, wherein the length of the biochemical test paper is greater than the height of the test paper fixing member.
  20. 根据权利要求11~19任一所述的生化试管,其特征在于,所述生化试管还包括:The biochemical test tube according to any one of claims 11-19, wherein the biochemical test tube further comprises:
    透明中空管,所述生化试纸设置于所述透明中空管的内部,所述透明中空管设置于所述试纸固定部件的内部。A transparent hollow tube, the biochemical test paper is arranged inside the transparent hollow tube, and the transparent hollow tube is arranged inside the test paper fixing member.
  21. 根据权利要求20所述的生化试管,其特征在于,所述透明中空管的一端为封闭端。The biochemical test tube according to claim 20, wherein one end of the transparent hollow tube is a closed end.
  22. 一种导热盲管,应用于如权利要求10~21任一所述的生化试管,其特征在于,所述导热盲管插入所述生化试管,并被位于所述生化试管的底部的所述破管结构破坏。A heat-conducting blind tube applied to the biochemical test tube according to any one of claims 10-21, wherein the heat-conducting blind tube is inserted into the biochemical test tube and is broken by the broken tube at the bottom of the biochemical test tube. The pipe structure is broken.
  23. 根据权利要求22所述的导热盲管,其特征在于,包括:The blind heat conducting tube according to claim 22, characterized in that it comprises:
    盲管体,所述盲管体两端具有开口;A blind tube body with openings at both ends of the blind tube body;
    导热部件,所述导热部件连接于所述盲管体底端开口,且所述导热部件将所述盲管体底端开口密封;A heat-conducting component, the heat-conducting component is connected to the bottom opening of the blind tube body, and the heat-conducting component seals the bottom opening of the blind tube body;
    其中,所述导热部件的导热系数λ>1.0W/(m·K)。Wherein, the thermal conductivity of the thermally conductive component λ>1.0 W/(m·K).
  24. 如权利要求23所述的导热盲管,其特征在于,所述导热部件的材料包括金属。The blind heat conducting tube according to claim 23, wherein the material of the heat conducting component comprises metal.
  25. 如权利要求23或24所述的导热盲管,其特征在于,所述导热部件的材料包括导热塑料, 且导热塑料的导热系数λ>1.0W/(m·K)。The heat-conducting blind tube according to claim 23 or 24, wherein the material of the heat-conducting component comprises a heat-conducting plastic, and the thermal conductivity of the heat-conducting plastic is λ>1.0 W/(m·K).
  26. 如权利要求23~25任一所述的导热盲管,其特征在于,所述导热部件包括导热块,所述导热块与所述盲管体嵌合连接。The heat-conducting blind pipe according to any one of claims 23-25, wherein the heat-conducting component comprises a heat-conducting block, and the heat-conducting block is fitted and connected with the blind pipe body.
  27. 如权利要求26所述的导热盲管,其特征在于,所述导热块上设置有第四嵌合部件。The heat-conducting blind tube according to claim 26, wherein a fourth fitting part is provided on the heat-conducting block.
  28. 如权利要求27所述的导热盲管,其特征在于,所述第四嵌合部件包括设置于所述导热块上的凸环以及设置于所述盲管体上与所述凸环配合连接的凹槽。The heat-conducting blind tube according to claim 27, wherein the fourth fitting part comprises a convex ring arranged on the heat-conducting block and a convex ring arranged on the blind tube body and connected with the convex ring in a mating manner. Groove.
  29. 如权利要求28所述的导热盲管,其特征在于,所述凸环设置有两个。The blind heat conducting tube according to claim 28, wherein two convex rings are provided.
  30. 如权利要求23~29任一所述的导热盲管,其特征在于,还包括盲管盖,所述盲管盖与所述盲管体为一体成型结构。The thermally conductive blind tube according to any one of claims 23-29, further comprising a blind tube cover, and the blind tube cover and the blind tube body are integrally formed.
PCT/CN2021/101111 2020-06-19 2021-06-19 Tube-breaking structure, biochemical test tube and heat-conducting blind tube WO2021254512A1 (en)

Applications Claiming Priority (10)

Application Number Priority Date Filing Date Title
CN202021152906.2 2020-06-19
CN202010569184.9 2020-06-19
CN202010569184 2020-06-19
CN202021152906 2020-06-19
CN202120200347.6U CN214278192U (en) 2021-01-25 2021-01-25 Broken tubular construction and biochemical test tube
CN202110097129.9 2021-01-25
CN202110097129.9A CN112858658B (en) 2021-01-25 2021-01-25 Broken tube structure and biochemical test tube
CN202120200347.6 2021-01-25
CN202110194027.9A CN114958562A (en) 2021-02-20 2021-02-20 Heat conduction blind pipe
CN202110194027.9 2021-02-20

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KR20100002115U (en) * 2008-08-19 2010-03-02 정준채 Molding device of drain hole for flexible waterway
CN102876569A (en) * 2011-07-11 2013-01-16 瑞基海洋生物科技股份有限公司 Capillary tube for heat convection polymerase chain reaction device
CN205574438U (en) * 2016-03-14 2016-09-14 上海快灵生物科技有限公司 Broken leakproofness test tube subassembly of managing mechanism and including this broken pipe mechanism
CN206476995U (en) * 2016-06-13 2017-09-08 秦荣 A kind of PCR test tubes
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