CN207717440U - Sterile sampling interface arrangement - Google Patents
Sterile sampling interface arrangement Download PDFInfo
- Publication number
- CN207717440U CN207717440U CN201820175312.XU CN201820175312U CN207717440U CN 207717440 U CN207717440 U CN 207717440U CN 201820175312 U CN201820175312 U CN 201820175312U CN 207717440 U CN207717440 U CN 207717440U
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- China
- Prior art keywords
- rubber plug
- mounting flange
- end cap
- probe tube
- seal gasket
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- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
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- Investigating Or Analysing Biological Materials (AREA)
Abstract
A kind of sterile sampling interface arrangement, including supervisor and probe tube；One end of the probe tube is connected with the side wall of supervisor, to make supervisor be connected with probe tube；The other end of the probe tube is provided with mounting flange, and the rubber plug that syringe needle can be made to pierce through is equipped on its port；The seal gasket of annular is installed, the rubber plug is located at the center of seal gasket on the surface of the mounting flange；End cap and clip are installed, the clip side clamps end cap, and the other side clamps mounting flange, to make end cap that the flange and seal gasket that rubber plug side wall is arranged to be pressed on the surface of mounting flange on the mounting flange；Sample tap is provided on the end cap, the sample tap is aligned with end cap；The internal diameter of the sample tap is less than the outer diameter of the rubber plug.The rubber plug that sterile sampling interface arrangement is equipped with makes syringe needle can pierce rubber plug, penetrates in probe tube, easy to operate using the direct pipette samples of syringe, is protected without using flame, avoids causing high-temperature sample rotten, to ensure that the accuracy of detection.
Description
Technical field
The utility model belongs to biological medicine apparatus field more particularly to a kind of sterile sampling interface arrangement.
Background technology
The various pieces of current production of vaccine equipment, automatic operating, equipment are connected by pipeline, in order to ensure final
The product quality produced is met the requirements, and needs to carry out Sterility testing to the semi-finished product in production process.Since semi-finished product are in pipe
It is flowed in road, in order to which semi-finished product taking-up to be detected, sample connection device is set on pipeline.
The sample connection device being arranged on pipeline at present, valvular probe tube is installed to be connected on pipeline, is sampled
When open valve, so that semi-finished product is flowed out from probe tube, due to needing double of city product to carry out Sterility testing, in order to avoid causing dirt
Dye, and need to carry out flame protection to the port of probe tube, operates fairly cumbersome, and flame also can to the half of outflow at
Product cause to toast, and make semi-finished product modification at high temperature, influence the precision of testing result.
Utility model content
The utility model is directed to above-mentioned existing sample connection device, proposes a kind of easy to operate and energy
Enough ensure the sterile sampling interface arrangement of accuracy of detection.
In order to achieve the above object, the technical solution adopted in the utility model is：
A kind of sterile sampling interface arrangement, including supervisor and probe tube；The side wall phase of one end of the probe tube and supervisor
Even, to make supervisor be connected with probe tube；The other end of the probe tube is provided with mounting flange, and is installed on its port
There is the rubber plug that syringe needle can be made to pierce through；
The seal gasket of annular is installed, the rubber plug is located at the center of seal gasket on the surface of the mounting flange；
End cap and clip are installed, the clip side clamps end cap, and the other side clamps Method for Installation on the mounting flange
Orchid, to make end cap that the flange and seal gasket that rubber plug side wall is arranged to be pressed on the surface of mounting flange；
Sample tap is provided on the end cap, the sample tap is aligned with end cap；
The internal diameter of the sample tap is less than the outer diameter of the rubber plug.
Preferably, being provided with annular protrusion on the surface of the mounting flange, the annular protrusion connects with seal gasket
It touches, and is coaxially aligned.
Preferably, being provided with accommodating chamber in the rubber plug, the disinfection that syringe needle passes through can be made by being filled in the accommodating chamber
Cotton.
Preferably, the accommodating chamber is located at the outside of rubber plug, the accommodating chamber inside side walls and rubber plug inner end end face it
Between distance be more than the accommodating chamber thickness.
Compared with prior art, it is with good effect the advantages of the utility model：
1, the rubber plug that sterile sampling interface arrangement is equipped with makes syringe needle can pierce rubber plug, penetrates in probe tube, utilizes note
The direct pipette samples of emitter, it is easy to operate, it is protected without using flame, avoids causing high-temperature sample rotten, to ensure
The accuracy of detection.
2, the port of probe tube is sealed by rubber plug and seal gasket, forms two layers of sealing structure, ensure that sealing
Effect avoids liquid in pipe from leaking out.Mounting flange surface setting protrusion, increase seal gasket contact close with mounting flange
Property, improve sealing effect.
3, aseptic cotton is set in rubber plug, to across syringe needle carry out disinfection, avoid the bacterium being adhered on syringe needle from entering
It in probe tube, pollutes, and then influences the quality of vaccine product.The thickness of inner segment is larger, the rubber structure for making syringe needle pierce through
With enough thickness and structural strength, avoids puncturing rubber plug, liquid is avoided to leak out.
Description of the drawings
Fig. 1 is the sectional structure chart of sterile sampling interface；
In above each figure：1, it is responsible for；2, probe tube；3, mounting flange；3.1, annular protrusion；4, rubber plug；4.1, flange；
4.2, accommodating chamber；5, seal gasket；6, end cap；6.1, sample tap；7, clip；8, aseptic cotton；.
Specific implementation mode
In the following, the utility model is specifically described by illustrative embodiment.It should be appreciated, however, that not having
In the case of being further discussed below, element, structure and features in an embodiment can also be advantageously incorporated into other implementations
In mode.
In the description of the present invention, it should be noted that term "inner", "outside", "upper", "lower", "front", "rear" etc.
The orientation or positional relationship of instruction is position relationship based on ... shown in the drawings, is merely for convenience of description the utility model and simplification
Description, does not indicate or imply the indicated device or element must have a particular orientation, with specific azimuth configuration and behaviour
Make, therefore should not be understood as limiting the present invention.In addition, term " first ", " second ", " third " are only used for description mesh
, it is not understood to indicate or imply relative importance.
As shown in Figure 1, sterile sampling interface arrangement includes supervisor 1 and probe tube 2.Be responsible for 1 both ends respectively with production equipment
It is connected, semi-finished product liquid is made to flow through supervisor 1 during production.
One end of probe tube 2 is connected with the side wall of supervisor 1, to make supervisor 1 be connected with probe tube 2, will flow through
The semi-finished product liquid of supervisor 1 is drawn out in probe tube 2.
The other end of probe tube 2 is provided with mounting flange 3, and rubber plug 4 is installed on its port, and rubber plug 4 is by 2 end of probe tube
Mouth sealing, avoids the semi-finished product liquid being drawn out in probe tube 2 from leaking out.
The seal gasket 5 of annular is installed, rubber plug 4 is located at the center of seal gasket 5 on the surface of mounting flange 3.Installation
End cap 6 and clip 7 are installed, 7 side of clip clamps end cap 6, and the other side clamps mounting flange 3, will by clip 7 on flange 3
End cap 6 is fixed on mounting flange 3, while also fixing the spacing between end cap 6 and mounting flange 3, makes end cap 6 by rubber plug 4
The flange 4.1 and seal gasket 5 of side wall setting are pressed on the surface of mounting flange 3.
Rubber plug 4 and seal gasket 5 from inside to outside, form two layers of sealing structure, avoid in probe tube 2 radially
Semi-finished product liquid leaks out.
Sample tap 6.1 is provided on end cap 6, sample tap 6.1 is aligned with end cap 6, makes the end face leakage in 6 outside of end cap.It takes
The internal diameter of sample mouth 6.1 is less than the outer diameter of rubber plug 4, makes rubber plug 4 that can not pass through sample tap 6.1, and the edge of sample tap 6.1 is pressed
On end cap 6, end cap 6 is enable to be completely fixed, ensures leakproofness.
When sampling, using the syringe for being mounted with syringe needle, by syringe needle by sample tap 6.1, axially penetrates and pass through rubber plug
4, so that syringe needle is entered in probe tube across rubber plug 4, and then syringe is enable to extract the semi-finished product liquid in probe tube 1, into
Row sampling.
After the completion of sampling, syringe needle is extracted out from rubber plug 4.Since rubber plug 4 is made of propionitrile, when syringe needle pierces through rubber plug 4,
Syringe needle side wall pushes rubber plug 4 outward；After syringe needle extracts rubber plug 4 out, rubber plug 4 can resile, and the position that syringe needle pierces through is closed
It closes, liquid is avoided to leak out, while realizing that needle adopts sample, can ensure leakproofness, can repeat to sample, have enough
Service life.
In order to improve the sealing performance of seal gasket 5, annular protrusion 3.1, convex annular are provided on the surface of mounting flange 3
It plays 3.1 to contact with seal gasket 5, and is coaxially aligned.
Annular protrusion 3.1 further reduces the spacing between end cap 6 and mounting flange 3, increases seal gasket 5 and is squeezed
The degree of pressure, improves leakproofness.
In order to avoid polluting, it is provided with accommodating chamber 4.2 in rubber plug 4, aseptic cotton 8, disinfection are filled in accommodating chamber 4.2
Cotton 8, which absorbs, disinfectant.
When being sampled, syringe needle is pierced into rubber plug 4, enters in accommodating chamber 4.1, and pierce through aseptic cotton 8, is then being pierced by appearance
It receives chamber 4.1, pierces through rubber plug 4, enter in probe tube 2.During syringe needle is pierced into, contact sterilizing cotton 8 makes aseptic cotton 8 to needle
The outer wall of head is wiped, and is carried out disinfection, is prevented the bacterium being adhered on syringe needle outer wall, enters therewith in probe tube 2, is polluted
Semi-finished product liquid, and then the entire production line is polluted, it prevents from therefore causing economic loss, ensures product quality.
In order to ensure that the whole structural strength of rubber plug 4, accommodating chamber 4.2 are located at the outside of rubber plug 4, syringe needle is made to pierce through rubber plug 4
When, accommodating chamber 4.2 is initially passed through, the inside of rubber plug 4 is then passed through.
The distance between 4.2 inside side walls of accommodating chamber and 4 inner end end face of rubber plug are more than the thickness for stating accommodating chamber 4.2, make glue
The inner thickness of plug 4 is more than accommodating chamber 4.2, keeps the space that accommodating chamber 4.2 occupies in rubber plug 4 smaller, will not be whole to rubber plug 4
Intensity impacts.Ensure that the part that syringe needle pierces through, rubber part have certain thickness, can resile close again simultaneously
Envelope avoids the partial rubber that syringe needle pierces through relatively thin, will be punctured inside rubber plug 4, to ensure the leakproofness of rubber plug 4, ensures sampling
Repeatable operation, rubber plug 4 have enough service life.
Claims (4)
1. a kind of sterile sampling interface arrangement, which is characterized in that including supervisor (1) and probe tube (2)；One end of the probe tube
It is connected with the side wall of supervisor (1), to make supervisor (1) be connected with probe tube (2)；The other end of the probe tube (2) is arranged
There is mounting flange (3), and the rubber plug (4) that syringe needle can be made to pierce through is installed on its port；
The seal gasket (5) of annular is installed, the rubber plug (4) is located at seal gasket (5) on the surface of the mounting flange (3)
Center；
End cap (6) and clip (7) are installed, clip (7) side clamps end cap (6), the other side on the mounting flange (3)
Mounting flange (3) is clamped, the flange (4.1) and seal gasket (5) to make end cap (6) that rubber plug (4) side wall to be arranged compress
On the surface of mounting flange (3)；
Sample tap (6.1) is provided on the end cap (6), the sample tap (6.1) is aligned with end cap (6)；
The internal diameter of the sample tap (6.1) is less than the outer diameter of the rubber plug (4).
2. sterile sampling interface arrangement according to claim 1, which is characterized in that on the surface of the mounting flange (3)
It is provided with annular protrusion (3.1), the annular protrusion (3.1) contacts with seal gasket (5), and is coaxially aligned.
3. sterile sampling interface arrangement according to claim 1, which is characterized in that be provided with receiving in the rubber plug (4)
Chamber (4.2), filled with the aseptic cotton (8) that syringe needle passes through can be made in the accommodating chamber (4.2).
4. sterile sampling interface arrangement according to claim 3, which is characterized in that the accommodating chamber (4.2) is located at rubber plug
(4) outside, the distance between accommodating chamber (4.2) inside side walls and rubber plug (4) inner end end face are more than the accommodating chamber
(4.2) thickness.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201820175312.XU CN207717440U (en) | 2018-01-31 | 2018-01-31 | Sterile sampling interface arrangement |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201820175312.XU CN207717440U (en) | 2018-01-31 | 2018-01-31 | Sterile sampling interface arrangement |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CN207717440U true CN207717440U (en) | 2018-08-10 |
Family
ID=63053256
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN201820175312.XU Active CN207717440U (en) | 2018-01-31 | 2018-01-31 | Sterile sampling interface arrangement |
Country Status (1)
| Country | Link |
|---|---|
| CN (1) | CN207717440U (en) |
Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN109398924A (en) * | 2018-10-12 | 2019-03-01 | 吴迪 | A kind of bottled sterile solution adding set |
| CN109515961A (en) * | 2018-10-12 | 2019-03-26 | 吴迪 | A kind of sterile solution adding set |
-
2018
- 2018-01-31 CN CN201820175312.XU patent/CN207717440U/en active Active
Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN109398924A (en) * | 2018-10-12 | 2019-03-01 | 吴迪 | A kind of bottled sterile solution adding set |
| CN109515961A (en) * | 2018-10-12 | 2019-03-26 | 吴迪 | A kind of sterile solution adding set |
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