Classifications

• • A—HUMAN NECESSITIES
  • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
  • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
  • A61K8/00—Cosmetics or similar toiletry preparations
  • A61K8/02—Cosmetics or similar toiletry preparations characterised by special physical form
  • A61K8/04—Dispersions; Emulsions
  • A61K8/06—Emulsions
  • A61K8/062—Oil-in-water emulsions
• • A—HUMAN NECESSITIES
  • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
  • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
  • A61K8/00—Cosmetics or similar toiletry preparations
  • A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
  • A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
  • A61K8/33—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing oxygen
  • A61K8/34—Alcohols
  • A61K8/345—Alcohols containing more than one hydroxy group
• • A—HUMAN NECESSITIES
  • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
  • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
  • A61K8/00—Cosmetics or similar toiletry preparations
  • A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
  • A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
  • A61K8/40—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing nitrogen
  • A61K8/44—Aminocarboxylic acids or derivatives thereof, e.g. aminocarboxylic acids containing sulfur; Salts; Esters or N-acylated derivatives thereof
• • A—HUMAN NECESSITIES
  • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
  • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
  • A61K8/00—Cosmetics or similar toiletry preparations
  • A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
  • A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
  • A61K8/67—Vitamins
• • A—HUMAN NECESSITIES
  • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
  • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
  • A61K8/00—Cosmetics or similar toiletry preparations
  • A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
  • A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
  • A61K8/67—Vitamins
  • A61K8/673—Vitamin B group
  • A61K8/675—Vitamin B3 or vitamin B3 active, e.g. nicotinamide, nicotinic acid, nicotinyl aldehyde
• • A—HUMAN NECESSITIES
  • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
  • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
  • A61K8/00—Cosmetics or similar toiletry preparations
  • A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
  • A61K8/72—Cosmetics or similar toiletry preparations characterised by the composition containing organic macromolecular compounds
  • A61K8/73—Polysaccharides
• • A—HUMAN NECESSITIES
  • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
  • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
  • A61K8/00—Cosmetics or similar toiletry preparations
  • A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
  • A61K8/72—Cosmetics or similar toiletry preparations characterised by the composition containing organic macromolecular compounds
  • A61K8/81—Cosmetics or similar toiletry preparations characterised by the composition containing organic macromolecular compounds obtained by reactions involving only carbon-to-carbon unsaturated bonds
• • A—HUMAN NECESSITIES
  • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
  • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
  • A61K8/00—Cosmetics or similar toiletry preparations
  • A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
  • A61K8/72—Cosmetics or similar toiletry preparations characterised by the composition containing organic macromolecular compounds
  • A61K8/84—Cosmetics or similar toiletry preparations characterised by the composition containing organic macromolecular compounds obtained by reactions otherwise than those involving only carbon-carbon unsaturated bonds
  • A61K8/86—Polyethers
• • A—HUMAN NECESSITIES
  • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
  • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
  • A61K8/00—Cosmetics or similar toiletry preparations
  • A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
  • A61K8/72—Cosmetics or similar toiletry preparations characterised by the composition containing organic macromolecular compounds
  • A61K8/84—Cosmetics or similar toiletry preparations characterised by the composition containing organic macromolecular compounds obtained by reactions otherwise than those involving only carbon-carbon unsaturated bonds
  • A61K8/89—Polysiloxanes
• • A—HUMAN NECESSITIES
  • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
  • A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
  • A61Q19/00—Preparations for care of the skin
• • A—HUMAN NECESSITIES
  • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
  • A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
  • A61Q19/00—Preparations for care of the skin
  • A61Q19/08—Anti-ageing preparations

Definitions

• the present invention relates to an oil-in-water emulsified cosmetic.
• the skin causes pigmentation such as wrinkles, sagging, stains and freckles due to internal factors such as aging and stress, and external factors such as ultraviolet rays and dry air.
• pigmentation such as wrinkles, sagging, stains and freckles due to internal factors such as aging and stress, and external factors such as ultraviolet rays and dry air.
• morphological changes such as wrinkles and sagging and visual changes such as pigmentation greatly affect the impression of appearance, so many people want to improve them, and various products are offered.
• niacinamide which is an active ingredient of wrinkles and sagging
• tranexamic acid as a whitening agent for improving or suppressing pigmentation
• the present invention relates to niacinamide and / or tranexamic acid, silicone oil, one or more selected from polyoxyalkylene-added glycerin derivatives represented by a specific formula, and oil in water using an amphipathic polymer. It is an object of the present invention to provide an oil-in-water emulsified cosmetic having an excellent permeation feeling and a long-lasting moisturizing feeling.
• the present inventor added silicone oil and a polyoxyalkylene represented by a specific formula in an oil-in-water emulsified cosmetic containing the active ingredients niacinamide and / or tranexamic acid. It has been found that the above-mentioned problems can be solved by containing one or more kinds selected from glycerin derivatives and an amphipathic polymer, and the present invention has been completed.
• the present invention is an oil-in-water emulsified cosmetic containing wrinkles, sagging, and whitening active ingredients, which is excellent not only in moisturizing immediately after application but also in maintaining and penetrating the moisturizing feeling.
• An oil-in-water emulsified cosmetic containing the following components (A) to (D). [1] The following components (A) to (D); (A) Niacinamide and / or tranexamic acid 1-10% by mass (B) Silicone oil (C) One or more glycerin derivatives selected from the component (c1) and the component (c2) represented by the following general formula Component (c1) General formula (1) ...
• Gly is a residue obtained by removing a hydroxyl group from glycerin
• PO is an oxypropylene group
• EO is an oxyethylene group
• l and m are the average number of moles of PO and EO, respectively, and (l + m).
• the mass ratio (PO / EO) is 1/5 to 5/1
• BO is an oxyalkylene group having 4 carbon atoms
• n is the average number of moles of BO added.
• Component (c2) General formula (2) ...
• R represents ⁇ [CH2CH (CH3) O] ⁇ , p, q, r, and s each represent an integer of 0 to 20, and p + q + r + s represents an integer of 4 to 20.
• (D) Amphiphilic polymer It is an oil-in-water emulsified cosmetic containing. [2] The component (D) is an acrylic acid / alkyl methacrylate copolymer, acryloyldimethyltaurine ammonium / vinylpyrrolidone copolymer, acryloyldimethyltaurinammonium methacrylate behenes-25 copolymer, hydroxyethyl acrylate / acryloyldimethyl.
• [7] The water according to any one of [1] to [6], wherein the content mass ratio (A) / [(B) + (C)] of the components (A) to (C) is 0.05 or more and less than 7. It is an oil-type emulsified cosmetic. [8] Any of [1] to [7], wherein the content mass ratio [(B) + (C) + (D)] / (A) of the components (A) to (D) is 0.1 or more and 20 or less.
• the oil-in-water emulsified cosmetic of the present invention has an excellent permeation feeling, but also has an excellent moisturizing feeling immediately after application and a long-lasting moisturizing feeling. Further, the oil-in-water emulsified cosmetic of the present invention is not sticky after use and can give a good feeling of use.
• X to Y indicating a range includes X and Y and means "X or more and Y or less”.
• operations and physical properties are measured under the conditions of room temperature (25 ° C.) / relative humidity of 40% RH.
• niacinamide used in the present invention is an amide compound of nicotinic acid (vitamin B3 / niacin).
• Niacinamide is a water-soluble vitamin, a known substance that is one of the B vitamins, and can be extracted from natural products (rice bran, etc.) or synthesized by a known method. Specifically, those listed in the 17th revised Japanese Pharmacopoeia can be used.
• the component (A) tranexamic acid used in the present invention is a kind of amino acid represented by the chemical name: trans-4- (aminomethyl) cyclohexane-1-carboxylic acid, and as described above, it has a whitening effect and anti-skin effect on the skin. In addition to being known as a component having an inflammatory effect, it may also be used as a hemostatic agent.
• the content of the component (A) in the present invention is 1% by mass (hereinafter, simply “mass%” is abbreviated as “%") or more in the oil-in-water emulsified cosmetic from the viewpoint of the effect of the active ingredient and the like. It is preferably 2% or more, and even more preferably 5% or more.
• the content of the component (A) is preferably 10% or less, more preferably 8% or less, and even more preferably 7% or less. If the content of the component (A) is less than 1%, a satisfactory effect of the active ingredient may not be obtained, and if it exceeds 10%, the stickiness at the time of application is strong and the usability is poor. There is.
• the component (A) niacinamide and tranexamic acid can be used alone or in combination, and two kinds can be used in combination from the viewpoint of excellent action as an active ingredient such as skin anti-aging effect and whitening effect. preferable.
• the content of the component (A) niacinamide is preferably 1% or more, more preferably 2% or more in the oil-in-water emulsified cosmetic from the viewpoint of action as an active ingredient. It is preferably 3% or more, more preferably 4% or more, and particularly preferably 4% or more.
• the content of the component (A) tranexamic acid is preferably 1% or more, more preferably 1.5% or more in the oil-in-water emulsified cosmetic from the viewpoint of action as an active ingredient. It is preferably 2% or more, and even more preferably 2% or more. Further, it is preferably less than 10%, more preferably 5% or less, and even more preferably 3% or less from the viewpoint of usability such as non-stickiness.
• the silicone oil of the component (B) used in the present invention is not particularly limited as long as it is usually used for cosmetics.
• the properties of the silicone oil are not particularly limited, but it is more preferable that the silicone oil is liquid at 25 ° C. from the viewpoint of excellent usability.
• these silicone oils include dimethicone, methylphenylpolysiloxane, octamethylcyclotetrasiloxane, decamethylcyclopentasiloxane, methyltrimethicone, polyether-modified methylpolysiloxane, oleyl-modified methylpolysiloxane, polyvinylpyrrolidone-modified methylpolysiloxane, and octa.
• Examples thereof include methylcyclotetrasiloxane, dodecamethylcyclohexasiloxane, hexamethyldisiloxane, octamethyltrisiloxane, decamethyltetrasiloxane, caprylyltrimethicone, methylphenylpolysiloxane, dimethiconol, etc., and one or more of these. Can be appropriately selected and used. In the present invention, it is preferable to use methylphenylpolysiloxane and / or dimethicone, and it is more preferable to use dimethicone because the permeation feeling and the moisturizing feeling are remarkably maintained.
• the viscosity of dimethicone used in the present invention is not particularly limited, but from the viewpoint of permeation, the viscosity at 25 ° C. is preferably 1 to 200 mPa ⁇ s, more preferably 2 to 100 mPa ⁇ s.
• the viscosity of the component (B) is measured according to the second method of the cosmetic raw material standard / viscosity measurement method using a Brookfield type viscometer.
• the component (B) is contained in an amount of 60% or more based on the total amount of the oil contained in the oil-in-water emulsified cosmetic, it is excellent in non-stickiness, penetration and moisturizing feeling.
• An oil-in-water emulsified cosmetic can be obtained.
• the component (B) is 60% or more in the total amount of the oil agent contained in the oil-in-water emulsified cosmetic.
• the content of the component (B) in the total amount of the oil agent contained in the oil-in-water emulsified cosmetic is 60% or more, 70% or more, 80% or more, 85% or more, 90% or more in the preferable order.
• the upper limit of the content of the component (B) in the total amount of the oil agent contained in the oil-in-water emulsified cosmetic is 100%.
• oil agent other than the component (B) examples include hydrocarbons such as isododecane, isohexadecane, light isoparaffin, liquid paraffin, squalane, squalane, ⁇ -olefin oligomer, polybutene, liquid isoparaffin, heavy liquid isoparaffin, polyisobutylene, and hydrogenated polyisobutene.
• hydrocarbons such as isododecane, isohexadecane, light isoparaffin, liquid paraffin, squalane, squalane, ⁇ -olefin oligomer, polybutene, liquid isoparaffin, heavy liquid isoparaffin, polyisobutylene, and hydrogenated polyisobutene.
• Oils Oils; fatty acids such as oleic acid and isostearic acid; higher alcohols such as oleyl alcohol, 2-octyldodecanol, 2-decyltetradecanol, isostearyl alcohol, 2-hexyldecanol; perfluoropolyether, perfluorodecane, Fluorine oils such as perfluorooctane; lanolin derivatives such as lanolin acetate, lanolin fatty acid isopropyl, lanolin alcohol; glyceryl tri2-ethylhexanoate, glyceryl diisostearate, diglyceryl diisostearate, glyceryl triisostearate, triisostearic acid Diglyceryl, trimethylolpropane triisostearate, diglyceryl tetraisostearate, polyglyceryl decaisostearate, isotridecyl isononanoate, pent
• the content of the total amount of the oil agent composed of the above-mentioned component (B) and the oil agent other than the above-mentioned component (B) is not particularly limited, but from the viewpoint of non-stickiness and maintenance of moisturizing feeling, etc. It is preferably 0.2% or more, more preferably 0.5% or more, and further preferably 1% or more in the oil-in-water emulsified cosmetic. Further, the content of the total amount of the oil agent composed of the above component (B) and the oil agent other than the above component (B) is 20% or less in the oil-in-water emulsified cosmetic from the viewpoint of permeation feeling and moisturizing feeling immediately after application. It is preferably 10% or less, and further preferably 7% or less.
• the content of the hydrocarbon oil is as low as possible.
• the content of the hydrocarbon oil should be less than 1% in the oil-in-water emulsified cosmetic. Is preferable, 0.5% or less is more preferable, and it is preferably not contained (0%).
• the content of the component (B) silicone oil in the present invention is not particularly limited, but is preferably 0.1% or more in the oil-in-water emulsified cosmetic from the viewpoint of maintaining a moisturizing feeling. , 0.5% or more is more preferable. Further, the content of the component (B) is preferably 10% or less, more preferably 5% or less in the oil-in-water emulsified cosmetic from the viewpoint of reducing stickiness and penetrating feeling.
• Component (C) One or more glycerin derivatives selected from (c1) and (c2) represented by the following general formula)
• the component (C) used in the present invention is one or more glycerin derivatives selected from the component (c1) and the component (c2) represented by the following general formula.
• Component (c1) General formula (1) ...
• Gly is a residue obtained by removing a hydroxyl group from glycerin
• PO is an oxypropylene group
• EO is an oxyethylene group
• l and m are the average number of moles of PO and EO, respectively, and (l + m).
• the mass ratio (PO / EO) is 1/5 to 5/1
• BO is an oxyalkylene group having 4 carbon atoms
• n is the average number of moles of BO added.
• the component (c1) is glycerin supplemented with propylene oxide and ethylene oxide in a total ratio of 3 to 180 molar equivalents with respect to glycerin, or alkylene oxide having 4 carbon atoms is further added with 0 to 15 mol with respect to glycerin. It is added at the ratio of equivalent amount.
• the glycerin derivative of the component (c1) can be obtained by synthesizing an adduct of PO and EO once and then adding an alkylene oxide having 4 carbon atoms in a block form.
• the mass ratio (PO / EO) of propylene oxide (PO) and ethylene oxide (EO) of the component (c1) is 1/5 to 5/1, and the addition form of propylene oxide and ethylene oxide may be random or block. good.
• the mass ratio (PO / EO) of propylene oxide (PO) and ethylene oxide (EO) is less than 1/5, the permeation feeling, the moisturizing feeling immediately after application, and the sustainability of the moisturizing feeling decrease and exceed 5/1. Has less stickiness and less penetration.
• the average number of moles of propylene oxide (PO) and ethylene oxide (EO) added to the component (c1) is preferably 3 to 180 mol in total, that is, l + m is preferably in the range of 1 to 60, and the feeling of penetration, moisturizing, etc. From the viewpoint, it is more preferable that the average number of added moles of PO and EO is 3 to 150 mol in total, that is, l + m is in the range of 1 to 50, and the average number of added moles of PO and EO is 3 to 90 mol in total, that is, l + m. It is more preferably in the range of 1 to 30.
• the average number of added moles of PO and EO is less than 3 moles in total, that is, l + m is less than 1, the non-stickiness and the feeling of penetration may not be excellent.
• the average number of added moles is 180 moles in total, that is, when l + m exceeds 60, the moisturizing sensation immediately afterwards and the sustainability of the moisturizing sensation may not be excellent.
• the average number of moles of propylene oxide (PO) added to the component (c1) is preferably 3 to 90 mol, that is, l is in the range of 1 to 30, and the average number of moles of PO added is 3 to 60. That is, it is more preferable that l is in the range of 1 to 20. Within this range, the effects of the present invention such as non-stickiness, permeation feeling, moisturizing feeling immediately after application and maintenance of moisturizing feeling are more preferably exhibited, which is preferable.
• the average number of moles of alkylene oxide (BO) having 4 carbon atoms in the component (c1) is preferably 0 to 15, that is, n is in the range of 0 to 5, and the average number of moles of BO added is 3 to 5. More preferably, 15 mol, i.e. n is in the range of 1-5. When the average number of added moles of BO exceeds 15, that is, n exceeds 5, the non-stickiness and the feeling of penetration may not be excellent.
• the total number of moles of propylene oxide (PO) and ethylene oxide (EO) added is 90 to 180 in total.
• the moles, i.e. l + m, are preferably in the range of 30-60, and the average number of added moles of PO and EO is more preferably 90-150 mol, i.e. l + m in the range of 30-50.
• the average number of added moles of BO is 1 to 5, that is, n is in the range of 1 to 5
• the average number of added moles of PO and EO is 3 to 90 mol in total, that is, l + m is in the range of 1 to 30. It is preferable that the average number of added moles of PO and EO is 3 to 60 mol in total, that is, l + m is in the range of 1 to 20.
• the effects of the present invention such as non-stickiness, permeation feeling, moisturizing feeling immediately after application and maintenance of moisturizing feeling are more preferably exhibited, which is preferable.
• alkylene oxide having 4 carbon atoms of the component (c1) examples include 1,2-butylene oxide, 2,3-butylene oxide, and tetramethylene oxide (tetrahydrofuran).
• 1,2-butylene oxide is preferable from the viewpoint of easy availability, easy reaction control, and the like.
• the component (c1) is polyoxybutylene poly having an average number of moles of (EO) of 8, an average number of moles of (PO) of 5, and an average number of moles of (BO) of 3.
• 24EO) (24PO) is preferable because it improves the permeation feeling, the moisturizing feeling immediately after application, and the sustainability of the moisturizing feeling.
• polyoxyethylene (24) polyoxypropylene (24) glyceryl ether (trade name: NIKKOL SG-G2424, manufactured by Nikko Chemicals Co., Ltd.), polyoxybutylene (3) polyoxyethylene (8) poly.
• examples thereof include oxypropylene (5) glyceryl ether (trade name: Wilbride S-753, manufactured by NOF CORPORATION). One or more of these can be used.
• the component (c2) of the present invention can be obtained by adding propylene oxide to diglycerin by a conventional method.
• the number of moles of propylene oxide added is preferably 4 to 20 mol, more preferably 5 to 15 mol, and further 8 to 15 mol per molecule of diglycerin from the viewpoint of non-stickiness, permeation feeling, moisturizing feeling, and the like.
• 8 to 10 are even more preferable.
• polyoxypropylene diglyceryl (9PO) having an average addition molar number of (PO) of 9 improves the permeation feeling, the moisturizing feeling immediately after application, and the sustainability of the moisturizing feeling. Therefore, it is preferable.
• these commercially available products include polyoxypropylene (9) diglyceryl (trade name: SY-DP9, manufactured by Sakamoto Yakuhin Kogyo Co., Ltd.). One or more of these can be used.
• glycerin derivatives of the above-mentioned components (c1) and (c2) when alkylene oxide is added to glycerin or diglycerin, an addition reaction is carried out using an alkali catalyst, a phase transfer catalyst, a Lewis acid catalyst or the like. Generally, it is preferable to use an alkaline catalyst such as potassium hydroxide.
• the component (C) can contain one or more selected from the component (c1) and the component (c2).
• the component (C) is the component (c1) from the viewpoint that the effect of sustaining the moisturizing feeling is more preferably exhibited.
• the inclusion of two types of the component (C) may be any combination of two types of the component (c1), two types of the component (c2), and the component (c1) and the component (c2).
• the content of the component (C) of the present invention is not particularly limited, but is preferably 1% or more in the oil-in-water emulsified cosmetic from the viewpoint of non-stickiness, permeation, and the like. % Or more is more preferable, and 3% or more is even more preferable. Further, the content of the component (C) is more preferably 20% or less, and preferably 15% or less, preferably 10% or less, from the viewpoint of the moisturizing feeling immediately after application and the maintenance of the moisturizing feeling. Is even more preferable.
• the content mass ratio (A) / [(B) + (C)] of the components (A) to (C) is not particularly limited, but is preferably 0.05 or more, and 0. It is more preferably 1 or more, further preferably 0.2 or more, and particularly preferably 0.3 or more, from the viewpoint of non-stickiness, penetration feeling and the like. Further, the content mass ratio (A) / [(B) + (C)] is preferably less than 7, preferably 5 or less, from the viewpoint of the moisturizing feeling immediately after application and the maintenance of the moisturizing feeling. It is more preferably 3.5 or less, and particularly preferably 2.5 or less.
• the component (D) amphipathic polymer used in the present invention is stable in cosmetics and compositions by itself without a surfactant or by adding a small amount even if a surfactant is used in combination.
• a polymer compound that can be an oil-in-water emulsified dispersion For example, acrylic acid / alkyl methacrylate copolymer, acryloyldimethyltaurine ammonium / vinylpyrrolidone copolymer, acryloyldimethyltaurinammonium methacrylate behenes-25 copolymer, hydroxyethyl acrylate / acryloyldimethyltaurine Na copolymer.
• a butyl methacrylate copolymer can be mentioned, and at least one of these components can be used.
• the component (D) is an acrylic acid / alkyl methacrylate copolymer, an acryloyldimethyltaurine ammonium / vinylpyrrolidone copolymer, and an acryloyldimethyltaurin ammonium methacrylate polymer from the viewpoint of maintaining a feeling of penetration and moisturizing. It is preferable to use a Hennes-25 copolymer, a hydroxyethyl acrylate / acryloyldimethyltaurine Na copolymer, a Na acrylate / Na acryloyldimethyltaurate copolymer, an acrylic acid / alkyl methacrylate copolymer, and an acryloyl.
• a dimethyl taurine ammonium methacrylate Behnes-25 copolymer and a Na acrylate / Na acryloyl dimethyl taurate Na copolymer and an acrylic acid / alkyl methacrylate copolymer and an acryloyl dimethyl taurine ammonium methacrylate polymer. It is even more preferable to use the Hennes-25 copolymer.
• Aristoflex HMB manufactured by Clariant Japan Co., Ltd.
• PEMULEN TR-1 manufactured by Rubyzol Advanced Materials Co., Ltd.
• the content of the component (D) of the present invention is not particularly limited, but is preferably 0.01% or more in the oil-in-water emulsified cosmetic, and is 0 from the viewpoint of maintaining a moisturizing feeling. More preferably, it is 0.05% or more.
• the content of the component (D) is preferably 0.6% or less, more preferably 0.4% or less, and preferably 0.2% or less from the viewpoint of permeation and the like. Even more preferable.
• the content mass ratio [(B) + (C) + (D)] / (A) of the components (A) to (D) is not particularly limited, but is 0.1 or more. It is preferable that it is 0.2 or more, more preferably 0.3 or more, and still more preferably 0.4 or more, from the viewpoint of moisturizing feeling immediately after application and maintaining the moisturizing feeling. Especially preferable.
• the content mass ratio [(B) + (C) + (D)] / (A) is preferably 20 or less, and more preferably 10 or less, from the viewpoint of non-stickiness, permeation, and the like. Preferably, it is more preferably 5 or less, and particularly preferably 3 or less, from the viewpoint of the moisturizing feeling immediately after application and the maintenance of the moisturizing feeling.
• the oil-in-water emulsified cosmetic of the present invention can be an oil-in-water emulsified cosmetic that is excellent in permeation, moisturizing immediately after application, and sustaining moisturizing feeling.
• polyglycerin is a dimer or more glycerin, for example, diglycerin, triglycerin which is a trimeric of glycerin, tetraglycerin which is a tetramer of glycerin, and a hexamer of glycerin.
• one or more selected from diglycerin and triglycerin are preferable from the viewpoint of non-stickiness, and from the viewpoint of permeation, moisturizing immediately after application, and sustaining moisturizing feeling.
• Triglycerin is more preferred. Examples of these commercially available products include diglycerin 801 and PGL-S (all manufactured by Sakamoto Yakuhin Kogyo Co., Ltd.).
• the content of the component (E) of the present invention is not particularly limited, but is preferably 0.1% or more in the oil-in-water emulsified cosmetic, and has a permeation feeling, a moisturizing feeling immediately after application, and moisturizing. From the viewpoint of sustaining the feeling, it is more preferably 0.5% or more, and further preferably 1% or more. Further, the content of the component (E) is preferably 5% or less, more preferably 3% or less, and further more preferably 2% or less, from the viewpoint of non-stickiness and permeation feeling. preferable.
• the content mass ratios (C) / (E) of the components (C) and (E) are not particularly limited, but from the viewpoint of the moisturizing feeling immediately after application and the maintenance of the moisturizing feeling, etc. It is preferably 1 or more, more preferably 2 or more, and even more preferably 3 or more. Further, the content mass ratio (C) / (E) is preferably 15 or less, more preferably 10 or less, and further preferably 7 or less, from the viewpoint of non-stickiness, permeation, and the like. ..
• the present invention is an oil-in-water emulsified cosmetic and contains water.
• water is used as a dispersion medium for oils, and is not particularly limited as long as it is usually used for cosmetics.
• purified water distilled water, ion-exchanged water, tap water, hot spring water, deep ocean layer.
• Examples include water.
• the water content is not particularly limited, but is preferably 10 to 80%, more preferably 20 to 70% in the oil-in-water emulsified cosmetic.
• the oil-in-water emulsified cosmetic of the present invention can contain a surfactant as long as the effect of the present invention is not impaired.
• the surfactant can improve the stability of the oil-in-water emulsified cosmetic, and can be blended without particular limitation as long as it is usually used for cosmetics, quasi-drugs, pharmaceuticals, and the like. .. However, it is preferably 3% or less, and more preferably 1% or less, from the viewpoint of usability such as stickiness and permeation, and maintenance of moisturizing feeling while improving stability.
• the oil-in-water emulsified cosmetic of the present invention may contain, in addition to the above-mentioned essential ingredients, ingredients usually used in cosmetics, quasi-drugs, pharmaceuticals, etc., as long as the effects of the present invention are not impaired. That is, the oil-in-water emulsified cosmetic of the present invention includes, for example, a surfactant, a higher alcohol, a water-soluble polymer other than the component (D), a lower alcohol, a polyhydric alcohol, a film forming agent, a powder, a resin, and the like.
• Perfumes, deodorants, refreshing agents, ultraviolet absorbers, pH adjusters, preservatives, chelating agents, plant extracts, amino acids, vitamins, beauty ingredients, etc. may be appropriately contained within the range that does not impair the effects of the present invention. can.
• the oil-in-water emulsified cosmetic of the present invention can be used as a cosmetic for various purposes.
• cosmetics such as lotion, milky lotion, cream, beauty essence, massage cosmetics, pack cosmetics, hand cream, body lotion, body cream, makeup cosmetics, makeup base cosmetics, eye cream, sunscreen, etc.
• skin care cosmetics such as lotions, milky lotions, creams, beauty essences, massage cosmetics, facial masks, hand creams, body lotions, and body creams are preferable.
• Examples of the method of use include a method of using it with hands, fingers and cotton, a method of impregnating it with a non-woven fabric or the like, and the like.
• the properties of the oil-in-water emulsified lotion of the present invention can be implemented in various forms such as liquid, gel, emulsion, cream, semi-solid, and solid, and among them, liquid to gel. It is preferable to form the shape in order to obtain the effect of the present invention.
• the liquid to gel form has a viscosity of 30,000 mPa ⁇ s or less measured using a Brookfield type rotational viscometer at 25 ° C., preferably 20,000 mPa ⁇ s or less, and further. It is preferably 15,000 mPa ⁇ s or less.
• the method for producing the oil-in-water emulsified cosmetic of the present invention is not particularly limited and can be produced by a commonly known method. Specific examples thereof include a dispersion emulsification method, a phase inversion emulsification method, and a phase inversion temperature emulsification method. Be done.
• the manufacturing equipment may be any dispersion / emulsification equipment such as a general dispersion. For example, an oil phase in which the component (B) is heated and dissolved is added to an aqueous phase in which the components (C) to (E) and a part of purified water are mixed and dissolved, and the oil phase is emulsified and mixed by dispersion and then cooled.
• An oil-in-water emulsified cosmetic can be obtained by adding the component (A) dissolved in purified water.
• Evaluation method 1 Women in their 20s to 40s were trained in sensory evaluation, and 10 specialized panels that could be evaluated according to certain criteria were selected. In the specialized panel, 2 g of each sample was used for the forearm, and the non-stickiness at the time of use, the permeation feeling, and the moisturizing feeling immediately after application were evaluated and scored on a 4-point scale by the following absolute evaluation. The average value was calculated from the total score of all the panels for each sample, and the judgment was made according to the following four-step judgment criteria.
• the oil-in-water emulsified cosmetics of Examples 1 to 24 of the present invention have less stickiness and a feeling of penetration than the oil-in-water emulsified cosmetics of Comparative Examples 1 to 9. It was also excellent in moisturizing sensation immediately after application and in maintaining the moisturizing sensation.
• Comparative Examples 1 and 2 using liquid paraffin which does not contain the silicone oil of the component (B) or is a hydrocarbon oil are inferior in non-stickiness and maintenance of moisturizing feeling, and further permeate. No satisfactory feeling was obtained in terms of the feeling and the moisturizing feeling immediately after application. Then, a polyoxyalkylene-added glycerin derivative represented by a specific formula of the component (C), or a polyoxyalkylene-added glycerin derivative containing no polyoxypropylene skeleton, glycerin, or a polypropylene glycol containing no glycerin skeleton is used.
• Comparative Examples 3 to 6 used, satisfactory results were not obtained in all the results such as the continuation of the feeling of penetration and the feeling of moisturizing. Further, in Comparative Examples 7 to 9 in which the water-soluble polymer or the water-soluble polysaccharide which does not contain the amphipathic polymer of the component (D) or has no amphipathic property is used, in addition to the sustainability of the permeation feeling, Satisfactory results were not obtained in terms of non-stickiness, permeation feeling, and moisturizing feeling immediately after application.
• Example 25 Beauty essence (underwater oil type) (Component) (% by mass) (1) Niacinamide (component (A)) 3 (2) Tranexamic acid (ingredient (A)) 2 (3) (Acrylic acid / Alkyl acrylate (C10-30)) Copolymer (Component (D)) Note 6 0.3 (4) Acryloyldimethyltaurine ammonium / Behenes-25 methacrylic acid crosspolymer (component (D)) Note 7 0.05 (5) 1,3-butylene glycol 8 (6) Remaining amount of purified water (7) Glycerin 5 (8) EDTA-2Na 0.01 (9) Sodium hydrogen phosphate 0.3 (10) Sodium dihydrogen phosphate 0.6 (11) PEG / PPG / polyglycylene glycol / 8/5/3 glycerin (component (C)) Note 2 3 (12) Diglycerin 1 (13) Aureobasidium purulence culture 5 (14) Purified water 5 (15) Sodium
• Example 25 The beauty essence of Example 25 obtained as described above was excellent in non-stickiness, permeation feeling, moisturizing feeling immediately after application, and sustaining moisturizing feeling.
• the content mass ratio (A) / [(B) + (C)] of the components (A) to (C) was 0.9.
• Example 26 Emulsion (oil-in-water type) (Component) (% by mass) (1) Niacinamide (component (A)) 3 (2) Tranexamic acid (ingredient (A)) 2 (3) (Acrylic acid / alkyl acrylate (C10-30)) copolymer (component (D)) Note 6 0.15 (4) Carbomer 0.06 (5) 1,3-butylene glycol 8 (6) Remaining amount of purified water (7) Glycerin 5 (8) EDTA-2Na 0.01 (9) Polyoxypropylene (9) diglyceryl (component (C)) Note 4 2 (10) PEG / PPG / polyglycylene glycol / 8/5/3 glycerin (component (C)) Note 2 3 (11) Polyoxyethylene glycerin (26EO) Note 5 1 (12) Polyglyceryl-3 (Component (E)) Note 16 0.5 (13) Aureobasidium purulence culture 5 (14) Purified water 5 (15) Sodium
• A Ingredients (1) to (15) are uniformly mixed.
• B Ingredients (16) to (25) are heated to about 70 ° C., uniformly mixed and dissolved, added to A, emulsified, and then cooled.
• C B was filled in a container to obtain a milky lotion.
• the milky lotion (oil-in-water type) of Example 26 obtained as described above was excellent in non-stickiness, permeation feeling, moisturizing feeling immediately after application, and sustaining moisturizing feeling.
• the content mass ratio (A) / [(B) + (C)] of the components (A) to (C) was 0.5.
• Example 27 Sunscreen (underwater oil type) (Component) (% by mass) (1) 1,3-butylene glycol 5 (2) Dipropylene glycol 5 (3) Behentrimonium chloride 0.1 (4) Hydrogenated lecithin Note 12 0.5 (5) Cholesterol Note 13 0.6 (6) Phytosterol 0.1 (7) PEG / PPG / polyglycylene glycol / 8/5/3 glycerin (component (C)) Note 2 1 (8) Remaining amount of purified water (9) Niacinamide (component (A)) 3 (10) Tranexamic acid (component (A)) 2 (11) (Acrylic acid / Alkyl acrylate (C10-30)) Copolymer (Component (D)) Note 6 0.4 (12) Triethanolamine 0.4 (13) Dimethicodiethylbenzalmalonate 1.2 (14) 4-tert-Butyl-4'-methoxy-dibenzoylmethane 2 (15) 2-Ethylhexy
• the sunscreen agent (oil-in-water type) of Example 27 obtained as described above was excellent in non-stickiness, permeation feeling, moisturizing feeling immediately after application, and sustaining moisturizing feeling.
• the content mass ratio (A) / [(B) + (C)] of the components (A) to (C) was 2.5.
• Example 28 Toner (oil-in-water type) (Component) (% by mass) (1) PEG-20 hydrogenated castor oil 0.5 (2) Tori (palm oil fatty acid / palm kernel oil fatty acid / olive oil fatty acid / macadamia nut oil fatty acid / abrana seed oil fatty acid) glyceryl Note 15 0.07 (3) Phytosteryl oleate 0.01 (4) Dimethicone (6 mPa ⁇ s at 25 ° C) (Component (B)) 0.13 (5) Vitamin E 0.01 (6) Niacinamide (component (A)) 3 (7) Tranexamic acid (ingredient (A)) 2 (8) Acryloyldimethyltaurine ammonium / Behenes-25 methacrylic acid crosspolymer Note 7 (Component (D)) 0.05 (9) 1,3-butylene glycol 8 (10) Glycerin 5 (11) EDTA-2Na 0.01 (12) Sodium hydrogen phosphate 0.1 (13)
• Example 28 obtained as described above was excellent in non-stickiness, permeation feeling, moisturizing feeling immediately after application, and sustaining moisturizing feeling.

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• 2021
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