WO2021102113A1 - Sunscreen compositions with multiple photoprotecting uv filters - Google Patents

Sunscreen compositions with multiple photoprotecting uv filters Download PDF

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Publication number
WO2021102113A1
WO2021102113A1 PCT/US2020/061238 US2020061238W WO2021102113A1 WO 2021102113 A1 WO2021102113 A1 WO 2021102113A1 US 2020061238 W US2020061238 W US 2020061238W WO 2021102113 A1 WO2021102113 A1 WO 2021102113A1
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WO
WIPO (PCT)
Prior art keywords
filter
broad band
sunscreen composition
filters
certain embodiments
Prior art date
Application number
PCT/US2020/061238
Other languages
English (en)
French (fr)
Inventor
Marc Pissavini
Karine Julien
Carine GUILLERMINET
Olivier Doucet
Original Assignee
Coty Inc.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Coty Inc. filed Critical Coty Inc.
Priority to CN202080080833.7A priority Critical patent/CN114746070A/zh
Priority to EP20824816.1A priority patent/EP4061319A1/en
Priority to BR112022009548A priority patent/BR112022009548A2/pt
Publication of WO2021102113A1 publication Critical patent/WO2021102113A1/en

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Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
    • A61Q17/00—Barrier preparations; Preparations brought into direct contact with the skin for affording protection against external influences, e.g. sunlight, X-rays or other harmful rays, corrosive materials, bacteria or insect stings
    • A61Q17/04—Topical preparations for affording protection against sunlight or other radiation; Topical sun tanning preparations
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00—Cosmetics or similar toiletry preparations
    • A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/33—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing oxygen
    • A61K8/35—Ketones, e.g. benzophenone
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00—Cosmetics or similar toiletry preparations
    • A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/33—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing oxygen
    • A61K8/37—Esters of carboxylic acids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00—Cosmetics or similar toiletry preparations
    • A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/49—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing heterocyclic compounds
    • A61K8/4906—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing heterocyclic compounds with one nitrogen as the only hetero atom
    • A61K8/4926—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing heterocyclic compounds with one nitrogen as the only hetero atom having six membered rings

Definitions

  • compositions for use as sunscreens that comprise multiple photoprotecting UV filters.
  • the combination of UV filters provides efficient protection, upon application to exposed skin, from a broad range of UV wavelengths.
  • UV-A 320 to 400 nm
  • UV-B 290 to 320 nm
  • UV-C 200 to 290 nm
  • a sunscreen composition Provided is a sunscreen composition.
  • a UV filter composition comprising: three UV-B filters; a UV-A filter; and a UV-A + UV-B broadband filter.
  • sunscreen composition comprising a UV filter composition described herein.
  • Also provided is a method for protecting skin from sun damage comprising applying a sunscreen composition described herein to the skin.
  • FIG. 1 is a graph that shows that the in vivo SPF of Formula 1 and Formula 2 are substantially the same as the SPF of Comparative Formula, according to Example 5.
  • FIG. 2 is a graph that shows that Formula 1 has substantialy the same PPD as Comparative Formula, according to Example 5.
  • FIG. 3 is a graph that shows that Formula 1 has substantially the same SPF/PPD quotient as Comparative Formula, according to Example 5.
  • FIG. 4 is a graph that shows that Formula 3 has an improved SPF relative to
  • FIG. 5 is a graph that shows that Formula 3 has substantially the same SPF/PPD quotient as Comparative Formula, according to Example 5.
  • FIG. 6 is a graph that shows that Formula 3 has substantially the same SPF/PPD quotient as Comparative Formula, according to Example 5.
  • n1 and n2 are the numbers, then unless otherwise specified, this notation is intended to include the numbers themselves and the range between them. This range may be integral or continuous between and including the end values.
  • the range “from 2 to 6 carbons” is intended to include two, three, four, five, and six carbons, since carbons come in integer units. Compare, by way of example, the range “from 1 to 3 ⁇ (micromolar),” which is intended to include 1 ⁇ , 3 ⁇ , and everything in between to any number of significant figures (e.g., 1.255 ⁇ , 2.1 ⁇ , 2.9999 ⁇ , etc.).
  • the term “cosmetically effective amount” refers an amount of a physiologically active compound or composition sufficient for treating one or more conditions, but low enough to avoid serious side effects.
  • the cosmetically effective amount of the compound or composition will vary with the condition being treated, the age and physical condition of the end user, the severity of the condition being treated/prevented, the duration of the treatment, the nature of other treatments, the specific compound or product/composition employed, the cosmetically-acceptable carrier utilized, and like factors.
  • the term “cosmetically acceptable” means refers to a composition, the the ingredients of which being suitable for use in contact with tissues (e.g., the skin) without undue toxicity, irritation, incompatibility, instability, allergic response, or other adverse effect.
  • SPF protein protection factor
  • UV protection factor UV protection factor
  • the term “persistent pigment darkening”, abbreviated as “PPD”, is a method of measuring UVA protection, similar to the SPF method of measuring sunburn protection. Instead of measuring erythema, the PPD method uses UVA radiation to cause a persistent darkening or tanning of the skin. Theoretically, a sunscreen with a PPD rating of 10 should allow a person 10 times as much UVA exposure as would be without protection. Methods for determining PPD are known in the art.
  • UV-A refers to electromagnetic radiation having a wavelength between 320 and 400 nm.
  • UV-B refers to electromagnetic radiation having a wavelength between 290 and 320 nm.
  • broad spectrum UV refers to electromagnetic radiation having a wavelength from 290 to 400 nm. Determination of “ broad spectrum” is made in accordance with 21 C.F.R. 201.327(j) (2019).
  • critical wavelength is the wavelength at which the integral of the spectral absorbance curve is 90 percent of the integral over the UV spectrum from 290 to 400 nm.
  • the term “photostable” refers to the ability of a molecule to remain intact with irradiation. Photostability can be quantified by comparing the degree of protection and after irradiation. See, e.g., Pissavini, et al. (2012) “New Method to Reproduce In Vitro Cosmetic Product Photostability Findings” Cosmetics & Toiletries 127(3):208-218, which is incorporated by reference for all purposes. Other methods known in the art can also be used to determine photostability.
  • topical application refers to the directly application by spraying, wiping, or spreading on outer skin or the scalp. Topical application can be performed with the hands, or with the use of an applicator such as a wipe, roller, or spray.
  • cosmetic refers to a beautifying substance or preparation which preserves, restores, bestows, simulates, or enhances the appearance of bodily beauty or appears to enhance the beauty or youthfulness, specifically as it relates to the appearance of tissue or skin.
  • sunscreen composition refers to a formulation, including but not limited to: a spray, oil, lotion, cream, gel, butter, paste, ointment, stick, powder, wipe, towelette, body wash, shampoo, or other topical product, that absorbs and/or reflects some of the sun's ultraviolet (UV) radiation.
  • a sunscreen composition will thus provide protection against negative effects of sun exposure, e g. sunburn, premature aging, etc.
  • a UV filter composition comprising: three UV-B filters; a UV-A filter; and a UV-A + UV-B broadband filter.
  • a UV filter composition consisting of: three UV-B filters; a UV-A filter; and a UV-A + UV-B broadband filter.
  • the UV-A filter is chosen from • Butyl methoxydibenzoylmethane or l-(4-tert-Butylphenyl)-3-(4-methoxyphenyl) propane- 1 , 3 -dione,
  • the UV-A filter is chosen from butyl methoxydibenzoylmethane, diethylamino hydroxy benzoyl hexyl benzoate, disodium phenyl dibenzylimidazole tetrasulfonate, and terephthalylidene dicamphor sulfonic acid.
  • the UV-A filter is chosen from butyl methoxydibenzoylmethane, and menthyl anthranilate.
  • the UV-A filter is butyl methoxydibenzoylmethane.
  • the three UV-B filters are independently chosen from
  • PABA Aminobenzoic Acid
  • the three UV-B filters are independently chosen from ethylhexyl dimethyl PABA, ethylhexyl methoxycinnamate, ethylhexyl salicylate, homosalate, octocrylene, PABA, and phenyl benzimidazole sulfonic acid.
  • any compositions described herein can be free of octocrylene.
  • the three UV-B filters are independently chosen from 3- benzylidene camphor, benzylidene camphor sulfonic acid, camphor benzalkonium methosulfate, diethylhexyl butamido triazone, ethylhexyl dimethyl PABA.
  • ethylhexyl methoxycinnamate ethylhexyl methoxycinnamate
  • ethylhexyl salicylate ethylhexyl triazone
  • homosalate isoamyl p- methoxycinnamate
  • 4-methylbenzylidene camphor octocrylene
  • PABA PEG-25 PABA
  • phenyl benzimidazole sulfonic acid polyacrylamido methylbenzylidene camphor
  • polysilicone-15 polysilicone-15.
  • the three UV-B filters are independently chosen from cinoxate, ethylhexyl dimethyl PABA, ethylhexyl methoxycinnamate, ethylhexyl salicylate, homosalate, octocrylene, PABA, phenyl benzimidazole sulfonic acid, and TEA salicylate.
  • the three UV-B filters are independently chosen from isoamyl p-methoxycinnamate, ethylhexyl triazone, diethylhexyl butamido triazone, and ethylhexyl salicylate.
  • the three UV-B filters are isoamyl p- methoxycinnamate, ethylhexyl triazone, and octyl salicylate.
  • the broad band UV-A and UV-B filter is chosen from
  • the broad band UV-A and UV-B filter is chosen from benzophenone-3 and titanium dioxide.
  • the broad band UV-A and UV-B filter is chosen from benzophenone-3, benzophenone-4, benzophenone-5, bis- ethylhexyloxyphenol methoxyphenyl triazine, drometrizole trisiloxane, Methylene bis- benzotriazolyl tetramethylbutylphenol, and titanium dioxide.
  • the broad band UV-A and UV-B filter is chosen from benzophenone-3, benzophenone-4, benzophenone-8, titanium dioxide and zinc oxide.
  • the UV-A + UV- B broadband filter is bis ethylhexyloxyphenol methoxyphenyl triazine.
  • a UV filter composition comprising isoamyl p- methoxycinnamate, ethylhexyl triazone, octyl salicylate, butyl methoxydibenzoylmethane and bis-ethylhexyloxyphenol methoxyphenyl triazine.
  • UV filter composition consisting of isoamyl p- methoxycinnamate, ethylhexyl triazone, octyl salicylate, butyl methoxydibenzoylmethane and bis-ethylhexyloxyphenol methoxyphenyl triazine.
  • a UV filter composition comprising diethylhexyl butamido triazone, ethylhexyl triazone, octyl salicylate, butyl methoxydibenzoylmethane, and bis- ethylhexyloxyphenol methoxyphenyl triazine.
  • a UV filter composition consisting of diethylhexyl butamido triazone, ethylhexyl triazone, octyl salicylate, butyl methoxydibenzoylmethane, and bis- ethylhexyloxyphenol methoxyphenyl triazine.
  • UV filter composition comprising diethylhexyl butamido triazone, isoamyl p-methoxycinnamate, octyl salicylate, butyl methoxydibenzoylmethane, and bis-ethylhexyloxyphenol methoxyphenyl triazine.
  • UV filter composition consisting of diethylhexyl butamido triazone, isoamyl p-methoxycinnamate, octyl salicylate, butyl methoxydibenzoylmethane, and bis-ethylhexyloxyphenol methoxyphenyl triazine.
  • a sunscreen composition comprising a UV filter composition comprising isoamyl p-methoxycinnamate, ethylhexyl triazone, octyl salicylate, butyl methoxydibenzoylmethane and bis-ethylhexyloxyphenol methoxyphenyl triazine.
  • a sunscreen composition comprising a UV filter composition comprising diethylhexyl butamido triazone, ethylhexyl triazone, octyl salicylate, butyl methoxydibenzoylmethane, and bis-ethylhexyloxyphenol methoxyphenyl triazine.
  • a sunscreen composition comprising a UV filter composition comprising diethylhexyl butamido triazone, isoamyl p-methoxycinnamate, octyl salicylate, butyl methoxydibenzoylmethane, and bis-ethylhexyloxyphenol methoxyphenyl triazine.
  • the sunscreen composition does not comprise nanoparticles.
  • the sunscreen composition does not comprise benzonephenone-3.
  • the sunscreen composition does not comprise octyl methoxycinnamate.
  • the composition does not comprise a cinnamate ester other than isoamyl p-methoxy cinnamate.
  • the sunscreen composition does not comprise 2- ethylhexyl 2-cyano-3,3-diphenylacrylate. [061] In certain embodiments, the sunscreen composition does not comprise 2-
  • each of the UV filters in the sunscreen composition is present in an amount of from about 0.1 to about 25% w/w, about 0.1 to about 20% w/w, about 0.1 to about 18% w/w, 0.1 to about 15% w/w, about 0.1 to about 12% w/w, about 0.1 to about 10% w/w, 0.1 to about 8% w/w, about 0.1 to about 6% w/w, wherein the weight percent is based on the total weight of the sunscreen composition.
  • the sunscreen composition comprises less than about 35% w/w UV filters. In certain embodiments, the sunscreen composition comprises between about 5% and about 25% w/w UV filters. In certain embodiments, the sunscreen composition comprises about 20% w/w UV filters.
  • the sunscreen composition comprises the following: UV- A filter Butyl methoxydibenzoylmethane, UV-B filter Ethylhexyl triazone, UV-B filter octyl salicylate, UV-B filter Isoamyl p-methoxycinnamate, and broad band UV-A and UV-B filter bis-ethylhexyloxyphenol methoxyphenyl triazine.
  • the sunscreen composition comprises the following: UV- A filter Butyl methoxydibenzoylmethane, UV-B filter Ethylhexyl triazone, UV-B filter octyl salicylate, UV-B filter diethylhexyl butamido triazone, and broad band UV-A and UV-B filter bis-ethylhexyloxyphenol methoxyphenyl triazine.
  • the sunscreen composition comprises the following: UV- A filter Butyl methoxydibenzoylmethane, UV-B filter Isoamyl p-methoxycinnamate, UV-B filter octyl salicylate, UV-B filter diethylhexyl butamido triazone, and broad band UV-A and UV-B filter bis-ethylhexyloxyphenol methoxyphenyl triazine.
  • the sunscreen composition comprises the following: UV- A filter Butyl methoxydibenzoylmethane, UV-B filter Isoamyl p-methoxycinnamate, UV-B filter octyl salicylate, UV-B filter diethylhexyl butamido triazone, and broad band UV-A and UV-B filter bis-ethylhexyloxyphenol methoxyphenyl triazine.
  • the sunscreen composition comprises the following: UV-
  • the sunscreen composition comprises the following: UV- A filter Butyl methoxydibenzoylmethane, UV-B filter Ethylhexyl triazone, UV-B filter octyl salicylate, UV-B filter diethylhexyl butamido triazone, and broad band UV-A and UV-B filter bi s-ethylhexyloxyphenol methoxyphenyl triazine wherein the mass ratio of UV-A filter to UV-B filters to broad band filter is about 2 : 5.5 : 1.
  • the sunscreen composition comprises the following: UV- A filter Butyl methoxydibenzoylmethane, UV-B filter Isoamyl p-methoxycinnamate, UV-B filter octyl salicylate, UV-B filter diethylhexyl butamido triazone, and broad band UV-A and UV-B filter bis-ethylhexyloxyphenol methoxyphenyl triazine wherein the mass ratio of UV- A filter to UV-B filters to broad band filter is about 2 : 7 : 1.
  • the sunscreen composition comprises the following: UV- A filter Butyl methoxydibenzoylmethane, UV-B filter Ethylhexyl triazone, UV-B filter octyl salicylate, UV-B filter Isoamyl p-methoxycinnamate, and broad band UV-A and UV-B filter bis-ethylhexyloxyphenol methoxyphenyl triazine wherein the mass ratio of UV-A filter to UV-B filters to broad band filter is about 2 : 7 : 1.
  • the sunscreen composition comprises the following: UV- A filter Butyl methoxydibenzoylmethane, UV-B filter Ethylhexyl triazone, UV-B filter octyl salicylate, UV-B filter diethylhexyl butamido triazone, and broad band UV-A and UV-B filter bis-ethylhexyloxyphenol methoxyphenyl triazine wherein the mass ratio of UV-A filter to UV-B filters to broad band filter is about 4 : 11 : 2.
  • the sunscreen composition comprises the following: UV- A filter Butyl methoxydibenzoylmethane, UV-B filter Isoamyl p-methoxycinnamate, UV-B filter octyl salicylate, UV-B filter diethylhexyl butamido triazone, and broad band UV-A and UV-B filter bis-ethylhexyloxyphenol methoxyphenyl triazine wherein the mass ratio of UV- A filter to UV-B filters to broad band filter is about 1 : 3 : 1.
  • the sunscreen composition comprises the following: UV- A filter Butyl methoxydibenzoylmethane, UV-B filter Ethylhexyl triazone, UV-B filter octyl salicylate, UV-B filter Isoamyl p-methoxycinnamate, and broad band UV-A and UV-B filter bis-ethylhexyloxyphenol methoxyphenyl triazine wherein the mass ratio of UV-A filter to UV-B filters to broad band filter is about 4 : 13 : 2.
  • the sunscreen composition comprises the following: UV- A filter Butyl methoxydibenzoylmethane, UV-B filter Ethylhexyl triazone, UV-B filter octyl salicylate, UV-B filter diethylhexyl butamido triazone, and broad band UV-A and UV-B filter bis-ethylhexyloxyphenol methoxyphenyl triazine wherein the mass ratio of UV-A filter to UV-B filters to broad band filter is about 4 : 13 : 2.
  • the sunscreen composition comprises the following: UV- A filter Butyl methoxydibenzoylmethane, UV-B filter Isoamyl p-methoxycinnamate, UV-B filter octyl salicylate, UV-B filter diethylhexyl butamido triazone, and broad band UV-A and UV-B filter bis-ethylhexyloxyphenol methoxyphenyl triazine wherein the mass ratio of UV- A filter to UV-B filters to broad band filter is about 4 : 13 : 2.
  • the sunscreen composition comprises the following: UV- A filter Butyl methoxydibenzoylmethane, UV-B filter Ethylhexyl triazone, UV-B filter octyl salicylate, UV-B filter Isoamyl p-methoxycinnamate, and broad band UV-A and UV-B filter bis-ethylhexyloxyphenol methoxyphenyl triazine wherein the mass ratio of UV-A filter to UV-B filters to broad band filter is about 6 : 17 : 6.
  • the sunscreen composition comprises the following: UV- A filter Butyl methoxydibenzoylmethane, UV-B filter Ethylhexyl triazone, UV-B filter octyl salicylate, UV-B filter diethylhexyl butamido triazone, and broad band UV-A and UV-B filter bis-ethylhexyloxyphenol methoxyphenyl triazine wherein the mass ratio of UV-A filter to UV-B filters to broad band filter is about 6 : 17 : 4.
  • the sunscreen composition comprises the following: UV- A filter Butyl methoxydibenzoylmethane, UV-B filter Isoamyl p-methoxycinnamate, UV-B filter octyl salicylate, UV-B filter diethylhexyl butamido triazone, and broad band UV-A and UV-B filter bis-ethylhexyloxyphenol methoxyphenyl triazine wherein the mass ratio of UV- A filter to UV-B filters to broad band filter is about 6 : 17 : 6.
  • the sunscreen composition comprises the following: UV- A filter Butyl methoxydibenzoylmethane, UV-B filter Ethylhexyl triazone, UV-B filter octyl salicylate, UV-B filter Isoamyl p-methoxycinnamate, and broad band UV-A and UV-B filter bis-ethylhexyloxyphenol methoxyphenyl triazine wherein the mass ratio of UV-A filter to UV-B filters to broad band filter is about 7 : 13 : 6.
  • the sunscreen composition comprises the following: UV- A filter Butyl methoxydibenzoylmethane, UV-B filter Ethylhexyl triazone, UV-B filter octyl salicylate, UV-B filter diethylhexyl butamido triazone, and broad band UV-A and UV-B filter bis-ethylhexyloxyphenol methoxyphenyl triazine wherein the mass ratio of UV-A filter to UV-B filters to broad band filter is about 6 : 17 : 4.
  • the sunscreen composition comprises the following: UV- A filter Butyl methoxydibenzoylmethane, UV-B filter Isoamyl p-methoxycinnamate, UV-B filter octyl salicylate, UV-B filter diethylhexyl butamido triazone, and broad band UV-A and UV-B filter bis-ethylhexyloxyphenol methoxyphenyl triazine wherein the mass ratio of UV- A filter to UV-B filters to broad band filter is about 7 : 13 : 6.
  • the sunscreen composition comprises the following: UV- A filter Butyl methoxydibenzoylmethane, UV-B filter Ethylhexyl triazone, UV-B filter octyl salicylate, UV-B filter Isoamyl p-methoxycinnamate, and broad band UV-A and UV-B filter bis-ethylhexyloxyphenol methoxyphenyl triazine wherein the mass ratio of UV-A filter to UV-B filters to broad band filter is about 1 : 2 : 1.
  • the sunscreen composition comprises the following: UV- A filter Butyl methoxydibenzoylmethane, UV-B filter Ethylhexyl triazone, UV-B filter octyl salicylate, UV-B filter diethylhexyl butamido triazone, and broad band UV-A and UV-B filter bis-ethylhexyloxyphenol methoxyphenyl triazine wherein the mass ratio of UV-A filter to UV-B filters to broad band filter is about 3 : 8.5 : 2.
  • the sunscreen composition comprises the following: UV- A filter Butyl methoxydibenzoylmethane, UV-B filter Isoamyl p-methoxycinnamate, UV-B filter octyl salicylate, UV-B filter diethylhexyl butamido triazone, and broad band UV-A and UV-B filter bis-ethylhexyloxyphenol methoxyphenyl triazine wherein the mass ratio of UV- A filter to UV-B filters to broad band filter is about 1 : 2 : 1.
  • the sunscreen composition comprises the following: UV- A filter Butyl methoxydibenzoylmethane, UV-B filter Ethylhexyl triazone, UV-B filter octyl salicylate, UV-B filter Isoamyl p-methoxycinnamate, and broad band UV-A and UV-B filter bis-ethylhexyloxyphenol methoxyphenyl triazine wherein the mass ratio of UV-A filter to UV-B filters to broad band filter is about 7 : 11 : 6.
  • the sunscreen composition comprises the following: UV- A filter Butyl methoxydibenzoylmethane, UV-B filter Ethylhexyl triazone, UV-B filter octyl salicylate, UV-B filter diethylhexyl butamido triazone, and broad band UV-A and UV-B filter bis-ethylhexyloxyphenol methoxyphenyl triazine wherein the mass ratio of UV-A filter to UV-B filters to broad band filter is about 7 : 11 : 6.
  • the sunscreen composition comprises the following: UV- A filter Butyl methoxydibenzoylmethane, UV-B filter Isoamyl p-methoxy ci nnam ate, UV-B filter octyl salicylate, UV-B filter diethylhexyl butamido triazone, and broad band UV-A and UV-B filter bis-ethylhexyloxyphenol methoxyphenyl triazine wherein the mass ratio of UV- A filter to UV-B filters to broad band filter is about 7 : 11 : 6.
  • the sunscreen composition comprises the following: UV- A filter Butyl methoxydibenzoylmethane, UV-B filter Ethylhexyl triazone, UV-B filter octyl salicylate, UV-B filter Isoamyl p-methoxycinnamate, and broad band UV-A and UV-B filter bis-ethylhexyloxyphenol methoxyphenyl triazine wherein the mass ratio of UV-A filter to UV-B filters to broad band filter is about 9 : 24 : 8.
  • the sunscreen composition comprises the following: UV- A filter Butyl methoxydibenzoylmethane, UV-B filter Ethylhexyl triazone, UV-B filter octyl salicylate, UV-B filter diethylhexyl butamido triazone, and broad band UV-A and UV-B filter bis-ethylhexyloxyphenol methoxyphenyl triazine wherein the mass ratio of UV-A filter to UV-B filters to broad band filter is about 9 : 20 : 7.
  • the sunscreen composition comprises the following: UV- A filter Butyl methoxydibenzoylmethane, UV-B filter Isoamyl p-methoxycinnamate, UV-B filter octyl salicylate, UV-B filter diethylhexyl butamido triazone, and broad band UV-A and UV-B filter bis-ethylhexyloxyphenol methoxyphenyl triazine wherein the mass ratio of UV- A filter to UV-B filters to broad band filter is about 9 : 24 : 8.
  • the sunscreen composition comprises the following: UV- A filter Butyl methoxydibenzoylmethane, UV-B filter Ethylhexyl triazone, UV-B filter octyl salicylate, UV-B filter Isoamyl p-methoxycinnamate, and broad band UV-A and UV-B filter bis-ethylhexyloxyphenol methoxyphenyl triazine wherein the mass ratio of UV-A filter to UV-B filters to broad band filter is about 9 : 19 : 8.
  • the sunscreen composition comprises the following: UV- A filter Butyl methoxydibenzoylmethane, UV-B filter Ethylhexyl triazone, UV-B filter octyl salicylate, UV-B filter diethylhexyl butamido triazone, and broad band UV-A and UV-B filter bis-ethylhexyloxyphenol methoxyphenyl triazine wherein the mass ratio of UV-A filter to UV-B filters to broad band filter is about 9 : 19 : 8.
  • the sunscreen composition comprises the following: UV- A filter Butyl methoxydibenzoylmethane, UV-B filter Isoamyl p-methoxycinnamate, UV-B filter octyl salicylate, UV-B filter diethylhexyl butamido triazone, and broad band UV-A and UV-B filter bis-ethylhexyloxyphenol methoxyphenyl triazine wherein the mass ratio of UV- A filter to UV-B filters to broad band filter is about 9 : 19 : 8.
  • the sunscreen composition comprises the following: UV- A filter Butyl methoxydibenzoylmethane, UV-B filter Ethylhexyl triazone, UV-B filter octyl salicylate, UV-B filter Isoamyl p-methoxycinnamate, and broad band UV-A and UV-B filter bis-ethylhexyloxyphenol methoxyphenyl triazine wherein the mass ratio of UV-A filter to UV-B filters to broad band filter is about 9 : 17 : 8.
  • the sunscreen composition comprises the following: UV- A filter Butyl methoxydibenzoylmethane, UV-B filter Ethylhexyl triazone, UV-B filter octyl salicylate, UV-B filter diethylhexyl butamido triazone, and broad band UV-A and UV-B filter bis-ethylhexyloxyphenol methoxyphenyl triazine wherein the mass ratio of UV-A filter to UV-B filters to broad band filter is about 9 : 20 : 7.
  • the sunscreen composition comprises the following: UV- A filter Butyl methoxydibenzoylmethane, UV-B filter Isoamyl p-methoxycinnamate, UV-B filter octyl salicylate, UV-B filter diethylhexyl butamido triazone, and broad band UV-A and UV-B filter bis-ethylhexyloxyphenol methoxyphenyl triazine wherein the mass ratio of UV- A filter to UV-B filters to broad band filter is about 9 : 17 : 8.
  • the sunscreen composition comprises the following: UV- A filter Butyl methoxydibenzoylmethane, UV-B filter Ethylhexyl triazone, UV-B filter octyl salicylate, UV-B filter Isoamyl p-methoxycinnamate, and broad band UV-A and UV-B filter bis-ethylhexyloxyphenol methoxyphenyl triazine wherein the mass ratio of UV-A filter to UV-B filters to broad band filter is about 9 : 25 : 7.
  • the sunscreen composition comprises the following: UV- A filter Butyl methoxydibenzoylmethane, UV-B filter Ethylhexyl triazone, UV-B filter octyl salicylate, UV-B filter diethylhexyl butamido triazone, and broad band UV-A and UV-B filter bis-ethylhexyloxyphenol methoxyphenyl triazine wherein the mass ratio of UV-A filter to UV-B filters to broad band filter is about 9 : 25 : 7.
  • the sunscreen composition comprises the following: UV- A filter Butyl methoxydibenzoylmethane, UV-B filter Isoamyl p-methoxycinnamate, UV-B filter octyl salicylate, UV-B filter diethylhexyl butamido triazone, and broad band UV-A and UV-B filter bis-ethylhexyloxyphenol methoxyphenyl triazine wherein the mass ratio of UV- A filter to UV-B filters to broad band filter is about 9 : 25 : 7.
  • the sunscreen composition comprises the following: UV- A filter Butyl methoxydibenzoylmethane, UV-B filter Ethylhexyl triazone, UV-B filter octyl salicylate, UV-B filter Isoamyl p-methoxycinnamate, and broad band UV-A and UV-B filter bis-ethylhexyloxyphenol methoxyphenyl triazine wherein the mass ratio of UV-A filter to UV-B filters to broad band filter is about 9: 23 : 8.
  • the sunscreen composition comprises the following: UV- A filter Butyl methoxydibenzoylmethane, UV-B filter Ethylhexyl triazone, UV-B filter octyl salicylate, UV-B filter diethylhexyl butamido triazone, and broad band UV-A and UV-B filter bis-ethylhexyloxyphenol methoxyphenyl triazine wherein the mass ratio of UV-A filter to UV-B filters to broad band filter is about 9 : 23 : 8.
  • the sunscreen composition comprises the following: UV- A filter Butyl methoxydibenzoylmethane, UV-B filter Isoamyl p-methoxycinnamate, UV-B filter octyl salicylate, UV-B filter diethylhexyl butamido triazone, and broad band UV-A and UV-B filter bis-ethylhexyloxyphenol methoxyphenyl triazine wherein the mass ratio of UV- A filter to UV-B filters to broad band filter is about 9 : 23 : 8.
  • the sunscreen composition comprises the following: UV- A filter Butyl methoxydibenzoylmethane, UV-B filter Ethylhexyl triazone, UV-B filter octyl salicylate, UV-B filter Isoamyl p-methoxycinnamate, and broad band UV-A and UV-B filter bis-ethylhexyloxyphenol methoxyphenyl triazine wherein the mass ratio of UV-A filter to UV-B filters to broad band filter is about 9 : 18 : 8.
  • the sunscreen composition comprises the following: UV- A filter Butyl methoxydibenzoylmethane, UV-B filter Ethylhexyl triazone, UV-B filter octyl salicylate, UV-B filter diethylhexyl butamido triazone, and broad band UV-A and UV-B filter bis-ethylhexyloxyphenol methoxyphenyl triazine wherein the mass ratio of UV-A filter to UV-B filters to broad band filter is about 9 : 20 : 7.
  • the sunscreen composition comprises the following: UV- A filter Butyl methoxydibenzoylmethane, UV-B filter Isoamyl p-methoxycinnamate, UV-B filter octyl salicylate, UV-B filter diethylhexyl butamido triazone, and broad band UV-A and UV-B filter bis-ethylhexyloxyphenol methoxyphenyl triazine wherein the mass ratio of UV- A filter to UV-B filters to broad band filter is about 9 : 18 : 8.
  • the sunscreen composition comprises the following: UV- A filter Butyl methoxydibenzoylmethane, UV-B filter Ethylhexyl triazone, UV-B filter octyl salicylate, UV-B filter Isoamyl p-methoxycinnamate, and broad band UV-A and UV-B filter bis-ethylhexyloxyphenol methoxyphenyl triazine wherein the mass ratio of UV-A filter to UV-B filters to broad band filter is about 9 : 18 : 8.
  • the sunscreen composition comprises the following: UV- A filter Butyl methoxydibenzoylmethane, UV-B filter Ethylhexyl triazone, UV-B filter octyl salicylate, UV-B filter diethylhexyl butamido triazone, and broad band UV-A and UV-B filter bis-ethylhexyloxyphenol methoxyphenyl triazine wherein the mass ratio of UV-A filter to UV-B filters to broad band filter is about 9 : 20 : 7.
  • the sunscreen composition comprises the following: UV- A filter Butyl methoxydibenzoylmethane, UV-B filter Isoamyl p-methoxycinnamate, UV-B filter octyl salicylate, UV-B filter diethylhexyl butamido triazone, and broad band UV-A and UV-B filter bis-ethylhexyloxyphenol methoxyphenyl triazine wherein the mass ratio of UV- A filter to UV-B filters to broad band filter is about 9 : 18 : 8.
  • the sunscreen composition comprises the following: UV- A filter Butyl methoxydibenzoylmethane, UV-B filter Ethylhexyl triazone, UV-B filter octyl salicylate, UV-B filter Isoamyl p-methoxycinnamate, and broad band UV-A and UV-B filter bis-ethylhexyloxyphenol methoxyphenyl triazine wherein the mass ratio of UV-A filter to UV-B filters to broad band filter is about 9 : 15 : 8.
  • the sunscreen composition comprises the following: UV- A filter Butyl methoxydibenzoylmethane, UV-B filter Ethylhexyl triazone, UV-B filter octyl salicylate, UV-B filter diethylhexyl butamido triazone, and broad band UV-A and UV-B filter bis-ethylhexyloxyphenol methoxyphenyl triazine wherein the mass ratio of UV-A filter to UV-B filters to broad band filter is about 9 : 14 : 8.
  • the sunscreen composition comprises the following: UV- A filter Butyl methoxydibenzoylmethane, UV-B filter Isoamyl p-methoxy ci nnam ate, UV-B filter octyl salicylate, UV-B filter diethylhexyl butamido triazone, and broad band UV-A and UV-B filter bis-ethylhexyloxyphenol methoxyphenyl triazine wherein the mass ratio of UV- A filter to UV-B filters to broad band filter is about 9 : 15 : 8.
  • the sunscreen composition comprises the following: UV- A filter Butyl methoxydibenzoylmethane, UV-B filter Ethylhexyl triazone, UV-B filter octyl salicylate, UV-B filter Isoamyl p-methoxycinnamate, and broad band UV-A and UV-B filter bis-ethylhexyloxyphenol methoxyphenyl triazine wherein the mass ratio of UV-A filter to UV-B filters to broad band filter is about 9 : 16 : 8.
  • the sunscreen composition comprises the following: UV- A filter Butyl methoxydibenzoylmethane, UV-B filter Ethylhexyl triazone, UV-B filter octyl salicylate, UV-B filter diethylhexyl butamido triazone, and broad band UV-A and UV-B filter bis-ethylhexyloxyphenol methoxyphenyl triazine wherein the mass ratio of UV-A filter to UV-B filters to broad band filter is about 9 : 14 : 8.
  • the sunscreen composition comprises the following: UV- A filter Butyl methoxydibenzoylmethane, UV-B filter Isoamyl p-methoxycinnamate, UV-B filter octyl salicylate, UV-B filter diethylhexyl butamido triazone, and broad band UV-A and UV-B filter bis-ethylhexyloxyphenol methoxyphenyl triazine wherein the mass ratio of UV- A filter to UV-B filters to broad band filter is about 9 : 16 : 8.
  • the sunscreen composition comprises the following: UV- A filter Butyl methoxydibenzoylmethane, UV-B filter Ethylhexyl triazone, UV-B filter octyl salicylate, UV-B filter Isoamyl p-methoxycinnamate, and broad band UV-A and UV-B filter bis-ethylhexyloxyphenol methoxyphenyl triazine wherein the mass ratio of UV-A filter to UV-B filters to broad band filter is about 9 : 15 : 8.
  • the sunscreen composition comprises the following: UV- A filter Butyl methoxydibenzoylmethane, UV-B filter Ethylhexyl triazone, UV-B filter octyl salicylate, UV-B filter diethylhexyl butamido triazone, and broad band UV-A and UV-B filter bis-ethylhexyloxyphenol methoxyphenyl triazine wherein the mass ratio of UV-A filter to UV-B filters to broad band filter is about 9 : 14 : 8.
  • the sunscreen composition comprises the following: UV- A filter Butyl methoxydibenzoylmethane, UV-B filter Isoamyl p-methoxycinnamate, UV-B filter octyl salicylate, UV-B filter diethylhexyl butamido triazone, and broad band UV-A and UV-B filter bis-ethylhexyloxyphenol methoxyphenyl triazine wherein the mass ratio of UV- A filter to UV-B filters to broad band filter is about 9 : 15 : 8.
  • the ratio of UVAAJVB filters in the sunscreen composition is between about 0.6 and about 0.8. In certain embodiments, the ratio of UVAAJVB filters in the sunscreen composition is about 0.7.
  • the sunscreen composition has a mean critical wavelength of about 370 nm or greater. In certain embodiments, the sunscreen composition has a mean critical wavelength of about 375 nm.
  • the sunscreen composition has an SPF of at least about 15, such as about 15. In certain embodiments, the composition has an SPF of at least about
  • the composition has an SPF of at least about 50. In certain embodiments, the composition has an SPF of at least about 60.
  • the sunscreen composition further comprises a solubilizer.
  • the solubilizer acts to solubilize the UV filters.
  • the solubilizer acts to avoid solid particles formation.
  • the sunscreen composition comprises a lower level of solubilizers.
  • the ratio of UV solubilizers to UV filters is between about 0.5 and about 2.3, such as about 0.5, about 0.6, about 0.7, about 0.8, about 0.9, about 1, about 1.1, about 1.2, about 1.3, about 1.4, about 1.5, about 1.6, about 1.7, about 1.8, about 1.9, or about 2.0.
  • the sunscreen composition comprises at most about 36% w/w solubilizer. In certain embodiments, the sunscreen composition comprises about 20% w/w solubilizer. In certain embodiments, the sunscreen composition comprises less than about 20% w/w solubilizer. In certain embodiments, the sunscreen composition comprises between about 15 and 20% w/w solubilizer.
  • the sunscreen composition comprises between about 0.1% to about 5% w/w solubilizer. In certain embodiments, the sunscreen composition comprises between about 0.1% to about 15% w/w solubilizer. In certain embodiments, the sunscreen composition comprises between about 0.1% to about 25% w/W solubilizer. In certain embodiments, the sunscreen composition comprises between about 0.1% to about
  • the sunscreen composition comprises at least one solubilizer chosen from the one or more solubilizers are chosen from diisopropyl sebacate, dicapiylyl carbonate, decyl cocoate, diisopropyl adipate, isopropyl lauroyl sarcosinate, dibutyl adipate, butyloctyl salicylate, C 12-15 alkyl benzoate, and diethylhexyl succinate.
  • solubilizers are chosen from diisopropyl sebacate, dicapiylyl carbonate, decyl cocoate, diisopropyl adipate, isopropyl lauroyl sarcosinate, dibutyl adipate, butyloctyl salicylate, C 12-15 alkyl benzoate, and diethylhexyl succinate.
  • the sunscreen composition comprises at least one solubilizer chosen from Diisopropyl sebacate, Diisopropyl adipate, Dicapiylyl carbonate, Dibutyl adipate, Butyloctyl salicylate, Decyl cocoate, Cl 2- 15 alkyl benzoate, Diethylhexyl succinate, Diethylhexyl carbonate, and Isopropyl lauroyl sarcosinate.
  • solubilizer chosen from Diisopropyl sebacate, Diisopropyl adipate, Dicapiylyl carbonate, Dibutyl adipate, Butyloctyl salicylate, Decyl cocoate, Cl 2- 15 alkyl benzoate, Diethylhexyl succinate, Diethylhexyl carbonate, and Isopropyl lauroyl sarcosinate.
  • the sunscreen composition comprises two solubilizers chosen from Diisopropyl sebacate, Diisopropyl adipate, Dicapiylyl carbonate, Dibutyl adipate, Butyloctyl salicylate, Decyl cocoate, Cl 2- 15 alkyl benzoate, Diethylhexyl succinate, Diethylhexyl carbonate, and Isopropyl lauroyl sarcosinate.
  • solubilizers chosen from Diisopropyl sebacate, Diisopropyl adipate, Dicapiylyl carbonate, Dibutyl adipate, Butyloctyl salicylate, Decyl cocoate, Cl 2- 15 alkyl benzoate, Diethylhexyl succinate, Diethylhexyl carbonate, and Isopropyl lauroyl sarcosinate.
  • the sunscreen composition comprises three solubilizers chosen from Diisopropyl sebacate, Diisopropyl adipate, Dicaprylyl carbonate, Dibutyl adipate, Butyloctyl salicylate, Decyl cocoate, C12-15 alkyl benzoate, Diethylhexyl succinate, Diethylhexyl carbonate, and Isopropyl lauroyl sarcosinate.
  • solubilizers chosen from Diisopropyl sebacate, Diisopropyl adipate, Dicaprylyl carbonate, Dibutyl adipate, Butyloctyl salicylate, Decyl cocoate, C12-15 alkyl benzoate, Diethylhexyl succinate, Diethylhexyl carbonate, and Isopropyl lauroyl sarcosinate.
  • the sunscreen composition comprises 0.1% to 5% w/w of ethylhexyl salicylate and optionally at least one additional solubilizer.
  • the sunscreen composition comprises 0.1% to 25% w/w of at least one solubilizer chosen from Dibutyl adipate, Cl 2- 15 alkyl benzoate, Diethylhexyl succinate, Diethylhexyl carbonate, and Isopropyl lauroyl sarcosinate and optionally at least one additional solubilizer.
  • the sunscreen composition comprises 0.1 % to 25% w/w of at least one solubilizer chosen from Diisopropyl sebacate, Diisopropyl adipate, Dicaprylyl carbonate, and Decyl cocoate and optionally at least one additional solubilizer.
  • the sunscreen composition comprises: the UV-A filter is Butyl methoxydibenzoylmethane, a first UV-B filter is Ethylhexyl triazone, a second UV-B filter is octyl salicylate, a third UV-B filter is Isoamyl p-methoxycinnamate, and the broad band UV-A and UV-B filter is bis-ethylhexyloxyphenol methoxyphenyl triazine, wherein the mass ratio of UV-A filter to UV-B filters to broad band filter is about 2 :
  • composition comprises the solubilizer diisopropyl sebacate, such as from about 5% to about 9% of diisopropyl sebacate, e.g., from about 6% to about 8% of diisopropyl sebacate.
  • the sunscreen composition comprises: the UV-A filter is Butyl methoxydibenzoylmethane, a first UV-B filter is Ethylhexyl triazone, a second UV-B filter is octyl salicylate, a third UV-B filter is diethylhexyl butamido triazone, and the broad band UV-A and UV-B filter is bis-ethylhexyloxyphenol methoxyphenyl triazine, wherein the mass ratio of UV-A filter to UV-B filters to broad band filter is about 2 :
  • composition comprises the solubilizer diisopropyl sebacate, such as from about 8% to 10% of diisopropyl sebacate.
  • the sunscreen composition comprises: the UV-A filter is Butyl methoxydibenzoylmethane, a first UV-B filter is Isoamyl p-methoxycinnamate, a second UV-B filter is octyl salicylate, a third UV-B filter is diethylhexyl butamido triazone, and the broad band UV-A and UV-B filter is bis-ethylhexyloxyphenol methoxyphenyl triazine, wherein the mass ratio of UV-A filter to UV-B filters to broad band filter is about 2 :
  • composition comprises the solubilizer diisopropyl sebacate, such as from about 5% to about 9% of diisopropyl sebacate, e.g., from about 6% to about 8% of diisopropyl sebacate.
  • the sunscreen composition comprises: the UV-A filter is Butyl methoxydibenzoylmethane, a first UV-B filter is Ethylhexyl triazone, a second UV-B filter is octyl salicylate, a third UV-B filter is Isoamyl p-methoxycinnamate, and the broad band UV-A and UV-B filter is bis-ethylhexyloxyphenol methoxyphenyl triazine, wherein the mass ratio of UV-A filter to UV-B filters to broad band filter is about 2 :
  • composition comprises the solubilizer diisopropyl sebacate, such as from about 5% to about 9% of diisopropyl sebacate, e.g., from about 6% to about 8% of diisopropyl sebacate.
  • the sunscreen composition comprises: the UV-A filter is Butyl methoxydibenzoylmethane, a first UV-B filter is Ethylhexyl triazone, a second UV-B filter is octyl salicylate, a third UV-B filter is diethylhexyl butamido triazone, and the broad band UV-A and UV-B filter is bi s-ethylhexyloxyphenol methoxyphenyl triazine, wherein the mass ratio of UV-A filter to UV-B filters to broad band filter is about 4 :
  • composition comprises the solubilizer dibutyl adipate, such as from about 8% to about 11% of dibutyl adipate, e.g., from about 9% to about 10%.
  • the sunscreen composition comprises: the UV-A filter is Butyl methoxydibenzoylmethane, a first UV-B filter is Isoamyl p-methoxycinnamate, a second UV-B filter is octyl salicylate, a third UV-B filter is diethylhexyl butamido triazone, and the broad band UV-A and UV-B filter is bis-ethylhexyloxyphenol methoxyphenyl triazine, wherein the mass ratio of UV-A filter to UV-B filters to broad band filter is about 1 :
  • composition comprises the solubilizer diisopropyl sebacate, such as from about 5% to about 9% of diisopropyl sebacate, e.g., from about 6% to about 8% of diisopropyl sebacate.
  • the sunscreen composition comprises: the UV-A filter is Butyl methoxy dibenzoylmethane, a first UV-B filter is Ethylhexyl triazone, a second UV-B filter is octyl salicylate, a third UV-B filter is Isoamyl p-methoxycinnamate, and the broad band UV-A and UV-B filter is bis-ethylhexyloxyphenol methoxyphenyl triazine, wherein the mass ratio of UV-A filter to UV-B filters to broad band filter is about 4 :
  • composition comprises the solubilizer diisopropyl sebacate, such as from about 5% to about 9% of diisopropyl sebacate, e.g., from about 6% to about 8% of diisopropyl sebacate.
  • the sunscreen composition comprises: the UV-A filter is Butyl m ethoxy dibenzoylmethane, a first UV-B filter is Isoamyl p-methoxycinnamate, a second UV-B filter is octyl salicylate, a third UV-B filter is diethylhexyl butamido triazone, and the broad band UV-A and UV-B filter is bis-ethylhexyloxyphenol methoxyphenyl triazine, wherein the mass ratio of UV-A filter to UV-B filters to broad band filter is about 4 :
  • composition comprises the solubilizer diisopropyl sebacate, such as from about 5% to about 9% of diisopropyl sebacate, e.g., from about 6% to about 8% of diisopropyl sebacate.
  • the sunscreen composition comprises, wherein: the UV-A filter is Butyl methoxy dibenzoylmethane, a first UV-B filter is Ethylhexyl triazone, a second UV-B filter is octyl salicylate, a third UV-B filter is Isoamyl p-methoxycinnamate, and the broad band UV-A and UV-B filter is bis-ethylhexyloxyphenol methoxyphenyl triazine, wherein the mass ratio of UV-A filter to UV-B filters to broad band filter is about 6 : 17 : 4, and wherein the composition further comprises diisopropyl sebacate and dicapiylyl carbonate, such as from about 13% to about 15.5% of a mixture of diisopropyl sebacate and dicaprylyl carbonate, e.g., from about 13.5% to about 15% of a mixture of diisopropyl sebacate and dicapry
  • the sunscreen composition comprises: the UV-A filter is Butyl methoxydibenzoylmethane, a first UV-B filter is Ethylhexyl triazone, a second UV-B filter is octyl salicylate, a third UV-B filter is diethylhexyl butamido triazone, and the broad band UV-A and UV-B filter is bis-ethylhexyloxyphenol methoxyphenyl triazine, wherein the mass ratio of UV-A filter to UV-B filters to broad band filter is about 6 : 17 : 4 and wherein the composition further comprises diisopropyl sebacate and dicaprylyl carbonate, such as from about 13% to about 15.5% of a mixture of diisopropyl sebacate and dicaprylyl carbonate, e.g., from about 13.5% to about 15% of a mixture of diisopropyl sebacate and dicaprylyl carbonate
  • the sunscreen composition comprises: the UV-A filter is Butyl methoxydibenzoylmethane, a first UV-B filter is Isoamyl p-methoxycinnamate, a second UV-B filter is octyl salicylate, a third UV-B filter is diethylhexyl butamido triazone, and the broad band UV-A and UV-B filter is bis-ethylhexyloxyphenol methoxyphenyl triazine, wherein the mass ratio of UV-A filter to UV-B filters to broad band filter is about 6 : 17 : 4, and wherein the composition further comprises diisopropyl sebacate and dicaprylyl carbonate, such as from about 13% to about 15.5% of a mixture of diisopropyl sebacate and dicaprylyl carbonate, e g., from about 13.5% to about 15% of a mixture of diisopropyl sebacate and dicap
  • the sunscreen composition comprises: the UV-A filter is Butyl methoxydibenzoylmethane, a first UV-B filter is Ethylhexyl triazone, a second UV-B filter is octyl salicylate, a third UV-B filter is Isoamyl p-methoxycinnamate, and the broad band UV-A and UV-B filter is bis-ethylhexyloxyphenol methoxyphenyl triazine, wherein the mass ratio of UV-A filter to UV-B filters to broad band filter is about 7 : 17 : 6, and wherein the composition further comprises decyl cocoate, isopropyl lauroyl sarcosinate, and dibutyl adipate, such as from about 18% to about 20% of a mixture of decyl cocoate, isopropyl lauroyl sarcosinate, and dibutyl adipate, e.g.
  • the sunscreen composition comprises the UV-A filter is Butyl methoxydibenzoylmethane, a first UV-B filter is Ethylhexyl triazone, a second UV-B filter is octyl salicylate, a third UV-B filter is diethylhexyl butamido triazone, and the broad band UV-A and UV-B filter is bis-ethylhexyloxyphenol methoxyphenyl triazine, wherein the mass ratio of UV-A filter to UV-B filters to broad band filter is about is about 6 : 17: 4 and wherein the composition further comprises decyl cocoate, isopropyl lauroyl sarcosinate, and dibutyl adipate, such as from about 18% to about 20% of a mixture of decyl cocoate, isopropyl lauroyl sarcosinate, and dibutyl adipate, e g.,
  • the sunscreen composition comprises: the UV-A filter is Butyl methoxydibenzoylmethane, a first UV-B filter is Isoamyl p-methoxycinnamate, a second UV-B filter is octyl salicylate, a third UV-B filter is diethylhexyl butamido triazone, and the broad band UV-A and UV-B filter is bis-ethylhexyloxyphenol methoxyphenyl triazine, wherein the mass ratio of UV-A filter to UV-B filters to broad band filter is about 7 : 13 : 6, and wherein the composition further comprises decyl cocoate, isopropyl lauroyl sarcosinate, and dibutyl adipate, such as from about 16% to about 18% of a mixture of decyl cocoate, isopropyl lauroyl sarcosinate, and dibutyl adipate,
  • the sunscreen composition comprises: the UV-A filter is Butyl methoxydibenzoylmethane, a first UV-B filter is Ethylhexyl triazone, a second UV-B filter is octyl salicylate, a third UV-B filter is Isoamyl p-methoxycinnamate, and the broad band UV-A and UV-B filter is bis-ethylhexyloxyphenol methoxyphenyl triazine, wherein the mass ratio of UV-A filter to UV-B filters to broad band filter is about 1 :
  • composition further comprises decyl cocoate and diisopropyl sebacate, such as from about 19% to about 21% of a mixture of decyl cocoate and diisopropyl sebacate, e.g., from about 19.5% to about 20.5% of a mixture of decyl cocoate and diisopropyl se.
  • the sunscreen composition comprises, wherein: the UV-A filter is Butyl methoxydibenzoylmethane, a first UV-B filter is Ethylhexyl triazone, a second UV-B filter is octyl salicylate, a third UV-B filter is diethylhexyl butamido triazone, and the broad band UV-A and UV-B filter is bis-ethylhexyloxyphenol methoxyphenyl triazine, wherein the mass ratio of UV-A filter to UV-B filters to broad band filter is about 3 : 8.5 : 2, and wherein the composition further comprises decyl cocoate and diisopropyl sebacate, such as from about 19% to about 21% of a mixture of decyl cocoate and diisopropyl sebacate, e.g., from about 19.5% to about 20.5% of a mixture of decyl cocoate and diisopropyl
  • the sunscreen composition comprises: the UV-A filter is Butyl methoxydibenzoylmethane, a first UV-B filter is Isoamyl p-methoxy ci nnam ate, a second UV-B filter is octyl salicylate, a third UV-B filter is diethylhexyl butamido triazone, and the broad band UV-A and UV-B filter is bis-ethylhexyloxyphenol methoxyphenyl triazine, wherein the mass ratio of UV-A filter to UV-B filters to broad band filter is about 1 :
  • composition further comprises decyl cocoate and diisopropyl sebacate, such as from about 19% to about 21% of a mixture of decyl cocoate and diisopropyl sebacate, e.g., from about 19.5% to about 20.5% of a mixture of decyl cocoate and diisopropyl se.
  • the sunscreen composition comprises, wherein: the UV-A filter is Butyl methoxydibenzoylmethane, a first UV-B filter is Ethylhexyl triazone, a second UV-B filter is octyl salicylate, a third UV-B filter is Isoamyl p-methoxycinnamate, and the broad band UV-A and UV-B filter is bis-ethylhexyloxyphenol methoxyphenyl triazine, w wherein the mass ratio of UV-A filter to UV-B filters to broad band filter is about 7
  • composition further comprises diisopropyl sebacate, dicaprylyl carbonate, and decyl cocoate, such as from about 19.5% to about 21.5% of a mixture of diisopropyl sebacate, dicaprylyl carbonate, and decyl cocoate, e.g., from about 20% to about 21% of a mixture of diisopropyl sebacate, dicaprylyl carbonate, and decyl cocoate.
  • diisopropyl sebacate, dicaprylyl carbonate, and decyl cocoate such as from about 19.5% to about 21.5% of a mixture of diisopropyl sebacate, dicaprylyl carbonate, and decyl cocoate, e.g., from about 20% to about 21% of a mixture of diisopropyl sebacate, dicaprylyl carbonate, and decyl cocoate.
  • the sunscreen composition comprises, wherein: the UV-A filter is Butyl methoxydibenzoylmethane, a first UV-B filter is Ethylhexyl triazone, a second UV-B filter is octyl salicylate, a third UV-B filter is diethylhexyl butamido triazone, and the broad band UV-A and UV-B filter is bis-ethylhexyloxyphenol methoxyphenyl triazine, wherein the mass ratio of UV-A filter to UV-B filters to broad band filter is about 6 :
  • composition further comprises diisopropyl sebacate, dicaprylyl carbonate, and decyl cocoate, such as from about 19.5% to about 21.5% of a mixture of diisopropyl sebacate, dicaprylyl carbonate, and decyl cocoate, e.g., from about 20% to about 21% of a mixture of diisopropyl sebacate, dicaprylyl carbonate, and decyl cocoate.
  • diisopropyl sebacate, dicaprylyl carbonate, and decyl cocoate such as from about 19.5% to about 21.5% of a mixture of diisopropyl sebacate, dicaprylyl carbonate, and decyl cocoate, e.g., from about 20% to about 21% of a mixture of diisopropyl sebacate, dicaprylyl carbonate, and decyl cocoate.
  • the sunscreen composition comprises: the UV-A filter is Butyl methoxydibenzoylmethane, a first UV-B filter is Isoamyl p-methoxyci nnam ate, a second UV-B filter is octyl salicylate, a third UV-B filter is diethylhexyl butamido triazone, and the broad band UV-A and UV-B filter is bi s-ethylhexyloxyphenol methoxyphenyl triazine, wherein the mass ratio of UV-A filter to UV-B filters to broad band filter is about 7 :
  • composition further comprises diisopropyl sebacate, dicaprylyl carbonate, and decyl cocoate, such as from about 19.5% to about 21.5% of a mixture of diisopropyl sebacate, dicaprylyl carbonate, and decyl cocoate, e.g., from about 20% to about 21% of a mixture of diisopropyl sebacate, dicaprylyl carbonate, and decyl cocoate.
  • diisopropyl sebacate, dicaprylyl carbonate, and decyl cocoate such as from about 19.5% to about 21.5% of a mixture of diisopropyl sebacate, dicaprylyl carbonate, and decyl cocoate, e.g., from about 20% to about 21% of a mixture of diisopropyl sebacate, dicaprylyl carbonate, and decyl cocoate.
  • the sunscreen composition comprises: the UV-A filter is Butyl methoxydibenzoylmethane, a first UV-B filter is Ethylhexyl triazone, a second UV-B filter is octyl salicylate, a third UV-B filter is Isoamyl p-methoxycinnamate, and the broad band UV-A and UV-B filter is bi s-ethylhexyloxyphenol methoxyphenyl triazine, wherein the mass ratio of UV-A filter to UV-B filters to broad band filter is about 6 :
  • composition further comprises diisopropyl sebacate, decyl cocoate, and isopropyl lauroyl sarcosinate, such as from about 16% to about 18% of a mixture of diisopropyl sebacate, decyl cocoate, and isopropyl lauroyl sarcosinate, e.g., from about 16.5% to about 17.5% of a mixture of diisopropyl sebacate, decyl cocoate, and isopropyl lauroyl sarcosinate.
  • the sunscreen composition comprises: the UV-A filter is Butyl methoxydibenzoylmethane, a first UV-B filter is Ethylhexyl triazone, a second UV-B filter is octyl salicylate, a third UV-B filter is diethylhexyl butamido triazone, and the broad band UV-A and UV-B filter is bis-ethylhexyloxyphenol methoxyphenyl triazine, wherein the mass ratio of UV-A filter to UV-B filters to broad band filter is about 6 :
  • composition further comprises diisopropyl sebacate, decyl cocoate, and isopropyl lauroyl sarcosinate, such as from about 16% to about 18% of a mixture of diisopropyl sebacate, decyl cocoate, and isopropyl lauroyl sarcosinate, e.g., from about 16.5% to about 17.5% of a mixture of diisopropyl sebacate, decyl cocoate, and isopropyl lauroyl sarcosinate.
  • the sunscreen composition comprises: the UV-A filter is Butyl methoxydibenzoylmethane, a first UV-B filter is Isoamyl p-methoxycinnamate, a second UV-B filter is octyl salicylate, a third UV-B filter is diethylhexyl butamido tiiazone, and the broad band UV-A and UV-B filter is bis-ethylhexyloxyphenol methoxyphenyl triazine, wherein the mass ratio of UV-A filter to UV-B filters to broad band filter is about 7 : 11: 6, and wherein the composition further comprises diisopropyl sebacate, decyl cocoate, and isopropyl lauroyl sarcosinate, such as from about 16% to about 18% of a mixture of diisopropyl sebacate, decyl cocoate, and isopropyl lauroyl sarc
  • the sunscreen composition comprises: the UV-A filter is Butyl methoxydibenzoylmethane, a first UV-B filter is Ethylhexyl triazone, a second UV-B filter is octyl salicylate, a third UV-B filter is Isoamyl p-methoxycinnamate, and the broad band UV-A and UV-B filter is bis-ethylhexyloxyphenol methoxyphenyl triazine, wherein the mass ratio of UV-A filter to UV-B filters to broad band filter is about 9 : 24 : 8, and wherein the composition further comprises diisopropyl sebacate, dicaprylyl carbonate, and decyl cocoate, such as from about 18% to about 22% of a mixture of diisopropyl sebacate, dicaprylyl carbonate, and decyl cocoate, e.g., from about 19% to about 21% of a mixture
  • the sunscreen composition comprises: the UV-A filter is Butyl methoxydibenzoylmethane, a first UV-B filter is Ethylhexyl triazone, a second UV-B filter is octyl salicylate, a third UV-B filter is diethylhexyl butamido triazone, and the broad band UV-A and UV-B filter is bis-ethylhexyloxyphenol methoxyphenyl triazine, wherein the mass ratio of UV-A filter to UV-B filters to broad band filter is about 9 : 20 : 7 and wherein the composition further comprises diisopropyl sebacate, dicaprylyl carbonate, and decyl cocoate, such as from about 25% to about 29% of a mixture of diisopropyl sebacate, dicaprylyl carbonate, and decyl cocoate, e.g., from about 26% to about 28% of a mixture of di
  • the sunscreen composition comprises: the UV-A filter is Butyl methoxydibenzoylmethane, a first UV-B filter is Isoamyl p-methoxycinnamate, a second UV-B filter is octyl salicylate, a third UV-B filter is diethylhexyl butamido triazone, and the broad band UV-A and UV-B filter is bis-ethylhexyloxyphenol methoxyphenyl triazine, wherein the mass ratio of UV-A filter to UV-B filters to broad band filter is about 9 : 24 : 8, and wherein the composition further comprises diisopropyl sebacate, dicaprylyl carbonate, and decyl cocoate, such as from about 25% to about 29% of a mixture of diisopropyl sebacate, dicaprylyl carbonate, and decyl cocoate, e.g., from about 26% to about 28% of
  • the sunscreen composition comprises: the UV-A filter is Butyl methoxydibenzoylmethane, a first UV-B filter is Ethylhexyl triazone, a second UV-B filter is octyl salicylate, a third UV-B filter is Isoamyl p-methoxycinnamate, and the broad band UV-A and UV-B filter is bis-ethylhexyloxyphenol methoxyphenyl triazine, wherein the mass ratio of UV-A filter to UV-B filters to broad band filter is about 9 : 24 : 8, and wherein the composition further comprises diisopropyl sebacate and diisopropyl adipate, such as from about 32.5% to about 35.5% of a mixture of diisopropyl sebacate and diisopropyl adipate, e.g., from about 33% to about 35% of a mixture of diisopropyl se
  • the sunscreen composition comprises: the UV-A filter is Butyl methoxydibenzoylmethane, a first UV-B filter is Ethylhexyl triazone, a second UV-B filter is octyl salicylate, a third UV-B filter is diethylhexyl butamido triazone, and the broad band UV-A and UV-B filter is bis-ethylhexyloxyphenol methoxyphenyl triazine, wherein the mass ratio of UV-A filter to UV-B filters to broad band filter is 9 : 20 : 7, and wherein the composition further comprises diisopropyl sebacate and diisopropyl adipate, such as from about 32.5% to about 35.5% of a mixture of diisopropyl sebacate and diisopropyl adipate, e.g., from about 33% to about 35% of a mixture of diisopropyl sebacate
  • the sunscreen composition comprises: the UV-A filter is Butyl methoxydibenzoylmethane, a first UV-B filter is Isoamyl p-methoxy ci nnam ate, a second UV-B filter is octyl salicylate, a third UV-B filter is diethylhexyl butamido triazone, and the broad band UV-A and UV-B filter is bis-ethylhexyloxyphenol methoxyphenyl triazine, wherein the mass ratio of UV-A filter to UV-B filters to broad band filter is about 9 :
  • composition further comprises diisopropyl sebacate and diisopropyl adipate, such as from about 32.5% to about 35.5% of a mixture of diisopropyl sebacate and diisopropyl adipate, e.g., from about 33% to about 35% of a mixture of diisopropyl sebacate and diisopropyl adipate.
  • diisopropyl sebacate and diisopropyl adipate such as from about 32.5% to about 35.5% of a mixture of diisopropyl sebacate and diisopropyl adipate, e.g., from about 33% to about 35% of a mixture of diisopropyl sebacate and diisopropyl adipate.
  • the sunscreen composition comprises: the UV-A filter is Butyl methoxydibenzoylmethane, a first UV-B filter is Ethylhexyl triazone, a second UV-B filter is octyl salicylate, a third UV-B filter is Isoamyl p-methoxycinnamate, and the broad band UV-A and UV-B filter is bis-ethylhexyloxyphenol methoxyphenyl triazine, wherein the mass ratio of UV-A filter to UV-B filters to broad band filter is about 9 : 24 : 8, and wherein the composition further comprises diisopropyl sebacate, decyl cocoate and isopropyl lauroyl sarcosinate, such as from about 22.5% to about 25.5% of a mixture of diisopropyl sebacate, decyl cocoate and isopropyl lauroyl sarcosinate, e
  • the sunscreen composition comprises: the UV-A filter is Butyl methoxydibenzoylmethane, a first UV-B filter is Ethylhexyl triazone, a second UV-B filter is octyl salicylate, a third UV-B filter is diethylhexyl butamido triazone, and the broad band UV-A and UV-B filter is bis-ethylhexyloxyphenol methoxyphenyl triazine, wherein the mass ratio of UV-A filter to UV-B filters to broad band filter is about 9 : 20 : 7, wherein the composition further comprises diisopropyl sebacate, decyl cocoate and isopropyl lauroyl sarcosinate, such as from about 22.5% to about 25.5% of a mixture of diisopropyl sebacate, decyl cocoate and isopropyl lauroyl sarcosinate, e.g
  • the sunscreen composition comprises: the UV-A filter is Butyl methoxydibenzoylmethane, a first UV-B filter is Isoamyl p-methoxycinnamate, a second UV-B filter is octyl salicylate, a third UV-B filter is diethylhexyl butamido triazone, and the broad band UV-A and UV-B filter is bis-ethylhexyloxyphenol methoxyphenyl triazine, wherein the mass ratio of UV-A filter to UV-B filters to broad band filter is about 9 : 24 : 8, and wherein the composition further comprises diisopropyl sebacate, decyl cocoate and isopropyl lauroyl sarcosinate, such as from about 22.5% to about 25.5% of a mixture of diisopropyl sebacate, decyl cocoate and isopropyl lauroyl sarcos
  • the sunscreen composition comprises: the UV-A filter is Butyl methoxydibenzoylmethane, a first UV-B filter is Ethylhexyl triazone, a second UV-B filter is octyl salicylate, a third UV-B filter is Isoamyl p-methoxycinnamate, and the broad band UV-A and UV-B filter is bis-ethylhexyloxyphenol methoxyphenyl triazine, wherein the mass ratio of UV-A filter to UV-B filters to broad band filter is about 9 : 24 : 8, and wherein the composition further comprises decyl cocoate, isopropyl lauroyl sarcosinate, and dibutyl adipate, such as from about 28% to about 31% of a mixture of decyl cocoate, isopropyl lauroyl sarcosinate, and dibutyl adipate, e.g
  • the sunscreen composition comprises: the UV-A filter is Butyl methoxydibenzoylmethane, a first UV-B filter is Ethylhexyl triazone, a second UV-B filter is octyl salicylate, a third UV-B filter is diethylhexyl butamido triazone, and the broad band UV-A and UV-B filter is bis-ethylhexyloxyphenol methoxyphenyl triazine, wherein the mass ratio of UV-A filter to UV-B filters to broad band filter is about 9 : 20 : 7, and wherein the composition further comprises decyl cocoate, isopropyl lauroyl sarcosinate, and dibutyl adipate, such as from about 28% to about 31% of a mixture of decyl cocoate, isopropyl lauroyl sarcosinate, and dibutyl adipate, e.g.
  • the sunscreen composition comprises: the UV-A filter is Butyl methoxydibenzoylmethane, a first UV-B filter is Isoamyl p-methoxy ci nnam ate, a second UV-B filter is octyl salicylate, a third UV-B filter is diethylhexyl butamido triazone, and the broad band UV-A and UV-B filter is bis-ethylhexyloxyphenol methoxyphenyl triazine, wherein the mass ratio of UV-A filter to UV-B filters to broad band filter is about 9 : 24 : 8, and wherein the composition further comprises decyl cocoate, isopropyl lauroyl sarcosinate, and dibutyl adipate, such as from about 28% to about 31% of a mixture of decyl cocoate, isopropyl lauroyl sarcosinate, and dibutyl
  • the sunscreen composition comprises: the UV-A filter is Butyl methoxydibenzoylmethane, a first UV-B filter is Ethylhexyl triazone, a second UV-B filter is octyl salicylate, a third UV-B filter is Isoamyl p-methoxycinnamate, and the broad band UV-A and UV-B filter is bis-ethylhexyloxyphenol methoxyphenyl triazine, wherein the mass ratio of UV-A filter to UV-B filters to broad band filter is about 9 :
  • composition further comprises diisopropyl sebacate, decyl cocoate, and isopropyl lauroyl sarcosinate, such as from about 18% to about 22% of a mixture of diisopropyl sebacate, decyl cocoate, and isopropyl lauroyl sarcosinate, e.g., from about 20% to about 21% of a mixture of diisopropyl sebacate, decyl cocoate, and isopropyl lauroyl sarcosinate.
  • diisopropyl sebacate, decyl cocoate, and isopropyl lauroyl sarcosinate such as from about 18% to about 22% of a mixture of diisopropyl sebacate, decyl cocoate, and isopropyl lauroyl sarcosinate, e.g., from about 20% to about 21% of a mixture of diisopropyl sebacate, decyl
  • the sunscreen composition comprises: the UV-A filter is Butyl methoxydibenzoylmethane, a first UV-B filter is Isoamyl p-methoxy ci nnam ate, a second UV-B filter is octyl salicylate, a third UV-B filter is diethylhexyl butamido triazone, and the broad band UV-A and UV-B filter is bis-ethylhexyloxyphenol methoxyphenyl triazine, wherein the mass ratio of UV-A filter to UV-B filters to broad band filter is about 9 :
  • composition further comprises diisopropyl sebacate, decyl cocoate, and isopropyl lauroyl sarcosinate, such as from about 18% to about 22% of a mixture of diisopropyl sebacate, decyl cocoate, and isopropyl lauroyl sarcosinate, e.g., from about 20% to about 21% of a mixture of diisopropyl sebacate, decyl cocoate, and isopropyl lauroyl sarcosinate.
  • diisopropyl sebacate, decyl cocoate, and isopropyl lauroyl sarcosinate such as from about 18% to about 22% of a mixture of diisopropyl sebacate, decyl cocoate, and isopropyl lauroyl sarcosinate, e.g., from about 20% to about 21% of a mixture of diisopropyl sebacate, decyl
  • the sunscreen composition comprises: the UV-A filter is Butyl methoxydibenzoylmethane, a first UV-B filter is Ethylhexyl triazone, a second UV-B filter is octyl salicylate, a third UV-B filter is Isoamyl p-methoxycinnamate, and the broad band UV-A and UV-B filter is bis-ethylhexyloxyphenol methoxyphenyl triazine, wherein the mass ratio of UV-A filter to UV-B filters to broad band filter is about 9 :
  • composition further comprises diisopropyl sebacate, diisopropyl adipate, and decyl cocoate, such as from about 29% to about 33% of a mixture of diisopropyl sebacate, diisopropyl adipate, and decyl cocoate, e g., from about 30% to about 32% of a mixture of diisopropyl sebacate, diisopropyl adipate, and decyl cocoate.
  • diisopropyl sebacate diisopropyl adipate
  • decyl cocoate such as from about 29% to about 33% of a mixture of diisopropyl sebacate, diisopropyl adipate, and decyl cocoate, e g., from about 30% to about 32% of a mixture of diisopropyl sebacate, diisopropyl adipate, and decyl cocoate.
  • the sunscreen composition comprises: the UV-A filter is Butyl methoxydibenzoylmethane, a first UV-B filter is Isoamyl p-methoxycinnamate, a second UV-B filter is octyl salicylate, a third UV-B filter is diethylhexyl butamido triazone, and the broad band UV-A and UV-B filter is bis-ethylhexyloxyphenol methoxyphenyl triazine, wherein the mass ratio of UV-A filter to UV-B filters to broad band filter is about 9 :
  • composition further comprises diisopropyl sebacate, diisopropyl adipate, and decyl cocoate, such as from about 29% to about 33% of a mixture of diisopropyl sebacate, diisopropyl adipate, and decyl cocoate, e.g.,from about 30% to about 32% of a mixture of diisopropyl sebacate, diisopropyl adipate, and decyl cocoate.
  • diisopropyl sebacate diisopropyl adipate
  • decyl cocoate such as from about 29% to about 33% of a mixture of diisopropyl sebacate, diisopropyl adipate, and decyl cocoate, e.g.,from about 30% to about 32% of a mixture of diisopropyl sebacate, diisopropyl adipate, and decyl cocoate.
  • the sunscreen composition comprises: the UV-A filter is Butyl methoxydibenzoylmethane, a first UV-B filter is Ethylhexyl triazone, a second UV-B filter is octyl salicylate, a third UV-B filter is Isoamyl p-methoxycinnamate, and the broad band UV-A and UV-B filter is bis-ethylhexyloxyphenol methoxyphenyl triazine, wherein the mass ratio of UV-A filter to UV-B filters to broad band filter is about 9 : 17 : 8, and wherein the composition further comprises diisopropyl sebacate, diisopropyl adipate, and decyl cocoate, such as from about 25% to about 28% of a mixture of diisopropyl sebacate, diisopropyl adipate, and decyl cocoate, e.g., from about 26% to about 2
  • the sunscreen composition comprises: the UV-A filter is Butyl methoxydibenzoylmethane, a first UV-B filter is Ethylhexyl triazone, a second UV-B filter is octyl salicylate, a third UV-B filter is diethylhexyl butamido triazone, and the broad band UV-A and UV-B filter is bis-ethylhexyloxyphenol methoxyphenyl triazine, wherein the mass ratio of UV-A filter to UV-B filters to broad band filter is about 9 : 20 : 7, and wherein the composition further comprises diisopropyl sebacate, diisopropyl adipate, and decyl cocoate, such as from about 25% to about 28% of a mixture of diisopropyl sebacate, diisopropyl adipate, and decyl cocoate, e.g., from about 26% to about 27%
  • the sunscreen composition comprises: the UV-A filter is Butyl methoxydibenzoylmethane, a first UV-B filter is Isoamyl p-methoxycinnamate, a second UV-B filter is octyl salicylate, a third UV-B filter is diethylhexyl butamido triazone, and the broad band UV-A and UV-B filter is bis-ethylhexyloxyphenol methoxyphenyl triazine, wherein the mass ratio of UV-A filter to UV-B filters to broad band filter is about 9 : 17 : 8, and wherein the composition further comprises diisopropyl sebacate, diisopropyl adipate, and decyl cocoate, such as from about 25% to about 28% of a mixture of diisopropyl sebacate, diisopropyl adipate, and decyl cocoate, e.g., from about 2
  • the sunscreen composition comprises: the UV-A filter is Butyl methoxydibenzoylmethane, a first UV-B filter is Ethylhexyl triazone, a second UV-B filter is octyl salicylate, a third UV-B filter is Isoamyl p-methoxycinnamate, and the broad band UV-A and UV-B filter is bis-ethylhexyloxyphenol methoxyphenyl triazine, wherein the mass ratio of UV-A filter to UV-B filters to broad band filter is about 9 : 25 : 7 and wherein the composition further comprises diisopropyl sebacate and dicaprylyl carbonate, such as from about 17% to about 20% of a mixture of diisopropyl sebacate and dicaprylyl carbonate, e.g., from about 18% to about 19% of a mixture of diisopropyl sebacate and dicaprylyl carbon
  • the sunscreen composition comprises: the UV-A filter is Butyl methoxydibenzoylmethane, a first UV-B filter is Isoamyl p-methoxycinnamate, a second UV-B filter is octyl salicylate, a third UV-B filter is diethylhexyl butamido triazone, and the broad band UV-A and UV-B filter is bis-ethylhexyloxyphenol methoxyphenyl triazine, wherein the mass ratio of UV-A filter to UV-B filters to broad band filter is about 9 : 25 : 7 and wherein the composition further comprises diisopropyl sebacate and dicaprylyl carbonate, such as from about 17% to about 20% of a mixture of diisopropyl sebacate and dicaprylyl carbonate, e.g., from about 18% to about 19% of a mixture of diisopropyl sebacate and dicap
  • the sunscreen composition comprises: the UV-A filter is Butyl methoxydibenzoylmethane, a first UV-B filter is Ethylhexyl triazone, a second UV-B filter is octyl salicylate, a third UV-B filter is Isoamyl p-methoxycinnamate, and the broad band UV-A and UV-B filter is bis-ethylhexyloxyphenol methoxyphenyl triazine, wherein the mass ratio of UV-A filter to UV-B filters to broad band filter is about 9 : 23 : 8 and wherein the composition further comprises diisopropyl sebacate, dicaprylyl carbonate, and decyl cocoate, such as from about 20% to about 23% of a mixture of diisopropyl sebacate, dicaprylyl carbonate, and decyl cocoate, e.g., from about 21% to about 22% of a mixture of
  • the sunscreen composition comprises: the UV-A filter is Butyl methoxydibenzoylmethane, a first UV-B filter is Isoamyl p-methoxy ci nnam ate, a second UV-B filter is octyl salicylate, a third UV-B filter is diethylhexyl butamido triazone, and the broad band UV-A and UV-B filter is bis-ethylhexyloxyphenol methoxyphenyl triazine, wherein the mass ratio of UV-A filter to UV-B filters to broad band filter is about 9 : 23 : 8 and wherein the composition further comprises diisopropyl sebacate, dicaprylyl carbonate, and decyl cocoate, such as from about 20% to about 23% of a mixture of diisopropyl sebacate, dicaprylyl carbonate, and decyl cocoate, e.g., from about 21% to
  • the sunscreen composition comprises: the UV-A filter is Butyl methoxydibenzoylmethane, a first UV-B filter is Ethylhexyl triazone, a second UV-B filter is octyl salicylate, a third UV-B filter is Isoamyl p-methoxycinnamate, and the broad band UV-A and UV-B filter is bis-ethylhexyloxyphenol methoxyphenyl triazine, wherein the mass ratio of UV-A filter to UV-B filters to broad band filter is about 9 : 18 : 8 and wherein the composition further comprises diisopropyl sebacate, dicaprylyl carbonate, and decyl cocoate, such as from about 24% to about 28% of a mixture of diisopropyl sebacate, dicaprylyl carbonate, and decyl cocoate, e.g., from about 25% to about 27% of a mixture of
  • the sunscreen composition comprises: the UV-A filter is Butyl methoxydibenzoylmethane, a first UV-B filter is Isoamyl p-methoxycinnamate, a second UV-B filter is octyl salicylate, a third UV-B filter is diethylhexyl butamido triazone, and the broad band UV-A and UV-B filter is bis-ethylhexyloxyphenol methoxyphenyl triazine, wherein the mass ratio of UV-A filter to UV-B filters to broad band filter is about 9 : 18 : 8 and wherein the composition further comprises diisopropyl sebacate, dicapiylyl carbonate, and decyl cocoate, such as from about 24% to about 28% of a mixture of diisopropyl sebacate, dicapiylyl carbonate, and decyl cocoate, e.g., from about 25% to about 2
  • the sunscreen composition comprises: the UV-A filter is Butyl methoxydibenzoylmethane, a first UV-B filter is Ethylhexyl triazone, a second UV-B filter is octyl salicylate, a third UV-B filter is Isoamyl p-methoxycinnamate, and the broad band UV-A and UV-B filter is bis-ethylhexyloxyphenol methoxyphenyl triazine, wherein the mass ratio of UV-A filter to UV-B filters to broad band filter is about 9 :
  • composition further comprises diisopropyl sebacate, dicapiylyl carbonate, and decyl cocoate, such as from about 23% to about 26% of a mixture of diisopropyl sebacate, dicapiylyl carbonate, and decyl cocoate, e.g., from about 24% to about 25% of a mixture of diisopropyl sebacate, dicaprylyl carbonate, and decyl cocoate.
  • diisopropyl sebacate such as from about 23% to about 26% of a mixture of diisopropyl sebacate, dicapiylyl carbonate, and decyl cocoate, e.g., from about 24% to about 25% of a mixture of diisopropyl sebacate, dicaprylyl carbonate, and decyl cocoate.
  • the sunscreen composition comprises: the UV-A filter is Butyl methoxydibenzoylmethane, a first UV-B filter is Ethylhexyl triazone, a second UV-B filter is octyl salicylate, a third UV-B filter is diethylhexyl butamido triazone, and the broad band UV-A and UV-B filter is bis-ethylhexyloxyphenol methoxyphenyl triazine, wherein the mass ratio of UV-A filter to UV-B filters to broad band filter is about 9 :
  • composition further comprises dibutyl adipate, and decyl cocoate, such as from about 31% to about 34% of a mixture of dibutyl adipate, and decyl cocoate, e.g., from about 32% to about 33% of a mixture of dibutyl adipate, and decyl cocoate.
  • the sunscreen composition comprises: the UV-A filter is Butyl methoxydibenzoylmethane, a first UV-B filter is Isoamyl p-methoxycinnamate, a second UV-B filter is octyl salicylate, a third UV-B filter is diethylhexyl butamido triazone, and the broad band UV-A and UV-B filter is bis-ethylhexyloxyphenol methoxyphenyl triazine, wherein the mass ratio of UV-A filter to UV-B filters to broad band filter is about 9 :
  • composition further comprises diisopropyl sebacate, dicaprylyl carbonate, and decyl cocoate, such as from about 23% to about 26% of a mixture of diisopropyl sebacate, dicaprylyl carbonate, and decyl cocoate, e.g., from about 24% to about 25% of a mixture of diisopropyl sebacate, dicaprylyl carbonate, and decyl cocoate.
  • diisopropyl sebacate, dicaprylyl carbonate, and decyl cocoate such as from about 23% to about 26% of a mixture of diisopropyl sebacate, dicaprylyl carbonate, and decyl cocoate, e.g., from about 24% to about 25% of a mixture of diisopropyl sebacate, dicaprylyl carbonate, and decyl cocoate.
  • the sunscreen composition comprises: the UV-A filter is Butyl methoxydibenzoylmethane, a first UV-B filter is Ethylhexyl triazone, a second UV-B filter is octyl salicylate, a third UV-B filter is Isoamyl p-methoxycinnamate, and the broad band UV-A and UV-B filter is bis-ethylhexyloxyphenol methoxyphenyl triazine, wherein the mass ratio of UV-A filter to UV-B filters to broad band filter is about 9 : 18 : 8 and wherein the composition further comprises diisopropyl sebacate, decyl cocoate, and diisopropyl adipate, such as from about 25% to about 28% of a mixture of diisopropyl sebacate, decyl cocoate, and diisopropyl adipate, e.g., from about 26% to about 2
  • the sunscreen composition comprises: the UV-A filter is Butyl methoxydibenzoylmethane, a first UV-B filter is Isoamyl p-methoxy ci nnam ate, a second UV-B filter is octyl salicylate, a third UV-B filter is diethylhexyl butamido triazone, and the broad band UV-A and UV-B filter is bis-ethylhexyloxyphenol methoxyphenyl triazine, wherein the mass ratio of UV-A filter to UV-B filters to broad band filter is about 9 : 18 : 8 and wherein the composition further comprises diisopropyl sebacate, decyl cocoate, and diisopropyl adipate, such as from about 25% to about 28% of a mixture of diisopropyl sebacate, decyl cocoate, and diisopropyl adipate, e.g.
  • the sunscreen composition comprises: the UV-A filter is Butyl methoxydibenzoylmethane, a first UV-B filter is Ethylhexyl triazone, a second UV-B filter is octyl salicylate, a third UV-B filter is Isoamyl p-methoxycinnamate, and the broad band UV-A and UV-B filter is bis-ethylhexyloxyphenol methoxyphenyl triazine, wherein the mass ratio of UV-A filter to UV-B filters to broad band filter is about 9 : 16 : 8 and wherein the composition further comprises diisopropyl sebacate, dicaprylyl carbonate, and decyl cocoate, such as from about 24% to about 27% of a mixture of diisopropyl sebacate, dicaprylyl carbonate, and decyl cocoate, e.g., from about 25% to about 26% of a mixture of
  • the sunscreen composition comprises: the UV-A filter is Butyl methoxydibenzoylmethane, a first UV-B filter is Ethylhexyl triazone, a second UV-B filter is octyl salicylate, a third UV-B filter is diethylhexyl butamido triazone, and the broad band UV-A and UV-B filter is bis-ethylhexyloxyphenol methoxyphenyl triazine, wherein the mass ratio of UV-A filter to UV-B filters to broad band filter is about 9 : 14 : 8 and wherein the composition further comprises dibutyl adipate, such as from about 36% to about 39% of dibutyl adipate, e.g., from about 37% to about 38% dibutyl adipate.
  • dibutyl adipate such as from about 36% to about 39% of dibutyl adipate, e.g., from about 37% to about
  • the sunscreen composition comprises: the UV-A filter is Butyl methoxydibenzoylmethane, a first UV-B filter is Isoamyl p-methoxy ci nnam ate, a second UV-B filter is octyl salicylate, a third UV-B filter is diethylhexyl butamido triazone, and the broad band UV-A and UV-B filter is bis-ethylhexyloxyphenol methoxyphenyl triazine, wherein the mass ratio of UV-A filter to UV-B filters to broad band filter is about 9 : 16 : 8 and wherein the composition further comprises diisopropyl sebacate, dicaprylyl carbonate, and decyl cocoate, such as from about 24% to about 27% of a mixture of diisopropyl sebacate, dicaprylyl carbonate, and decyl cocoate, e.g., from about 25% to
  • the sunscreen composition comprises: the UV-A filter is Butyl methoxydibenzoylmethane, a first UV-B filter is Ethylhexyl triazone, a second UV-B filter is octyl salicylate, a third UV-B filter is Isoamyl p-methoxycinnamate, and the broad band UV-A and UV-B filter is bis-ethylhexyloxyphenol methoxyphenyl triazine, wherein the mass ratio of UV-A filter to UV-B filters to broad band filter is about 9 : 16 : 8 and wherein the composition further comprises diisopropyl sebacate, dicaprylyl carbonate, and decyl cocoate, such as from about 25% to about 28% of a mixture of diisopropyl sebacate, dicaprylyl carbonate, and decyl cocoate, e.g., from about 26% to about 27% of a mixture of
  • the sunscreen composition comprises: the UV-A filter is Butyl methoxydibenzoylmethane, a first UV-B filter is Ethylhexyl triazone, a second UV-B filter is octyl salicylate, a third UV-B filter is diethylhexyl butamido triazone, and the broad band UV-A and UV-B filter is bis-ethylhexyloxyphenol methoxyphenyl triazine, wherein the mass ratio of UV-A filter to UV-B filters to broad band filter is about 9 : 14 : 8 and wherein the composition further comprises dibutyl adipate, and decyl cocoate, such as from about 31% to about 34% of a mixture of dibutyl adipate, and decyl cocoate, e.g., from about 32% to about 33% of a mixture of dibutyl adipate, and decyl cocoate.
  • the UV-A filter is But
  • the sunscreen composition comprises: the UV-A filter is Butyl methoxydibenzoylmethane, a first UV-B filter is Isoamyl p-methoxycinnamate, a second UV-B filter is octyl salicylate, a third UV-B filter is diethylhexyl butamido triazone, and the broad band UV-A and UV-B filter is bis-ethylhexyloxyphenol methoxyphenyl triazine, wherein the mass ratio of UV-A filter to UV-B filters to broad band filter is about 9 : 15 : 8 and wherein the composition further comprises diisopropyl sebacate, dicaprylyl carbonate, and decyl cocoate, such as from about 25% to about 28% of a mixture of diisopropyl sebacate, dicaprylyl carbonate, and decyl cocoate, e.g., from about 26% to about 27% of
  • the sunscreen composition is an emulsion. In certain embodiments, the composition is an oil-in-water emulsion. In certain embodiments, the composition is a water-in-oil emulsion. In certain embodiments, the sunscreen composition is a spray. In certain embodiments, the sunscreen composition is an oil. In certain embodiments, the sunscreen composition is a lotion. In certain embodiments, the sunscreen composition is a cream. In certain embodiments, the sunscreen composition is a gel. In certain embodiments, the sunscreen composition is a butter. In certain embodiments, the sunscreen composition is a paste. In certain embodiments, the sunscreen composition is an ointment. In certain embodiments, the sunscreen composition is a stick. In certain embodiments, the sunscreen composition is a powder.
  • the sunscreen composition is a wipe. In certain embodiments, the sunscreen composition is a towelette. In certain embodiments, the sunscreen composition is a body wash. In certain embodiments, the sunscreen composition is a shampoo. In certain embodiments, the sunscreen composition is a mist. In certain embodiments, the sunscreen composition is a poured compact. In certain embodiments, the sunscreen composition is a solution. In certain embodiments, the sunscreen composition is an ointment. In certain embodiments, the sunscreen composition is a liquid. In certain embodiments, the sunscreen composition is a solid. In certain embodiments, the sunscreen composition is a milk. In certain embodiments, the sunscreen composition is a suspension. In certain embodiments, the sunscreen composition is a microemulsion.
  • the sunscreen composition is a dispersion. In certain embodiments, the sunscreen composition is a microencapsulated product. In certain embodiments, the sunscreen composition is a balm. In certain embodiments, the sunscreen composition is a tonic. In certain embodiments, the sunscreen composition is a paste. In certain embodiments, the sunscreen composition is a peel. In certain embodiments, the sunscreen composition is a soap. In certain embodiments, the sunscreen composition is an aerosol. In certain embodiments, the sunscreen composition is a mousse. In certain embodiments, the sunscreen composition is a wax. In certain embodiments, the sunscreen composition is a pomade. In certain embodiments, the sunscreen composition is a spritz. In certain embodiments, the sunscreen composition is a laquer.
  • the sunscreen composition is a serum. In certain embodiments, the sunscreen composition is a powder. In certain embodiments, the sunscreen composition is a pencil. In certain embodiments, the sunscreen composition is a blush. In certain embodiments, the sunscreen composition is a highlighter. In certain embodiments, the sunscreen composition is a bronzer. In certain embodiments, the sunscreen composition is a concealer.
  • the vehicle may comprise an aqueous phase, an oil phase, an alcohol, a silicone phase or mixtures thereof.
  • the cosmetically acceptable vehicle may also comprise an emulsion.
  • suitable emulsions include water-in-oil emulsions, oil- in-water emulsions, silicone-in-water emulsions, water-in-silicone emulsions, wax-in-water emulsions, water-oil-water triple emulsions or the like having the appearance of a cream, gel or microemulsions.
  • the emulsion may include an emulsifier, such as a nonionic, anionic or amphoteric surfactant.
  • the oil phase of the emulsion in one embodiment has one or more organic compounds, including emollients; humectants (such as butylene glycol, propylene glycol, Methyl gluceth-20, and glycerin); other water-dispersible or water-soluble components including thickeners such as veegum or hydroxy alkyl cellulose; gelling agents, such as high MW polyacrylic acid, i.e. CARBOPOL 934; and mixtures thereof.
  • the emulsion may have one or more emulsifiers capable of emulsifying the various components present in the composition.
  • the compounds suitable for use in the oil phase include without limitation, vegetable oils; esters such as octyl palmitate, isopropyl myristate and isopropyl palmitate; ethers such as dicapiyl ether; fatty alcohols such as cetyl alcohol, stearyl alcohol and behenyl alcohol; isoparaffins such as isooctane, isododecane and isohexadecane; silicone oils such as dimethicones, cyclic silicones, and polysiloxanes; hydrocarbon oils such as mineral oil, petrolatum, isoeicosane and polyisobutene; natural or synthetic waxes; and the like. Suitable hydrophobic hydrocarbon oils may be saturated or unsaturated, have an aliphatic character and be straight or branched chained or contain alicyclic or aromatic rings.
  • the oil-containing phase may be composed of a singular oil or mixtures of different oils.
  • Hydrocarbon oils include those having 6-20 carbon atoms, more in one embodiment 10-16 carbon atoms.
  • Representative hydrocarbons include decane, dodecane, tetradecane, tri decane, and C8-2o isoparaffins.
  • Paraffinic hydrocarbons are available from Exxon under the ISOPARS trademark, and from the Permethyl Corporation.
  • C8-2o paraffinic hydrocarbons such as C12 isoparaffin (isododecane) manufactured by the Permethyl Corporation having the tradename Permethyl 99A.TM. are also contemplated to be suitable.
  • Ci6 isoparaffins such as isohexadecane (having the tradename Permethyl) are also suitable.
  • volatile hydrocarbons examples include polydecanes such as isododecane and isodecane, including for example, Permethyl-99A (Presperse Inc.) and the C7-C8 through C12-C15 isoparaffins such as the Isopar Series available from Exxon Chemicals.
  • a representative hydrocarbon solvent is isododecane.
  • the oil phase may comprise one or more waxes, including for example, rice bran wax, camauba wax, ouri curry wax, candelilla wax, montan waxes, sugar cane waxes, ozokerite, polyethylene waxes, Fischer-Tropsch waxes, beeswax, microcrystalline wax, silicone waxes, fluorinated waxes, and any combination thereof.
  • waxes including for example, rice bran wax, camauba wax, ouri curry wax, candelilla wax, montan waxes, sugar cane waxes, ozokerite, polyethylene waxes, Fischer-Tropsch waxes, beeswax, microcrystalline wax, silicone waxes, fluorinated waxes, and any combination thereof.
  • Non-limiting emulsifiers include emulsifying waxes, emulsifying polyhydric alcohols, polyether polyols, polyethers, mono- or di-ester of polyols, ethylene glycol mono- stearates, glycerin mono-stearates, glycerin di-stearates, silicone-containing emulsifiers, soya sterols, fatty alcohols such as cetyl alcohol, acrylates, fatty acids such as stearic acid, fatty acid salts, and mixtures thereof.
  • emulsifiers include soya sterol, cetyl alcohol, stearic acid, emulsifying wax, acrylates, silicone containing emulsifiers and mixtures thereof.
  • Other specific emulsifiers that can be used in the composition of the present invention include, but are not limited to, one or more of the following: Cto-30 alkyl acrylate crosspolymer; Dimethicone PEG-7 isostearate, acrylamide copolymer; mineral oil; sorbitan esters; poly glyceryl-3 -diisostearate; sorbitan monostearate, sorbitan tristearate, sorbitan sesquioleate, sorbitan monooleate; glycerol esters such as glycerol monostearate and glycerol monooleate; polyoxyethylene phenols such as polyoxyethylene octyl phenol and polyoxyethylene nonyl phenol; polyoxyethylene ethers such as polyoxyethylene cety
  • the oil phase may comprise one or more volatile and/or non-volatile silicone oils.
  • Volatile silicones include cyclic and linear volatile dimethylsiloxane silicones.
  • the volatile silicones may include cyclodimethicones, including tetramer (D*), pentamer (D5), and hexamer (D6) cyclomethicones, or mixtures thereof. Particular mention may be made of the volatile cyclomethicone-hexamethyl cyclotrisiloxane, octamethyl- cyclotetrasiloxane, and decamethyl-cyclopentasiloxane.
  • Suitable dimethicones are available from Dow Coming under the name Dow Coming 200 Fluid and have viscosities ranging from 0.65 to 600,000 centistokes or higher.
  • Suitable non-polar, volatile liquid silicone oils are disclosed in U.S. Pat. No. 4,781,917, herein incorporated by reference in its entirety. Additional volatile silicones materials are described in Todd et al., "Volatile Silicone Fluids for Cosmetics", Cosmetics and Toiletries, 91 :27-32 (1976), herein incorporated by reference in its entirety. Linear volatile silicones generally have a viscosity of less than about 5 centistokes at 25° C, whereas the cyclic silicones have viscosities of less than about 10 centistokes at 25° C.
  • volatile silicones of varying viscosities include Dow Coming 200, Dow Coming 244, Dow Coming 245, Dow Coming 344, and Dow Coming 345, (Dow Coming Corp.); SF-1204 and SF-1202 Silicone Fluids (G.E. Silicones), GE 7207 and 7158 (General Electric Co.); and SWS-03314 (SWS Silicones Corp.).
  • Linear, volatile silicones include low molecular weight polydimethylsiloxane compounds such as hexamethyldisiloxane, octamethyltrisiloxane, decamethyltetrasiloxane, and dodecamethylpentasiloxane, to name a few.
  • Non-volatile silicone oils will typically comprise polyalkylsiloxanes, polyarylsiloxanes, polyalkylarylsiloxanes, or mixtures thereof. Polydimethylsiloxanes are in one embodiment non-volatile silicone oils. The non-volatile silicone oils will typically have a viscosity from about 10 to about 60,000 centistokes at 25° C, in one embodiment between about 10 and about 10,000 centistokes, and more in one embodiment still between about 10 and about 500 centistokes; and a boiling point greater than 250° C at atmospheric pressure.
  • Non limiting examples include dimethyl polysiloxane (dimethicone), phenyl trimethicone, and diphenyldimethicone.
  • volatile and non-volatile silicone oils may optionally be substituted with various functional groups such as alkyl, aryl, amine groups, vinyl, hydroxyl, haloalkyl groups, alkylaryl groups, and acrylate groups, to name a few.
  • the water-in-silicone emulsion may be emulsified with a nonionic surfactant (emulsifier) such as, for example, polydiorganosiloxane-polyoxyalkylene block copolymers, including those described in U.S. Pat. No. 4,122,029, the disclosure of which is hereby incorporated by reference.
  • a nonionic surfactant emulsifier
  • polydiorganosiloxane-polyoxyalkylene block copolymers including those described in U.S. Pat. No. 4,122,029, the disclosure of which is hereby incorporated by reference.
  • emulsifiers generally comprise a polydiorganosiloxane backbone, typically polydimethylsiloxane, having side chains comprising -(EO)m- and/or - (PO)n- groups, where EO is ethyleneoxy and PO is 1,2-propyleneoxy, the side chains being typically capped or terminated with hydrogen or lower alkyl groups (e.g., Ct-6, typically C 1 -3).
  • EO ethyleneoxy
  • PO 1,2-propyleneoxy
  • Other suitable water-in-silicone emulsifiers are disclosed in U.S. Pat. No. 6,685,952, the disclosure of which is hereby incorporated by reference herein.
  • water-in-silicone emulsifiers include those available from Dow Coming under the trade designations 3225C and 5225C FORMULATION AID; SILICONE SF-1528 available from General Electric; ABIL EM 90 and EM 97, available from Goldschmidt Chemical Corporation (Hopewell, Va.); and the SILWET series of emulsifiers sold by OSI Specialties (Danbury, Conn.).
  • water-in-silicone emulsifiers include, but are not limited to, dimethicone PEG 10/15 crosspolymer, dimethicone copolyol, cetyl dimethicone copolyol, PEG- 15 lauryl dimethicone crosspolymer, lamylmethicone crosspolymer, cyclomethicone and dimethicone copolyol, dimethicone copolyol (and) caprylic/capric triglycerides, polyglyceryl-4 isostearate (and) cetyl dimethicone copolyol (and) hexyl laurate, and dimethicone copolyol (and) cyclopentasiloxane.
  • examples of water-in- silicone emulsifiers include, without limitation, PEG/PPG-18/18 dimethicone (trade name 5225C, Dow Coming), PEG/PPG-19/19 dimethicone (trade name BY25-337, Dow Coming), Cetyl PEG/PPG- 10/1 dimethicone (trade name Abil EM-90, Goldschmidt Chemical Corporation), PEG-12 dimethicone (trade name SF 1288, General Electric), lauryl PEG/PPG- 18/18 methicone (trade name 5200 FORMULATION AID, Dow Coming), PEG-12 dimethicone crosspolymer (trade name 9010 and 9011 silicone elastomer blend, Dow Coming), PEG-10 dimethicone crosspolymer (trade name KSG-20, Shin-Etsu), dimethicone PEG-10/15 crosspolymer (trade name KSG-210, Shin-Etsu), and dimethicone PEG-7 isostearate.
  • the water-in-silicone emulsifiers typically will be present in the composition in an amount from about 0.001% to about 10% by weight, in particular in an amount from about 0.01% to about 5% by weight, and more in one embodiment, below 1% by weight.
  • the aqueous phase of the emulsion may include one or more additional solvents, including lower alcohols, such as ethanol, isopropanol, and the like.
  • the volatile solvent may also be a cosmetically acceptable ester such as butyl acetate or ethyl acetate; ketones such as acetone or ethyl methyl ketone; or the like.
  • the oil-containing phase will typically comprise from about 10% to about 99%, in one embodiment from about 20% to about 85%, and more in one embodiment from about 30% to about 70% by weight, based on the total weight of the emulsion, and the aqueous phase will typically comprise from about 1% to about 90%, in one embodiment from about 5% to about 70%, and more in one embodiment from about 20% to about 60% by weight of the total emulsion.
  • the aqueous phase will typically comprise from about 25% to about 100%, more typically from about 50% to about 95% by weight water.
  • the compositions may include liposomes.
  • the liposomes may comprise other additives or substances and/or may be modified to more specifically reach or remain at a site following administration.
  • composition may optionally comprise other cosmetic actives and excipients, obvious to those skilled in the art including, but not limited to, fillers, emulsifying agents, antioxidants, surfactants, film formers, chelating agents, gelling agents, thickeners, emollients, humectants, moisturizers, vitamins, minerals, viscosity and/or rheology modifiers, sunscreens, keratolytics, depigmenting agents, retinoids, hormonal compounds, alpha- hydroxy acids, alpha-keto acids, anti-mycobacterial agents, antifungal agents, antimicrobials, antivirals, analgesics, lipidic compounds, anti-allergenic agents, HI or H2 antihistamines, anti-inflammatory agents, anti-irritants, antineoplastics, immune system boosting agents, immune system suppressing agents, anti-acne agents, anesthetics, antiseptics, insect repellents, skin cooling compounds, skin protectants, skin penetration enhance
  • film formers include a poly CIO-30 alkyl acrylate as well as a trimethylpentanediol/ adipic acid / glycerin crosspolymer.
  • the sunscreen composition may also include other cosmetic ingredients such as, but not limited to, humectants, emollients, moisturizers, antiwrinkle ingredients, concealors, matte finishing agents, pigments, colorants, proteins, antioxidants, bronzers, chelating agents, emulsifiers, ultraviolet (UV) absorbing agents, oil absorbing agents, anti-foam agents, anti-tack agents, thickeners, fragrances, preservatives, anti-microbials, fungistats, neutralizing agents, vitamins, plasticizers, cohesion agents, basifying and acidifying agents, fillers, solvents, and mixtures thereof.
  • other cosmetic ingredients such as, but not limited to, humectants, emollients, moisturizers, antiwrinkle ingredients, concealors, matte finishing agents, pigments, colorants, proteins, antioxidants, bronzers, chelating agents, emulsifiers, ultraviolet (UV) absorbing agents, oil absorbing agents, anti-foam agents, anti-t
  • compositions may contain additional ingredients such as alkalinizing agents, emulsifying agents, emollients, plasticizers, preservatives, humectants, moisturizing agents, solvents, and tonicity agents or active ingredients suitable to provide anti-aging benefits.
  • additional ingredients include glycerin.
  • Viscosifying agents such as gellants may also be used.
  • the composition may also contain at least one cosmetic active ingredient and/or at least one dermatological active ingredient, i.e. an agent having a beneficial effect on the skin. The loading of such active ingredient can be achieved in any means known to those skilled in the art.
  • the composition may comprise further comprise other whitening or lightening agents that either hide the discoloration with pigments or other light-reflecting materials, or treat the cause of the discoloration.
  • the sunscreen composition is substantially stable to sunlight.
  • the AUC in the spectral absorption spectrum after irradiation with a solar simulator is at least 80% of the AUC in the spectral absorption spectrum prior to irradiation.
  • the AUC in the spectral absorption spectrum after irradiation with a solar simulator is at least 90% of the AUC in the spectral absorption spectrum prior to irradiation.
  • Sunlight stability can be measured by methods known to those of skill in the art.
  • the sunscreen composition is substantially water resistant. Water resistance can be measured by methods known to those of skill in the art.
  • the composition is water resistant for 40 or 80 minutes as codified by the US Food and Drug Administration at Section 201.327(i)(7) of Volume 21 of the Code of Federal Regulations (2019).
  • the sunscreen composition is phase stable.
  • Phase stability means the maintenance of interfacial stability or suspension stability or both at each of the temperatures 4°C, 32-37°C, 40-45°C, 25°C for at least 4 weeks.
  • Interfacial stability refers to stability against coalescence and coarsening of a discontinuous phase in a composition having two or more phases.
  • “Suspension stability” refers to stability against creaming and/or sedimentation of a discontinuous phase, for example solids, suspended in continuous phase.
  • the sunscreen composition maintains both interfacial stability and suspension stability at each of the temperatures 4°C, 32-37°C, 40-45°C, 25°C for at least 4 weeks.
  • the composition may be filled into an appropriately sized vessel where it is fully visible, such as a clear 4 oz. glass jar.
  • the interfacial stability of the sunscreen composition can be assessed visually and is considered unstable if at least two distinct, immiscible phases of the composition are observed, as well known in the art.
  • the sunscreen composition is not phase stable and, e.g., is shaken before use.
  • the suspension stability of the sunscreen composition can be assessed visually or tactilely and is considered unstable if a distinct separation or gradient in color, opacity, grittiness, or other indicator of non-uniformity between different regions in a sample (i.e., top and bottom, or other different regions) is observed.
  • the suspension stability of the composition can alternatively be assessed through, but not limited to, Brookfield viscosity and is considered unstable if there are significant changes in viscosity measurement (5 or 10 or 20% for example) between different regions in a sample (i.e., top and bottom or other different regions). Brookfield viscosity may be measured with a Brookfield Laboratory Viscometer from AMETEK Inc.
  • the sunscreen composition can be used by topically applying to the skin.
  • the method for application can include the direct spraying, laying on, wiping or spreading of the composition on the skin.
  • the sunscreen composition may be prepared using mixing and blending methodology well established in the sunscreen and cosmetic art.
  • the composition is produced by preparing an oil phase by mixing the UV-absorbing compounds with optional oil soluble or oil-miscible ingredients; and preparing a water phase, by mixing water and optional water-soluble or water-miscible ingredients.
  • the oil phase and the water phase may then be mixed in a manner sufficient to disperse the oil phase substantially homogeneously in the water phase such that the water phase is continuous and the oil phase discontinuous.
  • the percentage by weight of water phase included in the compositions may range from about 30% to about 85% such as from about 35% to about 75%, such as from about 40% to about 70%.
  • the percentage by weight of water in the water phase may be about 60% or more, such as about 70% or more, such as about 90% or more.
  • the composition may be combined with a “cosmetically-acceptable topical carrier,” i.e., a carrier for topical use that capable of containing the other ingredients dispersed or dissolved therein, and possessing acceptable properties rendering it safe to use topically.
  • the cosmetically-acceptable topical carrier may optionally comprise a wide variety of additional oil-soluble materials and/or water-soluble materials conventionally used in compositions for use on skin, at their art-established levels.
  • additional oil-soluble materials and/or water-soluble materials conventionally used in compositions for use on skin, at their art-established levels.
  • the composition includes a pigment suitable for providing color or hiding power.
  • the pigment may be one suitable for use in a color cosmetic product, including compositions for application to the hair, nails and/or skin, especially the face.
  • Color cosmetic compositions include, but are not limited to, foundations, concealers, primers, blush, mascara, eyeshadow, eyeliner, lipstick, nail polish and tinted moisturizers.
  • the pigment suitable for providing color or hiding power may be composed of iron oxides, including red and yellow iron oxides, titanium dioxide, ultramarine and chromium or chromium hydroxide colors, and mixtures thereof.
  • the pigment may be a lake pigment, e.g.
  • an organic dye such as azo, indigoid, triphenylmethane, anthraquinone, and xanthine dyes that are designated as D&C and FD&C blues, browns, greens, oranges, reds, yellows, etc., precipitated onto inert binders such as insoluble salts.
  • lake pigments include Red #6, Red #7, Yellow #5, Violet #2 and Blue #1.
  • the pigment may be an interference pigment.
  • interference pigments include those containing mica substrates, bismuth oxycloride substrates, and silica substrates, for instance mica/bismuth oxychloride/iron oxide pigments commercially available as CHROMALITE pigments (BASF), titanium dioxide and/or iron oxides coated onto mica such as commercially available FLAMENCO pigments (BASF), mica/titanium dioxide/iron oxide pigments including commercially available KTZ pigments (Kobo products), CELLINI pearl pigments (BASF), and borosilicate-containing pigments such as REFLECKS pigments (BASF).
  • BASF commercially available FLAMENCO pigments
  • mica/titanium dioxide/iron oxide pigments including commercially available KTZ pigments (Kobo products), CELLINI pearl pigments (BASF), and borosilicate-containing pigments such as REFLECKS pigments (BASF).
  • the composition comprises a humectant such as glycols, glycerin or propanediol.
  • a humectant such as glycols, glycerin or propanediol.
  • the composition may comprise for example at least about 1.0 weight percent of a humectant.
  • the composition may further comprise one or more other cosmetically acceptable active agents include for example anti-acne agents, shine control agents, anti-microbial agents, anti-mycotic agents, anti-parasite agents (including anti-mosquito agents), external analgesics, antioxidants, moisturizers, nutrients, vitamins, energy enhancers, anti-perspiration agents, astringents, deodorants, firming agents, anti-callous agents, and agents for skin conditioning, tanning agent, anti-wrinkles and anti-dark spots.
  • the composition is intended for use as a non-therapeutic treatment.
  • the composition is an article intended to be rubbed, poured, sprinkled, or sprayed on, introduced into, or otherwise applied to the human body for cleansing, beautifying, promoting attractiveness, or altering the appearance, in accordance with the US FD&C Act, ⁇ 201(i).
  • the amount of other cosmetically active agents may range from about 0.001% to about 20% by weight of the composition, e.g., about 0.005% to about 10% by weight of the composition, such as about 0.01% to about 5% by weight of the composition.
  • the sunscreen formulations described herein are eco- compatable compositions.
  • the sunscreen formulations are compatible with organism life and not harmful to marine ecosystems (in particular for tropical environments with coral reefs).
  • the sunscreen formulaitons are free of components that inhibit cell growth or cell replication in a marine environment.
  • sunscreen formulations being free of bis ethylhexyloxyphenol methoxyphenyl triazine (BEMT), cinnamates, benzophenones, camphor derivatives, titanium oxide, melaleuca essential oil, ylang ylang flower extracts, Bambousa Arundinacea extracts, Karite, animal-derived fats, argan oil, ocopheiyl acetate, tocopherol, retinol, polyphenolic compounds extracted from green tea or mixtures thereof.
  • BEMT bis ethylhexyloxyphenol methoxyphenyl triazine
  • cinnamates benzophenones
  • camphor derivatives titanium oxide
  • melaleuca essential oil melaleuca essential oil
  • ylang ylang flower extracts Bambousa Arundinacea extracts
  • Karite animal-derived fats
  • argan oil ocopheiyl acetate
  • tocopherol retinol
  • the sunscreen formulations can include diisopropyl sebacate, dimethylmethoxy chromanol, gluconolactone, potassium sorbate, dimethylmethoxy chromanol, decyl cocoate, pentylene glycol, dimethicone, hydrolyzed citrus aurantium dulcis fruit extract
  • Aspect 1 provides a UV filter composition comprising: three UV-B filters; a UV-A filter; and a UV-A + UV-B broadband filter.
  • Aspect 2 provides a sunscreen composition comprising a UV filter composition of
  • Aspect 3 provides the sunscreen composition of Aspect 2, further comprising one or more solubilizers.
  • Aspect 4 provides the sunscreen composition of Aspect 3, wherein the one or more solubilizers are chosen from diisopropyl sebacate, dicaprylyl carbonate, decyl cocoate, diisopropyl adipate, isopropyl lauroyl sarcosinate, dibutyl adipate, butyloctyl salicylate, C12- 15 alkyl benzoate, and diethylhexyl succinate.
  • the one or more solubilizers are chosen from diisopropyl sebacate, dicaprylyl carbonate, decyl cocoate, diisopropyl adipate, isopropyl lauroyl sarcosinate, dibutyl adipate, butyloctyl salicylate, C12- 15 alkyl benzoate, and diethylhexyl succinate.
  • Aspect 5 provides the sunscreen composition of any one of Aspects 2 to 4, wherein: the UV-A filter is Butyl methoxydibenzoylmethane, a first UV-B filter is Ethylhexyl triazone, a second UV-B filter is octyl salicylate, a third UV-B filter is Isoamyl p-methoxycinnamate, and the broad band UV-A and UV-B filter is bis-ethylhexyloxyphenol methoxyphenyl triazine.
  • the UV-A filter is Butyl methoxydibenzoylmethane
  • a first UV-B filter is Ethylhexyl triazone
  • a second UV-B filter is octyl salicylate
  • a third UV-B filter is Isoamyl p-methoxycinnamate
  • the broad band UV-A and UV-B filter is bis-ethylhexyl
  • Aspect 6 provides the sunscreen composition of Aspect 5, wherein the UV-A filter is Butyl methoxy dibenzoylmethane, a first UV-B filter is Ethylhexyl triazone, a second UV-B filter is octyl salicylate, a third UV-B filter is Isoamyl p-methoxycinnamate, and the broad band UV-A and UV-B filter is bis-ethylhexyloxyphenol methoxyphenyl triazine, wherein the mass ratio of UV-A filter to UV-B filters to broad band filter is about 2 :
  • Aspect 7 provides the sunscreen composition of Aspect 5, wherein the UV-A filter is Butyl m ethoxy dibenzoylmethane, a first UV-B filter is Ethylhexyl triazone, a second UV-B filter is octyl salicylate, a third UV-B filter is Isoamyl p-methoxycinnamate, and the broad band UV-A and UV-B filter is bis-ethylhexyloxyphenol methoxyphenyl triazine, wherein the mass ratio of UV-A filter to UV-B filters to broad band filter is about 4 :
  • Aspect 8 provides the sunscreen composition of Aspect 5, wherein the UV-A filter is Butyl methoxy dibenzoylmethane, a first UV-B filter is Ethylhexyl triazone, a second UV-B filter is octyl salicylate, a third UV-B filter is Isoamyl p-methoxycinnamate, and the broad band UV-A and UV-B filter is bis-ethylhexyloxyphenol methoxyphenyl triazine, wherein the mass ratio of UV-A filter to UV-B filters to broad band filter is about 4 :
  • Aspect 9 provides the sunscreen composition of any one of Aspects 2 to 4, wherein: the UV-A filter is Butyl methoxydibenzoylmethane, a first UV-B filter is Ethylhexyl triazone, a second UV-B filter is octyl salicylate, a third UV-B filter is diethylhexyl butamido triazone, and the broad band UV-A and UV-B filter is bis-ethylhexyloxyphenol methoxyphenyl triazine.
  • the UV-A filter is Butyl methoxydibenzoylmethane
  • a first UV-B filter is Ethylhexyl triazone
  • a second UV-B filter is octyl salicylate
  • a third UV-B filter is diethylhexyl butamido triazone
  • the broad band UV-A and UV-B filter is bis-ethylhexyloxyphenol
  • Aspect 10 provides the sunscreen composition of Aspect 9, wherein the UV-A filter is Butyl methoxydibenzoylmethane, a first UV-B filter is Ethylhexyl triazone, a second UV-B filter is octyl salicylate, a third UV-B filter is diethylhexyl butamido triazone, and the broad band UV-A and UV-B filter is bis-ethylhexyloxyphenol methoxyphenyl triazine, wherein the mass ratio of UV-A filter to UV-B filters to broad band filter is about 2 : 5.5 : 1.
  • Aspect 11 provides the sunscreen composition of Aspect 9, wherein the UV-A filter is Butyl methoxydibenzoylmethane, a first UV-B filter is Ethylhexyl triazone, a second UV-B filter is octyl salicylate, a third UV-B filter is diethylhexyl butamido triazone, and the broad band UV-A and UV-B filter is bis-ethylhexyloxyphenol methoxyphenyl triazine, wherein the mass ratio of UV-A filter to UV-B filters to broad band filter is about 4 :
  • Aspect 12 provides the sunscreen composition of Aspect 9, wherein the UV-A filter is Butyl methoxydibenzoylmethane, a first UV-B filter is Ethylhexyl triazone, a second UV-B filter is octyl salicylate, a third UV-B filter is diethylhexyl butamido triazone, and the broad band UV-A and UV-B filter is bis-ethylhexyloxyphenol methoxyphenyl triazine, wherein the mass ratio of UV-A filter to UV-B filters to broad band filter is about 4 :
  • Aspect 13 provides the sunscreen composition of any one of Aspects 2 to 4, wherein: the UV-A filter is Butyl methoxydibenzoylmethane, a first UV-B filter is Isoamyl p-methoxycinnamate, a second UV-B filter is octyl salicylate, a third UV-B filter is diethylhexyl butamido triazone, and the broad band UV-A and UV-B filter is bis-ethylhexyloxyphenol methoxyphenyl triazine.
  • the UV-A filter is Butyl methoxydibenzoylmethane
  • a first UV-B filter is Isoamyl p-methoxycinnamate
  • a second UV-B filter is octyl salicylate
  • a third UV-B filter is diethylhexyl butamido triazone
  • the broad band UV-A and UV-B filter is bis-
  • Aspect 14 provides the sunscreen composition of Aspect 13, wherein the UV-A filter is Butyl methoxydibenzoylmethane, a first UV-B filter is Isoamyl p-methoxycinnamate, a second UV-B filter is octyl salicylate, a third UV-B filter is diethylhexyl butamido triazone, and the broad band UV-A and UV-B filter is bis-ethylhexyloxyphenol methoxyphenyl triazine, wherein the mass ratio of UV-A filter to UV-B filters to broad band filter is about 2 :
  • Aspect 15 provides the sunscreen composition of Aspect 13, wherein the UV-A filter is Butyl methoxydibenzoylmethane, a first UV-B filter is Isoamyl p-methoxycinnamate, a second UV-B filter is octyl salicylate, a third UV-B filter is diethylhexyl butamido triazone, and the broad band UV-A and UV-B filter is bis-ethylhexyloxyphenol methoxyphenyl triazine, wherein the mass ratio of UV-A filter to UV-B filters to broad band filter is about 1 : 3 : 1.
  • Aspect 16 provides the sunscreen composition of Aspect 13, wherein the UV-A filter is Butyl methoxydibenzoylmethane, a first UV-B filter is Isoamyl p-methoxycinnamate, a second UV-B filter is octyl salicylate, a third UV-B filter is diethylhexyl butamido triazone, and the broad band UV-A and UV-B filter is bis-ethylhexyloxyphenol methoxyphenyl triazine, wherein the mass ratio of UV-A filter to UV-B filters to broad band filter is about 4 :
  • Aspect 17 provides the sunscreen composition of any one of Aspects 2 to 16, wherein the one or more solubilizers is diisopropyl sebacate.
  • Aspect 18 provides the sunscreen composition of Aspect 17, wherein the composition comprises from about 8% to about 10% of diisopropyl sebacate.
  • Aspect 19 provides the sunscreen composition of Aspect 18, wherein the composition comprises from about 6% to about 8% of diisopropyl sebacate.
  • Aspect 20 provides the sunscreen composition of Aspect 5, wherein the UV-A filter is Butyl methoxydibenzoylmethane, a first UV-B filter is Ethylhexyl triazone, a second UV-B filter is octyl salicylate, a third UV-B filter is Isoamyl p-methoxycinnamate, and the broad band UV-A and UV-B filter is bis-ethylhexyloxyphenol methoxyphenyl triazine, wherein the mass ratio of UV-A filter to UV-B filters to broad band filter is about 6 : 17 : 4.
  • Aspect 21 provides the sunscreen composition of Aspect 9, wherein the UV-A filter is Butyl methoxydibenzoylmethane, a first UV-B filter is Ethylhexyl triazone, a second UV-B filter is octyl salicylate, a third UV-B filter is diethylhexyl butamido triazone, and the broad band UV-A and UV-B filter is bis-ethylhexyloxyphenol methoxyphenyl triazine, wherein the mass ratio of UV-A filter to UV-B filters to broad band filter is about 6 : 17 : 4.
  • Aspect 22 provides the sunscreen composition of Aspect 13, wherein the UV-A filter is Butyl methoxydibenzoylmethane, a first UV-B filter is Isoamyl p-methoxycinnamate, a second UV-B filter is octyl salicylate, a third UV-B filter is diethylhexyl butamido triazone, and the broad band UV-A and UV-B filter is bis-ethylhexyloxyphenol methoxyphenyl triazine, wherein the mass ratio of UV-A filter to UV-B filters to broad band filter is about 6 : 17 : 4.
  • Aspect 23 provides the sunscreen composition of any one of Aspects 22 to 24, wherein the one or more solubilizers are diisopropyl sebacate and dicaprylyl carbonate.
  • Aspect 24 provides the sunscreen composition of Aspect 25, wherein the composition comprises from about 13% to about 15.5% of a mixture of diisopropyl sebacate and dicaprylyl carbonate.
  • Aspect 25 provides the sunscreen composition of Aspect 26, wherein the composition comprises from about 13.5% to about 15% of a mixture of diisopropyl sebacate and dicaprylyl carbonate.
  • Aspect 26 provides the sunscreen composition of Aspect 5, wherein the UV-A filter is Butyl methoxydibenzoylmethane, a first UV-B filter is Ethylhexyl triazone, a second UV-B filter is octyl salicylate, a third UV-B filter is Isoamyl p-methoxycinnamate, and the broad band UV-A and UV-B filter is bis-ethylhexyloxyphenol methoxyphenyl triazine, wherein the mass ratio of UV-A filter to UV-B filters to broad band filter is about 7 :
  • Aspect 27 provides the sunscreen composition of Aspect 9, wherein the UV-A filter is Butyl methoxydibenzoylmethane, a first UV-B filter is Ethylhexyl triazone, a second UV-B filter is octyl salicylate, a third UV-B filter is diethylhexyl butamido triazone, and the broad band UV-A and UV-B filter is bis-ethylhexyloxyphenol methoxyphenyl triazine, wherein the mass ratio of UV-A filter to UV-B filters to broad band filter is about 7 :
  • Aspect 28 provides the sunscreen composition of Aspect 13, wherein the UV-A filter is Butyl methoxydibenzoylmethane, a first UV-B filter is Isoamyl p-methoxycinnamate, a second UV-B filter is octyl salicylate, a third UV-B filter is diethylhexyl butamido triazone, and the broad band UV-A and UV-B filter is bis-ethylhexyloxyphenol methoxyphenyl triazine, wherein the mass ratio of UV-A filter to UV-B filters to broad band filter is about 7 : 13 : 6.
  • Aspect 29 provides the sunscreen composition of any one of Aspects 26 to 28, wherein the one or more solubilizers are decyl cocoate, isopropyl lauroyl sarcosinate, and dibutyl adipate.
  • Aspect 30 provides the sunscreen composition of Aspect 29, wherein the composition comprises from about 16% to about 18% of a mixture of decyl cocoate, isopropyl lauroyl sarcosinate, and dibutyl adipate.
  • Aspect 31 provides the sunscreen composition of Aspect 30, wherein the composition comprises from about 16.5% to about 17.5% of a mixture of decyl cocoate, isopropyl lauroyl sarcosinate, and dibutyl adipate.
  • Aspect 32 provides the sunscreen composition of Aspect 5, wherein the UV-A filter is Butyl methoxydibenzoylmethane, a first UV-B filter is Ethylhexyl triazone, a second UV-B filter is octyl salicylate, a third UV-B filter is Isoamyl p-methoxycinnamate, and the broad band UV-A and UV-B filter is bis-ethylhexyloxyphenol methoxyphenyl triazine, wherein the mass ratio of UV-A filter to UV-B filters to broad band filter is about 1 : 2 : 1.
  • Aspect 33 provides the sunscreen composition of Aspect 9, wherein the UV-A filter is Butyl methoxydibenzoylmethane, a first UV-B filter is Ethylhexyl triazone, a second UV-B filter is octyl salicylate, a third UV-B filter is diethylhexyl butamido triazone, and the broad band UV-A and UV-B filter is bis-ethylhexyloxyphenol methoxyphenyl triazine, wherein the mass ratio of UV-A filter to UV-B filters to broad band filter is about 3 : 8.5 : 2.
  • Aspect 34 provides the sunscreen composition of Aspect 13, wherein the UV-A filter is Butyl m ethoxy dibenzoylmethane, a first UV-B filter is Isoamyl p-methoxycinnamate, a second UV-B filter is octyl salicylate, a third UV-B filter is diethylhexyl butamido triazone, and the broad band UV-A and UV-B filter is bis-ethylhexyloxyphenol methoxyphenyl triazine, wherein the mass ratio of UV-A filter to UV-B filters to broad band filter is about 1 : 2 : 1.
  • Aspect 35 provides the sunscreen composition of any one of Aspects 32 to 34, wherein the one or more solubilizers are decyl cocoate and diisopropyl sebacate.
  • Aspect 36 provides the sunscreen composition of Aspect 35, wherein the composition comprises from about 19% to about 21% of a mixture of decyl cocoate and diisopropyl sebacate.
  • Aspect 37 provides the sunscreen composition of Aspect 36, wherein the composition comprises from about 19.5% to about 20.5% of a mixture of decyl cocoate and diisopropyl sebacate.
  • Aspect 38 provides the sunscreen composition of Aspect 5, wherein the UV-A filter is Butyl methoxy dibenzoylmethane, a first UV-B filter is Ethylhexyl triazone, a second UV-B filter is octyl salicylate, a third UV-B filter is Isoamyl p-methoxycinnamate, and the broad band UV-A and UV-B filter is bis-ethylhexyloxyphenol methoxyphenyl triazine, wherein the mass ratio of UV-A filter to UV-B filters to broad band filter is about 7 : 13 : 6.
  • Aspect 39 provides the sunscreen composition of Aspect 9, wherein the UV-A filter is Butyl methoxy dibenzoylmethane, a first UV-B filter is Ethylhexyl triazone, a second UV-B filter is octyl salicylate, a third UV-B filter is diethylhexyl butamido triazone, and the broad band UV-A and UV-B filter is bis-ethylhexyloxyphenol methoxyphenyl triazine, wherein the mass ratio of UV-A filter to UV-B filters to broad band filter is about 7 : 11 : 6.
  • Aspect 40 provides the sunscreen composition of Aspect 13, wherein the UV-A filter is Butyl methoxy dibenzoylmethane, a first UV-B filter is Isoamyl p-methoxycinnamate, a second UV-B filter is octyl salicylate, a third UV-B filter is diethylhexyl butamido triazone, and the broad band UV-A and UV-B filter is bis-ethylhexyloxyphenol methoxyphenyl triazine, wherein the mass ratio of UV-A filter to UV-B filters to broad band filter is about 7 : 11 : 6.
  • Aspect 41 provides the sunscreen composition of any one of Aspects 38 to 40, wherein the one or more solubilizers are diisopropyl sebacate, dicaprylyl carbonate, and decyl cocoate.
  • Aspect 42 provides the sunscreen composition of Aspect 41, wherein the composition comprises from about 19.5% to about 21.5% of a mixture of diisopropyl sebacate, dicaprylyl carbonate, and decyl cocoate.
  • Aspect 43 provides the sunscreen composition of Aspect 42, wherein the composition comprises from about 20% to about 21% of a mixture of diisopropyl sebacate, dicaprylyl carbonate, and decyl cocoate.
  • Aspect 44 provides the sunscreen composition of any one of Aspects 38 to 40, wherein the one or more solubilizers are diisopropyl sebacate, decyl cocoate, and isopropyl lauroyl sarcosinate.
  • Aspect 45 provides the sunscreen composition of Aspect 44, wherein the composition comprises from about 16% to about 18% of a mixture of diisopropyl sebacate, decyl cocoate, and isopropyl lauroyl sarcosinate.
  • Aspect 46 provides the sunscreen composition of Aspect 45, wherein the composition comprises from about 16.5% to about 17.5% of a mixture of diisopropyl sebacate, decyl cocoate, and isopropyl lauroyl sarcosinate.
  • Aspect 47 provides the sunscreen composition of Aspect 5, wherein the UV-A filter is Butyl methoxydibenzoylmethane, a first UV-B filter is Ethylhexyl triazone, a second UV-B filter is octyl salicylate, a third UV-B filter is Isoamyl p-methoxycinnamate, and the broad band UV-A and UV-B filter is bis-ethylhexyloxyphenol methoxyphenyl triazine, wherein the mass ratio of UV-A filter to UV-B filters to broad band filter is about 9 :
  • Aspect 48 provides the sunscreen composition of Aspect 9, wherein the UV-A filter is Butyl methoxydibenzoylmethane, a first UV-B filter is Ethylhexyl triazone, a second UV-B filter is octyl salicylate, a third UV-B filter is diethylhexyl butamido triazone, and the broad band UV-A and UV-B filter is bis-ethylhexyloxyphenol methoxyphenyl triazine, wherein the mass ratio of UV-A filter to UV-B filters to broad band filter is about 9 :
  • Aspect 49 provides the sunscreen composition of Aspect 13, wherein the UV-A filter is Butyl methoxydibenzoylmethane, a first UV-B filter is Isoamyl p-methoxycinnamate, a second UV-B filter is octyl salicylate, a third UV-B filter is diethylhexyl butamido triazone, and the broad band UV-A and UV-B filter is bis-ethylhexyloxyphenol methoxyphenyl triazine, wherein the mass ratio of UV-A filter to UV-B filters to broad band filter is about 9 : 24 : 8.
  • Aspect 50 provides the sunscreen composition of any one of Aspects 47 to 49, wherein the one or more solubilizers are diisopropyl sebacate, dicaprylyl carbonate, and decyl cocoate.
  • Aspect 51 provides the sunscreen composition of Aspect 5, wherein the composition comprises from about 25% to about 29% of a mixture of diisopropyl sebacate, dicaprylyl carbonate, and decyl cocoate.
  • Aspect 52 provides the sunscreen composition of Aspect 51, wherein the composition comprises from about 26% to about 28% of a mixture of diisopropyl sebacate, dicaprylyl carbonate, and decyl cocoate.
  • Aspect 53 provides the sunscreen composition of any one of Aspects 47 to 51, wherein the one or more solubilizers are diisopropyl sebacate and diisopropyl adipate.
  • Aspect 54 provides the sunscreen composition of Aspect 53, wherein the composition comprises from about 32.5% to about 35/5% of a mixture of diisopropyl sebacate and diisopropyl adipate.
  • Aspect 55 provides the sunscreen composition of Aspect 54, wherein the composition comprises from about 33% to about 35% of a mixture of diisopropyl sebacate and diisopropyl adipate.
  • Aspect 56 provides the sunscreen composition of any one of Aspects 47 to 49, wherein the one or more solubilizers are diisopropyl sebacate, decyl cocoate and isopropyl lauroyl sarcosinate.
  • Aspect 57 provides the sunscreen composition of Aspect 56, wherein the composition comprises from about 22.5% to about 25.5% of a mixture of diisopropyl sebacate, decyl cocoate and isopropyl lauroyl sarcosinate.
  • Aspect 58 provides the sunscreen composition of Aspect 57, wherein the composition comprises from about 23% to about 25% of a mixture of diisopropyl sebacate, decyl cocoate and isopropyl lauroyl sarcosinate.
  • Aspect 59 provides the sunscreen composition of any one of Aspects 47 to 49, wherein the one or more solubilizers are decyl cocoate, isopropyl lauroyl sarcosinate, and dibutyl adipate.
  • Aspect 60 provides the sunscreen composition of Aspect 59, wherein the composition comprises from about 28% to about 31% of a mixture of decyl cocoate, isopropyl lauroyl sarcosinate, and dibutyl adipate.
  • Aspect 61 provides the sunscreen composition of Aspect 60, wherein the composition comprises from about 29% to about 3-% of a mixture of decyl cocoate, isopropyl lauroyl sarcosinate, and dibutyl adipate.
  • Aspect 62 provides the sunscreen composition of Aspect 5, wherein the UV-A filter is Butyl methoxydibenzoylmethane, a first UV-B filter is Ethylhexyl triazone, a second UV-B filter is octyl salicylate, a third UV-B filter is Isoamyl p-methoxycinnamate, and the broad band UV-A and UV-B filter is bis-ethylhexyloxyphenol methoxyphenyl triazine, wherein the mass ratio of UV-A filter to UV-B filters to broad band filter is about 9 : 19 : 8.
  • Aspect 63 provides the sunscreen composition of Aspect 9, wherein the UV-A filter is Butyl methoxydibenzoylmethane, a first UV-B filter is Ethylhexyl triazone, a second UV-B filter is octyl salicylate, a third UV-B filter is diethylhexyl butamido triazone, and the broad band UV-A and UV-B filter is bis-ethylhexyloxyphenol methoxyphenyl triazine, wherein the mass ratio of UV-A filter to UV-B filters to broad band filter is about 9 :
  • Aspect 64 provides the sunscreen composition of Aspect 13, wherein the UV-A filter is Butyl methoxydibenzoylmethane, a first UV-B filter is Isoamyl p-methoxycinnamate, a second UV-B filter is octyl salicylate, a third UV-B filter is diethylhexyl butamido triazone, and the broad band UV-A and UV-B filter is bis-ethylhexyloxyphenol methoxyphenyl triazine, wherein the mass ratio of UV-A filter to UV-B filters to broad band filter is about 9 :
  • Aspect 65 provides the sunscreen composition of any one of Aspects 62 to 64, wherein the one or more solubilizers are diisopropyl sebacate, decyl cocoate, and isopropyl lauroyl sarcosinate.
  • Aspect 66 provides the sunscreen composition of Aspect 65, wherein the composition comprises from about 18% to about 22% of a mixture of diisopropyl sebacate, decyl cocoate, and isopropyl lauroyl sarcosinate.
  • Aspect 67 provides the sunscreen composition of Aspect 66, wherein the composition comprises from about 20% to about 21% of a mixture of diisopropyl sebacate, decyl cocoate, and isopropyl lauroyl sarcosinate.
  • Aspect 68 provides the sunscreen composition of any one of Aspects 62 to 64, wherein the one or more solubilizers are diisopropyl sebacate, diisopropyl adipate, and decyl cocoate.
  • Aspect 69 provides the sunscreen composition of Aspect 68, wherein the composition comprises from about 29% to about 33% of a mixture of diisopropyl sebacate, diisopropyl adipate, and decyl cocoate.
  • Aspect 70 provides the sunscreen composition of Aspect 69, wherein the composition comprises from about 30% to about 32% of a mixture of diisopropyl sebacate, diisopropyl adipate, and decyl cocoate.
  • Aspect 71 provides the sunscreen composition of Aspect 5, wherein the UV-A filter is Butyl methoxydibenzoylmethane, a first UV-B filter is Ethylhexyl triazone, a second UV-B filter is octyl salicylate, a third UV-B filter is Isoamyl p-methoxycinnamate, and the broad band UV-A and UV-B filter is bis-ethylhexyloxyphenol methoxyphenyl triazine, wherein the mass ratio of UV-A filter to UV-B filters to broad band filter is about 9 :
  • Aspect 72 provides the sunscreen composition of Aspect 9, wherein the UV-A filter is Butyl methoxydibenzoylmethane, a first UV-B filter is Ethylhexyl triazone, a second UV-B filter is octyl salicylate, a third UV-B filter is diethylhexyl butamido triazone, and the broad band UV-A and UV-B filter is bis-ethylhexyloxyphenol methoxyphenyl triazine, wherein the mass ratio of UV-A filter to UV-B filters to broad band filter is about 9 :
  • Aspect 73 provides the sunscreen composition of Aspect 13, wherein the UV-A filter is Butyl methoxydibenzoylmethane, a first UV-B filter is Isoamyl p-methoxycinnamate, a second UV-B filter is octyl salicylate, a third UV-B filter is diethylhexyl butamido triazone, and the broad band UV-A and UV-B filter is bis-ethylhexyloxyphenol methoxyphenyl triazine, wherein the mass ratio of UV-A filter to UV-B filters to broad band filter is about 9 : 17 : 8.
  • Aspect 74 provides the sunscreen composition of any one of Aspects 71 to 73, wherein the one or more solubilizers are diisopropyl sebacate, diisopropyl adipate, and decyl cocoate.
  • Aspect 75 provides the sunscreen composition of Aspect 74, wherein the composition comprises from about 25% to about 2827% of a mixture of diisopropyl sebacate, diisopropyl adipate, and decyl cocoate.
  • Aspect 76 provides the sunscreen composition of Aspect 75, wherein the composition comprises from about 26% to about 27% of a mixture of diisopropyl sebacate, diisopropyl adipate, and decyl cocoate.
  • Aspect 77 provides the sunscreen composition of Aspect 5, wherein the UV-A filter is Butyl methoxydibenzoylmethane, a first UV-B filter is Ethylhexyl triazone, a second UV-B filter is octyl salicylate, a third UV-B filter is Isoamyl p-methoxycinnamate, and the broad band UV-A and UV-B filter is bis-ethylhexyloxyphenol methoxyphenyl triazine, wherein the mass ratio of UV-A filter to UV-B filters to broad band filter is about 9 :
  • Aspect 78 provides the sunscreen composition of Aspect 9, wherein the UV-A filter is Butyl methoxydibenzoylmethane, a first UV-B filter is Ethylhexyl triazone, a second UV-B filter is octyl salicylate, a third UV-B filter is diethylhexyl butamido triazone, and the broad band UV-A and UV-B filter is bis-ethylhexyloxyphenol methoxyphenyl triazine, wherein the mass ratio of UV-A filter to UV-B filters to broad band filter is about 9 :
  • Aspect 79 provides the sunscreen composition of Aspect 13, wherein the UV-A filter is Butyl methoxydibenzoylmethane, a first UV-B filter is Isoamyl p-methoxycinnamate, a second UV-B filter is octyl salicylate, a third UV-B filter is diethylhexyl butamido triazone, and the broad band UV-A and UV-B filter is bis-ethylhexyloxyphenol methoxyphenyl triazine, wherein the mass ratio of UV-A filter to UV-B filters to broad band filter is about 9 : 25 : 7.
  • Aspect 80 provides the sunscreen composition of any one of Aspects 77 to 79, wherein the one or more solubilizers are diisopropyl sebacate and dicaprylyl carbonate.
  • Aspect 81 provides the sunscreen composition of Aspect 80, wherein the composition comprises from about 17% to about 20% of a mixture of diisopropyl sebacate and dicaprylyl carbonate.
  • Aspect 82 provides the sunscreen composition of Aspect 81, wherein the composition comprises from about 18% to about 19% of a mixture of diisopropyl sebacate and dicaprylyl carbonate.
  • Aspect 83 provides the sunscreen composition of Aspect 5, wherein the UV-A filter is Butyl methoxydibenzoylmethane, a first UV-B filter is Ethylhexyl triazone, a second UV-B filter is octyl salicylate, a third UV-B filter is Isoamyl p-methoxycinnamate, and the broad band UV-A and UV-B filter is bis-ethylhexyloxyphenol methoxyphenyl triazine, wherein the mass ratio of UV-A filter to UV-B filters to broad band filter is about 9 :
  • Aspect 84 provides the sunscreen composition of Aspect 9, wherein the UV-A filter is Butyl methoxydibenzoylmethane, a first UV-B filter is Ethylhexyl triazone, a second UV-B filter is octyl salicylate, a third UV-B filter is diethylhexyl butamido triazone, and the broad band UV-A and UV-B filter is bis-ethylhexyloxyphenol methoxyphenyl triazine, wherein the mass ratio of UV-A filter to UV-B filters to broad band filter is about 9 :
  • Aspect 85 provides the sunscreen composition of Aspect 13, wherein the UV-A filter is Butyl methoxydibenzoylmethane, a first UV-B filter is Isoamyl p-methoxycinnamate, a second UV-B filter is octyl salicylate, a third UV-B filter is diethylhexyl butamido triazone, and the broad band UV-A and UV-B filter is bis-ethylhexyloxyphenol methoxyphenyl triazine, wherein the mass ratio of UV-A filter to UV-B filters to broad band filter is about 9 :
  • Aspect 86 provides the sunscreen composition of any one of Aspects 83 to 85, wherein the one or more solubilizers are diisopropyl sebacate, dicaprylyl carbonate, and decyl cocoate.
  • Aspect 87 provides the sunscreen composition of Aspect 86, wherein the composition comprises from about 20% to about 23% of a mixture of diisopropyl sebacate, dicapiylyl carbonate, and decyl cocoate.
  • Aspect 88 provides the sunscreen composition of Aspect 87, wherein the composition comprises from about 21% to about 22% of a mixture of diisopropyl sebacate, dicaprylyl carbonate, and decyl cocoate.
  • Aspect 89 provides the sunscreen composition of Aspect 5, wherein the UV-A filter is Butyl m ethoxy dibenzoylmethane, a first UV-B filter is Ethylhexyl triazone, a second UV-B filter is octyl salicylate, a third UV-B filter is Isoamyl p-methoxycinnamate, and the broad band UV-A and UV-B filter is bis-ethylhexyloxyphenol methoxyphenyl triazine, wherein the mass ratio of UV-A filter to UV-B filters to broad band filter is about 9 : 18 : 8.
  • Aspect 90 provides the sunscreen composition of Aspect 9, wherein the UV-A filter is Butyl methoxydibenzoylmethane, a first UV-B filter is Ethylhexyl triazone, a second UV-B filter is octyl salicylate, a third UV-B filter is diethylhexyl butamido triazone, and the broad band UV-A and UV-B filter is bis-ethylhexyloxyphenol methoxyphenyl triazine, wherein the mass ratio of UV-A filter to UV-B filters to broad band filter is about 9 :
  • Aspect 91 provides the sunscreen composition of Aspect 13, wherein the UV-A filter is Butyl methoxydibenzoylmethane, a first UV-B filter is Isoamyl p-methoxycinnamate, a second UV-B filter is octyl salicylate, a third UV-B filter is diethylhexyl butamido triazone, and the broad band UV-A and UV-B filter is bis-ethylhexyloxyphenol methoxyphenyl triazine, wherein the mass ratio of UV-A filter to UV-B filters to broad band filter is about 9 :
  • Aspect 92 provides the sunscreen composition of any one of Aspects 89 to 91, wherein the one or more solubilizers are dibutyl adipate.
  • Aspect 93 provides the sunscreen composition of Aspect 92, wherein the composition comprises from about 36% to about 39% of dibutyl adipate.
  • Aspect 94 provides the sunscreen composition of Aspect 93, wherein the composition comprises from about 37% to about 38% dibutyl adipate.
  • Aspect 95 provides the sunscreen composition of Aspect 5, wherein the UV-A filter is Butyl methoxydibenzoylmethane, a first UV-B filter is Ethylhexyl triazone, a second UV-B filter is octyl salicylate, a third UV-B filter is Isoamyl p-methoxycinnamate, and the broad band UV-A and UV-B filter is bis-ethylhexyloxyphenol methoxyphenyl triazine, wherein the mass ratio of UV-A filter to UV-B filters to broad band filter is about 9 : 18 : 8.
  • Aspect 96 provides the sunscreen composition of Aspect 9, wherein the UV-A filter is Butyl methoxydibenzoylmethane, a first UV-B filter is Ethylhexyl triazone, a second UV-B filter is octyl salicylate, a third UV-B filter is diethylhexyl butamido triazone, and the broad band UV-A and UV-B filter is bis-ethylhexyloxyphenol methoxyphenyl triazine, wherein the mass ratio of UV-A filter to UV-B filters to broad band filter is about 9 : 20 : 7.
  • Aspect 97 provides the sunscreen composition of Aspect 13, wherein the UV-A filter is Butyl methoxydibenzoylmethane, a first UV-B filter is Isoamyl p-methoxycinnamate, a second UV-B filter is octyl salicylate, a third UV-B filter is diethylhexyl butamido triazone, and the broad band UV-A and UV-B filter is bis-ethylhexyloxyphenol methoxyphenyl triazine, wherein the mass ratio of UV-A filter to UV-B filters to broad band filter is about 9 : 18 : 8.
  • Aspect 98 provides the sunscreen composition of any one of Aspects 94 to 97, wherein the one or more solubilizers are diisopropyl sebacate, dicaprylyl carbonate, and decyl cocoate.
  • Aspect 99 provides the sunscreen composition of Aspect 98, wherein the composition comprises from about 23% to about 26% of a mixture of diisopropyl sebacate, dicaprylyl carbonate, and decyl cocoate.
  • Aspect 100 provides the sunscreen composition of Aspect 99, wherein the composition comprises from about 24% to about 25% of a mixture of diisopropyl sebacate, dicaprylyl carbonate, and decyl cocoate.
  • Aspect 101 provides the sunscreen composition of any one of Aspects 95 to 97, wherein the one or more solubilizers are diisopropyl sebacate, decyl cocoate, and diisopropyl adipate.
  • Aspect 102 provides the sunscreen composition of Aspect 101, wherein the composition comprises from about 25% to about 28% of a mixture of diisopropyl sebacate, decyl cocoate, and diisopropyl adipate.
  • Aspect 103 provides the sunscreen composition of Aspect 102, wherein the composition comprises from about 26% to about 27% of a mixture of diisopropyl sebacate, decyl cocoate, and diisopropyl adipate.
  • Aspect 104 provides the sunscreen composition of Aspect 5, wherein the UV-A filter is Butyl methoxy dibenzoylmethane, a first UV-B filter is Ethylhexyl triazone, a second UV-B filter is octyl salicylate, a third UV-B filter is Isoamyl p-methoxyci nnamate, and the broad band UV-A and UV-B filter is bis-ethylhexyloxyphenol methoxyphenyl triazine, wherein the mass ratio of UV-A filter to UV-B filters to broad band filter is about 9 :
  • Aspect 105 provides the sunscreen composition of Aspect 9, wherein the UV-A filter is Butyl m ethoxy dibenzoylmethane, a first UV-B filter is Ethylhexyl triazone, a second UV-B filter is octyl salicylate, a third UV-B filter is diethylhexyl butamido triazone, and the broad band UV-A and UV-B filter is bis-ethylhexyloxyphenol methoxyphenyl triazine, wherein the mass ratio of UV-A filter to UV-B filters to broad band filter is about 9 :
  • Aspect 106 provides the sunscreen composition of Aspect 13, wherein the UV-A filter is Butyl methoxydibenzoylmethane, a first UV-B filter is Isoamyl p-methoxycinnamate, a second UV-B filter is octyl salicylate, a third UV-B filter is diethylhexyl butamido triazone, and the broad band UV-A and UV-B filter is bis-ethylhexyloxyphenol methoxyphenyl triazine, wherein the mass ratio of UV-A filter to UV-B filters to broad band filter is about 9 :
  • Aspect 107 provides the sunscreen composition of any one of Aspects 104 to 106, wherein the one or more solubilizers are dicapiylyl carbonate.
  • Aspect 108 provides the sunscreen composition of Aspect 107, wherein the composition comprises from about 26% to about 27% of dicaprylyl carbonate.
  • Aspect 109 provides the sunscreen composition of Aspect 108, wherein the composition comprises from about 24% to about 26% of dicapiylyl carbonate.
  • Aspect 110 provides the sunscreen composition of Aspect 5, wherein the UV-A filter is Butyl methoxydibenzoylmethane, a first UV-B filter is Ethylhexyl triazone, a second UV-B filter is octyl salicylate, a third UV-B filter is Isoamyl p-methoxycinnamate, and the broad band UV-A and UV-B filter is bis-ethylhexyloxyphenol methoxyphenyl triazine, wherein the mass ratio of UV-A filter to UV-B filters to broad band filter is about 9 :
  • Aspect 111 provides the sunscreen composition of Aspect 9, wherein the UV-A filter is Butyl methoxydibenzoylmethane, a first UV-B filter is Ethylhexyl triazone, a second UV-B filter is octyl salicylate, a third UV-B filter is diethylhexyl butamido triazone, and the broad band UV-A and UV-B filter is bis-ethylhexyloxyphenol methoxyphenyl triazine, wherein the mass ratio of UV-A filter to UV-B filters to broad band filter is about 9 : 14 : 8.
  • Aspect 112 provides the sunscreen composition of Aspect 13, wherein the UV-A filter is Butyl methoxydibenzoylmethane, a first UV-B filter is Isoamyl p-methoxycinnamate, a second UV-B filter is octyl salicylate, a third UV-B filter is diethylhexyl butamido triazone, and the broad band UV-A and UV-B filter is bis-ethylhexyloxyphenol methoxyphenyl triazine, wherein the mass ratio of UV-A filter to UV-B filters to broad band filter is about 9 :
  • Aspect 113 provides the sunscreen composition of any one of Aspects 110 to 112, wherein the one or more solubilizers are diisopropyl sebacate, dicaprylyl carbonate, and decyl cocoate.
  • Aspect 114 provides the sunscreen composition of Aspect 113, wherein the composition comprises from about 24% to about 27% of a mixture of diisopropyl sebacate, dicaprylyl carbonate, and decyl cocoate.
  • Aspect 115 provides the sunscreen composition of Aspect 114, wherein the composition comprises from about 25% to about 26% of a mixture of diisopropyl sebacate, dicaprylyl carbonate, and decyl cocoate.
  • Aspect 116 provides the sunscreen composition of Aspect 5, wherein the UV-A filter is Butyl methoxydibenzoylmethane, a first UV-B filter is Ethylhexyl triazone, a second UV-B filter is octyl salicylate, a third UV-B filter is Isoamyl p-methoxycinnamate, and the broad band UV-A and UV-B filter is bis-ethylhexyloxyphenol methoxyphenyl triazine, wherein the mass ratio of UV-A filter to UV-B filters to broad band filter is about 9 :
  • Aspect 117 provides the sunscreen composition of Aspect 9, wherein the UV-A filter is Butyl methoxydibenzoylmethane, a first UV-B filter is Ethylhexyl triazone, a second UV-B filter is octyl salicylate, a third UV-B filter is diethylhexyl butamido triazone, and the broad band UV-A and UV-B filter is bis-ethylhexyloxyphenol methoxyphenyl triazine, wherein the mass ratio of UV-A filter to UV-B filters to broad band filter is about 9 :
  • Aspect 118 provides the sunscreen composition of Aspect 13, wherein the UV-A filter is Butyl methoxydibenzoylmethane, a first UV-B filter is Isoamyl p-methoxycinnamate, a second UV-B filter is octyl salicylate, a third UV-B filter is diethylhexyl butamido triazone, and the broad band UV-A and UV-B filter is bis-ethylhexyloxyphenol methoxyphenyl triazine, wherein the mass ratio of UV-A filter to UV-B filters to broad band filter is about 9 :
  • Aspect 119 provides the sunscreen composition of any one of Aspects 116 to 118, wherein the one or more solubilizers are dibutyl adipate, and decyl cocoate.
  • Aspect 120 provides the sunscreen composition of Aspect 119, wherein the composition comprises from about 31% to about 34% of a mixture of diisopropyl sebacate, dicaprylyl carbonate, and decyl cocoate.
  • Aspect 121 provides the sunscreen composition of Aspect 120, wherein the composition comprises from about 32% to about 33% of a mixture of diisopropyl sebacate, dicaprylyl carbonate, and decyl cocoate.
  • Aspect 122 provides a method for protecting skin from sun damage comprising applying a sunscreen composition of any one of Aspects 2 to 121 to the skin.
  • Example 3 [0354] The following formulations can be prepared using methods known in the art.
  • a face cream with an SPF of at least 50 is prepared as an emulsion.
  • An oil phase comprising a UV filter composition as described herein, one or more solubilizers as described herein, a thickener, an emulsier, and wax is prepared.
  • the oil phase is added to an aqueous phase which comprises water and glycerine, with mixing.
  • Rheology modifiers, pigments, preservatives, fragrances, and active ingredients can be added.
  • Example 6 Various sunscreens were formulated with varying concentrations of UV filters. Specifically, three sunsvrees each including at total of five UV filters were developed and compared to a sunscreen formulation that included nine UV filters. The formulaitons are presented below and list out the type and concentration of the UV filters.
  • Table 8 Formula 3 [0357] The sun protection factor (SPF), persistent pigment darkening (PPD), and quotient of SPF/PPD were compared between the Compartive Formula, Formula 1, Formula 2, and Formula 3. The results showed that Formula 1, Formula 2, and Formula 3 yieled equivalent or better performance than Comparative Formula. Notably, the equivalent or better performance was achieved by Formula 1, Formula 2, and Formula 3 having fewer total filters and a lower overall concentration of filters by wt%. Results are show in FIGs. 1-6.
  • SPPF sun protection factor
  • PPD persistent pigment darkening
  • FIG. 1 shows that the in vivo SPF of Formula 1 and Formula 2 are substantially the same as the SPF of Comparative Formula.
  • FIG. 2 shows that Formula 1 has substantialy the same PPD as Comparative Formula.
  • FIG. 3 shows that Formula 1 has substantially the same SPF/PPD quotient as Comparative Formula.
  • FIG. 4 shows that Formula 3 has an improved SPF relative to Comparative Formula.
  • FIG. 5 shows that Formula 3 has substantially the same PPD as Comparative Formula.
  • FIG. 6 shows that Formula 3 has substantially the same SPF/PPD quotient as Comparative Formula.

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PCT/US2020/061238 2019-11-20 2020-11-19 Sunscreen compositions with multiple photoprotecting uv filters WO2021102113A1 (en)

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CN202080080833.7A CN114746070A (zh) 2019-11-20 2020-11-19 具有多种光防护uv滤光剂的防晒霜组合物
EP20824816.1A EP4061319A1 (en) 2019-11-20 2020-11-19 Sunscreen compositions with multiple photoprotecting uv filters
BR112022009548A BR112022009548A2 (pt) 2019-11-20 2020-11-19 Composições de protetor solar com múltiplos filtros uv de fotoproteção

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Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2023049821A1 (en) * 2021-09-23 2023-03-30 Edgewell Personal Care Brands, Llc Sunscreen composition with crystalline organic sunscreen filters

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN117598932B (zh) * 2023-11-29 2024-05-10 追光生物科技有限公司 防晒增效组合物、油包水型高倍防晒组合物及其制备方法

Citations (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4122029A (en) 1977-07-27 1978-10-24 Dow Corning Corporation Emulsion compositions comprising a siloxane-oxyalkylene copolymer and an organic surfactant
US4781917A (en) 1987-06-26 1988-11-01 The Proctor & Gamble Company Antiperspirant gel stick
EP1213010A2 (de) * 2000-12-09 2002-06-12 Beiersdorf AG Verwendung von wasserlöslichen, filmbildenden Polymeren zur Verstärkung des Lichtschutzfaktors und/oder der UV-A-Schutzleistung kosmetischer oder dermatologischer Formulierungen
US6685952B1 (en) 1999-06-25 2004-02-03 Unilever Home & Personal Care Usa, Division Of Conopco, Inc. Personal care compositions and methods-high internal phase water-in-volatile silicone oil systems
US6820014B2 (en) 2001-12-20 2004-11-16 Coty B.V. Method for determination of realistic UV protection factors or broad spectrum indices
EP1579847A1 (de) * 2004-03-23 2005-09-28 Beiersdorf AG Kosmetische und dermatologische Lichtschutzformulierungen
EP1728501A1 (de) * 2005-05-30 2006-12-06 Beiersdorf AG Polypeptidgebundene UV-Lichtschutzfilter in kosmetischen Zubereitungen
WO2010127987A2 (en) * 2009-05-04 2010-11-11 Dsm Ip Assets B.V. Sunscreens
WO2015155158A1 (en) * 2014-04-11 2015-10-15 Basf Se Mixtures of cosmetic uv absorbers
WO2016012586A1 (en) * 2014-07-25 2016-01-28 Basf Se Sunscreen formulations optimized for the formation of vitamin d
WO2017124156A1 (en) * 2016-01-22 2017-07-27 Armstrong Ernest T Compositions that brighten skin, provide sun protection, and permit vitamin d production

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US9572759B2 (en) * 2015-06-25 2017-02-21 L'oreal Sunscreen compositions having synergistic combination of UV filters
DE102016211238A1 (de) * 2016-06-23 2017-12-28 Beiersdorf Ag Sonnenschutzmittel mit reduzierter Textilverfleckung

Patent Citations (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4122029A (en) 1977-07-27 1978-10-24 Dow Corning Corporation Emulsion compositions comprising a siloxane-oxyalkylene copolymer and an organic surfactant
US4781917A (en) 1987-06-26 1988-11-01 The Proctor & Gamble Company Antiperspirant gel stick
US6685952B1 (en) 1999-06-25 2004-02-03 Unilever Home & Personal Care Usa, Division Of Conopco, Inc. Personal care compositions and methods-high internal phase water-in-volatile silicone oil systems
EP1213010A2 (de) * 2000-12-09 2002-06-12 Beiersdorf AG Verwendung von wasserlöslichen, filmbildenden Polymeren zur Verstärkung des Lichtschutzfaktors und/oder der UV-A-Schutzleistung kosmetischer oder dermatologischer Formulierungen
US6820014B2 (en) 2001-12-20 2004-11-16 Coty B.V. Method for determination of realistic UV protection factors or broad spectrum indices
EP1579847A1 (de) * 2004-03-23 2005-09-28 Beiersdorf AG Kosmetische und dermatologische Lichtschutzformulierungen
EP1728501A1 (de) * 2005-05-30 2006-12-06 Beiersdorf AG Polypeptidgebundene UV-Lichtschutzfilter in kosmetischen Zubereitungen
WO2010127987A2 (en) * 2009-05-04 2010-11-11 Dsm Ip Assets B.V. Sunscreens
WO2015155158A1 (en) * 2014-04-11 2015-10-15 Basf Se Mixtures of cosmetic uv absorbers
WO2016012586A1 (en) * 2014-07-25 2016-01-28 Basf Se Sunscreen formulations optimized for the formation of vitamin d
WO2017124156A1 (en) * 2016-01-22 2017-07-27 Armstrong Ernest T Compositions that brighten skin, provide sun protection, and permit vitamin d production

Non-Patent Citations (6)

* Cited by examiner, † Cited by third party
Title
"CFTA Cosmetic Ingredient Dictionary", vol. 21, 2019, US FOOD AND DRUG ADMINISTRATION
"INCI Ingredient Dictionary and Handbook", 2006
DATABASE GNPD [online] MINTEL; 23 July 2018 (2018-07-23), ANONYMOUS: "Water Resistant Sun Spray SPF 30", XP055639387, retrieved from https://www.gnpd.com/sinatra/recordpage/5844761/ Database accession no. 5844761 *
DATABASE GNPD [online] MINTEL; 3 August 2018 (2018-08-03), ANONYMOUS: "Face Cream SPF 50+", XP055778286, retrieved from https://www.gnpd.com/sinatra/recordpage/5871993/ Database accession no. 5871993 *
PISSAVINI ET AL.: "New Method to Reproduce In Vitro Cosmetic Product Photostability Findings", COSMETICS & TOILETRIES, vol. 127, no. 3, 2012, pages 208 - 218
TODD ET AL.: "Volatile Silicone Fluids for Cosmetics", COSMETICS AND TOILETRIES, vol. 91, 1976, pages 27 - 32

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2023049821A1 (en) * 2021-09-23 2023-03-30 Edgewell Personal Care Brands, Llc Sunscreen composition with crystalline organic sunscreen filters

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