WO2020166477A1 - Composition herbicide et procédé de lutte contre les mauvaises herbes - Google Patents

Composition herbicide et procédé de lutte contre les mauvaises herbes Download PDF

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WO2020166477A1
WO2020166477A1 PCT/JP2020/004518 JP2020004518W WO2020166477A1 WO 2020166477 A1 WO2020166477 A1 WO 2020166477A1 JP 2020004518 W JP2020004518 W JP 2020004518W WO 2020166477 A1 WO2020166477 A1 WO 2020166477A1
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compound
corn
trademark
mon
salt
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PCT/JP2020/004518
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Japanese (ja)
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義伸 神
由直 定
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住友化学株式会社
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    • A—HUMAN NECESSITIES
    • A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
    • A01N37/00—Biocides, pest repellants or attractants, or plant growth regulators containing organic compounds containing a carbon atom having three bonds to hetero atoms with at the most two bonds to halogen, e.g. carboxylic acids
    • A01N37/36—Biocides, pest repellants or attractants, or plant growth regulators containing organic compounds containing a carbon atom having three bonds to hetero atoms with at the most two bonds to halogen, e.g. carboxylic acids containing at least one carboxylic group or a thio analogue, or a derivative thereof, and a singly bound oxygen or sulfur atom attached to the same carbon skeleton, this oxygen or sulfur atom not being a member of a carboxylic group or of a thio analogue, or of a derivative thereof, e.g. hydroxy-carboxylic acids
    • A01N37/38—Biocides, pest repellants or attractants, or plant growth regulators containing organic compounds containing a carbon atom having three bonds to hetero atoms with at the most two bonds to halogen, e.g. carboxylic acids containing at least one carboxylic group or a thio analogue, or a derivative thereof, and a singly bound oxygen or sulfur atom attached to the same carbon skeleton, this oxygen or sulfur atom not being a member of a carboxylic group or of a thio analogue, or of a derivative thereof, e.g. hydroxy-carboxylic acids having at least one oxygen or sulfur atom attached to an aromatic ring system
    • A01N37/40—Biocides, pest repellants or attractants, or plant growth regulators containing organic compounds containing a carbon atom having three bonds to hetero atoms with at the most two bonds to halogen, e.g. carboxylic acids containing at least one carboxylic group or a thio analogue, or a derivative thereof, and a singly bound oxygen or sulfur atom attached to the same carbon skeleton, this oxygen or sulfur atom not being a member of a carboxylic group or of a thio analogue, or of a derivative thereof, e.g. hydroxy-carboxylic acids having at least one oxygen or sulfur atom attached to an aromatic ring system having at least one carboxylic group or a thio analogue, or a derivative thereof, and one oxygen or sulfur atom attached to the same aromatic ring system
    • A—HUMAN NECESSITIES
    • A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
    • A01N37/00—Biocides, pest repellants or attractants, or plant growth regulators containing organic compounds containing a carbon atom having three bonds to hetero atoms with at the most two bonds to halogen, e.g. carboxylic acids
    • A01N37/44—Biocides, pest repellants or attractants, or plant growth regulators containing organic compounds containing a carbon atom having three bonds to hetero atoms with at the most two bonds to halogen, e.g. carboxylic acids containing at least one carboxylic group or a thio analogue, or a derivative thereof, and a nitrogen atom attached to the same carbon skeleton by a single or double bond, this nitrogen atom not being a member of a derivative or of a thio analogue of a carboxylic group, e.g. amino-carboxylic acids
    • A01N37/46—N-acyl derivatives
    • A—HUMAN NECESSITIES
    • A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
    • A01N43/00—Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds
    • A01N43/34—Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds having rings with one nitrogen atom as the only ring hetero atom
    • A01N43/36—Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds having rings with one nitrogen atom as the only ring hetero atom five-membered rings
    • A—HUMAN NECESSITIES
    • A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
    • A01N43/00—Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds
    • A01N43/48—Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds having rings with two nitrogen atoms as the only ring hetero atoms
    • A01N43/54—1,3-Diazines; Hydrogenated 1,3-diazines
    • A—HUMAN NECESSITIES
    • A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
    • A01N43/00—Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds
    • A01N43/48—Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds having rings with two nitrogen atoms as the only ring hetero atoms
    • A01N43/56—1,2-Diazoles; Hydrogenated 1,2-diazoles
    • A—HUMAN NECESSITIES
    • A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
    • A01N43/00—Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds
    • A01N43/64—Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds having rings with three nitrogen atoms as the only ring hetero atoms
    • A01N43/647—Triazoles; Hydrogenated triazoles
    • A01N43/653—1,2,4-Triazoles; Hydrogenated 1,2,4-triazoles
    • A—HUMAN NECESSITIES
    • A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
    • A01N43/00—Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds
    • A01N43/713—Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds having rings with four or more nitrogen atoms as the only ring hetero atoms
    • A—HUMAN NECESSITIES
    • A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
    • A01N47/00—Biocides, pest repellants or attractants, or plant growth regulators containing organic compounds containing a carbon atom not being member of a ring and having no bond to a carbon or hydrogen atom, e.g. derivatives of carbonic acid
    • A01N47/08—Biocides, pest repellants or attractants, or plant growth regulators containing organic compounds containing a carbon atom not being member of a ring and having no bond to a carbon or hydrogen atom, e.g. derivatives of carbonic acid the carbon atom having one or more single bonds to nitrogen atoms
    • A01N47/10—Carbamic acid derivatives, i.e. containing the group —O—CO—N<; Thio analogues thereof
    • A01N47/24—Carbamic acid derivatives, i.e. containing the group —O—CO—N<; Thio analogues thereof containing the groups, or; Thio analogues thereof
    • A—HUMAN NECESSITIES
    • A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
    • A01N51/00—Biocides, pest repellants or attractants, or plant growth regulators containing organic compounds having the sequences of atoms O—N—S, X—O—S, N—N—S, O—N—N or O-halogen, regardless of the number of bonds each atom has and with no atom of these sequences forming part of a heterocyclic ring
    • A—HUMAN NECESSITIES
    • A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
    • A01N57/00—Biocides, pest repellants or attractants, or plant growth regulators containing organic phosphorus compounds
    • A01N57/18—Biocides, pest repellants or attractants, or plant growth regulators containing organic phosphorus compounds having phosphorus-to-carbon bonds
    • A01N57/20—Biocides, pest repellants or attractants, or plant growth regulators containing organic phosphorus compounds having phosphorus-to-carbon bonds containing acyclic or cycloaliphatic radicals

Definitions

  • the present invention relates to a herbicide composition and a weed control method.
  • herbicides have been used for the purpose of controlling weeds, and many compounds are known as active ingredients of herbicides.
  • a uracil compound having herbicidal activity is known (see Patent Document 1).
  • An object of the present invention is to provide a herbicidal composition that exhibits an excellent control effect against weeds.
  • Ethyl [3-[2-chloro-4-fluoro-5-(1-methyl-6-trifluoromethyl-2,4-dioxo-1,2,3,4-tetrahydropyrimidin-3-yl)
  • a herbicidal composition comprising phenoxy]-2-pyridyloxy]acetate and one or more compounds selected from the compound group Y.
  • Ethyl [3-[2-chloro-4-fluoro-5-(1-methyl-6-trifluoromethyl-2,4-dioxo-1,2,3,4-tetrahydropyrimidin-3-yl)
  • a method for controlling weeds which comprises the step of simultaneously or sequentially applying phenoxy]-2-pyridyloxy]acetate and one or more compounds selected from the compound group Y to a place where a weed is occurring or a place where the weed is occurring.
  • the present invention enables effective control of weeds.
  • the herbicidal composition of the present invention (hereinafter referred to as the present composition) comprises ethyl [3-[2-chloro-4-fluoro-5-(1-methyl-6-trifluoromethyl-2,4-dioxo -1,2,3,4-tetrahydropyrimidin-3-yl)phenoxy]-2-pyridyloxy]acetate (hereinafter referred to as compound X), and one or more compounds selected from the compound group Y (hereinafter Compound Y).
  • Compound X is a compound represented by the following formula (1) and described in US Pat. No. 6,537,948, and can be produced by a known method.
  • compound Y1 2-chloro-N-(1-methyl-1H-tetrazol-5-yl)-3-(methylthio)-4-(trifluoromethyl)benzamide (hereinafter referred to as compound Y1) is represented by the following formula (2).
  • compound Y2 2-methyl-N-(5-methyl-1,3,4-oxadiazol-2-yl)-3-(methanesulfonyl)-4-(trifluoromethyl)benzamide
  • compound Y2 is It is a compound represented by the following formula (3) and described in WO2012/126932, and can be produced by a known method.
  • 4-(4-fluorophenyl)-6-[(2-hydroxy-6-oxo-1-cyclohexen-1-yl)carbonyl]-2-methyl-1,2,4-triazine-3,5(2H, 4H)-dione (hereinafter referred to as compound Y3) is a compound represented by the following formula (4) and described in WO 2012/002096, and can be produced by a known method.
  • the compound Y may be in the form of an agriculturally acceptable salt with an inorganic base or an organic base, but the present invention also includes the case of using the salt form of the compound Y.
  • salts include inorganic bases (eg, alkali metal (lithium, sodium, potassium, etc.) hydroxides, carbonates, hydrogencarbonates, acetates, hydrides, alkaline earth metals (magnesium, calcium, (E.g., barium, etc.) hydroxide, hydride, etc., ammonia), organic bases (eg, dimethylamine, triethylamine, piperazine, pyrrolidine, piperidine, 2-phenylethylamine, benzylamine, ethanolamine, diethanolamine, pyridine, collidine, etc.), Examples thereof include salts formed by mixing with a metal alkoxide (eg, sodium methoxide, potassium tert-butoxide, magnesium methoxide, etc.).
  • a metal alkoxide eg, sodium
  • At least three crystal polymorphs having different crystal structures are known for compound X (International Publication No. 2018/178039).
  • the compound X described in the present invention includes all of these crystal polymorphs and a mixture of any two or more thereof.
  • a mixture consisting of any two or more of any crystals selected from the crystalline polymorphs described in WO2018/178039 also includes a mixture in which they are contained in an arbitrary ratio.
  • the volume median diameter of crystal particles is usually 0.1 to 10 ⁇ m, preferably 0.2 to 5 ⁇ m, more preferably 1 to 4 ⁇ m, and further preferably 2 to 3 ⁇ m.
  • an aqueous liquid suspension agent having a volume median diameter of crystal particles of 2 to 3 ⁇ m is preferable.
  • the particle size distribution of crystals can be expressed based on an arbitrary percentage other than medium (50%), and the preferable range is expressed as "volume 40% diameter 2.5 ⁇ m to volume 60% diameter 2.5 ⁇ m", etc. You can also Further, since the crystal density of the compound X having the specified crystal structure is unique, it is substantially the same even if the volume median diameter is expressed by the weight median diameter, and it should be expressed by an arbitrary percentage. Can also
  • At least two crystalline polymorphs having different crystal structures are known for compound Y1 (International Publication No. 2017/005585).
  • the compound Y1 described in the present invention includes all of these crystalline polymorphs and a mixture of any two or more thereof.
  • At least two crystal polymorphs having different crystal structures are known for compound Y2 (International Publication No. 2017/080912).
  • the compound Y2 described in the present invention includes all of these crystal polymorphs and a mixture of any two or more thereof.
  • the composition of the present invention is usually a preparation prepared by mixing the compound X and the compound Y with a carrier such as a solid carrier or a liquid carrier and, if necessary, adding an auxiliary agent for formulation such as a surfactant. is there.
  • Preferred dosage forms of such preparations are aqueous liquid suspension preparations, oil-based suspension preparations, wettable powders, wettable granules, granules, aqueous emulsions, oil-based emulsions, and emulsions, and more preferably emulsions.
  • the total content of the compound X and the compound Y in the composition of the present invention is usually 0.01 to 99% by weight, preferably 1 to 80% by weight.
  • the weight ratio of the compound X to the compound Y in the composition of the present invention is 1:0.1 to 1:100, preferably 1:0.12 to 1:80, more preferably 1:0.15 to 1:70, The range is more preferably 1:0.2 to 1:50, more preferably 1:0.3 to 1:30, and further preferably 1:0.5 to 1:20.
  • weight ratio of compound X and compound Y in the composition of the present invention are 1:0.5, 1:0.6, 1:0.7, 1:0.8, 1:0.9, 1:1, 1:1.2, 1:1.5, 1:1.7, 1:2, 1:2.5, 1:3, 1:4, 1:5, 1:7, 1: 10, 1:15, and 1:20.
  • the active ingredient of compound Y or other herbicide is a salt (eg glyphosate potassium salt, 2,4-D choline salt or dicamba BAPMA salt)
  • the weight is the acid equivalent unless otherwise specified. means.
  • composition of the present invention exerts a synergistic herbicidal effect on a wide range of weeds than is expected from the herbicidal effect when each of the compound X and the compound Y is used alone, and ordinary tillage cultivation, It is possible to effectively control a wide range of weeds in crop fields, vegetable fields, orchards and non-agricultural fields where no-till cultivation is carried out, and to prevent harmful phytotoxicity against useful plants.
  • the composition of the present invention may be used in combination with other pesticidal active compounds.
  • insecticide compound, nematicide compound and fungicide compound used in combination with the composition of the present invention include neonicotinoid compounds, diamide compounds, carbamate compounds, organophosphorus compounds and biological nematicides.
  • the method of controlling weeds of the present invention is to apply compound X and compound Y to a place where weeds are generated or a place where weeds are generated in a crop field, a vegetable field, an orchard or a non-arable land. There is a step of doing. In crop fields and vegetable fields, compound X and compound Y may be applied before sowing, at the same time as sowing, and/or after sowing.
  • the method of the present invention has a step of simultaneously applying or sequentially applying the compound X and the compound Y to a place where weeds are occurring or a place where weeds are occurring.
  • the order of applying compound X and compound Y is not particularly limited.
  • the weight ratio of compound X to compound Y is 1:0.1 to 1:100, preferably 1:0.12 to 1:80, more preferably 1:0.15 to 1:70, and The range is preferably 1:0.2 to 1:50, more preferably 1:0.3 to 1:30, and further preferably 1:0.5 to 1:20.
  • weight ratio of compound X and compound Y in the method of the present invention are 1:0.5, 1:0:6, 1:0.7, 1:0.8, 1:0.9, 1 : 1, 1:1.2, 1:1.5, 1:1.7, 1:2, 1:2.5, 1:3, 1:4, 1:5, 1:7, 1:10 , 1:15, and 1:20.
  • X and compound Y may be treated in a field in which the seeds of the crop have been sown or in a field to be sown.
  • the agricultural crop field in the present invention includes a peanut field, a soybean (infinite growth type, a finite growth type, a semi-finite growth type) field, a corn (a horse species, a hard grain species, a soft grain species, an explosive species, a waxy variety).
  • a field for cultivating solanaceous vegetables eggplant, tomato, peppers, capsicum, potatoes, etc.
  • a field for cultivating cucurbitaceae cucumber, pumpkin, zucchini, watermelon, melons, etc.
  • cruciferae Fields for cultivating vegetables radish, turnip, horseradish, kohlrabi, Chinese cabbage, cabbage, mustard, broccoli, cauliflower, etc.
  • fields for growing asteraceae vegetables burdock, shungiku, artichoke, lettuce, etc.
  • lily family vegetables leeks) , Fields for cultivating onions, garlic, asparagus), Fields for cultivating aeriaceous vegetables (carrots, parsley, celery, American bow-fowl, etc.), Fields for cultivating red-spotted vegetables (spinach, chard, etc.), Lamiaceae vegetables ( Fields for cultivating perilla, mint, basil, lavender), strawberry fields, sweet potato fields, yam fields, taro fields and the
  • the orchard in the present invention includes an orchard, a tea garden, a mulberry garden, a coffee garden, a banana garden, a palm garden, a flower garden, a flower garden, a nursery, a nursery, a forest garden, and a garden.
  • Fruit trees in the present invention include pome fruit (apple, pear, Japanese pear, carin, quince, etc.), drupe (peach, plum, nectarine, plum, sweet cherry, apricot, prunes, etc.), citrus (Unshukan, orange, Lemon, lime, grapefruit, etc.), nuts (chestnut, walnut, hazel, almond, pistachio, cashew nut, macadamia nut, etc.), berries (grape, blueberry, cranberry, blackberry, raspberry, etc.), oyster, olive, loquat. Etc. can be mentioned.
  • the non-agricultural land in the present invention may include a playground, a vacant lot, a track end, a park, a parking lot, a road end, a riverbed, a power transmission line, a residential land, a factory site, and the like.
  • the crops cultivated in the crop field in the present invention are not particularly limited as long as they are generally cultivated varieties.
  • the above-mentioned varieties of plants may be plants that can be produced by natural crossing, plants that can be generated by mutation, F1 hybrid plants, and transgenic plants (also referred to as genetically modified plants). These plants generally have tolerance to herbicides, accumulation of toxic substances against pests (also called pest resistance), suppression of susceptibility to diseases (also called disease resistance), increased yield potential, biological and abiotic organisms. It has properties such as improved resistance to stress factors, quality modification of products (for example, increase/decrease in content of specific components, change in composition, improvement in storability or processability).
  • the F1 hybrid plant is a first-generation hybrid obtained by crossing two varieties of different strains, and is generally a plant with hybrid vigor characteristics that is superior to both parents.
  • a transgenic plant has characteristics that cannot be easily obtained by cross breeding in the natural environment, mutagenesis or natural recombination by introducing a foreign gene from another organism such as a microorganism. It is an endowed plant.
  • Examples of techniques for producing the above-mentioned plants include conventional breeding techniques; gene recombination techniques; genome breeding techniques; new breeding techniques; genome editing techniques.
  • the conventional breeding technique is a technique for obtaining a plant having desirable properties by mutation or crossing.
  • the gene recombination technology is a technology for giving a new property to a target organism (for example, a microorganism) by extracting a target gene (DNA) from the organism and introducing it into the genome of another target organism, or a plant.
  • Antisense or RNA interference techniques that impart new or improved properties by silencing other genes that are present.
  • the genome breeding technique is a technique for improving breeding efficiency using genomic information, and includes a DNA marker (also called a genomic marker or a gene marker) breeding technique and genomic selection.
  • DNA marker breeding is a method of selecting a progeny having a target useful trait gene from a large number of mating progeny by using a DNA marker that is a DNA sequence that marks the location of a specific useful trait gene on the genome. is there.
  • a DNA marker that is a DNA sequence that marks the location of a specific useful trait gene on the genome.
  • Genomic selection is a method that creates prediction formulas from phenotypes and genomic information obtained in advance, and predicts characteristics without evaluating phenotypes from the prediction formulas and genomic information, contributing to efficient breeding. This is a possible technology.
  • New breeding techniques are a general term for breeding (breeding) techniques that combine molecular biological techniques.
  • the genome editing technique is a technique for converting genetic information in a sequence-specific manner, and it is possible to delete a base sequence, replace an amino acid sequence, introduce a foreign gene, or the like.
  • examples of such tools include zinc finger nucleases (Zinc-Finger, ZFN) capable of sequence-specific DNA cleavage, TALEN, Crisper Cassine (CRISPR/Cas9), CRISPER/Cpf1 And Meganuclease.
  • sequence-specific genome modification techniques such as CAS9 nickase and Target-AID created by modifying the above tools.
  • Examples of the above-mentioned plants include, for example, genetically modified crops on the electronic information site (http://www.isaaa.org/) of the International Agri-Bio Agency (INTERNATINAL SERVICE for for the the ACQUISITION of AGRI-BIOTECH APPLICATIONS, ISAAA).
  • the plants listed in the registration database are listed. More specifically, for example, herbicide-tolerant plants, pest-resistant plants, disease-resistant plants, quality modification of products (for example, increase or decrease in the content of specific components, change in composition, improvement in storability or processability). ) Plants, fertility trait-modified plants, abiotic stress-tolerant plants, or plants with altered traits related to growth or yield.
  • Examples of plants to which the herbicide resistance has been imparted are given below.
  • Mechanisms of tolerance to herbicides for example, reduce the affinity of the herbicide with its target; rapid metabolism (degradation, modification, etc.) of the herbicide by expression of an enzyme that inactivates the herbicide; Inhibition of uptake into plants; and inhibition of transfer of herbicides in plants.
  • Examples of plants to which the herbicide resistance has been imparted by gene recombination technology include protoporphyrinogen oxidase (hereinafter abbreviated as PPO) herbicides such as flumioxazin; 4-hydroxyphenylpyrubin such as isoxaflutol and mesotrione. Acid dioxygenase (hereinafter abbreviated as HPPD) inhibitors; Imidazolinone herbicides such as imazethapyr, Acetolactate synthase (hereinafter abbreviated as ALS) inhibitors such as sulfonylurea herbicides such as tifensulfuron-methyl; Glyphosate etc.
  • PPO protoporphyrinogen oxidase
  • HPPD Acid dioxygenase
  • Imidazolinone herbicides such as imazethapyr
  • EPSPS 5-enolpyruvylshikimate-3-phosphate synthase
  • glutamine synthase inhibitors such as glufosinate
  • auxinic herbicides such as 2,4-D and dicamba
  • Preferred herbicide-tolerant transgenic plants are cereals such as wheat, barley, rye and oats, canola, sorghum, soybean, corn, cotton, rice, rapeseed, sugar beet, sugar cane, grape, lentil, sunflower, alfalfa, pome fruit.
  • Vegetables such as drupe, coffee, tea, strawberry, grass, tomato, potato, cucumber, lettuce, more preferably grains such as wheat, barley, rye, oats, soybean, corn, cotton, rice, grape, Tomatoes, potatoes and pome fruits.
  • the specific herbicide-tolerant plants are shown below.
  • Glyphosate herbicide-tolerant plants glyphosate-resistant EPSPS gene (CP4 epsps) derived from Agrobacterium tumefaciens strain CP4 strain, and glyphosate N-acetyltransferase gene derived from Bacillus licheniformis.
  • N-acetyltransferase gene (gat4601 or gat4621), glyphosate oxidase gene (goxv247) derived from Ochrobacterum anthropi strain LBAA, or EPSPS gene having glyphosate resistance mutation derived from corn (Zea mays) ( mepsps or 2mepsps).
  • the main plants are, for example, alfalfa (Medicago sativa), Argentine canola (Brassica napus), cotton (Gossypium hirsutum L.), creeping bentgrass (Agrostis stolonifera), corn (Zea mays L.) polish canola (Brassica rapa), Examples include potato (Solanum tuberosum L.), soybean (Glycine max L.), sugar beet (Beta vulgaris) and wheat (Triticum aestivum). Several glyphosate tolerant plants are commercially available.
  • a genetically modified plant into which CP4 epsps has been introduced has a trade name including "Roundup Ready (registered trademark)", and a genetically modified plant into which gat4601 or gat4621 has been introduced is "Optimum GAT (trademark)” or "Optimum (registered trademark)”.
  • Gly canola or other trade name
  • transgenic plants into which mepsps or 2mepsps are introduced are sold under the trade name of "GlyTol (trademark)”.
  • corn is “Roundup Ready (trademark) Maize”, “Roundup Ready (trademark) 2 Maize”, “Agrisure (trademark) GT”, “Agrisure (trademark) GT/CB/”.
  • Glufosinate herbicide-tolerant plant a gene (bar) of phosphinothricin N-acetyltransferase (PAT) derived from Streptomyces hygroscopicus (bar), Streptomyces viridochrod. At least one of the PAT gene (pat syn) derived from Mogenes (Streptomyces viridochromogenes) or the PAT gene (pat syn) synthesized from Streptomyces viridochromogenes strain Tu494 (Streptomyces viridochromogenes strain Tu494) It is obtained by introducing.
  • PAT phosphinothricin N-acetyltransferase
  • main plants include Argentine canola (Brassica napus), chicory (Cichorium intybus) cotton (Gossypium hirsutum L.), corn (Zea mays L.) polish canola (Brassica rapa), rice (Oryza sativa L.), soybean. (Glycine max L.) and sugar beet (Beta vulgaris).
  • Argentine canola Brainssica napus
  • chicory Ceichorium intybus cotton
  • corn Zea mays L.
  • polish canola Brassica rapa
  • rice Oryza sativa L.
  • soybean. Glycine max L.
  • sugar beet Beta vulgaris
  • Some glufosinate-tolerant plants are commercially available.
  • transgenic plants into which bar or pat has been introduced are sold under the trade names of "LibertyLink (trademark)", "InVigor (trademark)", or "WideStrike (
  • corn is "Roundup Ready (trademark) 2,""Liberty Link (trademark),”"Herculex (trademark) I,””HerculexRW,””Herculex XTRA (trademark).
  • Ozaenae examples of main plants include Argentine canola (Brassica napus), cotton (Gossypium hirsutum L.), and tobacco (Nicotiana tabacum L.).
  • Argentine canola Brassica napus
  • cotton Gossypium hirsutum L.
  • tobacco Nicotiana tabacum L.
  • oxynyl herbicide tolerant plants are commercially available. For example, it is sold under the trade name of "Navigator (trademark)" or "BXN (trademark)”.
  • As a more specific oxynil herbicide-tolerant plant for example, cotton is sold under the trade name of "BXN (trademark) Cotton” and Argentine canola under the trade name of "Navigator (trademark) Cotton".
  • ALS herbicide-tolerant plants Carnation (Dianthus caryophyllus) into which the ALS herbicide-tolerant ALS gene (surB) derived from tobacco (Nicotiana tabacum) as a selection marker has been introduced is, for example, “Moondust (trademark)” or “Moonshadow (trademark)”. , “Moonshade(TM)”, “Moonlite(TM)”, “Moonaqua(TM)”, “Moonvista(TM)”, “Moonique(TM)”, “Moonpearl(TM)”, “Moonberry(TM)”. Or it is sold under the brand name of "Moonvelvet (trademark)”.
  • Flax (Linum usitatissumum L.) into which the ALS gene (als) for ALS herbicide resistance derived from Arabidopsis thaliana is introduced, for example, is sold under the trade name of “CDC Triffid Flax”.
  • Corn derived ALS herbicide resistant ALS gene (zm-hra) introduced corn having resistance to sulfonylurea and imidazolinone herbicides (Zea mays L.) is, for example, a trademark of "Optimum GAT (trademark)" Sold under the name.
  • Soybean having resistance to an imidazolinone herbicide into which an ALS herbicide-resistant ALS gene (csr1-2) derived from Arabidopsis thaliana has been introduced is sold, for example, under the trade name of “Cultivance”.
  • Soybeans in which an ALS herbicide-resistant ALS gene (gm-hra) derived from soybean (Glycine max) is introduced are, for example, trademarks of "Treus (trademark)", “Plenish (trademark)” and "Optimum GAT (trademark)”. Sold under the name.
  • an ALS herbicide-resistant ALS gene (S4-HrA) derived from tobacco Nicotiana tabacum cv.
  • HPPD herbicide tolerant plant Obtained by introducing the HPPD gene (avhppd-03) derived from oat (Avena sativa).
  • HPPD gene derived from oat (Avena sativa).
  • soybeans introduced with PAT gene (pat) derived from Streptomyces viridochromogenes (Streptomyes viridochromogenes), as a soybean having resistance to mesotrione and glufosinate, "Herbicide-tolerant Soybean line” Sold under the trade name.
  • 2,4-D-tolerant plants or ACCase herbicide-tolerant plants ACCase in which an aryloxyalkanoate dioxygenase gene (aad-1) derived from Sphingobium herbicidovorans is introduced
  • Herbicide tolerant corn is sold, for example, under the trade name "EnlistTM Maize”.
  • Soybeans and cottons having resistance to 2,4-D into which an allyloxyalkanoate diochigenase gene (aad-12) derived from Delftia acidovorans has been introduced are known.
  • “Enlist (trademark ) It is sold under the trade name of "Soybean”.
  • Dicamba herbicide tolerant plant Obtained by introducing a dicamba monooxygenase gene (dmo) derived from Stenotrophomonas maltophilia strain DI-6. Soybean and cotton into which the above genes have been introduced are known. Soybean (Glycine max L.) into which the glyphosate-resistant EPSPS gene (CP4 epsps) derived from the Agrobacterium tumefaciens strain CP4 strain (Agrobacterium tumefaciens strain CP4) was introduced at the same time as the above gene, for example, "Genuity (registered trademark) Roundup" It is sold under the trademark "Ready(TM) 2 Xtend(TM)".
  • dmo dicamba monooxygenase gene
  • DI-6 Stenotrophomonas maltophilia strain DI-6.
  • Soybean and cotton into which the above genes have been introduced are known. Soybean (Glycine max
  • Corn, sorghum and sugar cane see for example WO2008/051633, US7105724 and US5670454; soybean, sugar beet, potato, tomato and tobacco resistant to glufosinate (see for example US6376754, US5646024, US5561236); 2,4 -D resistant cotton, peppers, apples, tomatoes, sunflowers, tobacco, potatoes, corn, cucumber, wheat, soybeans, sorghum and cereals (for example, US6153401, US6100446, WO2005/107437, US5608147 and US5670454.
  • ALS-inhibiting herbicides for example, sulfonylurea herbicides or imidazolinone herbicides
  • Oats, nata, potatoes, rice, rye, sorghum, soybeans, sugar beet, sunflower, tobacco, tomato and wheat see, for example, US5013659, WO2006/060634, US4761373, US5304732, US6211438, US6211439 and US6222100, especially imidazolinones.
  • Rice that is resistant to herbicides rice that has a specific mutation (eg, S653N, S654K, A122T, S653(At)N, S654(At)K, A122(At)T) in the acetolactate synthesis gene (acetohydroxyacid synthase gene) (See, for example, US2003/0217381, WO2005/020673); HPPD inhibitor herbicides (for example, isoxazole herbicides such as isoxaflutol; triketone herbicides such as sulcotrione and mesotrione; And pyrazole series herbicides such as pyrazolinate) or barley, sugar cane, rice, corn, tobacco, soybean, cotton, rapeseed, sugar beet, wheat and potato (eg, WO2004) having resistance to diketonitrile which is a decomposition product of isoxaflutol.
  • HPPD inhibitor herbicides for example, isoxazole herbicides such as
  • RTDS Registered trademark
  • GRON Gene Repair Oligonucleotide
  • Another example is maize with reduced herbicide resistance and phytic acid content by deleting the endogenous gene IPK1 using zinc finger nuclease (see Nature 459, 437-441, 2009); Crisper
  • One example is rice that has been given herbicide tolerance using Cassine (see Rice, 7, 5, 2014).
  • soybean An example of a plant to which herbicide resistance has been imparted by the new breeding technology is soybean, in which the properties possessed by GM rootstock have been imparted to the scion by using a breeding technology that utilizes grafting.
  • a breeding technology that utilizes grafting.
  • glyphosate-tolerant Roundup Ready registered trademark
  • soybean in which non-transgenic soybean spikes are given glyphosate tolerance (see Weed Technology 2013, 27, 412. ).
  • Examples of plants to which resistance to lepidopteran pests has been imparted by gene recombination technology include, for example, delta-endotoxin ( ⁇ -endotoxin), which is an insecticidal protein derived from the soil bacterium Bacillus thuringiensis (hereinafter abbreviated as Bt bacterium).
  • ⁇ -endotoxin an insecticidal protein derived from the soil bacterium Bacillus thuringiensis
  • Maize Zea mays L.
  • soybean Glycine max L.
  • cotton Gossypium hirsutum L.
  • rice Oryza sativa L.
  • poplar Populus sp.
  • tomato Lopersicon esculentum
  • delta-endotoxins that impart resistance to lepidopteran pests include, for example, Cry1A, Cry1Ab, modified Cry1Ab (Cry1Ab with partial deletion), Cry1Ac, Cry1Ab-Ac (hybrid protein in which Cry1Ab and Cry1Ac are fused), Cry1C, Cry1F, Cry1Fa2 (modified cry1F), moCry1F (modified Cry1F), Cry1A.
  • hybrid protein in which Cry1Ab, Cry1Ac, Cry1F are fused examples include corn and potato into which a gene encoding a delta-endotoxin, which is an insecticidal protein derived from a soil bacterium Bt bacterium, is introduced. ..
  • Examples of the delta-endotoxin that imparts resistance to Coleoptera pests include Cry3A, mCry3A (modified Cry3A), Cry3Bb1, Cry34Ab1, Cry35Ab1, Cry6A, Cry6Aa, and mCry6Aa (modified Cry6Aa).
  • a plant imparted with resistance to Diptera pests by gene recombination technology for example, corn introduced with a synthetic gene encoding a hybrid protein eCry3.1Ab in which Cry3A and Cry1Ab derived from a Bt bacterium which is a soil bacterium are fused.
  • the insecticidal protein that imparts pest resistance to plants also includes hybrid proteins of the above insecticidal proteins, partially deleted proteins, and modified proteins.
  • Hybrid proteins have been made using recombinant techniques by combining different domains of multiple insecticidal proteins, such as Cry1Ab-Ac and Cry1A.
  • Cry1Ab-Ac As a partially deleted protein, Cry1Ab having a partially deleted amino acid sequence is known.
  • the modified protein is a protein in which one or more amino acids of natural delta-endotoxin are substituted, and Cry1Fa2, moCry1F, mCry3A and the like are known.
  • the modified protein includes a case where a proteolytic enzyme recognition sequence that does not exist in nature is inserted into a toxin, for example, a cathepsin G-recognition sequence is inserted into a Cry3A toxin Cry3A055 (see WO2003/018810. See).
  • a cotton (event MON88702) into which a modified BT protein Cry51Aa2 (Cry51Aa2.834_16) has been introduced by genetic recombination technology has been developed by Monsanto. Shows resistance to thrips such as genus species.
  • Vip3 (Vip3Aa to Vip3Aj, Vip3Ba, Vip3B and Vip3Ca are known as subclasses, and specifically Vip3Aa20 and Vip3Aa61 are known) and Vip4; Photorhabdus luminescens and the like.
  • potato expressing insecticidal protein Cry3A derived from Bt bacteria ⁇ Atlantic NewLeaf (trademark) potato'', ⁇ NewLeaf (trademark) Russet Burbank potato'', ⁇ Lugovskoi plus'', "Elizaveta plus”, "Hi-Lite NewLeaf (trademark) Y potato, Superior NewLeaf (trademark) potato” and “Shepody NewLeaf (trademark) Y potato”; rice “hanyou” expressing the insecticidal proteins Cry1Ab and Cry1Ac derived from Bt bacteria.
  • corn having resistance to corn rootworms “Yield Gard corn rootworm”, “YieldGard VT”, “Herculex RW”, “Herculex Rootworm” and “Agrisure CRW”; corn having resistance to corn borer “Yield Gard corn borer” , “YieldGard plus”, “YieldGard VT Pro”, “Agrisure CB/LL”, “Agrisure 3000GT”, “Hercules I”, “Hercules II”, “KnockOut”, “NatureGard” and “StarLink”; Western Beancut Worm , Corn borer, black cut worm and fall army worm resistant corn "Herculex I”, “Herculex Xtra”, “New Leaf”, “New Leaf Y” and “New Leaf Plus”; resistance to corn borer and corn rootworm “Yield Gard Plus” having resistance to cotton bolls "Bollgard I” and “Bollgard II” having resistance to false bollworm; Bollgard moth, cotton ball worm, fall army
  • Further plants having pest resistance are generally known, for example, Sankamaiga resistant rice (see, for example, Molecular Breeding, Volume 18 (2006), No. 1), Lepidoptera resistant lettuce (for example, US5349124), rice having resistance to Lepidoptera (for example, Nikameiga, Ichimonjiseri, rice Yoto, Kobunomeiga, rice case worm, and rice army worm) (see, for example, WO2001/021821).
  • Methods for producing such plants are generally known to the person skilled in the art and are described, for example, in the publications mentioned above.
  • lepidopteran pests for example, cut worms such as corn borers, corn earworms, black cut worms, and fall army worms
  • coleopteran pests corn rootworms
  • the aphid resistance gene “Rag1 (Resistance to Aphis glycines1)” gene or “Rag2 (Resistance to Aphis glycines) 2)” Soybean that has resistance to soybean aphid (Aphis glycines) (see J.Econ. Entomol., 2015, 108, 326.); Soybean that exhibits resistance to soybean cyst nematode (Heterodera glycines) (Phytopathology) , 2016, 106, 1444. ); Cotton showing resistance to Meloidogyne incognita (J. Nematol., 2009, 41, 140); Rice showing resistance to brown planthopper “Kanto BPH1”; and Hasmonyoto Soybean "Fukuminori” which shows resistance is mentioned.
  • Pest-resistant plants are preferably wheat (e.g. wheat, barley, rye, oats), corn, canola, sorghum, soybean, rice, rapeseed, sugar beet, sugar cane, grape, lentil, sunflower, alfalfa, Pome fruits, drupes, peanuts, coffee, tea, strawberries, turf, vegetables (e.g. tomato, potato, cucurbitaceae and lettuce) are selected, more preferably soybeans, tomatoes and more preferably soybeans.
  • Corn, tomatoes, rice and wheat eg wheat, barley, rye and oats
  • most preferably soybean, rice, corn and wheat eg wheat, barley, rye and oats).
  • Plants imparted with disease resistance by gene recombination technology express, for example, a so-called “pathogenicity-related protein” (PRP, for example, EP0392225) or a so-called “antifungal protein” (AFP, for example, US6864068). It is a plant that does.
  • pathogenicity-related protein PRP, for example, EP0392225
  • antifungal protein AFP, for example, US6864068
  • Various antifungal proteins having activity against phytopathogenic fungi have been isolated from specific plant species and are common knowledge. Examples of such anti-pathogenic substances and plants capable of synthesizing such anti-pathogenic substances are known, for example, from EP0392225, WO1993/05153, WO1995/33818, and EP0353191.
  • Plants having resistance to fungicidal pathogens, viral pathogens and bacterial pathogens are produced by introducing a pathogen resistance gene.
  • a number of resistance genes have been identified and isolated and used to improve pathogenic resistance, such resistance genes, for example, making tobacco mosaic virus (TMV) resistant tobacco plants.
  • NV gene introduced into tobacco lines sensitive to TMV (see, for example, US 5571706)
  • Prf gene introduced into plants to obtain enhanced pathogenic resistance
  • Rps2 gene from Arabidopsis thaliana see, for example, WO1995/028423, which was used to create resistance to bacterial pathogens such as Pseudomonas syringae.
  • Plants exhibiting a systemically acquired resistance response were obtained by introducing a nucleic acid molecule encoding the TIR domain of the N gene (see eg US 6630618).
  • Further examples of known resistance genes Xa21 gene that has been introduced into a large number of rice varieties (see, for example, US5952485, US5977434, WO1999/009151, WO1996/022375), for the genus colletotrichum (colletotrichum) for resistance Rcg1 gene (see, for example, US2006/225152), prp1 gene (see, for example, US5859332, WO2008/017706), ppv-cp gene for introducing resistance to plumpox virus (see, for example, US PP15,154Ps), P1 gene (see, for example, US5968828), genes such as Blb1, Blb2, Blb3, RB2 and Rpi-vnt1 for introducing resistance to potato phytophthora infestans in potato
  • Beans that are resistant to Bean golden mosaic virus are plants that have been rendered resistant by RNA interference technology, and are double-stranded RNA genes for replication proteins. By introducing (sense and antisense ac1 gene) and inhibiting the synthesis of replication protein of BGMV, it shows resistance to BGMV. Methods for producing such plants are generally known to the person skilled in the art and are described, for example, in the publications mentioned above.
  • anti-pathogenic substances examples include ion channel blockers (sodium channel blockers, calcium channel blockers, etc.); viral KP1, KP4 and KP6 toxins; stilbene synthase; bibenzyl synthase. Chitinase; glucanase; so-called "pathogenicity-related proteins"(PRP; see e.g. EP0392225); anti-pathogenic substances produced by microorganisms (e.g. peptide antibiotics, heterocyclic antibiotics (e.g. WO1995/033818; ) And protein factors or polypeptide factors involved in plant pathogen defense (so-called “plant disease resistance gene” described in WO2003/000906)).
  • ion channel blockers sodium channel blockers, calcium channel blockers, etc.
  • viral KP1, KP4 and KP6 toxins stilbene synthase
  • bibenzyl synthase Chitinase
  • glucanase so-called "pathogenicity-related proteins”
  • Anti-pathogenic substances produced by plants can protect the plant from various pathogenic microorganisms such as fungi, viruses and bacteria.
  • Useful plants of increasing interest in the context of the present invention include wheat (e.g. wheat, barley, rye and oats), soybean, corn, rice, rapeseed, pome fruit, drupe, peanuts, coffee, tea, strawberries. , Turf; vines and vegetables (for example, tomato, potato), Cucurbitaceae, papaya, melon, lentils (lenses) and lettuce, more preferably soybean, tomato, rice and wheat (for example wheat, barley, Rye and oats), and most preferably soybeans, rice and wheats (eg wheat, barley, rye and oats).
  • wheat e.g. wheat, barley, rye and oats
  • soybean, corn, rice, rapeseed, pome fruit, drupe peanuts, coffee, tea, strawberries.
  • Turf vines and vegetables (
  • plants having resistance to fungal pathogens include soybean having resistance to soybean rust fungus (Phakopsora pachyrhizi and Phakopsora meibomiae) (see, for example, WO2008/017706); Phytophthora infestans Solanaceae plants having resistance to cotton, tomato, potato and the like (see, for example, US5859332, US7148397, EP1334979); corn having resistance to Colletotrichum such as Colletotrichum graminicola (for example, US2006 /225152); Apples having resistance to apple scab (venturia inaequalis) (see, for example, WO1999/064600); Fusarium species (eg, fusarium graminearum, fusarium sporotrichioides, fusarium lateritium, fusarium pseudograminearum, fusarium sambucinum, fusarium) culmorum, fusarium poae, fusarium
  • plants having resistance to bacterial pathogens include, for example, rice having resistance to xylella fastidiosa (see, for example, US6232528); rice having resistance to bacterial blight fungus, cotton, Plants such as soybean, potato, sorghum, corn, wheat, barley, sugar cane, tomato and pepper (see, for example, WO2006/42145, US5952485, US5977434, WO1999/09151, WO1996/22375); Pseudomonas syringae Resistant tomatoes (see, for example, Can. J. Plant Path., 1983, 5:251-255).
  • plants having resistance to viral pathogens include, for example, drupes having resistance to plum pox virus (for example, plums, almonds, apricots, cherries, peaches, nectarines) (for example, US PP15154Ps, EP0626449); potatoes that have resistance to potato virus Y (see US5968828); potatoes, tomatoes, cucumbers that are resistant to tomato spotted wilt virus. And plants such as legumes (see, for example, EP0626449, US5973135); corn having resistance to maize streak virus (see, for example, US6040496); papaya ring spot virus (papaya ring spot virus).
  • cucumber virus resistance to papaya
  • cucumber plant having resistance to cucumber mosaic virus
  • solanaceous plant For example, potato, tobacco, tomato, eggplant, paprika, capsicum and pepper
  • Cucurbitaceae having resistance to watermelon mosaic virus 2 and zucchini yellow mosaic virus.
  • Plants for example, cucumber, melon, watermelon and pumpkin (see, for example, US6015942); Potato having resistance to potato leafroll virus (see, for example, US5576202); Potato virus X (potato virus X), Potato virus Y (potato virus Y), potatoes with broad resistance to viruses such as potato leafroll virus (see, for example, EP0707069); Bean golden mosaic virus (Bean golden mosaic virus) Common bean with resistance (See, for example, Mol Plant Microbe Interact. 2007 Jun;20(6):717-26.). Some plants are resistant to antibiotics such as kanamycin, neomycin and ampicillin.
  • the naturally occurring bacterial nptII gene expresses an enzyme that blocks the action of the antibiotics kanamycin and neomycin.
  • the ampicillin resistance gene ampR (also known as blaTEM1) is derived from the bacterium Salmonella paratyphi and is used as a marker gene in microbial and plant transformation. ampR is involved in the synthesis of beta-lactamase, an enzyme that neutralizes antibiotics in the penicillin group, including ampicillin.
  • Plants having resistance to antibiotics include, for example, potato, tomato, flax, canola, rapeseed, rapeseed and corn (e.g., Plant Cell Reports, 20, 2001, 610-615, Trends in Plant Science, 11, 2006, 317-319, Plant Molecular Biology, 37, 1998, 287-296, Mol Gen Genet., 257, 1998, 606-13. Plant Cell Reports, 6, 1987, 333-336, Federal. Register (USA), Volume 60, No. 113, 1995, 31139. Federal Register (USA), Volume 67, No. 226, 2002, 70392, Federal Register (USA), Volume 63, No. 88, 1998, 25194, Federal Register (USA), Volume 60, No.
  • the plants are selected from soybeans, tomatoes and wheats (e.g. wheat, barley, rye and oats), most preferably soybeans and wheats (e.g. wheat, barley, rye and oats).
  • soybeans, tomatoes and wheats e.g. wheat, barley, rye and oats
  • soybeans and wheats e.g. wheat, barley, rye and oats
  • R examples of available plants having resistance to plant viral diseases include, for example, papayas “Rainbow”, “SunUp”, and “Huanong No. 1 which have been given resistance to Papaya ringspot virus.
  • PLRV potato leaf curl virus
  • rice that has been given resistance to blast fungus (Magnaporthe oryzae); resistance to Rhizoctonia solani Applied rice; wheat with resistance to leaf rust (Puccinia triticina); wheat with resistance to yellow rust fungus (Puccinia striiformis f. sp. tritici); black rust fungus (Puccinia graminis f. sp) .Tritici) wheat with resistance to powdery mildew (Blumeria graminis f. sp.
  • udon powder was used by deleting the powdery mildew resistance gene (MILDEW RESISTACE LOCUS O, hereinafter abbreviated as MLO) using taren and crisper castine.
  • MLO powdery mildew resistance gene
  • the Rvi6 previously called HcrVf2
  • HcrVf2 apple mold disease
  • Apples that are resistant to mold disease see Plant Biotech.J., 12, 12, 2-9, 2014
  • the properties of the transgenic rootstocks that have the resistance to Prunus necrotic ringspot virus infection have been transferred to non-transgenic spikelets. 1328 (see 2014).
  • the quality modification of the product means an increase or decrease in the synthesis of the modified component or the synthesis amount of the component as compared with the corresponding wild type plant.
  • Plants with modified product quality include, for example, modified plants with increased or decreased content of vitamins, amino acids, proteins and starches, various oils, and modified plants with reduced nicotine content.
  • Plants whose product quality has been modified by gene recombination technology include, for example, the alfalfa-derived S-adenosyl-L-methionine: trans-caffeoyl CoA-3-methyltransferase (ccomt) gene double gene involved in lignin production.
  • ccomt trans-caffeoyl CoA-3-methyltransferase
  • Canola with increased glyceride content "Laurical(TM) Canola”; suppresses the gene expression by introducing a partial gene (gm-fad2-1) of ⁇ -6 desaturase derived from soybean which is a desaturase of fatty acid , Soybean “Plenish (trademark)” and “Treus (trademark)” with increased oleic acid content; and genes that generate double-stranded RNA of soybean-derived acyl-acyl carrier protein thioesterase gene (fatb1-A) , Soybean "Vistive Gold (trademark)” whose saturated fatty acid content was reduced by introducing a gene that produces double-stranded RNA of the soybean-derived ⁇ -12 desaturase gene (fad2-1A); Primrose-derived ⁇ -6 desaturase Genetically modified soybean in which stearidonic acid, which is one of the ⁇ 3 fatty acids, was produced by introducing the gene (Pj.D6D) and the delta
  • the rice that can be harvested to produce rice containing Vitamin A is Golden rice.
  • potato and corn having a modified amylopectin content see, for example, US6784338, US2007/0261136, WO1997/04471; canola, corn, cotton, grape, cattail having a modified oil content.
  • Cowpea (catalpa), rice, soybean, rapeseed, wheat, sunflower, bittern, safflower and vernonia plants (e.g., US7294759, US7157621, US5850026, US6441278, US5723761, US6380462, US6365802, US6974898, WO2001).
  • the plant is selected from soybean, canola, tomatoes, rice and wheat (eg wheat, barley, rye and oats), most preferably soybean, canola, rice, wheat and barley.
  • citrus fruits in which the characteristics of fruits by genomic selection for example, weight of fruits, fragrance, juiciness, and sugar content are modified are known (see Scientific Reports, 7, 4721 2017).
  • the plant whose nutrient utilization is modified includes, for example, a plant in which assimilation or metabolism of nitrogen or phosphorus is enhanced.
  • plants having enhanced nitrogen assimilation ability and nitrogen utilization ability by gene recombination technology include, for example, canola, corn, wheat, sunflower, rice, tobacco, soybean, cotton, alfalfa, tomato, wheat, potato, sugar beet, sugar cane.
  • rapeseed see, for example, WO1995/009911, WO1997/030163, US6084153, US5955651 and US6864405).
  • plants with improved phosphorus uptake by gene recombination technology include alfalfa, barley, canola, corn, cotton, tomato, rapeseed, rice, soybean, sugar beet, sugar cane, sunflower, wheat and potato (for example, See US7417181, US2005/0137386). Methods for producing such plants are generally known to the person skilled in the art and are described, for example, in the publications mentioned above.
  • the plants are selected from soybeans, tomatoes and wheats (eg wheat, barley, rye and oats), most preferably soybeans, rice, corn and wheat.
  • Examples of plants whose fertility traits, etc., have been modified by gene recombination technology include plants with male sterility and fertility recovery traits.
  • maize and chicory with male sterility traits by expressing a ribonuclease gene (barnase) derived from Bacillus amyloliquefaciens in anther tapetum cells; DNA adenine methylase gene (dam) derived from E.
  • barnase ribonuclease gene
  • Dam DNA adenine methylase gene
  • coli Maize to which a male sterility trait has been imparted by introduction a maize-derived alpha-amylase gene (zm-aa1) giving a male sterility trait and a ms45 protein gene (ms45) derived from corn giving a fertility recovery trait
  • Fertility trait was controlled by: maize; canola with fertility recovery function by expressing Bacillus ribonuclease inhibitor protein gene (barstar) in tapetum cells of anther; Bacillus giving male sterility trait Examples thereof include canola whose fertility trait is controlled by expressing a ribonuclease gene (barnase) derived from the bacterium and a ribonuclease inhibitor protein gene (barstar) derived from Bacillus that gives a trait for recovering fertility.
  • plants that have been given fertility traits by gene recombination technology include tomato, rice, mustard, wheat, soybean and sunflower (for example, US6720481, US6281348, US5659124, US6399856, US7345222, US7230168, US6072102, EP1135982, WO2001. /092544 and WO 1996/040949).
  • Methods for producing such plants are generally known to the person skilled in the art and are described, for example, in the publications mentioned above.
  • the plant is selected from corn, canola, soybean, tomatoes and wheats (eg wheat), most preferably corn, canola, soybean, rice, wheat.
  • Plants endowed with abiotic stress tolerance have limited drought, high salinity, high light intensity, high UV irradiation, chemical pollution (e.g. high heavy metal concentrations), low or high temperatures, limited nutrients (i.e. nitrogen, phosphorus). It is a plant that exhibits increased tolerance to abiotic stress conditions such as feeding and population stress (see, for example, WO2000/004173, WO2007/131699, CA2521729 and US2008/0229448).
  • plants to which abiotic stress tolerance has been imparted by gene recombination technology include, for example, rice resistant to drought, corn, soybean, sugar cane, alfalfa, wheat, tomato, potato, barley, rapeseed, beans, oats, sorghum. And cotton (see, for example, WO2005/048693, WO2008/002480, and WO2007/030001); corn, soybean, wheat, cotton, rice, rapeseed, and alfalfa (see, for example, US4731499 and WO2007/112122) that are resistant to low temperatures.
  • High salt-tolerant rice, cotton, potato, soybean, wheat, barley, rye, sorghum, alfalfa, grape, tomato, sunflower and tobacco see, for example, US7256326, US7034139, WO/2001/030990.
  • corn "Drought Gard (registered trademark)" Monsanto product in which a cold shock protein gene cspB of Bacillus subtilis has been introduced.
  • corn having drought tolerance is "Agrisure Artesian (registered trademark)” and "Optimum ( It is developed under the product name of "Registered trademark) AQUAmax (registered trademark)”.
  • Modifications of maturation characteristics include, for example, delayed maturation, delayed softening and premature maturation.
  • Examples of plants whose maturation characteristics have been modified by gene recombination technology include, for example, the S-adenosylmethionine hydrolase gene (sam-K) derived from Escherichia coli bacteriophage T3, which is related to ethylene production of plant hormones, and has a shelf life.
  • deficient ACC synthase gene from Pseudomonas chlororaphis which is a gene lacking a part of the tomato-derived ACC synthase gene involved in the plant hormone ethylene production ,
  • tomatoes with improved shelf life by introducing a gene pg that generates double-stranded RNA of polygalacturonase gene derived from tomato "FLAVR SAVR (trademark)" can be mentioned.
  • plants whose maturation characteristics have been modified by gene recombination technology include, for example, tomato, melon, raspberry, strawberry, muskmelon, pepper and papaya with delayed ripening (for example, US 5767376, US7084321, US6107548, See US5981831, WO1995/035387, US5952546, US5512466, WO1997/001952, WO1992/008798 and PlantCell.1989,53-63. PlantMolecularBiology, 50, 2002). Methods for producing such plants are generally known to the person skilled in the art and are described, for example, in the publications mentioned above.
  • the plants are fruits (eg tomatoes, vines, melons, papayas, bananas, peppers, raspberries and strawberries); drupes (eg cherries, apricots and peaches); Pear); and citrus fruits (e.g., citron, lime, orange, pomelo, grapefruit, and mandarin), and more preferably selected from tomato, melon, papaya, vine, apple, banana, orange, and strawberry, Most preferred are tomato, melon and papaya.
  • fruits eg tomatoes, vines, melons, papayas, bananas, peppers, raspberries and strawberries
  • drupes eg cherries, apricots and peaches
  • Pear e.g., citron, lime, orange, pomelo, grapefruit, and mandarin
  • Examples of plants to which other quality alterations have been imparted by gene recombination technology include, for example, by introducing a 3-phytase gene (phyA) derived from Aspergillus niger, which is a phytic acid-degrading enzyme of plants.
  • phyA 3-phytase gene
  • Canola “Phytaseed (registered trademark) Canola” with enhanced decomposition of phytic acid; dihydroflavonol-4-reductase gene derived from petunia (Petunia hybrida) that is an enzyme that produces blue pigment delphinidin and its derivatives, and petunia, Carnations "Moondust (trademark)” and “Moonshadow” whose flower color is controlled to be blue by introducing flavonoid-3',5'-hydroxylase gene derived from pansy (Viola wittrockiana), salvia (Salvia splendens) or carnation.
  • -A rose whose flower color was controlled to blue by introducing a hydroxylase gene; a rice plant that has a hay fever alleviating effect through immunotolerance by introducing a modified cedar pollen antigen protein gene (7crp); Maize with enhanced degradation of endogenous phytic acid by introducing 3-phytase gene (phyA); Produces high quality fiber with improved fiber micronaire, increased fiber strength, length uniformity and color Cotton (see, for example, WO1996/26639, US7329802, US6472588 and WO2001/17333).
  • Examples of plants whose traits related to growth and yield have been modified include plants with enhanced growth ability.
  • Examples of plants whose traits related to growth and yield have been modified by gene recombination technology include, for example, the growth of plants is enhanced by introducing a gene (bbx32) encoding a transcription factor that regulates diurnal origin from Arabidopsis thaliana, As a result, soybean with high yield can be expected; by introducing a transcription factor gene (athb17) belonging to homeodomain-leucine 14 zipper (HD-Zip) family class II HD-Zip II) derived from Arabidopsis thaliana, the ear weight increases. As a result, corn has been developed with high yield expected.
  • a zinc finger nuclease was used to delete the IPK1 gene encoding inositol-1,3,4,5,6-pentakisphosphate2-kinase, which is an enzyme of phytic acid biosynthesis.
  • Loss of phytic acid reduced the corn "ZFN-12 maize”; by using Crisper Cassine, the gene encoding polyphenol oxidase was deleted to impart browning resistance. Mushrooms (see Nature., Vol. 532, 21 APRIL 2016).
  • the low polyphenoloxidase (enzyme that causes browning)-producing gene sequence GEN-03 isolated from apple should be introduced into a new apple variety.
  • “Arctic (registered trademark)” an apple with reduced polyphenol oxidase expression that does not turn brown; a salt-resistant tomato stand as an example that gives panicles the properties of GM rootstock that is a breeding technology that uses grafting Examples include tomatoes that are salt-resistant to non-transgenic scion tomatoes using trees (see Physiol Plantarum, 124, 465-475 2005).
  • genes that show resistance to many diseases, pests and abiotic stress are known, and resistant varieties into which they are introduced are actively produced.
  • Diseases in rice and as genes showing resistance to abiotic stress, for example, BPH1, BPH2, BPH3, BPH4, BPH5, BPH6, BPH7, BPH8, BPH9, BPH10, BPH11, BPH12, BPH13, BPH14, BPH15, BPH17.
  • sesame leaf blight disease resistance gene YDV, etc. yellow dwarf disease resistance gene; BSV, etc. black stripe dwarf disease resistance gene; Amy1A, Amy1C , Amy3A, Amy3B and other high temperature ripening resistance genes; dul3, qAC9.3, rsr1, Wx and Wx1-1 and other low amylose genes; AP01, SCM2, Sd1 and other lodging resistance genes; Sdr4 and other germination resistance Gene; low temperature resistance gene such as CTB1, CTB2, qLTG3-1; drought resistance gene such as Dro1; DEP1, Cn1a, GPS, SPIKE, PTB1, TAWAWA1, WFP, IPA1, Genes related to paddy number or seed form such as GS3, GS5, GS6, GL3.1, GW2, GW8, qGL3, qSS7, qSW5; genes that regulate daylength responsiveness such as Hd1, Ghd8, DTH8; FLO4, PDIL1 etc.
  • the endosperm quality gene of L.; LOX3 and other lipoxygenase deficient (reducing old rice odor) genes; and the gene related to amylopectin chain length such as Alk are known. Rice cultivars in which one or more of these genes are simultaneously incorporated have been developed or marketed.
  • cotton resistant to both glufosinate and 2,4-D cotton resistant to both glufosinate and dicamba; corn resistant to both glyphosate and 2,4-D; glyphosate and HPPD herbicides Soybean resistant to both; maize resistant to glyphosate, glufosinate, 2,4-D, allyloxyphenoxypropionic acid (FOPs) herbicides and cyclohexadione (DIMs) herbicides has also been developed.
  • FOPs allyloxyphenoxypropionic acid
  • DIMs cyclohexadione
  • Examples of commercially available plants endowed with herbicide resistance and/or pest resistance include, for example, corn having glyphosate resistance and resistance to corn borer "YieldGard Roundup Ready (trademark)” and “YieldGard Roundup Ready 2 (trademark)”.
  • Maize having glufosinate resistance and corn borer resistance "Agrisure CB/LL (trademark)”; Maize having glyphosate resistance and corn rootworm resistance "Yield Gard VT Root worm/RR2 (trademark)”; glyphosate resistance and Corn “Yield Gard VT TripleTM” with resistance to corn rootworm and corn borer; glufosinate resistance and lepidopteran pest resistance (Cry1F) (eg Western Bean Cut Worm, Corn Borer, Black Cut Worm and Fall) (Herculex I(TM)) having resistance to armyworms; Yield Gard Corn Rootworm/Roundup Ready 2(TM) having glyphosate resistance and corn rootworm resistance; Glufosinate resistance and corn Coleoptera Pest resistance (Cry3A) (eg resistance to Western corn rootworm, Northern corn rootworm and Mexican corn rootworm) and corn "Agrisure GT/RWTM”; glufosinate resistance and Coleoptera pest resistance ( Cry34/35Ab1) (
  • Examples of commercially available plants imparted with disease resistance and pest resistance include, for example, potato “Hi-Lite New Leaf (trademark) Y, which has been given potato virus Y (Potatovirus Y) resistance and pest resistance. Potato”, “NewLeaf (trademark) YRusset Burbank Potato” and “Shepody NewLeaf (trademark) Y Potato”; potato "NewLeaf (trademark) Plus” with potato cigar virus (Potato leafleaf virus) resistance and pest resistance Russet Burbank Potato”.
  • herbicide tolerance and product quality modification Commercially available plants endowed with the properties of herbicide tolerance and product quality modification include, for example, canola “InVigorTM Canola” endowed with glufosinate resistance and fertility trait; endowed with glufosinate tolerance and fertility trait.
  • Maize “InVigor (trademark) Maize”; soybean “Vistive Gold (trademark)” to which glyphosate tolerance is imparted and oil content is modified.
  • Examples of commercially available plants with three or more traits include glyphosate resistance, glufosinate resistance and lepidopteran pest resistance (Cry1F) (i.e., against Western bean cut worms, corn borers, black cut worms and fall army worms).
  • glyphosate resistance i.e., against Western bean cut worms, corn borers, black cut worms and fall army worms.
  • the commercially available or developed plants are listed below (A1 to A550).
  • the inside of parentheses means [plant name, Event Name, Event code, trademark name (Tradename)].
  • NA means "no information” or "unavailable information”.
  • Many of these plants are registered database (GM APPROVAL DATABASE) in the electronic information site (http://www.isaaa.org/) of the International Agri-Bio Enterprise (INTERNATINAL SERVICE for the ACQUISITION of AGRI-BIOTECH APPLICATIONS, ISAAA). It is listed in.
  • A1 [Alfalfa, J101, MON-00101-8, Roundup Ready (trademark) Alfalfa]
  • A2 [Alfalfa, J101 x J163, MON-00101-8 x MON-00163-7, Roundup Ready (trademark) Alfalfa],
  • A3 [Alfalfa, J163, MON-00163-7, Roundup ReadyTM Alfalfa],
  • A4 [Alfalfa, KK179, MON-00179-5, HarvXtraTM],
  • A6 [Apple, GD743, OKA-NB001-8, ArcticTM "Golden Delicious” Apple]
  • A7 [Apple, GS784, OKA-NB002-9, Arctic (Trademark)]
  • A8 [apple, NF872, OKA-NB003-1, Arctic(trademark
  • A191 [corn, BT11 x MIR162 x MIR604 x 5307, SYN-BT011-1 x SYN-IR162-4 x SYN-IR604-5 x SYN-05307-1, NA]
  • A192 [corn, Bt11 x MIR162 x MIR604 x 5307 x GA21, SYN-BT011-1 x SYN-IR162-4 x SYN-IR604-5 x SYN-05307-1 x MON-00021-9, NA]
  • A193 [corn, Bt11 x MIR162 x MIR604 x GA21, SYN-BT011-1 x SYN-IR162-4 x SYN-IR604-5 x MON-00021-9, Agrisure® Viptera® 3111, Agrisure® Viptera( Trademark) 4],
  • A194 [corn, Bt11 x MIR162 x MIR60
  • DAS-40278-9 EnlistTM Maize
  • A221 [corn, DAS40278 x NK603, DAS-40278-9 x MON-00603-6, NA]
  • A222 [corn, DBT418, DKB-89614-9.
  • A354 [corn, TC1507 x MON810, DAS-01507-1 x MON-00, NA]
  • A355 [corn, TC1507 x MON810 x MIR162, DAS-01507-1 x MON-00810 -6 x SYN-IR162-4, NA]
  • A356 [corn, TC1507 x MON810 x MIR162 x NK603, DAS-01507-1 x MON-00810-6 x SYN-IR162-4 x MON-00603-6, NA]
  • A357 [corn, TC1507 x MON810 x MIR604, DAS-01507-1 x MON-00810-6 x SYN-IR604-5 , NA]
  • A358 [corn, TC1507 x MON810 x NK603, DAS-01507-1 x MON-00810-6 x x
  • insecticidal active compounds can be used in combination in the composition of the present invention or the method of the present invention.
  • the term “combination” includes mixed use, mixed treatment, and sequential treatment, and in the case of sequential treatment, the order is not particularly limited.
  • Examples of the insecticidal active compound include the following.
  • the number in parentheses represents the CAS registration number.
  • Sodium channel modulators acrinathrin, allethrin, bifenthrin, bifenthrin, kappa-bifenthrin, bioallethrin, bioresmethrin, bioresmethrin, cycloprothrin, cyfluthrin.
  • cyfluthrin beta-cyfluthrin, beta-cyfluthrin, cyhalothrin, gamma-cyhalothrin, lambda-cyhalothrin, lambda-cyhalothrin, cypermethrin, alpha-cypermethrin , Beta-cypermethrin, beta-cypermethrin, theta-cypermethrin, zeta-cypermethrin, cyphenothrin, deltamethrin, empenthrin, es Fenvalerate, etofenprox, fenpropathrin, fenvalerate, flucythrinate, flumethrin, fluvalinate, taufluvalinate fluvalinate), halfenprox (halfenprox), heptafluthrin (heptafluthrin), imiprothrin (imiprothrin), kades
  • Nicotinic acetylcholine receptor antagonist modulator acetamiprid, clothianidin, dinotefuran, imidacloprid, nitenpyram, thiacloprid, thiamethoxatine, thiamethnicom, thiamethoxam.
  • Chitin biosynthesis inhibitor bistrifluron bistrifluron
  • fluazuron fluazuron
  • chlorfluazuron chlorfluazuron
  • diflubenzuron diflubenzuron
  • flucycloxuron flucycloxuron
  • fluphenoxuron flufenoxuron
  • hexaflu Muron hexaflumuron
  • lufenuron lufenuron
  • novalron novaluron
  • noviflumuron noviflumuron
  • teflubenzuron triflumuron (buflufezin), buprofezin.
  • Mitochondrial electron transport system complex II inhibitor such as cienopyrafen, cyflumetofen, and pyflubumide.
  • Microbial-derived insect midgut intestinal disruption agent Insecticidal protein products derived from Bacillus thuringiensis (Cry1Ab, Cry1Ac, Cry1Fa, Cry1A.105, Cry2Ab, Vip3A, mCry3A, Cry3Ab, Cry3Bb, Cry34Ab1/Cry35Ab1), Bacillus sp.
  • Bacillus sphaericus 2362 strain Bacillus sphaericus, strain:2362, ABTS1743 (trade name: VectoMax), Serotype H5a5b
  • Bacillus thuringiensis Bacillus thuringiensis, strain:AQ52, BD#32, CR-371) Bacillus ⁇ Thuringiensis subsp. Aizawai, strain: ABTS-1857 (trade name: XenTari), AM65-52, GC-91 (trade name: Agree/Turex/Able), Serotype H-7 (trademark) Name: Florbac WG) etc.
  • Kurstaki (Trade name: Asututo,Turilav WP), strain: ABTS351, BMP123 (Trade name: Baritone Bio-Insecticide), EG234, EG7841 (Trade name: Crymax), EVB113-19 (Trade name: Bioprotec-CAF), F810, HD-1 (Trade name: Dipel ES), PB54, SA-11 (Trade name: Javelin), SA-12 (Trademark) Name: Deliver/CoStar, Thuricide) etc.), Bacillus thuringiensis subsp. Tenebriosis, strain: NB 176 (trade name: Bacillus thuringiensis subsp. morrisoni), Bacillus thuringiensis subsp.
  • Bacillus thuringiensis subsp. Thuringiensis strain: MPPL 002
  • Bacillus thuringiensis subsp. var. colmeri trade name: TianBaoBtc
  • Bacillus thuringiensis subsp. var. darmstadiensis strain: 24-91, etc.
  • Bacillus thuringiensis dendrolimus variety Bacillus thuringiensis subsp. var. dendrolimus
  • Bacillus thuringiensis galleria variety Bacillus thuringiensis subsp. var. galleriae
  • Bacillus thuringiensis islaelensis variety Bacillus suburing. var.
  • Bacillus thuringiensis japonensis varieties buibui strain (Bacillus thuringiensis subsp. var. japonensis buibui), Bacillus thuringiensis aji Variant (Bacillus thuringiensis subsp. var.aegypti), Bacillus thuringiensis var. 7216, Bacillus thuringiensis var. sandiego, strain: M-7 (trade name: M- Ome) etc.), Bacillus thuringiensis var. T36).
  • Pasteuria penetrans trade name: Pasteuria, etc.
  • Pasteuria thoynei Pasteuria usgae
  • Econem Serratia entomophila
  • Verticillium chlamydosporium Verticillium lecani
  • strain:NCIM1312 trade name: MEALIKIL
  • Adoxophyes orana granulosis virus Adoxophyes orana granulosis virus
  • Anticalcia gemmatalis nuclear polyhedrosis virus Anticarsia gemmatalis mNPV
  • Autographa californica nuclear polyhedrosis virus FV#11 Autographa californica nuclear polyhedrosis virus FV#11
  • Sysia pomonella granule disease virus V15 Cydia pomonella GV V15
  • Cydia pomonella GV V22 Cryptophlebia leucotreta GV
  • synergists may be used in combination in the composition of the present invention or the method of the present invention.
  • the term “combination” includes mixed use, mixed treatment, and sequential treatment, and in the case of sequential treatment, the order is not particularly limited. Specific examples of the synergist are shown below.
  • the bactericidal active compound (group (a)) is a nucleic acid synthesis inhibitor (eg, phenylamide-based bactericide, acylamino acid-based bactericide), cell division and cytoskeleton inhibitor (eg, MBC bactericide), respiratory inhibitor (Eg, QoI fungicide, QiI fungicide, SDHI fungicide), amino acid synthesis and protein synthesis inhibitor (eg, anilinopyridine fungicide), signal transduction inhibitor, lipid synthesis and membrane synthesis inhibitor, sterol biosynthesis Inhibitors (eg, DMI fungicides such as triazoles), cell wall synthesis inhibitors, melanin synthesis inhibitors, plant defense inducers, multi-acting point contact active fungicides, microbial fungicides, microbial fungicide, a nucleic acid synthesis inhibitor (eg, phenylamide-based bactericide, acylamino acid-based bactericide), cell division and cytoskeleton inhibitor (eg, M
  • Chlorothalonil chlorozolinate, chlezolinate, colletochlorin B, copper(II) acetate, copper(II) hydroxide, basic copper chloride ( copper ox ychloride), copper(II) sulfate, coumoxystrobin, cyazofamid, cyflufenamid, cymoxanil, cyproconazole, cyprodinil , Dichlobentiazox, dichlofluanid, dichlofluanid, diclocymet, diclomezine, dichloran, diethofencarb, diphenoconazole, diflunoimazole, diflumetrim, diflumetrim, diflumetor.
  • Bacillus amyloliquefaciens strain: AT332, B3, D747 (trade name: Bacstar, Double Nickel), DB101 (trade name: Shelter), DB102 (trade name: Artemis), FZB24, FZB42 (trademark) Name: RhizoVital), GB03 (trade name: Kodiak), IN937a, MBI600 (trade name: Subtilex), QST713, isolate B246, F727 (trade name: Stargus), etc.), Bacillus licheniformis, strain: HB-2 (Brand name: Biostart, Rhizoboost), SB3086 (Brand name: EcoGuard, Green Releaf), Bacillus pumilus (Bacillus pumilus, strain: AQ717, BUF-33 (Brand name: Integral F-33), GB34 (Brand name) : Yield Shield), QST2808 (trade name: Sonata, Ballad Plus) etc.), Bacillus simplex (Bacillus simplex (B
  • Amyloliquefaciens strain: FZB24, etc.
  • Burkholderia cepacia trade name: Deny, Intercept, Blue Circle
  • Burkholderia cepacia type Wisconsin strain: M54, J82 etc.
  • Candida oleophila strain: O etc.
  • Candida saitoana Candida saitoana, trade name: Bio-Coat, Biocure etc.
  • Cartobora Erwinia carotovora sunsp.Cartovora, strain: CGE234M403 (trade name: biokeeper), etc.
  • Fusarium oxysporum (strain: Fo47, trade name: Fusaclean, BiofoxC, etc.)
  • Gliocladium catenulatum (Gliocladium catenulatum, strain: J1446 (trade name: primastop, Prestop), etc.)
  • Paenibacillus polymyxa strain: AC-1 (trade name: Topseed), BS-0105 etc.)
  • Pantair Agglomerans Pantoea agglomerans, strain: E325 etc.
  • Flebiopsis gigantea (trade name: Rotstop, strain: VRA1992 etc.)
  • Pseudomonas aureofaciens (strain: TX-1 etc.)
  • Pseudomonas chlororafis Pseudomonas chlororaphis, strain
  • CAB-02 strain (Pseudomonas sp. CAB-02), Pseudomonas syringae strain (Pseudomonas syringae, strain: 742RS (trade name: Frostaban C), MA-4 (trade name: Bio-Save), Pseudozyma flocculosa, strain: PF-A22UL (trade name: Sporadex L), Pythium oligandrum, strain: DV74 (trade name) : Polyversum) etc.), Streptomyces griseoviridis (strain: K61 etc.), Streptomyces lydicus (Streptomyces lydicus, strain: WYCD108US, WYEC108 (trade name: Actinovate) etc.), Tararomices flavus SAY-Y -94-01 strain (Talaromyces flavus, strain: SAY-Y-94-01 (trade name: tough block), V117b (trade name: Protus
  • a step of treating a crop seed with one or more compounds selected from the compound group A, and/or a one or more compounds selected from the compound group B in a growing season of the crop may be included.
  • the compound group A is a neonicotinoid compound, a diamide compound, a carbamate compound, an organophosphorus compound, a biological nematicide compound, other insecticide compounds and nematicide compounds, and It is a group consisting of azole compounds, strobilurin compounds, metalaxyl compounds, SDHI compounds, other fungicide compounds and plant growth regulators.
  • examples of the neonicotinoid compound used for treating the crop seeds include the following. Clothianidin (clothianidin), imidacloprid (imidacloprid), nitenpyram (nitenpyram), acetamiprid (acetamiprid), thiamethoxam (thiamethoxam), Furupirajifuron (flupyradifurone), sulfo hexa Flor (sulfoxaflor), triflupromazine meso pyridinium beam (triflumezopyrim), dichloro meso thia's (Dicloromezotiaz ), thiacloprid and dinotefuran.
  • examples of the diamide compound used for treating the crop seed include the following. Flubendiamide, chlorantraniliprole, cyantraniliprole, cyclananiliderole, broflanilide rolls, brofuranilide rolls, broflanilide rolls, brofuranilide rolls, and brofuranilide rolls.
  • the carbamate-based compound to be treated on the crop seeds includes the following. Aldicarb, oxamyl, thiodicarb, carbofuran, carbosulfan and dimethoate.
  • cadusafos cadusafos
  • chlorpyrifos chlorpyrifos
  • Chlorpyrifos Heterohosu
  • Heterofos Mekaruhon (mecarphon)
  • phorate phorate
  • Chionajin thionazin
  • triazophos triazophos
  • Jiamidahosu diamidafos
  • fosthietan fosthietan
  • phosphamidon phosphamidon
  • examples of the biological nematicide compound to be treated on the crop seed include the following. Harpin Protein, Pasteuria nishizawae, Pasteuria penetrans, Pasteuria usage, Myrothecium verrucaria, Burholderia cepacia, Bacillus chitonosporus, Paecilomyces lilacinus, Bacillus amyloliquefaciens, Bacillus firmus, Bacillus subtilis, Bacillus pumulus, Trichoderma harzianum, Hirsutella rhossiliensis, Hirsutella minnesotensis, Verticillium chlamydosporum and Arthrobotrys Dactyloides ..
  • the other insecticide compounds and nematicide compounds to be treated on the crop seeds include the following. Fipronil (fipronil), ethiprole (ethiprole), beta-cyfluthrin (beta-cyfluthrin), tefluthrin (tefluthrin), chlorpyrifos (chlorpyrifos), abamectin (abamectin), spirotetramat (spirotetramat), Chiokisazafen (tioxazafen), full azaindolizine (Fluazaindolizine), fluensulfone and fluxamethamide.
  • examples of the azole compound used for treating the seeds of crops include the following. Azaconazole, bittertanol, bromconazole, cyproconazole, difenoconazonef diconecone phenecoconazole, difeneconeol, diphenoconasol, diniconazole, diniconazol Nizole (fluquinconazole, flusilazole), flutriafol, hexaconazole (hexaconazole), imibenconazole (microcone), ipconazole (tomato), ipconazole (tomato), ipconazole (to), , Propiconazole, prothioconazole, simeconazole, tebuconazole, tetraconaazole, tetraconiazole, triazimenol, triazimenol, triazimenol, triazimenol, triazimenol,
  • examples of the strobilurin compound used to treat the crop seed include the following. Kresoxim-methyl, azoxystrobin, trifloxystrobin, fluoxastrobin, picoxystrobin, pyraclostrobin, pyraclostrobin, pyraclostrobin Strobin, diribencarb, metaminostrobin, orysastrobin and mandestrobin.
  • examples of the metalaxyl compound used for treating the seeds of crops include the following. Metalaxyl and metalaxyl-M (mefaxyl-M or mefenoxam).
  • the SDHI compounds to be treated on the crop seeds include the following. Sedaxane, Penflufen, Carboxin, Boscalid, Furametpyr, Flutolanil, Fluxapyroxapyrampyramyupuram, Isopyrazora, Isopirazam, Isopirazam, Isopirazam, Isopirazam, Isopirazam, Isopirazam, Isopirazam, Isopirazam, Isopyrazamom (Isofetamide), pyraziflumid, pyridiflumethofen, N-(7-fluoro-1,1,3-trimethylindan-4-yl)-1-methyl-3-difluoromethylpyrazole-4- Carboxylic amide (racemic or enantiomer, mixture of enantiomers in R form and enantiomer in S form in any ratio, and compound having enantiomeric ratio of R form/S form of 80/20 or more in R form rich
  • examples of the plant growth control agent to be used for treating crop seeds include the following. Ethephon, chlormequat-chloride, mepiquat-chloride, 4-oxo-4-(2-phenylethyl)aminobutyric acid (hereinafter sometimes referred to as compound 2).
  • examples of the other fungicide compound used for treating the crop seeds include the following. Tolclophos-methyl, thiram, captan, carbendazim, thiophanate-methyoxyl, azocob, mancozeb, thiabendazole, thiabend, thiabend, thiabend. , Picarbutrazox, and oxathiapiproline.
  • All the compounds constituting the above compound group A are known compounds, which can be synthesized based on known technical literature, or commercially available formulations or standard products can be purchased and used.
  • the compound group B is a strobilurin compound, an azole compound, an SDHI compound, another fungicide compound, a pyrethroid compound, a benzoylphenylurea compound, an organophosphorus insecticide compound, a neonicotinoid compound and a diamide. It is a group consisting of system compounds.
  • examples of the strobilurin compound for foliar treatment of agricultural products include the following. Pyraclostrobin, azoxystrobin, mandestrobin, trifloxystrobin and picoxystrobin.
  • the azole compounds for foliar treatment of agricultural products include the following. Prothioconazole, epoxyconazole, tebuconazole, cyproconazole, propiconazole, metconazole, bromuconazole, tetraconazole, triticonazole, ipphentrifluconazole and mefentrifluconazole.
  • the SDHI compounds for foliar treatment of agricultural products include the following. Benzobindiflupyr, Bixafen, Fluxapyroxad, F9990 and Compound 1.
  • examples of the other fungicide compound for foliar treatment of agricultural products include the following. Tolclofos-methyl and ethaboxam.
  • examples of pyrethroid compounds for foliar treatment of agricultural products include the following. Bifenthrin, lambda cyhalothrin, gamma cyhalothrin, cypermethrin, fenpropatrine, etofenprox, silafluofen and esfenvalerate.
  • the benzoylphenylurea compound for foliar treatment of agricultural products includes the following. Teflubenzuron and Triflumuron.
  • organophosphorus insecticide compound for foliar treatment of agricultural crops include the following. Acephate and Methomil.
  • examples of the neonicotinoid compound for foliar treatment of agricultural crops include the following. Imidacloprid, clothianidin, thiamethoxam, sulfoxaflor, flupyrazifron, triflumezopyrum and dichloromesozothiaz.
  • examples of the diamide compound for foliar treatment of agricultural products include the following. Flubendiamide, chlorantraniliprole, cyantraniliprole, brofuranilide, tetraniliprole and cyhalodiamide.
  • All the compounds constituting the above compound group B are known compounds, which can be synthesized based on known patent documents, and commercially available formulations or standard products can be purchased and used.
  • the compound A is usually a carrier such as a solid carrier or a liquid carrier.
  • a carrier such as a solid carrier or a liquid carrier.
  • the mixture is mixed, and if necessary, an auxiliary agent for formulation such as a surfactant is added to prepare a formulation for use.
  • the preferred dosage form is an aqueous liquid suspension formulation.
  • a preparation composed of a single component may be used alone or in combination of two or more kinds, or a preparation composed of two or more kinds of plural components may be used.
  • the amount of compound A to be treated is usually 0.2 to 5000 g, preferably 0.5 to 1000 g per 100 kg of crop seeds.
  • Examples of the method for treating the crop seeds with the compound A include, for example, a method of dressing the crop seeds with a preparation containing the compound A, a method of immersing the crop seeds in the preparation containing the compound A, and a preparation containing the compound A. Examples include spraying the seeds and coating the crop seeds with a mixture of compound A and a carrier.
  • compound X and compound Y are applied to a place where weeds are or will be occurring.
  • Examples of the method of applying the compound X and the compound Y include a method of applying the composition of the present invention to soil and a method of applying the composition of the present invention to weeds.
  • Spraying is usually carried out by diluting the composition of the present invention with water, and the amount of sprayed water is not particularly limited, but is usually 50 to 1000 L/ha, preferably 100 to 500 L/ha, more preferably 140 to 300 L/ha. Is.
  • the application amount of compound X and compound Y is usually 1 to 5000 g per 10,000 m 2 , preferably 2 to 2000 g per 10,000 m 2 , and more preferably 5 to 1000 g per 10,000 m 2 , as the total amount of compound X and compound Y.
  • compound X and compound Y may be mixed with an adjuvant before application.
  • the type of adjuvant is not particularly limited, but oil type such as Agri-Dex and MSO, nonion type (ester or ether of polyoxyethylene) such as Induce, anion type (substituted sulfonate) such as Gramine S, Genamin T Examples thereof include cation type (polyoxyethylene amine) such as 200BM and organic silicon type such as Silwet L77.
  • oil type such as Agri-Dex and MSO
  • nonion type esteer or ether of polyoxyethylene
  • anion type substituted sulfonate
  • Gramine S Genamin T
  • cation type polyoxyethylene amine
  • organic silicon type such as Silwet L77.
  • the pH and hardness of the spray liquid prepared when applying the compound X and the compound Y are not particularly limited, but are usually in the range of pH 5-9, and the hardness is usually in the range of 0 to 500.
  • the time period for applying the compound X and the compound Y is not particularly limited, but it is usually in the range of 5 am to 9 pm, and the photon flux density at the application site is usually 10 to 2500 ⁇ mol/square meter/second.
  • the spray pressure when applying the compound X and the compound Y is not particularly limited, but is usually 30 to 120 PSI, preferably 40 to 80 PSI.
  • the nozzle specified for application of the compound X and the compound Y in the method of the present invention may be a flat fan nozzle or a drift reduction nozzle.
  • flat fan nozzles include Teejet's Teejt110 series and XR Teejet110 series. These are normal spray pressures, typically 30-120 PSI, and the volume median diameter of the droplets ejected from the nozzle is usually less than 430 microns.
  • the drift reduction nozzle is a nozzle in which drift is reduced as compared with a flat fan nozzle, and is a nozzle called an air induction nozzle or a pre-orifice nozzle.
  • the volume median diameter of the droplets ejected from the drift reduction nozzle is usually 430 microns or more.
  • the air induction nozzle has an air introduction part between an inlet (chemical solution introduction part) and an outlet (chemical solution discharge part) of the nozzle and forms air-filled droplets by mixing air into the chemical solution.
  • TTI11004 Green Leaf Technology's TDXL11003-D, TDXL11004-D1, TDXL11005-D1, TDXL11006-D, Teejet's TTI110025, TTI11003, TTI11004, TTI11005, TTI11006, TTI11008, Pentair's ULD120-041, ULD120. -051, U
  • the inlet of the nozzle (chemical solution inlet) is a metering orifice, which limits the flow rate into the nozzle and lowers the pressure in the nozzle to generate large droplets. It is a nozzle to be formed. According to this, the pressure at the time of discharge is approximately halved compared to that before introduction.
  • the pre-orifice nozzle include DR110-10, UR110-05, UR110-06, UR110-08, UR110-10 manufactured by Wilger, and 1/4TTJ08 Turf Jet, 1/4TTJ04 Turf Jet manufactured by Teejet.
  • the composition of the present invention When the composition of the present invention is applied to a crop field, the composition of the present invention may be applied before sowing of crop seeds, or the composition of the present invention may be applied simultaneously with and/or after sowing of crop seeds. Good. That is, as the number of times of application of the composition of the present invention, the seeds of the crop can be sown one time before seeding, at the same time as seeding, or after seeding, twice except before seeding, twice except at the same time sowing, and 2 after seeding. And 3 times applied at any timing.
  • composition of the present invention When the composition of the present invention is applied before sowing of crop seeds, 50 days before sowing to immediately before sowing, preferably 30 days before sowing to immediately before sowing, more preferably 20 days before sowing to immediately before sowing, further preferably before sowing
  • the composition of the present invention is applied from 10 days to immediately before sowing.
  • the composition of the present invention is usually applied immediately after sowing to before flowering. More preferably, it is immediately after sowing to before emergence and/or between the true leaves 1 to 6 of the crop.
  • the case where the composition of the present invention is applied at the same time as sowing of the crop seeds is a case where the seeder and the sprayer are integrated.
  • compound X and compound Y are sequentially applied to a crop field, they are applied at least once in each step from seeding of crop seeds to before flowering, and the order is not limited.
  • the number of times of application of the compound X is 1 time before sowing of crop seeds, at the same time of sowing, or 1 time after sowing, 2 times excluding before sowing, and simultaneous sowing. Excluding 2 times, 2 times except after seeding, 3 times applying at any timing, and the like.
  • the number of times of application of the compound Y may be one time before sowing of crop seeds, at the same time as sowing, or after sowing, twice except before sowing, and at the same time sowing. Excluding 2 times, 2 times except after seeding, 3 times applying at any timing, and the like.
  • the compound X and the compound Y are sequentially applied to a crop field, when the compound X is applied before sowing of crop seeds, 50 days before sowing to immediately before sowing, preferably 30 days before sowing to immediately before sowing, more preferably Compound X is applied 20 days before sowing to immediately before sowing, more preferably 10 days before sowing to immediately before sowing.
  • the compound X and the compound Y are sequentially applied to a crop field
  • the compound Y when the compound Y is applied before sowing of crop seeds, 50 days before sowing to immediately before sowing, preferably 30 days before sowing to immediately before sowing, more preferably Compound Y is applied from 20 days before sowing to immediately before sowing, more preferably from 10 days before sowing to immediately before sowing.
  • the compound X and the compound Y are sequentially applied to the field of the crop, when the compound X is applied after sowing of the crop seeds, the compound X is usually applied immediately after sowing to before flowering. More preferably, it is between immediately after sowing and before emergence and between the true leaves 1 to 6 of the crop.
  • the compound Y is usually applied immediately after sowing to before flowering. More preferably, it is between immediately after sowing and before emergence and between the true leaves 1 to 6 of the crop.
  • the compound X and the compound Y are sequentially applied to a crop field
  • the case where the compound X is applied simultaneously with the sowing of the crop seeds is a case where the seeding machine and the spraying machine are integrated.
  • the case where the compound Y is applied simultaneously with the sowing of the crop seeds is a case where the seeding machine and the spraying machine are integrated.
  • the preparation containing the compound X and the compound Y as the active ingredients can be diluted with water and used. Further, a preparation containing compound X as an active ingredient and a preparation containing compound Y as an active ingredient may be used as a mixture. Further, a preparation containing compound X and compound Y as active ingredients and a preparation containing another herbicide as active ingredients may be mixed and used.
  • Urticaceae Urtica urens Polygonaceae: Polygonum convolvulus, Polygonum lapathifolium, Polygonum pensylvanicum, Polygonum persicrum, Polygonum arenaum Polygonum longetum, Polygonum areicular, Polygonum avicular.
  • Legume weeds (Fabaceae): Aeschynomene indica, Aeschynomene rudis, Sesbania exaltata, Cassia obtusifolia, Cassia occidentalis, Juzuhagi (Desmo).
  • Oxalidaceae Oxalis corniculata, Oxalis stricta, Oxalis oxyptera Weeds (Geraniaceae): American Furo (Geranium carolinense), Dutch Furo (Erodium cicutarium) Euphorbiaceae (Euphorbiaceae): Euphorbia helioscopia, Euphorbia maculata, Euphorbia humistrata, Euphorbiasilupa, Euphorbia silupe, Euphorbia heliosopia (Acalypha australis), tropic croton (C
  • Malvaceae Malvaceae: Abutilon theophrasti, Sida rhombifolia, Malva Sida, Sida cordifolia, Sida spinosa, Sida glaziovii, Sida santaremnensis ), ginseng (Hibiscus trionum), mallow (Anoda cristata), enoki mallow (Malvastrum coromandelianum)
  • Weeds (Sterculiaceae): Walnutia indica Weeds (Violaceae): Makibasuremu (Viola arvensis), Wild Pansies (Viola tricolor) Cucurbitaceae: Arechiuri (Sicyos angulatus), Wild Cucumber (Echinocystis lobata), Wild bitter gourd (Momordica charantia) Lythraceae: Lythraceae: Ammannia multiflora, Ammannia auriculata, Amoenia coccinea, Lythrum salicaria, Rotala indica Echinaceae weeds (Elatinaceae): Mizojabe (Elatine triandra), California water wort (Elatine californica)
  • Apiaceae Seri (Oenanthe javanica), Nora carrot (Daucus carota), Dokunindo (Conium maculatum) Araliaceae: Hydrocotyle sibthorpioides, Brazilian Codweed (Hydrocotyle ranunculoides) Pinus weed (Ceratophyllaceae): Matsumo (Ceratophyllum demersum) Weeds (Cabombaceae): Carrots (Cabomba caroliniana) Alifactaceae weeds (Haloragaceae): Greater ducks (Myriophyllum aquaticum), Fusamo (Myriophyllum verticillatum), Water mill foils (Myriophyllum spicatum, Myriophyllum heterophyllum, etc.) Sapindaceae: Cardiospermum halicacabum Primulaceae: Primulaceae: Anagallis arvensis Weeds (Asclep
  • Convolvulaceae Weeds Morning glory (Ipomoea nil), American morning glory (Ipomoea hederacea), Malva morning glory (Ipomoea purpurea), Malba american morning glory (Ipomoea hederacea var.
  • Solanaceae Solanaceae (Datura stramonium), physalis physalis (Solanum nigrum), Terimino physalis (Solanum americanum), American physalis (Solanum ptycanthum), Quercus sycamore (Solanum sarrachoides), tomato numbe , King ginkgo biloba (Solanum aculeatissimum), wild tomato (Solanum sisymbriifolium), warnabis (Solanum carolinense), physalis physalis (Physalis angulata), smooth ground cherry (Physalis subglabrata), oxenali (Nicandra physalodes) Weeds (Scrophulariaceae): Veronica hederaefolia, Veronica persica, Veronica arvensis, Lindernia procumbens, Lindernia dubia, Azusa angustifolia
  • Plantago weeds Plantainaceae: plantain (Plantago asiatica), plantain lanceolata (Plantago lanceolata), plantain (Plantago major), Mizuhakobe (Callitriche palustris)
  • Weeds (Asteraceae): Orchards (Xanthium pensylvanicum), Giants (Xanthium occidentale), Igaronas (Xanthium italicum), Wild sunflowers (Helianthus annuus), Gold chalice (Matricaria chamomper), Matricaria, Matricaria, Matricaria ), orchard (Matricaria matricarioides), mugwort (Artemisia princeps), mugwort (Artemisia vulgaris), Chinese magwort (Artemisia verlotorum), stilts (Solidago altissia), Gadva (Taraxac) (Galinsoga parviflora), Nobologiku (Senecio vulgaris), Senecio brasiliensis, Senecio gresebachi, Conyza bonariensis (Conyza cana cygana cygana cygana sisana), Conyza cygan
  • Cyperaceae Weeds (Cyperaceae): Cyperus microiria, Kogomegayatsuya (Cyperus iria), Kugayatsuya (Cyperus cyperus difformis), Cyperus glaze (Cyperus cyperus flacidus) (Cyperus odoratus), Cyperus serotinus, Cyperus rotundus, Cyperus esculentus, Himekug (Kyllinga gracillima), Elidag (Kyllinga brevifolia), Hiderico (Fimbristylis) acicularis), kuroguwai (Eleocharis kuroguwai), firefly (Schoenoplectiella hotarui), inuhotarui (Schoenoplectiella juncoides), taiwan yamai (Schoenoplectiella wallichii), hime kangarei
  • weeds variation within species is not particularly limited. That is, those having reduced sensitivity (also referred to as resistance) to a specific herbicide are also included.
  • the decrease in susceptibility may be due to a mutation at the target site (point of action mutation) or a factor other than point of action mutation (non-point of action mutation).
  • Point-of-action mutations are those in which amino acid substitutions have occurred in the protein that is the target site due to mutations in the nucleic acid sequence portion (open reading frame) corresponding to the amino acid sequence of the protein, as well as deletion of the suppressor sequence in the promoter region and enhancement of the enhancer sequence. Including those in which the protein at the target site is overexpressed due to amplification or mutation such as increase in gene copy number.
  • Factors of decreased sensitivity due to non-acting point mutation include metabolic enhancement, absorption failure, migration failure, and excretion from the system.
  • factors that enhance metabolism include increased activity of metabolic enzymes such as cytochrome P450 monooxygenase, arylacylamidase, esterase, and glutathione S transferase.
  • Excretion outside the system includes transport to the vacuole by the ABC transporter.
  • Glyphosate resistance As an example of a decrease in susceptibility of weeds due to a mutation of a point of action, there is a weed having a mutation that causes any of the following amino acid substitutions or a plurality of amino acid substitutions in the EPSPS gene.
  • Thr102Ile, Pro106Ser, Pro106Ala, Pro106Leu, Pro106Thr Particularly, those having both Thr102Ile and Pro106Ser, and those having both Thr102Ile and Pro106Thr are mentioned.
  • Glyphosate-resistant Ohishiba, musculus barley, rye barley, barley, Bidens subalternans and the like having these action point mutations are effectively controlled.
  • glyphosate resistance due to a point of action mutation there is an increase in the copy number of the EPSPS gene (PNAS, 2018 115 (13) 3332-3337).
  • glyphosate-resistant giant blue squirrels, water hemp, hogwort and the like having an increased EPSPS gene copy number are effectively controlled.
  • Examples of decreased weed susceptibility due to non-acting point mutations include glyphosate-resistant Dioscorea japonicum, Pleurotus cornucopiae, and Pleurotus cornucopiae, which are involved in the ABC transporter, and these are effectively controlled by the present invention.
  • the expression of aldoketo reductase is increased, and the soybean fly is known to have reduced sensitivity to glyphosate (Plant Physiology 181, 1519-1534), but the present invention effectively controls it.
  • ALS-inhibiting herbicide resistance As an example of the decrease in the sensitivity of weeds due to the mutation of the point of action, weeds having mutations causing any of the following or multiple amino acid substitutions in the ALS gene can be mentioned. Ala122Thr, Ala122Val, Ala122Tyr, Pro197Ser, Pro197His, Pro197Thr, Pro197Arg, Pro197Leu, Pro197Gln, Pro197Ala, Pro197Ile, Ala205Val, Ala205Phe, Asp376Glu, Asp376Glu, Asp376Glu, Asp376Geu, Asp376Grp, Asp376Ger, Asp376Ger, Asp376Gru, Asp376Ger, Asp376Gr, Asp376Gr, Asp376Ger, Asp376Ger, Asp376Ger, Asp376Ger, Asp376Ger, Asp376Ger, Asp376Ger, As
  • An example of a reduction in the sensitivity of weeds due to a non-acting point mutation is a weed that has become resistant to an ALS inhibitor due to CYP or GST, and the present invention effectively controls these.
  • a weed that has become resistant to an ALS inhibitor due to CYP or GST
  • the present invention effectively controls these.
  • corn borer overexpressed with CYP81A10 and CYP81A1v1 Tainubie overexpressed with CYP81A12 and CYP81A21
  • ACCase inhibitor resistance As an example of a decrease in susceptibility of weeds due to a point of action mutation, weeds having mutations causing any of the following or multiple amino acid substitutions in the ACCase gene can be mentioned.
  • ACCase resistant weeds having these action point mutations are effectively controlled.
  • An example of a reduction in the sensitivity of weeds due to a non-acting point mutation is a weed that has become resistant to an ACCase inhibitor due to CYP or GST, and the present invention effectively controls these.
  • PPO inhibitor resistance Weeds with mutations that cause one or more of the following amino acid substitutions in the PPO gene are examples of reduced susceptibility to weeds due to point-of-effect mutations.These mutations cause resistance to carfentrazone-ethyl, fomesafen and lactofen. Known as a sex mutation or predicted to be a resistance mutation.
  • the PPO gene of weeds has a PPO1 gene and a PPO2 gene, but the mutation may be in either the PPO1 gene, the PPO2 gene, or both.
  • Preferred is a case where the PPO2 gene has a mutation.
  • Arg128Met means that the 128th amino acid has a mutation.
  • the mutation corresponds to the 98th position (Weed Science 60, 335-344), and the notation Arg98Leu is known. This Arg98 is synonymous with Arg128 in the present specification.
  • Arg128Met and Arg128Gly are known in P.
  • the present invention effectively controls PPO inhibitor-resistant weeds having these action point mutations, but the PPO inhibitor-resistant weeds to be controlled are not limited thereto. That is, PPO1 or PPO2 in Arg128Leu, Arg128Met, Arg128Gly, Arg128His, Arg128Ala, Arg128Cys, Arg128Glu, Arg128Ile, Arg128Lys, Arg128Asn, Arg128Gln, Arg128G11, ArG128Gly, Arg128Thr, Arg128Gly, Arg128Gly, Arg128Clu , Ser149Ile or Gly399Ala having a mutation, but also water hemp having the mutation, ragweed having the mutation, and Drosophila melanogaster having the mutation are effectively controlled.
  • non-action point mutations dicamba-resistant honaga aogeitou, which is suggested to involve CYP, and 2,4-D-resistant water hemp are known, and the present invention effectively controls these.
  • HPPD inhibitor resistance Examples of the reduction in susceptibility of weeds due to non-action point mutation include water hemp and blue dragonfly which have become resistant to HPPD inhibitors due to involvement of CYP or GST. Controlled. As an example of them, it is known that the blue-toothed dragonfly overexpressed CYP72A219, CYP81B and CYP81E8.
  • Photosystem II inhibitor resistance An example of a reduction in susceptibility of weeds due to a point-of-action mutation is a weed having a mutation that causes one or more of the following amino acid substitutions in the psbA gene. Val219Ile, Ser264Gly, Ser264Ala, Phe274Val. INDUSTRIAL APPLICABILITY According to the present invention, the photochemical system II inhibitor-resistant giant dragonfly and water hemp having these action point mutations are effectively controlled. Examples of reduced sensitivity of weeds due to non-acting point mutations include CYP, GST, or AAA-related photochemical system II inhibitor-resistant plants such as Helicoverpa armigera and water hemp. Are effectively controlled.
  • CYP71R4 overexpressed Bomugi is known.
  • Resistance to glutamate synthase inhibitors An example of a decrease in susceptibility of weeds due to a mutation of the action point is a weed having a mutation that causes an amino acid substitution of Asp171Asn in the glutamine synthetase gene.
  • INDUSTRIAL APPLICABILITY According to the present invention, glutamine synthase inhibitor-resistant giant dragonfly, water hemp, and the like having this mutation are effectively controlled. Examples of reduced susceptibility of weeds due to non-acting point mutations include glutinosanate resistance and water hemp, which are involved in CYP or GST, but are effectively controlled by the present invention. ..
  • the blue-toothed dragonfly overexpressed CYP72A219, CYP81B and CYP81E8 Resistant weeds, two or more groups of the above groups (2 groups arbitrarily selected, 3 groups arbitrarily selected, 4 groups arbitrarily selected, 5 groups arbitrarily selected, 6 groups arbitrarily selected , 7 groups, 8 groups) can be effectively controlled even if they are resistant weeds (stacked) that also have resistance to (7 groups, 8 groups).
  • Water hemp resistant to all photosystem II inhibitors, HPPD inhibitors, 2,4-D, PPO inhibitors, ALS inhibitors and glyphosate are known as effective examples of stacked resistant weeds, but they are also effective.
  • the stack may be a combination of action point mutations, a combination of non-action point mutations, or a combination of action mutations and non-action point mutations.
  • Examples of the herbicides that may be contained in the composition of the present invention in addition to the compound X and the compound Y include the followings. These can also be used in admixture with the composition of the present invention containing only compound X and compound Y as active ingredients.
  • Herbicide glyphosate and its salt (isopropylammonium salt, ammonium salt, potassium salt, guanidine salt, dimethylamine salt, monoethanolamine salt, choline salt, BAPMA (N,N-bis-(aminopropyl)methylamine) ) Salt, 2,4-D and its salt or ester (ammonium salt, butyl ester, 2-butoxypropyl ester, butyl ester, diethylammonium salt, dimethylammonium salt, diolamine salt, dodecylammonium salt, ethyl ester, 2) -Ethylhexyl ester, heptyl ammonium salt, isobutyl ester, isooctyl ester, isopropyl ester, isopropyl ammonium salt, lithium salt, meptyl ester, methyl ester, octyl ester, pentyl ester, propyl ester, sodium salt,
  • Salt or ester (butyl ester, triethylammonium salt), fluroxypyr (fluroxypyr), fluroxypyrmeptyl (fluroxypyr-meptyl), thiazopyr (thiazopyr), aminopyralide (aminopyralid) and its salts (potassium salt, triisopropanolammonium salt).
  • Imazapyr imazapyr-ammonium, imazaquin, imazaquin-ammonium, imazethapyr ammonium, imazethapyr-imazapyr, imazethapyr-imazapyr, imazethapyr, imazethapyr, imazethapyr clodinafop), clodinafop propargyl (clodinafop-propargyl), cyhalofop (cyhalofop), cyhalofop butyl (cyhalofop-butyl), diclofop (as diclofop), diclofop-methyl (diclofop-methyl), fenoxaprop (fenoxaprop), phenoxy Fenoxaprop-Ethyl, Fenoxaprop-P, Fenoxaprop-P-Ethyl, Fluazifop, Fluazifop-Flu-Butyl fluazifop, Fluazifo
  • Flumiclorac-pentyl fomesafen-sodium, lactofen, saflufenacil, thiaphenacyl, tiafenacil, trifludimoxazine sodium trifludiz (Acifluorfen-sodium), aclonifen (aclonifen), bifenox (bifenox), clomethoxyphene (chlomethoxyphen), chloronitrophen (chlornitrofen), ethoxyphenethyl (ethoxyphen-ethyl), fluorodifen (fluodifen).
  • glyphosate potassium salt glyphosate guanidine salt, glyphosate dimethylamine salt, glyphosate monoethanolamine salt, glufosinate ammonium salt, glyphosate isopropylammonium salt, 2, 4-D choline salt, pyroxasulfone, dicamba diglycolamine salt, dicamba BAPMA salt, dicamba TBA salt, dicamba TBP salt, flumioxazin, flumicrolacpentyl, crethodim, lactofen, S metolachlor, metribuzin, flufenacet, Preferred are nicosulfuron, rimsulfuron, acetochlor, mesotrione, isoxaflutol, chlorimuron ethyl, thifensulfuron methyl, chloranthrum methyl, and imazethapyr
  • a herbicide Z examples of combinations with a herbicide which may be used in combination with the compound X and the compound Y (hereinafter sometimes referred to as a herbicide Z) are listed below, but the invention is not limited thereto.
  • the ratio of the herbicide Z to the compound X is usually 0.01 to 1000 times by weight, and preferably 0.1 to 300 times by weight.
  • composition of the present invention More preferable specific combinations for using the composition of the present invention and one or more herbicides are the composition of the present invention + glyphosate potassium salt, and the composition of the present invention + glyphosate monoethanolamine salt.
  • composition of the present invention containing dicamba diglycolamine salt, the composition of the present invention + dicamba BAPMA salt, the composition of the present invention + Dicamba TBA salt, and the composition of the present invention + dicamba TBP salt.
  • composition of the present invention More preferable specific combinations for using the composition of the present invention and one or more herbicides are the composition of the present invention + glyphosate potassium salt + dicambadiglycolamine salt, the composition of the present invention + glyphosate potassium salt + dicamba.
  • composition of the present invention More preferred specific combinations for using the composition of the present invention together with one or more herbicides are the composition of the present invention+glyphosate monoethanolamine salt+dicambadiglycolamine salt, the composition of the present invention+glyphosate monoethanol.
  • Amine salt+dicamba BAPMA salt composition of the present invention+glyphosate monoethanolamine salt+dicamba TBA salt, and composition of the present invention+glyphosate monoethanolamine salt+dicamba TBP salt.
  • phytonutrientological management in general agricultural crop cultivation can be performed.
  • the fertilizer application system may be based on Precision Agriculture, or may be uniform in practice.
  • nitrogen-fixing bacteria and mycorrhizal fungi can be used together with seed treatment for inoculation.
  • Example 1 Sowing plastic pots filled with soil are seeded with weeds (Euphoria japonicus, Spodoptera litura, Rhizopus communis, Ragweed, Obu taxa, Scutellaria barbata, Shiroza, Houkigi, Inobie and Akinoenokurokosa).
  • weeds Euphoria japonicus, Spodoptera litura, Rhizopus communis, Ragweed, Obu taxa, Scutellaria barbata, Shiroza, Houkigi, Inobie and Akinoenokurokosa
  • 20 g/ha of compound X+25, 50, 100, or 200 g/ha of compound Y1 is treated on the soil surface with a spray water volume of 200 L/ha. After that, it is cultivated in a greenhouse, soybeans are sown 7 days later, and 14 days later, the herbicidal effect on weeds and phytotoxicity to soybeans are investigated. A synergistic weed control effect is confirmed as compared to the
  • Sow weeds (Ohgonagaoagatoto, Hosobinubiyu, Ragweed, Insectidae, Aquinoe foxtail) and soybean are sown in plastic pots filled with soil.
  • 80 g/ha of compound X+25, 50, 100, or 200 g/ha of compound Y1 is treated on the soil surface with a spray water volume of 200 L/ha. After that, it is cultivated in a greenhouse, and 21 days later, the effect on weeds and the phytotoxicity on soybean are investigated.
  • a synergistic weed control effect is confirmed as compared to the single use of each compound.
  • Example 3 Seed weeds (Scottish pearl moth, Amaranthus communis, P. persicae, Rhododendron, Ragweed, Stinkweed, Scutellaria barbata, Spodoptera chinensis, Shiroza, Houkigi, Inobie and Akinoenokurokosa) and soybeans are sowed in plastic pots filled with soil. Then, the plant is cultivated in a greenhouse, and 21 days after sowing, 20 g/ha of compound X+25, 50, 100, or 200 g/ha of compound Y1 is treated with foliage at a spraying water amount of 200 L/ha. Furthermore, the plant is cultivated in a greenhouse, and 14 days after the treatment, its effect on weeds and phytotoxicity to soybean are investigated. A synergistic weed control effect is confirmed as compared to the single use of each compound.
  • Example 4-6 In the treatment of Example 1-3, Roundup WeatherMax (660 g/L glyphosate potassium salt, manufactured by Monsanto) was applied to the spray solution containing the compound X and the compound Y1 at a treatment rate of 2.338 L/ha (32 fluid ounces/acre). In the same manner as above.
  • Roundup WeatherMax 660 g/L glyphosate potassium salt, manufactured by Monsanto
  • Example 7-9 In the treatment of Example 4-6, XtendiMax (dicambadiglycolamine salt, dicambaic acid 350 g/L, manufactured by Monsanto) was applied to the spray liquid containing compound X and compound Y1 at a treatment amount of 1607 ml/ha (22 liquid volume). Ounce/acre) and do the same.
  • XtendiMax dicambadiglycolamine salt, dicambaic acid 350 g/L, manufactured by Monsanto
  • Example 10-12 In the treatment of Example 1-3, Roundup Extend (glyphosate monoethanolamine 240 g/L+dicamba diglycolamine 120 g/L, manufactured by Monsanto) was applied to a spray solution containing compound X and compound Y1 at a treatment amount of 4.677 L/ha ( 64 fl oz/acre) and the same procedure.
  • Roundup Extend glyphosate monoethanolamine 240 g/L+dicamba diglycolamine 120 g/L, manufactured by Monsanto
  • Examples 13-24 The soybeans of Examples 1-12 are replaced by corn or cotton, and the same procedure is performed.
  • Example 25 NipsIt (600 g/L clothianidin, manufactured by Valent) is treated soybean (cultivar Genuity Roundup Ready2Yield soybean) seeds so that the NipsIt treatment amount is 206 mL/kg seeds (1.28 fl oz/100 lb seeds).
  • Formulation containing compound X (5 parts by weight of compound X, 2 parts by weight of Geronol FF/4-E (manufactured by Rhodia), 8 parts by weight of Geronol FF/6-E (manufactured by Rhodia), Solvesso 200 (manufactured by Exxon Mobile) )
  • An emulsion obtained by thoroughly mixing 85 parts by weight (hereinafter referred to as preparation X)) and a preparation containing compound Y1 (hereinafter referred to as preparation Y1) are mixed with water to give a treated amount of compound Y1 of 25,
  • preparation Y1 a preparation containing compound Y1
  • Example 26 Soybean seeds are treated with NipsIt as in Example 25.
  • the treatment amount of the compound X was 5, 20 or 80 g/ha
  • the treatment amount of the compound Y1 was 25, 50, 100 or 200 g/ha
  • Roundup WeatherMax glyphosate potassium salt 660 g/L, Monsanto company
  • Preparation X) the preparation X, the preparation Y1, and the RoundupWeatherMax are treated so that the treated amount of the product is 2.338 L/ha (32 fl oz/acre), and the soybean is sown in the field after 7 days.
  • Roundup WeatherMax (glyphosate potassium salt 660 g/L, manufactured by Monsanto) is applied to the field in the third leaf stage of soybean so that the treatment amount is 2.338 L/ha (32 fl oz/acre).
  • Example 27 Soybean seeds are treated with NipsIt as in Example 25 and sown in the field. On the day after seeding, the preparation X and the preparation Y1 are treated in the field so that the treatment amount of the compound X is 5, 20 or 80 g/ha and the treatment amount of the compound Y1 is 25, 50, 100 or 200 g/ha.
  • Roundup WeatherMax glyphosate potassium salt 660 g/L, manufactured by Monsanto
  • the treatment amount is 2.338 L/ha (32 fl oz/acre).
  • Example 28 Soybean seeds are treated with NipsIt as in Example 25 and sown in the field.
  • the treatment amount of compound X was 5, 20 or 80 g/ha
  • the treatment amount of compound Y was 25, 50, 100 or 200 g/ha
  • the treatment amount of Roundup WeatherMax (glyphosate potassium salt 660 g/L, manufactured by Monsanto).
  • Formulation X, Formulation Y1 and RoundupWeatherMax are applied to the field so that the amount is 2.338 L/ha (32 fl oz/acre).
  • Roundup WeatherMax (glyphosate potassium salt 660 g/L, manufactured by Monsanto) is applied to the field in the third leaf stage of soybean so that the treatment amount is 2.338 L/ha (32 fl oz/acre).
  • Examples 29 to 32 In each of Examples 25 to 28, when the Roundup WeatherMax was treated on the day after sowing or at the soybean true leaf 3 leaf stage, the treatment amount of XtendiMax (dicamba diglycolamine salt, 350 g/L as dicamba acid, manufactured by Monsanto) was 1607 ml. /Ha (22 fl oz/acre) in addition to Roundup WeatherMax.
  • XtendiMax dicamba diglycolamine salt, 350 g/L as dicamba acid, manufactured by Monsanto
  • Examples 33-36 In each of Examples 25 to 28, when RoundupWeatherMax was treated on the day after seeding or at the soybean true leaf 3 leaf stage, instead of treating RoundupWeatherMax, Roundup Extension (glyphosate monoethanolamine 240 g/L+dicamba diglycolamine 120 g/L, Monc 120 mg/L, dicanvas diglycolamine 120 g/L, Mon. (Manufactured by the same company) is used so that the amount of Roundup Extend to be treated is 4.677 L/ha (64 fl oz/acre).
  • Roundup Extension glyphosate monoethanolamine 240 g/L+dicamba diglycolamine 120 g/L, Monc 120 mg/L, dicanvas diglycolamine 120 g/L, Mon. (Manufactured by the same company) is used so that the amount of Roundup Extend to be treated is 4.677 L/ha (64 fl oz/acre).
  • Examples 37-48 In each of Examples 25 to 36, INOVATE (clothianidin 160 g/L+metalaxyl 13 g/L+ipconazole 8 g/L, manufactured by Valent) was used instead of NipsIt, and the treatment amount of INOVATE was 309 mL/100 kg seed (4.74 liquid). Ounce/100 pounds seed).
  • Examples 49-60 In each of Examples 25 to 36, CruiserMAXX Vibrance (thiamethoxam 240 g/L+metalaxyl M36 g/L+fludioxonil 12 g/L+sedaxane 12 g/L, manufactured by Syngenta) was used instead of NipsIt, and CruiserMAXX Vibrance amount of 100 mL/2 kg was used. Treat to seed (3.22 fl oz/100 lb seed).
  • Examples 61-72 In each of Examples 25-36, instead of treating the soybean seeds with NipsIt, the Acceleron system (DX-612 (fluxapyroxad 326 g/L, Monsanto) 31 ml/100 kg seed + DX-309 (metalaxyl 313 g/L) was used.
  • DX-612 fluxapyroxad 326 g/L, Monsanto
  • DX-309 metalaxyl 313 g/L
  • Monsanto 242 ml/100 kg seeds (1.5 fl oz/100 lb seed) + DX-109 (Pyraclostrobin 200 g/l, Monsanto) 242 ml/100 kg seeds (1.5 fl oz/100 lb) Seeds)+IX-104 (imidacloprid 600 g/L, Monsanto) 515 ml/100 kg seeds (3.2 fl oz/100 lb seeds)).
  • Examples 73 to 120 In each of Examples 25 to 72, corn seeds or cotton seeds are used instead of soybean seeds.
  • Examples 121-216 In Examples 25-120, the crop is changed to a crop having the Roundup Ready 2 Xtend trait, and the same procedure is performed.
  • Examples 217-312 In Examples 25-120, this crop is transformed into a crop having the Roundup Ready 2 Xtend trait and the PPO inhibitor resistance trait, and the same procedure is performed.
  • Examples 313-408 In Examples 25-120, the crops are changed to crops having the Roundup Ready 2 Xtend trait, the PPO inhibitor resistance trait, and the HPPD inhibitor resistance trait, and the same operation is performed.
  • Example 409-816 Example 1-408 is carried out by substituting the compound Y2 for the compound Y1 or the compound Y3.
  • Weeds can be effectively controlled by the herbicidal composition of the present invention.

Abstract

L'invention concerne une composition herbicide qui présente un effet supérieur de lutte contre les mauvaises herbes. L'invention concerne plus particulièrement une composition herbicide comprenant de l'éthyl[3-[2-chloro-4-fluoro-5-(1-méthyl-6-trifluorométhyl-2,4-dioxo-1,2,3,4-tétrahydropyrimidine-3-yl) phénoxy]-2-pyridyloxy] acétate et au moins un composé choisi dans le groupe de composés Y. Groupe de composés Y: le groupe est constitué de 2-chloro-N- (1-méthyl -1H-tétrazole-5-yl)-3-(méthylthio)-4-(trufluorométhyl) benzamide, 2-méthyl-N-(5-méthyl1,3,4-oxadiazole-2-yl)-3-(méthanesulfonyl)-4-(trifluorométhyl)benzamide et 4-(4-fluorophényl)-6-[(2-hydroxy-6-oxo-1-cyclohexène-1-yl) carbonyl]-2-méthyl-1,2,4-triazine-3,5 (2H,4H) dione.
PCT/JP2020/004518 2019-02-13 2020-02-06 Composition herbicide et procédé de lutte contre les mauvaises herbes WO2020166477A1 (fr)

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Cited By (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20220167622A1 (en) * 2020-12-02 2022-06-02 Valent U.S.A. Llc Aqueous composition of epyrifenacil, mesotrione and pyroxasulfone
US20220167621A1 (en) * 2020-12-02 2022-06-02 Valent U.S.A. Llc Aqueous composition of epyrifenacil, flumioxazin and pyroxasulfone
WO2022138632A1 (fr) * 2020-12-24 2022-06-30 住友化学株式会社 Composition herbicide et procédé de lutte contre les mauvaises herbes

Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2008522965A (ja) * 2004-12-06 2008-07-03 シンジェンタ パーティシペーションズ アクチェンゲゼルシャフト 除草性組成物
WO2013080484A1 (fr) * 2011-11-30 2013-06-06 クミアイ化学工業株式会社 Composition d'herbicide
JP2014510088A (ja) * 2011-03-22 2014-04-24 バイエル・インテレクチユアル・プロパテイー・ゲー・エム・ベー・ハー Ｎ−（１，３，４−オキサジアゾール−２−イル）アリールカルボキサミドおよび除草剤としてのその使用
JP2016538300A (ja) * 2013-11-28 2016-12-08 バイエル・クロップサイエンス・アクチェンゲゼルシャフト Ｈｐｐｄ阻害薬型除草剤に対して耐性であるトランスジェニック作物の区域で望ましくない植物を防除するための２−クロロ−３−（メチルスルファニル）−ｎ−（１−メチル−１ｈ−テトラゾール−５−イル）−４−（トリフルオロメチル）ベンズアミド又はそれの塩の使用

Patent Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2008522965A (ja) * 2004-12-06 2008-07-03 シンジェンタ パーティシペーションズ アクチェンゲゼルシャフト 除草性組成物
JP2014510088A (ja) * 2011-03-22 2014-04-24 バイエル・インテレクチユアル・プロパテイー・ゲー・エム・ベー・ハー Ｎ−（１，３，４−オキサジアゾール−２−イル）アリールカルボキサミドおよび除草剤としてのその使用
WO2013080484A1 (fr) * 2011-11-30 2013-06-06 クミアイ化学工業株式会社 Composition d'herbicide
JP2016538300A (ja) * 2013-11-28 2016-12-08 バイエル・クロップサイエンス・アクチェンゲゼルシャフト Ｈｐｐｄ阻害薬型除草剤に対して耐性であるトランスジェニック作物の区域で望ましくない植物を防除するための２−クロロ−３−（メチルスルファニル）−ｎ−（１−メチル−１ｈ−テトラゾール−５−イル）−４−（トリフルオロメチル）ベンズアミド又はそれの塩の使用

Cited By (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20220167622A1 (en) * 2020-12-02 2022-06-02 Valent U.S.A. Llc Aqueous composition of epyrifenacil, mesotrione and pyroxasulfone
US20220167621A1 (en) * 2020-12-02 2022-06-02 Valent U.S.A. Llc Aqueous composition of epyrifenacil, flumioxazin and pyroxasulfone
WO2022119799A3 (fr) * 2020-12-02 2022-08-25 Valent U.S.A. Llc Composition aqueuse d'épyrifénacil, de mésotrione et de pyroxasulfone
WO2022119797A3 (fr) * 2020-12-02 2022-10-27 Valent U.S.A. Llc Composition aqueuse d'épyrifénacil, de flumioxazine et de pyroxasulfone
WO2022138632A1 (fr) * 2020-12-24 2022-06-30 住友化学株式会社 Composition herbicide et procédé de lutte contre les mauvaises herbes

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