Classifications

• • A—HUMAN NECESSITIES
  • A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
  • A01M—CATCHING, TRAPPING OR SCARING OF ANIMALS; APPARATUS FOR THE DESTRUCTION OF NOXIOUS ANIMALS OR NOXIOUS PLANTS
  • A01M29/00—Scaring or repelling devices, e.g. bird-scaring apparatus
  • A01M29/12—Scaring or repelling devices, e.g. bird-scaring apparatus using odoriferous substances, e.g. aromas, pheromones or chemical agents
• • A—HUMAN NECESSITIES
  • A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
  • A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
  • A01N25/00—Biocides, pest repellants or attractants, or plant growth regulators, characterised by their forms, or by their non-active ingredients or by their methods of application, e.g. seed treatment or sequential application; Substances for reducing the noxious effect of the active ingredients to organisms other than pests
  • A01N25/02—Biocides, pest repellants or attractants, or plant growth regulators, characterised by their forms, or by their non-active ingredients or by their methods of application, e.g. seed treatment or sequential application; Substances for reducing the noxious effect of the active ingredients to organisms other than pests containing liquids as carriers, diluents or solvents
• • A—HUMAN NECESSITIES
  • A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
  • A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
  • A01N25/00—Biocides, pest repellants or attractants, or plant growth regulators, characterised by their forms, or by their non-active ingredients or by their methods of application, e.g. seed treatment or sequential application; Substances for reducing the noxious effect of the active ingredients to organisms other than pests
  • A01N25/02—Biocides, pest repellants or attractants, or plant growth regulators, characterised by their forms, or by their non-active ingredients or by their methods of application, e.g. seed treatment or sequential application; Substances for reducing the noxious effect of the active ingredients to organisms other than pests containing liquids as carriers, diluents or solvents
  • A01N25/04—Dispersions, emulsions, suspoemulsions, suspension concentrates or gels
• • A—HUMAN NECESSITIES
  • A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
  • A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
  • A01N27/00—Biocides, pest repellants or attractants, or plant growth regulators containing hydrocarbons
• • A—HUMAN NECESSITIES
  • A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
  • A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
  • A01N31/00—Biocides, pest repellants or attractants, or plant growth regulators containing organic oxygen or sulfur compounds
  • A01N31/02—Acyclic compounds
• • A—HUMAN NECESSITIES
  • A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
  • A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
  • A01N37/00—Biocides, pest repellants or attractants, or plant growth regulators containing organic compounds containing a carbon atom having three bonds to hetero atoms with at the most two bonds to halogen, e.g. carboxylic acids
  • A01N37/02—Saturated carboxylic acids or thio analogues thereof; Derivatives thereof
• • A—HUMAN NECESSITIES
  • A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
  • A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
  • A01N61/00—Biocides, pest repellants or attractants, or plant growth regulators containing substances of unknown or undetermined composition, e.g. substances characterised only by the mode of action
• • A—HUMAN NECESSITIES
  • A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
  • A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
  • A01N65/00—Biocides, pest repellants or attractants, or plant growth regulators containing material from algae, lichens, bryophyta, multi-cellular fungi or plants, or extracts thereof
  • A01N65/08—Magnoliopsida [dicotyledons]
  • A01N65/22—Lamiaceae or Labiatae [Mint family], e.g. thyme, rosemary, skullcap, selfheal, lavender, perilla, pennyroyal, peppermint or spearmint
• • A—HUMAN NECESSITIES
  • A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
  • A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
  • A01N65/00—Biocides, pest repellants or attractants, or plant growth regulators containing material from algae, lichens, bryophyta, multi-cellular fungi or plants, or extracts thereof
  • A01N65/08—Magnoliopsida [dicotyledons]
  • A01N65/28—Myrtaceae [Myrtle family], e.g. teatree or clove
• • A—HUMAN NECESSITIES
  • A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
  • A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
  • A01N65/00—Biocides, pest repellants or attractants, or plant growth regulators containing material from algae, lichens, bryophyta, multi-cellular fungi or plants, or extracts thereof
  • A01N65/40—Liliopsida [monocotyledons]
  • A01N65/44—Poaceae or Gramineae [Grass family], e.g. bamboo, lemon grass or citronella grass
• • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
  • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
  • Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
  • Y02A50/00—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
  • Y02A50/30—Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change

Definitions

• the present invention relates to a pest repellent composition.
• Pests for example, flying pests such as mosquitoes and flies are factors that cause pathogens in animals such as humans to cause infectious diseases and dermatitis.
• some mosquitoes are pathogens such as dengue fever, zika fever, yellow fever, encephalitis, and malaria, and are hygienically extremely harmful insects.
• a method of spraying an insecticide or applying a repellent to the skin surface has been widely used.
• DEET N,N-diethyl
• Toluamide is commonly used.
• Pests such as mosquitoes have chemoreceptive systems such as thermoreceptors that sense the body temperature of animals, olfactory receptors that sense volatile substances such as body odor, and carbon dioxide receptors that sense carbon dioxide.
• Animal detection is performed by DEET, which repels pests by modulating the chemoreceptive system of such pests to neutralize the cognitive sensation of the pests.
• DEET has an unpleasant odor, and in order to exert a sufficient repellent sustaining effect, it is necessary to blend a certain amount or more.
• some people cause allergies and rough skin, and there is a problem that the amount of use and the number of times of use are limited for infants and people with sensitive skin.
• Natural essential oils such as citronella oil, lemon eucalyptus oil, lemongrass oil, orange oil, and cassia oil are also used for candles and aroma lotions, and are highly safe for humans.
• the repellent sustaining effect against these pests is not sufficient, and there is a problem in its practicality.
• Patent Document 1 describes that an insect repellent such as DEET is added to a skin protective agent containing a fluorine/polyether co-modified silicone and an ultraviolet protection component.
• Patent Document 2 describes a flying insect repellent that uses natural essential oils such as citronella oil and lemongrass oil and can suppress the arrival of pests and blood-feeding behavior even at low concentrations.
• Patent Document 3 discloses a pest repellent volatilizing composition containing a specific amount of citronellal as a pest repellent component.
• a pest repellent composition or a pest retention control composition containing the following components (A) and (B).
• Inhibitory composition Silicone oil, ester oil, ether oil, hydrocarbon oil, aliphatic alcohol, which has a surface tension of 40 mN/m or less at 25°C and a viscosity of 400 mPa ⁇ s or less at 23°C measured by a B-type rotational viscometer, and One or more non-volatile liquid oily ingredients selected from the group consisting of polyhydric alcohols: 13 mass% or more and 50 mass% or less
• B) 1 selected from the group consisting of citronella oil, lemongrass oil, eucalyptus oil, and narwhal oil At least seed repellent essential oil: 0.005 mass% or more and 15 mass% or less
• C Water: 35 mass% or more and 86.995 mass% or less [5] Contains the following components (A) to (D), and the component (A The mass ratio [(B)/(A)] of the component (B) to () is 0.0001 or more and 0.5 or less, and the mass ratio of
• Inhibitory composition One or more selected from the group consisting of silicone oils, ester oils, and hydrocarbon oils having a surface tension of 40 mN/m or less at 25° C. and a viscosity at 23° C. of not more than 400 mPa ⁇ s by a B type rotational viscometer.
• Non-volatile liquid oily ingredient 13 mass% or more and 50 mass% or less
• B one or more repellent essential oils selected from the group consisting of citronella oil, lemongrass oil, eucalyptus oil, and mint oil: 0.005 mass% or more 15% by mass or less
• C Water: 35% by mass or more and 86.995% by mass or less
• D Thickener: 0.05% by mass or more and 3% by mass or less
• the pest repellent composition and the pest retention control composition of the present invention are compositions containing the following components (A) and (B).
• composition of the present invention contains specific amounts of the components (A) and (B), has an excellent repellent sustaining effect against harmful insects, particularly flying harmful insects, suppresses a strong odor derived from the repellent components, and is suitable for application to the skin. It is a composition.
• the pest repellents those applied to the skin are desired to be safe and have little odor, and to have not only the initial repellent effect but also the durability of the repellent effect.
• the presently available major pest repellents do not currently meet these needs.
• the existing pest repellents such as DEET described in Patent Document 1 have an unpleasant odor and also have a problem in safety to the human body.
• repellents that can be used with more peace of mind.
• the flying insect repellent described in Patent Document 2 and the pest repellent volatilizing composition described in Patent Document 3 exhibit a space repellent effect against harmful insects such as flying insects, and are applied to human skin.
• the pest repellent composition has different preferred dosage forms and required properties.
• An object of the present invention is to provide a pest repellent composition which has excellent repellent sustaining effects against pests, particularly flying pests, is safe, and has a strong odor derived from repellent components suppressed, and is suitable for application to the skin.
• a nonvolatile liquid oily component having a specific surface tension and viscosity has an effect of repelling harmful insects such as mosquitoes, but when actually used on human skin. Had room for further study on the persistence of the repellent effect. Therefore, by combining existing repellent essential oils such as citronella oil with a content such that odor does not pose a problem, and combining with a non-volatile liquid oily component having a specific surface tension and viscosity, a repellent sustaining effect is achieved while suppressing odor. Found to be extended.
• a pest repellent composition containing a non-volatile liquid oily component having a specific surface tension and viscosity and an existing repellent essential oil such as citronella oil in a specific amount can solve the above problems.
• pests, particularly excellent repellent persistence effect against flying pests, safe, and strong odor derived from repellent components is suppressed, pest repellent composition suitable for application to the skin, pest retention control composition, A pest repellent method and a pest retention restraint method can be provided.
• the "repellent effect against pests” means that even if the pests come into contact with an object, they will leave immediately without stopping, and the composition of the present invention corresponds to a contact repellent composition. That is, the pest repellent effect in the present invention is a repellent or insect repellent or pest repellent that repels the target without contacting the target, such as one that does not attract the target to the target, or one that does not approach the target. On the other hand, it has an insecticidal activity and is different from an insecticide that controls pests.
• the composition of the present invention even if the pests such as mosquitoes accrete on the object to which they are applied or adhered, the pests do not stay in place and immediately leave, thereby exhibiting the effect of repelling the pests. is there. Specifically, after a pest such as a mosquito has settled on the skin of an animal such as a human, a retention-suppressing effect of not retaining within a predetermined area of the skin surface for a time sufficient to insert a pricking needle, specifically, for 1 second or more. Have. Such an effect is based on a pest repellent principle which has not existed in the past, and is safe without side effects such as rough skin. Therefore, the composition of the present invention can be used as a pest retention control composition.
• the repellent repellent effect against pests means that the repellent effect is maintained even after a lapse of time after the composition of the present invention is applied to an object.
• the repellent sustaining effect of the present invention especially against flying pests, will be simply referred to as “repellent sustaining effect”.
• the composition of the present invention has a surface tension of 40 mN/m or less at 25° C. as component (A) and a viscosity at 23° C. of 400 mPa ⁇ s or less at 25° C. of (a) silicone oil, (b). It contains one or more non-volatile liquid oily components selected from the group consisting of ester oils, (c) ether oils, (d) hydrocarbon oils, (e) aliphatic alcohols, and (f) polyhydric alcohols.
• the repellent sustaining effect against pests, particularly flying pests is excellent. The reason is not clear, but it is considered as follows.
• flying pests such as mosquitoes have the property of avoiding retention on the wet surface of the limb in order to avoid the attractive force generated from the accretion surface when the limb becomes wet.
• a liquid oily component having a surface tension of 40 mN/m or less at 25°C has high affinity with the limbs of flying pests and has a viscosity of 400 mPa ⁇ s or less.
• the flying pests land on the surface to which the component (A) is applied or adhered, the limbs get wet, and at that time, the attractive force generated from the landing surface is avoided and the landing fly away without stopping at the landing point.
• the term “accretion” in the present invention means that flying insects such as mosquitoes contact an object for a time of less than 1 second. Further, the term “retention” in the present invention means that flying insects such as mosquitoes are kept in contact with the object for 1 second or longer.
• composition of the present invention still has room for improvement from the viewpoint of sufficient repellent sustaining effect in actual use, when the component (A) alone is used. Therefore, in addition to the component (A), a specific amount of the component (B) described later is contained, and the component (B) is applied to the limbs of the flying pest together with the component (A), thereby reducing the odor derived from the component (B).
• the excellent repellent sustaining effect could be realized.
• Non-volatile liquid oil component Non-volatile liquid oil component
• the component (A) contained in the composition of the present invention has a surface tension at 25° C. of 40 mN/m or less and a viscosity at 23° C. measured by a B-type rotational viscometer of 400 mPa ⁇ s or less, (a) silicone oil, ( It is at least one non-volatile liquid oily component selected from the group consisting of b) ester oil, (c) ether oil, (d) hydrocarbon oil, (e) aliphatic alcohol, and (f) polyhydric alcohol.
• the component (A) is preferably liquid at 20° C., more preferably liquid at 15° C., further preferably liquid at 10° C., from the viewpoint of easy application to the skin and improvement of the repellent sustaining effect. Is a non-volatile oil. "Liquid" of the liquid oily component is judged to be liquid in the liquid-solid judgment test according to the American Society for Testing and Materials standard "ASTM D 4359-90: Standard Test Method for Determining Whether a Material is a Liquid or Solid". Means what is done.
• the component (A) is preferably a poorly water-soluble or water-insoluble component from the viewpoint of improving the repellent persistence effect against pests. Specifically, the amount dissolved in 100 g of water at 20° C. is preferably 1 g. Or less, more preferably 0.5 g or less, still more preferably 0.1 g or less, and even more preferably substantially 0 g.
• the non-volatile liquid oily component in the present invention means one having a volatility of 50% or less after drying at 25° C. for 60 minutes under 1 atm, preferably at 25° C. under 1 atm, It has a volatility of 50% or less after drying for 120 minutes.
• the volatilization rate is measured according to German test standard DIN 53249, and specifically, it is carried out by the following procedures 1 to 4. 1.
• the weight (P(g)) of a round filter paper having a diameter of 150 mm is measured. 2.
• a sample of 0.3 g of the component (A) is dropped on a round filter paper with a pipette, and immediately after that, the weight of the filter paper (W 0 (g)) is measured. 3.
• the weight of the filter paper is weighed in the absence of aeration at 25° C., 5 minute intervals, with a weight measurement with an accuracy of about 0.001 g.
• the weight of the filter paper measured 60 minutes after measuring 2 is W 60 (g).
• the volatility (%) is the value derived from the calculation formula ⁇ ((W 0 -P)-(W 60 -P))/(W 0 -P) ⁇ 100. The lower the volatilization rate, the longer the liquid oil component stays when applied to the skin, and the higher the repellent sustaining effect.
• the volatility of the liquid oily component means the volatility of the mixture of two or more liquid oily components. Therefore, as long as the volatilization rate of the mixture is within the above range, liquid oily components having a volatility rate of more than 50% after drying at 25° C. for 60 minutes under 1 atm may be used in combination.
• the surface tension of the component (A) at 25° C. is preferably 15 mN/m or more, more preferably 17 mN/m or more from the viewpoint of availability, and 40 mN/m or less from the viewpoint of improving the repellent sustaining effect. , Preferably 30 mN/m or less, more preferably 28 mN/m or less, further preferably 25 mN/m or less, even more preferably 23 mN/m or less, even more preferably 21 mN/m or less. Further, even if the surface tension at 25° C. itself is more than 40 mN/m by itself, by using a mixture with another liquid oily component, the repellent sustaining effect is exhibited if the surface tension is lowered.
• the viscosity of the component (A) at 23° C. measured by a B-type rotational viscometer is preferably 1 mPa ⁇ s or more from the viewpoint of suppressing volatility and improving the repellency sustaining effect, and from the viewpoint of improving the repellency sustaining effect, 400 mPas ⁇ S or less, preferably 300 mPa ⁇ s or less, more preferably 210 mPa ⁇ s or less, further preferably 100 mPa ⁇ s or less, even more preferably 60 mPa ⁇ s or less, even more preferably 40 mPa ⁇ s or less, even more preferably Is 30 mPa ⁇ s or less.
• the surface tension and viscosity of the component (A) are measured by the methods described in Examples.
• (A) Silicone Oil As the silicone oil, from the viewpoint of improving the repellent sustaining effect, a group consisting of dimethylpolysiloxane, dimethiconol (dimethylpolysiloxane having a hydroxy group at the terminal), methylphenylpolysiloxane, modified silicone, and cyclic silicone. One or more selected from are preferable.
• the modified silicone include amino-modified silicone (dimethylpolysiloxane having an amino group), polyether-modified silicone, glyceryl-modified silicone, amino derivative silicone, carboxy-modified silicone, fatty acid-modified silicone, alcohol-modified silicone, aliphatic alcohol-modified silicone, epoxy. Examples include modified silicone, fluorine-modified silicone, alkyl-modified silicone and the like.
• silicone oils one or more selected from the group consisting of dimethylpolysiloxane, dimethiconol, methylphenylpolysiloxane, and modified silicone is preferable from the viewpoint of improving the repellent sustaining effect, and dimethylpolysiloxane, dimethiconol, and polyether.
• One or more selected from the group consisting of modified silicone is more preferable, and dimethylpolysiloxane is even more preferable.
• dimethylpolysiloxane examples include one or more selected from the group consisting of linear dimethylpolysiloxane and cyclic dimethylpolysiloxane. Among these, linear dimethylpolysiloxane is more preferable from the viewpoint of improving the repellent sustaining effect.
• Examples of commercially available straight-chain dimethylpolysiloxanes are Shin-Etsu Chemical Co., Ltd.'s KF-96 series, Toray Dow Corning's SH200C series, "2-1184 Fluid”, Momentive Performance Materials, Inc. “Silsoft DML”, “Element14 PDMS 5-JC”, “Element14 PDMS 10-JC”, “Element14 PDMS 20-JC” and the like.
• ester oil As an ester oil, from the viewpoint of improving the repellent sustaining effect, an ester oil represented by any of the following general formulas (1) to (3) and a dialkyl represented by the following general formula (4) Carbonate compounds are preferred.
• R 1 may be substituted with a hydroxyl group and is a linear or branched alkyl group having 7 to 23 carbon atoms or an aromatic hydrocarbon group having 6 to 24 carbon atoms.
• R 2 represents a linear or branched alkyl group or alkenyl group having 1 to 22 carbon atoms.
• the number of carbon atoms is preferably 7 or more, more preferably 9 or more, from the viewpoint of improving the repellent sustaining effect, and from the viewpoint of improving the feel when applied to the skin, It is preferably 21 or less, more preferably 17 or less.
• R 1 is an aromatic hydrocarbon group
• the number of carbon atoms is preferably 8 or more, more preferably 10 or more, and preferably 22 or less from the viewpoint of improving the feel when applied to the skin.
• R 2 is preferably a linear or branched alkyl group or alkenyl group having 20 or less carbon atoms, more preferably 18 or less carbon atoms, from the viewpoint of improving the feel when applied to the skin. Further, from the viewpoint of improving the feel when applied to the skin, at least one of R 1 and R 2 is preferably a branched alkyl group.
• ester oil represented by the general formula (1) examples include myristyl 2-ethylhexanoate, cetyl 2-ethylhexanoate, stearyl 2-ethylhexanoate, isodecyl octanoate, isocetyl octanoate, isononyl isononanoate, and isotridecyl isononanoate.
• R 3 O (R 3 O)-CH 2 CH(OR 4 )-CH 2 (OR 5 ) (2)
• R 3 , R 4 and R 5 are each independently a hydrogen atom or a group represented by the following general formula (2-1) and are not all hydrogen atoms. .. -CO-R 6 (2-1)
• R 6 represents an alkyl group or an alkenyl group having 7 or more and 23 or less, preferably 17 or less carbon atoms, which may be substituted by a hydroxyl group.
• Examples of the ester oil represented by the general formula (2) include one or more selected from the group consisting of glyceryl tri-2-ethylhexanoate and glyceryl tricaprylate.
• Jojoba oil olive oil, sunflower oil, soybean oil, peanut oil, rapeseed oil, almond oil, palm oil, coconut oil, castor oil, wheat germ oil, grape seed oil, thistle oil, evening primrose oil, macadamia nut oil, corn germ oil, and It may be a plant-derived ester oil such as avocado oil.
• R 7 O-(AO)m-COR 8 (3)
• R 7 represents an aromatic hydrocarbon group having 6 to 20 carbon atoms
• R 8 represents an alkyl group or alkenyl group having 1 to 23 carbon atoms
• AO represents an alkyleneoxy group having 2 to 4 carbon atoms
• m represents an average added mole number of 1 to 50.
• R 7 preferably has 6 or more carbon atoms from the viewpoint of improving the repellent sustaining effect, and preferably 12 or less, more preferably 10 or less from the viewpoint of improving the feel when applied to the skin.
• R 8 has preferably 7 or more carbon atoms, more preferably 11 or more carbon atoms from the viewpoint of improving the repellent sustaining effect, and preferably 21 or less from the viewpoint of improving the feel when applied to the skin. , And more preferably an alkyl group having 15 or less.
• the AO group is preferably a propyleneoxy group from the viewpoint of improving the repellency sustaining effect, and m is preferably 1 from the viewpoint of improving the repellency sustaining effect and improving the feel when applied to the skin.
• the above is 10 or less, more preferably 1 or more and 5 or less.
• ester oil represented by the general formula (3) examples include benzyl alcohol 3 mol adduct with benzyl alcohol and myristic acid ester (“Kurodamol STS” by Croda Co.), benzyl alcohol 3 mol adduct with 2-ethyl ester.
• benzyl alcohol 3 mol adduct with 2-ethyl ester examples include benzyl alcohol 3 mol adduct with 2-ethyl ester.
• R 9 O—(CH 2 CH 2 O)v—CO—(OCH 2 CH 2 )w—OR 10 (4)
• R 9 and R 10 each independently represent an alkyl group or an alkenyl group having 6 to 22 carbon atoms, and v and w are each independently 0 or an average of 1 to 50. Indicates the number of added moles.
• R 9 and R 10 preferably have 8 or more carbon atoms from the viewpoint of improving the repellent sustaining effect, and preferably 18 or less, and more preferably from the viewpoint of improving the feel when applied to the skin. It is an alkyl group of 12 or less.
• v and w are preferably 0 or a number of 1 or more and 5 or less, and more preferably 0, from the viewpoint of improving the feel when applied to the skin.
• dialkyl carbonate compound represented by the general formula (4) examples include dioctyl carbonate (“Cetirol CC” manufactured by Cognis Corp.).
• ester oils other than the above include esters of polyhydric carboxylic acids and alcohols, esters of polyhydric alcohols other than glycerin and fatty acids, and the like. Specific examples thereof include a group consisting of diisopropyl dimer, diisopropyl adipate, diethoxyethyl succinate, 2-ethylhexyl succinate, propanediol dicaprate, neopentyl glycol dicaprate, neopentyl glycol di2-ethylhexanoate, and the like.
• esters of neopentyl glycol and fatty acids are preferable, and one or more selected from the group consisting of neopentyl glycol dicaprate and neopentyl glycol di2-ethylhexanoate is preferred. More preferable.
• ester oils one or more kinds selected from the group consisting of ester oils represented by the general formula (1) and esters of neopentyl glycol and fatty acids are preferable.
• (C) Ether Oil As the ether oil, a dialkyl ether compound represented by the following general formula (5) or a polyoxyalkylene alkyl ether compound represented by the following general formula (6) is used from the viewpoint of improving the repellent sustaining effect. Is preferred.
• R 11 -OR 12 are each independently a linear or branched alkyl group or alkenyl group having 6 to 22 carbon atoms, or an aromatic hydrocarbon group having 6 to 24 carbon atoms. Indicates. R 11 and R 12 are preferably alkyl groups from the viewpoint of improving the repellency sustaining effect, and their carbon number is preferably 8 or more from the viewpoint of improving the repellency sustaining effect, and applied to the skin. From the viewpoint of improving the feel at the time, it is preferably 18 or less, more preferably 16 or less, still more preferably 12 or less.
• dialkyl ether compound represented by the general formula (5) examples include dihexyl ether, dioctyl ether (“Cetol OE” manufactured by Cognis Co., Ltd.), dicaprylyl ether, cetyl-1,3-dimethylbutyl ether (“ASE-166K” manufactured by Kao Corporation). ]) and the like.
• R 13 represents an alkyl group or an alkenyl group having 6 to 22 carbon atoms
• PO represents a propyleneoxy group
• EO represents an ethyleneoxy group
• r represents an average added mole number of 0.1 or more and 15 or less
• s represents an average added mole number of 0 or more and 10 or less.
• the carbon number of R 13 is preferably 8 or more from the viewpoint of improving the repellent sustaining effect, and preferably 20 or less, more preferably 18 or less from the viewpoint of improving the feel when applied to the skin. And more preferably 12 or less.
• the average added mole number r is preferably 1 or more, more preferably 2 or more, still more preferably 3 or more, from the viewpoint of improving the repellent sustaining effect, and from the viewpoint of improving the feel when applied to the skin. Therefore, it is preferably 13 or less, more preferably 10 or less, and the average addition mole number s is preferably 5 or less, more preferably 1 or less, and further preferably from the viewpoint of improving the feel when applied to the skin. Is 0.
• polyoxyalkylene alkyl ether compound represented by the general formula (6) polypropylene glycol, polyoxypropylene octyl ether, polyoxypropylene decyl ether having an average added mole number r of propyleneoxy groups of 3 or more and 10 or less, And at least one selected from the group consisting of polyoxypropylene lauryl ether.
• the ether oil represented by the general formula (5) is preferable from the viewpoint of improving the repellent sustaining effect.
• hydrocarbon oil examples include liquid paraffin, liquid isoparaffin, squalane, isohexadecane, isoeicosan, hydrogenated polyisobutene, light liquid isoparaffin, heavy liquid isoparaffin, ⁇ -olefin oligomer, and cycloparaffin. .. Among these, at least one selected from the group consisting of liquid paraffin, liquid isoparaffin, and squalane is preferable from the viewpoint of improving the repellent sustaining effect and improving the feel when applied to the skin.
• (E) Aliphatic alcohol As the aliphatic alcohol, a monovalent chain or cyclic aliphatic alcohol can be mentioned, and from the viewpoint of improving the repellent sustaining effect, a monovalent chain aliphatic alcohol is preferable.
• the carbon number of the aliphatic alcohol is preferably 14 or more, more preferably 18 or more, from the viewpoint of improving the repellent sustaining effect, and from the viewpoint of improving the feel when applied to the skin.
• the aliphatic alcohol is preferably 28 or less, more preferably 24 or less, still more preferably 22 or less.
• the aliphatic alcohol may be linear or branched, and may be saturated or unsaturated, but has a good viewpoint of improving the repellent sustaining effect and a good feel when applied to the skin.
• a branched aliphatic saturated alcohol is preferable.
• the straight-chain aliphatic alcohol include oleyl alcohol and the like, and examples of the branched-chain aliphatic saturated alcohol include butyloctanol, butyldecanol, hexyldecanol, octyldodecanol and the like.
• branched-chain aliphatic saturated alcohols are preferable, from the viewpoint of improving the repellent sustaining effect and improving the feel when applied to the skin, consisting of hexyldecanol, hexyldecanol, and octyldodecanol.
• One or more selected from the group is preferable.
• polyhydric alcohol examples include aliphatic alcohols having 2 or more carbon atoms, aromatic alcohols, sugar alcohols having 4 or more carbon atoms, and may be saturated or unsaturated. From the viewpoint of improving the feel when applied to the skin, one or more selected from the group consisting of an aliphatic alcohol having 2 to 10 carbon atoms, an aromatic alcohol, and a sugar alcohol having 4 to 10 carbon atoms preferable.
• aliphatic alcohols having 2 or more carbon atoms include ethylene glycol, propylene glycol, 1,2-butylene glycol, 1,3-butylene glycol, 1,2-pentanediol, 1,2-hexanediol.
• dihydric alcohols such as diethylene glycol, dipropylene glycol, and hexylene glycol.
• sugar alcohol examples include sorbitol, erythritol, pentaerythritol, xylitol, mannitol and the like.
• liquid oily components from the viewpoint of improving the repellent sustaining effect, (a) silicone oil, (b) ester oil, (c) ether oil, (d) hydrocarbon oil, and (f) polyhydric alcohol. At least one selected from the group consisting of (a) silicone oil, (b) ester oil, and (d) hydrocarbon oil is more preferably one or more, and (a) silicone oil and One or more selected from the group consisting of (d) hydrocarbon oils are more preferable, and (a) silicone oils are even more preferable.
• silicone oils one or more selected from the group consisting of dimethylpolysiloxane, dimethiconol, methylphenylpolysiloxane, and modified silicone is preferable, and dimethylpolysiloxane is more preferable, from the viewpoint of improving the repellent sustaining effect. It is at least one selected from the group consisting of siloxane, dimethiconol, and polyether-modified silicone, more preferably dimethylpolysiloxane, and even more preferably linear dimethylpolysiloxane.
• the content of the component (A) in the composition of the present invention is 13% by mass or more, preferably 20% by mass or more, more preferably 25% by mass or more, from the viewpoint of improving the repellent sustaining effect. From the viewpoint of improving the sustaining effect, suppressing the odor derived from component (A), improving the usability of the composition, and ensuring the long-term storage stability of the composition, 99.995% by mass or less, It is preferably 80% by mass or less, more preferably 50% by mass or less, still more preferably 40% by mass or less, still more preferably 35% by mass or less.
• the content of the component (A) in the composition of the present invention is 13 to 99.995% by mass, preferably 13 to 80% by mass, more preferably 13 to 50% by mass, and The amount is preferably 20 to 50% by mass, more preferably 20 to 40% by mass, still more preferably 25 to 35% by mass.
• composition of the present invention contains, as the component (B), one or more repellent essential oils selected from the group consisting of citronella oil, lemongrass oil, eucalyptus oil, peppermint oil, and dog peppermint oil.
• the eucalyptus oil is a repellent essential oil containing eucalyptol oil and lemon eucalyptol oil.
• the "repellent essential oil” means an essential oil having a pest repellent effect, and for example, citronella oil, lemongrass oil, and eucalyptol oil are licensed in Thailand, and mint pepper oil is licensed in the United States as a repellent ingredient. Mint oil is also widely used as a repellent component.
• the "repellent essential oil” includes essential oils (essential oils) obtained by extracting, distilling, or squeezing the components contained in plants, as well as artificially produced synthetic essential oils.
• essential oils essential oils obtained by extracting, distilling, or squeezing the components contained in plants, as well as artificially produced synthetic essential oils.
• citronella oil is from Cymbopogon nardus or Cymbopogon winterianus
• lemongrass oil is from Cymbopogon citratus
• eucalyptus oil is from Eucalyptus citriodora Eucalyptus L'Heritier spp.
• the oil is an essential oil obtained from Nepeta sp. such as Nepeta cataria.
• Citronella oils are described, for example, in R. Tisserand et al.
• Component (B) is an existing repellent essential oil, and its repellent effect is well known. However, if it is contained in the composition in an amount of more than 15% by mass, the pest repellent effect is good, but component (B) is derived. Emits a strong odor, and can cause skin problems such as rashes. On the other hand, when the content of the component (B) in the composition is 15% by mass or less, strong odor derived from the component (B) can be suppressed, but the pest repellent sustaining effect tends to decrease.
• the composition of the present invention even if the content of the component (B) is 15% by mass or less, by using the component (A) in combination, while suppressing a strong odor derived from the component (B), It is possible to secure the repellent sustaining effect and safety.
• the component (B) one type may be used alone, or two or more types may be contained.
• one or more repellent essential oils selected from citronella oil, lemongrass oil, eucalyptus oil, and narwhal oil are preferable from the viewpoint of improving the repellent sustaining effect, and citronella oil, lemongrass oil, and narwhal oil. More preferred is one or more repellent essential oils selected from oils.
• the content of the component (B) in the composition of the present invention is 0.005 mass% or more, and preferably 0 from the viewpoint of improving the repellent sustaining effect and suppressing the odor derived from the component (A). It is 0.006 mass% or more, and more preferably 0.008 mass% or more.
• the content of the component (B) in the composition of the present invention is 15% by mass or less, preferably 10% by mass or less, from the viewpoint of suppressing strong odor and skin troubles derived from the component (B). It is preferably 5% by mass or less, more preferably 2% by mass or less, still more preferably 1% by mass or less, still more preferably 0.5% by mass or less, and even more preferably 0.08% by mass or less.
• the content of the component (B) in the composition of the present invention is 0.005 to 15% by mass, preferably 0.006 to 10% by mass, more preferably 0.006 to 5% by mass, and further It is preferably 0.006 to 2% by mass, more preferably 0.006 to 1% by mass, even more preferably 0.006 to 0.5% by mass, still more preferably 0.008 to 0.08% by mass. is there.
• the composition of the present invention contains the component (A) and the component (B) as repellent components against pest repellent, and does not contain an effective amount of the other pest repellent, so that the user's allergies and rough skin are prevented. It is preferable from the viewpoint of preventing
• the composition of the present invention has a pest repellent sustaining effect even if it does not contain an effective amount of a pest repellent other than the components (A) and (B). In other words, even when the composition of the present invention contains the existing pest repellent other than the components (A) and (B) in an amount less than the lower limit of the effective amount, the pests can be in situ even if they accrete. If the non-retaining property is not retained, the retention suppressing effect of the present invention is exhibited. That is, the composition of the present invention may be substantially free of pest repellents other than the components (A) and (B).
• pest repellents other than components (A) and (B) generally means that the content of pest repellents other than components (A) and (B) is In the composition of the present invention, preferably 10% by mass or less, more preferably 6% by mass or less, further preferably 4% by mass or less, even more preferably 3% by mass or less, still more preferably 2% by mass or less, More preferably, it means 1 mass% or less.
• the effective amount of the existing pest repellent other than the component (B) can also be referred to the minimum effective amount or the like announced by the manufacturer of each repellent product.
• the effective amount of DEET is 4% by mass or more. Therefore, in the present invention, setting the content of N,N-diethyltoluamide to 3% by mass or less is one of the preferred embodiments of the present invention, and is more preferably 1% by mass or less.
• the effective amount of the existing pest repellent can also be measured by the repellent evaluation test described below.
• Repellent evaluation test 100 mated female mosquitoes (Aedes albopictus) are placed in a plastic cage (30 ⁇ 30 ⁇ 30 cm: BugDorm-1 cage) surrounded by a mesh. Approximately 15 cm from the wrist part of Quaratech Super Long Gloves (50 cm) (Azwan Co., Ltd., Catalog number: 3-6432-02) with a 5 cm long ⁇ 4 cm rectangular notch on the elbow side, insert your arm To do.
• a stop of 1 second or more is simply referred to as a stop.
• the test of the evaluation sample which is a solution of the pest repellent, is performed by adjusting the concentration with ethanol so that the evaluation sample can be applied at 2 mg/cm 2 to the exposed skin (5 cm ⁇ 4 cm).
• a solution having a adjusted concentration is placed on the exposed part using a Pipetman and applied so that it is spread over the entire exposed part of the skin (required solution amount: 40 to 50 ⁇ l). After that, let stand for 3 minutes and start the test. The test is performed by inserting the arm coated with the evaluation sample into a cage for 2 minutes and counting the number of stays. The test is terminated when the vehicle is stopped twice in total, and a test is performed in which the arm is inserted for 2 minutes every 30 minutes until the test is completed. If the second retention is performed at 30 minutes, the repellent effect duration is determined to be 0 minutes, and if the second retention is performed at 60 minutes, the repulsion effect duration is determined to be 30 minutes.
• the concentration of the pest repellent showing an average repellent effect duration of 2 hours or more can be defined as the effective concentration (effective amount) of the pest repellent. Since the composition of the present invention has a repellent sustaining effect without containing an effective amount of the pest repellent other than the components (A) and (B), it suppresses unpleasant odors and strong odors derived from the pest repellent. It is more preferable that the pest repellent other than the component (A) and the component (B) is not substantially contained from the viewpoint of preventing the occurrence of skin troubles.
• the content of the pest repellent other than the component (A) and the component (B) is preferably 0.5% by mass or less, more preferably 0.1% by mass or less, and still more preferably 0. It is not more than 01% by mass, and even more preferably substantially 0% by mass.
• the mass ratio [(B)/(A)] of the component (B) to the component (A) improves the repellent sustaining effect and suppresses the odor derived from the component (A). Therefore, it is preferably 0.0001 or more, more preferably 0.0002 or more, and from the viewpoint of suppressing odor, preferably 0.8 or less, more preferably 0.5 or less, still more preferably 0.05 or less. It is more preferably 0.005 or less, and even more preferably 0.0005 or less.
• the mass ratio [(B)/(A)] of the component (B) to the component (A) is preferably 0.0001 to 0.8, more preferably 0.0001 to 0.5, It is more preferably 0.0002 to 0.05, still more preferably 0.0002 to 0.005, and still more preferably 0.0002 to 0.0005.
• the composition of the present invention preferably contains water as the component (C) from the viewpoint of improving the repellent sustaining effect and the composition having a good feeling in use.
• the content of the component (C) in the composition is preferably 5% by mass or more, more preferably 10% by mass or more, further preferably from the viewpoint of improving the repellent sustaining effect and the composition having a good feeling in use. Is 35% by mass or more, more preferably 50% by mass or more. From the viewpoint of improving the repellent sustaining effect, it is preferably 86.995% by mass or less, more preferably 85% by mass or less, still more preferably 80% by mass or less, still more preferably 75% by mass or less. ..
• the content of the component (C) in the composition is preferably 5 to 86.995% by mass, more preferably 5 to 85% by mass, further preferably 10 to 80% by mass, still more preferably 35 to 75% by mass. , And even more preferably 50 to 75% by mass.
• the present invention can be applied to various composition forms, for example, a non-aqueous composition containing no water, a water-in-oil composition, an oil-in-water composition, and the like.
• an oil-in-water type composition is preferable.
• the content of the component (C) in the composition is preferably 35% by mass or more, more preferably 40% by mass or more, further preferably 45% by mass. That is all.
• it is preferably 86.995% by mass or less, more preferably 80% by mass or less, still more preferably 75% by mass or less.
• a water-in-oil type composition is preferable.
• the content of the component (C) in the composition is preferably 5% by mass or more from the viewpoint of improving the feel when applied to the skin, It is more preferably 10% by mass or more, still more preferably 15% by mass or more.
• it is preferably 40% by mass or less, more preferably 30% by mass or less, and further preferably 25% by mass or less. ..
• the mass ratio [(A)/(C)] of the component (A) and the component (C) is preferably from the viewpoint of improving the repellent sustaining effect. Is 0.05 or more, more preferably 0.1 or more, further preferably 0.2 or more, and from the same viewpoint, preferably 20 or less, more preferably 10 or less, still more preferably 5 or less, still more preferably It is 1 or less.
• the mass ratio [(A)/(C)] of the component (A) and the component (C) is preferably 0.05 to 20, more preferably 0.1 to 10, and further preferably It is 0.1 to 5, more preferably 0.2 to 5, and even more preferably 0.2 to 1.
• composition of the present invention may further contain a thickener as the component (D).
• a thickener As the thickener, those having an appropriate emulsifying ability (that is, surfactant ability) are preferable.
• an agent having an emulsifying ability and a thickening effect is a thickener.
• component (D) include water-soluble cationic polymers, anionic polymers, nonionic polymers, and amphoteric polymers or dipolar polymers.
• the content of the component (D) in the composition of the present invention is such that the repellent sustaining effect is improved, that each component is satisfactorily dispersed or dissolved to ensure excellent coatability on the skin, and the composition From the viewpoint of ensuring long-term storage stability, it is preferably 0.01% by mass or more, more preferably 0.05% by mass or more, further preferably 0.1% by mass or more, and from the same viewpoint, preferably 5% by mass. % Or less, more preferably 3% by mass or less, and further preferably 1% by mass or less.
• the content of the other surfactants in the composition is preferably 1.5% by mass or less, more preferably It is 1 mass% or less.
• the composition of the present invention is a component other than the above, for example, a surfactant, an antiseptic, a colorant, a repellent, a repellent essential oil other than the component (B), a moisturizer, a fragrance, within a range that does not impair the effects of the invention.
• a pH adjuster or the like can be contained as appropriate.
• vitamins, blood circulation promoters, active oxygen scavengers, anti-inflammatory agents, whitening agents, bactericidal agents and other medicinal and physiologically active ingredients can also be contained.
• it can be used for other purposes such as using a fragrance as a germicide.
• the composition of the present invention can be produced by a conventional method. For example, it can be produced by mixing the components (A) and (B) and, if necessary, the component (C), a thickener, a surfactant, a volatile oil, etc., and stirring the mixture using a known device. it can.
• the pest targeted by the composition of the present invention is not particularly limited, it is more effective against flying pests.
• “Flying pests” are pests that approach animals such as humans while flying, and suck blood from their skin, pests that carry pathogenic bacteria while flying, even if they do not suck blood, and flying itself is not suitable for humans. Pests that give a pleasant sensation.
• flying pests include mosquitoes such as Culex pipiens, Culex tritaeniorhynchus, Culex pipiens, Culex pipiens, Aedes aegypti, Aedes albopictus, Aedes albopictus, Aedes albopictus, Gambie anopheles mosquito, Black mosquito mosquito, Acacia mosquitoes, Acacia lucidum, Acacia lucidum, Acacia mosquito, Acacia mosquitoes, Acacia mosquitoes.
• mosquitoes such as Culex pipiens, Culex tritaeniorhynchus, Culex pipiens, Culex pipiens, Aedes aegypti, Aedes albopictus, Aedes albopictus, Aedes albopictus, Gambie anopheles mosquito, Black mosquito mosquito, Acacia mosquitoes, Acacia lucidum, Acacia lucidum
• Black flies such as blue flies, flesh flies, flesh flies, black flies, blow flies, flesh flies, sand flies, onion flies, fruit flies, fruit flies, etc.; Nukaka such as Oshimanukaka and chicken Nakaka; bees such as yellow hornet, yellow-tailed wasp and bee.
• the composition of the present invention is particularly excellent in repellent sustaining effect against mosquitoes.
• mosquitoes it has an excellent repellent sustaining effect on Culex pipiens, Culex pipiens, Culex pipiens, Aedes aegypti, Aedes aegypti, and Aedes albopictus.
• the pest repellent method of the present invention is performed by applying the pest repellent composition of the present invention to the surface of human skin. Further, the pest retention control method of the present invention prevents the pest from retaining on the skin of a human by attaching the pest retention control composition of the present invention to the limbs of a pest, particularly a flying pest.
• these methods are also collectively referred to as the “method of the present invention”.
• applying to the skin surface includes not only directly applying the composition to the skin surface with a hand or the like, but also applying the composition to the skin surface by spraying or the like.
• the amount of the composition applied to the skin surface is preferably 0.1 mg or more, more preferably 0.2 mg or more, still more preferably 0.25 mg or more per 1 cm 2 from the viewpoint of improving the repellent sustaining effect. ..
• the upper limit of the coating amount is preferably 10 mg or less, more preferably 8 mg or less, still more preferably 5 mg or less per 1 cm 2 from the viewpoint of suppressing stickiness and economical efficiency.
• the composition of the present invention has excellent repellent persistence effect against mosquitoes, is safe, suppresses strong odors derived from repellent components, and from the viewpoint of providing a repellent composition excellent in usability, the following components (A) to (C) are provided. It is preferable that the oil-in-water type mosquito repellent composition or the mosquito retention control composition contains 10% by mass or less of the pest repellent other than the components (A) and (B).
• the composition of the present invention has excellent repellent persistence effect against mosquitoes, is safe, suppresses strong odors derived from repellent components, and from the viewpoint of providing a repellent composition excellent in usability, the following components (A) to (C) are provided. And the mass ratio [(A)/(C)] of the component (A) and the component (C) is 0.2 or more and 5 or less, and pest repellent other than the component (A) and the component (B) is avoided. It is preferable that the composition is an oil-in-water type mosquito repellent composition or a mosquito retention-preventing composition having an agent content of 10% by mass or less.
• the composition of the present invention has excellent repellent persistence effect against mosquitoes, is safe, suppresses strong odors derived from repellent components, and from the viewpoint of providing a repellent composition excellent in usability, the following components (A) to (C) are provided.
• the mass ratio [(B)/(A)] of the component (B) to the component (A) is 0.0001 or more and 0.5 or less, and the mass of the component (A) and the component (C).
• the ratio [(A)/(C)] is 0.2 or more and 5 or less, and the content of the pest repellent other than the component (A) and the component (B) is 10% by mass or less, an oil-in-water type It is preferably a mosquito repellent composition or a mosquito retention prevention composition.
• the composition of the present invention has excellent repellent persistence effect against mosquitoes, is safe, suppresses strong odor derived from repellent components, and provides a repellent composition having excellent feeling of use, and the following components (A) to (D) And the mass ratio [(B)/(A)] of the component (B) to the component (A) is 0.0001 or more and 0.5 or less, and the mass of the component (A) and the component (C).
• the ratio [(A)/(C)] is 0.2 or more and 5 or less, and the content of the pest repellent other than the component (A) and the component (B) is 10% by mass or less, an oil-in-water type It is preferably a mosquito repellent composition or a mosquito retention prevention composition.
• Non-volatile liquid oily component of: 13% by mass or more and 50% by mass or less
• D) thickener 0.05 mass% or more and 3 mass% or less
• the pest repellent method of the present invention is a method of repelling a pest insect even if the pest insect such as a mosquito accretes on an object to which the composition of the present invention is applied or attached, because the pest insect does not stay in place. Specifically, it is said that pests such as mosquitoes do not stay on the skin surface of animals for a time that allows insertion of a needle after accretion on the skin of animals such as humans, specifically, for example, 1 second or longer. It has an effect of suppressing retention. Such an effect is based on a pest repellent principle which has not existed in the past, and is safe without side effects such as rough skin.
• the present invention further discloses the following embodiments.
• An oil-in-water type that contains the following components (A) and (B) and has a mass ratio [(B)/(A)] of the component (B) to the component (A) of 0.0001 or more and 0.8 or less.
• a pest repellent composition or a pest retention inhibiting composition is disclosed.
• the mass ratio [(B)/(A)] of the component (B) to the component (A) is 0.0002 or more, preferably 0.0003 or more, and 0.5 or less, preferably 0.05 or less, more preferably Is 0.005 or less, more preferably 0.0005 or
• the content of the pest repellent other than the components (A) and (B) is 10% by mass or less, preferably 6% by mass or less, more preferably 4% by mass or less, further preferably 3% by mass or less, still more preferably
• the composition according to ⁇ 3>, wherein the pest repellent other than the components (A) and (B) is DEET.
• the viscosity of the component (A) at 23° C. measured by a B-type rotational viscometer is 1 mPa ⁇ s or more and 300 mPa ⁇ s or less, preferably 210 mPa ⁇ s or less, more preferably 100 mPa ⁇ s or less, further preferably 60 mPa ⁇ s.
• composition according to any one of ⁇ 1> to ⁇ 5> which is more preferably 40 mPa ⁇ s or less, still more preferably 30 mPa ⁇ s or less.
• Component (A) is one or more selected from the group consisting of silicone oil, ester oil, ether oil, and hydrocarbon oil, preferably one or more selected from the group consisting of silicone oil, ester oil, and hydrocarbon oil,
• the composition according to any one of ⁇ 1> to ⁇ 6> which is more preferably one or more selected from the group consisting of silicone oils and hydrocarbon oils, and further preferably silicone oils.
• Component (B) is at least one selected from the group consisting of citronella oil, lemongrass oil, eucalyptus oil, and mint oil, and preferably one or more selected from the group consisting of citronella oil oil, lemongrass oil, and mint oil.
• the content of the component (B) is 0.006 mass% or more, preferably 0.008 mass% or more, and 10 mass% or less, preferably 5 mass% or less, more preferably 2 mass% or less, and further preferably 1
• the content of the component (C) is 5% by mass or more, preferably 10% by mass or more, more preferably 35% by mass or more, further preferably 50% by mass or more, and 86.995% by mass or less, preferably 85% by mass.
• composition according to ⁇ 11> or ⁇ 12> which is 995% by mass or less, preferably 80% by mass or less, more preferably 75% by mass or less.
• ⁇ 14> It is a water-in-oil type composition, and the content of the component (C) in the composition is 5% by mass or more, preferably 10% by mass or more, more preferably 15% by mass or more, and 40% by mass or less, preferably Is 30 mass% or less, more preferably 25 mass% or less, the composition according to ⁇ 11> or ⁇ 12>.
• the mass ratio [(A)/(C)] of the component (A) and the component (C) is 0.05 or more, preferably 0.1 or more, more preferably 0.2 or more, and 20 or less, preferably The composition according to any one of ⁇ 11> to ⁇ 14>, which is 10 or less, more preferably 5 or less, and further preferably 1 or less.
• a thickener is preferably added in an amount of 0.01% by mass or more, more preferably 0.05% by mass or more, further preferably 0.1% by mass or more, and preferably 5% by mass or less, more preferably 3% by mass.
• composition according to any one of ⁇ 1> to ⁇ 15>, which is contained in an amount of 1% by mass or less, more preferably 1% by mass or less.
• An oil-in-water type mosquito repellent composition or mosquito repellent control which contains the following components (A) to (C) and contains 10% by mass or less of a pest repellent other than the components (A) and (B). Composition.
• the following components (A) to (C) are contained, and the mass ratio [(A)/(C)] of the components (A) and (C) is 0.2 or more and 5 or less, and the components (A) And
• A One or more selected from the group consisting of silicone oils, ester oils, and hydrocarbon oils having a surface tension of 40 mN/m or less at 25° C. and a viscosity at 23° C. of not more than 400 mPa ⁇ s by a B type rotational viscometer.
• Non-volatile liquid oily component of: 13% by mass or more and 50% by mass or less
• B one or more repellent essential oils selected from the group consisting of citronella oil, lemongrass oil, eucalyptus oil, and mint oil: 0.005% by mass or more 15% by mass or less
• C Water: 35% by mass or more and 86.995% by mass or less
• D Thickener: 0.05% by mass or more and 3% by mass or less ⁇ 21>
• a method for repelling harmful insects which comprises applying the composition according to any one of ⁇ 1> to ⁇ 20> to the surface of human skin.
• ⁇ 22> A method for suppressing the retention of pests, which prevents the pests from staying on human skin by attaching the composition according to any one of ⁇ 1> to ⁇ 20> to the limbs of the pests.
• the surface tension of the liquid oily component is a surface tension measured in an environment of 25° C. by an Wilhelmy method using a platinum plate using an automatic surface tensiometer “Tensiometer K100” (KRUSS).
• Viscosity of liquid oil component As a B-type rotational viscometer according to JIS K7117-1:1999, Toki Sangyo Co., Ltd. "Viscometer TVB-10" was used. It is difficult to accurately measure all the components to be measured under one measurement condition because the viscosity values of the respective components differ greatly from sample to sample. Then, it measured using two types of rotors. The viscosity was first measured using a rotor M2 in a 23° C. environment at a rotation speed of 12 rpm. At this time, a component having a viscosity of 2500 mPa ⁇ s or more was measured again at a rotation speed of 6 rpm to obtain a viscosity value.
• a component having a viscosity of 20 mPa ⁇ s or less was measured again by using an L adapter, which is a rotor for low viscosity, at a rotation speed of 30 rpm under an environment of 23° C. to obtain a viscosity value. ..
• pupae were collected with a dropper, transferred to a 20 mL plastic cup, and transferred to a cage with a net.
• the pupae were fed with adult foods containing 10% by mass sucrose in a 25 mL plastic tube.
• males and females were bred in the same cage for 5 days for mating.
• adult worms were collected using a fluke tube, males and females were visually separated after anesthesia on ice for 5 minutes, and only females were collected and used for evaluation.
• the test was terminated when the test was stopped twice in total, and the test was exposed for 2 minutes every 30 minutes until the test was completed. If the second retention is during the 30th minute exposure, the repellent effect duration is determined to be 0 minutes, and if the second retention is performed at the 60th minute exposure, the repellent effect duration is 30 minutes. It was judged. The test was carried out by three test subjects, and the average duration of repellent effect was calculated.
• the test product was applied to the 4.5 ⁇ 4.5 cm surface of the inner part of the human forearm at a dose of 2 mg/cm 2 .
• the odor intensity was determined by sensory evaluation by three evaluators.
• the odor intensity is evaluated on a 6-point scale (5: intense odor, 4: strong odor, 3: odor that can be easily perceived, 2: weak odor that indicates what odor it is, 1: barely perceptible odor, 0: odorless) Evaluation was performed, and the average value of the evaluations by the three evaluators was taken as the odor intensity.
• the odor intensity suitable for skin application was classified as follows. The smaller the number, the better the composition. A: 2.5 or less B: 2.5 or more and 3.5 or less C: 3.5 or more
• Examples 1-36, Comparative Examples 1-9 (Production and evaluation of compositions)
• the components shown in Table 1 were blended in the blending amounts shown in Tables 2 to 7, and the stirring section of TK Robomix (Tokushu Kika Kogyo Co., Ltd.) was changed to TK Homomixer MARKII 2.5 type.
• the oil-in-water type composition of each example was obtained through the step of stirring for 2 minutes at 8,000 rpm using the replaced one.
• the notations (A) to (D) described in the table correspond to the components (A) to (D) in the present specification, respectively.
• the blending amounts shown in Tables 2 to 7 are the active ingredient amounts (mass %) of each component.
• Various evaluations were performed by the above methods using the obtained compositions. The results are shown in Tables 2-7.
• compositions of the present invention (Examples 1 to 36) containing predetermined amounts of the components (A) and (B) have a pest repellent time of 2 hours or longer, and have an excellent repellent sustaining effect, and It can be seen that the odor derived from the repellent component is suppressed.
• pests particularly excellent repellent persistence effect against flying pests, safe, and strong odor derived from repellent components is suppressed, pest repellent composition suitable for application to the skin, pest retention control composition, A pest repellent method and a pest retention restraint method can be provided.

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• 2019
  • 2019-12-19 JP JP2019228898A patent/JP7465086B2/ja active Active
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