WO2020013281A1 - Système de circulation endoscopique de perfusat - Google Patents

Système de circulation endoscopique de perfusat Download PDF

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Publication number
WO2020013281A1
WO2020013281A1 PCT/JP2019/027518 JP2019027518W WO2020013281A1 WO 2020013281 A1 WO2020013281 A1 WO 2020013281A1 JP 2019027518 W JP2019027518 W JP 2019027518W WO 2020013281 A1 WO2020013281 A1 WO 2020013281A1
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Prior art keywords
perfusate
endoscope
perfusion
circulation
circulation system
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PCT/JP2019/027518
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English (en)
Japanese (ja)
Inventor
佳彦 平尾
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ニプロ株式会社
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Application filed by ニプロ株式会社 filed Critical ニプロ株式会社
Priority to JP2020530259A priority Critical patent/JP7409306B2/ja
Publication of WO2020013281A1 publication Critical patent/WO2020013281A1/fr

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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B1/00—Instruments for performing medical examinations of the interior of cavities or tubes of the body by visual or photographical inspection, e.g. endoscopes; Illuminating arrangements therefor
    • A61B1/12—Instruments for performing medical examinations of the interior of cavities or tubes of the body by visual or photographical inspection, e.g. endoscopes; Illuminating arrangements therefor with cooling or rinsing arrangements
    • G—PHYSICS
    • G02—OPTICS
    • G02B—OPTICAL ELEMENTS, SYSTEMS OR APPARATUS
    • G02B23/00—Telescopes, e.g. binoculars; Periscopes; Instruments for viewing the inside of hollow bodies; Viewfinders; Optical aiming or sighting devices
    • G02B23/24—Instruments or systems for viewing the inside of hollow bodies, e.g. fibrescopes

Definitions

  • the present invention relates to a perfusion fluid circulation system for an endoscope.
  • Patent Document 1 Japanese Patent Application Laid-Open No. 2009-136380 (Patent Document 1) is a prior document that discloses an epidural cooling system in which a part of a perfusate circulation channel is formed in a catheter.
  • the epidural cooling system described in Patent Document 1 includes a cooling catheter, a pump, a heat exchanger, and a cooler.
  • the pipe is connected from the outlet of the heat exchanger to the inlet of the cooling catheter, and the pipe is connected from the outlet of the cooling catheter to the inlet of the heat exchanger.
  • the inlet of the cooling catheter and the outlet of the cooling catheter communicate in the cooling catheter. These form a circulation channel for the perfusate through the cooling catheter, the pump and the heat exchanger.
  • the perfusion solution is used as a refrigerant, and no consideration is given to circulating and using the perfusion solution used for endoscopic surgery.
  • the present invention has been made in view of the above problems, and an object of the present invention is to provide a perfusion solution circulation system for an endoscope, which allows circulation of a perfusion solution used for endoscopic surgery.
  • the perfusion liquid circulation system for an endoscope includes an endoscope, a circulation flow path, a filter, a pump, and a deaeration unit.
  • the circulation channel is connected to the endoscope.
  • the circulation channel absorbs the perfusate sent from the endoscope to the outside, and makes it available for circulation.
  • the filter is provided in the circulation channel.
  • the filter filters the perfusate.
  • the pump is provided in the circulation channel.
  • the pump circulates the perfusate.
  • the deaeration unit is provided in the circulation channel.
  • the degassing unit degass the perfusate.
  • the degassing unit has a net that prevents passage of foreign matter in the perfusate.
  • the degassing unit further has an inlet for the perfusate, an outlet for the perfusate, and a weir standing upright in the degasser. In the deaeration section, the inflow port is located on the opposite side of the outflow port with respect to the weir section.
  • the degassing unit further has a float air trap.
  • the perfusion liquid circulation system for an endoscope further includes a first liquid storage unit and a second liquid storage unit. The first liquid storage part and the second liquid storage part are provided in the circulation channel. The first liquid storage part and the second liquid storage part can store the perfusate.
  • an on-off valve is provided at a position between the first liquid storage part and the second liquid storage part in the circulation flow path.
  • a first pressure measuring device is provided at a position between the first liquid storage section and the endoscope in the circulation flow channel.
  • a second pressure measuring device is provided at a position between the deaeration section and the filter in the circulation flow path.
  • a flushing circuit for flushing the filter is connected to the filter.
  • the perfusate used for endoscopic surgery can be recycled.
  • FIG. 1 is a circuit diagram showing a configuration of an endoscope perfusate circulation system according to a first embodiment of the present invention. It is a front view showing the composition of the deaeration part with which the perfusate circulation system for endoscopes concerning Embodiment 1 of the present invention is provided. It is a front view showing the composition of the deaeration part with which the perfusate circulation system for endoscopes concerning Embodiment 2 of the present invention is provided. It is a front view showing the state before perfusion fluid flows in the deaeration part with which the perfusion fluid circulation system for endoscopes concerning Embodiment 2 of the present invention is provided. FIG.
  • FIG. 10 is a front view showing a state in which a perfusate flows in and a gas in a chamber is exhausted in a deaeration unit provided in the endoscope perfusion solution circulation system according to the second embodiment of the present invention. It is a front view showing the closed state in the deaeration part with which the perfusate circulation system for endoscopes concerning Embodiment 2 of the present invention is provided. It is a front view showing the state where it shifted to the open state from the closed state in the deaeration part with which the perfusate circulation system for endoscopes concerning Embodiment 2 of the present invention is provided.
  • FIG. 1 is a circuit diagram showing a configuration of an endoscope perfusate circulation system according to Embodiment 1 of the present invention.
  • FIG. 2 is a front view showing a configuration of a deaeration unit provided in the endoscope perfusate circulation system according to the first embodiment of the present invention.
  • the perfusate circulation system 100 for an endoscope includes an endoscope 110, a circulation channel 120, a pump 130, a deaerator 140. , A filter 150.
  • the endoscope 110 is provided with an objective lens 111, an injection nozzle 112 for spraying a perfusion liquid onto the objective lens 111 to wash the objective lens 111, and a suction unit 113 for sucking the injected perfusion liquid. .
  • the circulation channel 120 is connected to the endoscope 110. Specifically, one end of the circulation channel 120 is connected to the suction unit 113 of the endoscope 110, and the other end of the circulation channel 120 is connected to the ejection nozzle 112 of the endoscope 110. Thus, the circulation channel 120 absorbs the perfusate sent from the endoscope 110 to the outside, and makes the perfusion solution available for circulation.
  • the circulation channel 120 includes a first channel portion L1, a second channel portion L2, a third channel portion L3, a fourth channel portion L4, and a fifth channel portion L5. It is composed of
  • the pump 130 is provided in the first flow path portion L1 of the circulation flow path 120. Pump 130 circulates the perfusate.
  • the pump 130 is a rotary pump.
  • the pump 130 is not limited to a rotary pump, and may be a gear pump.
  • the degassing unit 140 is provided in the circulation flow channel 120.
  • the deaeration unit 140 is connected to the suction unit 113 of the endoscope 110 by the first flow path L1.
  • the degassing unit 140 degass the perfusate.
  • the configuration of the degassing unit 140 is not limited to the configuration described below, and is configured by, for example, a drip chamber capable of degassing the perfusate. Is also good.
  • the filter 150 is provided in the circulation channel 120.
  • the filter 150 is connected to the degassing unit 140 by the second flow path unit L2.
  • the filter 150 filters the perfusate.
  • the filter 150 has an activated carbon column, and direct hemoperfusion (DHP) is performed in the filter 150.
  • DHP direct hemoperfusion
  • the configuration of the filter 150 is not limited to the above configuration, and may be any configuration that can remove blood cells, bacteria, and the like from the perfusate.
  • the wastewater channel 121 through which the wastewater separated from the perfusate flows is connected to the filter 150.
  • a blood volume measuring unit 180 is provided in the waste liquid channel 121.
  • Blood volume measuring section 180 has an absorbance flow cell.
  • the blood volume measurement unit 180 measures the absorption spectrum of the blood in the waste liquid using an absorbance flow cell, thereby measuring the blood volume in the waste liquid.
  • the configuration of blood volume measuring section 180 is not limited to the above configuration, and may be any configuration that can measure the blood volume in the waste liquid.
  • the blood volume measurement unit 180 does not necessarily have to be provided.
  • the endoscope perfusate circulation system 100 further includes a first liquid storage unit 160 and a second liquid storage unit 161.
  • the first liquid storage section 160 and the second liquid storage section 161 are provided in the circulation channel 120.
  • the first liquid storage section 160 and the second liquid storage section 161 can store a perfusate.
  • an unused perfusion liquid such as saline or lactated Ringer's solution is stored in each of the first liquid storage section 160 and the second liquid storage section 161. I have.
  • the second liquid storage part 161 is connected to the filter 150 by the third flow path part L3.
  • the first liquid storage section 160 and the second liquid storage section 161 are connected to each other by a fourth flow path section L4.
  • the fourth flow path section L4 is provided with an on-off valve 129 for opening and closing the fourth flow path section L4. That is, the on-off valve 129 is provided at a position between the first liquid storage part 160 and the second liquid storage part 161 in the circulation flow channel 120.
  • the first liquid storage section 160 is connected to the ejection nozzle 112 of the endoscope 110 by a fifth flow path section L5. Note that the on-off valve 129 is not necessarily provided.
  • the endoscope perfusate circulation system 100 further includes a bubble detector 170.
  • the bubble detector 170 is provided in the circulation channel 120.
  • the bubble detector 170 is provided in the first flow path portion L1 and is configured integrally with the pump 130.
  • the bubble detector 170 detects that the perfusate flowing through the first flow path portion L1 contains bubbles, the driving of the pump 130 is stopped. Note that the bubble detector 170 does not necessarily have to be provided.
  • the deaeration unit 140 has an inflow port 142 for the perfusate, an outflow port 143 for the perfusion solution, and a weir 144 set up inside the deaeration unit 141.
  • the inflow port 142 is located on the opposite side of the outflow port 143 with respect to the weir section 144.
  • the degassing unit 140 has a chamber 141.
  • the chamber 141 is provided with an inlet 142 and an outlet 143.
  • the first flow path portion L1 is connected to the inflow port 142.
  • the outlet 143 is connected to the second flow path portion L2.
  • a weir portion 144 is provided on the bottom surface of the chamber 141 so as to separate the inflow port 142 side and the outflow port 143 side.
  • the perfusate 10 flowing from the inflow port 142 is stored in a region T ⁇ b> 1 on the inflow port 142 side divided by the weir 144, and the perfusate 10 that has overflowed beyond the weir 144 is discharged out of the chamber 141. Move to the region T2 on the 143 side.
  • the degassing unit 140 further has a net 145 that prevents passage of the foreign matter 11 in the perfusate 10.
  • the mesh portion 145 is arranged in a region T1 on the inflow port 142 side in the chamber 141.
  • the net portion 145 is disposed so as to face the bottom surface of the chamber 141.
  • the perfusate 10 flowing into the region T1 on the inlet 142 side in the chamber 141 passes through the net 145 and moves to the region T2 on the outlet 143 side.
  • foreign matter 11 such as blood clots or tissue fragments contained in the perfusion 10 is captured by the mesh 145.
  • An exhaust pipe 146 is provided above the chamber 141.
  • the exhaust pipe 146 is provided with an on-off valve 147 for opening and closing the exhaust pipe 146.
  • the on-off valve 147 When the on-off valve 147 is opened, the gas 12 separated from the perfusion liquid 10 in the chamber 141 is exhausted through the exhaust pipe 146, and the perfusion liquid 10 is degassed.
  • the reason why the perfusion solution 10 is degassed is that the endoscope 110 is removed from the catheter during the endoscopic operation, and it is necessary to remove air mixed in the perfusion solution at this time.
  • a photoelectric sensor 190 is detachably attached to the outer periphery of the chamber 141.
  • the photoelectric sensor 190 includes a low-order detection unit 191 and a high-order detection unit 192.
  • the photoelectric sensor 190 is electrically connected to the sequencer 193 by a wiring 194.
  • the sequencer 193 is electrically connected to the on-off valve 147 by the wiring 195.
  • the perfusion liquid 10 is discharged from the exhaust pipe 146.
  • the deaeration of the perfusate 10 can be continuously performed while suppressing the discharge of the perfusate.
  • the pump 130, the degassing unit 140, the filter 150, the first liquid storage unit 160, and the second liquid storage unit 161 are supported by the support 2.
  • the first liquid storage section 160 and the second liquid storage section 161 are suspended by an arm section 3 provided at the upper end of the column 2.
  • the first pressure measuring device 123 is provided at a position between the first liquid storage part 160 and the endoscope 110 in the circulation flow channel 120.
  • the first chamber 122 is provided in the fifth flow path portion L5.
  • the first chamber 122 is provided with a first pressure measuring device 123 for measuring the pressure in the first chamber 122.
  • the driving of the pump 130 stops.
  • the pump 130 can be driven. Note that the first pressure measuring device 123 does not necessarily have to be provided.
  • a second pressure measurement device 125 is provided at a position between the deaeration unit 140 and the filter 150 in the circulation flow channel 120. Specifically, a second chamber 124 is provided in the second flow path portion L2. The second chamber 124 is provided with a second pressure measuring device 125 for measuring the pressure in the second chamber 124.
  • the driving of the pump 130 stops.
  • the pump 130 can be driven. Note that the second pressure measuring device 125 is not necessarily provided.
  • a flushing circuit 151 for flushing the filter 150 is connected to the filter 150.
  • the flushing circuit 151 flushes the filter 150 by supplying the cleaning liquid to the filter 150 manually or automatically.
  • the flushing circuit 151 includes, for example, a prefilled syringe filled with a physiological saline as a cleaning liquid.
  • the flushing circuit 151 is automatically controlled, for example, the opening and closing of the clamp of the tube connecting the prefilled syringe and the filter 150 is automatically controlled. While the flushing circuit 151 is flushing the filter 150, the driving of the pump 130 is stopped. Note that the flushing circuit 151 is not necessarily provided.
  • the perfusate supplied from the first liquid storage unit 160 to the ejection nozzle 112 of the endoscope 110 through the fifth flow path L5 is sprayed onto the objective lens 111.
  • the pump 130 is driven in the direction indicated by the arrow 1 in FIG. 1, the perfusate sucked from the suction unit 113 of the endoscope 110 passes through the first flow path unit L1 and passes through the deaeration unit 140.
  • the gas flows from the inflow port 142 into a region T1 in the chamber 141 on the inflow port 142 side.
  • the perfusate 10 that has flowed into the region T1 on the inlet 142 side in the chamber 141 passes through the net 145 and rises in the chamber 141. At this time, the foreign matter 11 contained in the perfusate 10 is captured by the net 145 and removed from the perfusate 10. The perfusate 10 that has overflowed beyond the weir 144 flows into the region T2 on the outlet 143 side in the chamber 141. Thus, while the perfusate 10 flows through the chamber 141, the gas 12 in the perfusion solution 10 is separated, and the perfusion solution 10 is degassed.
  • the cleaned perfusate flows out into the third flow path section L3, and the perfusate that has passed through the third flow path section L3 is stored in the second storage section 161.
  • the waste liquid flows out into the waste liquid flow path 121, and the blood volume in the waste liquid is measured by the blood volume measurement unit 180.
  • the on-off valve 129 When the amount of the perfusate stored in the first storage unit 160 decreases and it becomes necessary to replenish the first storage unit 160 with the perfusion solution, the on-off valve 129 is opened, and the second storage unit is opened.
  • the perfusate stored in the liquid storage 161 is supplied to the first liquid storage 160 through the fourth flow path L4.
  • the on-off valve 129 may be configured to open and close in conjunction with the driving of the pump 130.
  • the driving of the pump 130 is temporarily stopped, and when the measured value of the first pressure measuring device 123 falls below the third threshold value, the pump 130 Is restarted.
  • the driving of the pump 130 is temporarily stopped.
  • the flushing circuit 151 is automatically controlled, the cleaning liquid is automatically supplied from the flushing circuit 151 to the filter 150 when the measured value of the second pressure measuring device 125 exceeds the second threshold value. Flushing is performed.
  • the flushing circuit 151 is manually controlled, a warning is issued when the measured value of the second pressure measuring device 125 exceeds the second threshold, so that the flushing circuit 151 supplies the cleaning liquid to the filter 150 manually. Then, the flushing of the filter 150 is performed. The cleaning liquid used for flushing flows out to the waste liquid channel 121. After the flushing of the filter 150 is completed, the driving of the pump 130 is restarted.
  • the perfusion solution circulation system 100 for an endoscope can circulate and use the perfusion solution used for endoscopic surgery. Thereby, the required amount of the perfusate can be reduced.
  • the perfusate is degassed by the degassing unit 140, even if the endoscope 110 is withdrawn from the catheter during the endoscopic operation and a large amount of air is sucked from the suction unit 113, Since the air mixed in the perfusate can be exhausted by the deaeration unit 140, the circulation use of the perfusate can be continued.
  • the degassing unit 140 is configured such that the perfusate 10 overflowing from the region T1 on the inlet 142 side over the weir 144 moves to the region T2 on the outlet 143 side.
  • the perfusion solution 10 can be stirred to effectively deaerate the perfusion solution 10.
  • the on-off valve 129 is provided in the fourth flow path section L4 connecting the first liquid storage section 160 and the second liquid storage section 161, only the unused perfusate is supplied to the circulation flow path 120. It is possible to selectively switch between a state in which a mixed solution of an unused perfusate and a regenerated perfusate is supplied to the circulation channel 120.
  • the blood volume measurement unit 180 By continuously measuring the blood volume in the waste liquid by the blood volume measurement unit 180, the amount of bleeding of the patient during the endoscopic operation can be monitored.
  • the first pressure measuring device 123 When the measured value of the first pressure measuring device 123 exceeds the first threshold value, the driving of the pump 130 is stopped, so that the pressure of the perfusate at the endoscopic surgical site is increased, so that the wound surface, particularly the rupture, It is possible to suppress the occurrence of water poisoning or abnormal blood electrolyte concentration due to inflow of the perfusate from the vein that has been made. Further, the first pressure measuring device 123 can manage an appropriate flow rate and flow pressure of the perfusate in the observation tissue of the endoscope.
  • the clogging of the filter 150 can be detected.
  • the endoscopic operation can be continued without replacing the filter 150.
  • the perfusate circulation system for an endoscope according to the second embodiment of the present invention mainly has a point that the deaeration unit has a float air trap, and the perfusion solution circulation system for an endoscope according to the first embodiment of the present invention. Since the configuration is different from the system 100, the description of the same configuration as that of the endoscope perfusate circulation system 100 according to the first embodiment of the present invention will not be repeated.
  • FIG. 3 is a front view showing a configuration of a deaeration unit provided in the perfusate circulation system for an endoscope according to the second embodiment of the present invention.
  • the deaeration unit 240 included in the perfusate circulation system for an endoscope according to the second embodiment of the present invention further includes a float air trap.
  • the degassing unit 240 is not provided with the photoelectric sensor 190, the sequencer 193, the on-off valve 147, the wiring 194, and the wiring 195 according to the first embodiment.
  • the float type air trap included in the deaeration unit 240 includes a spherical float 241, a valve body 242, a float guide 243, a valve box 244, a valve seat 245, and a valve body receiving unit 246.
  • the valve seat 245 has an opening 245h.
  • the valve seat 245 is connected to the lower end of the exhaust pipe 146 such that the opening 245h communicates with the inside of the exhaust pipe 146.
  • the valve box 244 has an annular outer shape.
  • the upper end of the valve box 244 is connected to the valve seat 245 so that the valve box 244 is covered by the valve seat 245.
  • An opening 244h is provided at the lower end of the valve box 244.
  • the opening 244h is formed in such a size that a lower end of a valve body 242 described later can pass through.
  • An annular valve body receiving portion 246 is fixed inside the valve box 244.
  • the float guide 243 has an annular outer shape.
  • the upper end of the float guide 243 is connected to the lower end of the valve box 244 so that the inside of the float guide 243 communicates with the inside of the valve box 244.
  • An opening 243h is provided at the lower end of the float guide 243.
  • the opening 243h is formed in such a size that the float 241 does not fall off.
  • the inside of the chamber 141 and the inside of the exhaust pipe 146 communicate with each other through an area Ta surrounded by the float guide 243, the valve box 244, and the valve seat 245.
  • the float 241 is arranged in the float guide 243.
  • the float 241 is provided so as to be able to move up and down according to the liquid level of the perfusion liquid 10 in the chamber 141.
  • the valve element 242 is arranged in the valve box 244.
  • the valve body 242 has a flange portion 242f and an upper end surface 242t.
  • the valve body 242 is inserted into the inside of the valve body receiving portion 246 from above, and the flange portion 242f is located on the valve body receiving portion 246.
  • the lower end 242 b of the valve body 242 contacts the float 241.
  • the valve element 242 is configured to be selectively movable between a closed state in which the upper end surface 242t closes the opening 245h by rising with the rise of the float 241 and an open state in which the upper end surface 242t does not close the opening 245h. Have been.
  • FIG. 4 is a front view showing a state before a perfusate flows in a degassing unit provided in the perfusate circulation system for an endoscope according to the second embodiment of the present invention.
  • the float 241 is It is supported by the float guide 243 while being positioned so as to close the opening 243h.
  • the valve body 242 is supported by the valve body receiving portion 246.
  • FIG. 5 is a front view showing a state in which the perfusate flows in and the gas in the chamber is exhausted in the deaeration unit provided in the endoscope perfusate circulation system according to the second embodiment of the present invention.
  • FIG. 6 is a front view showing a closed state of the deaeration unit provided in the endoscope perfusate circulation system according to the second embodiment of the present invention. As shown in FIG. 6, while the valve body 242 rises as indicated by the arrow 4 and the opening 245h is closed with the rise in the level of the perfusate 10, the gas 12 in the chamber 141 is closed. Not exhausted.
  • FIG. 7 is a front view showing a state in which the deaeration unit included in the perfusate circulation system for an endoscope according to the second embodiment of the present invention has shifted from a closed state to an open state.
  • the gas 12 in the chamber 141 increases in the closed state and the pressure of the gas 12 increases, the liquid level of the perfusate 10 is pushed down as shown in FIG.
  • the valve body 242 descends as shown by the arrow 5, so that the valve body 242 enters an open state in which the opening 245h is not closed.
  • the gas 12 in the chamber 141 is exhausted through the opening 245h and the exhaust tube 146.
  • the degassing unit 240 is automatically opened and closed according to the pressure of the gas 12 in the chamber 141 to perform exhaust.
  • the deaeration unit 240 since the deaeration unit 240 has a float air trap, it is necessary to provide electric devices such as the photoelectric sensor 190, the sequencer 193, and the on-off valve 147 as in the deaeration unit 140 according to the first embodiment. Therefore, the deaeration unit 240 can have a simple configuration.

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Abstract

Ce système de circulation endoscopique de perfusat comprend : un endoscope (110) ; un canal de circulation (120) ; un filtre (150) ; une pompe (130) ; et une unité de dégazage (140). Le canal de circulation (120) est relié à l'endoscope (110). Le canal de circulation (120) absorbe un perfusat envoyé par l'endoscope (110) à l'extérieur et rend celui-ci disponible pour la circulation. Le filtre (150) est prévu pour le canal de circulation (120). Le filtre (150) filtre le perfusat. La pompe (130) est prévue pour le canal de circulation (120). La pompe (130) fait circuler le perfusat. L'unité de dégazage (140) est prévue pour le canal de circulation (120). L'unité de dégazage (140) dégaze le perfusat.
PCT/JP2019/027518 2018-07-12 2019-07-11 Système de circulation endoscopique de perfusat WO2020013281A1 (fr)

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Citations (8)

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Publication number Priority date Publication date Assignee Title
JPS62107843U (fr) * 1985-12-27 1987-07-09
JPH04161135A (ja) * 1990-10-26 1992-06-04 Olympus Optical Co Ltd 内視鏡装置
JPH1033582A (ja) * 1996-04-16 1998-02-10 Argomed Ltd 温度設定装置およびこの装置を用いた温度治療装置および方法
JP2009136380A (ja) * 2007-12-04 2009-06-25 Unitika Ltd 硬膜外腔冷却システム
JP2010022663A (ja) * 2008-07-22 2010-02-04 Olympus Medical Systems Corp 内視鏡洗浄消毒装置
JP2016530936A (ja) * 2013-08-21 2016-10-06 オリンパス ビンテル ウント イーベーエー ゲーエムベーハーＯｌｙｍｐｕｓ Ｗｉｎｔｅｒ ＆ Ｉｂｅ Ｇｅｓｅｌｌｓｃｈａｆｔ Ｍｉｔ Ｂｅｓｃｈｒａｎｋｔｅｒ Ｈａｆｔｕｎｇ 手術器具を洗浄するための方法および装置
JP2016540547A (ja) * 2013-10-28 2016-12-28 アイオジン， インコーポレイテッド 流体管理システム及び方法
WO2017208198A2 (fr) * 2016-06-01 2017-12-07 Neurosave, Inc. Système non invasif à usage unique et méthode de refroidissement sélectif du cerveau

Patent Citations (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS62107843U (fr) * 1985-12-27 1987-07-09
JPH04161135A (ja) * 1990-10-26 1992-06-04 Olympus Optical Co Ltd 内視鏡装置
JPH1033582A (ja) * 1996-04-16 1998-02-10 Argomed Ltd 温度設定装置およびこの装置を用いた温度治療装置および方法
JP2009136380A (ja) * 2007-12-04 2009-06-25 Unitika Ltd 硬膜外腔冷却システム
JP2010022663A (ja) * 2008-07-22 2010-02-04 Olympus Medical Systems Corp 内視鏡洗浄消毒装置
JP2016530936A (ja) * 2013-08-21 2016-10-06 オリンパス ビンテル ウント イーベーエー ゲーエムベーハーＯｌｙｍｐｕｓ Ｗｉｎｔｅｒ ＆ Ｉｂｅ Ｇｅｓｅｌｌｓｃｈａｆｔ Ｍｉｔ Ｂｅｓｃｈｒａｎｋｔｅｒ Ｈａｆｔｕｎｇ 手術器具を洗浄するための方法および装置
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