WO2019225876A1 - 약액주입장치에 사용되는 기체포집부재 및 이를 포함하는 약액주입장치 - Google Patents

약액주입장치에 사용되는 기체포집부재 및 이를 포함하는 약액주입장치 Download PDF

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Publication number
WO2019225876A1
WO2019225876A1 PCT/KR2019/005258 KR2019005258W WO2019225876A1 WO 2019225876 A1 WO2019225876 A1 WO 2019225876A1 KR 2019005258 W KR2019005258 W KR 2019005258W WO 2019225876 A1 WO2019225876 A1 WO 2019225876A1
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WO
WIPO (PCT)
Prior art keywords
gas
space
membrane
gas collecting
generating space
Prior art date
Application number
PCT/KR2019/005258
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English (en)
French (fr)
Korean (ko)
Inventor
김용현
Original Assignee
주식회사 이화메디텍
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by 주식회사 이화메디텍 filed Critical 주식회사 이화메디텍
Priority to CN201980033750.XA priority Critical patent/CN112153995B/zh
Publication of WO2019225876A1 publication Critical patent/WO2019225876A1/ko

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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
    • A61M5/178—Syringes
    • A61M5/20—Automatic syringes, e.g. with automatically actuated piston rod, with automatic needle injection, filling automatically
    • A61M5/2046—Media being expelled from injector by gas generation, e.g. explosive charge
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
    • A61M5/178—Syringes
    • A61M5/20—Automatic syringes, e.g. with automatically actuated piston rod, with automatic needle injection, filling automatically
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
    • A61M5/178—Syringes
    • A61M5/31—Details
    • A61M5/315—Pistons; Piston-rods; Guiding, blocking or restricting the movement of the rod or piston; Appliances on the rod for facilitating dosing ; Dosing mechanisms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
    • A61M5/178—Syringes
    • A61M5/31—Details
    • A61M5/315—Pistons; Piston-rods; Guiding, blocking or restricting the movement of the rod or piston; Appliances on the rod for facilitating dosing ; Dosing mechanisms
    • A61M5/31565—Administration mechanisms, i.e. constructional features, modes of administering a dose
    • A61M5/31576—Constructional features or modes of drive mechanisms for piston rods
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M2205/00—General characteristics of the apparatus
    • A61M2205/82—Internal energy supply devices
    • A61M2205/8218—Gas operated

Definitions

  • the present invention relates to a novel gas collecting member used in a gas generating chemical liquid injection device for injecting the chemical liquid by the gas pressure.
  • the present invention in the gas-generating chemical liquid injection device, the gas collecting member in the gas generating space is minimized the problem caused by being submerged in the liquid material used for gas generation, the gas generated in the gas generating space
  • the present invention relates to a technology that can stably and effectively collect and supply gas to a gas supply space.
  • the present invention also relates to a chemical liquid injection device including the gas collecting member as described above.
  • a medicine solution of a special injection medicine such as anticancer drugs, analgesics, antibiotics, etc.
  • a certain amount should be continuously added for a long time depending on the patient's condition. If a special injection drug is not continuously and consistently supplied to meet the required amount of the patient, it may cause a shock and an accident may occur.
  • a mechanical device for injecting a certain amount of chemical liquid per unit time has been devised and used.
  • Korean Patent Publication No. 10-0262930 discloses a drug injection device that can be carried by a patient.
  • This conventional portable chemical liquid injecting device has a structure in which a resilient bag of rubber material (called a balloon or a balloon) is provided in a chamber.
  • the elastic balloon has an inlet and an outlet. Inject the medicine into the inlet and the pouch will swell.
  • the chemical liquid is slowly drawn out through the outlet equipped with an elongated tube.
  • the drug solution is excreted in small amounts and injected into the patient's vein.
  • the chemical liquid injection device provided with such an elastic balloon
  • a defective product such as a non-uniform thickness or a fine hole may be produced during the production of the elastic balloon.
  • This failure results in a change in elasticity and the bag does not have the desired elasticity.
  • the elastic balloon may vary in elasticity according to the amount of the remaining chemical liquid, and thus the external force (elastic restoring force) affecting the flow of the chemical liquid may be different at the beginning and the end of the injection.
  • the chemical liquid injection device having an elastic balloon has a weak physical force to push the chemical liquid.
  • the chemical liquid injecting device having an elastic balloon having a low chemical liquid injection pressure is too sensitive to an external environment such as a height or a temperature of the device, and thus, the flow rate of the chemical liquid injected into the patient is very severe.
  • the flow rate of the chemical solution to be injected into the patient is large, if the chemical injection pressure is low, it may not be able to constantly push the chemical. For this reason, it is necessary to increase the chemical liquid injection pressure in the chemical liquid injection device.
  • higher pressure is required to change the flow rate from time to time while injecting the drug solution to the patient.
  • the gas-generating chemical injection device disclosed in Korea Patent Publication No. 10-0507593 is known.
  • the injection piston in the cylinder is moved slowly and stably by the generated high gas pressure, and the medicine liquid filled in the chemical storage space in the cylinder is stably and continuously injected into the patient at a constant flow rate by the forward movement of the injection piston. do.
  • the gas-generating chemical injection device generates a gas (carbon dioxide) by reacting a liquid material such as citric acid and a solid material such as sodium bicarbonate, and injects the chemical liquid by advancing the piston by using the pressure of the generated gas.
  • a gas carbon dioxide
  • the conventional gas-generating chemical liquid injection device disclosed in Korea Patent Publication No. 10-0507593 is a gas permeable-liquid impermeable membrane filter to collect only gas and supply gas to the gas supply space behind the injection piston. It includes a gas collecting member made. The gas collecting member is immersed in the liquid material used for gas generation in the gas generating space before and / or during use.
  • the gas collecting member is a gas permeable-liquid impermeable material
  • gas will not pass easily if it is immersed in a liquid material such as citric acid for a long time. That is, when the gas collecting member is immersed in the liquid material, there is no space for gas to pass through, and gas collecting is difficult. If the gas generated in the gas generating space is not collected by the gas collecting member well, the gas supply to the gas supply space is not smooth, and thus, the gas pressure pushing the rear of the piston is weakened or the rear of the piston is not pushed at a constant pressure. do.
  • the conventional gas-generating chemical liquid injection device as described above is an excellent technology, like the other excellent technology, the continuous improvement can be made.
  • the gas collecting member is immersed in the liquid substance used for gas generation in the gas generating space, and the problem generated is minimized, and the gas generated in the gas generating space is stably
  • the gas generated in the gas generating space is stably
  • the present invention minimizes the problem caused by the gas collecting member is attached only to the circumference of the body portion forming the gas generating space without contacting the bottom of the gas generating space is locked to the liquid material used for gas generation.
  • the present invention relates to a technology capable of stably and effectively collecting gas generated in a gas generating space and supplying it to a gas supply space.
  • An object of the present invention is to provide a novel gas collecting member used in the gas-generating chemical liquid injection device for injecting the chemical liquid by the gas pressure.
  • an object of the present invention is to minimize the problems caused by the gas trapping member is submerged in the liquid material used for gas generation in the gas generating space, in the gas generating chemical injection device, generated in the gas generating space It is to provide a technology for collecting the supplied gas stably and effectively to the gas supply space.
  • Another object of the present invention to provide a chemical liquid injection device comprising a gas collecting member as described above.
  • the gas collecting member provided in accordance with one embodiment of the present invention includes a gas generating space therein and is used in a chemical liquid injection device for injecting a chemical liquid by the gas pressure generated in the gas generating space.
  • a first membrane made of a material which passes gas generated in the gas generating space and does not pass the liquid substance used for gas generation;
  • a second membrane made of a material which is bonded to the first membrane to form a closed gas collecting space, and which does not pass gas generated in the gas generating space and a liquid material used for gas generation;
  • a gas collecting tube configured to connect the gas collecting space and the outside of the gas generating space (gas supply space) to guide the gas collected in the gas collecting space to the outside of the gas generating space (gas supply space).
  • the first membrane and the second membrane is formed into an elongate rectangle, the first membrane is disposed to surround the gas generating space, the second membrane is the gas It may be attached around the inner wall of the cylindrical body portion forming the generating space.
  • the gas collecting tube may be located at the end of the first membrane and the second membrane.
  • the gas collecting space has a narrow flow width of the gas toward the gas collecting tube in order to smoothly guide the gas collected therein to the gas collecting tube. That is, the length between the joining portion joining the first membrane and the second membrane becomes narrower on the gas collecting tube side.
  • the gas collecting member may be inserted into the gas generating space in an annular shape which is completely annular or partially open.
  • the first membrane is located inside the gas generating space
  • the second membrane is located outside the gas generating space, that is, the inner wall side of the body portion.
  • the first membrane made of a gas-permeable-liquid impermeable material is brought into contact with the gas generating space, and the second membrane made of a gas-impermeable-liquid impermeable material is attached around the inner wall of the body part, thereby Gas generated in the generating space can be more effectively collected.
  • the gas collecting member of an embodiment of the present invention can minimize the portion to be immersed in the liquid material used for gas generation by being inserted into the gas generating space in a ring shape, thereby stably and effectively collecting gas can do.
  • the present invention provides a chemical liquid injection device comprising a gas collecting member as described above.
  • the present invention in the gas-generating chemical liquid injection device, the gas collection member in the gas generating space can be minimized the problem caused by being immersed in the liquid material used for gas generation, gas
  • the gas generated in the generating space can be stably and effectively collected and supplied to the gas supply space.
  • FIG. 1 is a perspective view schematically showing a chemical liquid injection device according to an embodiment of the present invention.
  • Figure 2 is a perspective view of the chemical liquid injection device according to an embodiment of the present invention in a different direction.
  • Figure 3 is an exploded perspective view schematically showing a part of the gas collecting member and the chemical liquid injection device according to an embodiment of the present invention.
  • FIG. 4 is a view showing the gas collecting member in an unfolded state according to an embodiment of the present invention.
  • FIG. 5 is a cross-sectional view showing a main portion of the chemical liquid injection device according to an embodiment of the present invention cut in the longitudinal direction.
  • FIG. 6 is a partially enlarged cross-sectional view of FIG. 5.
  • FIG. 7 is a perspective view showing a shape (ring shape) when the gas collecting member according to one embodiment of the present invention is inserted into the gas generating space of the chemical liquid injection device.
  • FIG. 1 is a perspective view schematically showing a chemical injection device 1000 according to an embodiment of the present invention
  • Figure 2 is a perspective view of the chemical injection device 1000 according to an embodiment of the present invention from another direction
  • 3 is an exploded perspective view showing a part of the gas collecting member 200 and the chemical liquid injection device 1000 according to an embodiment of the present invention.
  • the chemical liquid injection device 1000 includes a substantially cylindrical cylinder 110, an injection piston 140, and a gas generator 130 as main components.
  • one end of the approximately cylindrical cylinder 110 is connected to the chemical liquid flow tube 150, the chemical liquid flows in and out, and the other end gas generation unit 130 is coupled.
  • the injection piston 140 is hermetically movable inside the cylinder 110, and the chemical liquid storage space 114 in which the chemical liquid is introduced and filled through the chemical liquid flow tube 150 inside the cylinder 110. And a gas supply space 116 to which gas generated in the gas generator 130 is supplied.
  • An end cap (not shown) may be provided at an end of the chemical liquid flow tube 150, and an injection needle or a catheter (not shown) may be connected to the end cap.
  • At least one groove is formed around the body of the injection piston 140, the sealing ring (144a, 144b) is fitted to each other is coupled.
  • the injection piston 140 may be hermetically moved inside the cylinder 110 by such sealing rings 144a and 144b.
  • the gas generator 130 is largely composed of a body 131 and a cap 132.
  • the substantially cylindrical body 131 forms a gas generating space 139 therein (see FIG. 5).
  • the gas generator 130 accommodates the liquid material L and the solid material 134.
  • the liquid material L is accommodated in the body 131 and the solid material 134 is received in the cap 132.
  • the solid material 134 is separated from the liquid material L by the partition wall 133 and accommodated in the cap 132.
  • the structure and shape of the partition wall 133 are not limited to those shown in FIG. 3, and the liquid material L and the solid material 134 are separated from each other, but are separated from the cap part 132 when an external force is applied to the cap part 132. Any structure can be used as long as the solid material 134 falls into the liquid material (L).
  • the solid material 134 may be configured, for example, in the form of pellets mainly composed of sodium bicarbonate, and the liquid material L may be an acidic liquid material such as citric acid which generates carbon dioxide upon reaction with the solid material 134. Can be.
  • the body 131 includes a liquid material injection hole 160 for injecting a liquid material L, such as citric acid.
  • the liquid material injection hole 160 is formed in a substantially cylindrical shape having a hollow portion therein and extends from the body portion 131 toward the gas supply space 116 (see FIGS. 1 to 3).
  • the liquid material injection hole 160 is connected to the gas generating space 139. The worker injects the liquid material L through the liquid material injection hole 160 into the gas generating space 139 and seals the liquid material injection hole 160 with a stopper or the like.
  • the generated gas is collected through the gas collecting member 200 in the body 131 and discharged to the gas supply space 116 of the cylinder 110, thereby pushing the rear of the injection piston 140.
  • the boss 137 protruding from the body portion 131 of the gas generator 130 may be provided with a pressure control valve 138 to prevent the pressure of the gas exceeds a predetermined pressure (Fig. 1 and Fig. 1). 2).
  • the pressure control valve 138 opens the gas supply space 116 to the outside (for example, the atmosphere) when the pressure of the gas supply space 116 is higher than the preset pressure to prevent the chemical liquid from being injected faster than the predetermined flow rate to the patient. It is connected to the gas out of the gas supply space 116 to the outside. As a result, the pressure of the gas supply space 116 is kept constant.
  • the switch member 136 is provided between the gas supply space 116 and the gas generating space 139, and connects the atmosphere and the gas supply space 116 when filling the chemical liquid, the gas supply space when the chemical liquid injection Connect 116 and the gas generating space (139).
  • the switch member 136 is provided between the atmosphere, the gas supply space 116 and the gas generating space 139. Connection here means connecting two or more spaces through which a gas (air or carbon dioxide) flows.
  • the atmosphere ( ⁇ () refers to the outside of the chemical liquid injection device 1000, the atmospheric pressure state. Of course, the present invention is not limited thereto, and the atmosphere may be a place or a device that maintains an atmospheric pressure or a similar pressure or maintains a pressure lower than the pressure of the chemical storage space 114 when the chemical liquid is injected.
  • the switch member 136 includes a switch cylinder 310, a switch piston 320, and a switch elastic member 330.
  • the switch cylinder 310 is connected to the atmosphere, the gas supply space 116 and the gas generating space 139.
  • the switch cylinder 310 may be a cylindrical cylinder extending in one direction.
  • the switch cylinder 310 may extend in the radial direction of the cylinder 110.
  • the shape and / or extension direction of the switch cylinder is not limited thereto.
  • the switch cylinder 310 may include a first hole 311 connecting the atmosphere and the inside of the switch cylinder 310, a second hole 312 connecting the gas generating space 139 and the inside of the switch cylinder 310.
  • the third hole 313 connects the gas supply space 116 to the inside of the switch cylinder 310.
  • the first hole 311, the second hole 312, and the third hole 313 serve as flow paths through which gas flows.
  • the third hole 313 is located between the first hole 311 and the second hole 312.
  • the third hole 313 may be formed closer to the first hole 311 than the second hole 312 based on the vertical direction (the longitudinal direction of the cylinder).
  • the second hole 312 and the third hole 313 are formed on the side wall of the switch cylinder 310 as shown in FIG.
  • the first hole 311 may be formed at one end of the switch cylinder 310 as shown in FIG. 5.
  • the third hole 313 is located between the second hole 312 and the first hole 311.
  • the distance between the first hole 311 and the third hole 313 is shorter than the distance between the first hole 311 and the second hole 312 with respect to the vertical direction (the longitudinal direction of the cylinder).
  • the other end of the switch cylinder 310 may be blocked.
  • the switch cylinder 310 may further include a fourth hole 314.
  • the fourth hole 314 is formed at the opposite side of the first hole 311, that is, at the other end of the switch cylinder 310.
  • the fourth hole 314 is blocked by the stopper 340.
  • the switch cylinder 310 as described above may be integrally formed on the body portion 131 of the gas generator 130.
  • the switch cylinder 310 may be configured separately and coupled to the body 131 of the gas generator 130.
  • the switch cylinder 310 will be described as a case where the body portion 131 is integrally formed, but is not limited thereto.
  • the trunk portion 131 of the gas generating unit 130 has partitions formed therein, and the outer wall thereof has a generally cylindrical shape.
  • the first hole 311, the second hole 312, the third hole 313, and the fourth hole 314 are formed in the inner partitions or the outer wall of the body 131.
  • the body portion 131 of the gas generator 130 may include an external air entrance 135 connected to the switch cylinder 310.
  • the external air entrance 135 is formed at the side of the body portion 131 of the gas generator 130 and is connected to the first hole 311 of the switch cylinder 310.
  • the outside air entrance 135 may be provided with a gas-permeable, liquid-impermeable hydrophobic filter (not shown). This hydrophobic filter allows external air to enter the device through the external air inlet 135, but blocks water, chemicals, liquid contaminants, etc. from entering the device from the outside.
  • the body 131 and the switch member 136 have been described in detail above.
  • the gas collecting member 200 collecting the gas generated in the gas generating space 139 and delivering the gas to the gas supply space 116 will be described in detail.
  • the gas collecting member 200 collects gas generated in the gas generating space 139 without passing the liquid material L and transfers the gas to the second hole 312.
  • the gas collecting member 200 includes a gas permeable-liquid impermeable material.
  • the gas collecting member 200 includes a first membrane 210, a second membrane 220, and a gas collecting tube 240.
  • the first membrane 210 is made of a material that does not pass the gas generated in the gas generating space 139 and does not pass the liquid material (L) used for gas generation, for example, a gas permeable-liquid impermeable filter. Can be done.
  • the second membrane 220 may be bonded to the first membrane 210 to form a sealed gas collecting space 250.
  • the second membrane 220 is made of a material that does not pass the gas generated in the gas generating space 139 and the liquid material (L) used for gas generation, for example, gas and liquid impermeable PVC ( Polyvinyl Chloride) material.
  • the material of the second membrane 220 is not limited thereto and may be made of various gas and liquid impermeable materials.
  • the first membrane 210 and the second membrane 220 have a substantially rectangular shape (rectangular shape), and the height (Z direction) thereof is approximately equal to or slightly higher than the inner height of the body portion 131.
  • the width (X direction) corresponds to the length of the inner wall circumference of the trunk portion 131. That is, the first membrane 210 and the second membrane 220 may surround the gas generating space 139 when inserted into the body portion 131.
  • the second membrane 220 may be bonded to the first membrane 210 to form a gas collection space 250.
  • the gas collection space 250 is a relatively narrow space before the gas is collected into the space between the first membrane 210 and the second membrane 220, but may be formed as shown in FIG. 5 when the gas is collected.
  • the second membrane 220 may be directly bonded to the first membrane 210 or indirectly through a medium.
  • edges of the first membrane 210 and the second membrane 220 may be bonded to each other to form a joint 230.
  • ultrasonic vibration may be applied along the edges of the first membrane 210 and the second membrane 220.
  • the bonding method is not limited thereto.
  • the first membrane 210 and the second membrane 220 have a substantially rectangular shape (rectangular shape), and edges are joined to form a gas collecting space 250 therein. Meanwhile, a nonwoven fabric or the like is further provided between the first membrane 210 and the second membrane 220 or in the gas collecting space 250, so that more efficient gas collecting is possible.
  • the gas collecting member 200 includes a gas collecting tube 240 connected to the gas collecting space 250 to discharge the gas collected in the gas collecting space 250.
  • the gas collecting tube 240 communicates the gas collecting space 250 and the gas supply space 116 and has a substantially thin tube shape.
  • the gas collection tube 240 is positioned between the first membrane 210 and the second membrane 220 and is in close contact with the first membrane 210 and the second membrane 220. That is, no gas leaks between the gas collecting tube 240 and the first membrane 210 and / or between the gas collecting tube 240 and the second membrane 220.
  • the gas collection tube 240 may be positioned at the ends of the first membrane 210 and the second membrane 220.
  • the gas collecting space 250 is narrowed toward the gas collecting tube 240 so that the flow width of the gas (Z direction) becomes narrower. That is, the distance between the upper and lower junctions 230 of the first membrane 210 and the second membrane 220 becomes narrower toward the gas collection tube 240.
  • the flow width of the gas or the length between the upper and lower junctions 230 may decrease rapidly, or may gradually decrease (see FIGS. 3, 4, and 7).
  • the gas collecting member 200 When the gas collecting member 200 is inserted into the body 131, the gas collecting member 200 may be inserted into a completely annular shape or an annular shape in which part thereof is opened (see FIGS. 3 and 7). In addition, the gas collecting member 200 may maintain an annular shape before insertion. At this time, the first membrane 210 is located inside, and the second membrane 220 is located outside. Therefore, the first membrane 210 made of a gas-permeable-liquid impermeable material is in contact with the gas generating space 139, whereby the gas collecting member 200 can collect the gas more effectively (see FIG. 5).
  • the gas collecting member 200 is located inside the trunk portion 131 in a ring shape, but has an annular inner wall circumference of the trunk portion 131. Is attached to.
  • the gas collecting member 200 is disposed to surround the gas generating space 139 so as to secure the gas generating space 139 as much as possible.
  • the gas collecting member 200 is not disposed on the bottom surface of the body portion 131 adjacent to the gas supply space 116.
  • the conventional gas collecting member has a bowl shape covering not only the inner wall of the body portion 131 but also the bottom surface of the body portion 131 adjacent to the gas supply space 116.
  • the conventional gas collecting member is exposed to and contacted with the liquid substance L while the liquid substance L is contained inside the body portion.
  • the conventional gas collecting member has a problem of being immersed in the liquid material (L) due to the repeated exposure and contact with the liquid material (L) even if made of a gas-permeable liquid impermeable material. When the gas collecting member is immersed in the liquid material (L) it is difficult to permeate the gas is difficult to perform the gas collection smoothly.
  • the gas collecting member 200 is stable by minimizing the portion to be immersed in the liquid material (L) by being inserted into the body portion 131 in a ring shape rather than a bowl shape. Effective gas collection is possible.
  • the gas collecting member 200 is connected to the second hole 312 as shown in Figure 5 and 6 to transfer the gas to the gas supply space 116. Since the gas collecting tube 240 is inserted in close contact with the second hole 312, the collected gas may be prevented from leaking.
  • the gas generated in the gas generating space 139 passes through the first membrane 210 located inside and moves to the gas collecting space 250.
  • the liquid material (L) is not introduced into the gas collection space 250 by the first membrane (210). Since gas is continuously introduced into and diffused into the gas collecting space 250, the internal pressure of the gas collecting space 250 is increased. As a result, the gas in the gas collecting space 250 is moved to the gas collecting tube 240.
  • the gas collected as described above moves from the gas collecting space 250 to the second hole 312 through the gas collecting tube 240.
  • the gas moved to the second hole 312 is introduced into the switch cylinder 310.
  • the gas introduced into the switch cylinder 310 raises the internal pressure of the switch cylinder 310 to move the switch piston 320 in the -X direction.
  • the second hole 312 and the third hole 313, which are blocked by the switch piston 320 are connected (see FIG. 6).
  • the gas introduced into the switch cylinder 310 moves to the gas supply space 116 through the third hole 313 to increase the internal pressure of the gas supply space 116.
  • the piston 140 moves forward as the internal pressure of the gas supply space 116 rises, and pushes the chemical liquid in the chemical storage space 114 to inject the chemical liquid.
  • the gas collecting member and the chemical liquid injection device including the same can minimize the problem that the gas collecting member is immersed in the liquid material, and stably and effectively collects the gas into the gas supply space. It can be supplied, thereby allowing smooth chemical injection.

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  • Health & Medical Sciences (AREA)
  • Vascular Medicine (AREA)
  • Engineering & Computer Science (AREA)
  • Anesthesiology (AREA)
  • Biomedical Technology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Hematology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Infusion, Injection, And Reservoir Apparatuses (AREA)
PCT/KR2019/005258 2018-05-24 2019-05-02 약액주입장치에 사용되는 기체포집부재 및 이를 포함하는 약액주입장치 WO2019225876A1 (ko)

Priority Applications (1)

Application Number Priority Date Filing Date Title
CN201980033750.XA CN112153995B (zh) 2018-05-24 2019-05-02 用于药液注入装置的气体捕集部件及包括其的药液注入装置

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
KR1020180058758A KR102018909B1 (ko) 2018-05-24 2018-05-24 약액주입장치에 사용되는 기체포집부재 및 이를 포함하는 약액주입장치
KR10-2018-0058758 2018-05-24

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WO2019225876A1 true WO2019225876A1 (ko) 2019-11-28

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KR (1) KR102018909B1 (zh)
CN (1) CN112153995B (zh)
TW (1) TW202003058A (zh)
WO (1) WO2019225876A1 (zh)

Citations (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
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