WO2019121962A1 - Procédé servant à fabriquer des crèmes de manière automatisée - Google Patents

Procédé servant à fabriquer des crèmes de manière automatisée Download PDF

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Publication number
WO2019121962A1
WO2019121962A1 PCT/EP2018/085911 EP2018085911W WO2019121962A1 WO 2019121962 A1 WO2019121962 A1 WO 2019121962A1 EP 2018085911 W EP2018085911 W EP 2018085911W WO 2019121962 A1 WO2019121962 A1 WO 2019121962A1
Authority
WO
WIPO (PCT)
Prior art keywords
production
container
individual
individualized
mixtures
Prior art date
Application number
PCT/EP2018/085911
Other languages
German (de)
English (en)
Inventor
Bernward Starke
Bernhard Mueller
Original Assignee
Delphi Salesconsulting Ag
Mworks Gmbh
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Delphi Salesconsulting Ag, Mworks Gmbh filed Critical Delphi Salesconsulting Ag
Publication of WO2019121962A1 publication Critical patent/WO2019121962A1/fr

Links

Classifications

    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B65—CONVEYING; PACKING; STORING; HANDLING THIN OR FILAMENTARY MATERIAL
    • B65B—MACHINES, APPARATUS OR DEVICES FOR, OR METHODS OF, PACKAGING ARTICLES OR MATERIALS; UNPACKING
    • B65B3/00—Packaging plastic material, semiliquids, liquids or mixed solids and liquids, in individual containers or receptacles, e.g. bags, sacks, boxes, cartons, cans, or jars
    • B65B3/26—Methods or devices for controlling the quantity of the material fed or filled
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01F—MIXING, e.g. DISSOLVING, EMULSIFYING OR DISPERSING
    • B01F33/00—Other mixers; Mixing plants; Combinations of mixers
    • B01F33/80—Mixing plants; Combinations of mixers
    • B01F33/85—Mixing plants with mixing receptacles or mixing tools that can be indexed into different working positions
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01F—MIXING, e.g. DISSOLVING, EMULSIFYING OR DISPERSING
    • B01F35/00—Accessories for mixers; Auxiliary operations or auxiliary devices; Parts or details of general application
    • B01F35/80—Forming a predetermined ratio of the substances to be mixed
    • B01F35/88—Forming a predetermined ratio of the substances to be mixed by feeding the materials batchwise
    • B01F35/881—Forming a predetermined ratio of the substances to be mixed by feeding the materials batchwise by weighing, e.g. with automatic discharge
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B65—CONVEYING; PACKING; STORING; HANDLING THIN OR FILAMENTARY MATERIAL
    • B65B—MACHINES, APPARATUS OR DEVICES FOR, OR METHODS OF, PACKAGING ARTICLES OR MATERIALS; UNPACKING
    • B65B3/00—Packaging plastic material, semiliquids, liquids or mixed solids and liquids, in individual containers or receptacles, e.g. bags, sacks, boxes, cartons, cans, or jars
    • B65B3/003—Filling medical containers such as ampoules, vials, syringes or the like
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01F—MIXING, e.g. DISSOLVING, EMULSIFYING OR DISPERSING
    • B01F2101/00—Mixing characterised by the nature of the mixed materials or by the application field
    • B01F2101/21—Mixing of ingredients for cosmetic or perfume compositions
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01F—MIXING, e.g. DISSOLVING, EMULSIFYING OR DISPERSING
    • B01F2101/00—Mixing characterised by the nature of the mixed materials or by the application field
    • B01F2101/22—Mixing of ingredients for pharmaceutical or medical compositions
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B65—CONVEYING; PACKING; STORING; HANDLING THIN OR FILAMENTARY MATERIAL
    • B65B—MACHINES, APPARATUS OR DEVICES FOR, OR METHODS OF, PACKAGING ARTICLES OR MATERIALS; UNPACKING
    • B65B2220/00—Specific aspects of the packaging operation
    • B65B2220/14—Adding more than one type of material or article to the same package

Definitions

  • the invention relates to a device for automated change of the composition of a batch, and a corresponding method.
  • the process according to the invention for the production of individualized mixtures for a pharmaceutical and / or cosmetics has four process steps.
  • First, an individual recipe for the production of a final product is read.
  • the individual formulation names at least the type and quantity of a plurality of individual components, the unit of the quantity is usually given in mass or volume.
  • the individual formulation or type and amount of a plurality of individual components is associated with a container that receives the final product.
  • the container and a dosing device are positioned relative to one another such that an individual component named in the individual formulation can be filled into the container by means of the dosing device.
  • an individual component named in the individual formulation is filled into the container by means of the metering device.
  • method steps three and four are repeated for the subsequent individualized mixture.
  • Several containers and / or metering devices are positioned simultaneously with each other. In the positioning of the containers and / or the positioning of the metering devices, the containers and / or the metering devices are moved individually. Under the individual movement of the containers and / or metering devices is understood in the context of this invention, a movement that regardless of the movement of the other containers and / or dosing. Thus, one container may be being moved while another container is being filled, or in one container the positioning operation is being started while the positioning process of another container is being completed.
  • the respective container to be moved is moved relative to another container and / or the respective dosing device to be moved relative to another dosing device. This allows an economic execution of the filling process, as this allows the containers to be positioned only to those metering devices, which also has a component of the individual recipe associated with the container.
  • both the container and the metering device will be moved during the positioning of a container to a metering device. This has the advantage that the workflows during the filling of the containers individually designed and the efficiency of the filling machine can be significantly increased.
  • the container (4) are filled individually.
  • a container is filled while another container is positioned, for example, or that in a container, the filling process is just started while the filling process of another container is just completed.
  • the movement and / or the filling of the containers is optional. That is, both the containers along the product lines and the metering devices along the component lines can be moved randomly.
  • the type and quantity of basic components are read in as the individual formulation is read.
  • a cream typically contains a plurality of basic components that are the same for each cream, eg, glycerine.
  • the active ingredients of the cream vary depending on the purpose.
  • the type and amount of the base components of the cream are selected such that the cream prepared according to the individual formulation has a viscosity in a predetermined range of 10 to 250,000 mPas, preferably 100 to 100,000 mPas and particularly preferably 1,000 to 25,000 mPas. Due to this viscosity of the cream, thorough mixing of the individual components and the base components during a standardized mixing process after filling the container is ensured.
  • the order of addition of the individual components is determined from the individual formulation. To avoid the formation of inhomogeneities or reactions of the individual components with each other, in some cases a certain order of addition of the individual components must be taken into account. If this is not the case, reduced stability of the mixtures, reactions of individual components and consequently undesired reaction products and / or precipitation of individual components may occur. Furthermore, the temperatures at which certain individual components must be added may be different and thus make a certain order production-wise or make economic sense.
  • Stability is an important quality feature for medicines and creams. This applies to the same extent for medicines individually prepared in the formulation for internal or external purposes or creams. A drug is then called stable, if its important properties do not change for a reasonable amount of time or only to an acceptable extent. The stability should therefore be met for at least 1 week, preferably 1 month and more preferably 6 months. In creams, the time requirements are much longer and are developed, tested and determined during product development. In terms of stability or instability, a distinction is made between chemical, physical, microbiological and photo instability.
  • the container is filled with basic components.
  • the container can be filled with individual components with the basic components before, during or after filling of the container.
  • the filling of the containers with base components takes place in a different production area than the filling of the containers with individual components.
  • the containers can be filled with basic components by known filling methods, e.g. also by external suppliers.
  • the filling of the containers with individual components takes place by means of the method according to the invention.
  • a control command is generated in a control unit.
  • the control command is formed from the quantity of an individual component read in the individual recipe.
  • the control command thus also contains the type and quantity of the individual components of a read-in individual recipe of a mixture that has been read into the control unit.
  • the control command is suitable for controlling a dosing device. About the metering a named in the individual recipe Individual component is filled in the container.
  • control command includes a command for positioning the metering device.
  • the control command positions the metering device on the container, which is to be filled with the corresponding individual component.
  • control command contains a command for dispensing the previously read into the control unit amount of the individual component of the metering device.
  • the container is filled via the metering device with the amount of the individual component of the mixture.
  • control command generated in a control unit includes a command for positioning the container into which the mixture is filled.
  • the container is positioned to exactly the metering device with which the container is to be filled with the individual component of the mixture.
  • the metering device is controlled so that the metering device emits the read amount of the individual component in the container. This design ensures that exactly the container is filled with the correct type and amount of the individual component of the mixture, which was previously read into the control unit.
  • the components which have been filled into the container via the metering device are mixed together.
  • the mixture contains basic components that are in another production area in the container were filled, and individual components that were filled with the inventive method in the container. All components are mixed after filling with all components or after filling with an individual component via eg a mixer in a homogeneous mixture.
  • the production area for filling the containers with individual components has a plurality of product lines, which are arranged parallel to one another. On these product lines, a plurality of containers are positioned to the metering devices. Due to this advantageous embodiment, the filling of the containers per unit time is significantly increased, the production costs are low for each individualized mixture produced.
  • the substantially equal product lines allow a high degree of serviceability of the production area, the risk of a total failure in a defective product line is low. Due to the modular design of the production area can be easily extended according to the number of containers to be filled.
  • a plurality of metering devices for filling the containers with individual components is positioned parallel to a plurality of the product lines.
  • each container can be filled with a plurality of individual components via the metering devices.
  • This embodiment of the invention increases the production of individualized mixtures per unit time and thus reduces manufacturing costs. Number and type of metering devices can also be easily and inexpensively changed depending on the purpose of the mixture.
  • a plurality of containers along a plurality of mutually parallel product lines to a plurality positioned by metering devices Due to this advantageous embodiment, the filling of the containers per unit time is significantly increased, the production costs are low for each individualized mixture produced. The ease of maintenance, redundancy of the components of the production area and thus its resilience is high. Due to the modular design of the production area can be easily extended according to the number of containers to be filled.
  • the method according to the invention comprises the creation of a first data packet.
  • This first data packet contains data for the notification of the end product and serves to identify a mixture to be filled into a container.
  • the first data packet is used to compare the quantity and composition of a ordered mixture with an already prepared mixture. This ensures accurate monitoring of the production process at all times.
  • a primary key on the container refers to this data packet stored in a central database.
  • the first data packet is output.
  • the output of the first data packet serves the control unit to identify a mixture to be filled into a container and already filled. This ensures constant monitoring and quality assurance of production.
  • the output of the first data packet takes place electronically.
  • the first data packet is stored, for example, on an RFID chip, which is connected to the container by means of suitable devices for orientation and support in the transport systems of the production area.
  • the output of the first data packet can also be done on a screen to allow an operator to monitor and document the production process at any time.
  • a second data packet is created. This second data packet contains data for the labeling of the final product and data on the composition of the mixture, product name and other data that are important for the end user.
  • the second data packet is output.
  • the data of the second data packet issuing the data of the second data packet to the end user e.g. made accessible via an app and / or in print.
  • the output of the second data packet takes place on a printer.
  • the printed form of the second data packet is affixed to the container, usually glued, e.g. as a QR code.
  • the customer has the option to order the identical formula at a later date via a smartphone app by scanning the QR code on the bottom of a container.
  • the process steps for the production of a second mixture are repeated. This includes at least the method steps reading an individual recipe for the production of the second mixture, assignment of the individual formulation or the type and quantity of a plurality of individual components to a container, positioning the container and a dosing device for an individual component named in the individual formulation each other and filling the container with one of the individual components named in the individual recipe.
  • the individual formulation of the first mixture is different from the individual formulation of the second mixture.
  • the change from the production of the first mixture for the production of the second mixture is fully automated. The change in production from a first individual recipe to one other second individual recipe is carried out without further intervention in the production process from the outside, for example by entering a command.
  • FIG. 1 flowchart of the inventive method for the production of individualized mixtures
  • FIG. 2 shows a flow chart of the method according to the invention for the production of individualized mixtures with control commands and mixing of the components.
  • FIG. 3 Flowchart of the method according to the invention for the production of individualized mixtures
  • FIG. 5 shows a view of a production area for the preparation of creams.
  • FIG. 6 shows a view of a container for receiving a pharmaceutical or
  • the method 1 according to the invention for the production of individualized mixtures 2 for a pharmaceutical and / or cosmetics has four method steps (FIG. 1).
  • First, the recipe for the production of the final product is read in 100.
  • the individual formulation names at least the type and quantity of a plurality of individual components, the unit of the amount is usually in bulk or volume specified.
  • the individual formulation or type and quantity of a plurality of individual components is associated with a container 4, which receives the end product.
  • the container 4 and a metering device 6 are positioned relative to one another such that the container 4 can be filled by means of the metering device 6, an individual component named in the individual formulation.
  • the fourth method step 300 the container 4 and a metering device 6 are positioned relative to one another such that the container 4 can be filled by means of the metering device 6, an individual component named in the individual formulation.
  • Process step 400 is filled into the container 4 by means of the dosing device 6, an individual component named in the individual formulation.
  • the method steps three 300 and four 400 are repeated for the individualized mixture 2 until all individual components of the formulation are filled in the container 4, the method 1 is thus completed.
  • a plurality of containers 4 and metering devices 6 are positioned relative to one another, with the containers 4 being moved individually during the positioning of the containers 4.
  • Dosing devices 6 are moved individually. In particular, by the possibility of random movement of the metering devices 6 on the component sections 5 and the containers 4 on the product lines 3, the filling can be operated efficiently. Furthermore, a high degree of redundancy against product line 3 failure is achieved by this method. It can be flexibly adapted to the number of individual components and flexibly to the needs (container / time). Due to this method 1, it is possible to manufacture in particular individualized formulations. The individual recipes are combined in the container 4 and stored. Sequence, proportion and number of different components can be adjusted within wide limits depending on the type of product. Different products can be realized by the method 1 according to the invention, for example mixing a liquid, paste or powder of different active ingredients, for example creams or oils.
  • a cream typically contains a plurality of basic components that are the same for each cream, eg, glycerine. These basic components account for the largest amount of a cream in terms of quantity and essentially determine their viscosity.
  • the base components are selected in the process 1 according to the invention such that the viscosity of the cream as the end product is in the range from 1000 to 25,000 mPas.
  • the active ingredients of a cream vary depending on the purpose. Therefore, during the first process step, the type and quantity of the basic components are read in as well.
  • the base components themselves are usually filled in the container 4 before the individual components, as well as the base components can be filled after filling with the individual components in the container.
  • FIG. 2 shows the schematic sequence of the method 1 according to the invention using control commands.
  • the individual recipe for the production of the final product is read.
  • the individual formulation is assigned to a container 4.
  • a control command for positioning the container 250 is generated in the control unit 8.
  • the container 4 is positioned so that the individual components can be filled into the container 4 by means of a metering device 6. During the positioning of a container 4, the container 4 is moved relative to another container 4. Alternatively, while positioning a
  • Dosing devices 6, the metering device 6 are moved relative to another metering device 6.
  • a control command for dispensing a specific quantity specified in the individual formulation is generated in the control unit 8.
  • the metering device 6 is activated.
  • the seventh method step 400 is by means of the metering device 6 the
  • step 500 Individual component filled in the container 4. At the same time several containers 4 can be filled. In order to fill several different individual components in one and the same container 4, steps three to seven are repeated until all the individual components specified in the individual formulation have been filled into the container 4.
  • the components for example a mixer, are mixed in the filled container 4. during the positioning of a container (4) to a metering device (6) both the container (4) and the metering device (6) are moved.
  • FIG. 3 shows the sequence of the method 1 according to the invention using data packets.
  • the recipe for the production of the final product is read.
  • the individual formulation is assigned to a container 4.
  • the container 4 is positioned so that the individual component can be filled into the container 4 by means of a metering device 6. During the positioning of a container 4 to a metering device 6, both the container 4 and the metering device 6 are moved.
  • an individual component named in the individual formulation is filled into the container 4 by means of the metering device 6. Parallel to the filling of a container 4 more containers can be filled.
  • the filling of the containers (4) takes place individually with regard to the quantity, the duration and / or the time of filling.
  • a first data packet is generated, which contains data for the notification of the end product.
  • the first data package contains the recipe, container type identification and customer data and is stored permanently in a database together with the production data and the recipe.
  • the first data packet is output and stored, for example, on an RFID chip which is connected to the container 4 by means of suitable devices for orientation and mounting in the transport systems of the production area connected is. The first data packet is queried by an RFID scanner.
  • a second data packet is generated, which contains data for the labeling of the final product and data about the composition of the mixture 2, product name and customer data.
  • the second data packet is output and, for example, attached to the container 4 as a QR code.
  • the customer has the option of ordering the identical formula at a later time via, for example, a smartphone app by scanning the QR code on the underside of the container 4.
  • FIG. 4 shows the communication paths and directions of the method 1 according to the invention.
  • the recipe for the individualized mixture 2 is read into the central control unit 8 for the method 1.
  • the control unit 8 generates a control command 250 to the product line 3 to deliver the container 4 along the product line 3 to position the dosing device 6 so that the individual component can be filled into the container 4 by means of the metering device 6. If the positioning of the container 4 is carried out, the product section 3 sends a corresponding signal to the control unit 8.
  • the control unit 8 generates a control command 350 to the metering device 6, which is positioned on the container 4 and by a second control command of the control unit 8, the container. 4 filled with the individual component. Once this has been done, the metering device 6 sends a corresponding signal to the control unit 8.
  • the process of positioning the container 4, positioning the metering device 6 and filling the container 4 is repeated until all individual components of the formula read into the control unit 8 have been filled into the container 4.
  • the control unit 8 sends control commands 250, 350 to product lines 3 and metering devices 6 and receives feedback from them on the execution carried out.
  • the control unit 8 also sends data packets 600, 800 to the output unit 9.
  • the output unit 9 stores and outputs data on recipe, Container identification as well as customer data. The output takes place, for example, on an RFID chip, which is connected to the container 4, and as a QR code on the container 4.
  • Fig. 5 shows a production area for the preparation of creams.
  • the inventive method 1 begins by the containers 4 are placed in the adapter loading station 19 in each case an adapter 18.
  • the adapter 18 has a unique adapter ID that can be read by the RFID chip mounted on it.
  • the recipe ID, container type ID and adapter ID are linked to the data for the duration of production.
  • the containers 4 are fed through the feed section 15 to the production area and over buffer sections 16 in front of the product axes.
  • the buffer section 16 stores some adapters 18 in order to avoid waiting times of the product axes or jams in the feed section 15.
  • a plurality of component sections 5 are arranged substantially perpendicular to the product sections 3.
  • Dosing device 6 is arranged or positionable in a node 7 of a component section 5 with a product section 3.
  • the nodes 7 are arranged in the form of an nxm matrix.
  • the containers 4 are introduced from the feed line 15 in the product axes.
  • the product axes position the containers 4 according to the recipe under the dosing axes.
  • the metering axes position the metering devices 6 above the containers 4 and meter the programmed amount of the individual components into the containers 4 until all components are filled in accordance with the recipe. Thereafter, the containers 4 are introduced from the product axes in the discharge path 22. At the end of the process 1, the containers 4 are taken out of the adapters 18 in the adapter unloading station 20.
  • a container 4 for receiving the base and individual components is shown in Fig. 6.
  • container 4 the cream is mixed and delivered to the end customer. Size and shape of the containers 4 can be chosen essentially freely.
  • the bottle 4, flask and pump dispenser, etc. are conceivable.
  • the container 4 has an anti-rotation device 24, for example a groove, in order to be secured against rotation in the adapter 18.
  • Each container 4 receives on the bottom a unique label. In this embodiment, it is a QR code 23 printed and is so clearly identifiable.
  • the QR code 23 contains the recipe ID, container type ID and / or set ID. This QR code 23 is permanently stored in a database together with the manufacturing data and the composition of the batch 2. This ensures a clear manufacturing control and consistent quality assurance. Repeat orders can be conveniently triggered by the customer through, for example, a smartphone app.
  • a unique-unique primary key can be noted, which uniquely indexes the record with customer data, recipe and production instructions in the database.

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  • Engineering & Computer Science (AREA)
  • Mechanical Engineering (AREA)
  • Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Basic Packing Technique (AREA)

Abstract

L'invention concerne un procédé pour la fabrication de mixtures personnalisées pour un produit pharmaceutique et/ou un produit cosmétique. Le procédé comprend les étapes consistant à : lire (100) une ordonnance personnalisée pour la fabrication d'un produit final ; associer (200) l'ordonnance personnalisée ou le type et la quantité d'une multitude de composants individuels à un récipient ; positionner (300) le récipient et un dispositif de dosage pour un composant individuel connu dans l'ordonnance personnalisée l'un par rapport à l'autre ; et remplir (400) le récipient avec un composant individuel désigné dans l'ordonnance personnalisée. L'ordonnance personnalisée désigne au moins le type et le poids ou volume d'une multitude de composants individuels.
PCT/EP2018/085911 2017-12-20 2018-12-19 Procédé servant à fabriquer des crèmes de manière automatisée WO2019121962A1 (fr)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DE102017130737.0 2017-12-20
DE102017130737.0A DE102017130737A1 (de) 2017-12-20 2017-12-20 Verfahren zur automatisierten Herstellung von Cremes

Publications (1)

Publication Number Publication Date
WO2019121962A1 true WO2019121962A1 (fr) 2019-06-27

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Application Number Title Priority Date Filing Date
PCT/EP2018/085911 WO2019121962A1 (fr) 2017-12-20 2018-12-19 Procédé servant à fabriquer des crèmes de manière automatisée

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WO (1) WO2019121962A1 (fr)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN113262716A (zh) * 2021-05-27 2021-08-17 常州华青自动化系统有限公司 一种多组分称重式智能配料系统

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Publication number Priority date Publication date Assignee Title
US4525071A (en) * 1984-05-31 1985-06-25 Crawford & Russell, Inc. Additive inventory control, batching and delivery system
US5903465A (en) 1993-08-23 1999-05-11 Elizabeth Arden Company Method and apparatus for customizing cosmetic products
DE19909896A1 (de) * 1999-03-06 2000-09-14 Stefan Soine Verfahren und Vorrichtung zum Herstellen eines Gemischs aus Ausgangsstoffen
WO2001075586A1 (fr) 2000-03-31 2001-10-11 Imx Labs, Inc. Systeme et procede de selection de la couleur d'un vernis a ongles
US20020056724A1 (en) 2000-08-25 2002-05-16 Manzari Kenneth Paul Apparatus suitable for preparing a custom personal care composition
EP3085437A1 (fr) * 2015-04-20 2016-10-26 INKMAKER S.r.l. Système et procédé de distribution de fluides, en particulier de fluides colorés

Family Cites Families (1)

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Publication number Priority date Publication date Assignee Title
DE102004020510B4 (de) * 2004-04-26 2007-11-29 Edwin Kohl Anlage zur Bestückung von Verpackungseinheiten mit dem verordnungsgemäßen Wochenbedarf von Patienten entsprechenden Medikamenten

Patent Citations (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4525071A (en) * 1984-05-31 1985-06-25 Crawford & Russell, Inc. Additive inventory control, batching and delivery system
US5903465A (en) 1993-08-23 1999-05-11 Elizabeth Arden Company Method and apparatus for customizing cosmetic products
DE19909896A1 (de) * 1999-03-06 2000-09-14 Stefan Soine Verfahren und Vorrichtung zum Herstellen eines Gemischs aus Ausgangsstoffen
WO2001075586A1 (fr) 2000-03-31 2001-10-11 Imx Labs, Inc. Systeme et procede de selection de la couleur d'un vernis a ongles
US20020056724A1 (en) 2000-08-25 2002-05-16 Manzari Kenneth Paul Apparatus suitable for preparing a custom personal care composition
EP3085437A1 (fr) * 2015-04-20 2016-10-26 INKMAKER S.r.l. Système et procédé de distribution de fluides, en particulier de fluides colorés

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN113262716A (zh) * 2021-05-27 2021-08-17 常州华青自动化系统有限公司 一种多组分称重式智能配料系统

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