WO2019066252A3 - 무궁화 추출물을 포함하는 미세먼지에 의한 피부 세포 손상 케어용 또는 항균성 펩티드 저해용 조성물 - Google Patents
무궁화 추출물을 포함하는 미세먼지에 의한 피부 세포 손상 케어용 또는 항균성 펩티드 저해용 조성물 Download PDFInfo
- Publication number
- WO2019066252A3 WO2019066252A3 PCT/KR2018/009516 KR2018009516W WO2019066252A3 WO 2019066252 A3 WO2019066252 A3 WO 2019066252A3 KR 2018009516 W KR2018009516 W KR 2018009516W WO 2019066252 A3 WO2019066252 A3 WO 2019066252A3
- Authority
- WO
- WIPO (PCT)
- Prior art keywords
- fine dust
- antibacterial peptide
- composition
- cell damage
- expression
- Prior art date
Links
- 239000003910 polypeptide antibiotic agent Substances 0.000 title abstract 5
- 230000002401 inhibitory effect Effects 0.000 title abstract 3
- 210000004927 skin cell Anatomy 0.000 title abstract 3
- 244000130592 Hibiscus syriacus Species 0.000 title abstract 2
- 235000018081 Hibiscus syriacus Nutrition 0.000 title abstract 2
- 230000005779 cell damage Effects 0.000 title abstract 2
- 208000037887 cell injury Diseases 0.000 title abstract 2
- 230000014509 gene expression Effects 0.000 abstract 5
- 239000000428 dust Substances 0.000 abstract 2
- 230000001105 regulatory effect Effects 0.000 abstract 2
- 230000037380 skin damage Effects 0.000 abstract 2
- 102000010907 Cyclooxygenase 2 Human genes 0.000 abstract 1
- 108010037462 Cyclooxygenase 2 Proteins 0.000 abstract 1
- 239000004615 ingredient Substances 0.000 abstract 1
- 108090000623 proteins and genes Proteins 0.000 abstract 1
Classifications
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- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23L—FOODS, FOODSTUFFS, OR NON-ALCOHOLIC BEVERAGES, NOT COVERED BY SUBCLASSES A21D OR A23B-A23J; THEIR PREPARATION OR TREATMENT, e.g. COOKING, MODIFICATION OF NUTRITIVE QUALITIES, PHYSICAL TREATMENT; PRESERVATION OF FOODS OR FOODSTUFFS, IN GENERAL
- A23L33/00—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof
- A23L33/10—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof using additives
- A23L33/105—Plant extracts, their artificial duplicates or their derivatives
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/96—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution
- A61K8/97—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution from algae, fungi, lichens or plants; from derivatives thereof
- A61K8/9783—Angiosperms [Magnoliophyta]
- A61K8/9789—Magnoliopsida [dicotyledons]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q19/00—Preparations for care of the skin
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23V—INDEXING SCHEME RELATING TO FOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES AND LACTIC OR PROPIONIC ACID BACTERIA USED IN FOODSTUFFS OR FOOD PREPARATION
- A23V2002/00—Food compositions, function of food ingredients or processes for food or foodstuffs
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Veterinary Medicine (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Natural Medicines & Medicinal Plants (AREA)
- Engineering & Computer Science (AREA)
- Botany (AREA)
- Mycology (AREA)
- Biotechnology (AREA)
- Microbiology (AREA)
- Chemical & Material Sciences (AREA)
- Epidemiology (AREA)
- Birds (AREA)
- Dermatology (AREA)
- Alternative & Traditional Medicine (AREA)
- Medical Informatics (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Nutrition Science (AREA)
- Food Science & Technology (AREA)
- Polymers & Plastics (AREA)
- Cosmetics (AREA)
- Medicines Containing Plant Substances (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Abstract
본 명세서에는 무궁화 추출물을 유효성분으로 포함하는 조성물로서, 미세먼지에 의해 발현량이 영향을 받는 피부 세포 내 유전자인 IL-36G(NM_019618), PTGS2(NM_000963), XDH(NM_000379) 및 S100A7(NM_002963)로 이루어진 군에서 선택되는 하나 이상의 발현량을 정상 수준으로 조절하는 미세먼지에 의한 피부 손상 케어용 조성물 및 항균 펩티드인 S100A7(NM_002963)의 발현량을 정상 수준으로 조절하는 항균성 펩티드 저해용 조성물이 개시된다. 상기 미세먼지에 의한 피부 손상 케어용 조성물 및 항균성 펩티드 저해용 조성물을 이용함으로써, 미세먼지에 의해 변화되는 유전자 발현량을 정상 수준으로 되돌려 피부 세포의 손상을 케어할 수 있고, 다양한 원인에 의하여 증가한 항균성 펩티드의 발현량을 정상 수준으로 되돌릴 수 있다.
Priority Applications (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
SG11202002808QA SG11202002808QA (en) | 2017-09-29 | 2018-08-20 | Composition for treating fine dust-caused skin cell damage or for inhibiting antimicrobial peptide, comprising hibiscus syriacus extract |
US16/651,880 US11433110B2 (en) | 2017-09-29 | 2018-08-20 | Composition for treating fine dust-caused skin cell damage or for inhibiting antimicrobial peptide, comprising Hibiscus syriacus extract |
CN201880077667.8A CN111432798A (zh) | 2017-09-29 | 2018-08-20 | 包含木槿花提取物的用于护理由微尘引起的皮肤细胞损伤或用于抑制抗菌肽的组合物 |
Applications Claiming Priority (4)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
KR10-2017-0127667 | 2017-09-29 | ||
KR1020170127665A KR102087189B1 (ko) | 2017-09-29 | 2017-09-29 | 무궁화 추출물을 포함하는 항균성 펩티드 저해용 조성물 |
KR10-2017-0127665 | 2017-09-29 | ||
KR1020170127667A KR102090133B1 (ko) | 2017-09-29 | 2017-09-29 | 무궁화 추출물을 포함하는 미세먼지에 의한 피부 세포 손상 케어용 조성물 |
Publications (2)
Publication Number | Publication Date |
---|---|
WO2019066252A2 WO2019066252A2 (ko) | 2019-04-04 |
WO2019066252A3 true WO2019066252A3 (ko) | 2019-05-16 |
Family
ID=65901567
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
PCT/KR2018/009516 WO2019066252A2 (ko) | 2017-09-29 | 2018-08-20 | 무궁화 추출물을 포함하는 미세먼지에 의한 피부 세포 손상 케어용 또는 항균성 펩티드 저해용 조성물 |
Country Status (4)
Country | Link |
---|---|
US (1) | US11433110B2 (ko) |
CN (1) | CN111432798A (ko) |
SG (1) | SG11202002808QA (ko) |
WO (1) | WO2019066252A2 (ko) |
Citations (4)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
KR20100080164A (ko) * | 2008-12-31 | 2010-07-08 | 한국생명공학연구원 | (―)―압토시몬을 유효성분으로 포함하는 염증질환 예방 또는 치료용 약학적 조성물 |
KR100985719B1 (ko) * | 2009-09-15 | 2010-10-06 | (주)지에프씨 | 노나무와 무궁화 추출물을 유효성분으로 하는 화장료 조성물 |
KR101629706B1 (ko) * | 2015-09-08 | 2016-06-13 | (주)셀트리온 | 황사와 미세먼지에 의해 유발된 염증을 완화시키는 천연식물 추출물을 포함하는 조성물 |
KR20170024267A (ko) * | 2015-08-25 | 2017-03-07 | 호서대학교 산학협력단 | 무궁화의 꽃으로부터 추출된 정유를 포함하는 피부 재생용 외용제 및 화장료 조성물 |
Family Cites Families (8)
Publication number | Priority date | Publication date | Assignee | Title |
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JPH0477432A (ja) * | 1990-07-18 | 1992-03-11 | Koushindou:Kk | 汗疱状白癬等の皮膚病用薬剤及びその製法 |
KR100383379B1 (ko) * | 2000-11-24 | 2003-05-12 | (주) 바임래버러토리즈 | 무궁화 원료 추출 방법 |
JP2003171300A (ja) | 2001-09-28 | 2003-06-17 | Kobayashi Pharmaceut Co Ltd | メラニン生成抑制剤 |
JP2007119432A (ja) | 2005-10-31 | 2007-05-17 | Ichimaru Pharcos Co Ltd | ペルオキシソーム増殖剤応答性受容体活性化剤 |
KR20100059302A (ko) | 2008-11-26 | 2010-06-04 | (주)아모레퍼시픽 | 목근피 추출물 함유 피부외용제 조성물 |
AU2011325867B2 (en) | 2010-11-03 | 2015-11-12 | Cimtech Pty Limited | Methods and compositions for maintaining and improving the health of skin |
KR20190089098A (ko) | 2011-04-06 | 2019-07-29 | 마리 케이 인코포레이티드 | 식물 추출물을 포함하는 국소 스킨 케어 제형 |
KR101490762B1 (ko) | 2013-06-25 | 2015-02-11 | 주식회사 코리아나화장품 | 오크라 다당체를 유효성분으로 함유하는 화장료 조성물 |
-
2018
- 2018-08-20 WO PCT/KR2018/009516 patent/WO2019066252A2/ko active Application Filing
- 2018-08-20 SG SG11202002808QA patent/SG11202002808QA/en unknown
- 2018-08-20 CN CN201880077667.8A patent/CN111432798A/zh active Pending
- 2018-08-20 US US16/651,880 patent/US11433110B2/en active Active
Patent Citations (4)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
KR20100080164A (ko) * | 2008-12-31 | 2010-07-08 | 한국생명공학연구원 | (―)―압토시몬을 유효성분으로 포함하는 염증질환 예방 또는 치료용 약학적 조성물 |
KR100985719B1 (ko) * | 2009-09-15 | 2010-10-06 | (주)지에프씨 | 노나무와 무궁화 추출물을 유효성분으로 하는 화장료 조성물 |
KR20170024267A (ko) * | 2015-08-25 | 2017-03-07 | 호서대학교 산학협력단 | 무궁화의 꽃으로부터 추출된 정유를 포함하는 피부 재생용 외용제 및 화장료 조성물 |
KR101629706B1 (ko) * | 2015-09-08 | 2016-06-13 | (주)셀트리온 | 황사와 미세먼지에 의해 유발된 염증을 완화시키는 천연식물 추출물을 포함하는 조성물 |
Non-Patent Citations (1)
Title |
---|
JANG, AH RAM: "Study on cosmetic physiological and skin cell activity of Hibiscus Syriacus extracts", MASTER'S THESIS, DEPT. OF GRADUATE SCHOOL OF SOCIAL CULTURE, 2012, Hannam University, pages 8 - 29 * |
Also Published As
Publication number | Publication date |
---|---|
SG11202002808QA (en) | 2020-04-29 |
US11433110B2 (en) | 2022-09-06 |
CN111432798A (zh) | 2020-07-17 |
WO2019066252A2 (ko) | 2019-04-04 |
US20200230186A1 (en) | 2020-07-23 |
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