Classifications

• • A—HUMAN NECESSITIES
  • A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
  • A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
  • A01N43/00—Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds
  • A01N43/90—Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds having two or more relevant hetero rings, condensed among themselves or with a common carbocyclic ring system
• • A—HUMAN NECESSITIES
  • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
  • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
  • A61P33/00—Antiparasitic agents
• • C—CHEMISTRY; METALLURGY
  • C07—ORGANIC CHEMISTRY
  • C07D—HETEROCYCLIC COMPOUNDS
  • C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
  • C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
  • C07D471/04—Ortho-condensed systems

Definitions

• haloalkylsulfinyl C1--C4 haloalkylsulfonyl, Cv-C 4 alkylamino, C 2 -Cg dialkylamino, C 3 -Cg cycloalkylamino, C2-C4 alkoxyalkyl, C2-C4
• halocycloalkyl haloalkoxy
• haloalkylthio haloalkenyl
• haloalkyl examples include CF 3 0-, CCI3CH2O-, HCF 2 CH 2 CH 2 0- and CF 3 CH 2 0-.
• haloalkylthio examples include CCI3S-, CF3S-, CCI3CH2S- and C1CH 2 CH 2 CH 2 S-.
• a "ring” or “ring system” as a component of Formula 1 is carbocyclic or heterocyclic.
• the term “ring system” denotes two or more fused rings.
• the terms "bicyclic ring system” and “fused bicyclic ring system” denote a ring system consisting of two fused rings, which can be “ortho-fused", “bridged bicyclic” or “spiro bicyclic”.
• An "ortho-fused bicyclic ring system” denotes a ring system wherein the two constituent rings have two adjacent atoms in common.
• nitrogen-containing heterocycles can form N-oxides since the nitrogen requires an available lone pair for oxidation to the oxide; one skilled in the art will recognize those nitrogen-containing heterocycles which can form N-oxides.
• nitrogen-containing heterocycles which can form N-oxides.
• tertiary amines can form N-oxides.
• salts also include those formed with organic or inorganic bases such as pyridine, triethylamine or ammonia, or amides, hydrides, hydroxides or carbonates of sodium, potassium, lithium, calcium, magnesium or barium. Accordingly, the present invention comprises compounds selected from Formula 1, N-oxides and suitable salts thereof.
• Embodiment 19c A compound of Formula 1 wherein R 1 is phenyl or pyridinyl, each unsubstituted or substituted with up to 4 substituents independently selected from R 4 .
• 5-thiazolyl 2 ⁇ fiuoro-5-thiazolyl, 2-methyl-5-thiazolyl, 2-(difluoromethyl)-5- thiazolyl, 2-(trifluoromethyl)-5-thiazolyl or 5-thiazolyl.
• Q is Q-1 Q-2 Q-3
• Embodiment Bl The compound of Embodiment B wherein R 1 is phenyl, unsubstituted or substituted with up to 4 substituents independently selected from R 4 .
• Embodiment El A compound of Embodiment E wherein R 1 is phenyl, unsubstituted or substituted with up to 4 substituents independently selected from R 4 .
• Liquid diluents also include alkylated fatty acids (e.g., methylated, ethylated, butylated) wherein the fatty acids may be obtained by hydrolysis of glycerol esters from plant and animal sources, and can be purified by distillation.
• alkylated fatty acids e.g., methylated, ethylated, butylated
• Typical liquid diluents are described in Marsden, Solvents Guide, 2nd Ed., Interscience, New York, 1950.
• Nonionic surfactants useful for the present compositions include, but are not limited to: alcohol alkoxylates such as alcohol alkoxylates based on natural and synthetic alcohols (which may be branched or linear) and prepared from the alcohols and ethylene oxide, propylene oxide, butylene oxide or mixtures thereof; amine ethoxylates, alkanolamides and ethoxylated alkanolamides; alkoxylated triglycerides such as ethoxylated soybean, castor and rapeseed oils; alkyiphenoi alkoxylates such as octylphenol ethoxylates, nonylphenol ethoxylates, dinonyl phenol ethoxylates and dodecyl phenol ethoxylates (prepared from the phenols and ethylene oxide, propylene oxide, butylene oxide or mixtures thereof); block polymers prepared from ethylene oxide or propylene oxide or propylene oxide or mixtures thereof); block polymers prepared
• Useful cationic surfactants include, but are not limited to: amides and ethoxylated amides; amines suc as N-alkyl propanediamines, tripropylenetriamines and dipropylenetetramines, and ethoxylated amines, ethoxylated diamines and propoxylated amines (prepared from the amines and ethylene oxide, propylene oxide, butylene oxide or mixtures thereof); amine salts such as amine acetates and diamine salts; quaternary ammonium salts such as quaternary salts, ethoxylated quaternary salts and diquatemary salts; and amine oxides such as alkyldimethylamine oxides and bis-(2-hydroxyethyl) ⁇ alkylamine oxides.
• Hymenoptera including bees (including carpenter bees), hornets, yellow jackets, wasps, and sawflies (Neodiprion spp.; Cephas spp.); insect pests of the order Isoptera including termites in the Tennitidae (e.g., Macrotermes sp., Odonlotermes obesus Rambur), Kalotermitidae (e.g., Cryptotermes sp.), and Rhinotermitidae (e.g., Reticulitermes sp., Coptotermes sp., Heterotermes tenuis Hagen) families, the eastern subterranean termite (Reticulitermes flavipes Kollar), western subterranean termite (Reticulitermes hesperus Banks), Formosan subterranean termite (Coptotermes formosanus Shiraki), West Indian drywood termite (Incisitermes immigran
• invertebrate pests of stored grain include larger grain borer (Prostephanus truncatus), lesser grain borer (Rhyzopertha dominica), rice weevil (Stiophilus oryzae), maize weevil (Stiophilus zeamais), cowpea weevil (Callosobruchus maculatus), red flour beetle (Tribolium castaneum), granary weevil (Stiophilus granarius), Indian meal moth (Plodia inte punctella), Mediterranean flour beetle (Ephestia kuhniella) and flat or rusty grain beetle (Cryptolestis ferrugineus).
• a method for controlling an invertebrate pest comprising contacting the invertebrate pest or its environment with a biologically effective amount of a compound of the present invention or with a composition comprising a biologically effective amount of a compound of the present invention.
• this method wherein the environment is soil and the composition is applied to the soil as a soil drench formulation.
• compounds of this invention are also effective by localized application to the locus of infestation.

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• Life Sciences & Earth Sciences (AREA)
• Organic Chemistry (AREA)
• Chemical & Material Sciences (AREA)
• Health & Medical Sciences (AREA)
• General Health & Medical Sciences (AREA)
• Dentistry (AREA)
• Engineering & Computer Science (AREA)
• Plant Pathology (AREA)
• Wood Science & Technology (AREA)
• Zoology (AREA)
• Environmental Sciences (AREA)
• Pest Control & Pesticides (AREA)
• Agronomy & Crop Science (AREA)
• Veterinary Medicine (AREA)
• Animal Behavior & Ethology (AREA)
• Public Health (AREA)
• General Chemical & Material Sciences (AREA)
• Medicinal Chemistry (AREA)
• Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
• Pharmacology & Pharmacy (AREA)
• Agricultural Chemicals And Associated Chemicals (AREA)
• Tropical Medicine & Parasitology (AREA)
• Chemical Kinetics & Catalysis (AREA)
• Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
• Plural Heterocyclic Compounds (AREA)
• Pretreatment Of Seeds And Plants (AREA)
• Nitrogen Condensed Heterocyclic Rings (AREA)
• Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)

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Citations (18)

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• 2018
  • 2018-05-04 WO PCT/US2018/031097 patent/WO2018208595A1/en not_active Ceased
  • 2018-05-04 EP EP18729821.1A patent/EP3621964B1/en active Active
  • 2018-05-04 US US16/612,097 patent/US11044910B2/en active Active
  • 2018-05-04 JP JP2019561815A patent/JP7244441B2/ja active Active
  • 2018-05-04 CN CN201880045654.2A patent/CN110869370B/zh active Active
  • 2018-05-04 BR BR112019023474-8A patent/BR112019023474B1/pt active IP Right Grant
  • 2018-05-04 MX MX2019013133A patent/MX2019013133A/es unknown
  • 2018-05-04 ES ES18729821T patent/ES2912385T3/es active Active
  • 2018-05-04 KR KR1020197036153A patent/KR102604099B1/ko active Active

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Non-Patent Citations (28)

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