WO2018184125A1 - Preparation method of dehydrating and crushing algae, preferably kelp-type algae (noage marine), which is mixed with a grape seed extract, for food-related, nutritional, dietary and therapeutic purposes - Google Patents

Preparation method of dehydrating and crushing algae, preferably kelp-type algae (noage marine), which is mixed with a grape seed extract, for food-related, nutritional, dietary and therapeutic purposes Download PDF

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Publication number
WO2018184125A1
WO2018184125A1 PCT/CL2018/000009 CL2018000009W WO2018184125A1 WO 2018184125 A1 WO2018184125 A1 WO 2018184125A1 CL 2018000009 W CL2018000009 W CL 2018000009W WO 2018184125 A1 WO2018184125 A1 WO 2018184125A1
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Prior art keywords
powder
grape
brown
algae
kelp
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PCT/CL2018/000009
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Spanish (es)
French (fr)
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Patricio FIGUEROA LIZAMA
Andrea Inés Isabel CERDA GONZALEZ
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Figueroa Lizama Patricio
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    • AHUMAN NECESSITIES
    • A23FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23LFOODS, FOODSTUFFS, OR NON-ALCOHOLIC BEVERAGES, NOT COVERED BY SUBCLASSES A21D OR A23B-A23J; THEIR PREPARATION OR TREATMENT, e.g. COOKING, MODIFICATION OF NUTRITIVE QUALITIES, PHYSICAL TREATMENT; PRESERVATION OF FOODS OR FOODSTUFFS, IN GENERAL
    • A23L29/00Foods or foodstuffs containing additives; Preparation or treatment thereof
    • A23L29/20Foods or foodstuffs containing additives; Preparation or treatment thereof containing gelling or thickening agents
    • A23L29/206Foods or foodstuffs containing additives; Preparation or treatment thereof containing gelling or thickening agents of vegetable origin
    • A23L29/256Foods or foodstuffs containing additives; Preparation or treatment thereof containing gelling or thickening agents of vegetable origin from seaweeds, e.g. alginates, agar or carrageenan
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/02Algae
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/14Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/14Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/16Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/48Preparations in capsules, e.g. of gelatin, of chocolate

Definitions

  • the invention is in the food, nutritional, dietary and therapeutic field and certain components and foods.
  • seaweeds are rich in a wide range of amino acids, trace elements and 30 vitamins, they also contain bioactive polysaccharides, carotenes, fucoidans, tocopherols and unsaturated fatty acids with antioxidant, immunomodulatory and antimicrobial activity
  • patent of invention ES 2252965 refers to the procedure for obtaining a highly purified alginate composition based on a polymeric mixture of manuronic acid and guluronic acid, in which the average molecular weight of the polymer mixture is greater than 350 kd, with the following steps: a) extracting the material based on algae in a solution with a complexing agent, b) sediment the cellular components and particles with a porous binder c) filter the solution d) precipitate the alginate from the solution and e) collect and dehydrate the precipitated alginate, after which they are repeated steps a) to e) at least once, and f) dissolve the alginate and obtain at least one other alginate precipitate.
  • the invention consists of a process for the preparation of dehydration and pulverization of seaweed, preferably of the brown type (Noage marine), endowed with perfected biological effects, which is mixed with a grape seed extract, for nutritional, nutritional, dietary and therapeutic purposes.
  • Brown or pheophyllic algae (Phaeophyceae), is a gas group included in the kingdom kingdom. They are not true plants because they are classified in the Heteromonyphyta group. It comprises about 265 genera with about 1500-2000 species, mainly marine because only six genera are freshwater. Brown algae are the main primary producers of several communities of animals and protists.
  • Macrocystis which forms prominent underwater forests, can reach up to 60 m in length. They also occur in free floating forms, such as Sargassum, which forms large areas (the size of a province) in the Sargasso Sea.
  • Brown algae comprise differentiated contained multicellular forms. They usually have rhizoid, stipe and sheets.
  • the stipe in some ways may be provided with a sieve of tubes capable of transporting water and products of photosynthesis.
  • pigments have chlorophylls a, Ci and c 2 and fucoxanthin. The latter is responsible for the brown color that these algae present.
  • Chloroplasts are surrounded by four membranes, so they are supposed to be the result of secondary endosymbiosis of a red algae.
  • the invention to be patented refers to a process for obtaining a powdered brown seaweed product (Noage marine) and then producing a mixture or connective composition of Chilean grape pepa, as for use in the control of overweight, obesity, Insulin disorders, diabetes, control of acanthosis nigricans, use in the prevention of Cellulite and lymphatic circulation problems, venous problems and fluid retention, for the treatment of premenstrual syndrome and as sunscreen / blocker.
  • the process or procedure to obtain a powdered brown seaweed product and an extract of black grape pepa comprises the following steps:
  • Brown algae is extracted and soaked for 4 to 6 hours, preferably between 1 and 10 hours, in fresh water, in order to eliminate sodium.
  • the proportion of the product mixture between the marine parga powder and the grape seed extract comprises 5% to 97% brown seaweed powder and 10% grape seed extract, more preferably 85% of brown seaweed powder and 15% and even more preferred of 75% brown seaweed powder and 25% of extract or powder of grape pepa.
  • the product is used in capsules, syrups, solutions, juices, injectables and creams, ointments, spray, aerosol, nanosomes, liposomes and lyophilized products.
  • the composition or mixture of brown seaweed with grape seed extract usable to combat overweight, obesity and others for people, comprises: 5% to 97% brown seaweed dust and 5% to 1 0% grape seed extract, more preferably 85% brown seaweed powder and 1 5% and even more preferably 75% brown seaweed powder and a 25% grape pepa extract.
  • Another example includes: 1% to 75% brown seaweed powder and 10% to 35% grape seed extract.
  • Another example includes: 1.0% to 85% brown seaweed powder and 20% to 45% grape seed extract.
  • Another example includes; 25% to 65% brown seaweed powder and 1 to 5% to 35% grape seed extract.

Abstract

The invention relates to a preparation method of dehydrating and crushing algae, preferably kelp-type algae (Noage marine), provided with improved biological effects, and which is mixed with a grape seed extract, for food-related, nutritional, dietary and therapeutic purposes, characterised by comprising the following steps: a) extracting the kelp and soaking same for 4 to 6 hours, preferably between 1 and 10 hours, in fresh water in order to remove the sodium; 2) then introducing the kelp into an oven and dehydrating same at a temperature between 10°C and 30°C, preferably between 5°C and 50°C; 3) once the kelp is dehydrated, introducing same into a crushing mill, which converts the kelp into a fine powder; 4) combining or mixing the kelp powder obtained from the mill with a Chilean grape seed extract, which is extracted in the following manner: a) the grape is pressed and the seed and the skin is obtained and then dehydrated in ovens at a temperature between 10°C and 30°C, preferably between 5°C and 50°C; b) once the grape seed is dehydrated it is crushed with a mill; and c) finally the marine kelp powder and the grape seed powder are mixed, and encapsulated.

Description

"PROCEDIMIENTO PARA LA PREPARACIÓN DE DES HIDRAT ACIÓN Y PULVERIZACIÓN DE ALGAS PREFERENTEMENTE DEL TIPO PARDAS NOAGE MARINE, QUE SE MEZCLA CON UN EXTRACTO DE PEPA DE UVA, CON FI NES NUTRITIVOS, ALIMENTICIOS, DIETÉTICOS Y TERAPÉUTICOS"  "PROCEDURE FOR THE PREPARATION OF DES HIDRAT ATION AND SPRAYING OF SOMETHING PREFERREDLY OF THE NODE MARINE WALLS TYPE, WHICH MIXES WITH A GRAPE PEPA EXTRACT, WITH NUTRITIVE, FOOD, DIETETIC AND THERAPEUTIC FESTS"
ANTECEDENTES DE A INVENCION BACKGROUND OF THE INVENTION
Campo de la invención Field of the Invention
La invención se encuentra en el campo alimenticio, nutritivo, dietético y terapéutico y ciertos componentes y alimentos. The invention is in the food, nutritional, dietary and therapeutic field and certain components and foods.
Descripción del Arte Previo Description of the Prior Art
Desde tiempos inmemoriales la humanidad ha empleado las algas con fines nutritivos y alimenticios. Así, las algas son. consumidas principalmente por los pueblos del Extremo Oriente; sin embargo, recientemente también se vienen utilizando en forma seca en países desarrollados. Constituyen unos vehículos de materiales nutritivos altamente valiosos, puesto que su forma seca contiene elevadas concentraciones de sustancias que son esenciales para una vida sana, tales como vitaminas, proteínas, complejos de micro elementos proteínicos, sacáridos, ácidos grasos poliinsaturados y similares. En los años . recientes, la contaminación ambiental ha llegado a representar un problema de alcance mundial. Actualmente, la contaminación de los mares y océanos por metales pesados tóxicos (por ejemplo, plomo, mercurio, cadmio, cobre, etc. ), así como por agentes inductores de formaciones tumorales (por ejemplo, compuestos aromáticos policíclicos condensados), no carece de importancia. Representa un difícil problema el hecho de que tales agentes se acumulen en el organismo de las algas. Así, las "algas completas" obtenidas del mar o cultivadas bajo otras condiciones naturales no pueden usarse a efectos de nutrición humana o animal, alimentación cosmética y terapia; solamente pueden emplearse las fracciones de las "algas completas" que hayan sido previamente purificadas de materiales biológicamente nocivos. Carames de Guovéa, por ejemplo, describe un procedimiento de purificación de este tipo [Cosmetics and Toiletries 95. 47 (1 980)]. Sin embargo, una operación de purificación supone una intervención que descompone parte de las sustancias biológicamente activas del alga, con lo que el valor biológico de la fracción de alga así obtenida queda notablemente disminuido [Zajic: Properties and Products of Algae: Edición Planum, Nueva York, ( 1970)]. Since time immemorial humanity has used algae for nutritional and nutritional purposes. So, the algae are. consumed mainly by the peoples of the Far East; However, recently they have also been used in dry form in developed countries. They constitute highly valuable nutritional material vehicles, since their dry form contains high concentrations of substances that are essential for a healthy life, such as vitamins, proteins, complexes of micro protein elements, saccharides, polyunsaturated fatty acids and the like. In the years . In recent years, environmental pollution has come to represent a global problem. Currently, pollution of the seas and oceans by toxic heavy metals (e.g. lead, mercury, cadmium, copper, etc. ), as well as by agents that induce tumor formations (for example, condensed polycyclic aromatic compounds), is not unimportant. The fact that such agents accumulate in the algae organism represents a difficult problem. Thus, "complete algae" obtained from the sea or cultivated under other natural conditions cannot be used for human or animal nutrition, cosmetic feeding and therapy purposes; Only "whole algae" fractions that have been previously purified from biologically harmful materials can be used. Carames de Guovéa, for example, describes such a purification procedure [Cosmetics and Toiletries 95. 47 (1 980)]. However, a purification operation involves an intervention that breaks down part of the algae's biologically active substances, so that the biological value of the algae fraction thus obtained is markedly diminished [Zajic: Properties and Products of Algae: Planum Edition, New York, (1970)].
Se sabe que las algas marinas son ricas en una amplia gama de aminoácidos, oligoelementos y 30 vitaminas, también contienen polisacáridos bioactivos, carotenos, fucoidanos, tocoferoles y ácidos grasos insaturados con propiedades antioxidantes, inmunomoduladoras y actividad antimicrobiana It is known that seaweeds are rich in a wide range of amino acids, trace elements and 30 vitamins, they also contain bioactive polysaccharides, carotenes, fucoidans, tocopherols and unsaturated fatty acids with antioxidant, immunomodulatory and antimicrobial activity
En lo que se refiere al estado de la técnica para el uso de algas marinas, de uso como un producto para evitar la obesidad dietético o lo similar, podemos citar patentede invención ES 2252965, la que se refiere a procedimiento para la obtención de una composición de alginato altamente purificado a base de una mezcla polimérica de ácido manurónico y ácido gulurónico, en el cual el peso molecular medio de la mezcla polimérica es mayor de 350 kd, con las etapas siguientes: a) extraer el material a base de algas en una solución con un formador de complejos, b) sedimentar los componentes celulares y las partículas con un aglutinante poroso c) filtrar la solución d) precipitar el alginato de la solución y e) recoger y deshidratar el alginato precipitado, después de lo cual se repiten las etapas a) hasta e) al menos una vez, y f) disolver el alginato y obtener al menos otro precipitado del alginato. Regarding the state of the art for the use of seaweed, for use as a product to avoid dietary obesity or the like, we can cite patent of invention ES 2252965, which refers to the procedure for obtaining a highly purified alginate composition based on a polymeric mixture of manuronic acid and guluronic acid, in which the average molecular weight of the polymer mixture is greater than 350 kd, with the following steps: a) extracting the material based on algae in a solution with a complexing agent, b) sediment the cellular components and particles with a porous binder c) filter the solution d) precipitate the alginate from the solution and e) collect and dehydrate the precipitated alginate, after which they are repeated steps a) to e) at least once, and f) dissolve the alginate and obtain at least one other alginate precipitate.
DESCRIPCIÓN DETALLADA DE LA INVENCIÓN DETAILED DESCRIPTION OF THE INVENTION
Resumen de la Invención. Summary of the Invention
La invención consiste en un procedimiento para la preparación de deshidratación y pulverización de algas preferentemente del tipo pardas (Noage marine), dotadas de perfeccionados efectos biológicos, que se mezcla con un extracto de pepa de uva, con fines nutritivos, alimenticios, dietéticosy terapéuticos. The invention consists of a process for the preparation of dehydration and pulverization of seaweed, preferably of the brown type (Noage marine), endowed with perfected biological effects, which is mixed with a grape seed extract, for nutritional, nutritional, dietary and therapeutic purposes.
Descripción detallada de la Invención Detailed description of the invention
Las algas pardas o feofíceas (Phaeophyceae), es un grupo dealgasincluido en el reinoProtista. No son verdaderasplantaspues se clasifican en el grupoHeterokontophyta. Comprende unos 265 géneros con unas 1500-2000 especies, principalmente marinos pues sólo seis géneros son de agua dulce. Las algas pardas son los principales productores primarios de varias comunidades de animales y protistas. Brown or pheophyllic algae (Phaeophyceae), is a gas group included in the kingdom kingdom. They are not true plants because they are classified in the Heterokontophyta group. It comprises about 265 genera with about 1500-2000 species, mainly marine because only six genera are freshwater. Brown algae are the main primary producers of several communities of animals and protists.
La mayoría viven en las costas rocosas de las zonas templadas y subpolares, dominando la zona intermareal como en el caso de las Fucales y Laminariales. Macrocystis, que forma bosques submarinos prominentes, puede alcanzar hasta 60 m de longitud. También se presentan en formas flotantes libres, como Sargassum, que forma grandes extensiones (del tamaño de una provincia) en elMar de los Sargazos. The majority live on the rocky coasts of the temperate and subpolar zones, dominating the intertidal zone as in the case of the Fucales and Laminariales. Macrocystis, which forms prominent underwater forests, can reach up to 60 m in length. They also occur in free floating forms, such as Sargassum, which forms large areas (the size of a province) in the Sargasso Sea.
Las algas pardas comprenden formas pluricelulares contejidos diferenciados. Generalmente presentan rizoide, estipe y láminas. El estipe de algunas formas puede estar provisto de un tamiz de tubos capaces de transportar agua y productos de la fotosíntesis. Como pigmentos presentan clorofilas a, Ci y c2 y fucoxantina. Este último es el responsable del color pardo que presentan estas algas. Los cloroplastos están rodeados de cuatro membranas, por lo que se supone que son el resultado de laendosimbiosis secundaria de un alga roja. Brown algae comprise differentiated contained multicellular forms. They usually have rhizoid, stipe and sheets. The stipe in some ways may be provided with a sieve of tubes capable of transporting water and products of photosynthesis. As pigments have chlorophylls a, Ci and c 2 and fucoxanthin. The latter is responsible for the brown color that these algae present. Chloroplasts are surrounded by four membranes, so they are supposed to be the result of secondary endosymbiosis of a red algae.
La invención que se desea patentar se refiere a un proceso para obtener un producto pulverizado de algas pardas (Noage marine) y luego producir una mezcla o composición conextracto de pepa de uva chilena, como para el uso en el control del sobrepeso, la obesidad , trastornos de la insulina, la diabetes, control de la acantosis nigricans, uso en la prevención de la celulitis y los problemas de la circulación linfática, problemas venosos y de retención de líquidos, para el tratamiento del síndrome premenstrual y como bloqueador/protector solar. The invention to be patented refers to a process for obtaining a powdered brown seaweed product (Noage marine) and then producing a mixture or connective composition of Chilean grape pepa, as for use in the control of overweight, obesity, Insulin disorders, diabetes, control of acanthosis nigricans, use in the prevention of Cellulite and lymphatic circulation problems, venous problems and fluid retention, for the treatment of premenstrual syndrome and as sunscreen / blocker.
Podemos citar como ejemplos de la mezcla entre el alga marina parda y el extracto de uva como aplicación o uso: We can cite as examples of the mixture between brown seaweed and grape extract as application or use:
a) para el control del sobrepeso y la obesidad  a) for the control of overweight and obesity
b) para los trastornos de la insulina y la diabetes  b) for insulin disorders and diabetes
c) Para un potente control de la acantosis nigricans  c) For a powerful control of acanthosis nigricans
d) para el tratamiento y la prevención de la celulitis y los problemas de la circulación linfática  d) for the treatment and prevention of cellulite and lymphatic circulation problems
e) para los problemas venosos y de retención de liquido f) para la prevención y tratamiento del síndrome premenstrual. g) como bloqueador/protector solarcomo antialérgico y en la dermatitis atópica.  e) for venous and fluid retention problems f) for the prevention and treatment of premenstrual syndrome. g) as sunscreen / sunscreen as antiallergic and in atopic dermatitis.
El proceso o procedimiento para obtener un producto pulverizado de algas marinas pardas y un extracto de pepa de uva negra, comprende las siguientes etapas: The process or procedure to obtain a powdered brown seaweed product and an extract of black grape pepa comprises the following steps:
1 ) Se extrae las algas pardas y se pone en remojo por 4 a 6horas de preferencia entre 1 a 1 0 horas, en agua dulce, de manera de eliminar el sodio. 1) Brown algae is extracted and soaked for 4 to 6 hours, preferably between 1 and 10 hours, in fresh water, in order to eliminate sodium.
2) Luego se introducen en un horno y se deshidratan a una temperatura de entre 10°C a 30°C, de preferencia de 5°C a 50°C 2) Then they are placed in an oven and dehydrated at a temperature between 10 ° C to 30 ° C, preferably from 5 ° C to 50 ° C
3) Una vez deshidratada el alga parda, seintroduce en un molino pulverizador, que convierte el alga parda en un polvillo fino. 4) El polvillo obtenido del molino de alga parda, se combina o mezcla con un extracto de pepa de uva la cual se extrae de la siguiente manera: 3) Once the brown seaweed is dehydrated, it is introduced into a spray mill, which converts the brown seaweed into a fine powder. 4) The powder obtained from the brown seaweed mill is combined or mixed with an extract of grape pepa which is extracted as follows:
a) La uva se prensa, y se obtiene la pepa y la piely luego se deshidrataen hornos a una temperatura entre 10°C a 30°C, de preferencia entre 5°C a 50°C.  a) The grapes are pressed, and the pepa and the pie are obtained and then ovens are dehydrated at a temperature between 10 ° C to 30 ° C, preferably between 5 ° C to 50 ° C.
b) Una vez deshidratada la pepa de uva.se pulveriza con un molino.  b) Once the grape pepa is dehydrated, it is pulverized with a mill.
c) La mezcla entre el polvillo del alga marina parda y de la pepa de uva se encapsulan.  c) The mixture between the brown seaweed and grape seed powder is encapsulated.
La proporción de la mezcla del producto entre el polvillo dealga marina parday el extracto o polvillo de pepa de uva comprende, un 5%a 97% de polvillo de algas pardas y un 10% de extracto de pepa de uva, más preferentemente un 85% de polvillo de alga parda y un 15% y aún más preferente de un 75% de polvillo de algas pardas y un 25% de extracto o polvillo de pepa de uva. The proportion of the product mixture between the marine parga powder and the grape seed extract comprises 5% to 97% brown seaweed powder and 10% grape seed extract, more preferably 85% of brown seaweed powder and 15% and even more preferred of 75% brown seaweed powder and 25% of extract or powder of grape pepa.
El producto se utiliza en cápsulas, jarabes, soluciones, jugos, inyectables y en cremas, ungüentos, spray, aerosol, nanósomas, liposomas y productos liofilizados. The product is used in capsules, syrups, solutions, juices, injectables and creams, ointments, spray, aerosol, nanosomes, liposomes and lyophilized products.
Como ejemplos de realización As examples of realization
La composición o mezcla de algas marinas pardas con el extracto de pepa de uva, utilizable para combatir el sobrepeso, obesidad y otros para personas, comprende: un 5% a 97% depolvillo de algas marinas pardas y un 5% a 1 0% de extracto de pepa de uva, más preferentemente un 85% de polvillo de alga parda y un 1 5% y aún más preferente de un 75% de polvillo de algas pardas y un 25% de extracto de pepa de uva. The composition or mixture of brown seaweed with grape seed extract, usable to combat overweight, obesity and others for people, comprises: 5% to 97% brown seaweed dust and 5% to 1 0% grape seed extract, more preferably 85% brown seaweed powder and 1 5% and even more preferably 75% brown seaweed powder and a 25% grape pepa extract.
Otro ejemplo, comprende: un 1 % al 75% de polvillo de algas marinas pardas y un 10% a 35% de extracto de pepa de uva. Another example includes: 1% to 75% brown seaweed powder and 10% to 35% grape seed extract.
Otro ejemplo, comprende: un 1 0% al 85% de polvillo de algas marinas pardas y un 20% a 45% de extracto de pepa de uva. Another example includes: 1.0% to 85% brown seaweed powder and 20% to 45% grape seed extract.
Otro ejemplo, comprende; un 25% a 65% de polvillo de algas marinas pardas y un 1 5% a un 35% de extracto de pepa de uva. Another example includes; 25% to 65% brown seaweed powder and 1 to 5% to 35% grape seed extract.

Claims

REIVINDICACIONES Procedimiento para la preparación de deshidratación y pulverización de algas preferentemente del tipo de algas pardas (Noage marine) , dotadas de perfeccionados efectos biológicos, que se mezcla con un extracto de pepa de uva, con fines nutritivos, alimenticios, dietéticos y terapéuticos CARACTERIZADO porque comprende las siguientes etapas: a) se extrae las algas pardas y se pone en remojo por 4 a 6 horas de preferencia entre 1 a 10 horas, en agua dulce, de manera de eliminar el sodio; CLAIMS Procedure for the preparation of dehydration and pulverization of seaweed, preferably of the type of brown algae (Noage marine), equipped with improved biological effects, which is mixed with a grape seed extract, for nutritional, nutritional, dietary and therapeutic purposes CHARACTERIZED because It comprises the following steps: a) brown algae is extracted and soaked for 4 to 6 hours, preferably between 1 to 10 hours, in fresh water, so as to eliminate sodium;
b) luego se introducen en un horno y se deshidratan a una temperatura de entre 1 0°C a 30°C, de preferencia de 5°C a 50°C; b) they are then placed in an oven and dehydrated at a temperature between 10 ° C to 30 ° C, preferably 5 ° C to 50 ° C;
c) una vez deshidratada el alga parda, se introduce en un molino pulverizador, que convierte el alga parda en un polvillo fino; c) once the brown seaweed is dehydrated, it is introduced into a spray mill, which converts the brown seaweed into a fine powder;
d) el polvillo obtenido del molino de alga parda, se combina o mezcla con un extracto de pepa de uva chilena, la cual se extrae de la siguiente manera: a) la uva se prensa, y se obtiene la pepa y la piel y luego se deshidrata en hornos a una temperatura entre 1 0°C a 30°C, de preferencia entre 5°C a 50°C; d) the powder obtained from the brown seaweed mill, is combined or mixed with an extract of Chilean grape pepa, which is extracted as follows: a) the grape is pressed, and the pepa and the skin are obtained and then it is dehydrated in ovens at a temperature between 10 ° C to 30 ° C, preferably between 5 ° C to 50 ° C;
e) una vez deshidratada la pepa de uva, se pulveriza con un molino; y. e) once the grape pepa is dehydrated, it is pulverized with a mill; Y.
f) finalmente se mezcla el polvillo del alga marina parda y el polvo de la pepa de uva, se encapsulan. f) finally the brown seaweed powder and the grape peel powder are mixed, encapsulated.
2. Mezcla de la preparación de deshidratación y pulverización de algas preferentemente del tipo pardas y de la pepa de uva, según la reivindicación 1 , CARACTERIZADA porque La proporción de la mezcla entre el polvillo de alga marina parda y el extracto o polvillo de pepa de uva, comprende: un 5%a 97% de polvillo de algas pardas y un 1 0% de extracto o polvillo de pepa de uva, más preferentemente un 85% de polvillo de alga parda y un 15% y aún más preferente de un 75% de polvillo de algas pardas y un 25% de extracto o polvillo de pepa de uva. 2. Mixture of the preparation of dehydration and pulverization of seaweed, preferably of the brown type and of the grape peel, according to claim 1, CHARACTERIZED in that the proportion of the mixture between the brown seaweed powder and the extract or pepa extract powder grape, comprises: 5% to 97% brown algae powder and 1 0% grape extract or powder, more preferably 85% brown seaweed powder and 15% and even more preferably 75 % of brown seaweed powder and 25% of extract or powder of grape pepa.
3. Uso del producto de la mezcla entre la pulverización entre el alga marina parda y la pulverización de pepa de uva, según las reivindicaciones 1 y 2, CARACTERIZADO porque dicha mezcla se puede presentar en cápsulas, como jarabes, soluciones, jugos, inyectables y en cremas, ungüentos, spray, aerosol, nanósomas, liposomas y productos liofilizados. 3. Use of the product of the mixture between the spray between the brown seaweed and the spray of grape seed, according to claims 1 and 2, CHARACTERIZED because said mixture can be presented in capsules, such as syrups, solutions, juices, injectables and in creams, ointments, spray, spray, nanosomes, liposomes and lyophilized products.
PCT/CL2018/000009 2017-04-04 2018-03-28 Preparation method of dehydrating and crushing algae, preferably kelp-type algae (noage marine), which is mixed with a grape seed extract, for food-related, nutritional, dietary and therapeutic purposes WO2018184125A1 (en)

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CL2017000805A CL2017000805A1 (en) 2017-04-04 2017-04-04 Process for the preparation of dehydration and pulverization of seaweed, preferably of the brown noage marine type, which is mixed with a grape seed extract, for nutritional, nutritional, dietary and therapeutic purposes.

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CN105341946A (en) * 2015-12-14 2016-02-24 北京康比特体育科技股份有限公司 Dunaliella salina, lutein and huckleberry composition, soft capsule containing composition and preparation method of soft capsule
RU2589705C2 (en) * 2014-09-10 2016-07-10 Дина Давидовна Абакумова Biologically active preparation based on algae
US9439939B2 (en) * 2014-04-01 2016-09-13 Webseed, Inc. Heavy metals defense
CN106692955A (en) * 2016-12-30 2017-05-24 浙江海洋大学 Seaweed extract healthcare product having anti-aging effect and preparation method of seaweed extract healthcare product

Patent Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US9439939B2 (en) * 2014-04-01 2016-09-13 Webseed, Inc. Heavy metals defense
RU2589705C2 (en) * 2014-09-10 2016-07-10 Дина Давидовна Абакумова Biologically active preparation based on algae
CN105341946A (en) * 2015-12-14 2016-02-24 北京康比特体育科技股份有限公司 Dunaliella salina, lutein and huckleberry composition, soft capsule containing composition and preparation method of soft capsule
CN106692955A (en) * 2016-12-30 2017-05-24 浙江海洋大学 Seaweed extract healthcare product having anti-aging effect and preparation method of seaweed extract healthcare product

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