RU2589705C2 - Biologically active preparation based on algae - Google Patents

Abstract

FIELD: pharmaceutics.

SUBSTANCE: invention relates to chemical-pharmaceutical industry, specifically to a preparation based on algae. Biologically active preparation based on algae containing algae Spirulina Platensis and seaweed Laminaria japonica in form of hydrolysate, CO₂ extract of herbs, selected from: algae extract Fucus vesiculosus, horse chestnut extract, ivy extract, ginger extract, grape seed extract, guarana extract, green tea extract, and also contains glycerine, lanolin, vegetable oil or mixture of vegetable oils, xanthan in certain proportions.

EFFECT: above preparation based on algae has a higher therapeutic effect.

2 cl, 9 ex

Description

The invention relates to the pharmaceutical industry, in particular to the creation of agents with a wide range of pharmacological effects used in cosmetology, thalassotherapy, balneotherapy and physiotherapy, including procedures using hardware-based methods of exposure (e.g., electrophoresis, laser phoresis, magnetophoresis, ultraphonophoresis and other).

A biologically active preparation based on marine plant materials is known (RF Patent 2283124, IPC A61K 36/02, publ. 2006), which contains spirulina enriched with selenium, brown seaweed from the group comprising kelp, zooster and fucus.

The disadvantage of this drug is its predominant use as an oral agent.

The closest is a balneological treatment and prophylactic agent (RF Patent 2218149, IPC A61K 8/97, publ. 2003) based on carnallite, including a biologically active additive - extracts of medicinal plants and / or seaweed powder, water-glycerin hydrochloride complex, polysaccharides and sodium chloride.

The disadvantage of this therapeutic agent is the lack of indications for its use in physiotherapy procedures using hardware methods of exposure.

The objective of the invention is to obtain a biologically active drug that has extended indications for use with targeted differentiated effects on certain types of nosology, namely in cosmetology, thalassotherapy, balneotherapy and physiotherapy, with a wider range of applications in balneological and physiotherapeutic procedures, including hardware exposure methods (e.g., electrophoresis, laser phoresis, magnetophoresis, ultraphonophoresis, etc.).

The stated objective is achieved in that in a biologically active preparation based on algae containing CO2 extracts of medicinal plants, algae, glycerin, it is new that the preparation contains Spirulina Platensis algae and Laminaria japonica algae in the form of a hydrolyzate. The extract used is a CO2 extract of medicinal plants selected from the group: Fucus vesiculosus algae extract, horse chestnut extract, ivy extract, ginger extract, grape seed extract, guarana extract, green tea extract, as well as the preparation contains lanolin, vegetable oil or a mixture of vegetable oils, xanthan gum in the following ratio of components, wt. %:

algae hydrolyzate Laminaria japonica 75-98% Algae Spirulina Platensis 0.01-5% CO2 extract of medicinal plants selected from the group: Fucus vesiculosus algae extract, horse chestnut extract, ivy extract, ginger extract, grape seed extract, guarana extract, green tea extract 0.01-10% glycerol 0.01-10% lanolin 0.01-10% vegetable oil or a mixture of vegetable oils 0.01-10% xanthan 0.01-2%

In addition, the biologically active preparation as a mixture of vegetable oils contains 0.005-0.5% of essential oil and 0.005-9.5 stone oil.

Introduction to the biologically active preparation of a complex of glycerol, lanolin and xanthan provides the ability to create drugs of different densities, high sliding ability of the composition with hardware and other types of exposure and transdermal activity of the drug. The resulting gels and masks are easily and evenly applied to the skin. This composition allows you to create a stable emulsion, providing the possibility of using plant extracts in aqueous and oil forms.

A feature of the proposed biologically active drug, which includes the hydrolyzate of algae Laminaria japonica, is that the cell walls are destroyed in it and this allows to increase the degree of penetration of both active substances of the algae into the skin tissue and is a conductor for medicinal extracts plants of the above group.

The proposed drug activates metabolic processes and blood supply to tissues, restores mineral balance, helps to eliminate toxins and excess fluids, remove swelling, moisturizes, tones and tightens the skin, improves skin color, smoothes wrinkles, and acts more effectively, as clinical observations have shown, on scar tissue with carrying out physiotherapeutic influences due to the fibrous (defibrosing) connective tissue action. In addition, the drug has anti-inflammatory and wound healing effects.

The introduction of a complex of glycerol, lanolin, and xanthan into a biologically active preparation provides the possibility of obtaining preparations of various densities, evaporation rates (drying times), and sliding ability, which makes it possible to increase the therapeutic effect of the natural components of the preparation when applying hardware methods of exposure.

The proposed 100% natural preparation can be used as applications, massage gels, bath gels and gels, suitable for use with various hardware methods of exposure with a higher therapeutic effect.

The ratio of wt. % of the elements in the composition during its manufacture is selected depending on the requirements in its application.

Example 1

A biologically active preparation based on algae - massage gel for the body contains 79.19 g (79.19 wt.%) Of an aqueous gel from brown alga Laminaria japonica, 0.01 g (0.01 wt.%) Algae Spirulina Platensis, 0, 2 g (0.2 wt.%) Of Fucus vesiculosus CO2 extract, 0.1 g (0.1 wt.%) Of horse chestnut CO2 extract, 0.1 g (0.01 wt.%) Of ginger CO2 extract, 10 g (10 wt.%) Glycerol, 5 g (5 wt.%) Lanolin, 0.3 g (0.3 wt.%) Xanthan gum, 2 g (2.0 wt.%) Grape seed oil, 3 g (3 , 0 wt.%) Almond oil, 0.05 g (0.05 wt.%) Clary sage essential oil, 0.05 g (0.05 wt.%) Sweet orange essential oil.

The starting components are loaded into the mixer and thoroughly mixed using a mechanical stirrer until a homogeneous consistency is obtained.

Example 2

A biologically active preparation based on algae - a face gel contains 91.0 g (91.0 wt.%) Of an aqueous gel from the brown alga Laminaria japonica, 0.2 g (0.2 wt.%) Of the alga Spirulina Platensis, 0.2 g (0.2 wt.%) of CO2 extract of Fucus vesiculosus, 0.1 g (0.1 wt.%) of CO2 extract of horse chestnut, 0.1 g (0.1 wt.%) of CO2 extract of grape seed, 5, 0 g (5.0 wt.%) Glycerol, 1.0 g (1.0 wt.%) Lanolin, 0.3 g (0.3 wt.%) Xanthan gum, 1.0 g (1.0 wt. %) grape seed oil, 1.0 g (1.0 wt.%) pine nut oil, 0.05 g (0.05 wt.%) clary sage essential oil, 0.05 g (0.05 wt.%) ) Limette essential oil.

The starting components are loaded into the mixer and thoroughly mixed using a mechanical stirrer until a homogeneous consistency is obtained.

Example 3

A biologically active preparation based on algae - a warming body mask contains 91.4 g (91.4 wt.%) Of an aqueous gel from brown alga Laminaria japonica, 2 g (2 wt.%) Algae Spirulina Platensis, 0.2 g (0 , 2 wt.%) Fucus vesiculosus CO2 extract, 0.1 g (0.1 wt.%) Horse chestnut CO2 extract, 0.1 g (0.2 wt.%) Ginger CO2 extract, 0.1 g (0 , 2 wt.%) Guarana CO2 extract, 2 g (2 wt.%) Glycerol, 1.0 g (1.0 wt.%) Lanolin, 1.5 g (1.5 wt.%) Xanthan gum, 1, 0 g (1.0 wt.%) Grape seed oil, 0.5 g (0.5 wt.%) Hot pepper oil, 0.1 g (0.1 wt.%) Cypress essential oil.

The starting components are loaded into the mixer and thoroughly mixed using a mechanical stirrer until a homogeneous consistency is obtained.

Example 4

A biologically active preparation based on algae - a face mask contains 91.3 g (91.3 wt.%) Of an aqueous gel from brown alga Laminaria japonica, 5.0 g (5.0 wt.%) Algae Spirulina Platensis, 0.1 g (0.2 wt.%) of CO2 extract of Fucus vesiculosus, 0.1 g (0.2 wt.%) of CO2 extract of green tea, 0.05 g (0.05 wt.%) of horse chestnut CO2 extract, 0, 05 g (0.05 wt.%) Grape seed CO2 extract, 1.0 g (1.0 wt.%) Glycerol, 0.5 g (0.5 wt.%) Lanolin, 0.8 g (0, 8 wt.%) Xanthan, 2 g (2.0 wt.%) Pine nut oil, 0.05 g (0.05 wt.%) Clary sage essential oil, 0.05 g (0.05 wt.%) essential oil limet.

The starting components are loaded into the mixer and thoroughly mixed using a mechanical stirrer until a homogeneous consistency is obtained.

Example 5

A biologically active preparation based on algae - a hair mask contains 90.3 g (90.3 wt.%) Of an aqueous gel from the brown alga Laminaria japonica, 0.2 g (0.2 wt.%) Of the alga Spirulina Platensis, 0.4 g (0.4 wt.%) CO2 extract of Fucus vesiculosus, 0.05 g (0.05 wt.%) CO2 extract of grape seed, 0.05 g (0.05 wt.%) CO2 extract of ginger, 0.5 g (0.5 wt.%) glycerol, 0.5 g (0.5 wt.%) lanolin, 0.7 g (0.7 wt.%) xanthan gum, 2.5 g (3.0 wt.% ) grape seed oil, 4.0 g (4.0 wt.%) pine nut oil, 0.2 g (0.2 wt.%) clary sage essential oil, 0.1 g (0.1 wt.%) essential oil limet.

The starting components are loaded into the mixer and thoroughly mixed using a mechanical stirrer until a homogeneous consistency is obtained.

Example 6

A biologically active preparation based on algae - a tonic foot mask contains 92.8 g (92.8 wt.%) Of an aqueous gel from brown alga Laminaria japonica, 2.0 g (2.0 wt.%) Algae Spirulina Platensis, 0, 3 g (0.3 wt.%) Of Fucus vesiculosus CO2 extract, 0.1 g (0.1 wt.%) Of horse chestnut CO2 extract, 0.1 g (0.1 wt.%) Of ivy CO2 extract, 1, 0 g (1.0 wt.%) Glycerol, 1.0 g (1.0 wt.%) Lanolin, 1.5 g (1.5 wt.%) Xanthan gum, 0.5 g (0.5 wt. %) grape seed oil, 0.5 g (0.5 wt.%) almond oil, 0.05 g (0.05 wt.%) clary sage essential oil, 0.075 g (0.075 wt.%) limetta essential oil 0.075 g (0.075 wt.%) Ether of oil of sweet orange.

The starting components are loaded into the mixer and thoroughly mixed using a mechanical stirrer until a homogeneous consistency is obtained.

Example 7

A biologically active preparation based on algae - a bath gel contains 91.76 g (91.76 wt.%) Of an aqueous gel from a brown alga Laminaria japonica, 0.2 g (0.2 wt.%) Of an alga Spirulina Platensis, 2.5 g (2.5 wt.%) Fucus vesiculosus CO2 extract, 2.5 g (2.5 wt.%) horse chestnut extract, 2.5 g (2.5 wt.%) grape seed extract, 0.01 g (0 , 01 wt.%) Glycerol, 0.01 g (0.01 wt.%) Lanolin, 0.01 g (0.01 wt.%) Xanthan, 0.01 g (0.01 wt.%) Grape oil seeds, 0.25 g (0.25 wt.%) clary sage essential oil, 0.25 g (0.25 wt.%) sweet orange essential oil.

The starting components are loaded into the mixer and thoroughly mixed using a mechanical stirrer until a homogeneous consistency is obtained.

Example 8

An algae-based biologically active preparation, an electrophoresis gel, contains 93.67 g (93.67 wt.%) Of an aqueous gel from brown alga Laminaria japonica, 0.01 g (0.01 wt.%) Of Spirulina Platensis alga, 0.01 g (0.01 wt.%) of the CO2 extract of Fucus vesiculosus, 6.0 g (6.0 wt.%) of glycerol, 0.01 g (0.01 wt.%) of lanolin, 0.3 g (0.3 wt.%) xanthan, 0.01 g (0.01 wt.%) grape seed oil.

The starting components are loaded into the mixer and thoroughly mixed using a mechanical stirrer until a homogeneous consistency is obtained.

Example 9

A biologically active preparation based on algae - an ultrasonophoresis gel contains 92.67 g (92.67 wt.%) Of an aqueous gel from brown alga Laminaria japonica, 0.01 g (0.01 wt.%) Of Spirulina Platensis alga, 0.01 g (0.01 wt.%) of Fucus vesiculosus CO2 extract, 5.0 g (5.0 wt.%) glycerol, 2.0 g (2.0 wt.%) lanolin, 0.3 g (0.3 wt.%) xanthan, 0.01 g (0.01 wt.%) grape seed oil.

The starting components are loaded into the mixer and thoroughly mixed using a mechanical stirrer until a homogeneous consistency is obtained.

The proposed composition provides the ability to create drugs of different density, sliding ability, drying speed; allows you to create stable emulsions, providing the possibility of using plant extracts in aqueous and oil forms for targeted differentiated effects of drugs.

The resulting gels and masks are easily and evenly applied to the skin, have a high transdermal activity. Due to the physicochemical properties and high biological value, the preparations obtained can have indications for use in cosmetology, thalassotherapy, balneotherapy and physiotherapy, with a wide range of applications in balneological and physiotherapeutic procedures, including hardware methods of exposure (for example, electrophoresis, laser phoresis, magnetophoresis , phonophoresis, etc.).

Claims (2)

1. A biologically active preparation based on algae containing CO2 extracts of medicinal plants, algae, glycerin, characterized in that the preparation contains algae Spirulina Platensis and algae Laminaria japonica in the form of a hydrolyzate, and the extract used is a CO2 extract of medicinal plants selected from the group: Fucus vesiculosus algae extract, horse chestnut extract, ivy extract, ginger extract, grape seed extract, guarana extract, green tea extract, and also contains lanolin, vegetable oil or a mixture of vegetables -negative oils, xanthan in the following ratio, wt. %:
algae hydrolyzate Laminaria japonica 75-98% Algae Spirulina Platensis 0.01-5% CO2 extract of medicinal plants selected from the group: Fucus vesiculosus algae extract, horse chestnut extract, ivy extract, ginger extract, grape seed extract, guarana extract, green tea extract 0.01-10% glycerol 0.01-10% lanolin 0.01-10% vegetable oil or a mixture of vegetable oils 0.01-10% xanthan 0.01-2% 2. The biologically active preparation according to claim 1, characterized in that, as a mixture of vegetable oils, it contains 0.005-0.5% essential oil and 0.005-9.5 stone seed oil.