WO2018066674A1 - Dispositif de mesure, procédé de mesure et programme de mesure - Google Patents

Dispositif de mesure, procédé de mesure et programme de mesure Download PDF

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Publication number
WO2018066674A1
WO2018066674A1 PCT/JP2017/036388 JP2017036388W WO2018066674A1 WO 2018066674 A1 WO2018066674 A1 WO 2018066674A1 JP 2017036388 W JP2017036388 W JP 2017036388W WO 2018066674 A1 WO2018066674 A1 WO 2018066674A1
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WIPO (PCT)
Prior art keywords
blood flow
massage
measurement
measuring
heart rate
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PCT/JP2017/036388
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English (en)
Japanese (ja)
Inventor
孝浩 渡邉
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京セラ株式会社
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Publication of WO2018066674A1 publication Critical patent/WO2018066674A1/fr

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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00—Measuring for diagnostic purposes; Identification of persons
    • A61B5/02—Detecting, measuring or recording pulse, heart rate, blood pressure or blood flow; Combined pulse/heart-rate/blood pressure determination; Evaluating a cardiovascular condition not otherwise provided for, e.g. using combinations of techniques provided for in this group with electrocardiography or electroauscultation; Heart catheters for measuring blood pressure
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00—Measuring for diagnostic purposes; Identification of persons
    • A61B5/02—Detecting, measuring or recording pulse, heart rate, blood pressure or blood flow; Combined pulse/heart-rate/blood pressure determination; Evaluating a cardiovascular condition not otherwise provided for, e.g. using combinations of techniques provided for in this group with electrocardiography or electroauscultation; Heart catheters for measuring blood pressure
    • A61B5/024—Detecting, measuring or recording pulse rate or heart rate
    • A61B5/0245—Detecting, measuring or recording pulse rate or heart rate by using sensing means generating electric signals, i.e. ECG signals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00—Measuring for diagnostic purposes; Identification of persons
    • A61B5/02—Detecting, measuring or recording pulse, heart rate, blood pressure or blood flow; Combined pulse/heart-rate/blood pressure determination; Evaluating a cardiovascular condition not otherwise provided for, e.g. using combinations of techniques provided for in this group with electrocardiography or electroauscultation; Heart catheters for measuring blood pressure
    • A61B5/026—Measuring blood flow
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00—Measuring for diagnostic purposes; Identification of persons
    • A61B5/16—Devices for psychotechnics; Testing reaction times ; Devices for evaluating the psychological state

Definitions

  • the present disclosure relates to a measurement apparatus, a measurement method, and a measurement program.
  • Non-Patent Document 1 a method for adjusting heart rate or blood pressure and improving autonomic nerve balance by applying massage is known (for example, Patent Document 1).
  • Patent Document 2 a technique for promoting blood circulation of a living body by pressurization is also known (for example, Patent Document 2).
  • the blood pressure can be measured by a blood flow sensor attached to the tragus (for example, Patent Documents 3, 4, and 5).
  • a blood flow measuring unit for measuring a blood flow based on scattered light from the test site;
  • a control unit is Calculate blood flow wave height based on the blood flow measured by the blood flow measurement unit, Calculate the heart rate based on the blood flow measured by the blood flow measurement unit, Measure parasympathetic state, The degree of the depression state of the living body is determined based on the change in the blood flow wave height and the heart rate before and after the start of the massage on the living body and the state of the parasympathetic nerve after the start of the massage.
  • One aspect of the measurement method is: Measuring the blood flow based on scattered light from the test site; Calculating blood flow wave height based on the blood flow measured in the blood flow measurement step; Calculating a heart rate based on the blood flow measured in the blood flow measurement step; Measuring the parasympathetic state; A step of determining the degree of depression of the living body based on changes in the blood flow wave height and the heart rate before and after the start of massage on the living body and the state of the parasympathetic nerve after the start of the massage; Is provided.
  • One aspect of the measurement program is: On the computer, Measuring the blood flow based on scattered light from the test site; Calculating blood flow wave height based on the blood flow measured in the blood flow measurement step; Calculating a heart rate based on the blood flow measured in the blood flow measurement step; Measuring the parasympathetic state; A step of determining the degree of depression of the living body based on changes in the blood flow wave height and the heart rate before and after the start of massage on the living body and the state of the parasympathetic nerve after the start of the massage; Is executed.
  • FIG. 2 is a cross-sectional view taken along the line AA in FIG.
  • FIG. 2 is a functional block diagram which shows schematic structure of the measurement system which concerns on one Embodiment.
  • FIG. 6 is a sequence diagram which shows an example of the process which the measurement system which concerns on one Embodiment performs.
  • FIG. 6 is a sequence diagram showing a continuation of FIG. 5.
  • FIG. 1 is an external perspective view of a measurement system S according to an embodiment.
  • FIG. 1 shows an example of a state in which the measuring device 1 is worn on a person.
  • the measuring apparatus 1 is a wearable device that is worn so as to sandwich the tragus of a human right ear or left ear, for example.
  • the person includes, for example, a patient, a subject, a user, and the like.
  • the shape of the measuring device 1 is arbitrary, for convenience of explanation, the shape of the measuring device 1 according to the present embodiment is assumed to be that shown in FIG.
  • the measurement device 1 worn by a person will be described.
  • the measurement device 1 may be used by wearing a living body other than a person, such as an animal.
  • the measurement system S includes a measurement device 1, a terminal device 2, and a massage device 3.
  • the measuring device 1 is connected to the terminal device 2 by wire.
  • the measuring device 1 may be connected to the terminal device 2 by wireless or a combination of wired and wireless.
  • the terminal device 2 is connected to the massage device 3 by wire.
  • the terminal device 2 may be connected to the massage device 3 by wireless or a combination of wired and wireless. A person wearing the measuring device 1 and the massage device 3 operates the terminal device 2.
  • FIG. 2 is a cross-sectional view taken along the line AA in FIG.
  • the measuring device 1 may have a stretchable and flexible material at a position where it comes into contact with the tragus when worn.
  • This material may be, for example, a rubber material such as silicon rubber or natural rubber. This material can prevent the measurement apparatus 1 from compressing the tragus.
  • the measuring device 1 includes a vascular resistance measuring unit 12 and a blood flow measuring unit 13 which will be described later.
  • FIG. 3 is a functional block diagram showing a schematic configuration of the measurement system S.
  • the measuring apparatus 1 includes a control unit 11, a vascular resistance measurement unit 12, a blood flow measurement unit 13, a storage unit 14, and a communication unit 15.
  • the vascular resistance measurement unit 12 includes a light emitting unit 12a and a light receiving unit 12b.
  • the vascular resistance measurement unit 12 is a transmissive sensor that irradiates the light from the light emitting unit 12a to the target and receives the transmitted light of the light irradiated by the light receiving unit 12b.
  • the blood flow measurement unit 13 includes a light emitting unit 13a and a light receiving unit 13b.
  • the blood flow measurement unit 13 is a reflective sensor that irradiates the light from the light emitting unit 13a to the target and receives the reflected light (scattered light) of the light irradiated by the light receiving unit 13b.
  • the control unit 11 controls and manages the entire measuring apparatus 1 including each functional block included in the measuring apparatus 1.
  • the control unit 11 includes a processor such as a CPU (Central Processing Unit) that executes a program that defines a control procedure.
  • the program is stored, for example, in the storage unit 14 or an external storage medium connected to the measurement apparatus 1.
  • the control unit 11 acquires the value of the vascular resistance measured by the vascular resistance measurement unit 12.
  • the control unit 11 calculates the blood flow wave height and the heart rate based on the blood flow measured by the blood flow measurement unit 13.
  • the blood flow wave height is a value calculated by partially correcting the blood flow waveform as will be described later.
  • the measuring device 1 includes at least one processor 11a to provide control and processing capabilities to perform various functions, as will be described in more detail below.
  • At least one processor 11a may be implemented as a single integrated circuit (IC) or as a plurality of communicatively connected integrated circuits ICs and / or discrete circuits. Also good.
  • the at least one processor 11a can be implemented according to various known techniques.
  • the processor 11a includes one or more circuits or units configured to perform one or more data calculation procedures or processes, for example, by executing instructions stored in associated memory.
  • the processor 11a may be firmware (eg, a discrete logic component) configured to perform one or more data computation procedures or processes.
  • the processor 11a may include one or more processors, controllers, microprocessors, microcontrollers, application specific integrated circuits (ASICs), digital signal processors, programmable logic devices, field programmable gate arrays, or the like.
  • ASICs application specific integrated circuits
  • the functions of the control unit 11 described below may be executed including any combination of these devices or configurations, or other known combinations of devices and configurations.
  • FIG. 4A is a diagram illustrating an example of a blood flow waveform measured by using the blood flow measuring unit 13.
  • the vertical direction indicates the blood flow
  • the horizontal direction indicates time.
  • the control unit 11 of the measurement apparatus 1 performs a process of smoothing the waveform as illustrated in FIG. 4B by calculating a moving average for the waveform.
  • the control unit 11 compares the blood flow at an arbitrary time with the blood flow before and after the blood flow. As a result of the comparison, if the former is smaller than the latter, the blood flow volume at the time is set as a minimum value. In FIG. 4, the minimum value is indicated by P2.
  • the control unit 11 determines one pulse from a certain minimum value P2 to the next minimum value P2 ′, and sets the maximum value of the blood flow during one beat as the maximum value. In FIG. 4B, the maximum value is indicated by P1.
  • the control unit 11 can measure the blood flow wave height H by setting the difference between the maximum value and the minimum value of the blood flow volume at a certain beat as the blood flow wave height H.
  • the control unit 11 can also measure the heart rate by calculating the number of beats for a predetermined time.
  • the vascular resistance measurement unit 12 can measure the value of vascular resistance by measuring the light transmittance in the tissue inside the tragus. Specifically, the vascular resistance measurement unit 12 irradiates a human tragus with measurement light, receives transmitted light that has passed through the tissue inside the tragus, and uses a photoelectric conversion signal of the received transmitted light as a biological measurement output. Transmit to the control unit 11.
  • the vascular resistance measurement unit 12 may be configured by a transmission type sensor.
  • the vascular resistance measurement unit 12 may include a light emitting unit 12a and a light receiving unit 12b.
  • the light emitting unit 12 a emits laser light based on the control of the control unit 11.
  • the light emitting unit 12a irradiates, for example, a laser beam having a wavelength capable of detecting a predetermined component contained in blood as a measurement light onto a test site of a human tragus.
  • a laser beam having a wavelength capable of detecting a predetermined component contained in blood as a measurement light onto a test site of a human tragus.
  • an LD laser diode: Laser Diode
  • the light receiving unit 12b receives the transmitted light of the measurement light from the site to be examined.
  • the light receiving unit 12b is configured by, for example, a PD (photodiode: Photo Diode).
  • the vascular resistance measurement unit 12 transmits the photoelectric conversion signal of the transmitted light received by the light receiving unit 12b to the control unit 11 as a biological measurement output.
  • the vascular resistance measurement unit 12 includes two LDs for irradiating a test site with laser beams having two different wavelengths.
  • the light emitting unit 12a includes an LD that emits laser light having a wavelength of about 660 nm and an LD that emits laser light having a wavelength of about 940 nm.
  • the blood flow measuring unit 13 transmits measurement light to the tragus and reflects light from the tragus for the measurement light. Specifically, the blood flow measurement unit 13 irradiates the tragus with measurement light and receives reflected light (scattered light) from the tissue inside the tragus. The blood flow measurement unit 13 transmits a photoelectric conversion signal of the received scattered light to the control unit 11 as a biological measurement output.
  • the blood flow measurement unit 13 may be configured by a reflective sensor.
  • the blood flow measuring unit 13 may include a light emitting unit 13a and a light receiving unit 13b.
  • the light emitting unit 13 a emits laser light based on the control by the control unit 11.
  • the light emitting unit 13a irradiates the test site with laser light.
  • This laser light means the above-described measurement light.
  • the laser beam is, for example, a laser beam having a wavelength that can detect a predetermined component contained in blood.
  • the light emitting unit 13a is configured by, for example, one LD.
  • the light receiving unit 13b receives the scattered light of the measurement light from the test site.
  • the light receiving unit 13b is configured by a PD, for example.
  • the blood flow measurement unit 13 transmits the photoelectric conversion signal of the scattered light received by the light receiving unit 13b to the control unit 11 as a biological measurement output.
  • the control unit 11 measures the blood flow waveform at the site to be examined using the Doppler shift based on the biological measurement output received from the blood flow measurement unit 13.
  • the control unit 11 measures the blood flow height and the heart rate based on the blood flow waveform measured by the blood flow measurement unit 13.
  • the storage unit 14 is composed of a semiconductor memory.
  • the storage unit 14 may be configured with a magnetic memory or the like.
  • the storage unit 14 stores various information and / or programs for operating the measuring apparatus 1.
  • the storage unit 14 also functions as a work memory.
  • the storage unit 14 stores, for example, the blood flow wave height and the heart rate calculated by the control unit 11.
  • the storage unit 14 stores the value of the vascular resistance measured by the vascular resistance measurement unit 12.
  • the communication unit 15 is an interface that transmits and receives information to and from the terminal device 2 and the like via a network.
  • the communication unit 15 may have a communication function by wire, wireless, or a combination thereof.
  • the wired communication function may be USB (Universal Serial Bus) or LAN (Local Area Network).
  • the wireless communication function may be LTE (Long Term Evolution), wireless LAN, infrared communication, or the like.
  • the terminal device 2 is an arbitrary terminal device such as a smartphone, a feature phone, a PC (Personal Computer), or a tablet PC.
  • the terminal device 2 includes a terminal control unit 21, a display unit 22, an input unit 23, and a communication unit 24.
  • the terminal control unit 21 controls and manages the entire terminal device 2 including each functional block of the terminal device 2.
  • the terminal control unit 21 includes a processor such as a CPU that executes a program that defines a control procedure, and the program is stored in, for example, a storage unit of the terminal device 2 or an external storage medium connected to the terminal device 2.
  • the display unit 22 is a liquid crystal display.
  • the display unit 22 may be a display device such as an organic EL display or an inorganic EL display.
  • the display unit 22 can display various information such as a blood flow measurement value obtained by the blood flow measurement unit 13, for example.
  • the input unit 23 receives an operation input from the target.
  • the input unit 23 includes, for example, operation buttons (operation keys).
  • the input unit 23 may be configured by a touch panel, and an operation key that receives an operation input from the target may be displayed on a part of the display unit 22 to receive a touch operation input by the target.
  • the communication unit 24 is an interface that transmits and receives information to and from the measurement device 1 and the massage device 3 via a network. Since the configuration of the communication unit 24 is the same as that of the communication unit 15, the description thereof is omitted. That is, the measuring device 1, the terminal device 2, and the massage device 3 can transmit and receive data and / or control information to each other.
  • the massage device 3 includes a massage unit 31.
  • the massage unit 31 is attached to a person and massages, for example, a person's calf vein in synchronization with the heartbeat.
  • the massage refers to an action such as rubbing a predetermined part, pushing, knob, fist, or hitting, or any combination thereof.
  • the massage includes an action performed by an action performed by using a machine or other object, an action by a person, or an action obtained by combining these actions.
  • Massage applies a predetermined deformation to a predetermined part.
  • the massage unit 31 may start massage based on a start operation by a person on the massage device 3 or may start massage based on a start instruction received from the terminal device 2.
  • the massage device 3 may include a CPU and a semiconductor memory.
  • the CPU controls the entire massage device 3 in cooperation with a program stored in the semiconductor memory.
  • the massage unit 31 includes, for example, at least one roller driven by a motor controlled by a CPU. This roller massages a person's calf vein, for example, in synchronization with the heartbeat.
  • the massage unit 31 may include, for example, an airbag for massaging a human calf vein in synchronization with a heartbeat.
  • the massage unit 31 may have other appropriate configurations.
  • the degree of depression is determined.
  • the unit of blood flow wave height is [ml / min]
  • the unit of vascular resistance is [mmHg / l / min]
  • the unit of heart rate is [beats / min].
  • a method for determining the degree of depression will be described in detail.
  • Depression in the present disclosure refers to a state of feeling depressed. Depressions of the present disclosure can include both conditions diagnosed by a physician and conditions that have not been diagnosed. Depression of the present disclosure can also include so-called depression conditions.
  • the degree of depression in the present disclosure refers to the degree of the depression state.
  • the measuring device 1 is attached to the tragus based on a human operation.
  • the mounting location of the measuring device 1 may be another appropriate location of the human body such as the subject's nose, forehead, arm, or foot.
  • the massage device 3 is attached to a part of a human body (for example, a calf).
  • the terminal device 2 is connected to each of the measuring device 1 and the massage device 3 based on a connection operation by a person.
  • the terminal control unit 21 of the terminal device 2 When the terminal control unit 21 of the terminal device 2 receives a start operation by a person, the terminal control unit 21 transmits an instruction to start measurement of the blood flow rate and blood vessel resistance of the person to the measurement device 1. At this time, the measuring device 1 measures the blood flow based on the biological measurement output from the blood flow measuring unit 13, and the vascular resistance measuring unit 12 measures the value of the vascular resistance.
  • the display unit 22 performs a display that prompts the user to relax and relax. Specifically, the display unit 22 may perform a display that prompts the user to wear an eye mask, or may perform a display that prompts the user to listen to music.
  • the terminal device 2 may output music from the audio output unit of the terminal device 2.
  • the control unit 11 of the measurement device 1 acquires the value of the vascular resistance from the vascular resistance measurement unit 12 at an arbitrary time point before the massage, and the basal (at rest) blood flow rate measured by the blood flow measurement unit 13. Based on the values, the blood flow height and the heart rate are calculated.
  • the vascular resistance, the blood flow wave height, and the heart rate are, for example, a minimum value, an average value, or a maximum value in a predetermined time before the massage. In this way, the control unit 11 acquires values of vascular resistance, blood flow wave height, and heart rate.
  • the control unit 11 stores the acquired values of vascular resistance, blood flow wave height, and heart rate in the storage unit 14 as values before massage.
  • the terminal control unit 21 transmits a massage start instruction to the massage device 3 when it is determined that a predetermined time (for example, 5 minutes) has elapsed since the measurement device 1 started measuring blood flow and vascular resistance.
  • a predetermined time for example, 5 minutes
  • the massage part 31 of the massage apparatus 3 which received the massage start instruction starts a massage.
  • Control unit 11 determines whether massage has started. Whether or not the massage has started is determined in advance by storing in the storage unit 14 a predetermined time from when the measuring device 1 starts measuring the blood flow volume and the vascular resistance until the massage starts. Judgment is made depending on whether or not. As an alternative example, whether or not the massage has started may be determined based on whether or not a notification that the massage has started is received from the terminal device 2.
  • the control unit 11 After starting the massage, the control unit 11 acquires the value of the vascular resistance measured by the vascular resistance measurement unit 12 and calculates the blood flow wave height and the heart rate based on the value measured by the blood flow measurement unit 13.
  • the vascular resistance, blood flow wave height, and heart rate are, for example, a minimum value, an average value, or a maximum value at an arbitrary time after the start of massage. In this way, the control unit 11 acquires values of vascular resistance, blood flow wave height, and heart rate.
  • the control unit 11 stores the acquired values of vascular resistance, blood flow wave height, and heart rate in the storage unit 14 as values after the start of massage.
  • the control unit 11 acquires the values of the vascular resistance, the blood flow wave height, and the heart rate acquired before the massage, and after the massage starts. The respective values of the vascular resistance, blood wave height and heart rate are compared. Specifically, the control unit 11 determines whether or not the values of the vascular resistance, the blood flow wave height, and the heart rate have increased before and after the start of the massage.
  • the control unit 11 transmits a massage end instruction to the massage device 3.
  • condition 1 vascular resistance is decreased, (condition 2) blood flow wave height is increased, and (condition 3) heart rate is decreased before and after the start of massage are satisfied. Determine whether.
  • the controller 11 determines that the degree of depression of the person wearing the measuring device 1 is low. Whether the degree of depression is low or high is determined by comparison with a reference value.
  • the control unit 11 determines whether the parasympathetic nerve of the person wearing the measuring device 1 is dominant. Whether or not the parasympathetic nerve is dominant indicates whether or not the person is in a relaxed state. Whether or not the parasympathetic nerve is dominant is determined using, for example, LF / HF determination that performs frequency analysis on heartbeat or blood pressure fluctuation (spontaneous fluctuation) measured by the vascular resistance measurement unit 12 or the blood flow measurement unit 13. As an alternative, whether the parasympathetic nerve is dominant may be determined using thermography, measurement of skin sympathetic nerve reflex, catecholamine measurement, and the like.
  • the LF / HF determination is based on the heart rate fluctuation time-series data indicating the fluctuation of the heartbeat interval, which is the heartbeat time interval, and the high frequency fluctuation component (HF component) corresponding to the respiratory fluctuation and the Mayer wave (Mayer wave) which is the blood pressure fluctuation. ) Is extracted by comparing the magnitudes of the two components.
  • the control unit 11 acquires a fluctuation of a heartbeat interval that is a time interval of heartbeat from the measured blood flow volume, and performs LF / HF determination.
  • control unit 11 determines that the parasympathetic nerve of the person wearing the measuring device 1 is dominant, the control unit 11 determines that the degree of depression of the person is low.
  • the control part 11 determines whether a person's depression degree is high or low, it will transmit the result to the terminal device 2 as depression degree information.
  • the terminal device 2 that has received the depression degree information displays on the display unit 22 whether the depression degree is high or low.
  • the terminal device 2 may display that there is no massage effect when the degree of depression is high, and may display that there is a massage effect when the degree of depression is low.
  • the measurement system S can determine whether or not the depression state is chronic by determining the degree of depression over a period of several days or the like.
  • a depression degree determination method executed by the measurement system S according to the present embodiment will be described with reference to a sequence diagram shown in FIG.
  • the sequence diagram shown in FIG. 5 starts with the measurement device 1 and the massage device 3 attached to a person who operates the terminal device 2.
  • the terminal device 2 transmits a measurement start instruction to the measurement device 1 based on a start operation by a person (step S1).
  • the measurement apparatus 1 that has received the measurement start instruction measures the blood flow based on the biometric output acquired from the blood flow measurement unit 13 (step S2).
  • the measuring apparatus 1 calculates the blood flow wave height and the heart rate before starting the massage based on the blood flow measured in step S2 (step S3).
  • the measuring apparatus 1 measures the value of vascular resistance in the vascular resistance measuring unit 12 (step S4).
  • the measuring device 1 stores the values of the blood flow wave height and the heart rate calculated in step S3 and the value of the vascular resistance measured in step S4 in the storage unit 14 (step S5).
  • Step S6 When the terminal device 2 determines that a predetermined time (for example, 5 minutes) has elapsed after executing Step S1 (Yes in Step S6), the terminal device 2 transmits a massage start instruction to the massage device 3 (Step S7). The massage device 3 that has received the massage start instruction performs massage (step S8).
  • a predetermined time for example, 5 minutes
  • the measuring device 1 determines whether or not a massage is started (step S9).
  • the measurement apparatus 1 determines that the massage has started (Yes in step S9), based on the blood flow measured based on the biometric output from the blood flow measurement unit 13, the blood flow wave height after the massage starts and The heart rate is calculated (step S10).
  • the measuring apparatus 1 measures the value of vascular resistance in the vascular resistance measuring unit 12 (step S11).
  • the measuring device 1 stores the values of the blood flow wave height and the heart rate calculated in Step S10 and the value of the vascular resistance measured in Step S11 in the storage unit 14 (Step S12).
  • FIG. 6 shows a continuation of the sequence diagram shown in FIG.
  • the measuring apparatus 1 has the respective values of the vascular resistance, blood flow wave height, and heart rate acquired before the start of the massage, and the vascular resistance, blood flow wave height, and heart rate acquired after the start of the massage. Are compared (step S21). Specifically, the measuring apparatus 1 determines whether or not all three conditions (condition 1) vascular resistance is decreased, (condition 2) blood flow wave height is increased, and (condition 3) heart rate is decreased are satisfied. judge.
  • Step S21 determines that the person's degree of depression is low (Step S22).
  • Step S22 determines whether or not the human parasympathetic nerve is dominant (step S23).
  • the measurement device 1 determines that the person's depression degree is low when the answer is Yes in Step S23 (Step S22), and if the answer is No in Step S23, the measurement apparatus 1 determines that the person's depression degree is high (Step S24).
  • the measuring device 1 stores the depression information determined in Step S22 and Step S24 in the storage unit 14 (Step S25).
  • the measuring device 1 transmits the depression degree information to the terminal device 2 (step S26).
  • the terminal device 2 that has received the depression degree information displays the depression degree information (step S27).
  • the measurement apparatus 1 transmits the measurement light, and receives the reflected light of the measurement light to measure the blood flow volume 13 and the control section 11.
  • the control unit 11 calculates the blood flow height based on the blood flow measured by the blood flow measurement unit 13 and calculates the heart rate based on the blood flow measured by the blood flow measurement unit 13.
  • the control unit 11 measures the state of the parasympathetic nerve, and changes the blood flow wave height and heart rate before and after the start of massage for the person and the state of the parasympathetic nerve after the start of massage for the person. Determine the degree. That is, since the control unit 11 determines the person's depression degree based not only on the value calculated based on the blood flow volume but also on the state of the parasympathetic nerve, it can actually determine the person's depression degree appropriately.
  • the control unit 11 satisfies that either the blood wave height does not increase or the heart rate does not decrease before and after the start of massage for the person, and the person after the start of the massage
  • the parasympathetic state is dominant, it is determined that the person's degree of depression is low. That is, since the degree of depression of a person is determined not only based on the value calculated based on the blood flow volume but also on whether the parasympathetic nerve is dominant or not, more accurate determination can be made.
  • the control unit 11 satisfies that either the blood wave height does not increase or the heart rate does not decrease before and after the start of massage for the person, and the person after the start of the massage When the parasympathetic state is inferior, it is determined that the person has a high degree of depression. That is, since the degree of depression of a person is determined not only based on the value calculated based on the blood flow volume but also whether the parasympathetic nerve is inferior or not, the determination becomes more accurate.
  • the control unit 11 determines that the person's degree of depression is low before and after the start of the massage for the person, when the blood flow wave height increases and the heart rate decreases. For this reason, it is possible to more accurately determine whether the person's degree of depression is high or low.
  • the measuring apparatus 1 further includes a vascular resistance measurement unit 12 that measures vascular resistance by measuring permeability.
  • the control unit 11 changes the blood wave height and heart rate before and after the start of massage for the person, the state of the parasympathetic nerve after the start of massage for the person, and the change in vascular resistance before and after the start of massage for the person. Based on the person's depression degree. That is, the measuring device 1 uses the vascular resistance measurement unit 12 using the permeability measurement instead of the blood flow measurement unit 13 for measuring the vascular resistance. Therefore, the vascular resistance can be measured more accurately. Furthermore, the measuring apparatus 1 can more appropriately determine the degree of depression by using the measured value of the vascular resistance for the determination of the degree of depression.
  • control unit 11 does not use the value of the vascular resistance for the determination of the degree of depression, and changes in blood flow wave height and heart rate before and after the start of massage for the person, and parasympathy after the start of massage for the person.
  • a person's depression degree may be determined based on the state of the nerve.
  • the vascular resistance measuring unit 12 measures the vascular resistance
  • the blood flow measuring unit 13 may measure the vascular resistance.
  • the display unit 22 of the terminal device 2 displays the depression degree information
  • the measuring device 1 may include a display unit to display the depression degree information.
  • the measurement apparatus 1 may include an audio output unit, and the depression degree information may be reproduced as audio.
  • the measuring device 1 may include an input unit to accept an input operation by a person. This input operation may be, for example, an instruction to start measurement of blood flow volume and vascular resistance and determination of the degree of depression. If comprised in this way, the person can know his own depression degree by operating only the measuring apparatus 1 without having to connect the measuring apparatus 1 and the terminal apparatus 2.
  • the control unit 11 satisfies the three conditions of (condition 1) vascular resistance decrease, (condition 2) blood flow wave height increase, and (condition 3) heart rate decrease before and after the start of massage. It is determined whether or not it has been done. Next, when it is determined that all the three conditions are satisfied, the control unit 11 determines that the degree of depression of the person wearing the measuring device 1 is low. However, the control unit 11 determines whether or not two conditions of (condition 2) increase in blood flow wave height and (condition 3) decrease in heart rate are satisfied among the three conditions, and the two conditions are satisfied. When it is determined that both of the conditions are satisfied, it may be determined that the person's degree of depression is low. When determining that at least one of the two conditions is not satisfied, the control unit 11 determines whether the parasympathetic nerve is dominant as in the above embodiment.
  • the massage device 3 starts massage 5 minutes after the measurement device 1 starts measuring blood flow.
  • the massage device 3 may start massage immediately after the start of the measurement, or the massage device 3 may start massage at any timing such as 1 to 9 minutes after the start of the measurement.
  • the subject of massage is a person, but this subject may be an animal other than a person.
  • the terminal device 2 and the massage device 3 are connected by wire or wirelessly. However, when the terminal device 2 and the massage device 3 are not connected, the terminal device 2 operates the massage device 3 and massages when a predetermined time has elapsed since the measurement device 1 started measuring blood flow. May be displayed on the display unit 22.
  • control part 11 with which the measuring apparatus 1 produces
  • production of biometric information is It is not restricted to the case where the control part 11 with which the measuring apparatus 1 is provided performs.
  • a server device connected to the measurement device 1 via a wired or wireless network or a combination thereof may include a functional unit corresponding to the control unit 11 and generate biometric information.
  • the measuring device 1 transmits the biometric output acquired by the vascular resistance measuring unit 12 or the blood flow measuring unit 13 from the communication unit 15 to the server device.
  • the server device calculates biometric information based on the biometric information output, and stores the calculated biometric information in the storage unit. As described above, when the server device calculates the biological information and stores the biological information, the measurement device 1 can be reduced in size and the like as compared with the case where all the functional units illustrated in FIG. Can be realized.
  • the measuring device 1 determines the degree of depression.
  • the measuring device 1 may determine a mental state related to the living body other than the degree of depression.
  • massage was performed with respect to a biological body.

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Molecular Biology (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Biophysics (AREA)
  • Pathology (AREA)
  • Cardiology (AREA)
  • Biomedical Technology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Medical Informatics (AREA)
  • Public Health (AREA)
  • Surgery (AREA)
  • Physics & Mathematics (AREA)
  • General Health & Medical Sciences (AREA)
  • Physiology (AREA)
  • Hematology (AREA)
  • Child & Adolescent Psychology (AREA)
  • Developmental Disabilities (AREA)
  • Educational Technology (AREA)
  • Hospice & Palliative Care (AREA)
  • Psychiatry (AREA)
  • Psychology (AREA)
  • Social Psychology (AREA)
  • Signal Processing (AREA)
  • Measuring Pulse, Heart Rate, Blood Pressure Or Blood Flow (AREA)

Abstract

La présente invention concerne un dispositif de mesure comprenant une unité de commande et une unité de mesure de volume d'écoulement sanguin qui mesure un volume d'écoulement sanguin sur la base d'une lumière diffusée à partir d'une zone en cours d'examen, l'unité de commande calculant une hauteur d'onde d'écoulement sanguin sur la base du volume d'écoulement sanguin mesuré avec l'unité de mesure de volume d'écoulement sanguin, calculant une fréquence cardiaque sur la base du volume d'écoulement sanguin mesuré avec l'unité de mesure de volume d'écoulement sanguin, mesurant l'état des nerfs parasympathiques et déterminant le degré d'état dépressif d'un corps vivant sur la base de changements de la hauteur d'onde d'écoulement sanguin et de la fréquence cardiaque avant et après le début d'un massage sur le corps vivant et sur la base de l'état des nerfs parasympathiques après le début du massage sur le corps vivant.
PCT/JP2017/036388 2016-10-05 2017-10-05 Dispositif de mesure, procédé de mesure et programme de mesure WO2018066674A1 (fr)

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Citations (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPH11104090A (ja) * 1997-10-03 1999-04-20 Seiko Epson Corp 心機能診断装置
JP2006136483A (ja) * 2004-11-11 2006-06-01 Nippon Telegr & Teleph Corp <Ntt> 血圧測定器および血圧判定方法
JP2008520311A (ja) * 2004-11-23 2008-06-19 コーニンクレッカ フィリップス エレクトロニクス エヌ ヴィ 鬱病検出装置
JP2011104102A (ja) * 2009-11-17 2011-06-02 Mansankai 健康判定用のｈｒｖ変化検知方法並びに健康判定用のｈｒｖ変化検知装置
JP2012161558A (ja) * 2011-02-09 2012-08-30 Aisin Seiki Co Ltd 心身状態誘導システム
JP2015128579A (ja) * 2013-12-05 2015-07-16 Ｐｓｔ株式会社 推定装置、プログラム、推定装置の作動方法および推定システム

Patent Citations (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPH11104090A (ja) * 1997-10-03 1999-04-20 Seiko Epson Corp 心機能診断装置
JP2006136483A (ja) * 2004-11-11 2006-06-01 Nippon Telegr & Teleph Corp <Ntt> 血圧測定器および血圧判定方法
JP2008520311A (ja) * 2004-11-23 2008-06-19 コーニンクレッカ フィリップス エレクトロニクス エヌ ヴィ 鬱病検出装置
JP2011104102A (ja) * 2009-11-17 2011-06-02 Mansankai 健康判定用のｈｒｖ変化検知方法並びに健康判定用のｈｒｖ変化検知装置
JP2012161558A (ja) * 2011-02-09 2012-08-30 Aisin Seiki Co Ltd 心身状態誘導システム
JP2015128579A (ja) * 2013-12-05 2015-07-16 Ｐｓｔ株式会社 推定装置、プログラム、推定装置の作動方法および推定システム

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