WO2018045582A1 - Moisturising complexing agent-containing hair care composition - Google Patents

Abstract

A hair moisturising complexing agent-containing hair care composition, which in addition to a preservative, a flavouring, a chelating agent, an antioxidant and water, contains (by weight percentage): (A) 0.05%-0.5% of a cationic polymer; (B) 0.5%-3% of a cationic surfactant; (C) 0.5%-10.0% of a fatty alcohol; (D) 0.05%-1% of hydroxyethyl cellulose; (E) 1.0%-20% of a hair moisturising complexing active agent.

Description

[Name of invention established by ISA according to Rule 37.2] A hair care hair care composition containing a moisturizing complex Technical field

The invention belongs to the field of daily chemistry, and in particular relates to a hair care composition containing a high-efficiency hair moisturizing composite active agent.

Background technique

Hair conditioner has been widely used as a hair care conditioner and shampoo. With the acceleration of the segmentation of hair care products, new terms and new usages of various hair care products have emerged, such as from the original hair conditioner to the hair-free hair mask, to the hair mold, to Hair cream, hair spa, etc., all of which are synonymous with hair conditioning conditioners (hereafter referred to as hair conditioners), the difference is reflected in the use of methods, wash or stay, use procedures, apply hair types And the corresponding use effects such as conditioning, etc., one thing in common is that a relatively large amount of silicone oil is used and more or less cationic polymers are used. Therefore, all the products claimed by previous hair care products can be expected to have a smooth conditioning function for wet and dry hair and a surface repair function for damaged hair.

At present, silicone hair conditioning-based hair care technology is very mature in hair care composition technology, and can meet the basic needs of consumers for hair conditioning. However, the so-called maturity of technology is relative, always lags behind people's new demands and the continuous advancement of technology. Therefore, while meeting the basic conditioning needs of hair, people are also focusing on hair conditioning to hair care, from hair care to scalp and hair care. These demands are calling for new hair care technologies and ideas.

According to the prior art, silicone oil, cations and greases are the key technical factors for hair care products. An innovative thinking is that formulators are focusing on the cross-border of skin care and hair care, using skin care concept technology to protect In addition to hair suppleness and conditioning, hair care products also have moisturizing function, permeability to hair and internal and external repair functions for hair scales.

Accordingly, it is an object of the present invention to provide a hair care and hair care composition which utilizes a skin care technique, a synergistic combination of scalp and hair moisturizing effect, synergistically reduces the irritation of the surfactant, and provides multiple dimensions for the scalp and hair. The maintenance of moisturizing factors and the replenishment of moisture improve the dryness of the hair. It also overcomes the shortcomings of previous silicone oil and cationic conditioning hair care technologies.

Summary of the invention

It is an object of the present invention to provide a hair care hair care composition having an efficient moisturizing function.

The hair care hair care composition of the present invention is characterized by, in addition to preservatives, flavors, chelating agents, antioxidants and water, comprising:

(A) a cationic polymer in an amount of 0.05% to 3% by weight of the composition;

(B) a cationic surfactant in an amount of from 0.05% to 10% by weight of the composition;

(C) from 0.5% to 10.0% by weight of the composition of the fatty alcohol thickener and from 0.1% to 3% by weight of the composition of the nonionic cellulose polymer thickener, wherein the fatty alcohol thickener is cetyl wax a mixture of stearyl alcohol (carbon 16/18 alcohol) and behenyl alcohol (carbon 22 alcohol), and carbon 16/18 alcohol: carbon 22 alcohol is mixed in a ratio of 1:1 by weight, and the nonionic cellulose polymer is hydroxyl Ethyl cellulose;

(D) a hair moisturizing complex active agent in an amount of from 1.0% to 15% by weight of the composition, the hair moisturizing complex active agent being composed of the following components;

Hexanediol, which accounts for 10-28% by weight of the composite active agent,

a mixture of sugars of 10-20% by weight of the composite active agent, the sugar mixture is composed of monosaccharides, oligosaccharides and polysaccharides, and the monosaccharide: oligosaccharide: polysaccharide is mixed in a ratio of 5:2:1 by weight. The monosaccharide is fructose and glucose, and the fructose: glucose is mixed in a ratio of 1:1 by weight; the oligosaccharide is sucrose and cyclodextrin, and the sucrose: cyclodextrin is mixed at a weight ratio of 1:0.5; Sodium hyaluronate, having a molecular weight of 400,000 Da to 2.2 million Da;

a water-soluble silicone oil which is 3-20% by weight of the composite active agent, and the water-soluble silicone oil is diethylene glycol-15-methyl ether polydimethylsiloxane;

a mixture of amino acids 5-10% by weight of the composite active agent, the amino acid mixture is composed of alanine, serine, glycine, glutamic acid, cysteine, and alanine: serine: glycine: glutamic acid: half Cystine is mixed at a weight ratio of 1:1:1:0.2:0.1;

Sodium pyrrolidonecarboxylate (PCA sodium), which is 1-5% by weight of the composite active agent;

Hydroxyethyl urea in an amount of 0.5-3% by weight of the composite active agent;

And the balance of water.

The hair care hair care composition of the present invention contains dipropylene glycol in an amount of 10% by weight of the composition.

The hair care hair care composition of the present invention, wherein the cationic polymer is selected from at least one of a cationic cellulose polymer and a cationic guar polymer.

The hair care hair care composition of the present invention, wherein the cationic surfactant is at least one selected from the group consisting of behenyltrimethylammonium chloride and dioctadecyldimethylamine chloride.

The hair care hair care composition of the present invention, wherein the hydroxyethyl cellulose has a viscosity of from 85,000 to 100,000 mPa.s.

The hair care hair care composition of the present invention, wherein the glycine is trimethylglycine.

The hair care hair care composition of the present invention, wherein the sodium hyaluronate has a molecular weight of from 1,000,000 Da to 1.8 million Da.

The shampoo composition of the present invention, wherein the hair moisturizing complex active agent is a hexanediol moisturizing agent, a sodium pyrrolidone carboxylate (PCA sodium) moisturizing agent, a hydroxyethyl urea moisturizing agent, a sugar moisturizing agent, a water-soluble silicone oil moisturizing agent, An amino acid moisturizer and a balance of water; wherein the sugar moisturizer is mixed by a monosaccharide, an oligosaccharide and a polysaccharide in a ratio of 5:2:1 by weight, wherein the monosaccharide is fructose and glucose, and the oligosaccharide For sucrose and cyclodextrin, the polysaccharide is sodium hyaluronate; the amino acid humectant is alanine, serine, glycine, glutamic acid and cysteine in a weight ratio of 1:1:1:0.2:0.1. Mixed, the glycine is trimethylglycine.

Compared with the prior art, the present invention has the following advantages:

The hair care hair care composition of the invention is composed of a composite active agent derived from natural synergistic hair moisturizing action, and the composite active agent is a hexanediol moisturizer containing fructose, glucose, sucrose, cyclodextrin, A sugar moisturizer of sodium hyaluronate containing amino acids of alanine, serine, trimethylglycine, glutamic acid, cysteine It is a multi-dimensional moisturizing ingredient such as nourishing moisturizing ingredients, sodium pyrrolidone carboxylate humectant, hydroxyethyl urea moisturizer, water-soluble silicone oil moisturizer, etc. It has multi-dimensional moisturizing, water-locking and hydrating effects on the scalp and hair. Drying the scalp overcomes the technical drawbacks of the silicone oil and cationic surfactant formulation systems used in previous hair care compositions that focus only on hair surface repair.

Specific embodiment

The selection and action of the components of the present invention are described in detail below.

The shampoo composition of the present invention contains 1-20% by weight of the composition of the hair moisturizing complex active agent, preferably 3% to 15% of the hair moisturizing complex active agent, the hair moisturizing complex active agent is a hexane humectant, A sodium pyrrolidone carboxylate (PCA sodium) humectant, a hydroxyethyl urea moisturizer, a sugar moisturizer, a water-soluble silicone oil moisturizer, an amino acid moisturizer and water; wherein the sugar moisturizer is composed of a monosaccharide, oligomeric a composition of sugar and polysaccharide, wherein the monosaccharide is fructose and glucose, the oligosaccharide is sucrose and cyclodextrin, the polysaccharide is sodium hyaluronate; the amino acid humectant is alanine, serine, glycine, glutamic acid and cysteine Acid composition. The specific composition and activity are as follows:

Between 10-28% by weight of the composite active agent, hexanediol, 10-20% by weight of the composite active agent, the sugar mixture is composed of monosaccharides, oligosaccharides and polysaccharides, and monosaccharide: oligomerization Sugar: Polysaccharide is mixed in a weight ratio of 5:2:1; monosaccharide is fructose and glucose, and fructose: glucose is mixed in a ratio of 1:1 by weight; oligosaccharide is sucrose and cyclodextrin, and sucrose: ring The dextrin was mixed at a weight ratio of 1:0.5, and the polysaccharide was sodium hyaluronate.

a water-soluble silicone oil which is 3-20% by weight of the composite active agent, the water-soluble silicone oil being PEG/PPG-22/23 polydimethylsiloxane; a mixture of amino acids 5-10% by weight of the composite active agent, the amino acid mixture It is composed of alanine, serine, glycine, glutamic acid and cysteine, wherein alanine:serine:glycine:glutamic acid:cysteine in a weight ratio of 1:1:1:0.2:0.1 Mixing ratio; sodium pyrrolidone carboxylate (PCA) humectant, 1-5% by weight of the composite active agent; hydroxyethyl urea humectant, 0.5-3% by weight of the composite active agent;

And the balance of water.

Hair moisturizing complex active agent

Hexanediol. Hexanediol, English name: 2-Methyl-2, 4-pentanediol, Hexylene Glycol. Colorless transparent liquid. Has a mild sweet aroma. Soluble in water, ethanol, ether, low carbon aliphatic hydrocarbons. Used as a solvent, fragrance, medical disinfectant. It is obtained by condensation of acetone to obtain diacetone alcohol, which is obtained by liquid phase hydrogenation. The hexanediol molecular formula C6H14O2, molecular weight, 118.17g / mol, relative density (g / mL): 0.925, can be miscible with water, lower alcohols, ethers, various aromatic hydrocarbons, aliphatic hydrocarbons and the like. Used as a solvent and scalp and hair moisturizer in the present invention.

Carbohydrates, also known as carbohydrates (English: carbohydrate or saccharide), are a general term for polyhydroxy aldehydes or polyhydroxy ketones and their polycondensates and certain derivatives. Because they are composed of carbon, hydrogen and oxygen, they are expressed in chemical formula. Similar to "carbon" and "water" polymerization, it is also called carbohydrate. Carbohydrates are an important class of organic compounds widely distributed in nature. The sucrose consumed daily, the starch in the grain, the cellulose in the plant body, the glucose in the human blood, and the like are all sugars. From the biological function point of view, sugar plays an important role in the process of life activities and is an important energy source in the human body.

Sugar is an important nutrient for the human body. It is mainly divided into monosaccharides, oligosaccharides and polysaccharides, and plays an important role in the human body. In the present invention, monosaccharides, oligosaccharides and polysaccharides are used and mixed in a ratio of 5:2:1 by weight, and the molecular weight is uniformly distributed from bottom to medium to high. The optimized ratio of the monosaccharide, the oligosaccharide and the polysaccharide contained in the invention has a certain moisturizing function and has a good coordinated moisturizing effect on the hair.

Monosaccharide. Monosaccharide: It is the smallest molecule of this type because it cannot be hydrolyzed into smaller carbohydrates. They are some aldehydes or ketones with two or more hydroxyl groups. The unmodified monosaccharide formula can be expressed as: (C〃H2O))n, which is called a "carbohydrate" because it is a multiple of carbon and water molecules. Monosaccharides are an important fuel molecule and a structural fragment of nucleic acids. n=3 in the smallest monosaccharide, namely: dihydroxyacetone or D- and L-glyceraldehyde, and so on, triose (glyceraldehyde); pentose, five-carbon sugar such as: ribose, deoxyribose; Sugars such as: glucose, fructose (chemical formula are C6H12O6), glucose is pyranose, and fructose is furanose.

The monosaccharide in the present invention is fructose and glucose.

Fructose (C6H12O6) is a simple sugar (monosaccharide) that is very soluble in water and is found in many foods. Together with glucose and galactose, it constitutes the three main components of blood sugar. Honey, fruit on the tree, berries, melons, And some root vegetables such as: beets, sweet potatoes, European radishes, onions, etc. contain fructose; fructose molecules are smaller than sucrose, and also a product of sucrose decomposition, sucrose is a disaccharide, due to the catalytic properties of the enzyme during digestion Decomposed into a glucose and a fructose. Fructose is a polyhydroxy ketose, molecular formula: CH2OH (CHOH) 3C = OCH2OH, molecular weight: 180.16, water solubility: 3750g / L (20 ° C), in sugars, fructose is the most hygroscopic, easy to absorb water. Fructose is a monosaccharide, the molecule is smaller than sucrose, the osmotic pressure is twice as high as that of sucrose, it can penetrate cell tissue faster, the solubility is high, and the diffusion rate is fast in water. Therefore, fructose application and hair products have good penetration into hair. Sexual moisturizing function.

Glucose (chemical formula C6H12O6), white crystal or granular powder, also known as corn sugar, maize, or abbreviated as glucose. Unlike fructose, glucose is a polyhydroxy aldose, so it is also called reducing sugar. Its molecular formula: CH2OH(CHOH)4CHO, molecular weight: 180.16, is an indispensable nutrient for metabolism in living organisms. It is the most widely distributed and most important one in nature. Single sugar. Glucose, chemical name: 2,3,4,5,6-pentahydroxyhexanal, glucose plays an important role in the biological field, is the energy source of living cells and metabolic intermediates, that is, the main energy-supplying substances of organisms, their physics Characteristics: white crystal, soluble in water, sweet, melting point 146 ° C, containing five hydroxyl groups, one aldehyde group, with the properties of polyol and aldehyde. It is hygroscopic, soluble in water and has a moisturizing function.

Oligosaccharides, also known as oligosaccharides (oligosaccharide; oligosaccharides; oligose), are compounds containing 2-10 glycosidic bonds, which can be used as a monosaccharide glycosidic hydroxyl group and another single A certain hydroxyl group of sugar is formed by shrinkage. They are often covalently bound to proteins or lipids, in the form of glycoproteins or glycolipids. Oligosaccharides usually form 2 to 4 monosaccharides by glycosidic bonds to form small aggregates, which include functional oligosaccharides and common oligosaccharides. The most common oligosaccharides are disaccharides, also known as disaccharides. Two monosaccharides are formed by glycosidic bonds, and the types of covalent bonds connecting them are mainly two major types: N-glycan linkage and O-glycosidic linkage. 1N-glycosidic bond: The oligosaccharide chain is linked to the amino group of Asn on the polypeptide. There are three main types of such oligosaccharide chains: high mannose, heterozygous and complex. In the 2O-glycosidic bond type, the oligosaccharide chain is linked to the hydroxyl group of Ser or Thr on the polypeptide chain or to the hydroxyl group of the membrane lipid. There are oligosaccharides in foods such as garlic, onions, burdock, asparagus, beans, and honey. Oligosaccharides Extracted from natural plants, it can also be synthesized by using biochemical technology and enzyme reaction, using starch and disaccharide (such as sucrose). Common oligosaccharides such as malto-oligosaccharide glucose (α-1,4 glycosidic bond), isomalto-oligosaccharide glucose (α-1,6-glycosidic bond) anti-caries, promote bifidobacterial proliferation, ring paste Fine glucose (cyclic α-1,4 glycosidic bond) has a low caloric value to prevent cholesterol accumulation, and gentian disaccharide glucose (β-1,6 glycosidic bond) bitter taste can form a packaged joint, coupling sugar (Coup ling sugar) Glucose (α-1,4 glycosidic bond), sucrose anti-caries, fructose oligomeric candy (β-1,2 glycosidic bond), sucrose promotes bifidobacterial proliferation, panose glucose (α-1,6 glycoside) Bond combination), fructose anti-caries, trehalose glucose (α-1,1 glycosidic bond), fructose anti-caries, high-quality sweetness, sucrose oligosaccharide glucose (α-1,6 glycosidic bond), sucrose and other anti-caries Promote the proliferation of bifidobacteria, bovine milk oligosaccharide galactose (β-1,4-glycosidic bond), glucose skeleton anti-caries, promote the proliferation of bifidobacteria, chitosan oligosaccharide acetylglucosamine (β-1,4 glycoside Bond binding), sucrose anti-tumor, soy oligosaccharide galactose (α-1,6 glycosidic bond), sucrose Promote the proliferation of bifidobacteria, galactose oligosaccharide galactose (β-1,6 glycosidic bond), sucrose promotes the proliferation of bifidobacteria, fructose-type oligosaccharide galactose (α-1,2':β-1' , 2 glycosidic bond binding) high quality sweet taste, wood oligosaccharide xylose (β-1,4 glycosidic bond binding) water activity regulation.

The oligosaccharides of the invention employ sucrose and cyclodextrin.

Sucrose is the main product of photosynthesis. It is widely distributed in plants, especially in sugar beet, sugar cane and fruit. The white sugar and brown sugar that are usually eaten are sucrose. Sucrose is formed by dehydration condensation of a molecule of glucose and a molecule of fructose with a molecular weight of 342.3. Molecular formula: C12H22O11, density 1.5805, melting point 190-192 º C, specific optical rotation 67 º (C = 26, IN WATER 25 º C), water soluble 1970G / L (15 º C).

Cyclodextrin is a cyclic oligomeric glucose. In general, cyclodextrin is a crystal which is cyclically linked by 6, 7 or 8 glucose units through α, 1-4 bonds, and is called α-, β- or γ-cyclodextrin, respectively. --cyclodextrin: CAS No.: 51211-51-9, molecular formula: C36H60O30, molecular weight: 972.8436, relative density: 1.624 g/cm3, appearance: white crystalline powder, melting point: 278 ° C, water solubility: 145 G / L (25 °C). The cyclodextrin has a cavity at the center of the ring structure, and has an oxygen atom bonded to the glucose oxime inside the carbon-hydrogen bond, which is sulfur-containing, and the grape The hydroxyl groups at the 2nd, 3rd and 6th positions of the sugar are hydrophilic, that is, they exhibit the hydrophobicity and internal hydrophilicity, and the other molecules can be synthesized into the inclusion by weak van der Waals force. There are many substances that can be encapsulated by cyclodextrin, such as dyes, perfumes, drugs, foods, pesticides and preservatives. After the inclusion, the stability, volatility, solubility, and reactivity were all improved. This special role of cyclodextrin makes it an inclusive material with a wide range of applications. For example, in the pharmaceutical industry, the use of cyclodextrin and drug-forming inclusions (encapsulation) can make (1) Stable drug stabilization (2) deliquescence, adhesion or liquid drug pulverization (3) poorly soluble or insoluble drug solubilization (solubilization), etc.; improve the stability of the encapsulated active ingredients; also available in cosmetic manufacturing Cyclodextrin is used as an emulsifier and quality improver. The cyclodextrin (α-cyclodextrin) in the present invention functions as a moisturizing and solubilizing agent.

Polysaccharide. Polysaccharide is a polymer compound obtained by polymerizing 10 or more monosaccharide molecules or derivatives thereof through glycosides, and a polymer obtained by condensing a plurality of monosaccharide molecules or derivatives thereof, also called a polysaccharide. . Can be divided into two types of homopolysaccharides and heteropolysaccharides. A polysaccharide formed by condensation of a monosaccharide is called a homopolysaccharide such as starch, cellulose or the like. A polysaccharide formed by condensation of two or more kinds of monosaccharides or derivatives thereof is called a heteropolysaccharide, such as hyaluronic acid, chondroitin sulfate, etc.; according to the presence or absence of a branch in the sugar molecule, it is classified into a linear polysaccharide and a branched polysaccharide; The difference is divided into structural polysaccharides, storage polysaccharides, antigen polysaccharides, etc.; according to its distribution, it is further divided into extracellular polysaccharides and intracellular polysaccharides.

The polysaccharide of the present invention is selected from the group consisting of chondroitin sulfate and hyaluronic acid, preferably hyaluronic acid.

Chondroitin sulfate (CS), extracted from shark, bovine, porcine, and chicken cartilage, is a class of glycosaminoglycans covalently linked to proteins to form proteoglycans. Chondroitin sulfate is widely distributed in the extracellular matrix and cell surface of animal tissues. The sugar chain is composed of alternating glucuronic acid and N-acetylgalactosamine (also known as N-acetylgalactosamine) disaccharide units through a sugar-like substance. The linker region is attached to the serine residue of the core protein. Chondroitin sulfate: As a mucopolysaccharide, CHONDROITIN SULFATE SODIUM is most common. Chondroitin sulfate is white or off-white powder, odorless, hygroscopic, viscous in aqueous solution, non-condensable by heating, soluble in water, insoluble in organic solvents such as ethanol, acetone, and ether, and its salt is hot. It is relatively stable and will not be damaged if it is heated to 80 °C. An aqueous solution of chondroitin sulfate that is unstable when subjected to higher temperatures or acids, mainly deacetylated or degraded into monosaccharides or A polysaccharide with a smaller molecular weight. The chondroitin sulfate of the present invention is sodium chondroitin sulfate, which has the functions of beauty and anti-aging, and improves the dryness of the skin and hair.

Sodium hyaluronate, also known as sodium hyaluronate, sodium hyaluronate, sodium aldate, is a substance extracted from the cockscomb. It can also be obtained by fermentation of lactic acid bacteria. It is white or off-white granules or powder, and has no odor. When dry. The nitrogen content is 2.8%-4.0%, and the glucuronic acid content is 37.0%-51.0%. Hyaluronic acid is a polymer of a polymer. It is a high-grade polysaccharide composed of the unit D-glucuronic acid and N-acetylglucosamine. D-glucuronic acid and N-acetylglucosamine are linked by a β-1,3-glycosidic bond, and the disaccharide units are linked by a β-1,4-glycosidic bond. The number of disaccharide units can reach as much as 25,000. The molecular weight of hyaluronic acid in the body ranges from 5,000 to 20 million Daltons. Molecular formula: (C14H21NO11)n, hyaluronic acid is an acid mucopolysaccharide. In 1934, Meyer, a professor of ophthalmology at Columbia University in the United States, first isolated the substance from the vitreous of the bovine eye. Hyaluronic acid is a mistranslation. The hyal of RESTIAID hyaluronic acid means Like glass, bright and transparent, and uronic acid refers to uronic acid, hyaluronic acid has nothing to do with uric acid). Hyaluronic acid displays various important physiological functions in the body with its unique molecular structure and physicochemical properties, such as lubricating joints, regulating the permeability of blood vessel walls, regulating protein, water and electrolyte diffusion and operation, and promoting wound healing. It is especially important that the hyaluronic acid molecule contains a large amount of carboxyl groups and hydroxyl groups, which can form hydrogen bonds with water and has a strong water-incorporating ability. It is the best moisture-retaining substance found in nature, and is currently found in nature. The most moisturizing substance is called the ideal natural moisturizing factor (NMF). For example, a 2% pure hyaluronic acid aqueous solution can firmly maintain 98% moisture. Hyaluronic acid is a multifunctional substrate, and hyaluronic acid (hyaluronic acid) HA is widely distributed in various parts of the human body. The skin also contains a lot of hyaluronic acid. The process of human skin maturity and aging also changes with the content of hyaluronic acid and metabolism. It can improve the skin's nutrient metabolism, make the skin soft, smooth, wrinkle-free, increase elasticity, prevent aging, and at the same time be good at moisturizing. Skin absorption enhancer. Used in combination with other nutrients, it can promote the absorption of nutrients. Hyaluronic acid can be used in cosmetic creams, creams, honey, milk, masks, shampoos, etc. to keep skin and hair moist and moisturized. Skin, hair, increase shine, and prevent skin clefts and wrinkles. The polysaccharide of the present invention is chondroitin sulfate, sodium hyaluronate, preferably sodium hyaluronate. The molecular weight of sodium hyaluronate of the invention is 400,000 Daoer Up to 2.2 million Daltons, and further optimized to 1 million Daltons to 1.8 million Daltons, the sodium hyaluronate of the present invention acts as a film and moisturizing hair.

Water soluble silicone oil

A polyether-modified polydimethylsiloxane copolymer which has good water solubility due to its coexistence of a silicone skeleton and a hydrophilic group, and has a mild odor, excellent temperature and light stability, and a formulation The polar ingredients are very compatible, providing a gentle, refreshing and silky skin feel, and moisturizing the skin and hair with strong binding to water molecules, moisturizing, foam stable, emulsified It acts as a hair conditioning conditioner to provide a moisturizing and silky smooth feel to the hair. For example, Dow Corning's DC-193, INCI is named PEG/PPG-22/23 polydimethylsiloxane; Wacker Chemical's DMC6038, INCI is named diethylene glycol-15-methyl ether polydimethylsiloxane Oxygenane and DMC6031 of Wacker Chemical, NICI is named polyethylene glycol/polypropylene glycol-25/25 polydimethylsiloxane. The water-soluble silicone oil of the present invention is selected from Wacker Chemical DMC 6038, which is diethylene glycol-15-methyl ether polydimethylsiloxane.

Amino acid

Hot dyeing, hot air blowing, frequent use of poor shampoo, dry weather and other problems cause the scales to be damaged, the protein inside the hair is lost, causing the hair to become hairy, no stretch, difficult to organize. Amino acid is a natural structure of moisturizing ingredients, vitamin-like substances. Amino acids have a good affinity for hair, which can fill the voids in the hair and restore the hair. The amino acid used in the present invention is a moisturizing agent for hair. We know that alanine can be used for moisturizing hair, arginine can improve the hydrophobicity of hair surface layer, serine and glutamic acid can replenish hair moisture, and glycine enhances moisturizing. Sex and antistatic properties, cysteine and histidine can improve hair toughness and so on. The amino acids contained in the present invention such as arginine, aspartic acid, glycine, alanine, serine, valine, threonine, isoleucine, histidine, phenylalanine, glutamic acid, Cysteine and the like. Alanine, glutamic acid, serine, glycine and cysteine are preferred in the present invention.

Alanine. Alanine is the basic unit of protein and one of the 20 amino acids that make up human proteins. There are two isomers of α-alanine and β-alanine, and β-alanine is pure white prismatic crystal, melting point 200 ° C, relative density 1.437 (19 ° C), molecular weight 89.09, dissolved in water, slightly soluble in methanol and ethanol, insoluble in ether and acetone. The β-alanine of the present invention is a humectant.

Glutamate. Glutamate is an acidic amino acid. The molecule contains two carboxyl groups, the chemical name is α-aminoglutaric acid, the molecular formula: C5H9NO4, appearance: white or colorless scaly crystal, sublimation point: 200 ° C, decomposition point: 247 ˉ 249 ° C, density: 1.538, solubility (water ): 7.5 g / L, molecular weight: 147.113076. The glutamic acid of the present invention is a humectant.

Serine. Serine, also known as beta-hydroxyalanine, is a non-essential amino acid rich in eggs, fish, and soybeans. The human body can also synthesize serine from glycine, which plays a role in the metabolism of fats and fatty acids and the growth of muscles. Because it helps in the production of immune hemoglobin and antibodies, serine is also required to maintain a healthy immune system. Serine plays a role in the production and processing of cell membranes, the synthesis of muscle tissue and sheaths surrounding nerve cells. Serine is a white crystal or crystalline powder with a slightly sweet taste, soluble in water and formic acid, and insoluble in ethanol and ether. The serine of the present invention is a hair nourishing ingredient.

Glycine. Also known as glycine, it is a non-essential amino acid in the human body. Abbreviation: Gly glycine is the simplest structure in the amino acid series. It is an essential amino acid in the human body. It has both acidic and basic functional groups in the molecule. It is ionizable in water and has strong hydrophilicity. It is a polar amino acid. It is soluble in polar solvents, but is insoluble in non-polar solvents, and has a high boiling point and melting point. Glycine can exhibit different molecular forms by adjusting the acidity and alkalinity of the aqueous solution. The glycine of the invention is trimethylglycine, also known as betaine, and is a good moisturizer, antistatic agent, thickener and viscosity control agent. Trimethylglycine chemical formula C5H11NO2, molecular formula C5H11NO2, molecular weight 117.15, solubility: 160g / 100G water.

Cysteine. Alias include: 2-amino-3-mercaptopropionic acid, β-mercapto-α-aminopropionic acid, 3-mercaptoalanine; thioserine, L-cysteine, L-mercaptoalanine. Cysteine is a physiologically functional amino acid. It is the only amino acid of the more than 20 kinds of amino acids that make up the reducing group (-SH). It has been widely used in medicine, food additives and cosmetics. Cysteine molecular formula: C3H7NO2S, molecular weight: 121.15, Solubility in water: 277.433g / L (25 ° C, water), solubility,: soluble in dilute mineral acid and alkaline solution, not soluble in water, insoluble in ethanol, insoluble in ether and chloroform. Cysteine repairs hair and enhances the toughness of the hair.

Sodium pyrrolidonecarboxylate (sodium PCA). Sodium pyrididonecarboxylate, chemical name L-pyridinone-5-carboxylate, abbreviated as L-PCA-Na (PCA sodium), molecular weight: 151.1. Sodium pyridinone carboxylate is a natural moisturizing factor moisturizing As a moisturizing ingredient, it is one of the important components of the body's moisturizing factor. PCA sodium has the function of shrinking and moisturizing the scalp and hair, strengthening the structure of the hair, moisturizing and protecting the color.

Hydroxyethyl urea. Hydroxyethyl urea is a chemical substance with the molecular formula C3H8N2O2, CAS#: [2078-71-9], molecular weight: 104.11, appearance: colorless to pale yellow transparent liquid, pH (10% aqueous solution): 6.0-10.0, Solid content%: 48.0 ˉ 52.0 conductivity (10% aqueous solution): <150, urea (wt%): <1%. It is widely used as a moisturizing agent in skin care moisturizing products. In the present invention, the function of hydroxyethyl urea is to repair the damaged part of the hair and provide moisturizing nourishment, and also has a certain moisturizing property to the scalp.

Cationic polymer. The cationic polymer of the hair care composition of the present invention, for example, the guar polymer is guar hydroxypropyltrimonium chloride. The guar hydroxypropyltrimonium chloride is a pale yellow powder, which is a product obtained by quaternizing guar gum. The guar hydroxypropyltrimonium chloride has a degree of substitution of 0.1-0.2 and a nitrogen content of 1.3-1.7%; other cationic polymers suitable for use in the present invention are hydroxyethyl cellulose and alkyl three. The copolymer of methyl ammonium chloride is classified into three types according to the degree of cationic substitution: high cationic substitution degree JR, medium cationic substitution degree LR and low cationic substitution degree LK, and the medium cationic substitution degree is preferable. The cationic polymer of the present invention is selected from at least one of a cationic cellulose polymer and a cationic guar polymer; the cationic polymer of the present invention comprises 0.05% to 3% by weight of the composition of the present invention, preferably 0.05% to 0.5%. %.

Cationic surfactant. The cationic surfactant of the hair care composition of the present invention is an alkyl quaternary ammonium surfactant such as cetyltrimethylammonium chloride, octadecyltrimethylammonium chloride or docosane. At least one of trimethylammonium chloride, dioctadecyldimethylammonium chloride, dihexadecyldimethylammonium chloride, and cetylmethylammonium chloride. Other alkyl quaternary ammonium salts suitable for use in the present invention are: dodecyldimethylbenzylammonium chloride, ten Octaalkylbenzylammonium chloride, coconut fatty trimethylammonium chloride, oleate trimethylammonium chloride, tallow trimethylammonium chloride, dodecyldimethyl chloride Ammonium, dicocoyl dimethyl ammonium chloride, bis-fat dimethyl ammonium chloride, double hydrogenated tallow dimethyl ammonium chloride, and the like. The cationic surfactant of the composition of the present invention is selected from one of dodecyltrimethylammonium chloride and dioctadecyldimethylammonium chloride. The cationic surfactants of the present invention comprise from 0.05% to 10% by weight of the composition, optimized to be from 0.5% to 3% by weight of the composition.

Thickener. Thickeners suitable for use in cosmetics include inorganic salts, surfactants, water-soluble polymers, and fatty alcohol fatty acids. The thickener achieves the purpose of thickening the system by forming a rod-shaped micelle with a surfactant, forming a three-dimensional hydration network structure with water, or using its own long-chain structure of a macromolecule.

The formulator usually considers the rheological morphology of the final product of the formulation. The rheological morphology of the fluid is divided into Newtonian fluid and non-Newtonian fluid. The Newtonian fluid is the fluid whose shear stress is proportional to the shear rate. Non-Newtonian fluid There are also pseudoplastic fluids, plastic fluids and expanding fluids. Both pseudoplastic fluids and plastic fluids are shear-thinning fluids, but plastic fluids have yield values. The expanding fluid is a shear thickened fluid. To adjust the rheology of the product, the formulator adds a thickener to the formulation for the purpose. Appropriate rheological morphology can give the product an aesthetic, easy to use and produce, and has a certain impact on the stability of the formulation. The rheological morphology of some products even plays a large role in the use of the product. For most paste-shaped cosmetics, the thixotropy of the product is required, because it is required to maintain a good shape during extrusion, under the action or external force. Can be thinned and dispersed. Thickeners are simply a class of substances that increase the viscosity or consistency of a formulation. Thickeners are not added in large amounts, but can greatly increase the viscosity or consistency of the product.

Thickeners used in hair care products are classified into electrolytes, alcohols, amides, carboxylic acids, esters, water-soluble polymers, and the like in terms of chemical properties and application properties.

Electrolytes such as inorganic salts such as sodium chloride and ammonium chloride form micelles in aqueous solution in the presence of surfactants. The presence of electrolytes increases the number of associations of micelles, resulting in the conversion of spherical micelles to rod-shaped micelles, resulting in motion resistance. Increase to increase the viscosity of the system. However, when the electrolyte is excessive, it will affect the structure of the micelle and reduce the resistance to movement, thereby reducing the viscosity of the system. This is called "salting out". Therefore, the amount of electrolyte added generally accounts for the weight percent of the composition. About 1%, and combined with other types of thickeners to make the system more stable.

Alcohols, carboxylic acids such as fatty alcohols and fatty acids are polar organics because they have both lipophilic and hydrophilic groups, some of which are present on the surface tension of the surfactant, Micelle concentration and other properties have a significant effect, the size of the effect increases with the lengthening of the carbon chain, the principle of action is that fatty alcohols, fatty acids can be inserted into the surfactant micelles, promote the formation of micelles, and because of the polarity There is a strong interaction between the molecules of the organic substance and the surfactant, such as the hydrophobic interaction between the hydrocarbon chains and the hydrogen bonding between the polar heads, so that the two molecules are closely aligned on the surface, which greatly changes the surfactant glue. The nature of the bundle reaches the effect of thickening. Commonly used in hair care products are fatty alcohols such as lauryl alcohol, myristyl alcohol, C12-15 alcohol, C12-16 alcohol, decyl alcohol, hexanol, octanol, cetyl alcohol, stearyl alcohol, cetyl stearin. Alcohol (carbon 16/18 alcohol) behenyl alcohol (carbon 22 alcohol) and the like.

Alkanolamides include coconut oil diethanolamide, coco monoethanolamide, coco monoisopropanolamide, cocamide, lauroyl-linoleoyl diethanolamide, lauroyl-myristyl diethanolamide, iso-hard Lipid diethanolamide, linoleic diethanolamide, soybean meal diethanolamide, soybean meal monoethanolamide, oil diethanolamide, palm monoethanolamide, castor oil monoethanolamide, sesame diethanolamide, soybean diethanolamide, stearic acid Ethanolamide, stearic acid monoethanolamide, stearic acid monoethanolamide stearate, stearic acid amide, tallow monoethanolamide, wheat germ diethanolamide, PEG (polyethylene glycol)-3 lauramide, PEG-4 oil Amide, PEG-50 tallowamide, etc.

Ethers such as cetyl polyoxyethylene (3) ether, iso-cetyl polyoxyethylene (10) ether, lauryl polyoxyethylene (3) ether, lauryl polyoxyethylene (10) ether, and Poloxamer-n ( Ethoxylated polyoxypropylene ether) (n=105, 124, 185, 237, 238, 338, 407), etc., esters include PEG-80 glyceryl tallow ester, PEG-8PPG (polypropylene glycol)-3 Isostearate, PEG-200 hydrogenated glyceryl palmitate, PEG-n (n=6, 8, 12) beeswax, PEG-4 isostearate, PEG-n (n=3, 4, 8 , 150) distearate, PEG-18 glyceryl oleate/cocoate, PEG-8 dioleate, PEG-200 glyceryl stearate, PEG-n (n=28, 200 Glyceryl tallow ester, PEG-7 hydrogenated castor oil, PEG-40 jojoba oil, PEG-2 laurate, PEG-120 methyl glucose dioleate, PEG-150 pentaerythritol stearate, PEG-55 propylene glycol oleate, PEG-160 sorbitan triisostearate, PEG-n (n=8, 75, 100) stearate, PEG-150/mercapto/SMDI copolymer (poly Glycol-150/mercapto/methacrylate PEG-150/stearyl/SMDI copolymer, PEG-90 isostearate, PEG-8/PPG-3 dilaurate, cetyl palmitate, cetyl palmitate, C18-36 acid Ethylene glycol ester, pentaerythritol stearate, pentaerythritol, propylene glycol stearate, behenyl ester, cetyl ester, glyceryl tribehenate, glyceryl trihydroxystearate, and the like.

Water-soluble polymers such as 1, cellulose: cellulose, cellulose gum, carboxymethyl hydroxyethyl cellulose, cetyl hydroxyethyl cellulose, ethyl cellulose, hydroxyethyl cellulose, hydroxypropyl Cellulose, hydroxypropyl methylcellulose, methylcellulose, carboxymethylcellulose, etc.; 2, polyoxyethylenes such as PEG-n (n=5M, 9M, 23M, 45M, 90M, 160M) Wait.

The thickening mechanism of the water-soluble cellulose polymer is that the hydrophobic main chain is associated with the surrounding water molecules through hydrogen bonding, which increases the fluid volume of the polymer itself and reduces the space for the particles to move freely, thereby improving the viscosity of the system. It is also possible to achieve an increase in viscosity by entanglement of molecular chains, which is characterized by high viscosity in static and low shear and low viscosity in high shear. This is because at the static or low shear rate, the cellulose molecular chain is in a disordered state and the system exhibits high viscosity; at high shear speed, the molecules are arranged in parallel with the flow direction, and are easy to slide each other, so the system The viscosity is reduced. 3. Polyacrylic acid such as acrylate/C10-30 alkyl acrylate crosspolymer, acrylate/hexadecylethoxy (20) itaconate copolymer, acrylate/hexadecyl B Oxylate (20) methacrylate copolymer, acrylate/tetradecyl ethoxy (25) acrylate copolymer, acrylate/octadecyl ethoxy (20) itaconate copolymer, Propylene ester / octadecyl ethoxy (20) methacrylate copolymer, acrylate / octadecyl ethoxy (50) acrylate copolymer, acrylate / VA crosslinked polymer, PAA ( Polyacrylic acid), sodium acrylate/ethylene isocyanate cross-linked polymer, Carbomer (polyacrylic acid) and its sodium salt, etc., thickening mechanism of polyacrylic thickener is thickener dissolved in water, through carboxylate ion The same-sex electrostatic repulsion, the molecular chain extends from a spiral to a rod, thereby increasing the viscosity of the aqueous phase. 4. Natural rubber and its modified substances such as alginic acid and its (ammonium, calcium, potassium) salt, pectin, sodium hyaluronate, guar gum, cationic guar gum, hydroxypropyl guar gum, jaundice Glue, carrageenan and its (calcium, sodium) salt, xanthan gum, sclerotium gum, etc. 5, inorganic polymers and their modifications such as magnesium aluminum silicate, silicon dioxide, sodium magnesium silicate, hydration Silica, montmorillonite, bentonite, lithium magnesium silicate, hectorite, stearic ammonium montmorillonite, stearic ammonium hectorite, distearyl ammonium montmorillonite, quaternary ammonium salt-90 Montmorillonite, quaternary ammonium salt-18 Soil, quaternary ammonium salt-18 hectorite, etc. Inorganic thickener, such as bentonite, is a layered silicate which swells to form a flocculent substance after absorption, has good suspension and dispersibility, and combines with an appropriate amount of water to form a gelatinous body, which can release charged particles in water. Increase the viscosity of the system.

The hair care and hair care composition of the present invention, the thickener is preferably a fatty alcohol and a water-soluble polymer, wherein the fatty alcohol is cetearyl alcohol (carbon 16/18 alcohol) and behenyl alcohol (carbon 22 alcohol). Mixture, and carbon 16/18 alcohol: carbon 22 alcohol is mixed in a ratio of 1:1 by weight; fatty alcohol accounts for 1% to 10% by weight of the composition of the invention; water-soluble polymer thickener is water-soluble non-aqueous Ionic cellulose polymer. The water soluble nonionic cellulosic polymers of the present invention are thickeners and conditioning agents. Such cellulosic polymers comprise hydroxyethyl cellulose and hydroxypropyl methylcellulose, with hydroxyethyl cellulose being preferred. Hydroxyethyl cellulose is prepared by etherification of base cellulose and ethylene oxide or chlorohydrin. Hydroxyethyl cellulose has different grades, each with different viscosity and degree of substitution, and different viscosity ranges. The degree of substitution of the glucose unit hydroxyethyl group is from 1.4 to 2.0. The average molecular weight of hydroxyethyl cellulose ranges from 80.000 to 900.000. It belongs to nonionic soluble cellulose ethers. Hydroxyethyl cellulose of the invention, such as American water-soluble hydroxyethyl cellulose

250, American Dow Hydroxyethyl Cellulose HEC QP-100MH, the hydroxyethyl cellulose of the invention adopts American Dow Hydroxyethyl Cellulose HEC.OP-100MH. The viscosity is 85000-100000 mpas (Brookfield RV Viscometer), High viscosity grade hydroxyethyl cellulose is pseudoplastic, the solution will become thinner under shear, and the paste must be thick when poured out of the container, but it needs to be changed when rubbed on the hand and applied to the hair. It is thin, moist and easy to disperse. The hydroxyethyl cellulose is present in the composition of the invention in a weight ratio of from 0.05% to 3.0%, preferably from 0.1% to 1%.

A cosmetically acceptable carrier. The polydimethylsiloxane, the hair care hair care composition of the present invention may comprise from 0.05% to 6.0%, preferably from 0.5% to 5.0%, by weight of the composition of polydimethylsiloxane, said polydimethylsiloxane The oxane is a non-volatile polydimethylsiloxane having a viscosity of 50 cs to 300,000 cs. Other polydimethylsiloxanes suitable for use in the present invention include modified polydimethylsiloxanes such as amino-modified polydimethylsiloxane and polyether-modified polydimethylsiloxane.

Polyol, the polyol of the hair care composition of the present invention may be propylene glycol, dipropylene glycol, polyethylene glycol, 1,3-butanediol, sorbitol, glycerin (glycerin) or the like. The polyol in the hair care hair care composition of the present invention is dipropylene glycol. Ben The dipropylene glycol in the invention is mainly used to dissolve the preservative used in the present invention and to dissolve and synergize. In the present invention, dipropylene glycol is 10% by weight of the composition, optimized to 5% by weight.

Antioxidants, the antioxidants of the present invention are BHT, BHA, and vitamin E acetate, and vitamin E acetate is preferred in the present invention. The hair care compositions of the present invention comprise from 0.05% to 5.0% by weight of the composition. Further optimized to 0.2% to 1.5%.

Chelating Agents, non-limiting examples of the chelating agents of the present invention are: ethylenediaminetetraacetic acid, disodium edetate, tetrasodium ethylenediaminetetraacetate, preferably disodium edetate. The chelating agent in the present invention comprises from 0.01% to 0.50% by weight of the composition, further optimized to be from 0.05% to 0.3%.

Preservatives, the preservatives of the present invention are methylparaben, propylparaben, phenoxyethanol and octanoyl hydroxamic acid. Among them, octanoyl hydroxamic acid is an organic acid which is in the form of a white powder. The molecular structure contains a hydroxyl group and an octyl group. It is called an amphiphilic surfactant, and the octanoyl group has a suitable carbon chain length. It can promote the explanation of microbial cell membrane structure, has good inhibitory effect on mold, and is milder than paraben, carson and formaldehyde release preservative. In addition to the antiseptic effect, the octanoyl hydroxamic acid has a mild moisturizing effect on the scalp and a synergistic moisturizing effect in the present invention. The pH of the octanoyl hydroxamic acid is in the range of 3-7, the molecular formula C ₈ H ₁₇ NO ₂ , and the chemical structural formula is as in the structural formula I. The octanoyl hydroxamic acid of the invention is produced by Kunshan Shuangyou Daily Chemical Co., Ltd.

Octanoyl hydroxamic acid structural formula I.

The preservatives of the present invention are phenoxyethanol and octanoyl hydroxamic acid, wherein the phenoxyethanol comprises from 0.05% to 0.8% by weight of the composition of the invention, preferably from 0.05% to 0.6%. The octanoyl hydroxamic acid comprises from 0.05% to 0.5% by weight of the composition of the invention, optimized from 0.05% to 0.3%. The antiseptic system of the present invention, by formulating phenoxyethanol and octanoyl hydroxamic acid, can reduce the irritation of the cationic surfactant through challenging experiments, so that the composition of the present invention is gentler to the scalp and hair and has a synergistic nourishing effect.

The hair care composition of the present invention further contains an appropriate amount of flavor, pigment, and the like. The selection of the essence and the pigment meets the requirements of the hygienic standard of the cosmetics, and the safe raw materials are selected.

Preparation. The compositions of the present invention can be prepared by any of the known or otherwise effective techniques suitable for providing hair care compositions, and methods of preparing the compositions of the present invention include conventional formulation and mixing techniques.

Instructions. The compositions of the present invention are used in a conventional manner for cleansing and conditioning hair, and include the following steps:

(A) Wash the hair with a proper amount of shampoo;

(B) applying to the hair an effective amount of the hair care composition of any of the preceding claims, wrapped with a hot towel for 5-15 minutes, further optimized to 5-10 minutes, the effective dose typically being in the range of 1 Grams to 30 grams, preferably 2 to 10 grams;

(C) or rinsing the composition on the hair with water.

These steps can be repeated as many times as needed to achieve the desired therapeutic effect.

Example

The following are non-limiting examples of the compositions of the present invention. The examples are given for the purpose of illustration only, and are not to be construed as limiting the scope of the invention. In these examples, all concentrations are by weight unless otherwise stated.

Preparation Example I-X

Suitable methods of preparing the ointment compositions of Examples I-X are as follows:

Add appropriate amount of water to the aqueous phase reaction tank, add guar hydroxypropyltrimethylammonium chloride dispersion, add disodium edetate, alkyl quaternary ammonium salt including behenyltrimethyl chloride Ammonium or dioctadecyldimethylammonium chloride, part of dipropylene glycol, etc., is heated to 80 ° C, and carbon 16/18 alcohol, carbon 22 alcohol, vitamin E acetate is added to another oil phase reaction tank, and the temperature is raised to At 80 ° C and mix well, the oil phase is added to the water phase to homogenize and then cooled. Add the moisturizing complex active agent to the temperature of 45 ° C and homogenize for 5 minutes. Continue to cool down 40 ° C to add dipropylene glycol, preservative, pigment Stirring after the fragrance or the like is continued to ensure a homogeneous mixture.

Example I-V

Example VI-X

The preferred embodiment of the invention is:

Component	weight(%)
Dioctadecyldimethylammonium chloride	2.5
Polyquaternium-10	0.45
Hydroxyethyl cellulose	0.60
Carbon 16/18 alcohol	3.5

Carbon 22 alcohol	3.5
Moisturizing compound active agent *	12.0
Phenoxyethanol	0.45
Octanoyl hydroxamic acid	0.22
Dipropylene glycol	5.0
Vitamin E acetate	1.1
Disodium edetate	0.25
Fragrance, pigment	Moderate amount
Deionized water	Add to 100%

In the examples I-X, the components and content (weight ratio) of the moisturizing composite active agent are: 26% hexanediol, 15% sugar mixture (the sugar mixture is composed of monosaccharide, oligosaccharide) , polysaccharide composition, and monosaccharide: oligosaccharide: polysaccharide is mixed in a ratio of weight ratio of 5:2:1; monosaccharide is composed of fructose and glucose, and fructose: glucose is mixed in a ratio of 1:1 by weight; The sugar is composed of sucrose, cyclodextrin, and sucrose: cyclodextrin is mixed at a ratio of 1:0.5 by weight; the polysaccharide is sodium hyaluronate), and contains 15% of water-soluble silicone oil (the water-soluble silicone oil is dimer B) Glycol-15-methyl ether polydimethylsiloxane), containing 10% amino acid mixture (the amino acid mixture is alanine: serine: glycine: glutamic acid: cysteine in a weight ratio of 1:1 : 1: 0.2: 0.1 ratio of mixing), containing 2% sodium pyrrolidone carboxylate (PCA sodium), containing 2% hydroxyethyl urea and the balance of water.

Verification of hair moisturizing effect

Hair moisturizing in vitro test:

Preparation of standard hair bundles (naturally intact hair bundles) and damaged hair bundles

The hair bundle, which is naturally untreated and untreated, is also called a standard hair bundle and is passed through a commercially available standard hair bundle and weighs 18-20 grams.

The standard hair tresses are treated with a permanent perm solution and the damaged (moderately damaged) tresses are obtained for later use.

Take six bundles of hair, three of which are standard hair bundles, the other three bundles are treated moderately damaged hair bundles, and the six bundles of hair bundles are put together and cleaned with shampoo and gently wiped with a towel until dripping At this time, the hair bundle is in a semi-dry or wet state, and then the six hair bundles are respectively treated with the hair growth and hair-preparation samples prepared in the comparative example 1, the comparison 2, the embodiment II and the embodiment VIII, respectively. The bundle was treated with 1.5 g hair care hair samples, rinsed with water, air dried, and set aside.

Six bundles of hair after natural airing were combed with a comb, and then six bundles of hair were disorderly sequenced and randomly assigned to six trained evaluators, and then the sensory effects of the hair bundle were evaluated separately: moisturizing, gloss, combing Sex, flexibility, volume, each parameter scored 0-5 points, 5 is the highest score, the highest score is set to A, and so on until the lowest score D, the evaluation results are shown in Table 1 and Table 2,

Table 1

Table 2

From the above ex vivo experiments, the scores of Example II of the present invention and Example VIII of the present invention were higher than those of Comparative 1 and Comparative 2, wherein the score of Example VIII of the present invention was the highest.

Scalp comfort and hair moisturizing human test

Test the moisturization of the scalp after using the product

Volunteer choice. To test the moisturizing effect of hair after shampooing, one important thing is to choose the right volunteer. The selection of volunteer hair types (dry, neutral, oily) is very important. The occurrence of dry hair often comes from three situations, one is physiological, the other is pathological, and the third is environmental or human factors. The hair loses the necessary oilyness, it will appear boring, the real hereditary dry hair is relatively rare, only 5% of the life is dry hair, this dry hair is usually rough and stiff, often entangled in a group due to curling, Glossy. Most people's dry hair belongs to the third type, which is caused by excessive sun exposure, dry air blowing or improper use of shampoo. Therefore, many people mistakenly take shampoo reduction after they have found images. The number of times, it is expected that the naturally secreted head oil will gather to moisturize the hair, resulting in a large amount of dandruff until the fat glands of the hair follicles are blocked, resulting in a drier hair. Therefore, when the volunteers of the present invention select a volunteer in the third case, the test will produce a market value with better reference value.

Clinical test methods for scalp comfort, hair moisturization and conditioning:

The scalp comfort, hair moisturization and conditioning evaluation method is: the preparation examples I-X and the comparative 1 embodiment and the comparative 2 embodiment are respectively sent to 60 dry hair volunteers who meet the third situation described above. . Volunteers use the shampoos that they used to use before using the samples of the present invention, and then use the samples of the examples of the present invention (washing once every one to two days, using the sample of the invention once after each shampoo), using After one week, the tester scored according to his or her own feelings (requires the hair to be scored in a natural dry state). The score is based on a 7-point scale. The final statistical score, the higher the score, the better the effect; the scalp comfort score method: 1 point (the scalp is better than before Itchy,) represents the worst, 7 points (sweet scalp, basically no discomfort, scalp is not itchy, dandruff is also reduced) represents the best; hair moisturizing score method: 1 point (hair moisturization did not improve, Hair moisturizing feeling is similar to before), 7 points (hair moisturizing is obviously improved, hair is elastic, hair is textured, hair tail is gone, hair is more shiny); hair conditioning is scored: 1 point (hair There is no improvement in conditioning, hair combing is not even as good as before.), 7 points (hair conditioning is improved after wet washing and drying, feeling hair is smooth and elastic) The results are shown in Table 3 valence.

Table 3 scalp comfort and hair moisturizing sexy evaluation statistics

From the above sensory evaluation, it can be concluded that the inventive examples I to X have significant advantages in comparison with the comparative 1 embodiment and the comparative 2 embodiment in terms of the scalp comfort sexy score and the hair moisturizing sexy score. An improvement in scalp comfort indicates an increase in the moisturability of the composition of the present invention on the scalp. Theoretically, Examples I to X of the present invention have a certain effect on the barrier function of the scalp. In addition, the hair conditioning scores of the examples of the present invention were not significantly different from the samples of Comparative 1 and Comparative 2.

Claims (7)

1. A hair care hair care composition containing a high-efficiency hair moisturizing compound, in addition to preservatives, flavors, chelating agents, antioxidants and water, comprises:

   (A) a cationic polymer in an amount of from 0.05% to 0.5% by weight of the composition;

   (B) a cationic surfactant in an amount of from 0.5% to 3% by weight of the composition;

   (C) a fatty alcohol thickener in an amount of from 0.5% to 10.0% by weight of the composition;

   (D) a hydroxyethylcellulose nonionic cellulosic polymer thickener in an amount of 0.05% to 1% by weight of the composition;

   Wherein the fatty alcohol thickener is a mixture of cetearyl alcohol and behenyl alcohol, and cetearyl alcohol: behenyl alcohol is mixed in a ratio of 1:1 by weight;

   (E) a hair moisturizing complex active agent in an amount of from 1.0% to 20% by weight of the composition, the hair moisturizing complex active agent being composed of the following components:

   Hexanediol, which accounts for 10-28% by weight of the composite active agent,

   a mixture of sugars of 10-20% by weight of the composite active agent, the sugar mixture is composed of monosaccharides, oligosaccharides and polysaccharides, and the monosaccharide: oligosaccharide: polysaccharide is mixed in a ratio of 5:2:1 by weight. The monosaccharide is fructose and glucose, and the fructose: glucose is mixed in a ratio of 1:1 by weight; the oligosaccharide is sucrose and cyclodextrin, and the sucrose: cyclodextrin is mixed at a weight ratio of 1:0.5; Sodium hyaluronate, having a molecular weight of 400,000 Da to 2.2 million Da;

   a water-soluble silicone oil which is 3-20% by weight of the composite active agent, and the water-soluble silicone oil is diethylene glycol-15-methyl ether polydimethylsiloxane;

   a mixture of amino acids 5-10% by weight of the composite active agent, the amino acid mixture is composed of alanine, serine, glycine, glutamic acid, cysteine, and alanine: serine: glycine: glutamic acid: half Cystine is mixed at a weight ratio of 1:1:1:0.2:0.1;

   Sodium pyrrolidone carboxylate, 1-5% by weight of the composite active agent;

   Hydroxyethyl urea in an amount of 0.5-3% by weight of the composite active agent;

   The balance is water.
2. A hair care hair care composition according to claim 1 comprising propylene glycol in an amount of 5% by weight of the composition.
3. The hair care hair care composition according to claim 1, wherein the cationic polymer is selected from at least one of a cationic cellulose polymer and a cationic guar polymer.
4. A hair care hair care composition according to claim 1 wherein said cationic surfactant is selected from at least one of behenyltrimethylammonium chloride and dioctadecyldimethylamine chloride. .
5. The hair care hair care composition according to claim 1, wherein the hydroxyethyl cellulose has a viscosity of from 85,000 to 100,000 mPa.s.
6. The hair care hair care composition according to claim 1, wherein the glycine is trimethylglycine.
7. The hair care hair care composition according to claim 1, wherein the sodium hyaluronate has a molecular weight of from 1,000,000 Da to 1.8 million Da.