WO2017163980A1 - 化粧品 - Google Patents
化粧品 Download PDFInfo
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- WO2017163980A1 WO2017163980A1 PCT/JP2017/009975 JP2017009975W WO2017163980A1 WO 2017163980 A1 WO2017163980 A1 WO 2017163980A1 JP 2017009975 W JP2017009975 W JP 2017009975W WO 2017163980 A1 WO2017163980 A1 WO 2017163980A1
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- preparation
- filling
- inner layer
- gel
- formulation
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/02—Cosmetics or similar toiletry preparations characterised by special physical form
- A61K8/04—Dispersions; Emulsions
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/02—Cosmetics or similar toiletry preparations characterised by special physical form
- A61K8/04—Dispersions; Emulsions
- A61K8/042—Gels
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/02—Cosmetics or similar toiletry preparations characterised by special physical form
- A61K8/03—Liquid compositions with two or more distinct layers
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/19—Cosmetics or similar toiletry preparations characterised by the composition containing inorganic ingredients
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/33—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing oxygen
- A61K8/34—Alcohols
- A61K8/345—Alcohols containing more than one hydroxy group
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/33—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing oxygen
- A61K8/37—Esters of carboxylic acids
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/72—Cosmetics or similar toiletry preparations characterised by the composition containing organic macromolecular compounds
- A61K8/81—Cosmetics or similar toiletry preparations characterised by the composition containing organic macromolecular compounds obtained by reactions involving only carbon-to-carbon unsaturated bonds
- A61K8/8141—Compositions of homopolymers or copolymers of compounds having one or more unsaturated aliphatic radicals, each having only one carbon-to-carbon double bond, and at least one being terminated by only one carboxyl radical, or of salts, anhydrides, esters, amides, imides or nitriles thereof; Compositions of derivatives of such polymers
- A61K8/8152—Homopolymers or copolymers of esters, e.g. (meth)acrylic acid esters; Compositions of derivatives of such polymers
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q1/00—Make-up preparations; Body powders; Preparations for removing make-up
- A61Q1/14—Preparations for removing make-up
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q19/00—Preparations for care of the skin
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2800/00—Properties of cosmetic compositions or active ingredients thereof or formulation aids used therein and process related aspects
- A61K2800/20—Chemical, physico-chemical or functional or structural properties of the composition as a whole
- A61K2800/26—Optical properties
- A61K2800/262—Transparent; Translucent
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2800/00—Properties of cosmetic compositions or active ingredients thereof or formulation aids used therein and process related aspects
- A61K2800/40—Chemical, physico-chemical or functional or structural properties of particular ingredients
- A61K2800/41—Particular ingredients further characterized by their size
- A61K2800/412—Microsized, i.e. having sizes between 0.1 and 100 microns
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2800/00—Properties of cosmetic compositions or active ingredients thereof or formulation aids used therein and process related aspects
- A61K2800/80—Process related aspects concerning the preparation of the cosmetic composition or the storage or application thereof
- A61K2800/87—Application Devices; Containers; Packaging
Definitions
- the present invention relates to a cosmetic product in which a gel-like, cream-like or semi-solid preparation is filled in a container, and the preparation contains a colloid and the preparation is stably encapsulated in a predetermined shape.
- the applicant first uses a preparation having a different composition in the inner layer and the outer layer to suppress a mixture over time at the interface between the inner layer preparation and the outer layer preparation, and to provide a cosmetic that can maintain stability. Proposed (see Patent Document 1).
- a specific viscosity gradient can be obtained by blending a solidifying agent in the outer layer composition and the inner layer composition composed of the same base.
- a multilayer transparent gel composition that has been adjusted to have has been proposed (see Patent Document 2).
- Patent Document 1 when the technique of Patent Document 1 is used, stable and highly reproducible filling is possible even under room temperature conditions, and the inner layer can be maintained in a desired shape even after filling.
- the inner layer preparation may gradually exude to the outer layer over time. Therefore, even if the dosage form is the same, there is room for further improvement from the viewpoint of maintaining the shape of the inner layer preparation for a long period of time and suppressing mixing of the preparations at the interface.
- the present invention has been made in view of the circumstances as described above, and in cases other than a preparation in which the inner layer is an emulsified composition and the outer layer is an aqueous gel (for example, when the gels are combined),
- a novel cosmetic product that has both the functionality of the preparation and the preparation of the outer layer, can stably maintain a multi-layer state in which the inner layer preparation is included in the outer layer preparation for a longer period of time, and is excellent in aesthetics. It is an object.
- the present inventor has formulated a colloid as a component of the preparation, so that the case where the inner layer is an emulsion composition and the outer layer is an aqueous gel (for example, the same) Even in the case of preparations having dosage forms), it is possible to stably maintain a multi-layer state in which the inner layer preparation is encapsulated in the outer layer preparation for a longer period of time, and a cosmetic product with excellent aesthetics is provided. As a result, the present invention has been completed.
- this invention includes the following aspects.
- a cosmetic comprising a transparent or translucent container, a transparent or translucent preparation A filled in the container, and a preparation B embedded in the preparation A, At least one of the formulations A and B comprises a colloid, Cosmetics.
- the metal colloid is a metal colloid selected from the group consisting of platinum, gold, silver, palladium, rhodium, ruthenium, iridium and combinations thereof, and alloys made by mixing these metals.
- the cosmetics described. (Item 9) The cosmetic according to any one of items 1 to 8, wherein the maximum load indicating the viscosity of the preparation measured under the following conditions of the preparation A and the preparation B is 0.2 N to 2.0 N: Measured with SUN RHEO METER (COMPAC100-II) manufactured by San Kagaku Co., Ltd., and the maximum load applied to the cross-sectional area of the rod-shaped probe when a rod-shaped probe having a diameter of 20 mm is penetrated by 25 mm at a speed of 60 mm / min is measured. . (Item 10) 10. The cosmetic according to any one of items 1 to 9, wherein the ratio of the preparation B to the total preparation is 10 to 60% by weight.
- the formulation B has a spherical shape, a spherical shape, an oval shape, an oblate spherical shape, an elliptical cross section, a true spherical shape with protrusions on the surface, a spherical shape with protrusions on the surface, an oval shape with protrusions on the surface, and a protrusion on the surface.
- Item 11 The cosmetic according to any one of Items 1 to 10, wherein the cosmetic is a shape selected from the group consisting of an oblate shape and an elliptical cross-section with a protrusion on the surface.
- each of the inner layer formulation and the outer layer formulation can be used in cases other than the formulation in which the inner layer is an emulsified composition formulation and the outer layer is an aqueous gel formulation (for example, when the dosage form is the same).
- a novel cosmetic product that can stably maintain a multi-layer state in which the inner layer preparation is included in the outer layer preparation for a longer period of time and has an excellent aesthetic appearance is provided.
- FIG. 1 is a schematic explanatory drawing which shows the various forms of the cosmetics which concern on one Embodiment of this invention.
- the inner layer gel (a) immediately after filling, (b) 6 hours after filling, (c) 24 hours after filling, (d ) A photographic image showing the state of the preparation 48 hours after filling.
- the inner layer gel (a) immediately after filling, (b) 6 hours after filling, (c) 24 hours after filling, (d ) A photographic image showing the state of the preparation 48 hours after filling.
- the outer layer gel of the formulation 1 was filled in the inner layer gel of the formulation 6 in the Examples, (a) immediately after the filling of the inner layer gel, (b) 6 hours after the filling, (c) 24 hours after the filling, (d ) A photographic image showing the state of the preparation 48 hours after filling.
- the same dosage form or “the same dosage form” means that a plurality of preparations are prepared using the same kind of base material.
- the substrate include, but are not limited to, a water-soluble substrate, an oily substrate, an emulsion substrate, a gel substrate (for example, an aqueous gel or an oily gel), and the like.
- “colloid” refers to a liquid, a semi-solid or a fine particle of a substance dispersed in a solid, or a state in which the fine particle (hereinafter also referred to as “colloid particle”) is dispersed.
- a state in which colloidal particles are dispersed in a liquid is called a “colloid dispersion” or “colloid solution”.
- the fine particles are metal fine particles, and such a colloid is referred to as a “metal colloid”.
- metal fine particles are nano-sized (nanoparticles) they are also called “metal nanocolloids”.
- the term “spherical” is not limited to a true sphere, but a slightly distorted sphere (for example, an egg), an oblate sphere (for example, an oval cross section), or a slight protrusion on the surface. Some spherical shapes are included.
- the “hemisphere” is not limited to a hemisphere, but includes a hemisphere having a slight distortion, a hemisphere having a slight protrusion on the surface, and the like.
- aqueous component refers to a component that can be dissolved and / or diluted with water.
- oil component refers to a substance that is liquid or solid at room temperature, insoluble in water, viscous, has a specific gravity smaller than water, and burns.
- emulsification refers to a liquid, semi-solid, or uniform mixture of solids that do not dissolve together, such as aqueous and oily components.
- ⁇ Cosmetics> 1 (a) to 1 (d) are schematic explanatory views showing various forms of a cosmetic 1 according to an embodiment of the present invention. As shown in FIGS. 1 (a) to 1 (d), the cosmetic 1 includes a transparent or translucent container 2, a transparent or translucent preparation A filled in the container 2, and a preparation A embedded in the preparation A. Formulation B contained.
- the preparation B has a protruding surface.
- the preparation B may be spherical, and in this case, the preparation B can be embedded in a floating state in the preparation A.
- the lower part of the formulation B may be contacting the bottom face of the container 2, In that case, the upper part of the formulation B becomes a substantially hemispherical shape.
- the preparation B contacts the bottom surface of the container 2 directly or through a thin layer of the preparation A.
- FIG.1 (c) in the state which the formulation A wraps the formulation B, the state where the upper center vicinity of the formulation A is rising may be sufficient.
- the formulation B may be elliptical shape long in the vertical direction.
- (1. Container) As the container 2, the preparation A and the preparation B filled therein can be seen from the outside, and a container used for cosmetics such as ordinary creams and gels is preferable.
- the shape, material, etc. are not particularly limited.
- the shape of the container 2 can be appropriately changed according to the filling amounts of the preparation A and the preparation B, the desired appearance, and the like.
- examples of the dosage form of the preparation A and the preparation B include, but are not limited to, gel, cream, and semisolid.
- the color tone of the preparation is not particularly limited.
- the formulation may be cloudy, white, transparent, colored gel, or an emulsified composition.
- the outer layer preparation A is preferably colored or non-colored transparent or translucent, especially when the preparation is an aqueous gel.
- Formulation A and Formulation B are the same dosage form.
- a combination of the preparation A and the preparation B for example, a combination of two preparations of “aqueous gel” that replenishes the skin and the like with water and a moisturizing ingredient, and “oily gel” that replenishes the skin and the like with an oily ingredient and a moisturizing ingredient.
- a combination of two types of preparations a combination of an “aqueous gel” and an “oil-based gel”, an “aqueous gel cleaner” containing an aqueous cleaning component and an “oil-based gel cleaning agent” containing an oil-based cleaning component
- a combination of two types of formulations of “cream” that replenishes the skin with an oily component and a moisturizing component but are not limited thereto.
- the preparation B is preferably transparent or translucent.
- At least one of the preparation A and the preparation B contains a colloid.
- a colloid particle for example, solid (for example, metal, iron hydroxide (III), etc.) insoluble in a dispersion medium is mentioned.
- the colloid is a metal colloid.
- the metal colloid include, but are not limited to, platinum, gold, silver, palladium, rhodium, ruthenium, iridium and combinations thereof, and alloys formed by mixing these metals. In particular, platinum, gold, silver, and combinations thereof are more preferable.
- colloidal particles of metals such as platinum, gold, and silver are negatively charged.
- it is blended into the dosage form of formulation B and formulation B as necessary. It is understood that the relationship between the properties of the cosmetic ingredients and the like and the charge (positive charge or negative charge) carried by the colloidal particles can be considered.
- a commercially available product may be used, or a product manufactured by a generally known manufacturing method may be used.
- gold colloid for example, as a gold colloid, Sigma-Aldrich Co., which is commercially available in a dispersion state.
- Gold colloid manufactured by Ltd. nano gold dispersion manufactured by Renaissance Energy Research Co., Ltd., gold colloid PD-S manufactured by Dainippon Chemical Industry Co., Ltd., and gold colloid solution manufactured by Jozen Co., Ltd. can be used as they are.
- the silver colloid include Sigma-Aldrich Co., which is commercially available in a dispersion state. It is possible to use a silver suspension manufactured by Ltd. Silver Suspension and a nano silver dispersion manufactured by Renaissance Energy Research Co., Ltd. as they are.
- platinum colloid As the platinum colloid, a commercially available nano platinum dispersion liquid manufactured by Renaissance Energy Research Co., Ltd. prepared in a dispersion state can be used as it is.
- Formulation A when Formulation A has embedded Formulation B, (1) Formulation B includes a colloid, and Formulation A does not include a colloid, but (2) Formulation A includes a colloid.
- the preparation B may not contain a colloid.
- the color tone of the inner layer formulation B can be made deeper than the color tone of the outer layer formulation A, and the contrast of the outer layer and inner layer color tone can be visually recognized from the outside of the container 2, From the viewpoint of the aesthetics of the cosmetic 1, it is more preferable.
- the preparation A and the preparation B may contain a colloid, and the colloid concentration contained in the preparation A may be different from the colloid concentration contained in the preparation B. In this case, when the concentration of the colloidal dispersion liquid blended in the inner layer preparation B is increased, when the cosmetic 1 is observed from the outside of the container 2, the color tone of the inner layer can be raised with respect to the outer layer.
- the color tone of the outer layer and the inner layer can be changed, and the aesthetics of the cosmetic 1 can be enhanced.
- Formulation B contains a colloid.
- the blending amount of the colloid in the preparation B embedded in the preparation A can be appropriately adjusted according to the combination of the preparation A and the preparation B, the desired color tone of the preparation B, and the like.
- the blending amount of the colloidal dispersion with respect to the total amount of the preparation B is 0.001 to 50.00% by weight, preferably 0.005 to 45.00% by weight, and more preferably 0.01 to 43.3%. 00% by weight.
- the colloid is a metal colloid
- the compounding amount of the metal colloid dispersion with respect to the total amount of the preparation B is 0.5 to 50.00% by weight, preferably 1.0 to 45.00%. %, More preferably 2.0 to 43.00% by weight.
- the average particle size of the colloidal particles is not particularly limited, and is, for example, 1 nm to 10 ⁇ m, preferably 1 nm to 7 ⁇ m, more preferably 1 nm to 5 ⁇ m. Further, even when the colloid is a metal colloid, the average particle diameter of the metal colloid is not particularly limited, but considering the stability of the metal colloid in the preparation B, it is preferable to use a metal colloid of 1 nm to 100 nm. More preferably, a metal colloid of ⁇ 100 nm is used.
- the average particle diameter of the colloidal particles is measured according to a generally known method such as a dynamic light scattering method or a laser diffraction method.
- a dynamic light scattering method for example, in the case of nano-sized colloidal particles such as metal nanocolloids, it is preferable to measure the average particle diameter using a dynamic light scattering method.
- the dispersibility of colloidal particles can be evaluated by measuring the zeta potential together with the average particle diameter.
- the aesthetics of the cosmetic 1 is adjusted by adjusting the type, blending amount, average particle diameter of the metal colloid particles, and the like of the metal colloid dispersion to be blended with the preparation A and / or the preparation B.
- Can do For example, when a highly transparent aqueous gel containing no colloid is used as the outer layer preparation A, and a metal colloid dispersion is blended with the inner layer preparation B, the color of the metal colloid contained in the inner layer preparation B is developed.
- the cosmetic 1 having an excellent aesthetic appearance can be obtained by contrast of the color tone between the outer layer and the inner layer.
- the metal colloid dispersion liquid is blended in both the preparation A and the preparation B, for example, by increasing the concentration of the metal colloid dispersion liquid blended in the inner layer preparation B, the color tone of the inner layer with respect to the outer layer is increased. It can be raised and the aesthetics of the cosmetic 1 can be enhanced.
- the color tone of the outer layer and the inner layer can be changed, and the aesthetics of the cosmetic 1 can be enhanced.
- the preparation A and / or the preparation B when a highly transparent colored aqueous gel to which an arbitrary colorant is added is used as the preparation A and / or the preparation B, an addition to the color tone by the metal colloid contained in the preparation A and / or the preparation B is used.
- the aesthetics of the cosmetic 1 can also be enhanced by the effect or the synergistic effect.
- the viscosity of the preparation A and the preparation B is not particularly limited, but if the viscosity is too low, the preparation B moves to the outer preparation A or is mixed with the preparation A due to impact or the like, and the shape after filling is stabilized. May not be able to keep up. If the viscosity is too high, it may be difficult to fill the preparation or the comfort of the product may be impaired.
- the formulation A of the outer layer and the formulation B of the inner layer do not maintain the two-layer state in which the formulation B is included in the formulation A by providing a gradient in viscosity. . That is, in this embodiment, it is not necessary to intentionally provide a difference in viscosity between the preparation A and the preparation B.
- the preparation A and the preparation B are non-fluid and not too hard. Furthermore, considering the ease of use of the preparation, the ease of filling in the production process, and the necessity of filling the inner layer preparation B in a substantially spherical shape, the outer layer preparation A and the inner layer preparation B have the same degree. It is desirable for the formulation to have a viscosity of
- the viscosity of the preparation can be expressed by the maximum load according to the following measurement method.
- the maximum load of the preparation is preferably 0.2N to 2.0N, more preferably 0.3N to 1.0N. If the maximum load is less than 0.2N, it may be difficult to maintain a stable shape of the preparation as described above, and if it is more than 2.0N, filling the preparation may be difficult and the comfort of the product may be impaired. .
- the maximum load of the preparation is measured by SUN RHEO METER (COMPAC100-II) purchased from Sun Scientific Co., Ltd., and it takes about 25 mm of a rod-shaped probe having a diameter of 20 mm at a speed of 60 mm / min to be applied per sectional area of the rod-shaped probe Measure the maximum load.
- the maximum load measurement is performed at room temperature, eg, 20 ° C., 25 ° C., or 30 ° C., typically 25 ° C.
- each preparation can be adjusted depending on the use and formulation of each preparation, but the specific gravity of preparation A is preferably 0.8 to 1.3, more preferably 0.9 to 1.2.
- the specific gravity of the preparation B is preferably 0.7 to 1.2, more preferably 0.8 to 1.1.
- the ratio of the preparation A to the preparation B in the cosmetic 1 can be adjusted to an arbitrary value depending on the use and prescription of each preparation, but considering the aesthetics of the cosmetic 1, the ratio of the preparation B with respect to the total amount of the preparation is 10-60. % By weight is preferred, and more preferably 20 to 40% by weight.
- the proportion of the preparation B is less than 10% by weight of the total amount of the preparation, the function of the preparation B may not be exhibited.
- the ratio exceeds 60% by weight, the function of the preparation A may not be exhibited. Appearance may be impaired.
- the preparation A and the preparation B can be blended with any water-soluble substance, any substance that can be dispersed in a gel, or a solid substance.
- ingredients that can be blended in the preparation include oils and fats, waxes, hydrocarbons, silicones, fatty acids, alcohols, esters, surfactants, thickeners, powders, and other cosmetic bases, as well as pharmaceuticals And active ingredients of quasi-drugs, pH adjusters, preservatives, dyes, fragrances, antioxidants, and naturally derived extracts.
- the preparation A and the preparation B may contain an oil component, and examples of such an oil component include, but are not limited to, a substance selected from the group consisting of: : Avocado oil, almond oil, olive oil, camellia oil, sesame oil, rice bran oil, safflower oil, soybean oil, corn oil, rapeseed oil, kyounin oil, persic oil, peach seed oil, castor oil, sunflower oil, grape seed oil, cottonseed oil, coconut oil , Wheat germ oil, rice germ oil, evening primrose oil, hybrid sunflower oil, macadamia nut oil, meadow foam oil, hazelnut oil, palm kernel oil, palm oil, palm oil, cocoa butter, shea butter, wax, mink oil, Oils and fats such as turtle oil, egg yolk oil, beef tallow, milk fat, pork fat, field oil; or waxes such as jojoba oil, carnauba wax, candela wax, rice bran, orange raffi oil, beeswa
- isopropyl myristate isopropyl palmitate, butyl stearate, ethyl oleate, cetyl palmitate, myristyl myristate, octyldodecyl myristate, octyldodecyl oleate, cholesteryl stearate, cholesteryl hydroxystearate, tricaprin , Trimyristin, glyceryl tri-2-ethylhexanoate (trioctanoin), isopropyl isostearate, isopropyl isostearate, ethyl isostearate, cetyl ethylhexanoate, stearyl ethylhexanoate, glyceryl triethylhexanoate, glyceryl triethylhexanoate, triethyl Trimethylolpropane hexano
- the preparation A and the preparation B may contain a moisturizing component.
- a moisturizing component include substances selected from the group consisting of the following: Not limited to: Glycerin, 1,3-butylene glycol, propylene glycol, 3-methyl-1,3-butanediol, 1,3-propanediol, 2-methyl-1,3-propanediol, trimethylolpropane, pentaerythritol, hexylene Glycol, diglycerin, polyglycerin, diethylene glycol, polyethylene glycol, dipropylene glycol, polypropylene glycol, ethylene glycol, diethylene glycol monoethyl ether (ethoxydiglycol), ethylene glycol monoethyl ether, ethylene glycol monobutyl ether, diethylene glycol dibutyl ether, sorbitol, Xylitol, erythritol, mannitol, malti
- various cosmetic ingredients that can be generally blended into cosmetics can be added to the preparation A and the preparation B in addition to the above-described components or in place of the above-described components.
- a cosmetic component which is a polymer compound
- the formulation B contains a colloid, thereby preventing the cosmetic component from dispersing from the inner layer to the outer layer at the interface between the outer layer and the inner layer.
- the cosmetic ingredient can be retained in the inner layer for a long period of time. Therefore, it is possible to use a plurality of formulations more efficiently with one product.
- the pigment to be added is not particularly limited as long as it is a pigment that is uniformly dispersed in the preparation.
- Representative pigments include Red No. 2, Red No. 3, Red No. 102, Red No. 106, Yellow No. 4, Yellow No. 5, Green No. 3, Blue No. 1, Blue No. 2, Red No. 201, Red No. 213.
- Red 214 Red 227, red 231, red 232, orange color 205, orange color 207, yellow 203, green 201, green 204, green 205, blue 202, blue 203 , Blue 205, Blue 205, Brown 201, Red 401, Red 502, Red 503, Red 504, Red 506, Orange 402, Yellow 402, Yellow 406, Yellow 407
- synthetic colorants such as green 401, green 402, purple 401, black 401, gardenia pigment, cyanocobalamin, purple root extract, azulene and its derivatives, chlorophyll and Derivatives, including but dyes and coloring ingredients such as cochineal pigment without limitation. These dyes can be added alone or in any combination.
- the cosmetic 1 according to this embodiment since at least one of the preparation A and the preparation B contains a colloid or contains different types of colloids, mixing at the interface between the preparation A and the preparation B is suppressed, and the preparation A It is possible to stably maintain a multilayer state in which the preparation B is encapsulated in a longer period of time. Therefore, the cosmetic 1 according to the present embodiment can maintain a multi-layered state not only in an unused state (before opening) but also after the opening of the cosmetic 1, even if the amount of the preparation is reduced by use. Therefore, the cosmetic 1 according to the present embodiment is not only excellent in the shape retention of the formulation, but also can be stably maintained for a long period of time in terms of aesthetics, and the feeling of use for the user. An effect such as an improvement in (the actual feeling that the target cosmetic ingredient is applied to the skin) is also expected.
- the cosmetic of the present invention can obtain the effects of the present invention even when two or more types of formulation are used.
- Can do That is, for example, a preparation having the same dosage form as the preparations A and B can be encapsulated in the preparation B to form a cosmetic having a structure of three or more layers.
- the inner layer preparation B may be embedded in a plurality of locations inside the outer layer preparation A (the inner layer preparation B may have a so-called polka dot appearance).
- the cosmetic 1 according to this embodiment can be manufactured by first filling the container 2 with the outer layer preparation A and then filling the inner part of the preparation A with the inner layer preparation B.
- the filling method of the preparation A and the preparation B is not particularly limited, and each preparation can be filled as it is or with rotation, using a filling machine or a syringe used in a normal cosmetic manufacturing process.
- the preparation B can be produced by inserting a nozzle into the preparation A previously filled and filling it.
- a protrusion may be formed on the upper surface of the preparation B that forms the projecting curved surface.
- the cosmetic 1 having the functionality of two types of preparations A and B can be provided in one product by filling two kinds of preparations having different functions in two stages.
- the preparation A such as a highly transparent aqueous gel is used for the outer layer
- the preparation B containing the colloid is filled in the preparation A, thereby allowing the container 2 and the preparation A to pass through.
- the preparation B having a color tone and a curved surface exhibited by the colloid can be visually recognized from the outside, and therefore, a novel cosmetic product excellent in aesthetic appearance can be provided.
- the preparation method of the preparation A and the preparation B is not particularly limited, and can be generally performed according to a known method.
- the desired cosmetic ingredients and the like are weighed at a predetermined ratio, dissolved while heating with stirring, and then dissolved at an arbitrary ratio using purified water.
- An aqueous gel can be prepared by adding a pH adjuster (eg, potassium hydroxide, sodium hydroxide, etc.) and then cooling to room temperature with stirring.
- a pH adjuster eg, potassium hydroxide, sodium hydroxide, etc.
- the method for adding the colloid in the preparation A and / or the preparation B is not particularly limited.
- the preparation is an aqueous gel
- the colloid is added together when the cosmetic ingredients are dissolved by heating with stirring.
- the colloid may be added under heating conditions after adding the pH adjusting agent.
- the ratio of the filling amount of the preparation A that is initially filled in the container 2 and the filling amount of the preparation B that is filled in the second stage is not particularly limited, and the type of the selected preparation, its functionality, and cosmetics 1 is adjusted as appropriate according to the required characteristics.
- the filling amount of the preparation B of the inner layer to be filled in the second stage is desirably within the range of 10% to 60% of the whole preparation, and within the range of 20 to 40%. Although the inside is more desirable, it is not limited to these.
- the filling amount of the preparation B is less than 10% of the whole preparation, the function of the preparation B may not be exhibited.
- it exceeds 60% the function of the preparation A may not be exhibited. May be damaged.
- the container 2 when the container 2 is a shallow container, depending on the filling amount of the preparation to be filled in the second stage and thereafter, the preparation filled in the second and subsequent stages comes into contact with the bottom surface of the container 2 and becomes hemispherical or semi-spherical. Although it is filled in an oblate shape, this does not impair the functionality of the present invention, and does not impair the aesthetics of the invention, and does not affect the implementation of the invention.
- the depth of the container 2 when the depth of the container 2 is sufficiently deep, or depending on the shape of the container 2, it can be filled in a completely spherical shape by adjusting the blending amount of the preparation filled in the second stage. Thereby, it can also be finished in an invention having a slightly different appearance from the former.
- the preparation B to be filled in the second stage needs to be filled in the preparation A filled first, but the place where the preparation B is filled is not particularly limited. Normally, it is desirable to fill the vicinity of the center of the preparation A that has been initially filled. May be. Filling the upper part from the center part makes it difficult for the preparation B to adhere to the bottom of the container 2 and can be filled in a more spherical shape, and the upper part of the preparation A often rises.
- the cosmetic 1 obtained in this manner has the functionality of the outer layer formulation A and the inner layer formulation B, and can stably maintain a multilayer state in which the formulation B is encapsulated in the formulation A for a long period of time. Further, when the preparation A and the preparation B are visually recognized through the container 2, the overall sense of unity due to the combination of the preparation A and the preparation B and the color tone between the preparations due to the preparation A and / or the preparation B containing colloids. Combined with the difference (contrast), it can be set as the cosmetic 1 excellent in aesthetics.
- the outer layer preparation was prepared by the following formulation and manufacturing method.
- A) Methyl paraoxybenzoate 0.15 (% by weight)
- Purified water the remaining amount is added so that the total amount becomes 100 (% by weight) (preparation method)
- the component (A) was dissolved by heating with stirring, and then the component (B) dissolved in 10% using purified water was added.
- the transparent gel was obtained by cooling to room temperature, stirring.
- 100 g was taken in a 100 ml beaker and allowed to stand at room temperature for 24 hours, and then the maximum load and specific gravity were measured. As a result, the maximum load was 0.54 N and the specific gravity was 1.03.
- the maximum load of the gel preparation was measured by SUN RHEO METER (COMPAC100-II) purchased from Sun Scientific Co., Ltd., and the cross-sectional area of the rod-shaped probe when a rod-shaped probe having a diameter of 20 mm was penetrated by 25 mm at a speed of 60 mm / min. The maximum load applied per hit was measured.
- the inner layer preparation was prepared according to the following formulation and manufacturing method.
- A) Methyl paraoxybenzoate 0.15 (% by weight)
- (C) Dye component or colloid shown in Table 1 below)
- the component (A) was dissolved by heating with stirring, and then the component (B) dissolved in 10% using purified water was added.
- dye of a component (C) was added on the addition conditions shown in Table 1, and colored gel was obtained by cooling to room temperature, stirring.
- the platinum silver colloid of prescription 13 is a platinum silver colloid 500 manufactured by JOHZEN Co., Ltd.
- the gold colloid of prescription 14 is a gold colloid PD-S manufactured by Dainippon Chemical Industry Co., Ltd.
- the silver colloid of prescription 15 is Sigma- Aldrich Co. Ltd. Silver suspension was used.
- ⁇ Filling formulation> A transparent resin container having a capacity of 30 g was filled with 20 g of the outer layer gel of Formula 1 from a syringe, and then the tip of the syringe was inserted into the filled outer layer gel and filled with 10 g of the inner layer gel (Formulations 2 to 16).
- ⁇ Evaluation of retention of formulation shape> A product filled with two different gel preparations (two-part filling product) by the above method is stored at room temperature, immediately after filling the inner gel, 6 hours after filling, 24 hours after filling, 48 hours after filling. The state was visually observed. The results are shown in FIGS.
- FIG. 2 shows a two-packed product in which the outer layer gel of formulation 1 is filled with the inner layer gel of formulation 2, (a) immediately after filling, (b) 6 hours after filling, (c) 24 hours after filling, ( d) A photographic image showing the state of the preparation 48 hours after filling.
- the hemispherical inner layer gel was encapsulated in the outer layer gel immediately after the filling of the bright yellow inner layer gel, but after 6 hours of filling, the inner layer gel The boundary with the outer layer gel became unclear, and the hemispherical shape of the inner layer gel could not be confirmed 24 hours after filling.
- FIG. 3 shows a two-packed product in which the outer layer gel of formulation 1 is filled with the inner layer gel of formulation 3, (a) immediately after filling, (b) 6 hours after filling, (c) 24 hours after filling, ( d) A photographic image showing the state of the preparation 48 hours after filling.
- the hemispherical inner layer gel was encapsulated in the outer layer gel immediately after the filling of the bright yellow inner layer gel, but after 6 hours of filling, The boundary with the outer layer gel became unclear, and the hemispherical shape of the inner layer gel could not be confirmed 24 hours after filling.
- FIG. 4 shows a two-packed product in which the outer layer gel of formulation 1 is filled with the inner layer gel of formulation 4, (a) immediately after filling, (b) 6 hours after filling, (c) 24 hours after filling, ( d) A photographic image showing the state of the preparation 48 hours after filling.
- the hemispherical inner layer gel was encapsulated in the outer layer gel immediately after the filling of the bright purple inner layer gel, but after 6 hours of filling, The boundary with the outer layer gel became unclear, and the hemispherical shape of the inner layer gel could not be confirmed 24 hours after filling.
- FIG. 5 shows a two-packed product in which the outer layer gel of the formulation 1 is filled with the inner layer gel of the formulation 5, (a) immediately after the filling of the inner layer gel, (b) 6 hours after the filling, (c) 24 hours after the filling, ( d) A photographic image showing the state of the preparation 48 hours after filling.
- the hemispherical inner layer gel was encapsulated in the outer layer gel immediately after the filling of the bright purple inner layer gel.
- the boundary with the outer layer gel became unclear, and the hemispherical shape of the inner layer gel could not be confirmed 24 hours after filling.
- FIG. 6 shows a two-packed product in which the outer layer gel of formulation 1 is filled with the inner layer gel of formulation 6, (a) immediately after filling, (b) 6 hours after filling, (c) 24 hours after filling, ( d) A photographic image showing the state of the preparation 48 hours after filling.
- the hemispherical inner layer gel was encapsulated in the outer layer gel immediately after the filling of the bright purple inner layer gel.
- the boundary with the outer layer gel became unclear, and the hemispherical shape of the inner layer gel could not be confirmed 24 hours after filling.
- FIG. 7 shows a two-packed product in which the outer layer gel of formulation 1 is filled with the inner layer gel of formulation 7, (a) immediately after filling, (b) 6 hours after filling, (c) 24 hours after filling, ( d) A photographic image showing the state of the preparation 48 hours after filling.
- the hemispherical inner layer gel was encapsulated in the outer layer gel immediately after the filling of the bright purple inner layer gel.
- the boundary with the outer layer gel became unclear, and the hemispherical shape of the inner layer gel could not be confirmed 24 hours after filling.
- FIG. 8 shows a two-packed product in which the outer layer gel of formulation 1 is filled with the inner layer gel of formulation 8, (a) immediately after filling, (b) 6 hours after filling, (c) 24 hours after filling, ( d) A photographic image showing the state of the preparation 48 hours after filling.
- the hemispherical inner layer gel was encapsulated in the outer layer gel immediately after the bright blue inner layer gel was filled, but after 6 hours of filling, the inner layer gel The boundary with the outer layer gel became unclear, and the hemispherical shape of the inner layer gel could not be confirmed 24 hours after filling.
- FIG. 9 shows a two-packed product in which the outer layer gel of formulation 1 is filled with the inner layer gel of formulation 9, (a) immediately after filling, (b) 6 hours after filling, (c) 24 hours after filling, ( d) A photographic image showing the state of the preparation 48 hours after filling.
- the hemispherical inner layer gel was encapsulated in the outer layer gel immediately after the filling of the bright yellow inner layer gel, but after 6 hours of filling, The boundary with the outer layer gel became unclear, and the inner layer gel and the outer layer gel were uniformly mixed 24 hours after filling.
- FIG. 10 shows a two-packed product in which the outer layer gel of Formulation 1 is filled with the inner layer gel of Formulation 10 (a) immediately after filling, (b) 6 hours after filling, (c) 24 hours after filling, ( d) A photographic image showing the state of the preparation 48 hours after filling.
- the hemispherical inner layer gel was encapsulated in the outer layer gel immediately after the filling of the bright purple inner layer gel, but after 6 hours of filling, The boundary with the outer layer gel became unclear, and the hemispherical shape of the inner layer gel could not be confirmed 24 hours after filling.
- FIG. 11 shows the two-packed product in which the outer layer gel of the formulation 1 is filled with the inner layer gel of the formulation 11, (a) immediately after filling the inner layer gel, (b) six hours after filling, (c) 24 hours after filling, d) A photographic image showing the state of the preparation 48 hours after filling.
- the hemispherical inner layer gel was encapsulated in the outer layer gel immediately after filling with the bright yellow-green inner layer gel, but the inner layer gel was 6 hours after filling.
- the boundary between the outer layer gel and the outer layer gel became unclear, and the inner layer gel and the outer layer gel were uniformly mixed after 24 hours of filling.
- FIG. 12 shows a two-packed product in which the outer layer gel of formulation 1 is filled with the inner layer gel of formulation 12, (a) immediately after filling, (b) 6 hours after filling, (c) 24 hours after filling, ( d) A photographic image showing the state of the preparation 48 hours after filling.
- the hemispherical inner layer gel was encapsulated in the outer layer gel immediately after the bright blue inner layer gel was filled, but after 6 hours of filling, the inner layer gel and The boundary with the outer layer gel became unclear, and the hemispherical shape of the inner layer gel could not be confirmed 24 hours after filling.
- FIG. 13 shows a two-packed product in which the outer layer gel of formulation 1 is filled with the inner layer gel of formulation 13, (a) immediately after filling, (b) 6 hours after filling, (c) 24 hours after filling, ( d) A photographic image showing the state of the preparation 48 hours after filling.
- the state in which the bright yellow hemispherical inner layer gel is encapsulated in the outer layer gel is maintained from immediately after filling the inner layer gel to 48 hours after filling, and after 48 hours from filling.
- the boundary between the inner layer gel and the outer layer gel was clear.
- FIG. 14 shows the two-packed product in which the outer layer gel of formulation 1 is filled with the inner layer gel of formulation 14, (a) immediately after filling, (b) 6 hours after filling, (c) 24 hours after filling, ( d) A photographic image showing the state of the preparation 48 hours after filling.
- FIG. 15 shows the two-packed product in which the outer layer gel of formulation 1 is filled with the inner layer gel of formulation 15 (a) immediately after filling, (b) 6 hours after filling, (c) 24 hours after filling, ( d) A photographic image showing the state of the preparation 48 hours after filling.
- FIG. 16 shows the two-packed product in which the outer layer gel of formulation 1 is filled with the inner layer gel of formulation 16, (a) immediately after filling, (b) 6 hours after filling, (c) 24 hours after filling, ( d) A photographic image showing the state of the preparation 48 hours after filling.
- the state in which the black hemispherical inner layer gel is encapsulated in the outer layer gel is maintained from immediately after filling the inner layer gel to 48 hours after the filling, and even after 48 hours after filling, the inner layer is maintained.
- the boundary between the gel and the outer layer gel was clear.
- the inner layer gel is dispersed in the outer layer gel with the passage of time after the inner layer gel is filled, and the state of the two layers can be maintained after 6 hours of filling. lost.
- the inner layer gel and the outer layer gel preparation do not mix even after 48 hours from filling. , Kept two layers.
- the gold colloid of formula 14 was used, the amount of colloid added could be reduced, and the color of the inner layer gel derived from the gold colloid was excellent.
- the inner layer gel is opaque, so the aesthetics are slightly inferior to those of the prescriptions 13 to 15, but the two-layer state of the inner layer gel and the outer layer gel.
- the product has high stability and can be used practically.
- ⁇ Evaluation of formulation functionality> Next, a use test was conducted using a two-packed product using an inner layer gel of Formulations 13 to 15, which had excellent shape retention, and the functionality of the formulation was confirmed. In the use test, the user was instructed to take an appropriate amount of the preparation using a spatula and use it on the skin. After use, interviews were conducted in the form of interviews about its feel and functionality.
- the two-packed product using the inner layer gel of Formulas 13 to 15 includes two types of preparations having the functionality of a cosmetic gel rich in aqueous components and moisturizing components such as glycerin and 1,3-butylene glycol. Yes. Therefore, it was confirmed that a high water retention effect, emollient effect, and moisturizing effect on the skin can be realized when removed with a spatula so as to include the preparation of the outer layer portion and the inner layer portion and applied to the skin. It was also confirmed that the shape of the inner layer and the outer layer was maintained even after a certain amount of the preparation was used, and that it could be used without impairing its aesthetics even during use.
- the inner layer preparation has the functionality of multiple preparations having different functionalities in the inner layer and outer layer, and the inner layer preparation is included in the outer layer preparation. It has been demonstrated that a multilayered state can be stably maintained for a longer period of time and a cosmetic product having an excellent aesthetic appearance can be obtained.
- the inner layer preparation is included in the outer layer preparation.
- a cosmetic that can be stably held for a longer period of time can be provided.
- the cosmetic of the present invention is a cosmetic having excellent aesthetics and a single cosmetic having the functionality of a plurality of preparations.
- the present invention can provide a cosmetic product having the following advantages.
- a plurality of preparations selected from basic cosmetics such as an aqueous gel, an oily gel, a cosmetic gel, an aqueous cleansing gel, and an oily cleansing gel (preferably a plurality of same dosage forms)
- the preparation A and the preparation B having the functionality of two different cosmetics are blended in a separated form. Since the component contained in one preparation does not greatly affect the other preparation, the selectivity of components that can be blended in each preparation is improved.
- the cosmetic product of the present invention two types of preparations that are visually different shapes are separated in a transparent or translucent container, and the internal preparation has a projecting curved surface at least on the surface thereof. Formulated in a state.
- the user can also visually adjust the usage amount of the two types of preparations according to the skin condition at the time of use. That is, the user can use it while visually adjusting it by using many outside preparations or using many inside preparations according to the skin condition. Although it is a single product, it can be used according to the skin condition.
- an aqueous cleansing gel is selected for one of the preparations and an oily cleansing gel is selected for the other of the preparations
- one product can remove aqueous stains and makeup, and oily stains and makeup.
- a new type of cleansing formulation that can be provided.
- the inner layer preparation is completely encased in the outer layer preparation.
- the outflow of the aroma component to the outside of the preparation can be significantly reduced until just before use by blending the aroma component such as fragrance and essential oil only in the preparation of the inner layer portion.
- the cosmetic product of the present invention it is possible to provide a cosmetic product that spreads a fresh scent immediately after production. Furthermore, in the case of a preparation containing an oil component, the possibility of direct contact with air is very low, and oxidation of the oil component inside can be suppressed.
- Cosmetics using a highly transparent aqueous gel as the outer layer formulation and a colored gel as the inner layer formulation are more aesthetically pleasing.
- the mixing ratio of the aqueous gel of the outer layer and the formulation of the inner layer, and the presence or absence of coloring it is possible to provide a product with a beautiful and mysterious shape with a gel-like gel layer wrapped in a gel. it can.
- the present invention can provide cosmetics having aesthetics and various functionalities not found in existing products.
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Abstract
Description
(項目1)
透明または半透明である容器と、該容器内に充填された透明または半透明である製剤Aと、該製剤A内に埋入された製剤Bと、を有する化粧品であって、
該製剤AおよびBの少なくとも一方はコロイドを含む、
化粧品。
(項目2)
前記製剤Aと前記製剤Bとは同一の剤形である、項目1に記載の化粧品。
(項目3)
前記製剤Aおよび前記製剤Bの剤形が水性ゲルである、項目2に記載の化粧品。
(項目4)
前記製剤Bが透明または半透明である、項目1から3のいずれか一項に記載の化粧品。(項目5)
前記製剤Bがコロイドを含み、該製剤B全量に対するコロイド分散液の配合量が0.001~50.00重量%である、項目1から4のいずれか一項に記載の化粧品。
(項目6)
前記コロイドの平均粒径が1nm~10μmである、項目1から5のいずれか一項に記載の化粧品。
(項目7)
前記コロイドが金属コロイドである、項目1から6のいずれか一項に記載の化粧品。
(項目8)
前記金属コロイドが、白金、金、銀、パラジウム、ロジウム、ルテニウム、イリジウムおよびこれらの組み合わせ、および、これらの金属を混合して作成する合金からなる群より選択される金属コロイドである、項目7に記載の化粧品。
(項目9)
前記製剤Aおよび前記製剤Bの以下の条件で測定した製剤の粘性を示す最大荷重が、0.2N~2.0Nである、項目1から8のいずれか一項に記載の化粧品:
株式会社サン科学製のSUN RHEO METER(COMPAC100-II)により測定し、直径20mmの棒状プローブを60mm/minの速度で25mm貫入させた時に棒状プローブの断面積あたりにかかる荷重の最大値を測定する。
(項目10)
製剤全量に対する前記製剤Bの割合が10~60重量%である、項目1から9のいずれか一項に記載の化粧品。
(項目11)
前記製剤Bの形状が、真球状、球状、卵状、偏球状、断面楕円形状、表面に突起のある真球状、表面に突起のある球状、表面に突起のある卵状、表面に突起のある偏球状、表面に突起のある断面楕円形状からなる群から選択される形状である、項目1から10のいずれか一項に記載の化粧品。
<定義>
本明細書において、「剤形が同一である」または「同一の剤形」とは、複数の製剤に関して、同種の基材を用いて作製されたものであることをいう。基材としては、例えば、水溶性基材、油脂性基材、乳剤性基材、ゲル基材(例えば、水性ゲルまたは油性ゲル)等が挙げられるが、これらに限定されない。
<化粧品>
図1(a)~(d)は、本発明の一実施形態に係る化粧品1の種々の形態を示す概略説明図である。図1(a)~(d)に示すように、化粧品1は、透明または半透明である容器2と、容器2内に充填された透明または半透明である製剤Aと、製剤A内に埋入された製剤Bと、を有する。
(1.容器)
容器2としては、その内部に充填される製剤Aおよび製剤Bを外側から見ることができ、通常のクリームやゲルなどの化粧品に使用される容器が好ましい。その形状や素材等は特に限定されない。なお、容器2の形状は、製剤Aおよび製剤Bの充填量、所望の外観等に応じて適宜変更することができる。
(2.製剤)
本実施形態において、製剤Aおよび製剤B(以下、まとめて「製剤」とも称する。)の剤形としては、例えば、ゲル状、クリーム状および半固体等が挙げられるが、これらに限定されない。また、本実施形態において、製剤の色調は特に制限されない。例えば、製剤は、白濁、白色、透明、有色のゲル、もしくは乳化組成物であってもよい。化粧品1の審美性の観点からは、外層の製剤Aは、着色もしくは無着色の透明もしくは半透明のものが望ましく、製剤が水性ゲルの場合は特にそうである。これにより、外層と内層の色調の違いを化粧品1の外部から(容器2の外側から)視認することができるため、化粧品1の美観がより向上する。好ましい実施形態において、製剤Aと製剤Bとは同一の剤形である。
アボガド油、アーモンド油、オリーブ油、つばき油、ごま油、米ぬか油、サフラワー油、大豆油、コーン油、なたね油、キョウニン油、パーシック油、桃仁油、ひまし油、ヒマワリ油、ブドウ種子油、綿実油、ココナッツ油、小麦胚芽油、米胚芽油、月見草油、ハイブリッドヒマワリ油、マカデミアナッツ油、メドウフォーム油、へーゼルナッツ油、パーム核油、パーム油、やし油、カカオ脂、シア脂、木ろう、ミンク油、タートル油、卵黄油、牛脂、乳脂、豚脂、場油等の油脂類;または、ホホバ油、カルナウバろう、キャンデラろう、米ぬかろう、オレンジラフィー油、みつろう、セラック、ラノリン、モンタンろう等のロウ類;または、スクワレン、スクワラン、流動パラフィン、パラフィン、マイクロクリスタリンワックス、ワセリン、軟質流動イソパラフィン、水添ポリイソブチレン、オゾケライト、セレシン、α-オレインフィンオリゴマー、ポリブテン、ポリエチレン等の炭化水素類;または、ラウリン酸、ミリスチン酸、パルミチン酸、ステアリン酸、ベヘン酸、ヒドロキシステアリン酸、オレイン酸、リノール酸、エチルヘキサン酸、イソステアリン酸、イソパルミチン酸、イソトリデカン酸、イソノナン酸、ペンタデカン酸等の高級脂肪酸類;または、ラウリルアルコール、ステアリルアルコール、セテアリルアルコール、ベヘニルアルコール、セタノール、オレイルアルコール、ラノリンアルコール、コレステロール、イソコレステロール、シトステロール、スチグマステロール、イソステアリルアルコール、オクチルドデカノール、ヘキシルデカノール等の高級アルコール類;または、ミリスチン酸イソプロピル、パルミチン酸イソプロピル、ステアリン酸ブチル、オレイン酸エチル、パルミチン酸セチル、ミリスチン酸ミリスチル、ミリスチン酸オクチルドデシル、オレイン酸オクチルドデシル、ステアリン酸コレステリル、ヒドロキシステアリン酸コレステリル、トリカプリン、トリミリスチン、トリ2-エチルヘキサン酸グリセリル(トリオクタノイン)、イソステアリン酸イソプロピル、イソステアリン酸イソプロピル、イソステアリン酸エチル、エチルヘキサン酸セチル、エチルヘキサン酸ステアリル、トリエチルヘキサン酸グリセリル、トリエチルヘキサン酸グリセリル、トリエチルヘキサン酸トリメチロールプロパン、テトラエチルヘキサン酸ペンタエリスリル、トリイソステアリン酸グリセリル、トリイソステアリン酸トリメチロールプロパン、テトライソステアリン酸ペンタエリスチル、トリイソステアリン酸ペンタエリスリル、イソステアリン酸イソセチル、ジメチルオクタン酸オクチルドデシル、乳酸ミリスチル、乳酸セチル、クエン酸トリオクチルドデシル、リンゴ酸ジイソステアリル等のエステル類;ならびにこれらを2種以上含む混合物。
グリセリン、1,3-ブチレングリコール、プロピレングリコール、3-メチル-1,3-ブタンジオール、1,3-プロパンジオール、2-メチル-1,3-プロパンジオール、トリメチロールプロパン、ペンタエリスリトール、ヘキシレングリコール、ジグリセリン、ポリグリセリン、ジエチレングリコール、ポリエチレングリコール、ジプロピレングリコール、ポリプロピレングリコール、エチレングリコール、ジエチレングリコールモノエチルエーテル(エトキシジグリコール)、エチレングリコールモノエチルエーテル、エチレングリコールモノブチルエーテル、ジエチレングリコールジブチルエーテル、ソルビトール、キシリトール、エリスリトール、マンニトール、マルチトール、グルコース、フルクトース、ガラクトース、マンノース、トレオース、キシロース、アラビノース、フコース、リボース、デオキシリボース、マルトース、トレハロース、ラクトース、ラフィノース、グルコン酸、グルクロン酸、シクロデキストリン、β-グルカン、キチン、キトサン、ヘパリンおよびその誘導体、ペクチン、アラビノガラクタン、デキストリン、デキストラン、グリコーゲン、エチルグルコシド、メタクリル酸グルコシルエチル重合物、ヒアルロン酸、ヒアルロン酸ナトリウム、ムコイチン硫酸、カロニン硫酸、ケラト硫酸、デルマタン硫酸、シロキクラゲ抽出物、シロキクラゲ多糖体、チューベロース多糖体、クエン酸、酒石酸、尿素、2-ピロリドン-5-カルボン酸およびそのナトリウム等の塩、ベタイン(トリメチルグリシン)、プロリン、ヒドロキシプロリン、アルギニン、リジン、セリン、グリシン、アラニン、フェニルアラニン、チロシン、β-アラニン、スレオニン、グルタミン酸、グルタミン、アスパラギン、アスパラギン酸、システイン、シスチン、メチオニン、ロイシン、イソロイシン、バリン、トリプトファン、ヒスチジン、タウリン、コラーゲン、アテロコラーゲン、ゼラチン、エラスチン、コラーゲン分解ペプチド、加水分解コラーゲン、塩化ヒドロキシプロピルアンモニウム加水分解コラーゲン、エラスチン分解ペプチド、ケラチン分解ペプチド、加水分解ケラチン、コンキオリン分解ペプチド、加水分解コンキオリン、シルク蛋白分解ペプチド、加水分解シルク、ラウロイル加水分解シルクナトリウム、大豆蛋白分解ペプチド、小麦蛋白分解ペプチド、加水分解小麦蛋白、カゼイン分解ペプチド、アシル化ペプチド等の蛋白ペプチド類およびその誘導体;パルミトイルオリゴペプチド、パルミトイルペンタペプチド、パルミトイルテトラペプチド、乳酸菌培養液、酵母抽出液、卵殻膜タンパク、牛顎下腺ムチン、ヒポタウリン、ゴマリグナン配糖体、グルタチオン、アルブミン、乳清;塩化コリン、ホスホリルコリン;胎盤抽出液、エアラスチン、コラーゲン、アロエ抽出物、ハマメリス水、ヘチマ水、カモミラエキス、カンゾウエキス、コンフリーエキス、シルクエキス、イザヨイバラエキス、セイヨウノコギリソウエキス、ユーカリエキス、メリロートエキス、天然型セラミド(タイプ1、2、3、4、5、6)、ヒドロキシセラミド、スフィンゴ糖脂質。
は、製剤に均一に分散する色素であれば特に限定されない。代表的な色素としては、赤色2号、赤色3号、赤色102号、赤色106号、黄色4号、黄色5号、緑色3号、青色1号、青色2号、赤色201号、赤色213号、赤色214号、赤色227号、赤色231号、赤色232号、だいだい色205号、だいだい色207号、黄色203号、緑色201号、緑色204号、緑色205号、青色202号、青色203号、青色205号、青色205号、かっ色201号、赤色401号、赤色502号、赤色503号、赤色504号、赤色506号、だいだい色402号、黄色402号、黄色406号、黄色407号、緑色401号、緑色402号、紫色401号、黒色401号等の合成着色料の他、クチナシ色素、シアノコバラミン、紫根エキス、アズレンおよびその誘導体、クロロフィルおよびその誘導体、コチニール色素などの色素および着色性の成分が挙げられるがこれらに限定されない。これらの色素は、単独または任意に組み合わせて添加することができる。
<化粧品の製造方法>
次に、本発明の化粧品の製造方法について説明する。本実施形態に係る化粧品1は、まず、外層の製剤Aを容器2内に充填し、次いで、製剤Aの内部に、内層の製剤Bを充填することで製造することができる。製剤Aおよび製剤Bの充填方法としては特に限定されず、それぞれの製剤をそのまま、または回転を加えながら、通常の化粧品の製造工程で使用する充填機もしくは注射器等を用いて充填することができる。
以上、本発明を、理解の容易のために好ましい実施形態を示して説明してきた。以下に、実施例に基づいて本発明を説明するが、上述の説明および以下の実施例は、例示の目的のみに提供され、本発明を限定する目的で提供するものではない。当業者は、発明の具体的な好ましい実施形態の記載から、本発明の記載および技術常識に基づいて等価な範囲を実施することが理解できる。従って、本発明の範囲は、本明細書に具体的に記載された実施形態にも実施例にも限定されず、特許請求の範囲によってのみ限定される。
以下の処方と製造方法により、外層の製剤を調製した。
(処方1:外層の製剤/透明の水性ゲル)
(A)アクリル酸・メタクリル酸アルキル重合体:0.7(重量%)
(B)水酸化カリウム:0.26(重量%)
(A)濃グリセリン:15(重量%)
(A)1,3-ブチレングリコール:5(重量%)
(A)パラオキシ安息香酸メチル:0.15(重量%)
(A)精製水:全量が100(重量%)になるように残量を添加
(調製方法)
成分(A)を攪拌しながら加熱溶解した後、精製水を使って10%に溶解した成分(B)を添加した。その後、攪拌しながら室温まで冷却することで透明のゲルを得た。
(物性値の測定)
処方1のゲル製剤を調製した後、100mlのビーカーに100gとり、24時間、室温にて静置してから、最大荷重と比重を測定した。その結果、最大荷重 0.54N、比重 1.03であった。なお、ゲル製剤の最大荷重は、株式会社サン科学より購入したSUN RHEO METER(COMPAC100-II)により測定し、直径20mmの棒状プローブを60mm/minの速度で25mm貫入させた時に棒状プローブの断面積あたりにかかる荷重の最大値を測定した。
<内層の製剤の調製>
以下の処方と製造方法により、内層の製剤を調製した。
(処方2~16:内層の製剤/有色の水性ゲル)
(A)アクリル酸・メタクリル酸アルキル重合体:0.7(重量%)
(B)水酸化カリウム:0.26(重量%)
(A)濃グリセリン:15(重量%)
(A)1,3-ブチレングリコール:5(重量%)
(A)パラオキシ安息香酸メチル:0.15(重量%)
(C)色素成分またはコロイド(以下の表1に示す)
(A)精製水:全量が100(重量%)になるように残量を添加
(調製方法)
成分(A)を攪拌しながら加熱溶解した後、精製水を使って10%に溶解した成分(B)を添加した。成分(C)の色素を表1に示す添加条件で添加し、撹拌しながら室温まで冷却することで着色ゲルを得た。なお、処方13のプラチナシルバーコロイドは、株式会社Johzen製のプラチナシルバーコロイド500、処方14の金コロイドは、大日本化学工業株式会社製の金コロイドPD-S、処方15のシルバーコロイドは、Sigma-Aldrich Co.Ltd 製のSilver suspensionを使用した。
30g容量の透明樹脂製容器に、処方1の外層ゲル20gをシリンジより充填後、充填した外層ゲルにシリンジの先を差し込みそれぞれ内層ゲル(処方2~16)10gを充填した。
<製剤の形状の保持性の評価>
上記方法にて二種類の異なるゲル製剤を充填した製品(二剤充填製品)を、室温で保存し、内層ゲルの充填直後、充填6時間後、充填24時間後、充填48時間後の製剤の様子を目視観察した。結果を図2~16に示す。
<製剤の機能性の評価>
次に、製剤の形状の保持性に優れていた処方13~15の内層ゲルを用いた二剤充填製品を用いて使用試験を行い、製剤の機能性を確認した。使用試験において、使用者にはヘラを使用して製剤を適量とり、肌へ使用するように指示した。使用後に、その使用感と機能性についてインタビュー形式でヒアリングを行った。
(1)本発明により、1つの製品で、水性ゲル、油性ゲル、美容ゲル、水性クレンジングゲル、油性クレンジングゲルなどの基礎化粧料から選択される複数の製剤(好ましくは、剤形が同一の複数の製剤)の機能性を持つ化粧品を提供することができる。
(2)本発明の化粧品の一実施形態では、2種の異なる化粧料の機能性を有する製剤Aおよび製剤Bが分離した形で配合されている。一方の製剤中に含まれる成分は、他方の製剤に大きく影響を与えることがないので、各製剤中に配合できる成分の選択性が向上する。(3)本発明の化粧品の一実施形態では、視覚的にも異なる形状の二種の製剤が、透明または半透明の容器内に分離し、かつ内部の製剤が少なくともその表面に突曲面を有する状態で配合されている。使用者は使用時の肌の状態等に応じて、視覚的に二種の製剤の使用量を調節して使用することもできる。すなわち、使用者は肌の状況に応じて外側の製剤を多く使用したり、内側の製剤を多く使ったりといった使い方で、視覚的に調整しながら使用することができる。1つの製品でありながら、肌の状態に応じて使い分けができる。
(4)製剤の一方に水性クレンジングゲルを選択し、製剤の他方に油性クレンジングゲルを選択して配合した場合、1つの製品で、水性の汚れやメイクと、油性の汚れやメイクを落とすことができる新しいタイプのクレンジング製剤を提供することができる。
(5)本発明の化粧品の一実施形態では、内層の製剤が完全に外層の製剤で包みこまれた形状である。このような形状をとることで、香料や精油などの香気成分を内層部分の製剤にのみ配合することで、使用直前まで製剤外への香気成分の流出を大幅に低減することができる。本発明の化粧品を使用する時に、製造直後のフレッシュな香りが広がるような化粧品を提供することができる。さらには、油性成分を内包する形状の製剤の場合、空気と直接触れる可能性が極めて少なく、内部の油性成分の酸化を抑えることもできる。
(6)外層の製剤として透明性の高い水性ゲルを使用し、内層の製剤として着色されたゲルを使用した化粧品は、より美観に優れている。容器の形状や外層の水性ゲルと内層の製剤の配合割合や着色の有無によっては、ジェル中にすっぽりと球状のゲル層が包まれた、美観に優れ神秘的な形状の製品を提供することができる。
2 容器
A 外層の製剤
B 内層の製剤
Claims (11)
- 透明または半透明である容器と、該容器内に充填された透明または半透明である製剤Aと、該製剤A内に埋入された製剤Bと、を有する化粧品であって、
該製剤AおよびBの少なくとも一方はコロイドを含む、
化粧品。 - 前記製剤Aと前記製剤Bとは同一の剤形である、請求項1に記載の化粧品。
- 前記製剤Aおよび前記製剤Bの剤形が水性ゲルである、請求項2に記載の化粧品。
- 前記製剤Bが透明または半透明である、請求項1から3のいずれか一項に記載の化粧品。
- 前記製剤Bがコロイドを含み、該製剤B全量に対するコロイド分散液の配合量が0.001~50.00重量%である、請求項1から4のいずれか一項に記載の化粧品。
- 前記コロイドの平均粒径が1nm~10μmである、請求項1から5のいずれか一項に記載の化粧品。
- 前記コロイドが金属コロイドである、請求項1から6のいずれか一項に記載の化粧品。
- 前記金属コロイドが、白金、金、銀、パラジウム、ロジウム、ルテニウム、イリジウムおよびこれらの組み合わせ、および、これらの金属を混合して作成する合金からなる群より選択される金属コロイドである、請求項7に記載の化粧品。
- 前記製剤Aおよび前記製剤Bの以下の条件で測定した製剤の粘性を示す最大荷重が、0.2N~2.0Nである、請求項1から8のいずれか一項に記載の化粧品:
株式会社サン科学製のSUN RHEO METER(COMPAC100-II)により測定し、直径20mmの棒状プローブを60mm/minの速度で25mm貫入させた時に棒状プローブの断面積あたりにかかる荷重の最大値を測定する。 - 製剤全量に対する前記製剤Bの割合が10~60重量%である、請求項1から9のいずれか一項に記載の化粧品。
- 前記製剤Bの形状が、真球状、球状、卵状、偏球状、断面楕円形状、表面に突起のある真球状、表面に突起のある球状、表面に突起のある卵状、表面に突起のある偏球状、表面に突起のある断面楕円形状からなる群から選択される形状である、請求項1から10のいずれか一項に記載の化粧品。
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JPH04178312A (ja) * | 1990-11-08 | 1992-06-25 | Kanebo Ltd | 化粧料 |
JPH07204493A (ja) * | 1994-01-18 | 1995-08-08 | Kanebo Ltd | 金コロイド溶液 |
JP2001122723A (ja) * | 1999-10-27 | 2001-05-08 | I Betsukusu:Kk | 化粧品 |
JP2004162169A (ja) * | 2002-09-26 | 2004-06-10 | Mitsubishi Materials Corp | 安定性の良い金属コロイドとその用途 |
JP2005089337A (ja) * | 2003-09-12 | 2005-04-07 | Shiseido Co Ltd | 多層状透明ゲル組成物及びその製造方法 |
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JP2766329B2 (ja) * | 1989-08-17 | 1998-06-18 | 鐘紡株式会社 | 化粧料 |
US20050087102A1 (en) * | 2003-02-25 | 2005-04-28 | Manfred R. Kuehnle | Encapsulated nanoparticles for the absorption of electromagnetic energy in ultraviolet range |
CN1784201B (zh) * | 2003-05-08 | 2010-05-26 | 宝洁公司 | 包含疏水改性的干涉颜料的个人护理组合物 |
US20040223991A1 (en) * | 2003-05-08 | 2004-11-11 | The Procter & Gamble Company | Multi-phase personal care composition |
US20050208005A1 (en) * | 2003-08-11 | 2005-09-22 | Franck Giroud | Cosmetic composition comprising particles having a core-shell structure |
JP2007326796A (ja) * | 2006-06-06 | 2007-12-20 | Geol Kagaku Kk | 金コロイドを含有する美白剤およびチロシナーゼ阻害剤 |
JP2009221140A (ja) * | 2008-03-14 | 2009-10-01 | National Institute Of Advanced Industrial & Technology | 化粧品用着色ナノ粒子及びその製造方法 |
-
2016
- 2016-03-22 JP JP2016056777A patent/JP6723037B2/ja active Active
-
2017
- 2017-03-13 US US16/083,648 patent/US20190070077A1/en not_active Abandoned
- 2017-03-13 CN CN201780019679.0A patent/CN109069353B/zh active Active
- 2017-03-13 KR KR1020187027217A patent/KR20180110161A/ko not_active IP Right Cessation
- 2017-03-13 WO PCT/JP2017/009975 patent/WO2017163980A1/ja active Application Filing
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JPH04178312A (ja) * | 1990-11-08 | 1992-06-25 | Kanebo Ltd | 化粧料 |
JPH07204493A (ja) * | 1994-01-18 | 1995-08-08 | Kanebo Ltd | 金コロイド溶液 |
JP2001122723A (ja) * | 1999-10-27 | 2001-05-08 | I Betsukusu:Kk | 化粧品 |
JP2004162169A (ja) * | 2002-09-26 | 2004-06-10 | Mitsubishi Materials Corp | 安定性の良い金属コロイドとその用途 |
JP2005089337A (ja) * | 2003-09-12 | 2005-04-07 | Shiseido Co Ltd | 多層状透明ゲル組成物及びその製造方法 |
JP2006124826A (ja) * | 2004-09-29 | 2006-05-18 | Mitsubishi Materials Corp | 金属コロイド粒子及び金属コロイド並びに該金属コロイドの用途 |
JP2011006374A (ja) * | 2009-06-29 | 2011-01-13 | Geol Kagaku Kk | 化粧品 |
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CN110693759A (zh) * | 2019-11-19 | 2020-01-17 | 辽宁燕阳医疗设备有限公司 | 一种抗衰老化妆品及其制备方法 |
Also Published As
Publication number | Publication date |
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CN109069353B (zh) | 2021-11-30 |
CN109069353A (zh) | 2018-12-21 |
KR20180110161A (ko) | 2018-10-08 |
JP2017171586A (ja) | 2017-09-28 |
US20190070077A1 (en) | 2019-03-07 |
JP6723037B2 (ja) | 2020-07-15 |
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