WO2017135279A1 - Appareil de gestion d'administration de médicament, procédé de gestion d'administration de médicament, et système de gestion d'administration de médicament - Google Patents

Appareil de gestion d'administration de médicament, procédé de gestion d'administration de médicament, et système de gestion d'administration de médicament Download PDF

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Publication number
WO2017135279A1
WO2017135279A1 PCT/JP2017/003543 JP2017003543W WO2017135279A1 WO 2017135279 A1 WO2017135279 A1 WO 2017135279A1 JP 2017003543 W JP2017003543 W JP 2017003543W WO 2017135279 A1 WO2017135279 A1 WO 2017135279A1
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WO
WIPO (PCT)
Prior art keywords
medication
container
medicine
sensor
predetermined
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PCT/JP2017/003543
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English (en)
Japanese (ja)
Inventor
涼一 徳元
保夫 植村
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株式会社日立製作所
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Publication of WO2017135279A1 publication Critical patent/WO2017135279A1/fr

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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61J—CONTAINERS SPECIALLY ADAPTED FOR MEDICAL OR PHARMACEUTICAL PURPOSES; DEVICES OR METHODS SPECIALLY ADAPTED FOR BRINGING PHARMACEUTICAL PRODUCTS INTO PARTICULAR PHYSICAL OR ADMINISTERING FORMS; DEVICES FOR ADMINISTERING FOOD OR MEDICINES ORALLY; BABY COMFORTERS; DEVICES FOR RECEIVING SPITTLE
    • A61J7/00—Devices for administering medicines orally, e.g. spoons; Pill counting devices; Arrangements for time indication or reminder for taking medicine
    • A61J7/04—Arrangements for time indication or reminder for taking medicine, e.g. programmed dispensers
    • G—PHYSICS
    • G16—INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR SPECIFIC APPLICATION FIELDS
    • G16H—HEALTHCARE INFORMATICS, i.e. INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR THE HANDLING OR PROCESSING OF MEDICAL OR HEALTHCARE DATA
    • G16H10/00—ICT specially adapted for the handling or processing of patient-related medical or healthcare data
    • G16H10/60—ICT specially adapted for the handling or processing of patient-related medical or healthcare data for patient-specific data, e.g. for electronic patient records
    • G—PHYSICS
    • G16—INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR SPECIFIC APPLICATION FIELDS
    • G16H—HEALTHCARE INFORMATICS, i.e. INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR THE HANDLING OR PROCESSING OF MEDICAL OR HEALTHCARE DATA
    • G16H20/00—ICT specially adapted for therapies or health-improving plans, e.g. for handling prescriptions, for steering therapy or for monitoring patient compliance
    • G16H20/10—ICT specially adapted for therapies or health-improving plans, e.g. for handling prescriptions, for steering therapy or for monitoring patient compliance relating to drugs or medications, e.g. for ensuring correct administration to patients

Definitions

  • the present invention relates to a medication management device, a medication management method, and a medication management system, and specifically, a technique for managing a medication history with good accuracy according to medication operation and supporting quick and accurate medication guidance. About.
  • a medicine package storage unit having a plurality of blocks for storing a medicine package containing a medicine used by a user at a time in one block, and a plurality of times of taking medicine Storage means for storing in advance, medication time notifying means for notifying that the medication time has arrived each time the medication time has arrived, and a medicine package sensor for detecting the presence or absence of a medicine package in the block of the medicine package storage unit
  • the medicine pack sensor determines the presence or absence of a medicine package of a predetermined block, stores the time and the presence or absence of the medicine package in the storage means, and instructs the user according to the detection result
  • the storage means stores the time and the effect of the removal, and the user
  • a medicine managing apparatus and a second processing means for outputting a desired instruction see Patent Document 1 it has been proposed.
  • the effect of suppressing forgetting to take medication can be expected by notification according to the schedule.
  • various forms of medicines and it is difficult to accurately grasp the medication operation based on the presence or absence of medicines in the storage unit.
  • the medical history, dispensing pharmacies, pharmaceutical companies, etc. will grasp the medication history immediately and respond to the need to provide timely medication guidance according to the content. Is not done.
  • an object of the present invention is to provide a technique for managing a medication history with good accuracy according to a medication operation and supporting prompt and accurate medication guidance.
  • the medication management apparatus of the present invention that solves the above-described problems is a sensor that detects one or more medication operations of a medication person with respect to a medicine container, and a detection result by the sensor is transmitted to an external device via a predetermined network. And a communication device for transmission.
  • the medication management system of the present invention includes a sensor for detecting one or more medication operations of a medication person with respect to a medicine container, and communication for transmitting a detection result by the sensor to an external device via a predetermined network.
  • a medication management device comprising a device; and receiving the detection result, and associating each identification information of the medication subject to be managed and the medicine indicated by the detection result, and each value of the medication operation, and storing it as a medication history
  • a terminal that stores the medication history in response to a request from any one of a medical institution, a pharmaceutical company, and a dispensing pharmacy, or at the elapse of a predetermined period, at least among the terminals.
  • a server for delivering to the server.
  • the medication management method of the present invention includes an information processing device including a communication device that performs communication in a predetermined network and a sensor that detects one or a plurality of medication operations of a medication person with respect to a medicine container. The detection result by the sensor is transmitted to the server via the network.
  • the present invention it is possible to manage a medication history with good accuracy according to the medication operation, and to support prompt and accurate medication guidance.
  • FIG. 1 is a network configuration diagram including a medication management system 10 of the present embodiment.
  • a medication management system 10 shown in FIG. 1 includes a medication management device 100 and a server 200.
  • the medication management device 100 is a computer that manages a medication history with good accuracy according to the medication operation in the container 3 and supports prompt and accurate medication guidance.
  • the medication management apparatus 100 assumes a computer chip attached to a medicine container 3 (eg, eye drop container) to be taken by a patient.
  • a medicine container 3 eg, eye drop container
  • the server 200 is communicably connected to the medication management apparatus 100 through an appropriate communication resource such as the network 20.
  • the server 200 is a server device that collects, manages, and distributes information related to medication from the medication management device 100 of each medication person.
  • the server 200 is also connected to the medical institution terminal 300, the pharmaceutical company terminal 400, the dispensing pharmacy terminal 500, and the family terminal 600 via the network 20 described above.
  • the medical institution terminal 300 obtains a medication history from the server 200 for a patient to be prescribed by the medical institution, that is, a medication taker, and provides information such as medication guidance and medication supplementation to the medication taker based on the history. An information processing terminal to be returned to the server 200.
  • the pharmaceutical company terminal 400 is a terminal managed and operated by the pharmaceutical company.
  • the pharmaceutical company terminal 400 obtains a medication history from the server 200 regarding the drug taker of the drug of the pharmaceutical company, and appropriately stores information for business operations such as grasping the actual use of the drug and improving the drug based on the history.
  • An information processing terminal that generates or outputs.
  • the dispensing pharmacy terminal 500 is a terminal managed and operated by the dispensing pharmacy.
  • the dispensing pharmacy terminal 500 obtains a medication history from the server 200 regarding the medication recipient of the medication dispensed by the dispensing pharmacy, and provides information such as medication guidance and medication supplementation to the medication recipient based on this history to the server 200 described above. Information processing terminal to return.
  • the family terminal 600 is a terminal used by the above-mentioned patient's family.
  • the family terminal 600 can be assumed to be a mobile terminal such as a smartphone.
  • the family terminal 600 outputs various information distributed from the server 200 to an appropriate output device such as a display or a speaker, and notifies the above-mentioned family of the patient's medication status and safety confirmation information. It becomes.
  • the medication management system 10 includes at least one of the medical institution terminal 300, the pharmaceutical company terminal 400, the dispensing pharmacy terminal 500, and the family terminal 600 in addition to the medication management apparatus 100 and the server 200. Further, it may be included.
  • the medication management apparatus 100 stores a memory device 101 composed of an appropriate nonvolatile memory element such as a flash memory, a memory 103 composed of a volatile memory element such as a RAM, and a program 102 held in the memory device 101.
  • the server 200 is connected to the arithmetic device 104 such as a CPU that performs various determinations, computations, and control processes, the output device 105 that performs processing data output processing, and the network 20.
  • the communication device 106 is responsible for the communication process.
  • the above-described output device 105 includes at least a display 1051, an LED lamp 1052, a speaker 1053, and a vibrator 1054.
  • the specific configuration of the above-described communication device 106 is not particularly limited, an appropriate communication unit according to the protocol of the communication path to be employed is used.
  • an appropriate communication unit according to the protocol of the communication path to be employed is used.
  • the device 106 is a Bluetooth (registered trademark) unit.
  • the communication device 106 may be assumed to be a communication chip that performs communication by accessing an appropriate public network such as a mobile phone network.
  • the communication device 106 may support not only wireless communication as described above, but also communication corresponding to wired connection.
  • the communication device 106 is a USB communication unit.
  • the communication method and communication method are not limited.
  • the medication management apparatus 100 further includes an interface 107 and a sensor 110.
  • the interface 107 and the sensor 110 may not be included in the configuration of the medication management device 100, but may be configured as an external device connected to be able to exchange data via an appropriate internal communication line such as BUS.
  • the interface 107 in this embodiment includes a medication button 1071, a non-medication button 1072, a snooze button 1073, and a manner button 1074 as an example.
  • the medication button 1071 and the non-medication button 1072 are interfaces for accepting an indication of intention of taking or not taking medicine.
  • the drug taker simply wants to visually check the stored medicine and does not intend to take the medicine. Exists.
  • the drug taker presses the non-medicine button 1072 out of the above-mentioned drug button 1071 and non-medicine button 1072. That is, it can be clearly stated that “the container 3 has been opened but there is no intention to take medicine”.
  • the medication management apparatus 100 receives an event of pressing the non-medicine button 1072, and transmits it to the server 200 in association with the detection result (at least the operation of the opening / closing structure) of the sensor 110.
  • the medication management device 100 or the server 200 outputs an alert of medication timing according to the medication schedule (for example, output of voice or music prompting medication on the speaker 1053 of the medication management device 100, or a predetermined message on the display 1051) It is also possible to perform control such that the above-described alert output is continued if the patient does not press the medication button 1071 when a display or lighting with a specific pattern of a specific color in the LED lamp 1052 is performed. In this case, in response to the pressing event of the non-medication button 1072, the medication management apparatus 100 stops alert output by itself or transmits an alert output stop notification to the server 200.
  • the medication schedule for example, output of voice or music prompting medication on the speaker 1053 of the medication management device 100, or a predetermined message on the display 1051
  • the medication management apparatus 100 stops alert output by itself or transmits an alert output stop notification to the server 200.
  • the medication management apparatus 100 receives the event of pressing the snooze button 1073 and sets the alert output stop by itself and the alert re-output after a predetermined time, or the alert output stop and the alert re-output after the predetermined time.
  • a request notification is transmitted to the server 200.
  • the manner button 1074 is a button for accepting an instruction to stop alert output from the speaker 1053.
  • the medication management apparatus 100 stops at least the speaker 1053 from outputting the current or subsequent alerts by itself or transmits a notification of the alert output from the speaker 1053 to the server 200.
  • the alert output itself is replaced with the occurrence of vibration in the vibrator 1054 when the manner button 1074 is pressed. Therefore, in this case, the medication management apparatus 100 receives the event of the manner button 1074 and executes the vibration generation corresponding to the current or subsequent alert output by the vibrator 1054 or notifies the server 200 of the vibration generation request notification. Send.
  • the interface 107 As another configuration of the interface 107, it is possible to assume a configuration in which only one button is arranged instead of the two buttons configuration of the medication button 1071 and the non-medication 1072 as described above.
  • the specific action by the drug taker for the one button eg, long press for a predetermined time, multiple presses within a predetermined time, etc.
  • the specific action is “with drug intention” or “without drug intention” Any of these may be indicated.
  • the sensor 110 in the present embodiment detects one or a plurality of medication operations of the medication person with respect to the medicine container 3.
  • the sensor 110 of the present embodiment includes an open / close sensor 111, a passage sensor 112, a rotation sensor 113, a pressing sensor 114, a liquid level sensor 115, and an installation sensor 116.
  • the opening / closing sensor 111 is a sensor that detects an operation in the opening / closing structure of the opening of the container 3. A specific configuration of the open / close sensor 111 will be described later.
  • the passage sensor 112 is a sensor that detects a passage event near the opening when the medicine in the container 3 moves from the opening to the outside of the container. A specific configuration of the passage sensor 112 will be described later.
  • the rotation sensor 113 detects the rotation of the container 3 for moving the medicine in the container 3 from the opening to the outside of the container. A specific configuration of the rotation sensor 113 will be described later.
  • the press sensor 114 detects the press with respect to the predetermined location of the container 3 for moving the chemical
  • the liquid level sensor 115 detects the position of the medicine surface in the container 3.
  • the liquid level sensor 115 may employ existing technology. Specifically, the so-called float type (using floating floating on the liquid surface), ultrasonic type (observing the reflection phenomenon of ultrasonic waves applied to the liquid level), capacitance type (the principle of dielectric constant of the liquid) ) And pressure methods (using the principle of liquid pressure (water pressure)) may be adopted as appropriate.
  • the installation sensor 116 is for detecting, for example, a pressure on the bottom 41 of the housing interior space 4 in order to detect the storage state of the medicine in the housing body space 4.
  • the device ID 120, the user ID 121, the medicine ID 122, the medicine initial registration date and time 123, and the detection result A table 125 is stored at least.
  • the device ID 120 is identification information that uniquely identifies the medication management apparatus 100.
  • the user ID 121 is identification information for uniquely identifying a drug taker who is a user of the drug management device 100 (the container 3 in which the drug management device 100 is installed).
  • the medicine ID 122 is identification information for uniquely identifying the medicine (stored in the container 3) that is the subject of medication management by the medication management apparatus 100.
  • the drug initial registration date and time 123 is the date and time when the drug corresponding to the above-described drug ID is the subject of medication management.
  • the above-described device ID 120, user ID 121, drug ID 122, and drug initial registration date and time 123 are set in advance by, for example, the administrator of the medication management apparatus 100.
  • the detection result table 125 is a table that stores the detection results obtained by the sensor 110 described above. Details of the data structure in the detection result table 125 will be described later.
  • FIG. 3A is a diagram illustrating Example 1 of the container 3 in which the medication management device 100 of the present embodiment is installed
  • FIG. 3B is a diagram illustrating the configuration and operation example 1 of the sensor 110 in the container 3 of the present embodiment. is there.
  • the container 3 shown in FIG. 3A is a pill case or the like that houses the solid medicine 1 such as a capsule or a tablet in the inner space 4.
  • the container 3 includes a lid 5 hinged to the container body 7 as the opening / closing structure 2.
  • an open / close sensor 111, a medication button 1071, and a non-medication button 1072 are installed on the operation panel 6 at a position where it can come into contact with the inner surface of the lid 5.
  • the medication management apparatus 100 which is a computer chip is attached to the front surface 72 of the container main body 7, for example.
  • the open / close sensor 111 includes a spring 1113 embedded in the operation panel 6, a switch body 1111 disposed on the upper end surface of the spring 1113, and a bottom side surface of the switch body 1111.
  • the projecting electrode 1114 and the electrode 1115 locked to the back surface of the operation panel 6 are configured.
  • Electric wires 1117 and 1118 are connected to the electrode 1114 and the electrode 1115, respectively, and ends of the electric wires are connected to the medication management apparatus 100.
  • the lid 5 in the opening / closing structure 2 opens the opening 9 in the inner space 4 by the patient, that is, performs an opening operation.
  • the lid 5 moves in a direction away from the top end surface 1112 of the switch body 1111 of the open / close sensor 111 and moves upward to allow the spring body 1113 to protrude upward.
  • the electrode 1114 also moves upward.
  • the switch body 1111 Prior to this opening operation, the switch body 1111 is pushed downward by the lid 5, and the electrode 1115 on the back surface of the operation panel 6 and the electrode 1114 of the switch body 1111 are separated from each other and become a non-energized state. It was.
  • the above-described non-energized state is canceled and the energized state is established.
  • the medication management apparatus 100 detects the cancellation of this non-energized state in the open / close sensor 111 as an open operation that directly corresponds to the medication operation by the medication person among the open / close operations in the container 3.
  • it is necessary is just to employ
  • the medication management apparatus 100 waits for the medication person to press the medication button 1071 and the non-medicine button 1072 when the opening operation using the open / close sensor 111 is detected. That is, the medication management apparatus 100 is suitable if the medication recipient specifies the event of opening the lid 5 and opening the opening 9 in the inner space 4 but does not easily determine the medication intention. Therefore, if the medication button 1071 is pressed together with the detection of the opening operation, the medication management apparatus 100 identifies “medical intention”.
  • the medication management apparatus 100 when the medication management apparatus 100 outputs an alert about the arrival of the medication timing according to the medication schedule for the medication recipient managed by the server 200 or the device itself, the medication management device 100 does not detect the depression of the medication button 1071 for a certain period of time. It may be possible to strongly encourage the patient to take the medicine by performing control such that the alert is continuously output.
  • FIGS. 3C to 3E another example of the container 3 shown in FIGS. 3A to 3B is shown in FIGS. 3C to 3E.
  • the container 3 has the same basic structure as that shown in FIGS. 3A to 3B.
  • a display 1051, a speaker 1053, a vibrator 1054, a snooze button 1073, and a manner button 1074 are installed on the front surface 72 of the container body 7, in addition to the medication management apparatus 100.
  • an LED lamp 1052 is installed on the surface of the lid 5 of the container.
  • a connecting structure 71 is installed on the side surface 73 of the container body 7.
  • an installation sensor 116 for detecting whether or not the medicine 1 is stored is installed on the bottom surface 41 of the inner space 4.
  • the alert output of the medication timing according to the medication schedule by the medication management device 100 or the server 200 is output from the speaker 1053 as voice or music prompting medication, or a predetermined message prompting medication Can be output from the display 1051 or can be output from the LED lamp 1052 as lighting with a specific pattern of a specific color that prompts medication.
  • these output devices 105 not only one of these output devices 105 but also a plurality or all of them may be combined to output an alert.
  • the above-described alert output can be controlled if the patient does not press the medication button 1071.
  • the medication management apparatus 100 stops alert output by itself or transmits an alert output stop notification to the server 200.
  • the above alert output is made, if the drug taker presses the snooze button 1073, the above alert output is re-executed after a predetermined time (eg, after 5 minutes). You can also.
  • the medication management apparatus 100 receives the event of pressing the snooze button 1073 and sets the alert output stop by itself and the alert re-output after a predetermined time, or the alert output stop and the alert re-output after the predetermined time.
  • a request notification is transmitted to the server 200.
  • the medication management apparatus 100 recognizes that the alert output is stopped by the speaker 1053, and stops the current or subsequent alert output by the speaker 1053, or the alert A stop notification at the output speaker 1053 is transmitted to the server 200.
  • the alert output itself is replaced with the occurrence of vibration in the vibrator 1054 when the manner button 1074 is pressed. Therefore, in this case, the medication management apparatus 100 receives the event of the manner button 1074 and executes the vibration generation corresponding to the current or subsequent alert output by the vibrator 1054 or notifies the server 200 of the vibration generation request notification. Send.
  • the medication management apparatus 100 causes the LED lamp 1052 to blink at a high speed with the arrival of a predetermined time according to the medication timing, and causes the speaker 1053 to output a predetermined sound. Thereafter, when the patient opens the lid 5, the medication management apparatus 100 detects this with the open / close sensor 111, reduces the blinking interval of the LED lamp 1052, makes the transition to slow blinking, and performs a predetermined operation with the speaker 1053. Stop sound output. When the medication person presses the medication button 1071 in a state where the lid 5 is opened, the medication management device 100 turns off the LED lamp 1052 in response to this.
  • the medication management apparatus 100 registers the date and time when the medication user pressed the medication button 1071 in the medication status table 225 (in the case of the medication status table 225 in FIG. 11, registration of “instilled date and time”). Note that the non-medication button 1072 may be unnecessary when such alert output is performed.
  • the container 3 of the present embodiment includes a connecting structure 71 on the side surface 73 thereof.
  • a connecting structure 71 on the side surface 73 thereof.
  • the connection structure 71 for example, a magnet or a set of a fitting hole and a hook can be assumed.
  • any connecting means that integrates the containers 3 with sufficient strength when the side surfaces 73 of the containers 3 are brought into contact with each other may be used.
  • the medication management device 100 shall perform a corresponding operation.
  • the medicine “A” is contained in one container 3 and the medicine “B” is contained in the other container 3.
  • medicines “A” and “B” need to be taken after a certain time.
  • the medication management apparatus 100 starts a timer at a necessary time interval (for example, 5 minutes) when an alert is output from one container 3 and the medication button 1071 is pressed.
  • the medication management apparatus 100 senses that the necessary time interval has been secured by the operation of this timer, executes an alert output in the other container 3, and prompts the subject to take medication “B”.
  • the empty body 4 may be configured by a plurality of compartments 42 as illustrated in FIG. 3G.
  • the internal space 4 is divided into eight sections 42 “1” to “8”.
  • one week's worth of medicine 1 is stored in the section 42 corresponding to each day of the week. Can be assumed.
  • the opening / closing sensor 111 is not necessary in the container 3.
  • the medication management apparatus 100 stores the medicine 1 for Monday in the “1" section 42, the medicine 1 for Tuesday in the “2” section 42, and the medicine 1 for Wednesday in the “42" section 42, Drug 1 for Thursday is in the section 42 for Friday, Drug 1 for Friday is in the section 42 for "5", Drug 1 for Saturday is in the section 42 for "6", Drug 1 for Sunday is "7" It is assumed that each is accommodated in the section 42.
  • the medication management apparatus 100 outputs a message such as “Please take the first medicine” on the display 1051 or the speaker 1053 or a specific color on the LED lamp 1052 with the arrival of a predetermined time on Monday.
  • An alert output such as blinking (in this case, the color of each section corresponds to the display color on the LED lamp 1052) is performed.
  • the drug taker recognizes such an alert, takes out the drug 1 from the corresponding section 42 and takes it, and presses the drug button 1071.
  • the medication management apparatus 100 registers, in the medication status table 225, the date and time when the medication user presses the medication button 1071 in accordance with this depression.
  • the container 3 illustrated in FIGS. 3A and 3B was assumed to be a pill case or the like that contains the solid medicine 1.
  • the container 3 shown in FIGS. 4A and 4B is an eye drop container or the like that stores the liquid medicine 1 such as eye drops in the inner space 4.
  • FIG. 4A is a diagram showing a second example of the container 3 in which the medication management device 100 of the present embodiment is installed
  • FIG. 4B is a diagram showing a second example of the configuration and operation of the sensor 110 in the container 3 of the present embodiment. is there.
  • the container 3 includes, as the opening / closing structure 2, a cap 5 that is screwed into the convex portion 8 of the container body 7 and opens and closes the opening 9 provided at the tip of the convex portion 8.
  • an open / close sensor 111 is installed on the upper end surface of the container body 7 at a position where it can come into contact with the lower end surface of the cap 5.
  • the medication management apparatus 100 which is a computer chip is attached to the upper end surface of the container main body 7, for example.
  • the inner space 4 of the container 3 is provided with a liquid level sensor 115 for detecting the liquid level of the medicine 1 such as eye drops.
  • the open / close sensor 111 includes an electrode 1115 on the upper surface of the recess 1116 provided in the lower end of the cap 5, a spring 1113 erected on the upper end surface of the container body 7, and the spring
  • the switch body 1111 is arranged on the upper end surface of 1113, and the electrode 1114 installed on the upper end surface of the switch body 1111.
  • Electric wires 1117 and 1118 are connected to the electrode 1114 and the electrode 1115, respectively, and ends of the electric wires are connected to the medication management apparatus 100.
  • the cap 5 in the open / close structure 2 is unscrewed from the convex portion 8 by the drug taker, that is, the opening 9 is opened.
  • the cap 5 is separated upward from the switch body 1111 of the open / close sensor 111.
  • the switch body 1111 is pushed downward by the electrode 1115 of the cap 5, and the electrode 1115 of the cap 5 and the electrode 1114 of the switch body 1111 are in contact with each other, It was.
  • the electrode 1115 is moved upward together with the cap 5 by the opening operation described above, and the electrode 1114 that has been in contact with the electrode 1115 is separated, so that the above-described energized state is canceled and the non-energized state is established.
  • the medication management apparatus 100 detects the cancellation of the energized state in the open / close sensor 111 as an open operation that directly corresponds to the medication operation by the medication person among the open / close operations in the container 3.
  • it is necessary is just to employ
  • the container 3 is an eye drop container, it is difficult to assume an operation of separating the cap 5 from the convex portion 8 other than the eye drop. Therefore, unlike the case of the container 3 of the solid medicine 1 described above, the control of waiting for pressing of the medication button 1071 and the non-medication button 1072 may be omitted. However, it is possible to specify the medication intention with higher accuracy by using the rotation sensor 113 described below together.
  • FIG. 5 is a diagram showing a third example of sensor configuration and operation in the container of the present embodiment.
  • the passage sensor 112 detects an event in which the liquid medicine 1 in the inner space 4 passes through the vicinity of the opening in the convex portion 8 when moving from the opening 9 to the outside of the container.
  • the passage sensor 112 is configured by the electrodes 1121 and 1122 that are erected with a predetermined gap on the inner cross section of the convex portion 8.
  • the ends of the electrodes 1121 and 1122 are connected to the medication management apparatus 100 via electric wires 1117 and 1118, respectively.
  • the medication management apparatus 100 which is the connection destination of the edge part of the electric wire 1118, in the said figure, it showed with the broken line for convenience.
  • the liquid medicine 1 is difficult to move toward the opening 9. Therefore, if the liquid drug 1 does not pass through the gap between the electrodes 1121 and 1122, the gap is filled with air having low electrical conductivity, and no current is passed between the electrodes 1121 and 1122. That is, it remains in a non-energized state.
  • the liquid medicine 1 is likely to move toward the opening 9 due to rotation or pressing of the container 3 by the drug taker. .
  • the liquid medicine 1 passes through the gap between the electrodes 1121 and 1122, electricity is passed between the electrodes 1121 and 1122 due to the electrical conductivity of the liquid medicine 1 passing through the gap, and the non-energized state is eliminated.
  • the medication management apparatus 100 detects the cancellation of the non-energized state in the passage sensor 112 as an operation that directly corresponds to the medication operation performed by the medication person, that is, the liquid medication 1 is discharged from the opening 9 of the container 3. To do. In addition, what is necessary is just to employ
  • the rotation sensor 113 is a sensor installed at the bottom 41 in the inner space 4 of the container 3 and detects a change in posture such that the container 3 is upside down. Specifically, an existing posture detection sensor using a pendulum, a gyro, or the like may be employed. The value observed by the rotation sensor 113 is transmitted to the medication management apparatus 100 via a predetermined route.
  • the press sensor 114 detects a pressing operation by a drug taker on a predetermined portion such as the outer peripheral side surface of the container 3.
  • a configuration in which a pressure sensor is attached to the outer periphery of the container 3 may be employed.
  • the medication management apparatus 100 obtains the values observed by the rotation sensor 113 and the pressure sensor 114, that is, the posture of the container 3 and the value of the pressing force applied to the container 3, and has already obtained the convex portion 8. Following the separation of the cap 5 from the container, the container 3 is rotated (for example, rotated so that the top and bottom are reversed) and the side surface of the container is pressed (this reduces the volume of the container body, and the reduced volume The medicine is discharged from the opening).
  • the attitude value of the container 3 observed by the rotation sensor 113 is a default value (the container 3 has the inner bottom 41 downward and the opening 9 is the apex). Observation value of the rotation sensor 113 in a standing state), but a predetermined value (observation value of the rotation sensor 113 in an inverted state in which the container 3 has the opening 9 downward and the inner bottom 41 is the apex) If it is, the turning operation in which the container 3 is inverted is specified.
  • the value of the pressing force observed by the pressing sensor 114 exceeds a predetermined threshold value (this threshold value has been exceeded).
  • this threshold value has been exceeded.
  • the configuration shown in FIGS. 6A to 6B can also be assumed as a modified example of the container 3 that contains the eye drop that is the medicine 1.
  • the container 3 in this case includes an open / close sensor 111, a display 1051, an LED lamp 1052, a speaker 1053, a snooze button 1073, and a manner button 1074, similar to the container 3 illustrated in FIGS. 3C to 3E.
  • the container 3 in the present embodiment includes a support plate 31 for placing the eye drop bottle 1A, a fixing hook 32 for binding the eye drop bottle 1A placed on the support plate 31 to the container 3, and A retrofit cap 5 (lid 5) for accommodating the cap of the eye drop bottle 1A is further provided.
  • the retrofitted cap 5 is an opening / closing structure 2 and has a structure that fits or is screwed to the original cap of the bottle 1A.
  • the alert output itself is the same as that of the container 3 illustrated in FIGS. 3C to 3E, but the medicine button 1071 and the non-medication button 1072 are It is not provided, and the medication operation is sensed by sensing the opening / closing sensor 111 that the retrofitted cap 5 has been removed from the eye drop bottle 1A, that is, the presence of the retrofitted cap 5 has become undetectable.
  • the rotation sensor 113 may detect that the container 3, that is, the eye drop bottle 1 ⁇ / b> A is turned upside down, and detect the medication operation.
  • the configurations of FIGS. 6C to 6D can be assumed.
  • the container 3 in this case is an eye drop assisting tool. Therefore, the container 3 in the present embodiment includes the eye drop lever 33 that is responsible for the operation of releasing the medicine from the eye drop bottle 1A.
  • the eye drop lever 33 is the same as that provided in the existing eye drop assisting tool.
  • 1 A of eye drop bottles will be mounted
  • the container 3 includes an open / close sensor 111 and a rotation sensor 113 as sensors in addition to the above-described retrofitting cap 5, and an LED lamp 1052, a speaker 1053, and a manner button 1074 as the output device 105. ing.
  • the alert output itself is the same as that of the container 3 illustrated in FIGS. 3C to 3E, but the retrofitting cap 5 is used to detect the medication operation.
  • the rotation sensor 113 detects that the container 3, that is, the eye drop bottle 1 ⁇ / b> A is turned upside down. Or at least one of sensing a lever gripping operation of the eye drop lever 33 (in this case, a sensor for the sensing is separately provided) and sensing depression of the medication button 1071. Shall.
  • the medication management apparatus 100 applies the eye drop to be applied next when a predetermined time elapses after detection of eye drops by the predetermined eye drop bottle 1A, that is, medication.
  • Information indicating that the bottle 1A should be set in the container 3 may be output by the output device 105.
  • the container 3 is a pouch-type pill case.
  • an opening / closing sensor 111 for sensing the opening / closing of the zip 34 in addition to the medication management device 100, an opening / closing sensor 111 for sensing the opening / closing of the zip 34, a medication button 1071, a non-medicine button 1072, an LED lamp 1052, a speaker 1053, and a manner button 1074 are provided. It is equipped.
  • the alert output itself is the same as that of the container 3 illustrated in FIGS. 3C to 3E, but the detection of the medication operation is performed when the zip 34 is opened. It is assumed that the detection is performed by at least one of sensing with a predetermined opening / closing sensor 111 and sensing depression of the medication button 1071.
  • the medication management apparatus 100 When a plurality of medicines 1 are subject to medication management, the medication management apparatus 100 contains a medicine 1 to be taken next when a predetermined time has elapsed after detection of medication of the prescribed medicine 1. Information indicating that it should be set to 3 may be output by the output device 105. When a plurality of medicines 1 are stored in the container 3 at the same time, the medication management apparatus 100 outputs an alert output according to the arrival timing of the prescribed medicine 1 at a specific color in the LED lamp 1052. It may be performed by displaying or outputting a predetermined message from the speaker 1053.
  • FIG. 8 is a diagram illustrating a hardware configuration example of the server 200 in the present embodiment.
  • the server 200 includes a storage device 201 configured with an appropriate nonvolatile storage element such as an SSD or a hard disk drive, a memory 203 configured with a volatile storage element such as a RAM, and a program 202 held in the storage device 201.
  • An arithmetic device 204 such as a CPU that performs various determinations, computations, and control processes while performing overall control of the device itself by reading it into the memory 203 and the like, a communication device 205 that is connected to the network 20 and is responsible for communication processing with other devices, Is provided.
  • the storage device 201 stores at least a medication status table 225, a medication information table 226, and a notification information table 227, in addition to the program 202 for implementing functions necessary as the server 200 of the present embodiment. Yes. Details of the data structure of each table will be described later.
  • FIG. 9 shows an example of the detection result table 125 in the present embodiment.
  • the medicine 1 is an eye drop
  • the container 3 is an eye drop container (the same applies hereinafter).
  • the detection result table 125 is a table in which the medication management apparatus 100 stores observation values obtained by the sensor 110.
  • the data structure is a collection of records composed of data such as medication / non-medication, passage, rotation, pressure, and liquid level, with detection date and time obtained from the sensor 110 as a key.
  • “medication / non-medication” is an observed value of a pressing event for the medication button 1071 and the non-medication button 1072 in the container 3. For example, when the medication button 1071 is pressed, “1” indicating that there is a medication intention in the operation of the medication recipient is given.
  • the passage is a value indicating that the passage event of the liquid medicine 1 by the passage sensor 112 is detected within a predetermined time from the detection of the above-mentioned medication / non-medication, and corresponds to the value of the number of times of detection within the predetermined time. . For example, when a passage event is observed twice by the passage sensor 112 within a predetermined number of seconds within a predetermined time from the detection of the above-mentioned medication / non-medication, “2” indicating the number of times the liquid medicine 1 has been ejected from the opening 9. ", Is given.
  • the rotation corresponds to the value of the number of rotations of the container 3 detected by the rotation sensor 113 within a predetermined time from the detection of the above-mentioned medication / non-medication. For example, when a rotation event of the container 3 is observed twice by the rotation sensor 113 within a predetermined number of seconds from the detection of the above-mentioned medication / non-medication, the container 3 as an eye drop container is instilled. Therefore, “2” indicating the number of rotations is given.
  • the pressing corresponds to the number of times that the pressing force against the container 3 is detected within a predetermined time by the pressing sensor 114 within a predetermined time from the detection of the above-mentioned medication / non-medication. For example, if the pressure sensor 114 detects twice a pressure greater than or equal to a predetermined threshold value within a predetermined number of seconds within a predetermined time from the detection of the above-mentioned medication / non-medication, the side surface of the container 3 that is an eye drop container “2” indicating the number of times that is pressed twice for instillation is given.
  • the liquid level corresponds to the liquid level decrease value of the liquid medicine 1 in the inner space 4 of the container 3 detected within the predetermined time by the liquid level sensor 115 within the predetermined time from the detection of the above-mentioned medication / non-medication.
  • the liquid medicine 1 contained in the container 3 is removed by eye drops. “2” is assigned as the decreased value.
  • FIG. 10 is a diagram illustrating a data configuration example of the schedule table 224 of the present embodiment.
  • the schedule table 224 is obtained from a terminal of a person who can be a subject of medication management, such as the medical institution terminal 300, the dispensing pharmacy terminal 500, or the family terminal 600, or a predetermined terminal (eg, a smartphone or a PC) operated by the medication person himself. It is the table which stored the information of the medication schedule which was input.
  • the data structure is based on the user ID that uniquely identifies the drug taker as a key, the device ID of the drug management device 100 provided in the container 3 used by the drug taker, the drug ID of the drug to be administered, the drug management It is a set of records composed of data such as information such as notification date and time of alert output and notification date and time of next prescription.
  • FIG. 11 is a diagram showing a data configuration example of the medication status table 225 of the present embodiment.
  • the medication status table 225 is a table in which values obtained by the server 200 obtaining detection results (each record of the detection result table 125) from each medication management apparatus 100 and appropriately processing them are stored.
  • the data structure is based on the device ID that uniquely identifies the medication management device 100 as a key, and the user ID, drug ID, drug initial registration date, instillation date (latest), number of instillations (total), and remaining drug (%). , And an instruction flag.
  • each data of device ID, user ID, medicine ID, and medicine first registration date and time is an eigenvalue which each medication management device 100 holds in the storage device 101 as described with reference to FIG.
  • the medication management apparatus 100 transmits the contents of the detection result table 125 to the server 200, it is transmitted together.
  • the instillation date and time (latest) is the value of the “detection date and time” of the detection result most recently obtained from the medication management apparatus 100.
  • the number of instillations (total) is “1” for “medicine / non-medication” among detection results common to the set of user ID, drug ID, and drug initial registration date and time obtained from the medication management apparatus 100.
  • the total value of the “passing” values in the records in which the values of “rotation” and “pressing” are 1 or more That is, it is a value obtained by calculating the total value of the number of instillations for a predetermined patient who has started taking an eye drop from a certain date and time. Therefore, each time the server 200 obtains a detection result having a “pass” value of 1 or more from the medication management apparatus 100, the value of the number of instillations (total) increases.
  • the remaining amount (%) of the medicine is calculated by the server 200 based on the above-mentioned value of the number of eye drops (total) and each value of the capacity of the medicine and the pace of medication in the medicine information table 226 described later. It is the value which shows the ratio which eye drop residual amount tightens among the capacity
  • this method of calculating the remaining amount of medicine is merely an example, and other methods may be adopted.
  • the instruction flag is determined by the server 200 based on the values of the instilled date and time (latest) and the remaining amount of medicine (%) and the medicine information table 226 and the content of the medicine guidance. This is the flag that was given.
  • the server 200 indicates “scheduled arrival”. Set the flag. Further, when the obtained time goes back more than a predetermined reference time from the current time, the server 200 sets a “delay” flag. In addition, when the value of the instillation date (latest) has not been set, that is, when no instillation has been performed, the server 200 adds the time value of the medication pace of the medicine to the value of the medicine first registration date and time. If the time obtained in this way is the future within a predetermined time from the current time, a “schedule arrival” flag is set. Further, when the obtained time goes back more than a predetermined reference time from the current time, the server 200 sets a “delay” flag.
  • the server 200 sets a “replenishment required” flag. It should be noted that processing such as calculation of the amount of remaining medicine (%) and comparison with a predetermined standard accompanying setting of the “replenishment required” flag may be executed not by the server 200 but by the medication management apparatus 100. In that case, the medication management apparatus 100 determines whether the liquid level position of the liquid medicine 1 detected by the liquid level sensor 115 is below a predetermined lower limit value, and if the liquid level position falls below the lower limit value, The amount is specified to be below a predetermined standard. Then, the medication management device 100 outputs warning information to its own output device 105. As this warning information, for example, a message urging drug replenishment can be assumed, but various forms such as lamp emission of a predetermined color (other forms of the output device 105) can be adopted, and are not limited.
  • this warning information for example, a message urging drug replenishment can be assumed, but various forms such as lamp emission of a predetermined color (other forms of the output device 105) can be adopted,
  • FIG. 12 is a diagram showing a data configuration example of the medicine information table 226 of the present embodiment.
  • the medicine information table 226 is a table that stores information on the container 3 used for taking each medicine and information on an appropriate medication pace.
  • the data structure is a record composed of data such as the capacity of the container 3 used for taking the medicine (that is, the amount of medicine 1 that can be accommodated) and the medication pace of the medicine, using the medicine ID that uniquely identifies the medicine as a key.
  • the medication pace is a value defined by an appropriate organization such as a medical institution regarding the drug, and is a value defining the amount of medication per medication and the time interval of the medication. For example, a value of “1 time (1 ml) / 3 hours” indicates that the drug is taken once every 3 hours and the dose is 1 ml.
  • FIG. 13 is a diagram illustrating a data configuration example of the notification information table 227 of the present embodiment.
  • the notification information table 227 is a table that stores the content of the medication instruction given to the medication recipient.
  • the data structure is that the device ID of the medication management apparatus 100 (the device ID of the container 3 used by the medication recipient who is the subject of medication instruction) is used as a key, the user ID of the medication recipient, the medicine of the medication to be taken. It is a collection of records consisting of data such as ID, medication instruction content (latest), and instruction date.
  • the value of the medication instruction content is a value set by the server 200 based on the above-described instruction flag in the medication status table 225 and a text indicating the corresponding instruction content (held in the storage device 201 in advance).
  • the medical institution terminal 300, the pharmaceutical company terminal 400, and the dispensing pharmacy terminal 500 generates the medication instruction content based on each record of the medication status table 225 described above and sends it to the corresponding medication recipient. It may be transmitted to the server 200.
  • FIG. 14 is a diagram showing a flow example of a medication management method in the present embodiment.
  • the medical institution terminal 300 of the medical institution that prescribes the drug to the patient
  • the dispensing pharmacy terminal 500 of the dispensing pharmacy that dispensed according to the prescription
  • the pharmaceutical company terminal 400 of the company transmits in advance a registration request including the user ID of the patient who is the prescription partner and the device ID of the medication management apparatus 100 provided in the container of each prescription or sold medicine to the server 200.
  • the server 200 generates a record including the user ID and the device ID (at least one) and registers it in the medication status table 225.
  • the terminal of a person who can be a subject of medication management such as the medical institution terminal 300, the dispensing pharmacy terminal 500, or the family terminal 600, or a predetermined terminal (eg, a smartphone or a PC) operated by the medication person himself / herself is a medication schedule.
  • the server 200 shall transmit the input screen 1000 shown in FIG. 14 with respect to these terminals, and will acquire the information of a medication schedule via this input screen 1000.
  • the server 200 registers the medication schedule information thus obtained in the schedule table 224 in association with the user ID of the medication user.
  • the server 200 detects the arrival of the notification date and time of the alert output related to each patient's medication based on the information in the schedule table 224, and can specify the medication management device 100 (user ID as a key) of the subject medication. It is assumed that an alert output prompting medication is transmitted to the device ID).
  • the server 200 transmits information on the next prescription date and time of the medicine taken by the drug taker based on the information of “notification date and time of next prescription” in the schedule table 224 in addition to the alert output that prompts the patient to take the medicine. You may do that.
  • the medication management apparatus 100 of each medication person reads the detection result by the sensor 110 in a predetermined period from the detection result table 125 and transmits it to the server 200 via the network 20 (s100).
  • the contents of the detection results transmitted from each medication management apparatus 100 to the server 200 are as described above.
  • the server 200 is connected to the server 200 via another communication device that can be connected to the network 20 (for example, a smartphone held by the medication user). It may be transmitted.
  • the communication method and communication method are not limited.
  • the server 200 receives the detection result transmitted as described above from each medication management apparatus 100 (s101). Further, the server 200 searches for an existing record in the medication status table 225 using at least one of the device ID and the user ID indicated by the received detection result as a key (s102), and the detection is performed on the corresponding record. Each value (eg: medication / non-medication, passage, rotation, press, liquid level) of the medicine ID, the medicine first registration date and the medicine operation included in the result is set in association with each other (s103).
  • Each value eg: medication / non-medication, passage, rotation, press, liquid level
  • the server 200 executes the above-described instillation date and time (latest), the number of instillations (total), the remaining amount of medicine (%), and the identification of the guidance flag based on the information obtained up to step s103 (s104). ), The obtained values are linked to form a medication history and stored in the corresponding record of the medication status table 225 (s105). The calculation of each value and the specific processing of the guidance flag are as described above.
  • the server 200 receives a predetermined request from any one of the medical institution terminal 300, the pharmaceutical company terminal 400, and the dispensing pharmacy terminal 500, and for example, a guidance flag is given among the records of the medication status table 225. Is specified (s106).
  • the server 200 specifies text indicating the corresponding instruction content (preliminarily stored in the storage device 201) based on the instruction flag obtained in step s106 described above, and the instruction content is stored in the corresponding medication administration device 100 of the corresponding drug taker. Alternatively, it is delivered to a predetermined device (for example, a medication person's smartphone whose address on the network such as an e-mail address is already known to the server 200) (s107).
  • a predetermined device for example, a medication person's smartphone whose address on the network such as an e-mail address is already known to the server 200
  • the medication management device 100 or the like receives the information on the content of the medication instruction and displays it on the output device 105 or the like (FIG. 16: screen 1200) (s108).
  • the drug taker browses this screen 1200 and understands that his / her medication should be improved not in accordance with the instructions of the doctor, etc., and that the container 3 needs to be refilled. You can be fully aware of what you are doing.
  • server 200 may also distribute the medication history regarding the drug of the drug taker along with the content of the medication instruction.
  • the sensor may detect a predetermined operation in an opening / closing structure of a predetermined opening of the container.
  • opening and closing of a door in a storage case of a medicine eg, solid medicine or packaged in a solid package
  • a discharge container eg: liquid medicine or granular medicine
  • a medicine eg: liquid medicine or granular medicine
  • a medication management server or the like it is possible to manage a medication history with good accuracy according to the medication operation and to support prompt and accurate medication guidance.
  • the sensor may further include a sensor that detects a passing event near the predetermined opening when the medicine in the container moves from the predetermined opening to the outside of the container. .
  • the senor detects at least one of rotation of the container and pressing against a predetermined location for moving the medicine in the container from the predetermined opening to the outside of the container. It may be further included.
  • the senor may further include a sensor that detects a drug surface position in the container.
  • the medication management apparatus further includes an interface for accepting an indication of intention of medication or non-medicine at a medication person upon detection of a predetermined operation in the opening / closing structure, and the communication device includes the interface
  • the information on the intention display received in step 1 may be transmitted to the external device in association with the detection result.
  • the sensor detects a passing event near the predetermined opening when the medicine in the container moves from the predetermined opening to the outside of the container, or the medicine in the container
  • the remaining amount of the medicine in the container is calculated based on either the passing event detected by the sensor or the surface position of the medicine, and the calculated remaining amount of medicine is a predetermined standard. If the value is lower than the value, an arithmetic device that outputs warning information to a predetermined device may be further provided.
  • the medication management apparatus of the present embodiment may further include an arithmetic device that receives predetermined medication guidance information based on the transmitted detection result from the external device and outputs the medication guidance information to an output device.
  • the server receives predetermined medication guidance information based on the medication history from the terminal from the terminal that has delivered the medication history, and the medication guidance information is received from the terminal. It is good also as what transmits to the said medication person's medication management apparatus which information shows.
  • the server receives the detection result, associates each identification information of the medication subject to be managed and the medicine indicated by the detection result, and each value of the medication operation,
  • the medication history is stored in a storage device as a medication history, in response to a request from any terminal of a medical institution, a pharmaceutical company, or a dispensing pharmacy, or at every elapse of a predetermined period, at least the request of the terminal It may be distributed to the terminal that has performed.

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Abstract

[Problème] Gérer un historique d'administration de médicament précis correspondant à une opération d'administration de médicament, et faciliter un guidage d'administration de médicament rapide et précis. [Solution] La présente invention concerne un appareil de gestion d'administration de médicament 100, l'appareil de gestion d'admiration de médicament 100 étant configuré de façon à être pourvu d'un capteur 110 pour détecter une ou une pluralité d'opérations d'administration de médicament par une personne prenant un médicament depuis un récipient 3 d'un médicament 3, et un appareil de communication 106 pour transmettre le résultat de détection par le capteur 110 à un serveur 200 par l'intermédiaire d'un réseau prédéterminé 20.
PCT/JP2017/003543 2016-02-04 2017-02-01 Appareil de gestion d'administration de médicament, procédé de gestion d'administration de médicament, et système de gestion d'administration de médicament WO2017135279A1 (fr)

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JP2016019450A JP2019076119A (ja) 2016-02-04 2016-02-04 服薬管理装置、服薬管理方法、および服薬管理システム

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JP7413816B2 (ja) * 2020-02-14 2024-01-16 ニプロ株式会社 服薬管理システム
JP7324265B2 (ja) * 2021-11-19 2023-08-09 株式会社日立システムズ 服薬管理システム、服薬管理方法、及び薬収容ケース

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JPH0329661A (ja) * 1989-06-28 1991-02-07 Toshiko Takahashi 薬容器
JP2009042935A (ja) * 2007-08-07 2009-02-26 Tosho Inc 調剤システム及び処方箋受付装置
US20140257206A1 (en) * 2012-10-23 2014-09-11 Rxense, Inc. Portable management and monitoring system for eye drop medication regiment
JP2014194716A (ja) * 2013-03-29 2014-10-09 Nakayo Inc 服薬管理機能を有する通信装置
JP2015024040A (ja) * 2013-07-26 2015-02-05 株式会社リコー 薬服用支援システム及び薬箱
JP2015516823A (ja) * 2012-02-26 2015-06-18 アドヒアテック インコーポレイティド 容器の内容物、所在場所および周囲環境を判定するためのシステムおよび方法
JP2015228080A (ja) * 2014-05-30 2015-12-17 日本電信電話株式会社 服薬管理支援システム及び服薬管理支援方法

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Publication number Priority date Publication date Assignee Title
JPH0329661A (ja) * 1989-06-28 1991-02-07 Toshiko Takahashi 薬容器
JP2009042935A (ja) * 2007-08-07 2009-02-26 Tosho Inc 調剤システム及び処方箋受付装置
JP2015516823A (ja) * 2012-02-26 2015-06-18 アドヒアテック インコーポレイティド 容器の内容物、所在場所および周囲環境を判定するためのシステムおよび方法
US20140257206A1 (en) * 2012-10-23 2014-09-11 Rxense, Inc. Portable management and monitoring system for eye drop medication regiment
JP2014194716A (ja) * 2013-03-29 2014-10-09 Nakayo Inc 服薬管理機能を有する通信装置
JP2015024040A (ja) * 2013-07-26 2015-02-05 株式会社リコー 薬服用支援システム及び薬箱
JP2015228080A (ja) * 2014-05-30 2015-12-17 日本電信電話株式会社 服薬管理支援システム及び服薬管理支援方法

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