WO2017122687A1 - Blood-sucking-arthropod control method and blood-sucking-arthropod control composition for treating elements that form living spaces - Google Patents

Blood-sucking-arthropod control method and blood-sucking-arthropod control composition for treating elements that form living spaces Download PDF

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Publication number
WO2017122687A1
WO2017122687A1 PCT/JP2017/000655 JP2017000655W WO2017122687A1 WO 2017122687 A1 WO2017122687 A1 WO 2017122687A1 JP 2017000655 W JP2017000655 W JP 2017000655W WO 2017122687 A1 WO2017122687 A1 WO 2017122687A1
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Prior art keywords
blood
sucking
arthropod control
living space
sucking arthropod
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PCT/JP2017/000655
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French (fr)
Japanese (ja)
Inventor
英則 大同
あゆみ 川瀬
新葉 笹倉
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三井化学アグロ株式会社
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Application filed by 三井化学アグロ株式会社 filed Critical 三井化学アグロ株式会社
Priority to BR112018014039-2A priority Critical patent/BR112018014039B1/en
Publication of WO2017122687A1 publication Critical patent/WO2017122687A1/en
Priority to PH12018550106A priority patent/PH12018550106A1/en

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    • A—HUMAN NECESSITIES
    • A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01M—CATCHING, TRAPPING OR SCARING OF ANIMALS; APPARATUS FOR THE DESTRUCTION OF NOXIOUS ANIMALS OR NOXIOUS PLANTS
    • A01M1/00—Stationary means for catching or killing insects
    • A01M1/20—Poisoning, narcotising, or burning insects
    • A—HUMAN NECESSITIES
    • A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
    • A01N31/00—Biocides, pest repellants or attractants, or plant growth regulators containing organic oxygen or sulfur compounds
    • A01N31/08—Oxygen or sulfur directly attached to an aromatic ring system
    • A01N31/14—Ethers
    • A—HUMAN NECESSITIES
    • A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
    • A01N37/00—Biocides, pest repellants or attractants, or plant growth regulators containing organic compounds containing a carbon atom having three bonds to hetero atoms with at the most two bonds to halogen, e.g. carboxylic acids
    • A01N37/44—Biocides, pest repellants or attractants, or plant growth regulators containing organic compounds containing a carbon atom having three bonds to hetero atoms with at the most two bonds to halogen, e.g. carboxylic acids containing at least one carboxylic group or a thio analogue, or a derivative thereof, and a nitrogen atom attached to the same carbon skeleton by a single or double bond, this nitrogen atom not being a member of a derivative or of a thio analogue of a carboxylic group, e.g. amino-carboxylic acids
    • A01N37/46—N-acyl derivatives

Definitions

  • the present invention relates to a blood-sucking arthropod control method and a blood-sucking arthropod control composition for treating living space formations for preventing the spread of infections mediated by blood-sucking arthropods.
  • Pest control methods to control these disease-borne pests include spraying an insecticide containing a pest control ingredient, applying a contact insecticide on the surface of an indoor wall, immersing the insecticide in a mosquito net, etc. Has been used.
  • Known pest control components include pyrethroid compounds and neonicotinoid compounds.
  • Patent Document 1 International Publication No. 2005/21488
  • Patent Document 2 International Publication No. 2005/73165
  • Patent Document 3 International Publication No. 2006/137376
  • Patent Document 4 International Publication No. 2006/137395
  • Patent Document 5 International Publication No. 2010/013567 Pamphlet
  • Patent Documents 1 to 5 describe that it is possible to control disease-borne pests, details of specific effective concentrations and methods of use are not disclosed, and the above amide derivatives are used. The method for controlling pests has not been substantially disclosed.
  • one embodiment of the present invention provides a blood-sucking arthropod control method and a blood-sucking arthropod control composition for treating living space formation, which are excellent in durability and effective against resistant pests. Is an issue.
  • the present inventors have formed residential spaces such as house walls and mosquito nets with a composition containing an amide derivative represented by the general formula (1) as an active ingredient.
  • the present inventors have found that pest control is possible for a long period of time and is effective against resistant pests.
  • One embodiment of the present invention is as follows.
  • Q represents a phenyl group or a phenyl group substituted with a fluorine atom.
  • R represents a hydrogen atom or a methyl group.
  • Y 1 and Y 2 are each independently a bromine atom, an iodine atom or a trifluoromethyl group.
  • the amide derivative represented by the general formula (1) is 2-fluoro-3- (N-methylbenzamide) -N- (2-bromo-6-trifluoromethyl-4- (heptafluoropropane-).
  • ⁇ 3> The blood-sucking arthropod control method according to ⁇ 1> or ⁇ 2>, wherein the living space formation is a house wall surface or a mosquito net.
  • ⁇ 4> The method for controlling blood-sucking arthropods according to any one of ⁇ 1> to ⁇ 3>, wherein the method for treating the living space formation is spraying or dipping treatment.
  • the blood-sucking arthropod to be controlled is at least one selected from the group consisting of Anopheles insects, Aedes genus insects and Culex genus insects which are Diptera mosquitoes (Clicidae), ⁇
  • the method for controlling blood-sucking arthropods according to any one of 1> to ⁇ 4>.
  • ⁇ 6> The blood-sucking arthropod control method according to ⁇ 5>, wherein the Dipteridae (Clicidae) insect is an Anopheles genus insect.
  • the blood-sucking arthropod control composition for treating living space formations contains, as a further active ingredient, at least one compound selected from the group consisting of permethrin, alpha cypermethrin, deltamethrin, and etofenprox.
  • the blood-sucking arthropod control method according to any one of ⁇ 1> to ⁇ 7>.
  • the blood-sucking arthropod control method according to any one of ⁇ 1> to ⁇ 8>, wherein the blood-sucking arthropod control composition for treating living space formations is a wettable powder or a flowable agent. .
  • a blood-sucking arthropod control composition for treating living space formations which contains at least one amide derivative represented by the formula:
  • the amide derivative represented by the general formula (1) is 2-fluoro-3- (N-methylbenzamide) -N- (2-bromo-6-trifluoromethyl-4- (heptafluoropropane-).
  • the blood-sucking arthropod control composition for living space formation treatment according to ⁇ 12> or ⁇ 13>, which is used for treatment of a house wall or a mosquito net as a living space formation.
  • ⁇ 15> Used for control of at least one species selected from the group consisting of Anopheles insects, Aedes insects, and Culex insects, which are Fliesidae (Diptera) as a blood-sucking arthropod, ⁇ The blood-sucking arthropod control composition for treating living space formations according to any one of 12> to ⁇ 14>.
  • the blood-sucking arthropod control composition for treating living space formations according to ⁇ 15>, wherein the Dipteridae (Clicidae) insect is an Anopheles insect.
  • ⁇ 17> The blood-sucking arthropod control for treating living space formations according to ⁇ 15> or ⁇ 16>, wherein the Anopheles genus insect is at least one of Gambier gambiae and Anopheles sinensis Composition.
  • the blood-sucking arthropod control composition for living space formation treatment according to any one of ⁇ 12> to ⁇ 18>, which is a wettable powder or a flowable agent.
  • a method for controlling blood-sucking arthropods and a composition for controlling blood-sucking arthropods for treating living space formation which are excellent in durability and effective against resistant pests. be able to.
  • a blood-sucking arthropod control composition for treating living space formation according to an embodiment of the present invention is at least an amide derivative represented by the following general formula (1): Contains one as an active ingredient.
  • the blood-sucking arthropod control method according to one embodiment of the present invention includes a blood-sucking node for treating living space formations, which contains at least one amide derivative represented by the following general formula (1) as an active ingredient.
  • the living space formation is treated with the paw animal control composition.
  • the blood-sucking arthropod control method according to the present embodiment is also excellent in sustainability and effective against resistant pests, and exhibits a high pest control effect.
  • Q represents a phenyl group or a phenyl group substituted with a fluorine atom.
  • R represents a hydrogen atom or a methyl group.
  • Y 1 and Y 2 each independently represents a bromine atom, an iodine atom or a trifluoromethyl group.
  • the amide derivative represented by the general formula (1) used in the present embodiment may contain one or more asymmetric carbon atoms or asymmetric centers in the structural formula, and two or more kinds of optical derivatives may be used. Although isomers may exist, all of the optical isomers and a mixture in which they are contained in an arbitrary ratio are also included.
  • the amide derivative represented by the general formula (1) used in the present embodiment may have two or more geometric isomers derived from a carbon-carbon double bond in the structural formula. And all geometric isomers and mixtures in which they are contained in any proportion.
  • the compound represented by the general formula (1) is 2-fluoro-3- (N-methylbenzamide) -N- (2-bromo-6-trifluoromethyl-4-methyl represented by the following formula (2). (Heptafluoropropan-2-yl) phenyl) benzamide is preferred.
  • the amide derivative represented by the general formula (1) used in the present embodiment can be produced, for example, according to the method described in the specification of International Publication No. 2010/013567.
  • blood-sucking arthropod that can be controlled by the composition and the method for controlling a blood-sucking arthropod according to the present embodiment include the following blood-sucking arthropods. It is not limited.
  • Anopheles genus As a Diptera (Clicidae) insect, Anopheles genus, Anopheles gambiae, Anopheles arabiensis, Anopheles funestus, Anopheles melas, Anopheles minimus, Anopheles dibes, Anopheles staphines Culex pipiens molestus, Culex pipiens pipiens, Culex quinquefasciatus, Culex pipiens pallens, Culex restus, Culex tarsitalis, Culex tarsalis Aedes genus, Aedes aegypti, Aedes albopictus, Aedes Japanicus, Aedes vexans, etc.
  • insects such as abs, flies, flyfish, sand flies, nucifers, tsetse flies, chironomids, fleas, lices, bed bugs, sand turtles, ticks, ticks.
  • the blood-sucking arthropod is a fly order mosquito insect from the viewpoint of controlling effect.
  • the amide derivative represented by the general formula (1) in the present embodiment is usually mixed with a suitable solid carrier or liquid carrier, and further, a surfactant, a penetrating agent, a spreading agent, a thickening agent if desired.
  • a surfactant emulsion (emulsifiable concentrate), Wettable powder, flowable, water-soluble powder, water dispersible granule, water-soluble granule, suspension concentrate, milk Any dosage form such as concentrated emulsion, suspoemulsion, microemulsion, dustable powder, granule tablet, emulsifiable gel
  • Rukoto can.
  • the preparations of any of the above dosage forms can be provided by being enclosed in a water-soluble package such as a water-soluble capsule or a water-soluble film bag.
  • a water-soluble package such as a water-soluble capsule or a water-soluble film bag.
  • the composition according to the present embodiment may be a wettable powder or a flowable agent.
  • the inert carrier that can be used in the composition according to this embodiment may be a solid or a liquid.
  • Examples of materials that can be used as a solid inert carrier include soybean powder, cereal powder, wood powder, bark powder, saw powder, tobacco stem powder, walnut shell powder, bran, fiber powder, residue after extraction of plant extracts, Synthetic polymers such as pulverized synthetic resins, clays (eg kaolin, bentonite, acid clay), talc (eg talc, pyrophyllide, etc.), silicas (eg diatomaceous earth, silica sand, mica, white carbon (hydrous finely divided silicon, hydrous) Synthetic high-dispersion silicic acid, also called silicic acid, may contain calcium silicate as the main component depending on the product.]), Activated carbon, sulfur powder, pumice, calcined diatomaceous earth, brick ground (eg clay), fly ash, sand, calcium carbonate , Inorganic mineral powders such as calcium phosphate, chemical fertilizers such as ammonium sulfate, phosphoric acid, ammonium nitrate
  • the active ingredient compound can be dispersed with the aid of an auxiliary agent (for example, a surfactant) in addition to those having a solvent ability per se, and having no solvent ability.
  • an auxiliary agent for example, a surfactant
  • water alcohols (eg, methanol, ethanol, isopropanol, butanol, ethylene glycol, etc.), ketones (eg, acetone, methyl ethyl ketone, methyl isobutyl ketone, diisobutyl ketone, cyclohexanone, etc.), ethers (eg, Diethyl ether, dioxane, cellosolve, diisopropyl ether, tetrahydrofuran, etc.), aliphatic hydrocarbons (eg kerosene, mineral oil, etc.), aromatic hydrocarbons (eg benzene, toluene, xylene, solvent naphtha, alkylnaphthalen
  • solid carriers and liquid carriers may be used alone or in combination of two or more.
  • surfactant examples include polyoxyethylene (mono or di) alkyl ether, polyoxyethylene alkyl (mono or di) phenyl ether, polyoxyethylene (mono, di or tri) styryl phenyl ether, polyoxyethylene polyoxypropylene Block copolymer, polyoxyethylene fatty acid (mono or di) ester, sorbitan fatty acid ester, polyoxyethylene sorbitan fatty acid ester, castor oil ethylene oxide adduct, acetylene glycol, acetylene alcohol, ethylene oxide adduct of acetylene glycol, ethylene of acetylene alcohol
  • Nonionic surfactants such as oxide adducts and alkyl glycosides, alkyl sulfate esters, alkylbenzene sulfonates, ligni Sulfonate, alkylsulfosuccinate, dialkylsulfosuccinate, naphthalenesulf
  • the content of these surfactants is not particularly limited, but is usually in the range of 0.05 to 20 parts by weight per 100 parts by weight of the preparation. These surfactants may be used alone or in combination of two or more.
  • thickeners examples include natural gums such as xanthan gum, welan gum, guar gum, tragacanth gum, and gum arabic; fine powders of inorganic minerals such as smectite, sepiolite, attapulgite, laponite, montmorillonite, hectorite; carboxymethylcellulose, hydroxyethylcellulose, carboxy Cellulose derivatives such as ethyl cellulose, methyl cellulose, hydroxypropyl cellulose and salts thereof; starch derivatives such as various grades of dextrin and sodium carboxymethyl starch; natural products such as sodium alginate and sodium caseinate and derivatives thereof; polyvinyl alcohol, polyacryl Examples thereof include acids and derivatives thereof, and water-soluble synthetic polymers such as polyvinylpyrrolidone. Moreover, these thickeners may be used independently or may use 2 or more types together.
  • the protective colloid agent examples include water-soluble celluloses such as methylcellulose, hydroxyethylcellulose, hydroxypropylcellulose, hydroxypropylmethylcellulose and carboxymethylcellulose, polyalkylene glycols such as polyethylene glycol and polypropylene glycol, polyvinyl alcohol, polyvinyl pyrrolidone, guar gum and gum arabic. , Gelatin, polyacrylate, alginate and the like. Moreover, these protective colloid agents may be used alone or in combination of two or more.
  • antifreezing agent examples include ethylene glycol, diethylene glycol, propylene glycol, glycerin and the like. These antifreeze agents may be used alone or in combination of two or more.
  • antifoaming agents examples include silicone, acetylene glycol, fluorine, and fatty acid. These antifoaming agents may be used alone or in combination of two or more.
  • antifungal agent examples include benzothiazole derivatives, sorbic acid, potassium sorbate, butyl p-oxybenzoate, and the like. These antifungal agents may be used alone or in combination of two or more.
  • the composition according to this embodiment further includes at least one of other generally known insecticidal components (insect controlling components) and synergists.
  • insecticidal ingredients include, for example: Acrinathrin, permethrin, phenothrin, d-phenothrin, allethrin, dd-alleslin, dd-alleslin, pyrethrin, praretrin, ciphenothrin, cyfluthrin, beta-cyfluthrin, bifenthrin, cycloprotorin, cyhalothrin, lambda cihalothrin, gamma cyhalothrin , Cypermethrin, sigmacipermethrin, alpha cypermethrin, zetacypermethrin, dimefluthrin,
  • composition according to the present embodiment tends to be more excellent in insecticidal effect on blood-sucking arthropods, and therefore, as other insecticidal components, at least selected from the group consisting of permethrin, alpha cypermethrin, deltamethrin and etofenprox.
  • insecticidal components at least selected from the group consisting of permethrin, alpha cypermethrin, deltamethrin and etofenprox.
  • one kind of compound may be further contained as an active ingredient.
  • the weight ratio of the amide derivative represented by the general formula (1) to the total of other insecticidal components and synergists is such that the other pesticidal components are contained in 1 part by weight of the amide derivative represented by the general formula (1).
  • the amount is usually 0.01 to 100 parts by weight, preferably 0.02 to 50 parts by weight.
  • the amount of the active ingredient of the composition according to this embodiment is usually 0.1 to 20% by weight for powders, 5 to 50% by weight for emulsions, 3 to 90% by weight for wettable powders, and 0.1 to 20 for granules. It is preferably 5% by weight, 5% to 90% by weight for flowable preparations, and 3% to 90% by weight for wettable granules.
  • the amount of carrier in each dosage form is usually 60 to 99.9% by weight for powders, 40 to 95% by weight for emulsions, 10 to 90% by weight for wettable powders, and 80 to 99.9% by weight for granules.
  • the flowable preparation is preferably 10 to 95% by weight, and the granular wettable powder is preferably 10 to 90% by weight.
  • the amount of the adjuvant is usually 0.1 to 20% by weight for powders, 1 to 20% by weight for emulsions, 0.1 to 20% by weight for wettable powders, 0.1 to 20% by weight for granules, It is preferably 0.1 to 20% by weight for flowable preparations and 0.1 to 20% by weight for granular wettable powders.
  • the composition according to the present embodiment may be used as it is, or may be used by diluting or suspending it appropriately with water or the like.
  • the amount of the active ingredient is usually preferably used at a concentration of 0.0001 to 5000 ppm, more preferably 0.01 to 1000 ppm.
  • the living space is a space into which at least one of humans and livestock enters
  • examples of the living space formation include a house wall surface, a ceiling, a pillar, a column, a window, a door, a tent, and a mosquito net.
  • the house wall surface of a house When the wall surface of a house is treated with the composition according to the present embodiment, the house wall surface may be treated such as spraying, coating, and transpiration. Moreover, using the material spread
  • the material of the house wall is concrete (cement), brick, bamboo, wood, tile, ceramic, mud, etc.
  • the material of the ceiling is thatch, tin, concrete (cement), bamboo, wood, etc. The present invention is not limited to these examples.
  • the mosquito net When treating a mosquito net with the composition according to the present embodiment, the mosquito net may be immersed in the composition according to the present embodiment, or a solution or suspension in which the composition according to the present embodiment is appropriately diluted with water or the like. The mosquito net may be soaked in the chemical solution thus applied, and other treatments such as spraying and coating may be applied to the mosquito net.
  • Examples of the material of the mosquito net include resin, natural fiber, fiber material such as glass fiber, and the like, and among them, resin is preferable.
  • examples of natural fibers include pulp, cellulose, cotton, hemp, and hair.
  • a thermoplastic resin is preferable.
  • examples of the thermoplastic resin include polyolefin resin, polyvinyl alcohol, polyvinyl acetate, polycarbonate, polyester, polyamide (for example, nylon), polystyrene, polymethyl methacrylate, acrylonitrile-butadiene-styrene copolymer, and polyvinyl chloride. Can be mentioned.
  • polyolefin resin is preferable.
  • polystyrene resin the compounds listed in the following (i) to (iii) are preferable.
  • ⁇ -olefin homopolymer polyethylene, polypropylene, etc.
  • ethylene- ⁇ -olefin copolymer for example, ethylene-propylene copolymer, ethylene-1-butene copolymer, ethylene-4-methyl-1-pentene copolymer, or ethylene-hexene copolymer Such.
  • (Iii) Copolymer of an organic carboxylic acid derivative having an ethylenically unsaturated bond and ethylene: for example, ethylene-methyl methacrylate copolymer, ethylene-vinyl acetate copolymer, ethylene-acrylic acid copolymer, ethylene- Vinyl acetate-methyl methacrylate copolymer.
  • the amount of the active ingredient carried on the surface of the living space formation may be appropriately adjusted according to the application time, application place, treatment method, etc., and is preferably 0.1 to 3000 mg / m 2 , for example. More preferably, it is 1 to 500 mg / m 2 .
  • the composition according to the present embodiment is for living space formation treatment, but is a blood-sucking arthropod, for example, a lake, a wetland, a paddy field, a reservoir, a septic tank, a drainage channel, etc. It can be expected to prevent infections such as malaria, dengue fever and zika fever prophylactically.
  • composition according to the present embodiment may be used by mixing with various other insecticides, acaricides, nematicides, bactericides, synergists and the like as needed during processing.
  • a brofuranilide slurry, a thickener solution A, and a thickener solution B were prepared.
  • ⁇ Preparation Example 1> Compound represented by formula (2) (2-fluoro-3- (N-methylbenzamide) -N- (2-bromo-6-trifluoromethyl-4- (heptafluoropropan-2-yl) phenyl) benzamide ) 50.0 parts, 2.0 parts of polyoxyethylene styrylated phenol phosphate salt, 1.0 part of dioctyl sulfosuccinate, 0.1 part of silicone antifoaming agent and 46.9 parts of water were mixed uniformly.
  • Example 1 ⁇ Formulation example 1> 50.0 parts of the compound represented by the formula (2), 2.5 parts of diethylene glycol monododecyl ether (polyoxyethylene monoalkyl ether), 2.5 parts of nonaethylene glycol monododecyl ether (polyoxyethylene monoalkyl ether), Polyvinyl alcohol (2.0 parts), kaolin (38.0 parts), white carbon (5.0 parts) were uniformly ground and mixed to obtain a wettable powder.
  • diethylene glycol monododecyl ether polyoxyethylene monoalkyl ether
  • nonaethylene glycol monododecyl ether polyoxyethylene monoalkyl ether
  • Polyvinyl alcohol 2.0 parts
  • kaolin 38.0 parts
  • white carbon 5.0 parts
  • Example 2 ⁇ Formulation example 2> 50.0 parts of the compound represented by the formula (2), 3.0 parts of alkyl sulfate ester salt, 4.0 parts of dialkyl sulfosuccinate, 3.0 parts of polyoxyethylene monoalkyl ether, 2.0 parts of polyvinyl alcohol, 38.0 parts of kaolin and the above were ground and mixed uniformly to obtain a wettable powder.
  • Example 3 ⁇ Formulation example 3> 2. 50.0 parts of the compound represented by the formula (2), 4.0 parts of dialkylsulfosuccinate, 3.0 parts of polyoxyethylene alkyl ether, salt of formalin condensate (formaldehyde condensate) of alkylnaphthalenesulfonic acid 0 parts, 39.5 parts of kaolin, 0.5 parts of a silicone-based antifoaming agent, and the above were ground and mixed uniformly to obtain a wettable powder.
  • Example 4 ⁇ Formulation example 4> 50.0 parts of the compound represented by formula (2), 5.0 parts of alkylnaphthalene sulfonate, 3.0 parts of lignin sulfonate, 36.5 parts of kaolin, 5.0 parts of white carbon, silicone-based defoaming 0.5 parts of the agent was uniformly ground and mixed to obtain a wettable powder.
  • Example 5 ⁇ Formulation example 5> 50.0 parts of the compound represented by the formula (2), 1.8 parts of polyoxyethylene tristyryl phenyl ether ammonium sulfate (ethylene oxide addition mole number 14), 1.2 parts of polyoxyethylene polyoxypropylene block copolymer, propylene A flowable agent was obtained by uniformly mixing 5.0 parts of glycol, 0.5 parts of a silicone-based antifoaming agent, 0.1 part of bentonite and 41.4 parts of water and wet pulverizing them.
  • Example 6 ⁇ Formulation example 6> 10.0 parts of brofuranilide slurry obtained in Preparation Example 1, 3.0 parts of polyoxyethylene tristyryl phenyl ether ammonium sulfate (ethylene oxide addition mol number 14), formalin condensate (formaldehyde condensate) of alkylnaphthalene sulfonic acid A flowable agent was obtained by uniformly mixing 5.0 parts of the above salt, 60.0 parts of the thickener solution A obtained in Preparation Example 2, and 22.0 parts of water.
  • Example 7 ⁇ Formulation example 7> Example 6 In Example 6, except that 5.0 parts of salt of formalin condensate (formaldehyde condensate) of alkylnaphthalenesulfonic acid was changed to 10.0 parts and 22.0 parts of water were changed to 17.0 parts. In the same manner as above, a flowable agent was obtained.
  • Example 8 ⁇ Formulation example 8> In Example 7, except that 3.0 parts of polyoxyethylene tristyrylphenyl ether ammonium sulfate salt (ethylene oxide addition mole number 14) was changed to 5.0 parts, and 17.0 parts of water was changed to 15.0 parts. A flowable agent was obtained in the same manner as in Example 7.
  • Example 9 ⁇ Formulation example 9>
  • Example 6 is the same as Example 6 except that polyoxyethylene tristyryl phenyl ether sulfate ammonium salt (ethylene oxide addition mole number 14) is changed to polyoxyethylene tristyryl phenyl ether ammonium sulfate salt (ethylene oxide addition mole number 9). The flowable agent was obtained.
  • Example 10 ⁇ Formulation Example 10> 40.0 parts of brofuranilide slurry, 3.0 parts of polyoxyethylene tristyryl phenyl ether ammonium sulfate (ethylene oxide addition mole number 14), 5.0 parts of formalin condensate (formaldehyde condensate) of alkylnaphthalene sulfonic acid
  • the flowable agent was obtained by mixing 40.0 parts of the thickener solution B obtained in Preparation Example 3 and 12.0 parts of water.
  • Example 11 ⁇ Formulation Example 11>
  • Example 6 is the same as Example 6 except that polyoxyethylene tristyryl phenyl ether sulfate ammonium salt (ethylene oxide addition mole number 14) is changed to polyoxyethylene tristyryl phenyl ether ammonium sulfate salt (ethylene oxide addition mole number 16). The flowable agent was obtained.
  • compositions and blood-sucking arthropod control method according to the present embodiment will be specifically described in the following test examples, but the present invention is not limited to these.
  • Example 1 Indoor residual spraying (IRS) using various wall materials for Anopheles gambiae Reagent: A wettable powder prepared according to Formulation Example 2 (Example 2), Bendiocarb WP (Reference Example 1) Wall material: Wood, Tile, Cement Test insects: Anopheles gambiae Kisumu system treatment method: In October, a diluted solution of the above formulation is sprayed on the wall surface material with a tower sprayer so as to have a predetermined dose, and then dried at a temperature of 30 ° C. And stored in a constant temperature room with a humidity of 80%.
  • Insecticidal test A standard WHO plastic cone was placed on the treated wall surface material, and a female Gambier anopheles female adult was placed on the lid. After exposure for 3 minutes, Gambier anopheles was placed in a separate container, and after 24 hours, life and death were examined to calculate the mortality. This was continued from November to the following April, and the residual effect was evaluated (three consecutive systems).
  • Insecticidal test A plastic cup was put on the wall material, and a female Chikaieka female was placed inside and covered. After 30 minutes of exposure, Chikaeka was placed in another plastic cup, and after 24 hours, life and death were investigated and the death rate was calculated (two-line system).
  • Test preparation for mosquito net immersion test for Anopheles gambiae flowable agent prepared in accordance with Formulation Example 5 (Example 5), PermaNet2 (Reference Example 3, Deltamethrin)
  • Test insect Anopheles gambiae Kisumu system treatment method: A polyester net was immersed in a diluted solution of the above preparation and dried.
  • Insecticidal test The above-mentioned net is covered with a standard WHO plastic cone, and adult female Gambier spp. Is exposed to 3 minutes or 20 minutes, then placed in another container and knocked down after 1, 24, 48, 72 hours ( The number of KD) was investigated and the KD rate was calculated (triple system).
  • Insecticidal test A standard WHO plastic cone was placed on the treated wall surface material, and a female Gambier anopheles female adult was placed on the lid. After exposure for 3 minutes, Gambier anopheles was placed in a separate container. Further, after 1, 24, 48, and 72 hours, the number of knockdowns (KD) was investigated and the KD rate was calculated (three consecutive systems).
  • Sensitivity test reagent for each strain of Abiepheus gambiae and Aedes aegypti Compound test insect represented by formula (2): Abiepheus gambiae strain , Kisumu RDL line, Akron line, Tiassale 2 line, Aedes aegypti Cayman line, New La line insecticidal test: The compound represented by formula (2) is diluted to a predetermined concentration with acetone, and the target insect is used using a local application device. Applied to adult female breast. After 24 hours, the death rate was investigated.
  • Sensitivity test reagent for Anopheles sinensis Compound represented by formula (2)
  • Test specimen Anopheles sinensis August 2016 Shiga
  • Prefecture collected line insecticide test compound represented by formula (2) was diluted to a predetermined concentration with acetone, and 0.2 ⁇ l / head was applied to the chest of a female target insect using a local application device. After 1, 24, 48 and 72 hours, the number of knockdowns (KD) was investigated and the KD rate was calculated (triple regime).
  • Example 7 Indoor Residual Spraying (IRS) test agent for Anopheles gambiae: wettable powder prepared according to Formulation Example 3 (Example 3), Bendiocarb WP (Reference Example 1), Deltamethrin WG (Reference Example 4) Wall material: Mud Test insects: Anopheles gambiae Kisumu system treatment method: In April, a diluted solution of the above preparation is sprayed on the wall surface material with a tower sprayer so as to have a predetermined amount, and then dried at a temperature of 30 ° C. And stored in a constant temperature room with a humidity of 80%.
  • IVS Indoor Residual Spraying
  • Insecticidal test A standard WHO plastic cone was placed on the treated wall surface material, and a female Gambier anopheles female adult was placed on the lid. After exposure for 3 minutes, Gambier anopheles was placed in a separate container, and after 24 hours, life and death were investigated to calculate the mortality. This was continued from May to November, and the residual effect was evaluated (three consecutive systems).
  • Insecticidal test reagent for larvae of Culex pipiens molestus Compound test worm represented by formula (2): tiger squid (Culex pipiens molestus) Insecticidal test: 25 ml of water was put into a glass tube, and then 250 ⁇ l of an acetone solution of the compound represented by the formula (2) was added to prepare a predetermined concentration. Ten final-age larvae were released, and after 2 days, life and death were investigated, and the mortality rate was calculated. As a result, the compound represented by the formula (2) showed a death rate of 70% or more at 0.001 ppm.
  • composition according to the present embodiment has a long-term residual effect and is also effective against resistant pests, and therefore has high industrial applicability.

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Abstract

A blood-sucking-arthropod control method in which elements that form a living space are treated with a blood-sucking-arthropod control composition for treating elements that form a living space, the control composition containing at least one amide derivative represented by general formula (1) as an active ingredient. (In the formula, Q represents a phenyl group or a phenyl group substituted with a fluorine atom, R represents a hydrogen atom or a methyl group, and Y1 and Y2each independently represent a bromine atom, an iodine atom, or a trifluoromethyl group.)

Description

吸血性節足動物防除方法および居住空間形成物処理用吸血性節足動物防除組成物Blood-sucking arthropod control method and blood-sucking arthropod control composition for treating living space formation
　本発明は、吸血性節足動物が媒介する感染症の蔓延を防止するための、吸血性節足動物防除方法および居住空間形成物処理用吸血性節足動物防除組成物に関するものである。 The present invention relates to a blood-sucking arthropod control method and a blood-sucking arthropod control composition for treating living space formations for preventing the spread of infections mediated by blood-sucking arthropods.
　多くの吸血性節足動物が、人または動物に病原体を媒介して感染症を引き起こす。特に熱帯地域では、マラリア、デング熱など、蚊が媒介する感染症は、多くの人を死亡させており、また経済の発展も妨げている。これらの疾病媒介害虫を駆除する害虫防除方法として、害虫防除成分を含有する殺虫剤をスプレーする方法、屋内の壁の表面に接触性の殺虫剤を塗る方法、殺虫剤を蚊帳に浸漬させる方法等が用いられてきた。害虫防除成分としては、ピレスロイド系化合物、ネオニコチノイド系化合物等が知られている。 Many blood-sucking arthropods cause infections by transmitting pathogens to humans or animals. In tropical regions in particular, mosquito-borne infections such as malaria and dengue have killed many people and hindered economic development. Pest control methods to control these disease-borne pests include spraying an insecticide containing a pest control ingredient, applying a contact insecticide on the surface of an indoor wall, immersing the insecticide in a mosquito net, etc. Has been used. Known pest control components include pyrethroid compounds and neonicotinoid compounds.
　また、害虫防除作用を有するアミド誘導体として種々の化合物およびその使用方法が開示されている（例えば、特許文献１～５参照）。
　　　［特許文献１］　国際公開第２００５／２１４８８号パンフレット
　　　［特許文献２］　国際公開第２００５／７３１６５号パンフレット
　　　［特許文献３］　国際公開第２００６／１３７３７６号パンフレット
　　　［特許文献４］　国際公開第２００６／１３７３９５号パンフレット
　　　［特許文献５］　国際公開第２０１０／０１３５６７号パンフレット In addition, various compounds and methods for using them are disclosed as amide derivatives having a pest control action (see, for example, Patent Documents 1 to 5).
[Patent Document 1] International Publication No. 2005/21488 [Patent Document 2] International Publication No. 2005/73165 [Patent Document 3] International Publication No. 2006/137376 [Patent Document 4] International Publication No. 2006/137395 [Patent Document 5] International Publication No. 2010/013567 Pamphlet
　しかし、前記の害虫防除方法では持続性が十分ではなく、さらに、近年、ピレスロイド系化合物に対する抵抗性を獲得した疾病媒介害虫が出現し、大きな問題となっている。 However, the above-mentioned pest control method is not sufficiently durable, and in recent years, disease-borne pests that have acquired resistance to pyrethroid compounds have emerged and become a major problem.
　また、上記の特許文献１～５には疾病媒介害虫を防除しうる旨が記されているものの、具体的に有効な濃度および使用方法の詳細については開示されておらず、上記アミド誘導体を用いた害虫防除方法については、実質的に開示されていない。 In addition, although Patent Documents 1 to 5 describe that it is possible to control disease-borne pests, details of specific effective concentrations and methods of use are not disclosed, and the above amide derivatives are used. The method for controlling pests has not been substantially disclosed.
　したがって本発明の一態様は、持続性に優れ、かつ抵抗性害虫に対しても有効な、吸血性節足動物防除方法および居住空間形成物処理用吸血性節足動物防除組成物を提供することを課題とする。 Therefore, one embodiment of the present invention provides a blood-sucking arthropod control method and a blood-sucking arthropod control composition for treating living space formation, which are excellent in durability and effective against resistant pests. Is an issue.
　本発明者らは、上記課題を解決するために鋭意研究を重ねた結果、一般式（１）で表されるアミド誘導体を有効成分として含有する組成物によって、家屋壁面、蚊帳などの居住空間形成物を処理することにより、長期間害虫防除が可能でかつ抵抗性害虫に対しても有効であることを見出した。
　本発明の一形態は以下のとおりである。 As a result of intensive studies to solve the above problems, the present inventors have formed residential spaces such as house walls and mosquito nets with a composition containing an amide derivative represented by the general formula (1) as an active ingredient. The present inventors have found that pest control is possible for a long period of time and is effective against resistant pests.
One embodiment of the present invention is as follows.
＜１＞　下記一般式（１） <1> The following general formula (1)
Figure JPOXMLDOC01-appb-C000003
Figure JPOXMLDOC01-appb-C000003
（式中、Ｑはフェニル基またはフッ素原子で置換されたフェニル基を表す。Ｒは水素原子またはメチル基を表す。Ｙ１およびＹ２はそれぞれ独立に、臭素原子、ヨウ素原子またはトリフルオロメチル基を表す。）で表されるアミド誘導体の少なくとも１種を有効成分として含有する居住空間形成物処理用吸血性節足動物防除組成物によって、居住空間形成物を処理する吸血性節足動物防除方法。 (In the formula, Q represents a phenyl group or a phenyl group substituted with a fluorine atom. R represents a hydrogen atom or a methyl group. Y 1 and Y 2 are each independently a bromine atom, an iodine atom or a trifluoromethyl group. The blood-sucking arthropod control method which treats a living space formation with the blood-sucking arthropod control composition for living space formation processing which contains at least 1 sort (s) of the amide derivative represented by this as an active ingredient .
＜２＞　前記一般式（１）で表されるアミド誘導体が、２－フルオロ－３－（Ｎ－メチルベンズアミド）－Ｎ－（２－ブロモ－６－トリフルオロメチル－４－（ヘプタフルオロプロパン－２－イル）フェニル）ベンズアミドである＜１＞に記載の吸血性節足動物防除方法。 <2> The amide derivative represented by the general formula (1) is 2-fluoro-3- (N-methylbenzamide) -N- (2-bromo-6-trifluoromethyl-4- (heptafluoropropane-). The method for controlling blood-sucking arthropods according to <1>, which is 2-yl) phenyl) benzamide.
＜３＞　前記居住空間形成物が家屋壁面または蚊帳である、＜１＞または＜２＞に記載の吸血性節足動物防除方法。 <3> The blood-sucking arthropod control method according to <1> or <2>, wherein the living space formation is a house wall surface or a mosquito net.
＜４＞　前記居住空間形成物を処理する方法が散布または浸漬処理である、＜１＞～＜３＞のいずれか１つに記載の吸血性節足動物防除方法。 <4> The method for controlling blood-sucking arthropods according to any one of <1> to <3>, wherein the method for treating the living space formation is spraying or dipping treatment.
＜５＞　防除される吸血性節足動物が、ハエ目（Ｄｉｐｔｅｒａ）カ科（Ｃｕｌｉｃｉｄａｅ）であるＡｎｏｐｈｅｌｅｓ属昆虫、Ａｅｄｅｓ属昆虫およびＣｕｌｅｘ属昆虫からなる群より選択される少なくとも１種である、＜１＞～＜４＞のいずれか１つに記載の吸血性節足動物防除方法。 <5> The blood-sucking arthropod to be controlled is at least one selected from the group consisting of Anopheles insects, Aedes genus insects and Culex genus insects which are Diptera mosquitoes (Clicidae), < The method for controlling blood-sucking arthropods according to any one of 1> to <4>.
＜６＞　前記ハエ目（Ｄｉｐｔｅｒａ）カ科（Ｃｕｌｉｃｉｄａｅ）昆虫が、Ａｎｏｐｈｅｌｅｓ属昆虫である、＜５＞に記載の吸血性節足動物防除方法。 <6> The blood-sucking arthropod control method according to <5>, wherein the Dipteridae (Clicidae) insect is an Anopheles genus insect.
＜７＞　前記Ａｎｏｐｈｅｌｅｓ属昆虫が、ガンビエハマダラカ（Ａｎｏｐｈｅｌｅｓ　ｇａｍｂｉａｅ）およびシナハマダラカ（Ａｎｏｐｈｅｌｅｓ　ｓｉｎｅｎｓｉｓ）の少なくとも一方である、＜５＞または＜６＞に記載の吸血性節足動物防除方法。 <7> The blood-sucking arthropod control method according to <5> or <6>, wherein the Anopheles genus insect is at least one of Gambiae gambiae and Anopheles sinensis.
＜８＞　前記居住空間形成物処理用吸血性節足動物防除組成物は、ペルメトリン、アルファシペルメトリン、デルタメトリンおよびエトフェンプロックスからなる群より選択される少なくとも１種の化合物を更なる有効成分として含有する、＜１＞～＜７＞のいずれか１つに記載の吸血性節足動物防除方法。 <8> The blood-sucking arthropod control composition for treating living space formations contains, as a further active ingredient, at least one compound selected from the group consisting of permethrin, alpha cypermethrin, deltamethrin, and etofenprox. The blood-sucking arthropod control method according to any one of <1> to <7>.
＜９＞　前記居住空間形成物処理用吸血性節足動物防除組成物は水和剤又はフロアブル剤である、＜１＞～＜８＞のいずれか１つに記載の吸血性節足動物防除方法。 <9> The blood-sucking arthropod control method according to any one of <1> to <8>, wherein the blood-sucking arthropod control composition for treating living space formations is a wettable powder or a flowable agent. .
＜１０＞　＜１＞～＜９＞のいずれか１つに記載の吸血性節足動物防除方法に使用される吸血性節足動物防除組成物。 <10> A blood-sucking arthropod control composition used for the blood-sucking arthropod control method according to any one of <1> to <9>.
＜１１＞　居住空間形成物処理用である、＜１０＞に記載の吸血性節足動物防除組成物。 <11> The blood-sucking arthropod control composition according to <10>, which is for treatment of a living space formation.
＜１２＞　下記一般式（１） <12> The following general formula (1)
Figure JPOXMLDOC01-appb-C000004
Figure JPOXMLDOC01-appb-C000004
（式中、Ｑはフェニル基またはフッ素原子で置換されたフェニル基を表す。Ｒは水素原子またはメチル基を表す。Ｙ１およびＹ２はそれぞれ独立に、臭素原子、ヨウ素原子またはトリフルオロメチル基を表す。）で表されるアミド誘導体の少なくとも１種を有効成分として含有する、居住空間形成物処理用吸血性節足動物防除組成物。 (In the formula, Q represents a phenyl group or a phenyl group substituted with a fluorine atom. R represents a hydrogen atom or a methyl group. Y 1 and Y 2 are each independently a bromine atom, an iodine atom or a trifluoromethyl group. A blood-sucking arthropod control composition for treating living space formations, which contains at least one amide derivative represented by the formula:
＜１３＞　前記一般式（１）で表されるアミド誘導体が、２－フルオロ－３－（Ｎ－メチルベンズアミド）－Ｎ－（２－ブロモ－６－トリフルオロメチル－４－（ヘプタフルオロプロパン－２－イル）フェニル）ベンズアミドである＜１２＞に記載の居住空間形成物処理用吸血性節足動物防除組成物。 <13> The amide derivative represented by the general formula (1) is 2-fluoro-3- (N-methylbenzamide) -N- (2-bromo-6-trifluoromethyl-4- (heptafluoropropane-). The blood-sucking arthropod control composition for treating living space formations according to <12>, which is 2-yl) phenyl) benzamide.
＜１４＞　居住空間形成物としての家屋壁面または蚊帳の処理に用いられる、＜１２＞または＜１３＞に記載の居住空間形成物処理用吸血性節足動物防除組成物。 <14> The blood-sucking arthropod control composition for living space formation treatment according to <12> or <13>, which is used for treatment of a house wall or a mosquito net as a living space formation.
＜１５＞　吸血性節足動物としてのハエ目（Ｄｉｐｔｅｒａ）カ科（Ｃｕｌｉｃｉｄａｅ）であるＡｎｏｐｈｅｌｅｓ属昆虫、Ａｅｄｅｓ属昆虫およびＣｕｌｅｘ属昆虫からなる群より選択される少なくとも１種の防除に用いられる、＜１２＞～＜１４＞のいずれか１つに記載の居住空間形成物処理用吸血性節足動物防除組成物。 <15> Used for control of at least one species selected from the group consisting of Anopheles insects, Aedes insects, and Culex insects, which are Fliesidae (Diptera) as a blood-sucking arthropod, < The blood-sucking arthropod control composition for treating living space formations according to any one of 12> to <14>.
＜１６＞　前記ハエ目（Ｄｉｐｔｅｒａ）カ科（Ｃｕｌｉｃｉｄａｅ）昆虫が、Ａｎｏｐｈｅｌｅｓ属昆虫である、＜１５＞に記載の居住空間形成物処理用吸血性節足動物防除組成物。 <16> The blood-sucking arthropod control composition for treating living space formations according to <15>, wherein the Dipteridae (Clicidae) insect is an Anopheles insect.
＜１７＞　前記Ａｎｏｐｈｅｌｅｓ属昆虫が、ガンビエハマダラカ（Ａｎｏｐｈｅｌｅｓ　ｇａｍｂｉａｅ）およびシナハマダラカ（Ａｎｏｐｈｅｌｅｓ　ｓｉｎｅｎｓｉｓ）の少なくとも一方である、＜１５＞または＜１６＞に記載の居住空間形成物処理用吸血性節足動物防除組成物。 <17> The blood-sucking arthropod control for treating living space formations according to <15> or <16>, wherein the Anopheles genus insect is at least one of Gambier gambiae and Anopheles sinensis Composition.
＜１８＞　ペルメトリン、アルファシペルメトリン、デルタメトリンおよびエトフェンプロックスからなる群より選択される少なくとも１種の化合物を更なる有効成分として含有する、＜１２＞～＜１７＞のいずれか１つに記載の居住空間形成物処理用吸血性節足動物防除組成物。 <18> The composition according to any one of <12> to <17>, further comprising at least one compound selected from the group consisting of permethrin, alpha cypermethrin, deltamethrin, and etofenprox as a further active ingredient. A blood-sucking arthropod control composition for treating living space formations.
＜１９＞　水和剤又はフロアブル剤である、＜１２＞～＜１８＞のいずれか１つに記載の居住空間形成物処理用吸血性節足動物防除組成物。 <19> The blood-sucking arthropod control composition for living space formation treatment according to any one of <12> to <18>, which is a wettable powder or a flowable agent.
　本発明の一態様によれば、持続性に優れ、かつ抵抗性害虫に対しても有効な、吸血性節足動物防除方法および居住空間形成物処理用吸血性節足動物防除組成物を提供することができる。 According to one aspect of the present invention, there are provided a method for controlling blood-sucking arthropods and a composition for controlling blood-sucking arthropods for treating living space formation, which are excellent in durability and effective against resistant pests. be able to.
　本発明の一実施形態に係る居住空間形成物処理用吸血性節足動物防除組成物（以下、単に「組成物」とも称する。）は、下記一般式（１）で表されるアミド誘導体の少なくとも１種を有効成分として含有する。かかる構成であることにより、本実施形態に係る組成物によって居住空間形成物を処理した場合に、持続性に優れ、かつ抵抗性害虫に対しても有効であり、高い害虫防除効果を示すことができる。さらに、本発明の一実施形態に係る吸血性節足動物防除方法は、下記一般式（１）で表されるアミド誘導体の少なくとも１種を有効成分として含有する居住空間形成物処理用吸血性節足動物防除組成物によって、居住空間形成物を処理する。かかる構成であることにより、本実施形態に係る吸血性節足動物防除方法においても、持続性に優れ、かつ抵抗性害虫に対しても有効であり、高い害虫防除効果を示す。 A blood-sucking arthropod control composition for treating living space formation according to an embodiment of the present invention (hereinafter also simply referred to as “composition”) is at least an amide derivative represented by the following general formula (1): Contains one as an active ingredient. By being such a configuration, when the living space formation is treated with the composition according to the present embodiment, it is excellent in sustainability and effective against resistant pests, and exhibits a high pest control effect. it can. Furthermore, the blood-sucking arthropod control method according to one embodiment of the present invention includes a blood-sucking node for treating living space formations, which contains at least one amide derivative represented by the following general formula (1) as an active ingredient. The living space formation is treated with the paw animal control composition. With such a configuration, the blood-sucking arthropod control method according to the present embodiment is also excellent in sustainability and effective against resistant pests, and exhibits a high pest control effect.
Figure JPOXMLDOC01-appb-C000005
Figure JPOXMLDOC01-appb-C000005
　一般式（１）中、Ｑはフェニル基またはフッ素原子で置換されたフェニル基を表す。Ｒは水素原子またはメチル基を表す。Ｙ１およびＹ２はそれぞれ独立に、臭素原子、ヨウ素原子またはトリフルオロメチル基を表す。 In general formula (1), Q represents a phenyl group or a phenyl group substituted with a fluorine atom. R represents a hydrogen atom or a methyl group. Y 1 and Y 2 each independently represents a bromine atom, an iodine atom or a trifluoromethyl group.
　本実施形態にて用いる一般式（１）で表されるアミド誘導体は、その構造式中に、１個または複数個の不斉炭素原子または不斉中心を含む場合があり、２種以上の光学異性体が存在する場合もあるが、各々の光学異性体およびそれらが任意の割合で含まれる混合物をも全て包含するものである。また、本実施形態にて用いる一般式（１）で表されるアミド誘導体は、その構造式中に、炭素－炭素二重結合に由来する２種以上の幾何異性体が存在する場合もあるが、各々の幾何異性体およびそれらが任意の割合で含まれる混合物をも全て包含するものである。 The amide derivative represented by the general formula (1) used in the present embodiment may contain one or more asymmetric carbon atoms or asymmetric centers in the structural formula, and two or more kinds of optical derivatives may be used. Although isomers may exist, all of the optical isomers and a mixture in which they are contained in an arbitrary ratio are also included. The amide derivative represented by the general formula (1) used in the present embodiment may have two or more geometric isomers derived from a carbon-carbon double bond in the structural formula. And all geometric isomers and mixtures in which they are contained in any proportion.
　一般式（１）で表される化合物は、以下の式（２）で表される２－フルオロ－３－（Ｎ－メチルベンズアミド）－Ｎ－（２－ブロモ－６－トリフルオロメチル－４－（ヘプタフルオロプロパン－２－イル）フェニル）ベンズアミドであることが好ましい。 The compound represented by the general formula (1) is 2-fluoro-3- (N-methylbenzamide) -N- (2-bromo-6-trifluoromethyl-4-methyl represented by the following formula (2). (Heptafluoropropan-2-yl) phenyl) benzamide is preferred.
Figure JPOXMLDOC01-appb-C000006
Figure JPOXMLDOC01-appb-C000006
　本実施形態で用いる一般式（１）で表されるアミド誘導体は、例えば、国際公開第２０１０／０１３５６７号パンフレット等の明細書に記載の方法に準じて製造することができる。 The amide derivative represented by the general formula (1) used in the present embodiment can be produced, for example, according to the method described in the specification of International Publication No. 2010/013567.
　本実施形態に係る組成物および吸血性節足動物防除方法により防除できる吸血性節足動物として、具体的には例えば、以下の吸血性節足動物を挙げることができるが、本発明はこれらに限定されるものではない。 Specific examples of the blood-sucking arthropod that can be controlled by the composition and the method for controlling a blood-sucking arthropod according to the present embodiment include the following blood-sucking arthropods. It is not limited.
　ハエ目（Ｄｉｐｔｅｒａ）カ科（Ｃｕｌｉｃｉｄａｅ）昆虫として、
Ａｎｏｐｈｅｌｅｓ属である、Ａｎｏｐｈｅｌｅｓ　ｇａｍｂｉａｅ、Ａｎｏｐｈｅｌｅｓ　ａｒａｂｉｅｎｓｉｓ、Ａｎｏｐｈｅｌｅｓ　ｆｕｎｅｓｔｕｓ、Ａｎｏｐｈｅｌｅｓ　ｍｅｌａｓ、Ａｎｏｐｈｅｌｅｓ　ｍｉｎｉｍｕｓ、Ａｎｏｐｈｅｌｅｓ　ｄｉｒｕｓ、Ａｎｏｐｈｅｌｅｓ　ｓｔｅｐｈｅｎｓｉ、Ａｎｏｐｈｅｌｅｓ　ｓｉｎｅｎｓｉｓ、Ａｎｏｐｈｅｌｅｓ　ａｌｂｉｍａｎｕｓ等、
Ｃｕｌｅｘ属であるＣｕｌｅｘ　ｐｉｐｉｅｎｓ　ｍｏｌｅｓｔｕｓ、Ｃｕｌｅｘ　ｐｉｐｉｅｎｓ　ｐｉｐｉｅｎｓ、Ｃｕｌｅｘ　ｑｕｉｎｑｕｅｆａｓｃｉａｔｕｓ、Ｃｕｌｅｘ　ｐｉｐｉｅｎｓ　ｐａｌｌｅｎｓ、Ｃｕｌｅｘ　ｒｅｓｔｕａｎｓ、Ｃｕｌｅｘ　ｔａｒｓａｌｉｓ、Ｃｕｌｅｘ　ｍｏｄｅｓｔｕｓ、Ｃｕｌｅｘ　ｔｒｉｔａｅｎｉｏｒｈｙｎｃｈｕｓ等、
Ａｅｄｅｓ属である、Ａｅｄｅｓ　ａｅｇｙｐｔｉ、Ａｅｄｅｓ　ａｌｂｏｐｉｃｔｕｓ、Ａｅｄｅｓ　ｊａｐｏｎｉｃｕｓ、Ａｅｄｅｓ　ｖｅｘａｎｓ等、
アブ類、ハエ類、ブユ類、サシチョウバエ類、ヌカカ類、ツェツェバエ類、ユスリカ類、ノミ類、シラミ類、トコジラミ類、サシガメ類、ダニ類、マダニ類、等の昆虫が挙げられる。 As a Diptera (Clicidae) insect,
Anopheles genus, Anopheles gambiae, Anopheles arabiensis, Anopheles funestus, Anopheles melas, Anopheles minimus, Anopheles dibes, Anopheles staphines
Culex pipiens molestus, Culex pipiens pipiens, Culex quinquefasciatus, Culex pipiens pallens, Culex restus, Culex tarsitalis, Culex tarsalis
Aedes genus, Aedes aegypti, Aedes albopictus, Aedes Japanicus, Aedes vexans, etc.
Examples include insects such as abs, flies, flyfish, sand flies, nucifers, tsetse flies, chironomids, fleas, lices, bed bugs, sand turtles, ticks, ticks.
　本実施形態においては、防除効果の観点から、吸血性節足動物はハエ目カ科昆虫であることが好ましい。 In the present embodiment, it is preferable that the blood-sucking arthropod is a fly order mosquito insect from the viewpoint of controlling effect.
　本実施形態にて一般式（１）で表されるアミド誘導体を使用するにあたっては、通常適当な固体担体又は液体担体と混合し、さらに所望により界面活性剤、浸透剤、展着剤、増粘剤、保護コロイド剤、凍結防止剤、結合剤、固結防止剤、崩壊剤、消泡剤、防黴剤、分解防止剤等を添加して、液剤（soluble concentrate）、乳剤（emulsifiable concentrate）、水和剤（wettable powder）、フロアブル剤（flowable）、水溶剤（water soluble powder）、顆粒水和剤（water dispersible granule）、顆粒水溶剤（water soluble granule）、懸濁剤（suspension concentrate）、乳濁剤（concentrated emulsion）、サスポエマルジョン（suspoemulsion）、マイクロエマルジョン（microemulsion）、粉剤（dustable powder）、粒剤（granule）錠剤（tablet）、乳化性ゲル剤（emulsifiable gel）等任意の剤型の製剤にて実用に供することができる。また、省力化および安全性向上の観点から、上記任意の剤型の製剤を、水溶性カプセル、水溶性フィルムの袋等の水溶性包装体に封入して供することもできる。
　例えば、本実施形態に係る組成物は、水和剤又はフロアブル剤であってもよい。 In using the amide derivative represented by the general formula (1) in the present embodiment, it is usually mixed with a suitable solid carrier or liquid carrier, and further, a surfactant, a penetrating agent, a spreading agent, a thickening agent if desired. Agents, protective colloids, anti-freezing agents, binders, anti-caking agents, disintegrating agents, antifoaming agents, antifungal agents, anti-degradation agents, etc., and solubilized, emulsion (emulsifiable concentrate), Wettable powder, flowable, water-soluble powder, water dispersible granule, water-soluble granule, suspension concentrate, milk Any dosage form such as concentrated emulsion, suspoemulsion, microemulsion, dustable powder, granule tablet, emulsifiable gel For practical use in formulations Rukoto can. Further, from the viewpoint of labor saving and safety improvement, the preparations of any of the above dosage forms can be provided by being enclosed in a water-soluble package such as a water-soluble capsule or a water-soluble film bag.
For example, the composition according to the present embodiment may be a wettable powder or a flowable agent.
　本実施形態に係る組成物にて使用できる不活性担体としては固体であってもよく、液体であってもよい。 The inert carrier that can be used in the composition according to this embodiment may be a solid or a liquid.
　固体の不活性担体になりうる材料としては、例えば、ダイズ粉、穀物粉、木粉、樹皮粉、鋸粉、タバコ茎粉、クルミ殻粉、ふすま、繊維素粉末、植物エキス抽出後の残渣、粉砕合成樹脂などの合成重合体、粘土類（例えばカオリン、ベントナイト、酸性白土など）、タルク類（例えばタルク、ピロフィライドなど）、シリカ類（例えば珪藻土、珪砂、雲母、ホワイトカーボン〔含水微粉珪素、含水珪酸ともいわれる合成高分散珪酸で、製品により珪酸カルシウムを主成分として含むものもある。〕）、活性炭、イオウ粉末、軽石、焼成珪藻土、レンガ粉砕物（例えばクレー）、フライアッシュ、砂、炭酸カルシウム、リン酸カルシウムなどの無機鉱物性粉末、硫安、燐安、硝安、尿素、塩安などの化学肥料、堆肥などを挙げることができる。これらは単独で、もしくは二種以上の混合物の形で使用される。 Examples of materials that can be used as a solid inert carrier include soybean powder, cereal powder, wood powder, bark powder, saw powder, tobacco stem powder, walnut shell powder, bran, fiber powder, residue after extraction of plant extracts, Synthetic polymers such as pulverized synthetic resins, clays (eg kaolin, bentonite, acid clay), talc (eg talc, pyrophyllide, etc.), silicas (eg diatomaceous earth, silica sand, mica, white carbon (hydrous finely divided silicon, hydrous) Synthetic high-dispersion silicic acid, also called silicic acid, may contain calcium silicate as the main component depending on the product.]), Activated carbon, sulfur powder, pumice, calcined diatomaceous earth, brick ground (eg clay), fly ash, sand, calcium carbonate , Inorganic mineral powders such as calcium phosphate, chemical fertilizers such as ammonium sulfate, phosphoric acid, ammonium nitrate, urea, ammonium sulfate, compost, etc.These may be used alone or in the form of a mixture of two or more.
　液体の不活性担体になりうる材料としては、それ自体溶媒能を有するものの他、溶媒能を有さずとも補助剤（例えば、界面活性剤）の助けにより有効成分化合物を分散させうることとなるものから選択され、例えば、水、アルコール類（例えば、メタノール、エタノール、イソプロパノール、ブタノール、エチレングリコールなど）、ケトン類（例えばアセトン、メチルエチルケトン、メチルイソブチルケトン、ジイソブチルケトン、シクロヘキサノンなど）、エーテル類（例えばジエチルエーテル、ジオキサン、セロソルブ、ジイソプロピルエーテル、テトラヒドロフランなど）、脂肪族炭化水素類（例えばケロシン、鉱油など）、芳香族炭化水素類（例えばベンゼン、トルエン、キシレン、ソルベントナフサ、アルキルナフタレンなど）、ハロゲン化炭化水素類（例えばジクロロメタン、クロロホルム、四塩化炭素、クロロベンゼンなど）、エステル類（例えば酢酸エチル、酢酸ブチル、プロピオン酸エチル、フタル酸ジイソブチル、フタル酸ジブチル、フタル酸ジオクチルなど）、アミド類（例えばジメチルホルムアミド、ジエチルホルムアミド、ジメチルアセトアミドなど）、ニトリル類（例えばアセトニトリルなど）を挙げることができる。これらは単独で、もしくは２種以上の混合物の形で使用される。 As a material that can be a liquid inert carrier, the active ingredient compound can be dispersed with the aid of an auxiliary agent (for example, a surfactant) in addition to those having a solvent ability per se, and having no solvent ability. For example, water, alcohols (eg, methanol, ethanol, isopropanol, butanol, ethylene glycol, etc.), ketones (eg, acetone, methyl ethyl ketone, methyl isobutyl ketone, diisobutyl ketone, cyclohexanone, etc.), ethers (eg, Diethyl ether, dioxane, cellosolve, diisopropyl ether, tetrahydrofuran, etc.), aliphatic hydrocarbons (eg kerosene, mineral oil, etc.), aromatic hydrocarbons (eg benzene, toluene, xylene, solvent naphtha, alkylnaphthalene, etc.) Halogenated hydrocarbons (eg dichloromethane, chloroform, carbon tetrachloride, chlorobenzene, etc.), esters (eg ethyl acetate, butyl acetate, ethyl propionate, diisobutyl phthalate, dibutyl phthalate, dioctyl phthalate, etc.), amides (For example, dimethylformamide, diethylformamide, dimethylacetamide, etc.) and nitriles (for example, acetonitrile etc.) can be mentioned. These may be used alone or in the form of a mixture of two or more.
　これら固体担体および液体担体を、単独で用いても２種以上を併用してもよい。 These solid carriers and liquid carriers may be used alone or in combination of two or more.
　界面活性剤としては、例えばポリオキシエチレン（モノまたはジ）アルキルエーテル、ポリオキシエチレンアルキル（モノまたはジ）フェニルエーテル、ポリオキシエチレン（モノ、ジまたはトリ）スチリルフェニルエーテル、ポリオキシエチレンポリオキシプロピレンブロックコポリマー、ポリオキシエチレン脂肪酸（モノまたはジ）エステル、ソルビタン脂肪酸エステル、ポリオキシエチレンソルビタン脂肪酸エステル、ヒマシ油エチレンオキサイド付加物、アセチレングリコール、アセチレンアルコール、アセチレングリコールのエチレンオキサイド付加物、アセチレンアルコールのエチレンオキサイド付加物およびアルキルグリコシド等のノニオン性界面活性剤、アルキル硫酸エステル塩、アルキルベンゼンスルホン酸塩、リグニンスルホン酸塩、アルキルスルホコハク酸塩、ジアルキルスルホコハク酸塩、ナフタレンスルホン酸塩、アルキルナフタレンスルホン酸塩、ナフタレンスルホン酸のホルマリン縮合物（ホルムアルデヒド縮合物）の塩、アルキルナフタレンスルホン酸のホルマリン縮合物（ホルムアルデヒド縮合物）の塩、ポリオキシエチレンアルキルエーテル硫酸または燐酸エステル塩、ポリオキシエチレン（モノまたはジ）アルキルフェニルエーテル硫酸または燐酸エステル塩、ポリオキシエチレン（モノ、ジまたはトリ）スチリルフェニルエーテル硫酸または燐酸エステル塩、ポリカルボン酸塩（例えば、ポリアクリル酸塩、ポリマレイン酸塩およびマレイン酸とオレフィンとの共重合物等）およびポリスチレンスルホン酸塩等のアニオン性界面活性剤、アルキルアミン塩およびアルキル４級アンモニウム塩等のカチオン性界面活性剤、アミノ酸型およびベタイン型等の両性界面活性剤、シリコーン系界面活性剤ならびにフッ素系界面活性剤が挙げられる。 Examples of the surfactant include polyoxyethylene (mono or di) alkyl ether, polyoxyethylene alkyl (mono or di) phenyl ether, polyoxyethylene (mono, di or tri) styryl phenyl ether, polyoxyethylene polyoxypropylene Block copolymer, polyoxyethylene fatty acid (mono or di) ester, sorbitan fatty acid ester, polyoxyethylene sorbitan fatty acid ester, castor oil ethylene oxide adduct, acetylene glycol, acetylene alcohol, ethylene oxide adduct of acetylene glycol, ethylene of acetylene alcohol Nonionic surfactants such as oxide adducts and alkyl glycosides, alkyl sulfate esters, alkylbenzene sulfonates, ligni Sulfonate, alkylsulfosuccinate, dialkylsulfosuccinate, naphthalenesulfonate, alkylnaphthalenesulfonate, salt of formalin condensate of naphthalenesulfonic acid (formaldehyde condensate), formalin condensate of alkylnaphthalenesulfonic acid (formaldehyde) Condensates), polyoxyethylene alkyl ether sulfuric acid or phosphoric acid ester salts, polyoxyethylene (mono or di) alkyl phenyl ether sulfuric acid or phosphoric acid ester salts, polyoxyethylene (mono, di or tri) styryl phenyl ether sulfuric acid or phosphoric acid Anionic surfactants such as ester salts, polycarboxylates (for example, polyacrylates, polymaleates and copolymers of maleic acid and olefins) and polystyrene sulfonates Cationic surfactants such as alkylamine salts and alkyl quaternary ammonium salts, amphoteric surfactants of an amino acid type and betaine type, etc., and silicone-based surfactants and fluorinated surfactants.
　これら界面活性剤の含有量は、特に限定されるものではないが、製剤１００重量部に対し、通常０．０５～２０重量部の範囲が望ましい。また、これら界面活性剤を、単独で用いても２種以上を併用してもよい。 The content of these surfactants is not particularly limited, but is usually in the range of 0.05 to 20 parts by weight per 100 parts by weight of the preparation. These surfactants may be used alone or in combination of two or more.
　増粘剤としては、例えばキサンタンガム、ウエランガム、グアーガム、トラガントガム、アラビアガム等の天然ガム類；スメクタイト、セピオライト、アタパルジャイト、ラポナイト、モンモリロナイト、ヘクトライト等の無機鉱物質の微粉；カルボキシメチルセルロース、ヒドロキシエチルセルロース、カルボキシエチルセルロース、メチルセルロース、ヒドロキシプロピルセルロース等のセルロース誘導体およびその塩；種々のグレードのデキストリン、カルボキシメチルスターチナトリウム塩等の澱粉誘導体；アルギン酸ナトリウム、カゼイン酸ナトリウム等の天然物およびその誘導体；ポリビニルアルコール、ポリアクリル酸、およびそれら誘導体、ポリビニルピロリドン等の水溶性合成高分子などが挙げられる。また、これら増粘剤は、単独で用いても２種以上を併用してもよい。 Examples of thickeners include natural gums such as xanthan gum, welan gum, guar gum, tragacanth gum, and gum arabic; fine powders of inorganic minerals such as smectite, sepiolite, attapulgite, laponite, montmorillonite, hectorite; carboxymethylcellulose, hydroxyethylcellulose, carboxy Cellulose derivatives such as ethyl cellulose, methyl cellulose, hydroxypropyl cellulose and salts thereof; starch derivatives such as various grades of dextrin and sodium carboxymethyl starch; natural products such as sodium alginate and sodium caseinate and derivatives thereof; polyvinyl alcohol, polyacryl Examples thereof include acids and derivatives thereof, and water-soluble synthetic polymers such as polyvinylpyrrolidone. Moreover, these thickeners may be used independently or may use 2 or more types together.
　保護コロイド剤としては、例えばメチルセルロース、ヒドロキシエチルセルロース、ヒドロキシプロピルセルロース、ヒドロキシプロピルメチルセルロースおよびカルボキシメチルセルロース等の水溶性セルロース類、ポリエチレングリコール、ポリプロピレングリコール等のポリアルキレングリコール、ポリビニルアルコール、ポリビニルピロリドン、グアーガム、アラビアガム、ゼラチン、ポリアクリル酸塩、アルギン酸塩等が挙げられる。また、これら保護コロイド剤は、単独で用いても２種以上を併用してもよい。 Examples of the protective colloid agent include water-soluble celluloses such as methylcellulose, hydroxyethylcellulose, hydroxypropylcellulose, hydroxypropylmethylcellulose and carboxymethylcellulose, polyalkylene glycols such as polyethylene glycol and polypropylene glycol, polyvinyl alcohol, polyvinyl pyrrolidone, guar gum and gum arabic. , Gelatin, polyacrylate, alginate and the like. Moreover, these protective colloid agents may be used alone or in combination of two or more.
　凍結防止剤としては、例えばエチレングリコール、ジエチレングリコール、プロピレングリコール、グリセリン等が挙げられる。これら凍結防止剤は、単独で用いても２種以上を併用してもよい。 Examples of the antifreezing agent include ethylene glycol, diethylene glycol, propylene glycol, glycerin and the like. These antifreeze agents may be used alone or in combination of two or more.
　消泡剤としては、例えばシリコーン系、アセチレングリコール系、フッ素系、脂肪酸系等が挙げられる。これら消泡剤は、単独で用いても２種以上を併用してもよい。 Examples of antifoaming agents include silicone, acetylene glycol, fluorine, and fatty acid. These antifoaming agents may be used alone or in combination of two or more.
　防黴剤としては、例えばベンゾチアゾール誘導体、ソルビン酸、ソルビン酸カリウム、ｐ―オキシ安息香酸ブチル等が挙げられる。これら防黴剤は、単独で用いても２種以上を併用してもよい。 Examples of the antifungal agent include benzothiazole derivatives, sorbic acid, potassium sorbate, butyl p-oxybenzoate, and the like. These antifungal agents may be used alone or in combination of two or more.
　また本実施形態に係る組成物は、一般式（１）で表されるアミド誘導体に加えて、一般的に知られている他の殺虫成分（害虫防除成分）および共力剤の少なくとも一方をさらに１種または２種以上含有していてもよい。
　他の殺虫成分としては、例えば、
アクリナトリン、ペルメトリン、フェノトリン、ｄ－フェノトリン、アレスリン、ｄ－アレスリン、ｄｄ-アレスリン、ピレトリン、プラレトリン、シフェノトリン、シフルトリン、ベータシフルトリン、ビフェントリン、シクロプロトリン、シハロトリン、ラムダシハロトリン、ガンマシハロトリン、シペルメトリン、シグマシペルメトリン、アルファシペルメトリン、ゼータシペルメトリン、ジメフルトリン、エンペントリン、デルタメトリン、テラレスリン、テフルトリン、フェンバレレート、エスフェンバレレート、フルシトリネート、フルフェンプロックス、フルメトリン、フルバリネート、タウフルバリネート、プロフルトリン、ハルフェンプロックス、イミプロトリン、ベンフルスリン、レスメトリン、ｄ-レスメトリン、シラフルオフェン、トラロメトリン、テトラメトリン、ｄ-テトラメトリン、フラメトリン、メトフルトリン、フェンプロパトリン、トランスフルスリン、エトフェンプロックス等のピレスロイド系化合物、
アセフェート、ブタチオホス、クロルエトキシホス、クロルフェンビンホス、クロルピリホス、クロルピリホスメチル、シアノホス、ダイアジノン、ＤＣＩＰ、ジクロフェンチオン、ジクロルボス、ジメトエート、ジメチルビンホス、ジスルホトン、ＥＰＮ、エチオン、エトプロホス、エトリムホス、フェンチオン、フェニトロチオン、ホスチアゼート、ホルモチオン、イソフェンホス、イソキサチオン、マラチオン、メスルフェンホス、メチダチオン、モノクロトホス、ナレッド、パラチオン、ホサロン、ホスメット、ピリミホスメチル、ピリダフェンチオン、キナルホス、フェントエート、プロフェノホス、プロパホス、プロチオホス、ピラクロホス、サリチオン、スルプロホス、テメホス、テルブホス、トリクロルホン、カズサホス等の有機リン系化合物、
フィプロニル等のＮ－フェニルピラゾール系化合物、
アラニカルブ、ベンフラカルブ、ＢＰＭＣ、カルバリル、カルボフラン、カルボスルファン、クロエトカルブ、エチオフェンカルブ、フェノブカルブ、メソミル、メチオカルブ、ＮＡＣ、オキサミル、ピリミカーブ、プロポキスル、ＸＭＣ、チオジカルブ、キシリカルブ、アルジカルブ等のカーバメート系化合物、
イミダクロプリド、クロチアニジン、チアメトキサム、ジノテフラン等のネオニコチノイド系化合物、
ピリプロキシフェン、メトプレン、ハイドロプレン、フェノキシカルブ、エトキサゾール、クロルフルアズロン、トリアズロン、ノバルロン、ヘキサフルムロン、ジフルベンズロン、シロマジン、フルフェノクスロン、テフルベンズロン、トリフルムロン、ルフェヌロン等の昆虫成長制御剤、
ミルベマイシン、アバメクチン、イベルメクチン等のマクロライド系化合物、
を例示することができる。
　共力剤としては、例えば、
ピペロニルブトキサイド、Ｏ－プロパルギル－Ｏ－プロピルフェニルホスホネート（ＮＩＡ１６３８８）、イソボルニルチオシアノアセテート（ＩＢＴＡ）、Ｎ－（２－エチルヘキシル）－ビシクロ［２．２．１］－ヘプタ－５－エン－２，３－ジカルボキシイミド（ＭＧＫ－２６４）、２，２’，３，３，３，３’，３’，３’－オクタクロロジプロピルエーテル（Ｓ－４２１）、サイネピリン５００、プロピルアイソム、ピペロニルシクロネン、セサモリン、セサメックス、セサミン、サルホキサイド、サフロキサン、安息香酸ベンジル等の化合物、
を例示することができる。
　本実施形態に係る組成物は、吸血性節足動物に対する殺虫効果により優れる傾向がある点から、他の殺虫成分として、ペルメトリン、アルファシペルメトリン、デルタメトリンおよびエトフェンプロックスからなる群より選択される少なくとも１種の化合物を、一般式（１）で表されるアミド誘導体の他に有効成分として更に含有してもよい。 In addition to the amide derivative represented by the general formula (1), the composition according to this embodiment further includes at least one of other generally known insecticidal components (insect controlling components) and synergists. You may contain 1 type, or 2 or more types.
Other insecticidal ingredients include, for example:
Acrinathrin, permethrin, phenothrin, d-phenothrin, allethrin, dd-alleslin, dd-alleslin, pyrethrin, praretrin, ciphenothrin, cyfluthrin, beta-cyfluthrin, bifenthrin, cycloprotorin, cyhalothrin, lambda cihalothrin, gamma cyhalothrin , Cypermethrin, sigmacipermethrin, alpha cypermethrin, zetacypermethrin, dimefluthrin, empentrin, deltamethrin, terrareslin, tefluthrin, fenvalerate, esfenvalerate, flucitrinate, flufenprox, flumethrin, fulvalinate, taufulvalinate, Profluthrin, Halfenprox, Imiprothrin, Benfluthrin, Resmethrin, d-resmethrin, Sila Ruofen, tralomethrin, tetramethrin, d-tetramethrin, furamethrin, metofluthrin, fenpropathrin, transfluthrin, pyrethroid compounds such as etofenprox,
Acephate, Butathiophos, Chlorethoxyphos, Chlorfenvinphos, Chlorpyrifos, Chlorpyrifosmethyl, Cyanophos, Diazinon, DCIP, Diclofenthion, Dichlorvos, Dimethoate, Dimethylvinphos, Disulfoton, EPN, Ethion, Etoprophos, Etrimphos, Fentione, Fenitrothion, Phostiazete, Formothion, isofenphos, isoxathion, malathion, mesulfenphos, methidathion, monocrotophos, nared, parathion, hosalon, phosmet, pyrimifosmethyl, pyridafenthion, quinalphos, phentoate, profenofos, propopas, prothiophos, pyracrophos, salicione, sulfophos, tetrifos etc Organophosphorus compounds,
N-phenylpyrazole compounds such as fipronil,
Carbamate compounds such as alanicarb, benfuracarb, BPMC, carbaryl, carbofuran, carbosulfan, cloetocarb, etiophencarb, fenobucarb, mesomil, methiocarb, NAC, oxamyl, pirimicurve, propoxur, XMC, thiodicarb, xilicarb, aldicarb
Neonicotinoid compounds such as imidacloprid, clothianidin, thiamethoxam, dinotefuran,
Insect growth control agents such as pyriproxyfen, metoprene, hydroprene, phenoxycarb, etoxazole, chlorfluazuron, triazuron, novallon, hexaflumuron, diflubenzuron, cyromazine, flufenoxuron, teflubenzuron, triflumuron, lufenuron,
Macrolide compounds such as milbemycin, abamectin, ivermectin,
Can be illustrated.
As a synergist, for example,
Piperonyl butoxide, O-propargyl-O-propylphenylphosphonate (NIA16388), isobornylthiocyanoacetate (IBTA), N- (2-ethylhexyl) -bicyclo [2.2.1] -hepta-5 En-2,3-dicarboximide (MGK-264), 2,2 ′, 3,3,3,3 ′, 3 ′, 3′-octachlorodipropyl ether (S-421), sinepiline 500, propyl Compounds such as isome, piperonylcyclonene, sesamolin, sesamex, sesamin, sulfoxide, safroxan, benzyl benzoate,
Can be illustrated.
The composition according to the present embodiment tends to be more excellent in insecticidal effect on blood-sucking arthropods, and therefore, as other insecticidal components, at least selected from the group consisting of permethrin, alpha cypermethrin, deltamethrin and etofenprox. In addition to the amide derivative represented by the general formula (1), one kind of compound may be further contained as an active ingredient.
　一般式（１）で表されるアミド誘導体と他の殺虫成分および共力剤の合計との重量比は、一般式（１）で表されるアミド誘導体１重量部に対し、他の殺虫成分が通常０．０１～１００重量部、好ましくは０．０２～５０重量部である。 The weight ratio of the amide derivative represented by the general formula (1) to the total of other insecticidal components and synergists is such that the other pesticidal components are contained in 1 part by weight of the amide derivative represented by the general formula (1). The amount is usually 0.01 to 100 parts by weight, preferably 0.02 to 50 parts by weight.
　本実施形態に係る組成物の有効成分量は、通常粉剤では０．１～２０重量％、乳剤では５～５０重量％、水和剤では３～９０重量％、粒剤では０．１～２０重量％、フロアブル製剤では５～９０重量％、顆粒水和剤では３～９０重量％であることが好ましい。一方それぞれの剤型における担体の量は、通常粉剤では６０～９９．９重量％、乳剤では４０～９５重量％、水和剤では１０～９０重量％、粒剤では８０～９９．９重量％、フロアブル製剤では１０～９５重量％、顆粒水和剤では１０～９０重量％であることが好ましい。また、補助剤の量は、通常粉剤では０．１～２０重量％、乳剤では１～２０重量％、水和剤では０．１～２０重量％、粒剤では０．１～２０重量％、フロアブル製剤では０．１～２０重量％、顆粒水和剤では０．１～２０重量％であることが好ましい。 The amount of the active ingredient of the composition according to this embodiment is usually 0.1 to 20% by weight for powders, 5 to 50% by weight for emulsions, 3 to 90% by weight for wettable powders, and 0.1 to 20 for granules. It is preferably 5% by weight, 5% to 90% by weight for flowable preparations, and 3% to 90% by weight for wettable granules. On the other hand, the amount of carrier in each dosage form is usually 60 to 99.9% by weight for powders, 40 to 95% by weight for emulsions, 10 to 90% by weight for wettable powders, and 80 to 99.9% by weight for granules. The flowable preparation is preferably 10 to 95% by weight, and the granular wettable powder is preferably 10 to 90% by weight. The amount of the adjuvant is usually 0.1 to 20% by weight for powders, 1 to 20% by weight for emulsions, 0.1 to 20% by weight for wettable powders, 0.1 to 20% by weight for granules, It is preferably 0.1 to 20% by weight for flowable preparations and 0.1 to 20% by weight for granular wettable powders.
　本実施形態に係る吸血性節足動物防除方法においては、本実施形態に係る組成物を、そのまま使用してもよく、水などで適宜希釈し、あるいは懸濁させて使用してもよい。その使用量は通常、有効成分０．０００１～５０００ｐｐｍの濃度で使用することが好ましく、０．０１～１０００ｐｐｍの濃度で使用することがより好ましい。 In the blood-sucking arthropod control method according to the present embodiment, the composition according to the present embodiment may be used as it is, or may be used by diluting or suspending it appropriately with water or the like. The amount of the active ingredient is usually preferably used at a concentration of 0.0001 to 5000 ppm, more preferably 0.01 to 1000 ppm.
　本明細書において、居住空間とは人および家畜の少なくともいずれかが入る空間であり、居住空間形成物としては家屋壁面、天井、柱、欄間、窓、扉、テント、蚊帳等が挙げられる。 In this specification, the living space is a space into which at least one of humans and livestock enters, and examples of the living space formation include a house wall surface, a ceiling, a pillar, a column, a window, a door, a tent, and a mosquito net.
　本実施形態に係る組成物によって家屋壁面を処理する場合、家屋壁面に散布、塗布、蒸散等の処理をすればよい。また、散布、塗布、蒸散、浸漬、注入等された資材を家屋壁面として使用することも家屋壁面を処理する場合に該当する。 When the wall surface of a house is treated with the composition according to the present embodiment, the house wall surface may be treated such as spraying, coating, and transpiration. Moreover, using the material spread | sprayed, apply | coated, transpiration, immersion, injection | pouring, etc. as a house wall surface also corresponds when processing a house wall surface.
　家屋壁面の材質としては、コンクリート（セメント）、レンガ、竹、木材、タイル、セラミック、泥土等が挙げられ、天井の材質としては、わらぶき、トタン、コンクリート（セメント）、竹、木材等が挙げられるが、本発明はこれらに限定されるものではない。 The material of the house wall is concrete (cement), brick, bamboo, wood, tile, ceramic, mud, etc. The material of the ceiling is thatch, tin, concrete (cement), bamboo, wood, etc. The present invention is not limited to these examples.
　本実施形態に係る組成物によって蚊帳を処理する場合、本実施形態に係る組成物に蚊帳を浸漬してもよく、あるいは本実施形態に係る組成物を、水などで適宜希釈した溶液または懸濁させた薬液に蚊帳を浸漬してもよく、他にも蚊帳に散布、塗布等の処理を施してもよい。 When treating a mosquito net with the composition according to the present embodiment, the mosquito net may be immersed in the composition according to the present embodiment, or a solution or suspension in which the composition according to the present embodiment is appropriately diluted with water or the like. The mosquito net may be soaked in the chemical solution thus applied, and other treatments such as spraying and coating may be applied to the mosquito net.
　蚊帳の材質としては樹脂、天然繊維、ガラス繊維等の繊維材料などが挙げられ、中でも樹脂が好ましい。ここで、天然繊維としては、例えば、パルプ、セルロース、綿、麻、毛等が挙げられる。
　樹脂としては、熱可塑性樹脂が好ましい。熱可塑性樹脂としては、ポリオレフィン系樹脂、ポリビニルアルコール、ポリ酢酸ビニル、ポリカーボネート、ポリエステル、ポリアミド（例えば、ナイロン）、ポリスチレン、ポリメタクリル酸メチル、アクリロニトリル－ブタジエン－スチレン共重合体、又はポリ塩化ビニルなどが挙げられる。
　中でも、熱可塑性樹脂としては、ポリオレフィン系樹脂が好ましい。ポリオレフィン系樹脂としては、次の（i）～（iii）に挙げられた化合物が好ましい。
（ｉ）α－オレフィンの単独重合体：例えば、ポリエチレン、ポリプロピレンなど。
（ii）エチレン－α－オレフィン共重合体：例えば、エチレン－プロピレン共重合体、エチレン－１－ブテン共重合体、エチレン－４－メチル－１－ペンテン共重合体、又はエチレン－ヘキセン共重合体など。
（iii）エチレン性不飽和結合を有する有機カルボン酸誘導体とエチレンとの共重合体：例えば、エチレン－メチルメタクリレート共重合体、エチレン－酢酸ビニル共重合体、エチレン－アクリル酸共重合体、エチレン－酢酸ビニル－メチルメタクリレート共重合体など。 Examples of the material of the mosquito net include resin, natural fiber, fiber material such as glass fiber, and the like, and among them, resin is preferable. Here, examples of natural fibers include pulp, cellulose, cotton, hemp, and hair.
As the resin, a thermoplastic resin is preferable. Examples of the thermoplastic resin include polyolefin resin, polyvinyl alcohol, polyvinyl acetate, polycarbonate, polyester, polyamide (for example, nylon), polystyrene, polymethyl methacrylate, acrylonitrile-butadiene-styrene copolymer, and polyvinyl chloride. Can be mentioned.
Especially, as a thermoplastic resin, polyolefin resin is preferable. As the polyolefin resin, the compounds listed in the following (i) to (iii) are preferable.
(I) α-olefin homopolymer: polyethylene, polypropylene, etc.
(Ii) ethylene-α-olefin copolymer: for example, ethylene-propylene copolymer, ethylene-1-butene copolymer, ethylene-4-methyl-1-pentene copolymer, or ethylene-hexene copolymer Such.
(Iii) Copolymer of an organic carboxylic acid derivative having an ethylenically unsaturated bond and ethylene: for example, ethylene-methyl methacrylate copolymer, ethylene-vinyl acetate copolymer, ethylene-acrylic acid copolymer, ethylene- Vinyl acetate-methyl methacrylate copolymer.
　本実施形態に係る組成物が処理された蚊帳の材質を用いて、蚊帳を成形してもよい。
　さらに、一般式（１）で表されるアミド誘導体を含有する樹脂を用いて紡糸し、得られた糸を織って蚊帳としてもよい。 You may shape | mold a mosquito net using the material of the mosquito net which the composition concerning this embodiment was processed.
Furthermore, it is good also as a mosquito net by spinning using the resin containing the amide derivative represented by General formula (1), and woven the obtained thread | yarn.
　上記居住空間形成物の表面に担持させる有効成分量は、適用時期、適用場所、処理方法等に応じて、適宜調整してもよく、例えば、０．１～３０００ｍｇ／ｍ２であることが好ましく、好ましくは１～５００ｍｇ／ｍ２であることがより好ましい。 The amount of the active ingredient carried on the surface of the living space formation may be appropriately adjusted according to the application time, application place, treatment method, etc., and is preferably 0.1 to 3000 mg / m 2 , for example. More preferably, it is 1 to 500 mg / m 2 .
　本実施形態に係る組成物は、居住空間形成物処理用ではあるが、吸血性節足動物、例えば、ハエ目カ科昆虫の幼虫が生息する湖沼、湿地、水田、溜池、浄化槽、排水路等の水系環境中に施用することで、予防的にマラリア、デング熱、ジカ熱等の感染を防ぐことが期待できる。 The composition according to the present embodiment is for living space formation treatment, but is a blood-sucking arthropod, for example, a lake, a wetland, a paddy field, a reservoir, a septic tank, a drainage channel, etc. It can be expected to prevent infections such as malaria, dengue fever and zika fever prophylactically.
　また、本実施形態に係る組成物は、必要に応じて処理時に他種の各種殺虫剤、殺ダニ剤、殺線虫剤、殺菌剤、共力剤等と混合して使用してもよい。 In addition, the composition according to the present embodiment may be used by mixing with various other insecticides, acaricides, nematicides, bactericides, synergists and the like as needed during processing.
　次に、本実施形態に係る組成物である製剤の具体例を示すが、本発明はこれらに限定されるものではない。なお、以下の「部」という記載は、「重量部」を示す。 Next, specific examples of the preparation that is the composition according to the present embodiment will be shown, but the present invention is not limited thereto. In addition, the following description of “parts” indicates “parts by weight”.
　まず、以下の調製例１～調製例３に示すように、ブロフラニリドスラリー、増粘剤溶液Ａおよび増粘剤溶液Ｂを調製した。
＜調製例１＞
　式（２）で表される化合物（２－フルオロ－３－（Ｎ－メチルベンズアミド）－Ｎ－（２－ブロモ－６－トリフルオロメチル－４－（ヘプタフルオロプロパン－２－イル）フェニル）ベンズアミド）５０．０部、ポリオキシエチレンスチリル化フェノール燐酸エステル塩２.０部、ジオクチルスルホコハク酸塩１．０部、シリコーン消泡剤０．１部および水４６．９部、以上を均一に混合し、湿式粉砕してブロフラニリドスラリーを得た。
＜調製例２＞
　キサンタンガム０．４７部、ベンゾチアゾール誘導体０．３３部、プロピレングリコール１３．３３部、水８５．８７部、以上を均一に混合して増粘剤溶液Ａを得た。
＜調製例３＞
　キサンタンガム０．４７部、ベンゾチアゾール誘導体０．５０部、プロピレングリコール１８．７５部、水８０．２８部、以上を均一に混合して増粘剤溶液Ｂを得た。 First, as shown in the following Preparation Examples 1 to 3, a brofuranilide slurry, a thickener solution A, and a thickener solution B were prepared.
<Preparation Example 1>
Compound represented by formula (2) (2-fluoro-3- (N-methylbenzamide) -N- (2-bromo-6-trifluoromethyl-4- (heptafluoropropan-2-yl) phenyl) benzamide ) 50.0 parts, 2.0 parts of polyoxyethylene styrylated phenol phosphate salt, 1.0 part of dioctyl sulfosuccinate, 0.1 part of silicone antifoaming agent and 46.9 parts of water were mixed uniformly. And wet milling to obtain a brofuranilide slurry.
<Preparation Example 2>
Thickener solution A was obtained by uniformly mixing 0.47 parts of xanthan gum, 0.33 parts of benzothiazole derivative, 13.33 parts of propylene glycol, and 85.87 parts of water.
<Preparation Example 3>
Thickener solution B was obtained by uniformly mixing 0.47 parts xanthan gum, 0.50 parts benzothiazole derivative, 18.75 parts propylene glycol, and 80.28 parts water.
［実施例１］
＜製剤例１＞
　式（２）で表される化合物５０．０部、ジエチレングリコールモノドデシルエーテル（ポリオキシエチレンモノアルキルエーテル）２．５部、ノナエチレングリコールモノドデシルエーテル（ポリオキシエチレンモノアルキルエーテル）２．５部、ポリビニルアルコール２．０部、カオリン３８．０部、ホワイトカーボン５．０部、以上を均一に粉砕混合して水和剤を得た。 [Example 1]
<Formulation example 1>
50.0 parts of the compound represented by the formula (2), 2.5 parts of diethylene glycol monododecyl ether (polyoxyethylene monoalkyl ether), 2.5 parts of nonaethylene glycol monododecyl ether (polyoxyethylene monoalkyl ether), Polyvinyl alcohol (2.0 parts), kaolin (38.0 parts), white carbon (5.0 parts) were uniformly ground and mixed to obtain a wettable powder.
［実施例２］
＜製剤例２＞
　式（２）で表される化合物５０．０部、アルキル硫酸エステル塩３．０部、ジアルキルスルホコハク酸塩４．０部、ポリオキシエチレンモノアルキルエーテル３．０部、ポリビニルアルコール２．０部、カオリン３８．０部、以上を均一に粉砕混合して水和剤を得た。 [Example 2]
<Formulation example 2>
50.0 parts of the compound represented by the formula (2), 3.0 parts of alkyl sulfate ester salt, 4.0 parts of dialkyl sulfosuccinate, 3.0 parts of polyoxyethylene monoalkyl ether, 2.0 parts of polyvinyl alcohol, 38.0 parts of kaolin and the above were ground and mixed uniformly to obtain a wettable powder.
［実施例３］
＜製剤例３＞
　式（２）で表される化合物５０．０部、ジアルキルスルホコハク酸塩４．０部、ポリオキシエチレンアルキルエーテル３．０部、アルキルナフタレンスルホン酸のホルマリン縮合物（ホルムアルデヒド縮合物）の塩３．０部、カオリン３９．５部、シリコーン系消泡剤０．５部、以上を均一に粉砕混合して水和剤を得た。 [Example 3]
<Formulation example 3>
2. 50.0 parts of the compound represented by the formula (2), 4.0 parts of dialkylsulfosuccinate, 3.0 parts of polyoxyethylene alkyl ether, salt of formalin condensate (formaldehyde condensate) of alkylnaphthalenesulfonic acid 0 parts, 39.5 parts of kaolin, 0.5 parts of a silicone-based antifoaming agent, and the above were ground and mixed uniformly to obtain a wettable powder.
［実施例４］
＜製剤例４＞
　式（２）で表される化合物５０．０部、アルキルナフタレンスルホン酸塩５．０部、リグニンスルホン酸塩３．０部、カオリン３６．５部、ホワイトカーボン５．０部、シリコーン系消泡剤０．５部、以上を均一に粉砕混合して水和剤を得た。 [Example 4]
<Formulation example 4>
50.0 parts of the compound represented by formula (2), 5.0 parts of alkylnaphthalene sulfonate, 3.0 parts of lignin sulfonate, 36.5 parts of kaolin, 5.0 parts of white carbon, silicone-based defoaming 0.5 parts of the agent was uniformly ground and mixed to obtain a wettable powder.
［実施例５］
＜製剤例５＞
　式（２）で表される化合物５０．０部、ポリオキシエチレントリスチリルフェニルエーテル硫酸アンモニウム塩（エチレンオキサイド付加モル数１４）１．８部、ポリオキシエチレンポリオキシプロピレンブロックコポリマー１．２部、プロピレングリコール５．０部、シリコーン系消泡剤０．５部、ベントナイト０．１部、水４１．４部、以上を均一に混合し、湿式粉砕してフロアブル剤を得た。 [Example 5]
<Formulation example 5>
50.0 parts of the compound represented by the formula (2), 1.8 parts of polyoxyethylene tristyryl phenyl ether ammonium sulfate (ethylene oxide addition mole number 14), 1.2 parts of polyoxyethylene polyoxypropylene block copolymer, propylene A flowable agent was obtained by uniformly mixing 5.0 parts of glycol, 0.5 parts of a silicone-based antifoaming agent, 0.1 part of bentonite and 41.4 parts of water and wet pulverizing them.
［実施例６］
＜製剤例６＞
　調製例１で得たブロフラニリドスラリー１０．０部、ポリオキシエチレントリスチリルフェニルエーテル硫酸アンモニウム塩（エチレンオキサイド付加モル数１４）３．０部、アルキルナフタレンスルホン酸のホルマリン縮合物（ホルムアルデヒド縮合物）の塩５．０部、調製例２で得た増粘剤溶液Ａ６０．０部および水２２．０部、以上を均一に混合してフロアブル剤を得た。 [Example 6]
<Formulation example 6>
10.0 parts of brofuranilide slurry obtained in Preparation Example 1, 3.0 parts of polyoxyethylene tristyryl phenyl ether ammonium sulfate (ethylene oxide addition mol number 14), formalin condensate (formaldehyde condensate) of alkylnaphthalene sulfonic acid A flowable agent was obtained by uniformly mixing 5.0 parts of the above salt, 60.0 parts of the thickener solution A obtained in Preparation Example 2, and 22.0 parts of water.
［実施例７］
＜製剤例７＞
　実施例６において、アルキルナフタレンスルホン酸のホルマリン縮合物（ホルムアルデヒド縮合物）の塩５．０部を１０．０部に変え、水２２．０部を１７．０部に変えた以外は実施例６と同様にしてフロアブル剤を得た。 [Example 7]
<Formulation example 7>
Example 6 In Example 6, except that 5.0 parts of salt of formalin condensate (formaldehyde condensate) of alkylnaphthalenesulfonic acid was changed to 10.0 parts and 22.0 parts of water were changed to 17.0 parts. In the same manner as above, a flowable agent was obtained.
［実施例８］
＜製剤例８＞
　実施例７において、ポリオキシエチレントリスチリルフェニルエーテル硫酸アンモニウム塩（エチレンオキサイド付加モル数１４）３．０部を５．０部に変え、水１７．０部を１５．０部に変えた以外は実施例７と同様にしてフロアブル剤を得た。 [Example 8]
<Formulation example 8>
In Example 7, except that 3.0 parts of polyoxyethylene tristyrylphenyl ether ammonium sulfate salt (ethylene oxide addition mole number 14) was changed to 5.0 parts, and 17.0 parts of water was changed to 15.0 parts. A flowable agent was obtained in the same manner as in Example 7.
［実施例９］
＜製剤例９＞
　実施例６において、ポリオキシエチレントリスチリルフェニルエーテル硫酸アンモニウム塩（エチレンオキサイド付加モル数１４）をポリオキシエチレントリスチリルフェニルエーテル硫酸アンモニウム塩（エチレンオキサイド付加モル数９）に変えた以外は実施例６と同様にしてフロアブル剤を得た。 [Example 9]
<Formulation example 9>
Example 6 is the same as Example 6 except that polyoxyethylene tristyryl phenyl ether sulfate ammonium salt (ethylene oxide addition mole number 14) is changed to polyoxyethylene tristyryl phenyl ether ammonium sulfate salt (ethylene oxide addition mole number 9). The flowable agent was obtained.
［実施例１０］
＜製剤例１０＞
　ブロフラニリドスラリー４０．０部、ポリオキシエチレントリスチリルフェニルエーテル硫酸アンモニウム塩（エチレンオキサイド付加モル数１４）３．０部、アルキルナフタレンスルホン酸のホルマリン縮合物（ホルムアルデヒド縮合物）の塩５．０部、調製例３で得た増粘剤溶液Ｂ４０．０部および水１２．０部を混合してフロアブル剤を得た。 [Example 10]
<Formulation Example 10>
40.0 parts of brofuranilide slurry, 3.0 parts of polyoxyethylene tristyryl phenyl ether ammonium sulfate (ethylene oxide addition mole number 14), 5.0 parts of formalin condensate (formaldehyde condensate) of alkylnaphthalene sulfonic acid The flowable agent was obtained by mixing 40.0 parts of the thickener solution B obtained in Preparation Example 3 and 12.0 parts of water.
［実施例１１］
＜製剤例１１＞
　実施例６において、ポリオキシエチレントリスチリルフェニルエーテル硫酸アンモニウム塩（エチレンオキサイド付加モル数１４）をポリオキシエチレントリスチリルフェニルエーテル硫酸アンモニウム塩（エチレンオキサイド付加モル数１６）に変えた以外は実施例６と同様にしてフロアブル剤を得た。 [Example 11]
<Formulation Example 11>
Example 6 is the same as Example 6 except that polyoxyethylene tristyryl phenyl ether sulfate ammonium salt (ethylene oxide addition mole number 14) is changed to polyoxyethylene tristyryl phenyl ether ammonium sulfate salt (ethylene oxide addition mole number 16). The flowable agent was obtained.
　次に、本実施形態に係る組成物および吸血性節足動物防除方法の有用性について、以下の試験例において具体的に説明するが、本発明はこれらのみに限定されるものではない。 Next, the usefulness of the composition and blood-sucking arthropod control method according to the present embodiment will be specifically described in the following test examples, but the present invention is not limited to these.
＜試験例１＞
　ガンビエハマダラカ（Ａｎｏｐｈｅｌｅｓ　ｇａｍｂｉａｅ）に対する、種々の壁面材質を用いた室内残留散布（ＩＲＳ：ｉｎｄｏｏｒ　ｒｅｓｉｄｕａｌ　ｓｐｒａｙｉｎｇ）試験
供試薬剤：製剤例２に準じて調製した水和剤（実施例２）、Bendiocarb　WP（参考例１）
壁面材質：Ｗｏｏｄ，Ｔｉｌｅ，Ｃｅｍｅｎｔ
供試虫　：ガンビエハマダラカ（Ａｎｏｐｈｅｌｅｓ　ｇａｍｂｉａｅ）Ｋｉｓｕｍｕ系統
処理方法：１０月に上記製剤の希釈液を所定薬量になるようタワー散布機にて上記壁面材質に散布し、乾燥させた後に温度３０℃、湿度８０％の恒温室内に保管した。
殺虫試験：上記処理された壁面材質の上にスタンダードＷＨＯプラスチックコーンをかぶせ、ガンビエハマダラカ雌成虫を入れ蓋をした。３分暴露させた後にガンビエハマダラカを別の容器に入れ、さらに２４時間後に生死を調査し死虫率を算出した。これを１１月～翌４月まで継続し、残効性を評価した（３連制）。 <Test Example 1>
Indoor residual spraying (IRS) using various wall materials for Anopheles gambiae Reagent: A wettable powder prepared according to Formulation Example 2 (Example 2), Bendiocarb WP (Reference Example 1)
Wall material: Wood, Tile, Cement
Test insects: Anopheles gambiae Kisumu system treatment method: In October, a diluted solution of the above formulation is sprayed on the wall surface material with a tower sprayer so as to have a predetermined dose, and then dried at a temperature of 30 ° C. And stored in a constant temperature room with a humidity of 80%.
Insecticidal test: A standard WHO plastic cone was placed on the treated wall surface material, and a female Gambier anopheles female adult was placed on the lid. After exposure for 3 minutes, Gambier anopheles was placed in a separate container, and after 24 hours, life and death were examined to calculate the mortality. This was continued from November to the following April, and the residual effect was evaluated (three consecutive systems).
　結果を表１に示す。 The results are shown in Table 1.
Figure JPOXMLDOC01-appb-T000007
Figure JPOXMLDOC01-appb-T000007
＜試験例２＞
　チカイエカ（Ｃｕｌｅｘ　ｐｉｐｉｅｎｓ　ｍｏｌｅｓｔｕｓ）に対する残効性試験
供試製剤：製剤例６に準じて調製したフロアブル剤（実施例６）、ICON 10CS（参考例２、対照剤　Lambda-cyhalothrin）
壁面材質：化粧合板、ベニヤ板、セメント、日干し煉瓦
供試虫　：チカイエカ（Ｃｕｌｅｘ　ｐｉｐｉｅｎｓ　ｍｏｌｅｓｔｕｓ）
処理方法：上記製剤の希釈液７ｍｌをタワー散布機にて上記壁面材質に散布し乾燥させた後に温度２５℃、湿度６０％の恒温室内に保管した。
殺虫試験：壁面材質にプラスチックカップをかぶせ、中にチカイエカ雌成虫を入れ蓋をした。３０分暴露させた後にチカイエカを別のプラスチックカップに入れ、さらに２４時間後に生死を調査し死虫率を算出した（２連制）。 <Test Example 2>
Residual efficacy test sample preparation for Cika pipiens molestus: flowable agent prepared according to Formulation Example 6 (Example 6), ICON 10CS (Reference Example 2, control agent Lambda-cyhalothrin)
Wall material: decorative plywood, plywood, cement, sun-dried brick test insect: Chilex epien (Culex pipiens molestus)
Treatment method: 7 ml of the diluted solution of the preparation was sprayed on the wall surface material with a tower sprayer and dried, and then stored in a temperature-controlled room at a temperature of 25 ° C. and a humidity of 60%.
Insecticidal test: A plastic cup was put on the wall material, and a female Chikaieka female was placed inside and covered. After 30 minutes of exposure, Chikaeka was placed in another plastic cup, and after 24 hours, life and death were investigated and the death rate was calculated (two-line system).
　結果を表２に示す。 The results are shown in Table 2.
Figure JPOXMLDOC01-appb-T000008
Figure JPOXMLDOC01-appb-T000008
＜試験例３＞
　ガンビエハマダラカ（Ａｎｏｐｈｅｌｅｓ　ｇａｍｂｉａｅ）に対する蚊帳浸漬試験
供試製剤：製剤例５に準じて調製したフロアブル剤（実施例５）、PermaNet２（参考例３、Deltamethrin）
供試虫　：ガンビエハマダラカ（Ａｎｏｐｈｅｌｅｓ　ｇａｍｂｉａｅ）Ｋｉｓｕｍｕ系統
処理方法：上記製剤の希釈液にポリエステルネットを浸漬し、乾燥させた。
殺虫試験：上記ネットにスタンダードＷＨＯプラスチックコーンをかぶせ中にガンビエハマダラカ雌成虫を放虫し３分間または２０分間暴露させた後に別の容器に入れ、１、２４、４８、７２時間後にノックダウン（KD）数を調査しKD率を算出した（３連制）。 <Test Example 3>
Test preparation for mosquito net immersion test for Anopheles gambiae: flowable agent prepared in accordance with Formulation Example 5 (Example 5), PermaNet2 (Reference Example 3, Deltamethrin)
Test insect: Anopheles gambiae Kisumu system treatment method: A polyester net was immersed in a diluted solution of the above preparation and dried.
Insecticidal test: The above-mentioned net is covered with a standard WHO plastic cone, and adult female Gambier spp. Is exposed to 3 minutes or 20 minutes, then placed in another container and knocked down after 1, 24, 48, 72 hours ( The number of KD) was investigated and the KD rate was calculated (triple system).
　結果を表３に示す。 The results are shown in Table 3.
Figure JPOXMLDOC01-appb-T000009
Figure JPOXMLDOC01-appb-T000009
＜試験例４＞
　抵抗性ガンビエハマダラカ（Ａｎｏｐｈｅｌｅｓ　ｇａｍｂｉａｅ）に対する室内残留散布（ＩＲＳ：ｉｎｄｏｏｒ　ｒｅｓｉｄｕａｌ　ｓｐｒａｙｉｎｇ）試験
供試薬剤：製剤例２に準じて調製した水和剤（実施例２）、Bendiocarb　WP（参考例１）、Deltamethrin　WG（参考例４）
壁面材質：Ｗｏｏｄ
供試虫　：ガンビエハマダラカ（Ａｎｏｐｈｅｌｅｓ　ｇａｍｂｉａｅ）Ｋｉｓｕｍｕ系統およびＴｉａｓｓａｌｅ２系統
処理方法：上記製剤の希釈液を所定薬量になるようタワー散布機にて上記壁面材質に散布し、乾燥させた。
殺虫試験：上記処理された壁面材質の上にスタンダードＷＨＯプラスチックコーンをかぶせ、ガンビエハマダラカ雌成虫を入れ蓋をした。３分暴露させた後にガンビエハマダラカを別の容器に入れた。さらに１、２４、４８、７２時間後にノックダウン（KD）数を調査しKD率を算出した（３連制）。 <Test Example 4>
Residual spraying (IRS: indoor residual spraying) for resistant gambiae arabes (Anopheles gambiae): Reagents prepared according to Formulation Example 2 (Example 2), Bendiocarb WP (Reference Example 1), Deltamethrin WG (Reference Example 4)
Wall material: Wood
Test insect: Anopheles gambiae Kisumu line and Tiassale 2 line Treatment method: The diluted solution of the above preparation was sprayed on the wall surface material with a tower sprayer so as to have a predetermined dose, and dried.
Insecticidal test: A standard WHO plastic cone was placed on the treated wall surface material, and a female Gambier anopheles female adult was placed on the lid. After exposure for 3 minutes, Gambier anopheles was placed in a separate container. Further, after 1, 24, 48, and 72 hours, the number of knockdowns (KD) was investigated and the KD rate was calculated (three consecutive systems).
　結果を表４に示す。 The results are shown in Table 4.
Figure JPOXMLDOC01-appb-T000010
Figure JPOXMLDOC01-appb-T000010
＜試験例５＞
　交差抵抗試験（ｉ）ガンビエハマダラカ（Ａｎｏｐｈｅｌｅｓ　ｇａｍｂｉａｅ）およびネッタイシマカ（Ａｅｄｅｓ　ａｅｇｙｐｔｉ）各系統に対する感受性検定
供試薬剤：式（２）で表される化合物
供試虫　：ガンビエハマダラカ（Ａｎｏｐｈｅｌｅｓ　ｇａｍｂｉａｅ）Ｋｉｓｕｍｕ系統、Ｋｉｓｕｍｕ　ＲＤＬ系統、Ａｋｒｏｎ系統、Ｔｉａｓｓａｌｅ２系統およびネッタイシマカ（Ａｅｄｅｓ　ａｅｇｙｐｔｉ）Ｃａｙｍａｎ系統、Ｎｅｗ　Ｏｒｌｅａｎｓ系統
殺虫試験：式（２）で表される化合物をアセトンで所定濃度に希釈し局所施用装置を用いて対象昆虫雌成虫の胸部に施用した。２４時間後死虫率を調査した。 <Test Example 5>
Cross resistance test (i) Sensitivity test reagent for each strain of Abiepheus gambiae and Aedes aegypti: Compound test insect represented by formula (2): Abiepheus gambiae strain , Kisumu RDL line, Akron line, Tiassale 2 line, Aedes aegypti Cayman line, New Orleans line insecticidal test: The compound represented by formula (2) is diluted to a predetermined concentration with acetone, and the target insect is used using a local application device. Applied to adult female breast. After 24 hours, the death rate was investigated.
　結果を表５に示す。 The results are shown in Table 5.
Figure JPOXMLDOC01-appb-T000011
Figure JPOXMLDOC01-appb-T000011
　　　　　＜試験例６＞
　シナハマダラカ（Ａｎｏｐｈｅｌｅｓ　ｓｉｎｅｎｓｉｓ）に対する感受性検定
供試薬剤：式（２）で表される化合物
供試虫　：シナハマダラカ（Ａｎｏｐｈｅｌｅｓ　ｓｉｎｅｎｓｉｓ）２０１６年８月滋賀県採集系統
殺虫試験：式（２）で表される化合物をアセトンで所定濃度に希釈し局所施用装置を用いて対象昆虫雌成虫の胸部に０．２μｌ／頭を施用した。１、２４、４８および７２時間後にノックダウン（KD）数を調査しKD率を算出した（３連制）。 <Test Example 6>
Sensitivity test reagent for Anopheles sinensis: Compound represented by formula (2) Test specimen: Anopheles sinensis August 2016 Shiga Prefecture collected line insecticide test: compound represented by formula (2) Was diluted to a predetermined concentration with acetone, and 0.2 μl / head was applied to the chest of a female target insect using a local application device. After 1, 24, 48 and 72 hours, the number of knockdowns (KD) was investigated and the KD rate was calculated (triple regime).
　結果を表６に示す。 The results are shown in Table 6.
Figure JPOXMLDOC01-appb-T000012
Figure JPOXMLDOC01-appb-T000012
＜試験例７＞
　ガンビエハマダラカ（Ａｎｏｐｈｅｌｅｓ　ｇａｍｂｉａｅ）に対する室内残留散布（ＩＲＳ：ｉｎｄｏｏｒ　ｒｅｓｉｄｕａｌ　ｓｐｒａｙｉｎｇ）試験
供試薬剤：製剤例３に準じて調製した水和剤（実施例３）、Bendiocarb　WP（参考例１）、Deltamethrin　WG（参考例４）
壁面材質：Ｍｕｄ
供試虫　：ガンビエハマダラカ（Ａｎｏｐｈｅｌｅｓ　ｇａｍｂｉａｅ）Ｋｉｓｕｍｕ系統
処理方法：４月に上記製剤の希釈液を所定薬量になるようタワー散布機にて上記壁面材質に散布し、乾燥させた後に温度３０℃、湿度８０％の恒温室内に保管した。
殺虫試験：上記処理された壁面材質の上にスタンダードＷＨＯプラスチックコーンをかぶせ、ガンビエハマダラカ雌成虫を入れ蓋をした。３分暴露させた後にガンビエハマダラカを別の容器に入れ、更に２４時間後に生死を調査し死虫率を算出した。これを５月～１１月まで継続し、残効性を評価した（３連制）。 <Test Example 7>
Indoor Residual Spraying (IRS) test agent for Anopheles gambiae: wettable powder prepared according to Formulation Example 3 (Example 3), Bendiocarb WP (Reference Example 1), Deltamethrin WG (Reference Example 4)
Wall material: Mud
Test insects: Anopheles gambiae Kisumu system treatment method: In April, a diluted solution of the above preparation is sprayed on the wall surface material with a tower sprayer so as to have a predetermined amount, and then dried at a temperature of 30 ° C. And stored in a constant temperature room with a humidity of 80%.
Insecticidal test: A standard WHO plastic cone was placed on the treated wall surface material, and a female Gambier anopheles female adult was placed on the lid. After exposure for 3 minutes, Gambier anopheles was placed in a separate container, and after 24 hours, life and death were investigated to calculate the mortality. This was continued from May to November, and the residual effect was evaluated (three consecutive systems).
　結果を表７に示す。 The results are shown in Table 7.
Figure JPOXMLDOC01-appb-T000013
Figure JPOXMLDOC01-appb-T000013
＜試験例８＞
　チカイエカ（Ｃｕｌｅｘ　ｐｉｐｉｅｎｓ　ｍｏｌｅｓｔｕｓ）幼虫に対する殺虫試験
供試薬剤：式（２）で表される化合物
供試虫　：チカイエカ（Ｃｕｌｅｘ　ｐｉｐｉｅｎｓ　ｍｏｌｅｓｔｕｓ）
殺虫試験：ガラス管に２５ｍｌの水を入れ、次いで、式（２）で表される化合物のアセトン溶液２５０μｌを加え所定濃度に調製した。終齢幼虫１０頭を放試し、２日後に生死を調査し死虫率を算出した。
　結果、式（２）で表される化合物は０．００１ｐｐｍで７０％以上の死虫率を示した。 <Test Example 8>
Insecticidal test reagent for larvae of Culex pipiens molestus: Compound test worm represented by formula (2): tiger squid (Culex pipiens molestus)
Insecticidal test: 25 ml of water was put into a glass tube, and then 250 μl of an acetone solution of the compound represented by the formula (2) was added to prepare a predetermined concentration. Ten final-age larvae were released, and after 2 days, life and death were investigated, and the mortality rate was calculated.
As a result, the compound represented by the formula (2) showed a death rate of 70% or more at 0.001 ppm.
＜試験例９＞
　ガンビエハマダラカ（Ａｎｏｐｈｅｌｅｓ　ｇａｍｂｉａｅ）に対する蚊帳浸漬試験
供試組成物：以下の表８に示す組成物１～組成物８
供試虫　：ガンビエハマダラカ（Ａｎｏｐｈｅｌｅｓ　ｇａｍｂｉａｅ）Ｋｉｓｕｍｕ系統およびピレスロイド抵抗性系統
処理方法：上記組成物の希釈液にポリエステルネットを浸漬し、乾燥させた。
殺虫試験：上記ネットにスタンダードＷＨＯプラスチックコーンをかぶせ中にガンビエハマダラカ雌成虫を放虫し３分間または２０分間暴露させた後に別の容器に入れ、１、２４、４８、７２時間後にノックダウン（KD）数を調査しKD率を算出した（３連制）。 <Test Example 9>
Mosquito net soaking test test composition against Gambier gamabiae: Composition 1 to Composition 8 shown in Table 8 below
Test insect: Anopheles gambiae Kisumu strain and pyrethroid resistant strain Treatment method: Polyester net was immersed in a diluted solution of the above composition and dried.
Insecticidal test: The above-mentioned net is covered with a standard WHO plastic cone, and adult female Gambier spp. Is exposed to 3 minutes or 20 minutes, then placed in another container and knocked down after 1, 24, 48, 72 hours ( The number of KD) was investigated and the KD rate was calculated (triple system).
Figure JPOXMLDOC01-appb-T000014
Figure JPOXMLDOC01-appb-T000014
　試験例９では、混合組成物（表８中の組成物６～９）を処理した蚊帳は、コントロール（表８中の組成物１～５）に対して、優位に高い殺虫効果を示した。 In Test Example 9, mosquito nets treated with the mixed composition (Compositions 6 to 9 in Table 8) showed a significantly higher insecticidal effect than the control (Compositions 1 to 5 in Table 8).
　２０１６年１月１２日に出願された日本国特許出願２０１６－００３６５７の開示はその全体が参照により本明細書に取り込まれる。
　本明細書に記載された全ての文献、特許出願、および技術規格は、個々の文献、特許出願、および技術規格が参照により取り込まれることが具体的かつ個々に記された場合と同程度に、本明細書中に参照により取り込まれる。 The disclosure of Japanese Patent Application No. 2016-003657 filed on Jan. 12, 2016 is incorporated herein by reference in its entirety.
All documents, patent applications, and technical standards mentioned in this specification are to the same extent as if each individual document, patent application, and technical standard were specifically and individually described to be incorporated by reference, Incorporated herein by reference.
　本実施形態に係る組成物は長期残効性を有し、かつ抵抗性害虫にも有効であることから、産業上の利用可能性が高い。 The composition according to the present embodiment has a long-term residual effect and is also effective against resistant pests, and therefore has high industrial applicability.

Claims (19)

  1. 　下記一般式（１）
    Figure JPOXMLDOC01-appb-C000001
    （式中、Ｑはフェニル基またはフッ素原子で置換されたフェニル基を表す。Ｒは水素原子またはメチル基を表す。Ｙ１およびＹ２はそれぞれ独立に、臭素原子、ヨウ素原子またはトリフルオロメチル基を表す。）で表されるアミド誘導体の少なくとも１種を有効成分として含有する居住空間形成物処理用吸血性節足動物防除組成物によって、居住空間形成物を処理する吸血性節足動物防除方法。     The following general formula (1)
    Figure JPOXMLDOC01-appb-C000001
    (In the formula, Q represents a phenyl group or a phenyl group substituted with a fluorine atom. R represents a hydrogen atom or a methyl group. Y 1 and Y 2 are each independently a bromine atom, an iodine atom or a trifluoromethyl group. The blood-sucking arthropod control method which treats a living space formation with the blood-sucking arthropod control composition for living space formation processing which contains at least 1 sort (s) of the amide derivative represented by this as an active ingredient .
  2. 　前記一般式（１）で表されるアミド誘導体が、２－フルオロ－３－（Ｎ－メチルベンズアミド）－Ｎ－（２－ブロモ－６－トリフルオロメチル－４－（ヘプタフルオロプロパン－２－イル）フェニル）ベンズアミドである請求項１に記載の吸血性節足動物防除方法。 The amide derivative represented by the general formula (1) is 2-fluoro-3- (N-methylbenzamide) -N- (2-bromo-6-trifluoromethyl-4- (heptafluoropropan-2-yl). 2. The method for controlling blood-sucking arthropods according to claim 1, which is phenyl) benzamide.
  3. 　前記居住空間形成物が家屋壁面または蚊帳である、請求項１または請求項２に記載の吸血性節足動物防除方法。 The blood-sucking arthropod control method according to claim 1 or 2, wherein the living space formation is a house wall surface or a mosquito net.
  4. 　前記居住空間形成物を処理する方法が散布または浸漬処理である、請求項１～請求項３のいずれか１項に記載の吸血性節足動物防除方法。 The blood-sucking arthropod control method according to any one of claims 1 to 3, wherein the method for treating the living space formation is a spraying or dipping treatment.
  5. 　防除される吸血性節足動物が、ハエ目（Ｄｉｐｔｅｒａ）カ科（Ｃｕｌｉｃｉｄａｅ）であるＡｎｏｐｈｅｌｅｓ属昆虫、Ａｅｄｅｓ属昆虫およびＣｕｌｅｘ属昆虫からなる群より選択される少なくとも１種である、請求項１～請求項４のいずれか１項に記載の吸血性節足動物防除方法。 The blood-sucking arthropod to be controlled is at least one selected from the group consisting of the genus Anopheles, the genus Aedes, and the genus Culex, which are Diptera family Clicidae The blood-sucking arthropod control method of any one of Claim 4.
  6. 　前記ハエ目（Ｄｉｐｔｅｒａ）カ科（Ｃｕｌｉｃｉｄａｅ）昆虫が、Ａｎｏｐｈｅｌｅｓ属昆虫である、請求項５に記載の吸血性節足動物防除方法。 The method for controlling blood-sucking arthropods according to claim 5, wherein the Dipteridae (Clicidae) insect is an Anopheles insect.
  7. 　前記Ａｎｏｐｈｅｌｅｓ属昆虫が、ガンビエハマダラカ（Ａｎｏｐｈｅｌｅｓ　ｇａｍｂｉａｅ）およびシナハマダラカ（Ａｎｏｐｈｅｌｅｓ　ｓｉｎｅｎｓｉｓ）の少なくとも一方である、請求項５または請求項６に記載の吸血性節足動物防除方法。 The method for controlling a blood-sucking arthropod according to claim 5 or 6, wherein the Anopheles genus insect is at least one of Gambier gambiae and Anopheles sinensis.
  8. 　前記居住空間形成物処理用吸血性節足動物防除組成物は、ペルメトリン、アルファシペルメトリン、デルタメトリンおよびエトフェンプロックスからなる群より選択される少なくとも１種の化合物を更なる有効成分として含有する、請求項１～請求項７のいずれか１項に記載の吸血性節足動物防除方法。 The blood-sucking arthropod control composition for treating living space formations contains at least one compound selected from the group consisting of permethrin, alpha cypermethrin, deltamethrin and etofenprox as a further active ingredient. The method for controlling blood-sucking arthropods according to any one of claims 1 to 7.
  9. 　前記居住空間形成物処理用吸血性節足動物防除組成物は水和剤又はフロアブル剤である、請求項１～請求項８のいずれか１項に記載の吸血性節足動物防除方法。 The blood-sucking arthropod control method according to any one of claims 1 to 8, wherein the blood-sucking arthropod control composition for treating living space formation is a wettable powder or a flowable agent.
  10. 　請求項１～請求項９のいずれか１項に記載の吸血性節足動物防除方法に使用される吸血性節足動物防除組成物。 A blood-sucking arthropod control composition used in the blood-sucking arthropod control method according to any one of claims 1 to 9.
  11. 　居住空間形成物処理用である、請求項１０に記載の吸血性節足動物防除組成物。 The composition for controlling blood-sucking arthropods according to claim 10, which is used for treating living space formations.
  12. 　下記一般式（１）
    Figure JPOXMLDOC01-appb-C000002
     
    （式中、Ｑはフェニル基またはフッ素原子で置換されたフェニル基を表す。Ｒは水素原子またはメチル基を表す。Ｙ１およびＹ２はそれぞれ独立に、臭素原子、ヨウ素原子またはトリフルオロメチル基を表す。）で表されるアミド誘導体の少なくとも１種を有効成分として含有する、居住空間形成物処理用吸血性節足動物防除組成物。     The following general formula (1)
    Figure JPOXMLDOC01-appb-C000002

    (In the formula, Q represents a phenyl group or a phenyl group substituted with a fluorine atom. R represents a hydrogen atom or a methyl group. Y 1 and Y 2 are each independently a bromine atom, an iodine atom or a trifluoromethyl group. A blood-sucking arthropod control composition for treating living space formations, which contains at least one amide derivative represented by the formula:
  13. 　前記一般式（１）で表されるアミド誘導体が、２－フルオロ－３－（Ｎ－メチルベンズアミド）－Ｎ－（２－ブロモ－６－トリフルオロメチル－４－（ヘプタフルオロプロパン－２－イル）フェニル）ベンズアミドである請求項１２に記載の居住空間形成物処理用吸血性節足動物防除組成物。 The amide derivative represented by the general formula (1) is 2-fluoro-3- (N-methylbenzamide) -N- (2-bromo-6-trifluoromethyl-4- (heptafluoropropan-2-yl). 13. The blood-sucking arthropod control composition for treating living space formations according to claim 12, which is phenyl) benzamide.
  14. 　居住空間形成物としての家屋壁面または蚊帳の処理に用いられる、請求項１２または請求項１３に記載の居住空間形成物処理用吸血性節足動物防除組成物。 The blood-sucking arthropod control composition for living space formation processing of Claim 12 or Claim 13 used for the process of the house wall surface or mosquito net as a living space formation.
  15. 　吸血性節足動物としてのハエ目（Ｄｉｐｔｅｒａ）カ科（Ｃｕｌｉｃｉｄａｅ）であるＡｎｏｐｈｅｌｅｓ属昆虫、Ａｅｄｅｓ属昆虫およびＣｕｌｅｘ属昆虫からなる群より選択される少なくとも１種の防除に用いられる、請求項１２～請求項１４のいずれか１項に記載の居住空間形成物処理用吸血性節足動物防除組成物。 It is used for the control of at least one species selected from the group consisting of Anopheles insects, Aedes insects and Culex insects which are Dipteridae (Clicidae) as a blood-sucking arthropod. The blood-sucking arthropod control composition for living space formation processing of any one of Claim 14.
  16. 　前記ハエ目（Ｄｉｐｔｅｒａ）カ科（Ｃｕｌｉｃｉｄａｅ）昆虫が、Ａｎｏｐｈｅｌｅｓ属昆虫である、請求項１５に記載の居住空間形成物処理用吸血性節足動物防除組成物。 The blood-sucking arthropod control composition for living space formation treatment according to claim 15, wherein the Dipteridae (Clicidae) insect is an Anopheles genus insect.
  17. 　前記Ａｎｏｐｈｅｌｅｓ属昆虫が、ガンビエハマダラカ（Ａｎｏｐｈｅｌｅｓ　ｇａｍｂｉａｅ）およびシナハマダラカ（Ａｎｏｐｈｅｌｅｓ　ｓｉｎｅｎｓｉｓ）の少なくとも一方である、請求項１５または請求項１６に記載の居住空間形成物処理用吸血性節足動物防除組成物。 The blood-sucking arthropod control composition for living space formation treatment according to claim 15 or 16, wherein the Anopheles genus insect is at least one of Gambier gambiae and Anopheles sinensis.
  18. 　ペルメトリン、アルファシペルメトリン、デルタメトリンおよびエトフェンプロックスからなる群より選択される少なくとも１種の化合物を更なる有効成分として含有する、請求項１２～請求項１７のいずれか１項に記載の居住空間形成物処理用吸血性節足動物防除組成物。 The living space formation according to any one of claims 12 to 17, further comprising at least one compound selected from the group consisting of permethrin, alpha cypermethrin, deltamethrin and etofenprox as a further active ingredient. A blood-sucking arthropod control composition for physical treatment.
  19. 　水和剤又はフロアブル剤である、請求項１２～請求項１８のいずれか１項に記載の居住空間形成物処理用吸血性節足動物防除組成物。 The blood-sucking arthropod control composition for living space formation treatment according to any one of claims 12 to 18, which is a wettable powder or a flowable agent.
PCT/JP2017/000655 2016-01-12 2017-01-11 Blood-sucking-arthropod control method and blood-sucking-arthropod control composition for treating elements that form living spaces WO2017122687A1 (en)

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