WO2017071450A1 - 转盘式便隐血检测分析仪 - Google Patents
转盘式便隐血检测分析仪 Download PDFInfo
- Publication number
- WO2017071450A1 WO2017071450A1 PCT/CN2016/100781 CN2016100781W WO2017071450A1 WO 2017071450 A1 WO2017071450 A1 WO 2017071450A1 CN 2016100781 W CN2016100781 W CN 2016100781W WO 2017071450 A1 WO2017071450 A1 WO 2017071450A1
- Authority
- WO
- WIPO (PCT)
- Prior art keywords
- sample
- cartridge holder
- occult blood
- sample cartridge
- carousel
- Prior art date
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Classifications
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- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N35/00—Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor
- G01N35/02—Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor using a plurality of sample containers moved by a conveyor system past one or more treatment or analysis stations
- G01N35/025—Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor using a plurality of sample containers moved by a conveyor system past one or more treatment or analysis stations having a carousel or turntable for reaction cells or cuvettes
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- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/483—Physical analysis of biological material
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N35/00—Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor
- G01N35/00584—Control arrangements for automatic analysers
- G01N35/00722—Communications; Identification
- G01N35/00732—Identification of carriers, materials or components in automatic analysers
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- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N35/00—Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor
- G01N35/02—Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor using a plurality of sample containers moved by a conveyor system past one or more treatment or analysis stations
- G01N35/04—Details of the conveyor system
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N35/00—Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor
- G01N35/00584—Control arrangements for automatic analysers
- G01N35/00722—Communications; Identification
- G01N35/00732—Identification of carriers, materials or components in automatic analysers
- G01N2035/00742—Type of codes
- G01N2035/00752—Type of codes bar codes
Definitions
- the invention claims that the Chinese patent invention name is: a rotary occult blood detection analyzer, and the application number is: CN2015107260358.
- the invention relates to the field of medical detection, in particular to a rotary occult blood detection analyzer.
- occult blood refers to the occult blood in the stool, referred to as occult blood, that is, a small amount of gastrointestinal bleeding, usually does not cause changes in stool color, red blood cells are digested and destroyed, no abnormal changes in the appearance of the stool, the naked eye and the microscope No bleeding can be confirmed under the test. Only when the stool is examined, there is a small amount of blood cells in the stool. Due to a small amount of bleeding for a long time, symptoms of anemia are often accompanied. Because the occult blood can not be directly detected by the naked eye, most patients with early malignant tumors of the digestive tract can not find and early intervention, thus delaying the best time for treatment, like hidden killers lurking in people's bodies.
- CN 103543285A discloses an automatic occult blood detecting device for detecting a sample box, the sample box comprising a transparent sleeve and a toilet bowl and a test strip placed in the transparent sleeve, the detecting device comprising: a feeding channel and a sending channel The two are arranged side by side, respectively for separately transmitting the sample box, the transfer platform, between the feeding channel and the sending channel, and the push rod for pushing the sample box on the feeding channel to the sending channel via the transfer platform And an image acquisition device disposed on one side of the delivery channel, wherein the image acquisition device is configured to acquire the ribbon information presented on the test strip.
- the occult blood automatic detection device has at least the following problems:
- the feeding channel and the sending channel are arranged side by side, which increases the occupied space of the device.
- the invention provides a rotary occult blood detection analyzer to solve the problem that the existing occult blood automatic detecting device occupies a large space.
- the present invention provides a rotary occult blood detection analyzer for detecting a sample cartridge, and the rotary occult blood detection analyzer includes:
- sample cassette holder carrying a plurality of sample cartridges, the sample cartridge holder being disc-shaped;
- a driving device that drives the sample cartridge holder to rotate
- the information collecting device collects the ribbon information presented on the test strip in the sample box and the label information on the sample box.
- the sample cartridge holder can be rotated 360°, and the bottom of the sample cartridge holder is provided with a plurality of clamping slots for clamping or carrying the sample cartridge, and the side of the clamping slot is for the sample cartridge
- the front and back of the photo and the scanning window open the window.
- the driving device comprises: a sample cartridge holder driving motor, a gear set connected to the sample cartridge holder driving motor, and a main shaft connected to the gear set, the sample cartridge holder being coupled to the main shaft.
- the pressing device includes: a bracket, a push-down driving motor disposed on the bracket, a lower pressing rod driven by the pressing driving motor, and a hinged upper pressing rod on the bracket Hinge shaft.
- the information collecting device includes: a scanner installed inside the sample cartridge holder, and a camera disposed outside the sample cartridge holder, a connection between the scanner and the camera, and the The radial direction of the sample holder is the same.
- the pressing device further includes: a first sensor that detects a position of the pressing lever.
- the driving device further includes: a second sensor that detects a position of the sample cartridge holder.
- sample cartridge holder is further provided with a third sensor that detects whether the sample cartridge has been loaded onto the sample cartridge holder.
- the carousel occult blood detection analyzer comprises: a bottom plate, and the sample cartridge holder, the driving device, the pressing device and the information collecting device are all disposed on the bottom plate.
- the carousel occult blood detecting analyzer further comprises: a control device connecting the driving device, the pressing device and the information collecting device.
- the invention adopts a disc-shaped sample box holder to carry a sample box, completes the transmission and detection of the sample box through the rotation of the sample box holder, and solves the problem that the chain type or the conveyor belt type adopts a large space and a large volume by the circumferential transmission method. . Therefore, the invention has the advantages of small size, compact structure, convenient carrying and moving, and increased detection flexibility.
- the invention realizes continuous detection of multiple sample boxes, precise positioning, no problem of overturning of the sample box, and can accurately press the sample box, react the sample diluent and the test strip, complete the detection, and realize the result output after the image is collected. .
- FIG. 1 is a schematic structural view of a rotary occult blood detecting analyzer according to an embodiment of the present invention, wherein a sample box is removed frame;
- FIG. 2 is a schematic perspective structural view of a front view direction of a rotary occult blood detecting analyzer according to an embodiment of the present invention, wherein a sample cartridge holder is installed;
- FIG. 3 is a view showing the structure of a sample cartridge holder according to an embodiment of the present invention.
- FIG. 4 is a structural diagram of a positioning disk according to an embodiment of the present invention.
- FIG. 5 is a schematic perspective structural view of a turntable type occult blood detecting analyzer according to an embodiment of the present invention.
- the rotary occult blood detection analyzer of the embodiment of the invention includes:
- a sample cassette holder 17 carrying a plurality of sample cartridges is mounted on the main shaft 3, as shown in FIG. 3, the sample cartridge holder 17 is disc-shaped, capable of 360° rotary motion, and a plurality of sample cartridge holders 17 are provided at the bottom.
- the clamping slot of the sample box 16 is clamped or carried, and the side of the clamping slot is a window for photographing and scanning the front and back of the sample box 16, and the sample cartridge holder 17 serves as a sample and test strip reaction and information.
- the sample rack 17 can be mounted on the main shaft through the support plate 40.
- the support plate 40 is sleeved on the main shaft.
- the support plate 40 is provided with a plurality of perforations for mounting the third sensor 4 and sweeping.
- the encoder 7 and the like, the support tray 40 supports the sample cartridge holder 17;
- a pressure plate 6 may also be disposed at the top of the sample cartridge holder 17.
- the pressure plate 6 reciprocates and rotates on the main shaft, and cooperates with the sample cartridge frame 17 through a specific geometric shape to realize axial positioning of the sample cartridge frame 17 on the main shaft 3;
- the pressure plate has a circular shape and is uniformly distributed at the outermost edge of the circular shape. a plurality of protruding flanges that cooperate with rectangular recesses on the sample cartridge holder to facilitate loading and unloading and positioning of the sample cartridge holder 17;
- a driving device that drives the sample cartridge holder 17 to rotate
- An information collecting device An information collecting device, ribbon information presented on a test strip in the sample cartridge, and label information on the sample cartridge (patient information on the sample cartridge).
- the driving device includes: a sample cartridge holder driving motor 1, a gear set connected to the sample cartridge holder driving motor, and a spindle connected to the gear set 3.
- the sample cartridge holder 17 is attached to the spindle 3.
- the gear set includes a large gear and a pinion that mesh with each other, the sample frame drive motor 1 drives a pinion gear, the pinion gear drives the large gear to rotate, and the rotating shaft of the large gear is a main shaft or a connecting main shaft, thereby driving the main shaft 3 to rotate, and driving the sample box frame 17 Turn.
- a positioning device 5, such as a positioning pin, is provided on the main shaft for mounting and positioning the sample cartridge holder 17 to ensure the stability of the rotation of the sample cartridge holder 17.
- the sample cassette holder 17 is finally operated at a predetermined speed by the large and small gear transmission, and the sample cartridge holder is rotated reliably, and the rotation speed is controllable, and the speed required for the detection is satisfied.
- the pressing device includes: a bracket 30, a push-down driving motor 10 disposed on the bracket, a pressing lever 9 driven by the driving motor, and A hinge shaft that articulates the lower pressing rod on the bracket.
- the lower driving motor 10 can be connected to a linkage 12 to drive the linkage to reciprocate, the linkage 12 to drive the lower pressing rod 9 to reciprocate, and the linkage 12 can be a slider.
- the information collecting device includes: a scanner 7 disposed inside the sample cartridge holder, and a camera 8 disposed outside the sample cartridge holder, and the scanner 7 is configured to collect patient information on the sample cartridge
- the camera 8 is used to collect the detection result (image or state of the test strip).
- the wire connecting the scanner and the camera is the same as the radial direction of the sample cartridge frame, so that the scanner 7 collects patient information on the sample cartridge inside the sample cartridge frame, and at the same time, the camera 8 is in the sample
- the detection result is collected outside the cassette holder, so that the scanning code and the photograph are simultaneously performed to speed up the detection.
- the pressing device further includes: a first sensor 11 for detecting the position of the pressing lever for detecting the pressing lever to realize positioning and resetting.
- the first sensor 11 is, for example, a photoelectric sensor, and the detection is rapid.
- the driving device further includes: a second sensor 13 for detecting the position of the sample cartridge holder for positioning when the sample cartridge holder 17 is rotated.
- the second sensor 13 is preferably a U-shaped sensor adapted to detect the rotational position of the sample cartridge holder 17.
- the spindle 3 is further provided with a positioning disc 15 which is located above the large gear and cooperates with the U-shaped sensor for positioning when the sample cartridge holder 17 is rotated.
- the sample cartridge holder is further provided with a third sensor 4 that detects whether the sample cartridge has been loaded onto the sample cartridge holder to ensure the detection effect.
- the third sensor 4 is, for example, a photoelectric sensor, and the detection is rapid.
- the carousel occult blood detecting analyzer comprises: a bottom plate 20 for supporting each detecting device and component, for example, the sample cartridge rack 17, the driving device, the pressing device and the information collecting device are all disposed on the bottom plate on.
- the bottom plate 20 is conveniently placed on a flat surface such as a table top.
- the carousel occult blood detecting analyzer further comprises: a control device connecting the driving device, the pressing device and the information collecting device, and controlling rotation and information collection of the sample cartridge holder.
- the control The device is a programmable controller or an integrated circuit board. In this way, the structure is simple and easy to carry.
- the sample cartridge holder 17 rotates one turn, and the sensor detects whether the sample cartridge has been loaded onto the sample cartridge holder. Then, the sample cartridge holder 17 rotates the second loop, and the lower plunger presses each sample cartridge one by one, since it is considered After the pressing down, the diluent in the sample box flows out, and the test strip contacts the time to form a reaction, so that there is enough time to complete the reaction, and the detection result is obtained, and then one rotation is performed to complete the scanning and photographing. After the first sample box is pressed down to the first sample box, the information is accurately controlled for 5 minutes. From the first sample box press to the last sample box, the information is collected. The control is 10 minutes, which not only ensures the reaction time, but also guarantees a certain detection speed.
- the main advantages of this analyzer are: 1. The mechanism is simplified to the greatest extent, the analyzer has a simple structure and improved stability. 2. Due to the simplification of the analyzer mechanism, the analyzer is reduced in size and lighter. 3. The analyzer adopts gear transmission, which improves the transmission precision and makes the positioning more accurate. 4. The sample box is housed in the sample box holder, which is convenient for loading and unloading the sample box, facilitating the treatment or recycling of medical waste. At the same time, the sample box holder is also effective in avoiding problems such as dumping and rollover of the sample box.
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Abstract
Description
Claims (10)
- 一种转盘式便隐血检测分析仪,用于检测样本盒,所述样本盒包括透明套筒和置于透明套筒中的采便器和试纸条,其特征在于,所述转盘式便隐血检测分析仪包括:承载多个样本盒的样本盒架,所述样本盒架为圆盘状;驱动装置,驱动所述样本盒架转动;下压装置,将所述样本盒压下;以及信息采集装置,采集所述样本盒中的试纸条上所呈现的色带信息和所述样本盒上的标签信息。
- 如权利要求1所述的转盘式便隐血检测分析仪,其特征在于,所述样本盒架能够做360°回转运动,所述样本盒架底部设有多个夹持或承载样本盒的夹持槽,夹持槽的侧上方为用于对所述样本盒的正面和背面拍照和扫码的开窗。
- 如权利要求1所述的转盘式便隐血检测分析仪,其特征在于,所述驱动装置包括:样本盒架驱动电机、与所述样本盒架驱动电机连接的齿轮组、以及与所述齿轮组连接的主轴,所述样本盒架连接在所述主轴上。
- 如权利要求1所述的转盘式便隐血检测分析仪,其特征在于,所述下压装置包括:支架、设置在所述支架上的下压驱动电机、受所述下压驱动电机驱动的下压杆、以及将所述下压杆铰接在所述支架上的铰轴。
- 如权利要求1所述的转盘式便隐血检测分析仪,其特征在于,所述信息采集装置包括:设置在所述样本盒架内侧的扫码器、以及设置在所述样本盒架外侧的相机,所述扫码器和所述相机的连线与所述样本盒架的径向方向相同。
- 如权利要求4所述的转盘式便隐血检测分析仪,其特征在于,所述下压装置还包括:检测所述下压杆位置的第一传感器。
- 如权利要求3所述的转盘式便隐血检测分析仪,其特征在于,所述驱动装置还包括:检测所述样本盒架位置的第二传感器。
- 如权利要求3所述的转盘式便隐血检测分析仪,其特征在于,所述样本盒架还设有:检测所述样本盒是否已经被载入到所述样本盒架上的第三传感器。
- 如权利要求1所述的转盘式便隐血检测分析仪,其特征在于,所述转盘式便隐血检测分析仪包括:底板,所述样本盒架、驱动装置、下压装置和信息采集装置均设置在所述 底板上。
- 如权利要求1所述的转盘式便隐血检测分析仪,其特征在于,所述转盘式便隐血检测分析仪还包括:控制装置,连接所述驱动装置、所述下压装置和所述信息采集装置。
Priority Applications (4)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
CA3001631A CA3001631A1 (en) | 2015-10-30 | 2016-09-29 | Rotating disc type fecal occult blood detection analyzer |
AU2016347114A AU2016347114A1 (en) | 2015-10-30 | 2016-09-29 | Rotating disc type fecal occult blood detection analyzer |
US15/771,485 US10684300B2 (en) | 2015-10-30 | 2016-09-29 | Rotating disc type fecal occult blood detection analyzer |
EP16858886.1A EP3370067A4 (en) | 2015-10-30 | 2016-09-29 | FECAL BLOOD DETECTION ANALYZER OF ROTARY DISC TYPE |
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
CN201510726035.8A CN106645767B (zh) | 2015-10-30 | 2015-10-30 | 转盘式便隐血检测分析仪 |
CN201510726035.8 | 2015-10-30 |
Publications (1)
Publication Number | Publication Date |
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WO2017071450A1 true WO2017071450A1 (zh) | 2017-05-04 |
Family
ID=58631278
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
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PCT/CN2016/100781 WO2017071450A1 (zh) | 2015-10-30 | 2016-09-29 | 转盘式便隐血检测分析仪 |
Country Status (6)
Country | Link |
---|---|
US (1) | US10684300B2 (zh) |
EP (1) | EP3370067A4 (zh) |
CN (1) | CN106645767B (zh) |
AU (1) | AU2016347114A1 (zh) |
CA (1) | CA3001631A1 (zh) |
WO (1) | WO2017071450A1 (zh) |
Cited By (2)
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CN110208561A (zh) * | 2019-06-13 | 2019-09-06 | 深圳市爱康生物科技有限公司 | 一种全自动血小板抗体检测装置 |
CN110274915A (zh) * | 2019-07-30 | 2019-09-24 | 金陵科技学院 | 一种条形样品盘式视觉检测装置 |
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CN107748250A (zh) * | 2017-11-16 | 2018-03-02 | 北京泰杰伟业科技有限公司 | 一种胶体金免疫分析仪 |
CN110275020A (zh) * | 2019-08-01 | 2019-09-24 | 郑州迈迪迅医疗科技有限公司 | 一种转轮式层析检测装置 |
CN110632334B (zh) * | 2019-10-11 | 2023-04-18 | 万华普曼生物工程有限公司 | 样本自动检测装置 |
CN112014571A (zh) * | 2020-08-20 | 2020-12-01 | 金华科生物技术河北有限公司 | C-反应蛋白胶体金法半定量检测装置 |
CN113804871A (zh) * | 2021-09-17 | 2021-12-17 | 广州蓝勃生物科技有限公司 | 一种生化检测装置 |
CN115105129B (zh) * | 2022-07-05 | 2023-06-02 | 北京积水潭医院 | 一种自动化核酸采样检测试管收集装置 |
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2015
- 2015-10-30 CN CN201510726035.8A patent/CN106645767B/zh active Active
-
2016
- 2016-09-29 US US15/771,485 patent/US10684300B2/en active Active
- 2016-09-29 WO PCT/CN2016/100781 patent/WO2017071450A1/zh active Application Filing
- 2016-09-29 EP EP16858886.1A patent/EP3370067A4/en not_active Withdrawn
- 2016-09-29 CA CA3001631A patent/CA3001631A1/en not_active Abandoned
- 2016-09-29 AU AU2016347114A patent/AU2016347114A1/en not_active Abandoned
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Cited By (3)
Publication number | Priority date | Publication date | Assignee | Title |
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CN110208561A (zh) * | 2019-06-13 | 2019-09-06 | 深圳市爱康生物科技有限公司 | 一种全自动血小板抗体检测装置 |
CN110274915A (zh) * | 2019-07-30 | 2019-09-24 | 金陵科技学院 | 一种条形样品盘式视觉检测装置 |
CN110274915B (zh) * | 2019-07-30 | 2024-01-30 | 金陵科技学院 | 一种条形样品盘式视觉检测装置 |
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US20180340950A1 (en) | 2018-11-29 |
CA3001631A1 (en) | 2017-05-04 |
EP3370067A4 (en) | 2019-07-10 |
CN106645767B (zh) | 2019-10-11 |
CN106645767A (zh) | 2017-05-10 |
AU2016347114A1 (en) | 2018-05-17 |
US10684300B2 (en) | 2020-06-16 |
EP3370067A1 (en) | 2018-09-05 |
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