WO2016195016A8 - 新規なトリグリセリド及びその用途 - Google Patents

新規なトリグリセリド及びその用途 Download PDF

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Publication number
WO2016195016A8
WO2016195016A8 PCT/JP2016/066405 JP2016066405W WO2016195016A8 WO 2016195016 A8 WO2016195016 A8 WO 2016195016A8 JP 2016066405 W JP2016066405 W JP 2016066405W WO 2016195016 A8 WO2016195016 A8 WO 2016195016A8
Authority
WO
WIPO (PCT)
Prior art keywords
triglyceride
hya
optical isomer
present
novel
Prior art date
Application number
PCT/JP2016/066405
Other languages
English (en)
French (fr)
Other versions
WO2016195016A1 (ja
Inventor
靖記 米島
順 小川
重信 岸野
Original Assignee
日東薬品工業株式会社
国立大学法人京都大学
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by 日東薬品工業株式会社, 国立大学法人京都大学 filed Critical 日東薬品工業株式会社
Priority to US15/578,694 priority Critical patent/US10287234B2/en
Priority to CN201680045378.0A priority patent/CN107922308A/zh
Priority to JP2017522247A priority patent/JP6806339B2/ja
Priority to EP16803450.2A priority patent/EP3305756B1/en
Publication of WO2016195016A1 publication Critical patent/WO2016195016A1/ja
Publication of WO2016195016A8 publication Critical patent/WO2016195016A8/ja
Priority to HK18109286.4A priority patent/HK1249897A1/zh
Priority to HK18109285.5A priority patent/HK1249896A1/zh

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00—Cosmetics or similar toiletry preparations
    • A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/33—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing oxygen
    • A61K8/37—Esters of carboxylic acids
    • A61K8/375—Esters of carboxylic acids the alcohol moiety containing more than one hydroxy group
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C69/00—Esters of carboxylic acids; Esters of carbonic or haloformic acids
    • C07C69/66—Esters of carboxylic acids having esterified carboxylic groups bound to acyclic carbon atoms and having any of the groups OH, O—metal, —CHO, keto, ether, acyloxy, groups, groups, or in the acid moiety
    • C07C69/73—Esters of carboxylic acids having esterified carboxylic groups bound to acyclic carbon atoms and having any of the groups OH, O—metal, —CHO, keto, ether, acyloxy, groups, groups, or in the acid moiety of unsaturated acids
    • C07C69/732—Esters of carboxylic acids having esterified carboxylic groups bound to acyclic carbon atoms and having any of the groups OH, O—metal, —CHO, keto, ether, acyloxy, groups, groups, or in the acid moiety of unsaturated acids of unsaturated hydroxy carboxylic acids
    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23D—EDIBLE OILS OR FATS, e.g. MARGARINES, SHORTENINGS, COOKING OILS
    • A23D9/00—Other edible oils or fats, e.g. shortenings, cooking oils
    • A23D9/007—Other edible oils or fats, e.g. shortenings, cooking oils characterised by ingredients other than fatty acid triglycerides
    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23K—FODDER
    • A23K20/00—Accessory food factors for animal feeding-stuffs
    • A23K20/10—Organic substances
    • A23K20/158—Fatty acids; Fats; Products containing oils or fats
    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23L—FOODS, FOODSTUFFS, OR NON-ALCOHOLIC BEVERAGES, NOT COVERED BY SUBCLASSES A21D OR A23B-A23J; THEIR PREPARATION OR TREATMENT, e.g. COOKING, MODIFICATION OF NUTRITIVE QUALITIES, PHYSICAL TREATMENT; PRESERVATION OF FOODS OR FOODSTUFFS, IN GENERAL
    • A23L33/00—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof
    • A23L33/10—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof using additives
    • A23L33/115—Fatty acids or derivatives thereof; Fats or oils
    • A23L33/12—Fatty acids or derivatives thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/21—Esters, e.g. nitroglycerine, selenocyanates
    • A61K31/215—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids
    • A61K31/22—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids of acyclic acids, e.g. pravastatin
    • A61K31/23—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids of acyclic acids, e.g. pravastatin of acids having a carboxyl group bound to a chain of seven or more carbon atoms
    • A61K31/231—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids of acyclic acids, e.g. pravastatin of acids having a carboxyl group bound to a chain of seven or more carbon atoms having one or two double bonds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00—Cosmetics or similar toiletry preparations
    • A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/33—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing oxygen
    • A61K8/37—Esters of carboxylic acids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
    • A61Q1/00—Make-up preparations; Body powders; Preparations for removing make-up
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
    • A61Q19/00—Preparations for care of the skin
    • C—CHEMISTRY; METALLURGY
    • C11—ANIMAL OR VEGETABLE OILS, FATS, FATTY SUBSTANCES OR WAXES; FATTY ACIDS THEREFROM; DETERGENTS; CANDLES
    • C11C—FATTY ACIDS FROM FATS, OILS OR WAXES; CANDLES; FATS, OILS OR FATTY ACIDS BY CHEMICAL MODIFICATION OF FATS, OILS, OR FATTY ACIDS OBTAINED THEREFROM
    • C11C3/00—Fats, oils, or fatty acids by chemical modification of fats, oils, or fatty acids obtained therefrom
    • C—CHEMISTRY; METALLURGY
    • C11—ANIMAL OR VEGETABLE OILS, FATS, FATTY SUBSTANCES OR WAXES; FATTY ACIDS THEREFROM; DETERGENTS; CANDLES
    • C11C—FATTY ACIDS FROM FATS, OILS OR WAXES; CANDLES; FATS, OILS OR FATTY ACIDS BY CHEMICAL MODIFICATION OF FATS, OILS, OR FATTY ACIDS OBTAINED THEREFROM
    • C11C3/00—Fats, oils, or fatty acids by chemical modification of fats, oils, or fatty acids obtained therefrom
    • C11C3/02—Fats, oils, or fatty acids by chemical modification of fats, oils, or fatty acids obtained therefrom by esterification of fatty acids with glycerol
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2800/00—Properties of cosmetic compositions or active ingredients thereof or formulation aids used therein and process related aspects
    • A61K2800/80—Process related aspects concerning the preparation of the cosmetic composition or the storage or application thereof
    • A61K2800/92—Oral administration
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07B—GENERAL METHODS OF ORGANIC CHEMISTRY; APPARATUS THEREFOR
    • C07B53/00—Asymmetric syntheses

Landscapes

  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Polymers & Plastics (AREA)
  • Engineering & Computer Science (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Food Science & Technology (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • Organic Chemistry (AREA)
  • Emergency Medicine (AREA)
  • Epidemiology (AREA)
  • Nutrition Science (AREA)
  • Birds (AREA)
  • Zoology (AREA)
  • Animal Husbandry (AREA)
  • Mycology (AREA)
  • Dermatology (AREA)
  • Wood Science & Technology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Medicinal Chemistry (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Coloring Foods And Improving Nutritive Qualities (AREA)
  • Edible Oils And Fats (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Cosmetics (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Fats And Perfumes (AREA)
  • Fodder In General (AREA)

Abstract

本発明は、ＨＹＡ本来の優れた生理学的機能を有しつつ、摂取及び取扱いが容易な新規ＨＹＡ誘導体、及びその用途を提供する。　本発明は、グリセリンの水酸基とエステル結合を形成する少なくとも一つの脂肪酸が、１０－ヒドロキシ－シス－１２－オクタデセン酸であることを特徴とする、トリグリセリド又はその光学異性体、及びそれを含有する組成物（食用油脂、食品、医薬、化粧料等）に関する。
PCT/JP2016/066405 2015-06-02 2016-06-02 新規なトリグリセリド及びその用途 WO2016195016A1 (ja)

Priority Applications (6)

Application Number Priority Date Filing Date Title
US15/578,694 US10287234B2 (en) 2015-06-02 2016-06-02 Triglyceride and use thereof
CN201680045378.0A CN107922308A (zh) 2015-06-02 2016-06-02 新型甘油三酯及其用途
JP2017522247A JP6806339B2 (ja) 2015-06-02 2016-06-02 新規なトリグリセリド及びその用途
EP16803450.2A EP3305756B1 (en) 2015-06-02 2016-06-02 Novel triglyceride and use thereof
HK18109286.4A HK1249897A1 (zh) 2015-06-02 2018-07-18 新型甘油三酯及其用途
HK18109285.5A HK1249896A1 (zh) 2015-06-02 2018-07-18 新的甘油三酯和其用途

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
JP2015112604 2015-06-02
JP2015-112604 2015-06-02

Publications (2)

Publication Number Publication Date
WO2016195016A1 WO2016195016A1 (ja) 2016-12-08
WO2016195016A8 true WO2016195016A8 (ja) 2017-03-16

Family

ID=57441387

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/JP2016/066405 WO2016195016A1 (ja) 2015-06-02 2016-06-02 新規なトリグリセリド及びその用途

Country Status (6)

Country Link
US (1) US10287234B2 (ja)
EP (1) EP3305756B1 (ja)
JP (1) JP6806339B2 (ja)
CN (1) CN107922308A (ja)
HK (2) HK1249896A1 (ja)
WO (1) WO2016195016A1 (ja)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ES2946922T3 (es) 2017-08-31 2023-07-27 Univ Kyoto Multímeros de ácido graso hidroxilado y método de producción de los mismos
WO2023063175A1 (ja) * 2021-10-13 2023-04-20 株式会社Ｊ－オイルミルズ 水添臭付与剤、その製造方法、食品に水添臭を付与する方法、食品に水添臭を付与するための酸化処理物の使用、及び水添臭付与剤を含む食品
CN114288281A (zh) * 2021-12-07 2022-04-08 上海中医药大学附属岳阳中西医结合医院 三亚油酸甘油酯在制备预防和/或治疗特应性皮炎的药物中的应用

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPH0374315A (ja) * 1989-08-11 1991-03-28 Nisshin Oil Mills Ltd:The エステル化生成物及びこれを含有する化粧料又は外用剤
WO2004085582A2 (en) 2003-03-27 2004-10-07 Suntory Limited Lipid-improving agent and composition containing lipid-improving agent
JP2009051732A (ja) * 2005-12-13 2009-03-12 Meiji Seika Kaisha Ltd Ｐｐａｒリガンド活性を有する組成物
EP2405902B1 (en) * 2009-03-09 2021-07-21 Basf As Compositions comprising a fatty acid oil mixture and a surfactant, and methods and uses thereof
US9719115B2 (en) * 2012-05-10 2017-08-01 Kyoto University Method for producing oxo fatty acid and rare fatty acid
EP2913051B1 (en) 2012-10-29 2018-09-19 Kyoto University Metabolism-improving agent comprising rare fatty acid
JP6241681B2 (ja) 2013-02-21 2017-12-06 国立大学法人京都大学 水酸化脂肪酸を含む腸管保護剤
CA2910680A1 (en) 2013-05-20 2014-11-27 Iowa State University Research Foundation, Inc. Thermoplastic elastomers via reversible addition-fragmentation chain transfer polymerization of triglycerides

Also Published As

Publication number Publication date
US10287234B2 (en) 2019-05-14
JP6806339B2 (ja) 2021-01-06
WO2016195016A1 (ja) 2016-12-08
HK1249896A1 (zh) 2018-11-16
CN107922308A (zh) 2018-04-17
HK1249897A1 (zh) 2018-11-16
EP3305756A4 (en) 2019-02-13
EP3305756B1 (en) 2022-01-05
JPWO2016195016A1 (ja) 2018-04-19
EP3305756A1 (en) 2018-04-11
US20180170854A1 (en) 2018-06-21

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