WO2016195017A8 - １０－ヒドロキシ－シス－１２－オクタデセン酸アルキルエステル及びその用途 - Google Patents

１０－ヒドロキシ－シス－１２－オクタデセン酸アルキルエステル及びその用途 Download PDF

Info

Publication number
WO2016195017A8
WO2016195017A8 PCT/JP2016/066406 JP2016066406W WO2016195017A8 WO 2016195017 A8 WO2016195017 A8 WO 2016195017A8 JP 2016066406 W JP2016066406 W JP 2016066406W WO 2016195017 A8 WO2016195017 A8 WO 2016195017A8
Authority
WO
WIPO (PCT)
Prior art keywords
cis
hydroxy
octadecenoic acid
acid alkyl
alkyl ester
Prior art date
Application number
PCT/JP2016/066406
Other languages
English (en)
French (fr)
Other versions
WO2016195017A1 (ja
Inventor
靖記 米島
順 小川
重信 岸野
Original Assignee
日東薬品工業株式会社
国立大学法人京都大学
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by 日東薬品工業株式会社, 国立大学法人京都大学 filed Critical 日東薬品工業株式会社
Priority to JP2017522248A priority Critical patent/JP6806340B2/ja
Priority to US15/578,704 priority patent/US10285966B2/en
Priority to ES16803451T priority patent/ES2964978T3/es
Priority to EP16803451.0A priority patent/EP3305757B1/en
Priority to CN201680045377.6A priority patent/CN107848948A/zh
Publication of WO2016195017A1 publication Critical patent/WO2016195017A1/ja
Publication of WO2016195017A8 publication Critical patent/WO2016195017A8/ja
Priority to HK18109283.7A priority patent/HK1249894A1/zh
Priority to HK18109284.6A priority patent/HK1249895A1/zh

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/21—Esters, e.g. nitroglycerine, selenocyanates
    • A61K31/215—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids
    • A61K31/22—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids of acyclic acids, e.g. pravastatin
    • A61K31/23—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids of acyclic acids, e.g. pravastatin of acids having a carboxyl group bound to a chain of seven or more carbon atoms
    • A61K31/231—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids of acyclic acids, e.g. pravastatin of acids having a carboxyl group bound to a chain of seven or more carbon atoms having one or two double bonds
    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23D—EDIBLE OILS OR FATS, e.g. MARGARINES, SHORTENINGS, COOKING OILS
    • A23D9/00—Other edible oils or fats, e.g. shortenings, cooking oils
    • A23D9/007—Other edible oils or fats, e.g. shortenings, cooking oils characterised by ingredients other than fatty acid triglycerides
    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23K—FODDER
    • A23K20/00—Accessory food factors for animal feeding-stuffs
    • A23K20/10—Organic substances
    • A23K20/158—Fatty acids; Fats; Products containing oils or fats
    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23L—FOODS, FOODSTUFFS, OR NON-ALCOHOLIC BEVERAGES, NOT COVERED BY SUBCLASSES A21D OR A23B-A23J; THEIR PREPARATION OR TREATMENT, e.g. COOKING, MODIFICATION OF NUTRITIVE QUALITIES, PHYSICAL TREATMENT; PRESERVATION OF FOODS OR FOODSTUFFS, IN GENERAL
    • A23L33/00—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof
    • A23L33/10—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof using additives
    • A23L33/115—Fatty acids or derivatives thereof; Fats or oils
    • A23L33/12—Fatty acids or derivatives thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00—Cosmetics or similar toiletry preparations
    • A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/33—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing oxygen
    • A61K8/36—Carboxylic acids; Salts or anhydrides thereof
    • A61K8/361—Carboxylic acids having more than seven carbon atoms in an unbroken chain; Salts or anhydrides thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00—Cosmetics or similar toiletry preparations
    • A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/33—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing oxygen
    • A61K8/37—Esters of carboxylic acids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/16—Drugs for disorders of the alimentary tract or the digestive system for liver or gallbladder disorders, e.g. hepatoprotective agents, cholagogues, litholytics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/04—Anorexiants; Antiobesity agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/06—Antihyperlipidemics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
    • A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
    • A61Q1/00—Make-up preparations; Body powders; Preparations for removing make-up
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
    • A61Q19/00—Preparations for care of the skin
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C69/00—Esters of carboxylic acids; Esters of carbonic or haloformic acids
    • C07C69/66—Esters of carboxylic acids having esterified carboxylic groups bound to acyclic carbon atoms and having any of the groups OH, O—metal, —CHO, keto, ether, acyloxy, groups, groups, or in the acid moiety
    • C07C69/73—Esters of carboxylic acids having esterified carboxylic groups bound to acyclic carbon atoms and having any of the groups OH, O—metal, —CHO, keto, ether, acyloxy, groups, groups, or in the acid moiety of unsaturated acids
    • C07C69/732—Esters of carboxylic acids having esterified carboxylic groups bound to acyclic carbon atoms and having any of the groups OH, O—metal, —CHO, keto, ether, acyloxy, groups, groups, or in the acid moiety of unsaturated acids of unsaturated hydroxy carboxylic acids

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Polymers & Plastics (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Emergency Medicine (AREA)
  • Food Science & Technology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Epidemiology (AREA)
  • Diabetes (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • Birds (AREA)
  • Hematology (AREA)
  • Obesity (AREA)
  • Nutrition Science (AREA)
  • Mycology (AREA)
  • Dermatology (AREA)
  • Animal Husbandry (AREA)
  • Zoology (AREA)
  • Endocrinology (AREA)
  • Child & Adolescent Psychology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Pain & Pain Management (AREA)
  • Rheumatology (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Fodder In General (AREA)
  • Coloring Foods And Improving Nutritive Qualities (AREA)
  • Cosmetics (AREA)

Abstract

ＨＹＡ本来の優れた生理学的機能を有しつつ、摂取及び取扱いが容易な新規ＨＹＡ誘導体、及びその用途を提供する。　本発明は、１０－ヒドロキシ－シス－１２－オクタデセン酸アルキルエステル若しくはその光学異性体、又は、１０－ヒドロキシ－シス－１２－オクタデセン酸と二価アルカノールとのエステル若しくはその光学異性体、及びそれらを含有する組成物（食用油脂、食品、医薬、化粧料等）に関する。
PCT/JP2016/066406 2015-06-02 2016-06-02 １０－ヒドロキシ－シス－１２－オクタデセン酸アルキルエステル及びその用途 WO2016195017A1 (ja)

Priority Applications (7)

Application Number Priority Date Filing Date Title
JP2017522248A JP6806340B2 (ja) 2015-06-02 2016-06-02 １０−ヒドロキシ−シス−１２−オクタデセン酸アルキルエステル及びその用途
US15/578,704 US10285966B2 (en) 2015-06-02 2016-06-02 10-hydroxy-cis-12-octadecenoic acid alkyl ester and use thereof
ES16803451T ES2964978T3 (es) 2015-06-02 2016-06-02 Ester alquílico del ácido 10-hidroxi-cis-12-octadecenoico y su uso
EP16803451.0A EP3305757B1 (en) 2015-06-02 2016-06-02 10-hydroxy-cis-12-octadecenoic acid alkyl ester and use thereof
CN201680045377.6A CN107848948A (zh) 2015-06-02 2016-06-02 10‑羟基‑顺‑12‑十八碳烯酸烷基酯及其用途
HK18109283.7A HK1249894A1 (zh) 2015-06-02 2018-07-18 10-羥基-順-12-十八碳烯酸烷基酯及其用途
HK18109284.6A HK1249895A1 (zh) 2015-06-02 2018-07-18 10-羥基-順-12-十八碳烯酸烷基酯及其用途

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
JP2015112606 2015-06-02
JP2015-112606 2015-06-02

Publications (2)

Publication Number Publication Date
WO2016195017A1 WO2016195017A1 (ja) 2016-12-08
WO2016195017A8 true WO2016195017A8 (ja) 2017-03-16

Family

ID=57441523

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/JP2016/066406 WO2016195017A1 (ja) 2015-06-02 2016-06-02 １０－ヒドロキシ－シス－１２－オクタデセン酸アルキルエステル及びその用途

Country Status (7)

Country Link
US (1) US10285966B2 (ja)
EP (1) EP3305757B1 (ja)
JP (1) JP6806340B2 (ja)
CN (1) CN107848948A (ja)
ES (1) ES2964978T3 (ja)
HK (2) HK1249895A1 (ja)
WO (1) WO2016195017A1 (ja)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US11130974B2 (en) 2017-08-31 2021-09-28 Kyoto University Hydroxylated fatty acid homopolymer and production method thereof
TW202320647A (zh) * 2021-10-13 2023-06-01 日商Ｊ 制油股份有限公司 氫化味賦予劑、其製造方法、對食品賦予氫化味之方法、用以對食品賦予氫化味之氧化處理物之用途、及包含氫化味賦予劑之食品
CN115399462A (zh) * 2022-09-19 2022-11-29 四川新雅轩食品有限公司 一种食用菌汤及其制备方法

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
MY144341A (en) 2003-03-27 2011-08-29 Suntory Holdings Ltd Lipid-improving agent and composition containing lipid-improving agent
JP2009051732A (ja) * 2005-12-13 2009-03-12 Meiji Seika Kaisha Ltd Ｐｐａｒリガンド活性を有する組成物
WO2013168310A1 (ja) * 2012-05-10 2013-11-14 国立大学法人京都大学 オキソ脂肪酸及び希少脂肪酸の製造法
EP2706117A1 (en) 2012-09-07 2014-03-12 Basf Se Process for preparing sebacic acid
EP2913051B1 (en) * 2012-10-29 2018-09-19 Kyoto University Metabolism-improving agent comprising rare fatty acid
WO2014129384A1 (ja) 2013-02-21 2014-08-28 国立大学法人京都大学 水酸化脂肪酸を含む腸管保護剤

Also Published As

Publication number Publication date
EP3305757A1 (en) 2018-04-11
EP3305757C0 (en) 2023-09-20
JPWO2016195017A1 (ja) 2018-03-29
EP3305757B1 (en) 2023-09-20
CN107848948A (zh) 2018-03-27
HK1249894A1 (zh) 2018-11-16
US10285966B2 (en) 2019-05-14
ES2964978T3 (es) 2024-04-10
WO2016195017A1 (ja) 2016-12-08
US20180318248A1 (en) 2018-11-08
JP6806340B2 (ja) 2021-01-06
EP3305757A4 (en) 2019-02-27
HK1249895A1 (zh) 2018-11-16

Similar Documents

Publication Publication Date Title
WO2017095944A8 (en) Methods and compositions relating to chondrisomes from blood products
EP3661600A4 (en) FATTY ACID ANALOGS AND ITS USE IN THE TREATMENT OF DISEASES RELATED TO METABOLISM SYNDROME
WO2016030644A3 (fr) Procédé d'induction de la synthèse des phycobiliproteines
WO2016195017A8 (ja) １０－ヒドロキシ－シス－１２－オクタデセン酸アルキルエステル及びその用途
WO2016195016A8 (ja) 新規なトリグリセリド及びその用途
EP3677121A4 (en) COMPOSITION OF FAT OR OIL CONTAINING AN UNSATURATED FATTY ACID
EP3264908A4 (en) Addition of edible fat (lipids) to hay for enhancing the nutritional value and digestibility and reducing the toxicity risk
ZA202103212B (en) Composition comprising a choline salt of a fatty acid and its use as a fungicide
WO2016118882A8 (en) Fragrance and flavor compositions comprising neopentyl glycol diacetate
EP3466267A4 (en) CHOCOLATE-LIKE FOOD CONTAINING HIGHLY UNSATURATED FATTY ACID
EP3692798A4 (en) WHITE CHOCOLATE-TYPE FOOD CONTAINING HIGHLY UNSATURATED FATTY ACID
BR112017012524A2 (pt) composição contendo éster parcial de carboidrato
EP3902535A4 (en) CANNABIDIOL ACID ESTERS FOR COSMETIC OR EDIBLE COMPOSITIONS
WO2016032127A3 (ko) Tlr4에 lps와의 경쟁적 결합을 통한 항산화 및 항염증 활성을 갖는 신규 화합물 및 이의 의학적 용도
AU2018904835A0 (en) Fatty acid compositions and the use thereof
TH159673B (th) ถาดใส่อาหาร
TH184402B (th) ชั้นวางของ
TH70718S1 (th) ชั้นวางกระถางต้นไม้
TH184298S (th) ชั้นวางกระถางต้นไม้
UA35837S (uk) Підставка «ледовар» для продажу цукерок
PL402617A1 (pl) Wyrób alkoholowy
TH162909B (th) ตู้แช่เย็น
TH54054S1 (th) อุปกรณ์เก็บเกี่ยวผลผลิตทางการเกษตร
TH155746S (th) อุปกรณ์เก็บเกี่ยวผลผลิตทางการเกษตร
TH171055B (th) ชิ้นส่วนถาดใส่ของสำหรับตู้เย็น

Legal Events

Date Code Title Description
121 Ep: the epo has been informed by wipo that ep was designated in this application

Ref document number: 16803451

Country of ref document: EP

Kind code of ref document: A1

ENP Entry into the national phase

Ref document number: 2017522248

Country of ref document: JP

Kind code of ref document: A

WWE Wipo information: entry into national phase

Ref document number: 15578704

Country of ref document: US

NENP Non-entry into the national phase

Ref country code: DE

WWE Wipo information: entry into national phase

Ref document number: 2016803451

Country of ref document: EP