WO2016165206A1 - 用于o2o线下调理的祛痘中药组合物及其制备方法 - Google Patents

用于o2o线下调理的祛痘中药组合物及其制备方法 Download PDF

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Publication number
WO2016165206A1
WO2016165206A1 PCT/CN2015/081325 CN2015081325W WO2016165206A1 WO 2016165206 A1 WO2016165206 A1 WO 2016165206A1 CN 2015081325 W CN2015081325 W CN 2015081325W WO 2016165206 A1 WO2016165206 A1 WO 2016165206A1
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parts
mulberry
medicinal composition
rhubarb
cassia
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PCT/CN2015/081325
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English (en)
French (fr)
Inventor
张贯京
陈兴明
葛新科
张少鹏
方静芳
普拉纽克克里斯基捏
古列莎艾琳娜
波达别特伊万
高伟明
梁昊原
梁艳妮
周荣
李慧玲
邢立立
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Shenzhen Qianhai AnyCheck Information Technology Co Ltd
E Techno Information Technologies Co Ltd
Bio Tech Academy China Co Ltd
Shenzhen Gongchuang Science and Technology Development Co Ltd
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Shenzhen Qianhai AnyCheck Information Technology Co Ltd
E Techno Information Technologies Co Ltd
Bio Tech Academy China Co Ltd
Shenzhen Gongchuang Science and Technology Development Co Ltd
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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/74—Rubiaceae (Madder family)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/48—Fabaceae or Leguminosae (Pea or Legume family); Caesalpiniaceae; Mimosaceae; Papilionaceae
    • A61K36/483—Gleditsia (locust)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/48—Fabaceae or Leguminosae (Pea or Legume family); Caesalpiniaceae; Mimosaceae; Papilionaceae
    • A61K36/489—Sophora, e.g. necklacepod or mamani
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/53—Lamiaceae or Labiatae (Mint family), e.g. thyme, rosemary or lavender
    • A61K36/539—Scutellaria (skullcap)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/60—Moraceae (Mulberry family), e.g. breadfruit or fig
    • A61K36/605—Morus (mulberry)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/70—Polygonaceae (Buckwheat family), e.g. spineflower or dock
    • A61K36/704—Polygonum, e.g. knotweed
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/70—Polygonaceae (Buckwheat family), e.g. spineflower or dock
    • A61K36/708—Rheum (rhubarb)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/75—Rutaceae (Rue family)
    • A61K36/756—Phellodendron, e.g. corktree
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/80—Scrophulariaceae (Figwort family)
    • A61K36/804—Rehmannia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/88—Liliopsida (monocotyledons)
    • A61K36/899—Poaceae or Gramineae (Grass family), e.g. bamboo, corn or sugar cane
    • A61K36/8994—Coix (Job's tears)

Definitions

  • the invention relates to the technical field of medicine, in particular to a acne Chinese medicine composition for O2O line conditioning and a preparation method thereof.
  • Acne also known as acne, is a chronic inflammatory lesion of the follicular sebaceous gland unit.
  • the main features of acne are acne, pustules, cysts and scars. Its induction is associated with a variety of factors such as increased androgen secretion, increased sebaceous gland secretion, hyperkeratosis of hair follicle glands, and inflammation.
  • acne drugs on the market, but in general, the price of western medicine is expensive, and the side effects are very large.
  • the efficacy of common Chinese medicine is very slow, sometimes the treatment is not complete, leaving scars and giving patients There are many troubles that affect the physical and mental health of the patient.
  • the object of the present invention is to provide a acne Chinese medicine composition for O2O line conditioning and a preparation method thereof, which can achieve the effects of clearing away heat and detoxifying, rubbing oil, reducing inflammation and removing acne.
  • the present invention provides a acne Chinese medicine composition for O2O line conditioning, which comprises the following parts by weight:
  • Rhubarb 2 ⁇ 8 parts, Astragalus: 2 ⁇ 8 parts, Cork: 9 ⁇ 17 parts, Wild chrysanthemum: 7 ⁇ 12 parts, Hedyotis: 9 ⁇ 17 parts, Raw glutinous rice: 2 ⁇ 8 parts, Mulberry skin : 7 ⁇ 12 servings, Cassia: 9 ⁇ 17 servings, Shouwu: 9 ⁇ 17 servings, Coix seed: 7 ⁇ 12 servings, Mulberry leaves: 2 ⁇ 8 servings, Saponin thorns: 2 ⁇ 8 servings, Honeysuckle: 5 ⁇ 11 Share, habitat: 7 to 12 servings.
  • the traditional Chinese medicine composition consists of the following parts by weight:
  • Rhubarb 3 ⁇ 5 parts, Astragalus: 4 ⁇ 5 parts, Cork: 15 ⁇ 17 parts, Wild chrysanthemum: 7 ⁇ 10 parts, Hedyotis: 15 ⁇ 17 parts, Raw glutinous rice: 5 ⁇ 8 parts, Mulberry skin : 10 ⁇ 12 servings, Cassia: 15 ⁇ 17 servings, Shouwu: 14 ⁇ 16 servings, Coix seed: 9 ⁇ 10 servings, Mulberry leaves: 4 ⁇ 6 servings, Saponin thorns: 4 ⁇ 5 servings, Honeysuckle: 5 ⁇ 8 Share, habitat: 9 to 10 servings.
  • the traditional Chinese medicine composition consists of the following parts by weight:
  • Rhubarb 4 parts, Astragalus: 4 parts, Cork: 15 parts, Wild chrysanthemum: 7 parts, Hedyotis: 15 parts, Raw glutinous rice: 5 parts, Mulberry white: 10 parts, Cassia: 15 parts, Shouwu: 14 parts, Coix seed: 10 parts, Mulberry leaves: 4 parts, saponin: 5 parts, honeysuckle: 5 parts, habitat: 10 parts.
  • the traditional Chinese medicine composition consists of the following parts by weight:
  • Rhubarb 5 parts, Astragalus: 4 parts, Cork: 15 parts, Wild chrysanthemum: 7 parts, Hedyotis: 15 parts, Raw glutinous rice: 5 parts, Mulberry white: 10 parts, Cassia: 15 parts, Shouwu: 14 parts, Coix seed: 10 parts, Mulberry leaves: 4 parts, saponin: 5 parts, honeysuckle: 5 parts, habitat: 10 parts.
  • the traditional Chinese medicine composition consists of the following parts by weight:
  • Rhubarb 5 parts, Astragalus: 5 parts, Cork: 16 parts, Wild chrysanthemum: 7 parts, Hedyotis: 15 parts, Raw glutinous rice: 5 parts, Mulberry white: 10 parts, Cassia: 15 parts, Shouwu: 14 parts, Coix seed: 10 parts, Mulberry leaves: 4 parts, saponin: 5 parts, honeysuckle: 5 parts, habitat: 10 parts.
  • the traditional Chinese medicine composition consists of the following parts by weight:
  • Rhubarb 5 parts, Astragalus: 5 parts, Cork: 16 parts, Wild chrysanthemum: 8 parts, Hedyotis: 16 parts, Raw glutinous rice: 5 parts, Mulberry white: 10 parts, Cassia: 15 parts, Shouwu: 14 parts, Coix seed: 10 parts, Mulberry leaves: 4 parts, saponin: 5 parts, honeysuckle: 5 parts, habitat: 10 parts.
  • the traditional Chinese medicine composition consists of the following parts by weight:
  • Rhubarb 5 parts, Astragalus: 4 parts, Cork: 16 parts, Wild chrysanthemum: 8 parts, Hedyotis: 16 parts, Raw glutinous rice: 6 parts, Mulberry white: 11 parts, Cassia: 15 parts, Shouwu: 14 parts, Coix seed: 9 parts, Mulberry leaves: 5 parts, saponin: 5 parts, honeysuckle: 5 parts, habitat: 10 parts.
  • the traditional Chinese medicine composition consists of the following parts by weight:
  • Rhubarb 4 parts, Astragalus: 5 parts, Cork: 16 parts, Wild chrysanthemum: 8 parts, Hedyotis: 16 parts, Raw glutinous rice: 6 parts, Mulberry white: 11 parts, Cassia: 15 parts, Shouwu: 14 parts, Coix seed: 10 parts, Mulberry leaves: 4 parts, saponin: 5 parts, honeysuckle: 7.5 parts, habitat: 9 parts.
  • the traditional Chinese medicine composition consists of the following parts by weight:
  • Rhubarb 4 parts, Astragalus: 5 parts, Cork: 17 parts, Wild chrysanthemum: 9 parts, Hedyotis: 16 parts, Raw glutinous rice: 6 parts, Mulberry white: 11 parts, Cassia: 15 parts, Shouwu: 14 parts, Coix seed: 10 parts, Mulberry leaves: 4 parts, saponin: 5 parts, honeysuckle: 7.5 parts, habitat: 9 parts.
  • the traditional Chinese medicine composition consists of the following parts by weight:
  • Rhubarb 4 parts, Astragalus: 5 parts, Cork: 16 parts, Wild chrysanthemum: 10 parts, Hedyotis: 15 parts, Raw glutinous rice: 6 parts, Mulberry white: 11 parts, Cassia: 15 parts, Shouwu: 14 parts, Coix seed: 10 parts, Mulberry leaves: 4 parts, saponin: 5 parts, honeysuckle: 7.5 parts, habitat: 9 parts.
  • the traditional Chinese medicine composition consists of the following parts by weight:
  • Rhubarb 4 parts, Astragalus: 5 parts, Cork: 15 parts, Wild chrysanthemum: 10 parts, Hedyotis: 15 parts, Raw glutinous rice: 5 parts, Mulberry white: 11 parts, Cassia: 15 parts, Shouwu: 14 parts, Coix seed: 10 parts, Mulberry leaves: 4 parts, saponin: 5 parts, honeysuckle: 7.5 parts, habitat: 9 parts.
  • the traditional Chinese medicine composition consists of the following parts by weight:
  • Rhubarb 4 parts, Astragalus: 5 parts, Cork: 16 parts, Wild chrysanthemum: 8 parts, Hedyotis: 16 parts, Raw glutinous rice: 5 parts, Mulberry white: 10 parts, Cassia: 15 parts, Shouwu: 14 parts, Coix seed: 10 parts, Mulberry leaves: 4 parts, saponin: 5 parts, honeysuckle: 7.5 parts, habitat: 9 parts.
  • the traditional Chinese medicine composition consists of the following parts by weight:
  • Rhubarb 4 parts, Astragalus: 5 parts, Cork: 16 parts, Wild chrysanthemum: 8 parts, Hedyotis: 16 parts, Raw glutinous rice: 6 parts, Mulberry white: 10 parts, Cassia: 13 parts, Shouwu: 14 parts, Coix seed: 10 parts, Mulberry leaves: 4 parts, saponin: 5 parts, honeysuckle: 7.5 parts, habitat: 9 parts.
  • the traditional Chinese medicine composition consists of the following parts by weight:
  • Rhubarb 5 parts, Astragalus: 5 parts, Cork: 16 parts, Wild chrysanthemum: 8 parts, Hedyotis: 16 parts, Raw glutinous rice: 6 parts, Mulberry white: 11 parts, Cassia: 16 parts, Shouwu: 15 parts, Coix seed: 10 parts, Mulberry leaves: 4 parts, saponin: 5 parts, honeysuckle: 7.5 parts, habitat: 9 parts.
  • the present invention also provides a preparation method of a acne Chinese medicine composition for O2O line conditioning, the preparation method comprising the following steps:
  • the invention adopts rhubarb, scutellaria, cork, wild chrysanthemum, Hedyotis, raw glutinous rice, mulberry white, cassia seed, Shouwu, coix seed, mulberry leaf, saponin, honeysuckle, and raw land as components in the medicine, through them Synergistic action plays a role in clearing away heat and detoxifying, rubbing oil, reducing inflammation, removing acne, and has a good therapeutic effect on acne, making the skin delicate, white and lustrous, and improving the skin health of the user.
  • the invention provides a acne Chinese medicine composition for O2O offline conditioning, the Chinese medicine composition consisting of the following parts by weight:
  • Rhubarb 2 ⁇ 8 parts, Astragalus: 2 ⁇ 8 parts, Cork: 9 ⁇ 17 parts, Wild chrysanthemum: 7 ⁇ 12 parts, Hedyotis: 9 ⁇ 17 parts, Raw glutinous rice: 2 ⁇ 8 parts, Mulberry skin : 7 ⁇ 12 servings, Cassia: 9 ⁇ 17 servings, Shouwu: 9 ⁇ 17 servings, Coix seed: 7 ⁇ 12 servings, Mulberry leaves: 2 ⁇ 8 servings, Saponin thorns: 2 ⁇ 8 servings, Honeysuckle: 5 ⁇ 11 Share, habitat: 7 to 12 servings.
  • rhubarb has the effect of attacking stagnation, clearing dampness heat, purging fire and cooling blood and detoxification; it is used for real heat constipation, stagnation of abdominal pain, diarrhea, and dampness and jaundice.
  • Astragalus It has the effects of clearing away heat and dampness, cooling blood and detoxifying; it is used for carbuncles and hemorrhoids, warm fever, dampness and jaundice, and red eye syndrome.
  • Cork It has the effects of clearing heat, purging fire, dampness and detoxification; it is used for sore swollen poison, damp heat, diarrhea, and eczema itching.
  • Wild chrysanthemum bitter, spicy, flat; return to the lungs, liver; with heat and detoxification, Shufeng Pinggan; used for the treatment of hemorrhoids, phlegm, dermatitis, erysipelas, eczema.
  • Hedyotis It has the effects of clearing away heat and detoxifying, relieving pain and dispersing and diuretic dehumidification; it is used for sore throat, intestinal cramps and poisonous snake bites. Hedyotis can also be used for wet and hot swollen, hot shower, jaundice and other symptoms.
  • Raw glutinous rice slightly cold, bitter taste; with cooling blood to stop bleeding, clearing liver and purging fire effect; for liver heat red, headache and dizziness.
  • Mulberry white skin It has the effect of diminishing water and swelling, relieving lung and relieving asthma; it is used for facial edema and dysuria.
  • Cassia is the seed of Cassia, which has the effect of clearing the liver and improving eyesight and laxative.
  • Cassia has many uses in life, especially for eye swelling and soreness. It treats red eyes and sore eyes and sore eyes. Easy to cry. This is mainly caused by the liver fire is too strong, Cassia can clear the liver and gallbladder smoldering, often used with gentian, Astragalus, Prunella. It can also be used for hypertensive patients with symptoms such as liver yang disturbance and dizziness.
  • Cassia can make the liver fire that is deposited in the body drop, make the body yin and yang, can smooth the stool and solve the problem of dry stool.
  • Shouwu It has the functions of nourishing liver and kidney, benefiting essence blood, black hair and strong bones and muscles; it is used for spleen deficiency, dizziness, smear, early white, and sore feet. It also promotes hematopoietic function and enhances immune function. Lowering blood fat and anti-atherosclerosis, delaying aging, modern investigation of Shouwu contains vitamin E, preventing wrinkles regeneration. In addition, Shouwu has the function of regulating endocrine and laxative.
  • Coix seed sweet, light, slightly cold, spleen, stomach, lung; with spleen and water, dampness and phlegm, clearing heat and pus, clearing damp heat; can be used to treat edema, diarrhea, tendons , flexion and extension, and athlete's foot embolism.
  • Mulberry leaves It has the effects of evacuating wind and heat, clearing the lungs and moistening dryness, clearing the liver and improving eyesight; it is used for wind-heat cold, lung heat dry cough, dizziness headache, and red eyes.
  • mulberry leaves also have the effect of removing heat, which can eliminate eye fatigue, swelling, clearing blood, nourishing the skin, anti-aging, and freckle, and treat dysentery, edema, and liver.
  • Recent research results have confirmed that mulberry leaf and mulberry bark extract can effectively reduce melanin production, inhibit mildew, and naturally whiten by inhibiting the activity of tyrosinase.
  • Saponin thorn Xin, warm, non-toxic; with swelling and drainage, disinfection and pus, search for wind, insecticidal effect; for swelling and drainage, hurricane insecticide. It is used for the initial onset of acne, pus, and symptoms such as skin and leprosy.
  • Honeysuckle Sexual cold, with the effect of clearing away heat and detoxifying, evacuating wind and heat; used for clearing away heat and detoxifying, thinning throat, eliminating heat and removing trouble. It can treat sores, swollen poison, heat syndrome, diarrhea, flu, acute and chronic tonsillitis, periodontitis and other diseases. In addition to medicinal use, the role of honeysuckle is more magical in its beauty, weight loss and health care. Honeysuckle has the function of removing toxic substances from the body, lowering fat and losing weight, and exerting great protection and repair on the body.
  • rhubarb can effectively improve constipation, dampness and jaundice, help to clear away damp heat, purging fire, cool blood, phlegm and detoxification; jaundice helps to clear away heat, dampness, cool blood, detoxification, and can effectively improve Swollen hemorrhoids, warm disease embolism; Phellodendron helps to clear away heat, purging fire, dampness, detoxification, can effectively improve sore swollen poison, damp heat diarrhea, eczema itching embolism; wild chrysanthemum helps clearing heat and detoxification Fengping liver can effectively improve hemorrhoids, phlegm, dermatitis, erysipelas and eczema; Hedyotis helps to clear away heat and detoxification, relieve pain and disperse, diuretic and dehumidification, and can effectively improve sore, swollen, intestinal cramps and lungs , snake bites embolism; raw glutinous rice helps to cool the blood to
  • the functions of clearing away heat and detoxifying, rubbing fat, reducing inflammation and removing acne have a good therapeutic effect on acne, make the skin delicate and white, lustrous and improve the health of the user.
  • the components of the acne Chinese medicine composition for O2O line conditioning are as follows:
  • Rhubarb 3 ⁇ 5 parts, Astragalus: 4 ⁇ 5 parts, Cork: 15 ⁇ 17 parts, Wild chrysanthemum: 7 ⁇ 10 parts, Hedyotis: 15 ⁇ 17 parts, Raw glutinous rice: 5 ⁇ 8 parts, Mulberry skin : 10 ⁇ 12 servings, Cassia: 15 ⁇ 17 servings, Shouwu: 14 ⁇ 16 servings, Coix seed: 9 ⁇ 10 servings, Mulberry leaves: 4 ⁇ 6 servings, Saponin thorns: 4 ⁇ 5 servings, Honeysuckle: 5 ⁇ 8 Share, habitat: 9 to 10 servings.
  • the components of the acne Chinese medicine composition for O2O line conditioning are as follows:
  • Rhubarb 4 parts, Astragalus: 4 parts, Cork: 15 parts, Wild chrysanthemum: 7 parts, Hedyotis: 15 parts, Raw glutinous rice: 5 parts, Mulberry white: 10 parts, Cassia: 15 parts, Shouwu: 14 parts, Coix seed: 10 parts, Mulberry leaves: 4 parts, saponin: 5 parts, honeysuckle: 5 parts, habitat: 10 parts.
  • the components of the acne Chinese medicine composition for O2O line conditioning are as follows:
  • Rhubarb 5 parts, Astragalus: 4 parts, Cork: 15 parts, Wild chrysanthemum: 7 parts, Hedyotis: 15 parts, Raw glutinous rice: 5 parts, Mulberry white: 10 parts, Cassia: 15 parts, Shouwu: 14 parts, Coix seed: 10 parts, Mulberry leaves: 4 parts, saponin: 5 parts, honeysuckle: 5 parts, habitat: 10 parts.
  • the components of the acne Chinese medicine composition for O2O line conditioning are as follows:
  • Rhubarb 5 parts, Astragalus: 5 parts, Cork: 16 parts, Wild chrysanthemum: 7 parts, Hedyotis: 15 parts, Raw glutinous rice: 5 parts, Mulberry white: 10 parts, Cassia: 15 parts, Shouwu: 14 parts, Coix seed: 10 parts, Mulberry leaves: 4 parts, saponin: 5 parts, honeysuckle: 5 parts, habitat: 10 parts.
  • the components of the acne Chinese medicine composition for O2O line conditioning are as follows:
  • Rhubarb 5 parts, Astragalus: 5 parts, Cork: 16 parts, Wild chrysanthemum: 8 parts, Hedyotis: 16 parts, Raw glutinous rice: 5 parts, Mulberry white: 10 parts, Cassia: 15 parts, Shouwu: 14 parts, Coix seed: 10 parts, Mulberry leaves: 4 parts, saponin: 5 parts, honeysuckle: 5 parts, habitat: 10 parts.
  • the components of the acne Chinese medicine composition for O2O line conditioning are as follows:
  • Rhubarb 5 parts, Astragalus: 4 parts, Cork: 16 parts, Wild chrysanthemum: 8 parts, Hedyotis: 16 parts, Raw glutinous rice: 6 parts, Mulberry white: 11 parts, Cassia: 15 parts, Shouwu: 14 parts, Coix seed: 9 parts, Mulberry leaves: 5 parts, saponin: 5 parts, honeysuckle: 5 parts, habitat: 10 parts.
  • the components of the acne Chinese medicine composition for O2O line conditioning are as follows:
  • Rhubarb 4 parts, Astragalus: 5 parts, Cork: 16 parts, Wild chrysanthemum: 8 parts, Hedyotis: 16 parts, Raw glutinous rice: 6 parts, Mulberry white: 11 parts, Cassia: 15 parts, Shouwu: 14 parts, Coix seed: 10 parts, Mulberry leaves: 4 parts, saponin: 5 parts, honeysuckle: 7.5 parts, habitat: 9 parts.
  • the components of the acne Chinese medicine composition for O2O line conditioning are as follows:
  • Rhubarb 4 parts, Astragalus: 5 parts, Cork: 17 parts, Wild chrysanthemum: 9 parts, Hedyotis: 16 parts, Raw glutinous rice: 6 parts, Mulberry white: 11 parts, Cassia: 15 parts, Shouwu: 14 parts, Coix seed: 10 parts, Mulberry leaves: 4 parts, saponin: 5 parts, honeysuckle: 7.5 parts, habitat: 9 parts.
  • the components of the acne Chinese medicine composition for O2O line conditioning are as follows:
  • Rhubarb 4 parts, Astragalus: 5 parts, Cork: 16 parts, Wild chrysanthemum: 10 parts, Hedyotis: 15 parts, Raw glutinous rice: 6 parts, Mulberry white: 11 parts, Cassia: 15 parts, Shouwu: 14 parts, Coix seed: 10 parts, Mulberry leaves: 4 parts, saponin: 5 parts, honeysuckle: 7.5 parts, habitat: 9 parts.
  • the components of the acne Chinese medicine composition for O2O line conditioning are as follows:
  • Rhubarb 4 parts, Astragalus: 5 parts, Cork: 15 parts, Wild chrysanthemum: 10 parts, Hedyotis: 15 parts, Raw glutinous rice: 5 parts, Mulberry white: 11 parts, Cassia: 15 parts, Shouwu: 14 parts, Coix seed: 10 parts, Mulberry leaves: 4 parts, saponin: 5 parts, honeysuckle: 7.5 parts, habitat: 9 parts.
  • the components of the acne Chinese medicine composition for O2O line conditioning are as follows:
  • Rhubarb 4 parts, Astragalus: 5 parts, Cork: 16 parts, Wild chrysanthemum: 8 parts, Hedyotis: 16 parts, Raw glutinous rice: 5 parts, Mulberry white: 10 parts, Cassia: 15 parts, Shouwu: 14 parts, Coix seed: 10 parts, Mulberry leaves: 4 parts, saponin: 5 parts, honeysuckle: 7.5 parts, habitat: 9 parts.
  • the components of the acne Chinese medicine composition for O2O line conditioning are as follows:
  • Rhubarb 4 parts, Astragalus: 5 parts, Cork: 16 parts, Wild chrysanthemum: 8 parts, Hedyotis: 16 parts, Raw glutinous rice: 6 parts, Mulberry white: 10 parts, Cassia: 13 parts, Shouwu: 14 parts, Coix seed: 10 parts, Mulberry leaves: 4 parts, saponin: 5 parts, honeysuckle: 7.5 parts, habitat: 9 parts.
  • the components of the acne Chinese medicine composition for O2O line conditioning are as follows:
  • Rhubarb 5 parts, Astragalus: 5 parts, Cork: 16 parts, Wild chrysanthemum: 8 parts, Hedyotis: 16 parts, Raw glutinous rice: 6 parts, Mulberry white: 11 parts, Cassia: 16 parts, Shouwu: 15 parts, Coix seed: 10 parts, Mulberry leaves: 4 parts, saponin: 5 parts, honeysuckle: 7.5 parts, habitat: 9 parts.
  • the components of the acne Chinese medicine composition for O2O line conditioning are as follows:
  • Rhubarb 5 parts, Astragalus: 5 parts, Cork: 15 parts, Wild chrysanthemum: 10 parts, Hedyotis: 16 parts, Raw glutinous rice: 6 parts, Mulberry white: 11 parts, Cassia: 16 parts, Shouwu: 15 parts, Coix seed: 10 parts, Mulberry leaves: 4 parts, saponin: 5 parts, honeysuckle: 7.5 parts, habitat: 9 parts.
  • the components of the acne Chinese medicine composition for O2O line conditioning are as follows:
  • Rhubarb 4 parts, Astragalus: 5 parts, Cork: 16 parts, Wild chrysanthemum: 8 parts, Hedyotis: 16 parts, Raw glutinous rice: 6 parts, Mulberry white: 11 parts, Cassia: 15 parts, Shouwu: 15 parts, Coix seed: 10 parts, Mulberry leaves: 5 parts, saponin: 4 parts, honeysuckle: 7 parts, habitat: 10 parts.
  • the acne traditional Chinese medicine compositions for the O2O offline conditioning in the above Examples 1-15 were prepared by the following methods:
  • Symptoms It has typical clinical manifestations and meets the diagnostic criteria for acne vulgaris and acne. No medication has been given for one month.
  • Cure The clinical symptoms disappear and do not recur within one year.
  • the treatment results taking the drug for a course of treatment in January, the lighter one course of recovery, the severe three courses of healing.
  • the effective rate is 97.3%
  • the cure rate is 89.1%
  • the improvement rate is 6.4%.
  • Case 1 Patient Li Shaodong, male, 16 years old, high school student. In March 2011, the patient started to have acne since junior high school. Usually, he did not pay attention to facial skin hygiene, resulting in more and more acne, many acne marks, symptoms at the time of diagnosis: more acne marks on the face, pox The acne is larger. Taking the prescription of the present invention,
  • Case 2 Patient Miss Cold, 23 years old. In July 2013, due to the high incidence of acne, the secretion of estrogen and androgen was disordered, and the secretion of sebaceous glands was too strong. Symptoms at the time of diagnosis: severe hemorrhoids, redness and swelling of the face, large pores, and severe oily skin.
  • the prescription of the present invention was administered three times a day, and after taking the first month, the size of the acne was obviously improved. After taking three and a half months, the hemorrhoids were completely eliminated, and the problem of skin oil was also significantly improved. After 1.5 years of follow-up, no recurrence was observed.
  • Case 3 Patient Mr. Chen, 35 years old. At the time of consultation in November 2013, the symptoms at the time of visit: facial acne, red papules, pustules for 4 months, cheeks. Diagnosed as acne vulgaris; given the prescription of the present invention, the pustule disappeared after the first week, and the papules decreased; the pimples disappeared in the fourth week, only a little acne; after two and a half months of adherence, the symptoms completely disappeared, and the acne marks It also became very shallow. After 1 year of follow-up, no recurrence was observed.

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Abstract

一种用于O2O线下调理的祛痘中药组合物，由以下原料组成（重量份)：大黄(2-8)，黄芩（2-8)，黄柏(9-17)，野菊花(7-12)，蛇舌草(9-17)，生槐米(2-8)，桑白皮(7-12)，决明子(9-17)，首乌(9-17)，薏仁(7-12)，桑叶(2-8)，皂角刺(2-8)，金银花(5-11)，生地(7-12)。该中药组合物具有清热解毒、祛油脂、消炎和祛除痤疮的功效。

Description

用于O2O线下调理的祛痘中药组合物及其制备方法
技术领域
本发明涉及医学技术领域，尤其涉及一种用于O2O线下调理的祛痘中药组合物及其制备方法。
背景技术
痤疮，又称青春痘，是一种毛囊性皮脂腺单位的慢性炎性病变，痤疮的主要特征是粉刺、脓包、囊肿及瘢痕等。它的诱发与多种因素有关如雄性激素增多、皮脂腺分泌增多、毛囊腺体的过度角化以及炎症有关。目前市场上常见的祛痘药物很多，但是总的来说，西药的价格偏贵，而且副作用很大，而普通中药的药效又很慢，有时治疗还不彻底，留下疤痕，给患者带来很多烦恼，影响患者的身体和心理健康。
发明内容
本发明的目的在于提供一种用于O2O线下调理的祛痘中药组合物及其制备方法，达到清热解毒、祛油脂、消炎和祛除痤疮的功效。
为实现上述目的，本发明提供一种用于O2O线下调理的祛痘中药组合物，所述中药组合物由以下重量份组成：
大黄：2~8份，黄芩：2~8份，黄柏：9~17份，野菊花：7~12份，蛇舌草：9~17份，生槐米：2~8份，桑白皮：7~12份，决明子：9~17份，首乌：9~17份，薏仁：7~12份，桑叶：2~8份，皂角刺：2~8份，金银花：5~11份，生地：7~12份。
优选地，所述中药组合物由以下重量份组成：
大黄：3~5份，黄芩：4~5份，黄柏：15~17份，野菊花：7~10份，蛇舌草：15~17份，生槐米：5~8份，桑白皮：10~12份，决明子：15~17份，首乌：14~16份，薏仁：9~10份，桑叶：4~6份，皂角刺：4~5份，金银花：5~8份，生地：9~10份。
优选地，所述中药组合物由以下重量份组成：
大黄：4份，黄芩：4份，黄柏：15份，野菊花：7份，蛇舌草：15份，生槐米：5份，桑白皮：10份，决明子：15份，首乌：14份，薏仁：10份，桑叶：4份，皂角刺：5份，金银花：5份，生地：10份。
优选地，所述中药组合物由以下重量份组成：
大黄：5份，黄芩：4份，黄柏：15份，野菊花：7份，蛇舌草：15份，生槐米：5份，桑白皮：10份，决明子：15份，首乌：14份，薏仁：10份，桑叶：4份，皂角刺：5份，金银花：5份，生地：10份。
优选地，所述中药组合物由以下重量份组成：
大黄：5份，黄芩：5份，黄柏：16份，野菊花：7份，蛇舌草：15份，生槐米：5份，桑白皮：10份，决明子：15份，首乌：14份，薏仁：10份，桑叶：4份，皂角刺：5份，金银花：5份，生地：10份。
优选地，所述中药组合物由以下重量份组成：
大黄：5份，黄芩：5份，黄柏：16份，野菊花：8份，蛇舌草：16份，生槐米：5份，桑白皮：10份，决明子：15份，首乌：14份，薏仁：10份，桑叶：4份，皂角刺：5份，金银花：5份，生地：10份。
优选地，所述中药组合物由以下重量份组成：
大黄：5份，黄芩：4份，黄柏：16份，野菊花：8份，蛇舌草：16份，生槐米：6份，桑白皮：11份，决明子：15份，首乌：14份，薏仁：9份，桑叶：5份，皂角刺：5份，金银花：5份，生地：10份。
优选地，所述中药组合物由以下重量份组成：
大黄：4份，黄芩：5份，黄柏：16份，野菊花：8份，蛇舌草：16份，生槐米：6份，桑白皮：11份，决明子：15份，首乌：14份，薏仁：10份，桑叶：4份，皂角刺：5份，金银花：7.5份，生地：9份。
优选地，所述中药组合物由以下重量份组成：
大黄：4份，黄芩：5份，黄柏：17份，野菊花：9份，蛇舌草：16份，生槐米：6份，桑白皮：11份，决明子：15份，首乌：14份，薏仁：10份，桑叶：4份，皂角刺：5份，金银花：7.5份，生地：9份。
优选地，所述中药组合物由以下重量份组成：
大黄：4份，黄芩：5份，黄柏：16份，野菊花：10份，蛇舌草：15份，生槐米：6份，桑白皮：11份，决明子：15份，首乌：14份，薏仁：10份，桑叶：4份，皂角刺：5份，金银花：7.5份，生地：9份。
优选地，所述中药组合物由以下重量份组成：
大黄：4份，黄芩：5份，黄柏：15份，野菊花：10份，蛇舌草：15份，生槐米：5份，桑白皮：11份，决明子：15份，首乌：14份，薏仁：10份，桑叶：4份，皂角刺：5份，金银花：7.5份，生地：9份。
优选地，所述中药组合物由以下重量份组成：
大黄：4份，黄芩：5份，黄柏：16份，野菊花：8份，蛇舌草：16份，生槐米：5份，桑白皮：10份，决明子：15份，首乌：14份，薏仁：10份，桑叶：4份，皂角刺：5份，金银花：7.5份，生地：9份。
优选地，所述中药组合物由以下重量份组成：
大黄：4份，黄芩：5份，黄柏：16份，野菊花：8份，蛇舌草：16份，生槐米：6份，桑白皮：10份，决明子：13份，首乌：14份，薏仁：10份，桑叶：4份，皂角刺：5份，金银花：7.5份，生地：9份。
优选地，所述中药组合物由以下重量份组成：
大黄：5份，黄芩：5份，黄柏：16份，野菊花：8份，蛇舌草：16份，生槐米：6份，桑白皮：11份，决明子：16份，首乌：15份，薏仁：10份，桑叶：4份，皂角刺：5份，金银花：7.5份，生地：9份。
此外，为实现上述目的，本发明还提供一种用于O2O线下调理的祛痘中药组合物的制备方法，所述制备方法包含以下步骤：
A、将大黄、黄芩、黄柏、野菊花、蛇舌草、生槐米、桑白皮、决明子、首乌、薏仁、桑叶、皂角刺、金银花、生地、加入8-10倍体积的水浸泡40分钟后煎煮，水开后煎煮35-40分钟，倒出煎液AA；
B、向煎液AA中加入3-4倍体积的水，煎煮 15-25分钟，倒出煎液BB；
C、将煎液AA和煎液BB混匀，静置澄清10-15分钟，吸取上清液，过滤形成滤液CC备用；将所述煎液CC分装于洁净干燥灭菌的大口容器中，冷却后加盖密闭备用。
本发明以大黄、黄芩、黄柏、野菊花、蛇舌草、生槐米、桑白皮、决明子、首乌、薏仁、桑叶、皂角刺、金银花、生地为药物中各组份，通过它们协同作用起到清热解毒，祛油脂，消炎，祛除痤疮的功效，对祛痘有很好的治疗效果，使皮肤细腻白嫩，富有光泽，改善了使用者的皮肤健康。
具体实施方式
下面结合具体实施例对本发明做进一步的详细说明，以下实施例是对本发明的解释，本发明并不局限于以下实施例。
本发明提供的用于O2O线下调理的祛痘中药组合物，所述中药组合物由以下重量份组成：
大黄：2~8份，黄芩：2~8份，黄柏：9~17份，野菊花：7~12份，蛇舌草：9~17份，生槐米：2~8份，桑白皮：7~12份，决明子：9~17份，首乌：9~17份，薏仁：7~12份，桑叶：2~8份，皂角刺：2~8份，金银花：5~11份，生地：7~12份。
在上述组份中，大黄：具有攻积滞、清湿热、泻火凉血和祛瘀解毒功效；用于实热便秘、积滞腹痛、泻痢不爽、湿热黄疸等症。
黄芩：具有清热燥湿、凉血解毒功效；用于痈肿疖疮、温热病、湿热黄胆、目赤等症。
黄柏：具有清热、泻火、燥湿、解毒的功效；用于疮疡肿毒、湿热泻痢、和湿疹瘙痒等症。
野菊花：味苦、辛，性平；归肺、肝经；具有清热解毒、疏风平肝功效；用于疔疮、痈疽、皮炎、丹毒、湿疹的治疗。
蛇舌草：具有清热解毒、消痛散结和利尿除湿功效；用于疮疖肿痛、肠痈肺痈、毒蛇咬伤。蛇舌草还可用于湿热水肿、热淋、黄疸等症。
生槐米：性微寒，味苦；具有凉血止血，清肝泻火功效；用于肝热目赤、头痛眩晕。
桑白皮：具有利水消肿、泻肺平喘功效；用于面目浮肿、小便不利等症。
有修复受损组织细胞、淡化疤痕、利水消肿之功效；此外桑白皮还有降压作用。
决明子是决明结的种子，具有清肝明目、通便的功效；决明子在生活中有很多种用途，尤其是对眼胀酸痛有很好的缓解效果，于治疗目赤肿痛、眼睛酸涩、易流泪。这主要是由于肝火太旺导致的，决明子可以清泄肝胆郁火，常与龙胆草、黄芩、夏枯草等同用。还可用于高血压病而呈现肝阳上扰、头晕目眩等症候者。决明子可以使淤积在体内的肝火下降，使体内阴阳调和，可以通顺大便，解决大便干燥的问题。现代药理研究证实，决明子所含的有效成分具有调节免疫、抑菌、抗癌、降血压、调节血脂及明目通便等作用。对金黄色葡萄球菌、大肠杆菌、肺炎球菌等均有不同程度的抑制作用；通过作用于迷走神经有降压效果，可与传统降压药利血平相媲美；通过导泻可减少肠道对胆固醇的吸收，并能反馈调节低密度脂蛋白的代谢；能防治近视眼及老年性白内障等眼科疾病。
首乌：具有补肝肾、益精血、乌须发和强筋骨功效；用于精血亏虚，头晕眼花，须发早白，腰酸脚软等证。此外还可以促进造血功能增强免疫功能 降血脂与抗动脉粥样硬化，延缓衰老，现代调查首乌含有维生素E，阻止皱纹再生。此外首乌具有调节内分泌和润肠通便的功能。
薏仁：味甘、淡、性微寒、归脾、胃、肺经；具有健脾利水、利湿除痹、清热排脓、清利湿热之功效；可用于治疗水肿、泄泻、筋脉拘挛、屈伸不利、、脚气等症。
桑叶：具有疏散风热、清肺润燥、清肝明目功效；用于风热感冒、肺热燥咳、头晕头痛、目赤昏花。此外桑叶还具有去热的功效，能够消除眼部疲劳、消肿、清血，养颜、抗衰老、祛斑，治疗痢疾、浮肿、补肝等功能。近年的研究成果证实：桑叶、桑白皮萃取通过抑制酪氨酸酶之活性，有效减少黑色素生成，温和有效，自然美白。
皂角刺：辛，温，无毒；具有消肿排脓、消毒透脓、搜风、杀虫的功效；用于消肿排脓、祛风杀虫。用于痈疽疮毒初起、脓成不溃之症以及皮癣、麻风等症状。
金银花：性寒，具有清热解毒、疏散风热的功效；用于清热解毒、疏利咽喉、消暑除烦。可治疗疮疖肿毒、暑热症、泻痢、流感、急慢性扁桃体炎、牙周炎等病。金银花的作用除药用外，其美容、减肥和保健养生的作用更为神奇，金银花具有清除体内有毒物质，降脂、减肥、对身体所起到的巨大保护和修复作用。
生地：性凉，味甘，入心、肝、肾经，具有清热滋阴、凉血止血、生津止渴的功效；现代药理研究表明，地黄具有抗辐射、保肝、降低血糖、强心、止血、利尿、抗真菌的作用。
服用上述药物，大黄能够有效改善实热便秘、湿热黄疸等症，有助于清湿热、泻火、凉血、祛瘀、解毒；黄芩有助于清热燥湿，凉血，解毒，能够有效改善痈肿疖疮、温热病等症；黄柏有助于清热、泻火、燥湿、解毒，能够有效改善疮疡肿毒，湿热泻痢，湿疹瘙痒等症；野菊花有助于清热解毒、疏风平肝，能够有效改善疔疮、痈疽、皮炎、丹毒、湿疹等症；蛇舌草有助于清热解毒、消痛散结、利尿除湿，能够有效改善疮疖肿痛、肠痈、肺痈、毒蛇咬伤等症；生槐米有助于凉血止血、清肝泻火、能够有效改善肝热目赤、头痛眩晕等症；桑白皮有助于利水消肿、泻肺平喘，能够有效改善面目浮肿、小便不利等症，有修复受损组织细胞，淡化疤痕，利水消肿之功效；此外还有降压作用；决明子有助于清肝明目、通便，能够有效改善治疗目赤肿痛、眼睛酸涩、易流泪等症；首乌有助于补肝肾、益精血，能够有效改善造血功能增强免疫功能、降血脂与抗动脉粥样硬化等症；薏仁有助于健脾利水、利湿除痹、清热排脓、清利湿热，能够有效改善水肿、泄泻、筋脉拘挛、屈伸不利、脚气等症；桑叶有助于疏散风热、清肺润燥、清肝明目，能够有效改善去热、头晕眼花、消肿、清血，养颜、美白和祛斑等症；皂角刺有助于消肿排脓、消毒透脓、搜风、杀虫，能够有效改善消肿排脓、痈疽疮毒初起或脓成不溃之症以及皮癣、麻风等症；金银花有助于清热解毒、疏散风热、降脂，能够有效改善清热解毒、疮疖肿毒等症；生地有助于清热滋阴、凉血止血、生津止渴，具有抗辐射、保肝、降低血糖、强心、止血、利尿、抗真菌的作用。通过上述药物组份的协同作用起到清热解毒，祛油脂，消炎，祛除痤疮的功效，对祛痘有很好的治疗效果，使皮肤细腻白嫩，富有光泽，改善了使用者的健康。
实施例1
用于O2O线下调理的祛痘中药组合物的组分如下：
大黄：3~5份，黄芩：4~5份，黄柏：15~17份，野菊花：7~10份，蛇舌草：15~17份，生槐米：5~8份，桑白皮：10~12份，决明子：15~17份，首乌：14~16份，薏仁：9~10份，桑叶：4~6份，皂角刺：4~5份，金银花：5~8份，生地：9~10份。
实施例2
用于O2O线下调理的祛痘中药组合物的组分如下：
大黄：4份，黄芩：4份，黄柏：15份，野菊花：7份，蛇舌草：15份，生槐米：5份，桑白皮：10份，决明子：15份，首乌：14份，薏仁：10份，桑叶：4份，皂角刺：5份，金银花：5份，生地：10份。
实施例3
用于O2O线下调理的祛痘中药组合物的组分如下：
大黄：5份，黄芩：4份，黄柏：15份，野菊花：7份，蛇舌草：15份，生槐米：5份，桑白皮：10份，决明子：15份，首乌：14份，薏仁：10份，桑叶：4份，皂角刺：5份，金银花：5份，生地：10份。
实施例4
用于O2O线下调理的祛痘中药组合物的组分如下：
大黄：5份，黄芩：5份，黄柏：16份，野菊花：7份，蛇舌草：15份，生槐米：5份，桑白皮：10份，决明子：15份，首乌：14份，薏仁：10份，桑叶：4份，皂角刺：5份，金银花：5份，生地：10份。
实施例5
用于O2O线下调理的祛痘中药组合物的组分如下：
大黄：5份，黄芩：5份，黄柏：16份，野菊花：8份，蛇舌草：16份，生槐米：5份，桑白皮：10份，决明子：15份，首乌：14份，薏仁：10份，桑叶：4份，皂角刺：5份，金银花：5份，生地：10份。
实施例6
用于O2O线下调理的祛痘中药组合物的组分如下：
大黄：5份，黄芩：4份，黄柏：16份，野菊花：8份，蛇舌草：16份，生槐米：6份，桑白皮：11份，决明子：15份，首乌：14份，薏仁：9份，桑叶：5份，皂角刺：5份，金银花：5份，生地：10份。
实施例7
用于O2O线下调理的祛痘中药组合物的组分如下：
大黄：4份，黄芩：5份，黄柏：16份，野菊花：8份，蛇舌草：16份，生槐米：6份，桑白皮：11份，决明子：15份，首乌：14份，薏仁：10份，桑叶：4份，皂角刺：5份，金银花：7.5份，生地：9份。
实施例8
用于O2O线下调理的祛痘中药组合物的组分如下：
大黄：4份，黄芩：5份，黄柏：17份，野菊花：9份，蛇舌草：16份，生槐米：6份，桑白皮：11份，决明子：15份，首乌：14份，薏仁：10份，桑叶：4份，皂角刺：5份，金银花：7.5份，生地：9份。
实施例9
用于O2O线下调理的祛痘中药组合物的组分如下：
大黄：4份，黄芩：5份，黄柏：16份，野菊花：10份，蛇舌草：15份，生槐米：6份，桑白皮：11份，决明子：15份，首乌：14份，薏仁：10份，桑叶：4份，皂角刺：5份，金银花：7.5份，生地：9份。
实施例10
用于O2O线下调理的祛痘中药组合物的组分如下：
大黄：4份，黄芩：5份，黄柏：15份，野菊花：10份，蛇舌草：15份，生槐米：5份，桑白皮：11份，决明子：15份，首乌：14份，薏仁：10份，桑叶：4份，皂角刺：5份，金银花：7.5份，生地：9份。
实施例11
用于O2O线下调理的祛痘中药组合物的组分如下：
大黄：4份，黄芩：5份，黄柏：16份，野菊花：8份，蛇舌草：16份，生槐米：5份，桑白皮：10份，决明子：15份，首乌：14份，薏仁：10份，桑叶：4份，皂角刺：5份，金银花：7.5份，生地：9份。
实施例12
用于O2O线下调理的祛痘中药组合物的组分如下：
大黄：4份，黄芩：5份，黄柏：16份，野菊花：8份，蛇舌草：16份，生槐米：6份，桑白皮：10份，决明子：13份，首乌：14份，薏仁：10份，桑叶：4份，皂角刺：5份，金银花：7.5份，生地：9份。
实施例13
用于O2O线下调理的祛痘中药组合物的组分如下：
大黄：5份，黄芩：5份，黄柏：16份，野菊花：8份，蛇舌草：16份，生槐米：6份，桑白皮：11份，决明子：16份，首乌：15份，薏仁：10份，桑叶：4份，皂角刺：5份，金银花：7.5份，生地：9份。
实施例14
用于O2O线下调理的祛痘中药组合物的组分如下：
大黄：5份，黄芩：5份，黄柏：15份，野菊花：10份，蛇舌草：16份，生槐米：6份，桑白皮：11份，决明子：16份，首乌：15份，薏仁：10份，桑叶：4份，皂角刺：5份，金银花：7.5份，生地：9份。
实施例15
用于O2O线下调理的祛痘中药组合物的组分如下：
大黄：4份，黄芩：5份，黄柏：16份，野菊花：8份，蛇舌草：16份，生槐米：6份，桑白皮：11份，决明子：15份，首乌：15份，薏仁：10份，桑叶：5份，皂角刺：4份，金银花：7份，生地：10份。
以上实施例1-15中的用于O2O线下调理的祛痘中药组合物均采用下述方法制备：
A、将大黄、黄芩、黄柏、野菊花、蛇舌草、生槐米、桑白皮、决明子、首乌、薏仁、桑叶、皂角刺、金银花、生地、加入8-10倍体积的水浸泡40分钟后煎煮，水开后煎煮35-40分钟，倒出煎液AA；
B、向煎液AA中加入3-4倍体积的水，煎煮 15-25分钟，倒出煎液BB；
C、将煎液AA和煎液BB混匀，静置澄清10-15分钟，吸取上清液，过滤形成滤液CC备用；将所述煎液CC分装于洁净干燥灭菌的大口容器中，冷却后加盖密闭备用。
临床疗效总结：
一、一般资料：共治疗病人48例，其中男性15 例，女性33例；年龄13-18岁23 例，19-27岁17例，27岁以上8 例；病程最长者14 年，最短者5个月。
二、诊断标准：
症状：具有典型的临床表现，符合寻常性痤疮、青春痘的诊断标准，一个月内未做任何药物治疗。
三、疗效评定标准：
1、治愈：临床症状消失，一年内不复发。
2、好转：临床症状减轻，发作次数明显减少。
四、治疗结果：服药一月为一疗程，轻者一疗程痊愈，重者三疗程痊愈。有效率97.3%，治愈率89.1%，好转率6.4%。
五、典型病例：
病例1：患者李少东，男，16岁，高二学生。2011年3月来诊，患者自初中就开始长青春痘，平时没有注意脸部皮肤卫生，导致痘痘越来越多，痘印很多，来诊时的症状：脸部痘印较多，痘痘较大颗。给予本发明方药服用，
每日三次，服用第一周后，痘痘明显变小，较大颗痘痘变干瘪，颜色淡了一些。服用三个月，痘痘彻底消除，痘印也彻底祛除。随访3年，未见复发。
病例2：患者冷小姐，23岁。2013年7月来诊，由于处于痤疮高发的年纪，雌雄激素分泌失调，皮脂腺分泌过旺，来诊时的症状：痤疮严重，脸部红肿，毛孔粗大，皮肤出油严重。给予本发明方药服用，每日三次，服用第一月后，明显改善痘痘的大小，坚持服用三个半月后，痤疮彻底消除，皮肤出油问题也明显改善。随访1.5年，未见复发。
病例3：患者陈先生，35岁。2013年11月来诊，来诊时的症状：面部起粉刺、红色丘疹、脓疱4个月，双颊为著。诊断为寻常性痤疮；给予本发明方药服用，服用第1周后脓疱消失，丘疹减少；第4周丘疹全部消失，只有少许的粉刺；坚持服用两个半月后，症状完全消失，且痘印也变得很浅。随访1年，未见复发。
上述病例证明该方具有祛油脂，消炎，祛除痤疮的功效，使皮肤细腻白嫩，富有光泽，改善了使用者的皮肤健康，给使用者带来了自信和美丽。
以上仅为本发明的优选实施例，并非因此限制本发明的专利范围，凡是利用本发明说明书所作的等效结构或等效流程变换，或直接或间接运用在其他相关的技术领域，均同理包括在本发明的专利保护范围内。

Claims (15)

  1. 一种用于O2O线下调理的祛痘中药组合物，其特征在于，所述中药组合物由以下重量份组成：
    大黄：2~8份，黄芩：2~8份，黄柏：9~17份，野菊花：7~12份，蛇舌草：9~17份，生槐米：2~8份，桑白皮：7~12份，决明子：9~17份，首乌：9~17份，薏仁：7~12份，桑叶：2~8份，皂角刺：2~8份，金银花：5~11份，生地：7~12份。
  2. 如权利要求1所述的用于O2O线下调理的祛痘中药组合物，其特征在于，所述中药组合物由以下重量份组成：
    大黄：3~5份，黄芩：4~5份，黄柏：15~17份，野菊花：7~10份，蛇舌草：15~17份，生槐米：5~8份，桑白皮：10~12份，决明子：15~17份，首乌：14~16份，薏仁：9~10份，桑叶：4~6份，皂角刺：4~5份，金银花：5~8份，生地：9~10份。
  3. 如权利要求1所述的用于O2O线下调理的祛痘中药组合物，其特征在于，所述中药组合物由以下重量份组成：
    大黄：4份，黄芩：4份，黄柏：15份，野菊花：7份，蛇舌草：15份，生槐米：5份，桑白皮：10份，决明子：15份，首乌：14份，薏仁：10份，桑叶：4份，皂角刺：5份，金银花：5份，生地：10份。
  4. 如权利要求1所述的用于O2O线下调理的祛痘中药组合物，其特征在于，所述中药组合物由以下重量份组成：
    大黄：5份，黄芩：4份，黄柏：15份，野菊花：7份，蛇舌草：15份，生槐米：5份，桑白皮：10份，决明子：15份，首乌：14份，薏仁：10份，桑叶：4份，皂角刺：5份，金银花：5份，生地：10份。
  5. 如权利要求1所述的用于O2O线下调理的祛痘中药组合物，其特征在于，所述中药组合物由以下重量份组成：
    大黄：5份，黄芩：5份，黄柏：16份，野菊花：7份，蛇舌草：15份，生槐米：5份，桑白皮：10份，决明子：15份，首乌：14份，薏仁：10份，桑叶：4份，皂角刺：5份，金银花：5份，生地：10份。
  6. 如权利要求1所述的用于O2O线下调理的祛痘中药组合物，其特征在于，所述中药组合物由以下重量份组成：
    大黄：5份，黄芩：5份，黄柏：16份，野菊花：8份，蛇舌草：16份，生槐米：5份，桑白皮：10份，决明子：15份，首乌：14份，薏仁：10份，桑叶：4份，皂角刺：5份，金银花：5份，生地：10份。
  7. 如权利要求1所述的用于O2O线下调理的祛痘中药组合物，其特征在于，所述中药组合物由以下重量份组成：
    大黄：5份，黄芩：4份，黄柏：16份，野菊花：8份，蛇舌草：16份，生槐米：6份，桑白皮：11份，决明子：15份，首乌：14份，薏仁：9份，桑叶：5份，皂角刺：5份，金银花：5份，生地：10份。
  8. 如权利要求1所述的用于O2O线下调理的祛痘中药组合物，其特征在于，所述中药组合物由以下重量份组成：
    大黄：4份，黄芩：5份，黄柏：16份，野菊花：8份，蛇舌草：16份，生槐米：6份，桑白皮：11份，决明子：15份，首乌：14份，薏仁：10份，桑叶：4份，皂角刺：5份，金银花：7.5份，生地：9份。
  9. 如权利要求1所述的用于O2O线下调理的祛痘中药组合物，其特征在于，所述中药组合物由以下重量份组成：
    大黄：4份，黄芩：5份，黄柏：17份，野菊花：9份，蛇舌草：16份，生槐米：6份，桑白皮：11份，决明子：15份，首乌：14份，薏仁：10份，桑叶：4份，皂角刺：5份，金银花：7.5份，生地：9份。
  10. 如权利要求1所述的用于O2O线下调理的祛痘中药组合物，其特征在于，所述中药组合物由以下重量份组成：
    大黄：4份，黄芩：5份，黄柏：16份，野菊花：10份，蛇舌草：15份，生槐米：6份，桑白皮：11份，决明子：15份，首乌：14份，薏仁：10份，桑叶：4份，皂角刺：5份，金银花：7.5份，生地：9份。
  11. 如权利要求1所述的用于O2O线下调理的祛痘中药组合物，其特征在于，所述中药组合物由以下重量份组成：
    大黄：4份，黄芩：5份，黄柏：15份，野菊花：10份，蛇舌草：15份，生槐米：5份，桑白皮：11份，决明子：15份，首乌：14份，薏仁：10份，桑叶：4份，皂角刺：5份，金银花：7.5份，生地：9份。
  12. 如权利要求1所述的用于O2O线下调理的祛痘中药组合物，其特征在于，所述中药组合物由以下重量份组成：
    大黄：4份，黄芩：5份，黄柏：16份，野菊花：8份，蛇舌草：16份，生槐米：5份，桑白皮：10份，决明子：15份，首乌：14份，薏仁：10份，桑叶：4份，皂角刺：5份，金银花：7.5份，生地：9份。
  13. 如权利要求1所述的用于O2O线下调理的祛痘中药组合物，其特征在于，所述中药组合物由以下重量份组成：
    大黄：4份，黄芩：5份，黄柏：16份，野菊花：8份，蛇舌草：16份，生槐米：6份，桑白皮：10份，决明子：13份，首乌：14份，薏仁：10份，桑叶：4份，皂角刺：5份，金银花：7.5份，生地：9份。
  14. 如权利要求1所述的用于O2O线下调理的祛痘中药组合物，其特征在于，所述中药组合物由以下重量份组成：
    大黄：5份，黄芩：5份，黄柏：16份，野菊花：8份，蛇舌草：16份，生槐米：6份，桑白皮：11份，决明子：16份，首乌：15份，薏仁：10份，桑叶：4份，皂角刺：5份，金银花：7.5份，生地：9份。
  15. 一种如权利要求1所述的用于O2O线下调理的祛痘中药组合物的制备方法，其特征在于，所述制备方法包含以下步骤：
    A、将大黄、黄芩、黄柏、野菊花、蛇舌草、生槐米、桑白皮、决明子、首乌、薏仁、桑叶、皂角刺、金银花、生地、加入8-10倍体积的水浸泡40分钟后煎煮，水开后煎煮35-40分钟，倒出煎液AA；
    B、向煎液AA中加入3-4倍体积的水，煎煮 15-25分钟，倒出煎液BB；
    C、将煎液AA和煎液BB混匀，静置澄清10-15分钟，吸取上清液，过滤形成滤液CC备用；将所述煎液CC分装于洁净干燥灭菌的大口容器中，冷却后加盖密闭备用。
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