WO2016088155A1 - 粒子線ビーム調整装置及び方法、粒子線治療装置 - Google Patents
粒子線ビーム調整装置及び方法、粒子線治療装置 Download PDFInfo
- Publication number
- WO2016088155A1 WO2016088155A1 PCT/JP2014/006068 JP2014006068W WO2016088155A1 WO 2016088155 A1 WO2016088155 A1 WO 2016088155A1 JP 2014006068 W JP2014006068 W JP 2014006068W WO 2016088155 A1 WO2016088155 A1 WO 2016088155A1
- Authority
- WO
- WIPO (PCT)
- Prior art keywords
- particle beam
- axis
- particle
- irradiation
- monitor
- Prior art date
Links
Images
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
- A61N5/00—Radiation therapy
- A61N5/10—X-ray therapy; Gamma-ray therapy; Particle-irradiation therapy
- A61N5/1048—Monitoring, verifying, controlling systems and methods
- A61N5/1064—Monitoring, verifying, controlling systems and methods for adjusting radiation treatment in response to monitoring
- A61N5/1065—Beam adjustment
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
- A61N5/00—Radiation therapy
- A61N5/10—X-ray therapy; Gamma-ray therapy; Particle-irradiation therapy
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
- A61N5/00—Radiation therapy
- A61N5/10—X-ray therapy; Gamma-ray therapy; Particle-irradiation therapy
- A61N5/1042—X-ray therapy; Gamma-ray therapy; Particle-irradiation therapy with spatial modulation of the radiation beam within the treatment head
- A61N5/1043—Scanning the radiation beam, e.g. spot scanning or raster scanning
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
- A61N5/00—Radiation therapy
- A61N5/10—X-ray therapy; Gamma-ray therapy; Particle-irradiation therapy
- A61N5/1048—Monitoring, verifying, controlling systems and methods
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
- A61N5/00—Radiation therapy
- A61N5/10—X-ray therapy; Gamma-ray therapy; Particle-irradiation therapy
- A61N5/1048—Monitoring, verifying, controlling systems and methods
- A61N5/1064—Monitoring, verifying, controlling systems and methods for adjusting radiation treatment in response to monitoring
- A61N5/1065—Beam adjustment
- A61N5/1067—Beam adjustment in real time, i.e. during treatment
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
- A61N5/00—Radiation therapy
- A61N5/10—X-ray therapy; Gamma-ray therapy; Particle-irradiation therapy
- A61N5/1048—Monitoring, verifying, controlling systems and methods
- A61N5/1075—Monitoring, verifying, controlling systems and methods for testing, calibrating, or quality assurance of the radiation treatment apparatus
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
- A61N5/00—Radiation therapy
- A61N5/10—X-ray therapy; Gamma-ray therapy; Particle-irradiation therapy
- A61N5/1077—Beam delivery systems
-
- G—PHYSICS
- G21—NUCLEAR PHYSICS; NUCLEAR ENGINEERING
- G21K—TECHNIQUES FOR HANDLING PARTICLES OR IONISING RADIATION NOT OTHERWISE PROVIDED FOR; IRRADIATION DEVICES; GAMMA RAY OR X-RAY MICROSCOPES
- G21K1/00—Arrangements for handling particles or ionising radiation, e.g. focusing or moderating
- G21K1/08—Deviation, concentration or focusing of the beam by electric or magnetic means
- G21K1/093—Deviation, concentration or focusing of the beam by electric or magnetic means by magnetic means
-
- G—PHYSICS
- G21—NUCLEAR PHYSICS; NUCLEAR ENGINEERING
- G21K—TECHNIQUES FOR HANDLING PARTICLES OR IONISING RADIATION NOT OTHERWISE PROVIDED FOR; IRRADIATION DEVICES; GAMMA RAY OR X-RAY MICROSCOPES
- G21K5/00—Irradiation devices
- G21K5/04—Irradiation devices with beam-forming means
-
- H—ELECTRICITY
- H05—ELECTRIC TECHNIQUES NOT OTHERWISE PROVIDED FOR
- H05H—PLASMA TECHNIQUE; PRODUCTION OF ACCELERATED ELECTRICALLY-CHARGED PARTICLES OR OF NEUTRONS; PRODUCTION OR ACCELERATION OF NEUTRAL MOLECULAR OR ATOMIC BEAMS
- H05H7/00—Details of devices of the types covered by groups H05H9/00, H05H11/00, H05H13/00
- H05H7/001—Arrangements for beam delivery or irradiation
-
- H—ELECTRICITY
- H05—ELECTRIC TECHNIQUES NOT OTHERWISE PROVIDED FOR
- H05H—PLASMA TECHNIQUE; PRODUCTION OF ACCELERATED ELECTRICALLY-CHARGED PARTICLES OR OF NEUTRONS; PRODUCTION OR ACCELERATION OF NEUTRAL MOLECULAR OR ATOMIC BEAMS
- H05H7/00—Details of devices of the types covered by groups H05H9/00, H05H11/00, H05H13/00
- H05H7/04—Magnet systems, e.g. undulators, wigglers; Energisation thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
- A61N5/00—Radiation therapy
- A61N5/10—X-ray therapy; Gamma-ray therapy; Particle-irradiation therapy
- A61N2005/1085—X-ray therapy; Gamma-ray therapy; Particle-irradiation therapy characterised by the type of particles applied to the patient
- A61N2005/1087—Ions; Protons
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
- A61N5/00—Radiation therapy
- A61N5/10—X-ray therapy; Gamma-ray therapy; Particle-irradiation therapy
- A61N2005/1092—Details
- A61N2005/1094—Shielding, protecting against radiation
-
- H—ELECTRICITY
- H05—ELECTRIC TECHNIQUES NOT OTHERWISE PROVIDED FOR
- H05H—PLASMA TECHNIQUE; PRODUCTION OF ACCELERATED ELECTRICALLY-CHARGED PARTICLES OR OF NEUTRONS; PRODUCTION OR ACCELERATION OF NEUTRAL MOLECULAR OR ATOMIC BEAMS
- H05H7/00—Details of devices of the types covered by groups H05H9/00, H05H11/00, H05H13/00
- H05H7/001—Arrangements for beam delivery or irradiation
- H05H2007/002—Arrangements for beam delivery or irradiation for modifying beam trajectory, e.g. gantries
-
- H—ELECTRICITY
- H05—ELECTRIC TECHNIQUES NOT OTHERWISE PROVIDED FOR
- H05H—PLASMA TECHNIQUE; PRODUCTION OF ACCELERATED ELECTRICALLY-CHARGED PARTICLES OR OF NEUTRONS; PRODUCTION OR ACCELERATION OF NEUTRAL MOLECULAR OR ATOMIC BEAMS
- H05H7/00—Details of devices of the types covered by groups H05H9/00, H05H11/00, H05H13/00
- H05H7/04—Magnet systems, e.g. undulators, wigglers; Energisation thereof
- H05H2007/048—Magnet systems, e.g. undulators, wigglers; Energisation thereof for modifying beam trajectory, e.g. gantry systems
Definitions
- Embodiments of the present invention relate to a particle beam beam adjustment apparatus and method for adjusting the trajectory of a particle beam such as carbon or proton with respect to an irradiation target, and a particle beam therapy apparatus using the particle beam beam adjustment apparatus.
- a particle beam therapy system is used to irradiate an affected part of a cancer patient with a particle beam (hereinafter, also simply referred to as a beam) of carbon or protons.
- a particle beam hereinafter, also simply referred to as a beam
- Currently used particle beam irradiation methods include an expanded beam method that expands the diameter of the beam beyond the size of the affected area of a cancer patient. Strictly speaking, this expanded beam method cannot accurately match the shape of the affected part three-dimensionally, so there is a limit to reducing the influence on normal cells around the affected part.
- a scanning irradiation method is being operated in which the affected part of a patient is virtually cut into a three-dimensional lattice to perform irradiation.
- this scanning irradiation method for example, there is a three-dimensional irradiation method called a spot scanning irradiation method.
- this spot scanning irradiation method each spot (point) is irradiated as follows.
- the scanning control device When a predetermined dose is irradiated to a certain spot in the affected area, the scanning control device obtains a dose expiration signal from the dose monitor and outputs a spot switching command signal. Based on this spot switching command signal, the beam extraction control device stops beam extraction.
- the electromagnet power source for supplying the excitation current to the irradiation field forming electromagnet that scans the beam starts setting the current value corresponding to the coordinates of the next irradiation spot.
- the scanning control device acquires a completion signal for setting the current value of the electromagnet power source, it outputs a beam start command signal to the beam extraction control device, and irradiation is started on the next spot. This is sequentially repeated to irradiate the treatment site with respect to one irradiation slice.
- the beam emission is temporarily stopped, the energy of the beam emitted from the accelerator is changed, or the range adjustment device called a range shifter is controlled to control the beam traveling direction. Change the beam stop trajectory (slice). By sequentially performing scanning irradiation and slice switching in this way, beam irradiation over the entire treatment site is performed.
- a position monitor is provided at the irradiation port in order to confirm that the beam is irradiated at the correct position.
- an abnormality occurs in the current setting of the electromagnet power source that causes the excitation current to flow through the irradiation field forming electromagnet, or a beam trajectory shifts from the upstream accelerator to the downstream scanning irradiation device in the beam transport direction, it is predetermined.
- the irradiation trajectory is different from the trajectory measured by the position monitor.
- an interlock signal (emergency stop signal) is output from the position monitor control device provided in the scanning control device, and the treatment irradiation is interrupted.
- the set value of the operating device for operating the beam is corrected every morning while checking the beam trajectory for each set energy of the irradiation beam, and the treatment of the day The beam quality to be used is confirmed.
- a pair of screen monitors on which a fluorescent film is formed on the beam trajectory are arranged at a predetermined distance.
- the beam trajectory can be corrected by adjusting the current value of the correction electromagnet based on the beam trajectory deviation calculated from the output values of these screen monitors (deviation from the ideal center trajectory without beam trajectory deviation).
- the setting values of the operating device for operating the beam are the same, for example, the amount of deviation of the beam trajectory in the morning and the amount of deviation of the beam trajectory in the afternoon are not always the same due to a temperature change or the like. Absent. For this reason, if irradiation of the beam position is detected by the position monitor at the start of irradiation or during irradiation, treatment irradiation may not be completed.
- Patent Document 1 includes a first beam position monitor that detects a beam passing position upstream of the irradiation nozzle and a second beam position monitor that detects a beam passing position downstream of the irradiation nozzle. It is a thing.
- a pair of screen monitors are arranged outside the treatment room, and the beam trajectory is corrected in a trajectory that is far from the trajectory with respect to the patient.
- the distance between the downstream screen monitor and the patient becomes larger than the distance of the screen monitor, and the obtained beam trajectory accuracy is limited.
- the treatment irradiation will be interrupted by detecting the deviation with the position monitor.
- the position monitor detects a beam misalignment during treatment irradiation, the beam trajectory can be corrected without retracting the patient from the irradiation position when treatment is interrupted.
- a beam block large enough to close the beam inlet is installed.
- a pair of the screen monitors are arranged on the upstream side of the beam block in the beam transport direction.
- the screen monitor cannot accurately confirm the deviation of the beam axis unless it is arranged at a predetermined distance.
- the pair of screen monitors When a pair of screen monitors are arranged upstream in the beam transport direction of the large beam block as described above, the pair of screen monitors can be arranged at a predetermined distance from the restriction of the overall size of the apparatus. It may disappear. For this reason, it is impossible to accurately confirm the deviation of the beam axis, and there is a problem that the deviation of the beam axis cannot be adjusted with high accuracy.
- the problem to be solved by the embodiment is to provide a particle beam beam adjustment apparatus and method, and a particle beam therapy apparatus capable of improving the accuracy of the beam trajectory.
- a particle beam beam adjusting apparatus includes a position monitor that detects a positional deviation of a particle beam transported from a beam transport unit, and a position and an angle of an axis of the particle beam.
- a correction electromagnet that adjusts the magnetic field based on a signal indicating the position and angle of the axis of the particle beam beam measured by the screen monitor and adjusts the axis of the particle beam beam;
- a beam scanning electromagnet for irradiating the irradiation target with the particle beam, wherein one of the paired screen monitors is installed outside the treatment room, and the other of the screen monitors is installed in the treatment room.
- the particle beam beam adjusting apparatus includes a position monitor that detects a positional deviation of the particle beam transported from a beam transport unit, a beam scanning electromagnet that irradiates an irradiation target with the particle beam, and the particle A beam block that stops the particle beam reaching the irradiation target in the treatment room when adjusting the axis of the beam, and the beam block is installed in the treatment room.
- the particle beam adjustment method includes a beam misalignment detection step of detecting a misalignment of the particle beam beam transported from the beam transport unit, and the position and angle of the particle beam beam axis outside the treatment room.
- a magnetic field is adjusted based on a measurement process measured by one installed screen monitor and the other screen monitor installed in the treatment room, and an axis position and angle of the particle beam beam measured in the measurement process
- a beam axis adjusting step for adjusting the axis of the particle beam.
- a particle beam therapy system includes a beam generation unit that generates a particle beam, a beam emission control device that controls emission of the particle beam, and a beam that transports the particle beam to an irradiation target in a treatment room Measured by the transport unit, a position monitor for detecting the positional deviation of the particle beam transported from the beam transport unit, a pair of screen monitors for measuring the position and angle of the axis of the particle beam, and the screen monitor A correction electromagnet that adjusts a magnetic field based on a signal indicating the position and angle of the axis of the particle beam, and a beam scanning electromagnet that irradiates the irradiation target with the particle beam; And one of the paired screen monitors is installed outside the treatment room, and the other of the screen monitors is installed in the treatment room. And butterflies.
- the accuracy of the beam trajectory can be improved.
- FIG. 1 is a schematic plan view showing the overall configuration of a particle beam therapy system to which the embodiment is applied.
- FIG. 2 is a block diagram showing the configuration of the irradiation device section and related devices in FIG.
- the particle beam therapy system includes a beam generation unit 10, a beam emission control unit 20, a beam transport unit 30, an irradiation device unit 40 having main components of the present embodiment, and a treatment.
- a chamber 50 is provided.
- the beam generator 10 includes an ion source (not shown), a beam incident system 11, and a circular accelerator 12.
- the irradiation device section 40 includes a horizontal correction electromagnet 51, a horizontal correction electromagnet power supply 51a, a vertical correction electromagnet 52, a vertical correction electromagnet power supply 52a, a screen monitor 61, a power supply / monitor control apparatus 60, Horizontal irradiation field forming electromagnet 71 as a beam scanning electromagnet, horizontal irradiation field forming electromagnet power supply 71a, vertical irradiation field forming electromagnet 72 as a beam scanning electromagnet, vertical irradiation field forming electromagnet power supply 72a, scanning irradiation control device 70, An interlock device 95 is provided.
- the irradiation device unit 40 has an irradiation port 90 installed in the treatment room 50.
- a vacuum duct 80 is installed in the irradiation port 90.
- a screen monitor 62 is installed in the vacuum duct 80.
- a position monitor 91 In the irradiation port 90, a position monitor 91, a beam block 92, a ridge filter 93, and a range shifter 94 are installed.
- the position monitor 91 is electrically connected to the interlock device 95 via the position monitor control device 91a.
- the screen monitors 61 and 62 are paired.
- the screen monitors 61 and 62 are inserted into the beam line only during adjustment of the beam axis, and are retracted from the beam line during treatment irradiation. Therefore, the screen monitors 61 and 62 are configured to be able to advance and retract with respect to the beam line by a drive mechanism (not shown).
- the screen monitors 61 and 62 are for measuring the beam position during the beam axis adjustment, and by making a pair, the beam trajectory (beam position and beam angle) can be obtained. Signals indicating the beam position and beam angle measured by the screen monitors 61 and 62 are output to the power supply / monitor control device 60.
- the horizontal correction electromagnet 51 and the vertical correction electromagnet 52 adjust the magnetic field based on the signal indicating the beam position and beam angle measured by the screen monitors 61 and 62, and adjust the beam axis of the affected part of the patient whose irradiation target is the target. This is an electromagnet for adjusting to an irradiation coordinate reference point (hereinafter referred to as isocenter) 96.
- the horizontal correction electromagnet 51 and the vertical correction electromagnet 52 adjust the current values of the horizontal correction electromagnet power supply 51a and the vertical correction electromagnet power supply 52a individually corresponding to the horizontal and vertical correction electromagnets 52a. Change.
- the irradiation field forming electromagnet is composed of a pair of a horizontal irradiation field forming electromagnet 71 and a vertical irradiation field forming electromagnet 72, and the horizontal irradiation field forming electromagnet 71 and the vertical irradiation field forming electromagnet 72 are screen monitors 61 and 62. Arranged between.
- the horizontal irradiation field forming electromagnet 71 and the vertical irradiation field forming electromagnet 72 are electromagnets for two-dimensional scanning of the beam in conformity with the shape of the affected part at the time of treatment irradiation.
- the position monitor 91 is for detecting a beam position scanned during treatment irradiation and monitoring whether or not there is a significant deviation from a preset position. When a significant deviation is recognized, an interlock signal is output to the interlock device 95 through the position monitor control device 91a.
- the ridge filter 93 is for adjusting the beam depth direction distribution in accordance with the interval between the irradiation slices.
- the ridge filter 93 is formed by forming bar-like rods in a substantially triangular shape from a metal such as aluminum and arranging them in a horizontal direction.
- the range shifter 94 is for changing the beam energy, that is, the depth of the stop position of the beam in the body.
- the range shifter 94 is made of a material such as acrylic and is composed of a plurality of thickness plates. The beam stop point can be changed by changing the combination of these multiple thickness plates.
- the beam block 92 is configured so that it can be inserted into and retracted from the beam line by the drive mechanism 97 in the same manner as the screen monitors 61 and 62.
- the beam block 92 is inserted into the beam line during the adjustment of the beam axis to stop the beam and prevent the beam from reaching the isocenter 96.
- an interlock signal is output to the interlock device 95, and the interlock device 95 sends an operation signal to the drive mechanism 97. Output.
- the drive mechanism 97 By operating the drive mechanism 97, the beam block 92 is inserted into the beam line. Further, the beam block 92 is retracted from the beam line by operating the drive mechanism 97 during treatment irradiation.
- the ion source in the beam generator 10 generates a beam.
- the beam injection system 11 accelerates the generated beam to an energy level that can be accelerated. This accelerated beam is incident on the circular accelerator 12.
- the beam incident on the circular accelerator 12 is repeatedly incident on a set number of times set in advance. After this round incidence is completed, the beam is further accelerated to the energy required for cancer treatment.
- the beam After the acceleration of the beam, the beam is taken out from the exit orbit by the beam extraction control unit 20 and transported to the irradiation device unit 40 by the beam transport unit 30.
- the irradiation device section 40 irradiates the isocenter 96 as an irradiation target and is used for cancer treatment.
- the screen monitor 61, 62 is inserted on the beam line by operating a drive mechanism (not shown), and the beam block 92 is inserted on the beam line by operating the drive mechanism 97.
- the pair of horizontal irradiation field forming electromagnets 71 and vertical irradiation field forming electromagnets 72 has a current pattern for demagnetization from the corresponding horizontal irradiation field forming electromagnet power supply 71a and vertical irradiation field forming electromagnet power supply 72a. Current is supplied to bring the respective magnetic fields to almost zero. In this state, the beam is introduced to the irradiation unit 40, and the beam axis position is detected by the screen monitors 61 and 62, respectively. This will be described with reference to FIGS.
- FIG. 3 is an explanatory diagram showing a pair of screen monitors in the embodiment.
- FIG. 4 is an explanatory diagram showing a beam trajectory adjustment method using the screen monitor of FIG.
- the external shape of the beam reflected on the fluorescent film in each of the screen monitors 61 and 62 is observed with a CCD camera (not shown), and the image is analyzed to determine the amount of deviation X 1 between the beam center and the monitor center. to calculate the X 2.
- the power correction / monitor control device 60 uses the deviation correction amounts X 1 , X 2 of the horizontal correction electromagnet power supply 51 a and the vertical correction electromagnet power supply 52 a.
- the current correction amount is obtained, and the corrected current value signal is output to the horizontal correction electromagnet power supply 51a and the vertical correction electromagnet power supply 52a.
- the threshold value is an amount of deviation of the beam axis allowed for performing the treatment.
- the horizontal correction electromagnet 51 and the vertical correction electromagnet 52 can adjust the beam axis to the isocenter 96 by changing the magnetic field.
- the screen monitor 62 on the downstream side with respect to the beam transport direction is disposed in the treatment room 50, so that a sufficient distance can be obtained between the two screen monitors 61 and 62. . Further, the downstream screen monitor 62 can be brought close to the isocenter 96.
- the distance between the two screen monitors 61 and 62 can be sufficiently set, the deviation of the beam axis can be confirmed accurately, and the accuracy of the beam trajectory is improved. be able to.
- downstream screen monitor 62 can be brought closer to the isocenter 96, the accuracy of the beam trajectory with respect to the isocenter 96 can be further improved.
- the vacuum region can be brought as close as possible to the vicinity of the isocenter 96, and the beam is not transported over a long distance in the atmosphere. Scattering can be suppressed. Thereby, an affected part can be irradiated with a thin beam at the time of treatment irradiation.
- a beam block 92 is installed in the irradiation port 90 in order to suppress beam leakage toward the affected part downstream in the beam transport direction.
- the beam block 92 is inserted on the beam line to shield the beam (retracted from the beam trajectory during normal treatment).
- the beam block 92 is designed to have an optimum thickness that shields the beam irradiated when adjusting the beam trajectory and does not affect the affected part on the downstream side with respect to the beam transport direction. For this reason, even if the position monitor 91 detects a beam misalignment during treatment irradiation, the beam trajectory can be corrected by the following procedure without retracting the patient from the irradiation position when the treatment is interrupted. .
- FIG. 5 is a flowchart showing a procedure for correcting the beam trajectory in the embodiment.
- the patient is positioned.
- step S1 beam irradiation is started (step S2).
- step S2 the beam is irradiated until the position monitor 91 detects a beam position shift.
- step S3 the process proceeds to step S3, and the interlock device 95 is operated. Then, the interlock device 95 outputs an interlock signal and interrupts beam irradiation (step S4).
- the screen monitor 61, 62 is inserted on the beam line by operating a drive mechanism (not shown), and the beam block 92 is inserted on the beam line by operating the drive mechanism 97 (step S5).
- the beam axis is adjusted in step S6.
- the beam is introduced to the irradiation unit 40 in the above-described state, and the beam axis position is detected by the respective screen monitors 61 and 62.
- a signal indicating the amount of beam deviation detected by the screen monitors 61 and 62 is output to the power supply / monitor control device 60.
- the power supply / monitor control device 60 obtains the current correction amounts of the horizontal correction electromagnet power supply 51a and the vertical correction electromagnet power supply 52a, and uses the corrected current value signals as the horizontal correction electromagnet power supply 51a and the vertical correction electromagnet power supply 52a. Output to and set. Thereby, the horizontal correction electromagnet 51 and the vertical correction electromagnet 52 adjust the beam axis by changing the magnetic field.
- step S7 when the adjustment of the beam axis is completed (step S7: Yes), the process proceeds to step S8.
- step S8 the drive mechanism (not shown) is operated again to retract the screen monitors 61 and 62 from the beam line, and the drive mechanism 97 is operated to retract the beam block 92 from the beam line to correct the beam trajectory. End and resume beam irradiation.
- a residual magnetic field may remain in the horizontal irradiation field forming electromagnet 71 and the vertical irradiation field forming electromagnet 72. Therefore, it is suitable to insert a step of demagnetizing the horizontal irradiation field forming electromagnet 71 and the vertical irradiation field forming electromagnet 72 between the steps S5 and S6.
- a current pattern defined for demagnetization can be flowed from the horizontal irradiation field forming electromagnet power supply 71a and the vertical irradiation field forming electromagnet power supply 72a.
- the beam can be shielded by the beam block 92 to avoid exposure of the patient, so that the patient does not have to get off the treatment table. Therefore, irradiation of the beam for cancer treatment can be resumed in a short time, and the burden on the patient can be greatly reduced.
- the beam block 92 is arranged on the downstream side of the position monitor 91 so that the beam can be monitored by the position monitor 91 even when the beam is shielded. Can be confirmed (cross-check) by both the position monitor 91 and the downstream screen monitor 62. For this reason, the reliability of a beam position can be improved.
- the range shifter 94 is disposed on the downstream side of the beam block 92, and the range shifter 94 is fully inserted when the beam is blocked, thereby further improving the beam blocking effect.
- the screen monitor 62 disposed in the treatment room 50 is stored in the vacuum duct 80, and it is possible to secure a vacuum just upstream of the position monitor 91.
- the influence of scattering can be reduced, and the beam quality can be ensured.
- the adjustment accuracy of the beam trajectory, the operability until resumption after the beam interruption, and the quality of the treatment beam. can be improved.
- the beam block 92 when the position monitor 91 detects a beam misalignment during treatment irradiation, the beam block 92 is used to correct the beam trajectory without retracting the patient from the irradiation position when the treatment is interrupted. The beam block 92 is not required if the patient is withdrawn from the irradiation position.
- SYMBOLS 10 ... Beam generation part, 11 ... Beam injection system, 12 ... Circular accelerator, 20 ... Beam extraction control part, 30 ... Beam transport part, 40 ... Irradiation apparatus part, 50 ... Treatment room, 51 ... Horizontal correction electromagnet, 51a ... Horizontal correction electromagnet power supply, 52 ... Vertical correction electromagnet, 52a ... Vertical correction electromagnet power supply, 60 ... Power supply / monitor control device, 61 ... Screen monitor, 62 ... Screen monitor, 70 ... Scanning irradiation control device, 71 ... Horizontal use Irradiation field forming electromagnet (beam scanning electromagnet), 71a ...
- Horizontal irradiation field forming electromagnet power supply 72 ... Vertical irradiation field forming electromagnet (beam scanning electromagnet), 72a ... Vertical irradiation field forming electromagnet power supply, 80 ... Vacuum duct, 90 ... Irradiation port, 91 ... Position monitor, 91a ... Position monitor controller, 92 ... Beam block, 93 ... Ridge filter, 94 ... Range shift , 95 ... interlocking device, 96 ... isocenter (irradiation target), 97 ... drive mechanism
Landscapes
- Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Biomedical Technology (AREA)
- Pathology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Radiology & Medical Imaging (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Physics & Mathematics (AREA)
- Spectroscopy & Molecular Physics (AREA)
- General Engineering & Computer Science (AREA)
- High Energy & Nuclear Physics (AREA)
- Plasma & Fusion (AREA)
- Optics & Photonics (AREA)
- Radiation-Therapy Devices (AREA)
- Measurement Of Radiation (AREA)
Abstract
Description
本発明のいくつかの実施形態を説明したが、これらの実施形態は、例として提示したものであり、発明の範囲を限定することは意図していない。これら実施形態は、その他の様々な形態で実施されることが可能であり、発明の要旨を逸脱しない範囲で、種々の省略、置き換え、変更、組み合わせを行うことができる。これら実施形態やその変形は、発明の範囲や要旨に含まれると同様に、特許請求の範囲に記載された発明とその均等の範囲に含まれるものである。
Claims (12)
- ビーム輸送部から輸送された粒子線ビームの位置ずれを検出する位置モニタと、
前記粒子線ビームの軸の位置及び角度を測定する対をなすスクリーンモニタと、
前記スクリーンモニタにより測定された前記粒子線ビームの軸の位置及び角度を示す信号に基づいて磁場を調整して前記粒子線ビームの軸を調整する補正電磁石と、
前記粒子線ビームを照射対象に照射するビーム走査電磁石と、を備え、
前記対をなすスクリーンモニタの一方を治療室外に設置し、かつ前記スクリーンモニタの他方を前記治療室内に設置したことを特徴とする粒子線ビーム調整装置。 - 前記粒子線ビームの軸の調整時に、前記治療室内の照射対象に達する前記粒子線ビームを停止させるビームブロックを有することを特徴とする請求項1に記載の粒子線ビーム調整装置。
- 前記ビームブロックは、前記治療室内に設置した前記スクリーンモニタの前記粒子線ビームの輸送方向下流側に設置されていることを特徴とする請求項2に記載の粒子線ビーム調整装置。
- 前記ビームブロックの前記粒子線ビームの輸送方向下流側に、前記粒子線ビームの停止点を変化させるレンジシフタが設置されていることを特徴とする請求項2又は3に記載の粒子線ビーム調整装置。
- 前記対をなすスクリーンモニタは、真空ダクト内に収納されていることを特徴とする請求項1ないし4のいずれか一項に記載の粒子線ビーム調整装置。
- 前記対をなすスクリーンモニタ及び前記ビームブロックは、前記粒子線ビームが輸送されるビームラインに対して挿入及び退避可能に構成したことを特徴とする請求項1ないし5のいずれか一項に記載の粒子線ビーム調整装置。
- ビーム輸送部から輸送された粒子線ビームの位置ずれを検出する位置モニタと、
前記粒子線ビームを照射対象に照射するビーム走査電磁石と、
前記粒子線ビームの軸の調整時に、治療室内の照射対象に達する前記粒子線ビームを停止させるビームブロックを備え、
前記ビームブロックは、前記治療室内に設置されていることを特徴とする粒子線ビーム調整装置。 - 前記ビームブロックの前記粒子線ビームの輸送方向上流側に、前記位置モニタが設置されていることを特徴とする請求項7に記載の粒子線ビーム調整装置。
- 前記ビームブロックの前記粒子線ビームの輸送方向下流側に、前記粒子線ビームの停止点を変化させるレンジシフタが設置されていることを特徴とする請求項7に記載の粒子線ビーム調整装置。
- ビーム輸送部から輸送された粒子線ビームの軸のずれを検出するビーム位置ずれ検出工程と、
前記粒子線ビームの軸の位置及び角度を、治療室外に設置された一方のスクリーンモニタと前記治療室内に設置された他方のスクリーンモニタとで測定する測定工程と、
前記測定工程で測定された前記粒子線ビームの軸の位置及び角度に基づいて磁場を調整して前記粒子線ビームの軸を調整するビーム軸調整工程と、
を有することを特徴とする粒子線ビーム調整方法。 - 前記粒子線ビームを走査するビーム走査電磁石を消磁するビーム走査電磁石消磁工程をさらに有することを特徴とする請求項10に記載の粒子線ビーム調整方法。
- 粒子線ビームを生成するビーム生成部と、
前記粒子線ビームの出射を制御するビーム出射制御装置と、
前記粒子線ビームを治療室の照射対象まで輸送するビーム輸送部と、
前記ビーム輸送部から輸送された粒子線ビームの位置ずれを検出する位置モニタと、
前記粒子線ビームの軸の位置及び角度を測定する対をなすスクリーンモニタと、
前記スクリーンモニタにより測定された前記粒子線ビームの軸の位置及び角度を示す信号に基づいて磁場を調整して前記粒子線ビームの軸を調整する補正電磁石と、
前記粒子線ビームを照射対象に照射するビーム走査電磁石と、を備え、
前記対をなすスクリーンモニタの一方を前記治療室外に設置し、かつ前記スクリーンモニタの他方を前記治療室内に設置したことを特徴とする粒子線照射装置。
Priority Applications (4)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
PCT/JP2014/006068 WO2016088155A1 (ja) | 2014-12-04 | 2014-12-04 | 粒子線ビーム調整装置及び方法、粒子線治療装置 |
JP2016562090A JP6462718B2 (ja) | 2014-12-04 | 2014-12-04 | 粒子線ビーム調整装置及び方法、粒子線治療装置 |
CN201480083763.5A CN107004453B (zh) | 2014-12-04 | 2014-12-04 | 粒子线束调整装置以及方法、粒子线治疗装置 |
US15/532,860 US10434337B2 (en) | 2014-12-04 | 2014-12-04 | Particle beam adjustment device, particle beam adjustment method, and particle beam therapeutic device |
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
PCT/JP2014/006068 WO2016088155A1 (ja) | 2014-12-04 | 2014-12-04 | 粒子線ビーム調整装置及び方法、粒子線治療装置 |
Publications (1)
Publication Number | Publication Date |
---|---|
WO2016088155A1 true WO2016088155A1 (ja) | 2016-06-09 |
Family
ID=56091137
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
PCT/JP2014/006068 WO2016088155A1 (ja) | 2014-12-04 | 2014-12-04 | 粒子線ビーム調整装置及び方法、粒子線治療装置 |
Country Status (4)
Country | Link |
---|---|
US (1) | US10434337B2 (ja) |
JP (1) | JP6462718B2 (ja) |
CN (1) | CN107004453B (ja) |
WO (1) | WO2016088155A1 (ja) |
Cited By (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JP2020010887A (ja) * | 2018-07-19 | 2020-01-23 | 住友重機械工業株式会社 | 荷電粒子線治療装置 |
US10661101B2 (en) * | 2015-07-01 | 2020-05-26 | Hitachi, Ltd. | Dose distribution calculation device, particle beam therapy system, and dose distribution calculation method |
Families Citing this family (5)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
EP3338857B1 (en) * | 2016-12-21 | 2021-08-11 | RaySearch Laboratories AB | System and method for determining a treatment plan for active ion beam treatment |
CN107648749B (zh) * | 2017-09-28 | 2020-02-07 | 上海联影医疗科技有限公司 | 放射治疗系统及其束流控制装置和束流准直方法 |
CN110267709B (zh) * | 2018-01-12 | 2021-05-18 | 新瑞阳光粒子医疗装备(无锡)有限公司 | 束流控制方法、装置、质子放疗系统及存储介质 |
JP2020099569A (ja) * | 2018-12-25 | 2020-07-02 | 株式会社日立製作所 | 粒子線治療システムおよび線量分布評価システム、ならびに粒子線治療システムの作動方法 |
CN109637692B (zh) * | 2019-01-23 | 2023-12-19 | 深圳铭杰医疗科技有限公司 | 适用于带电粒子束的轨迹矫正器 |
Citations (5)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JP2002058750A (ja) * | 2000-08-21 | 2002-02-26 | Toshiba Corp | 荷電ビーム照射方法および装置、ならびにコンピュータが読取り可能な記憶媒体 |
JP2003282300A (ja) * | 2002-03-26 | 2003-10-03 | Hitachi Ltd | 粒子線治療システム |
JP2010253240A (ja) * | 2009-10-13 | 2010-11-11 | Mitsubishi Electric Corp | 粒子線治療装置 |
JP2012064403A (ja) * | 2010-09-15 | 2012-03-29 | Hitachi Ltd | 荷電粒子ビーム照射装置 |
JP2012205837A (ja) * | 2011-03-30 | 2012-10-25 | Sumitomo Heavy Ind Ltd | 荷電粒子線照射装置及び荷電粒子線照射装置の照射位置検出方法 |
Family Cites Families (28)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US5017789A (en) * | 1989-03-31 | 1991-05-21 | Loma Linda University Medical Center | Raster scan control system for a charged-particle beam |
CN1299782C (zh) * | 2001-07-24 | 2007-02-14 | 住友重机械工业株式会社 | 电荷粒子射线的辐射剂量分布调整机构和辐射装置 |
JP3859605B2 (ja) * | 2003-03-07 | 2006-12-20 | 株式会社日立製作所 | 粒子線治療システム及び粒子線出射方法 |
JP4257741B2 (ja) * | 2004-04-19 | 2009-04-22 | 三菱電機株式会社 | 荷電粒子ビーム加速器、荷電粒子ビーム加速器を用いた粒子線照射医療システムおよび、粒子線照射医療システムの運転方法 |
US7385203B2 (en) * | 2005-06-07 | 2008-06-10 | Hitachi, Ltd. | Charged particle beam extraction system and method |
US7263170B2 (en) * | 2005-09-30 | 2007-08-28 | Pellegrino Anthony J | Radiation therapy system featuring rotatable filter assembly |
US7402823B2 (en) * | 2006-06-05 | 2008-07-22 | Varian Medical Systems Technologies, Inc. | Particle beam system including exchangeable particle beam nozzle |
JP4378396B2 (ja) * | 2007-06-22 | 2009-12-02 | 株式会社日立製作所 | 粒子線照射システム |
JP5074915B2 (ja) * | 2007-12-21 | 2012-11-14 | 株式会社日立製作所 | 荷電粒子ビーム照射システム |
JP5477736B2 (ja) * | 2009-03-25 | 2014-04-23 | 独立行政法人放射線医学総合研究所 | 粒子線照射装置 |
WO2010122662A1 (ja) * | 2009-04-24 | 2010-10-28 | 三菱電機株式会社 | 粒子線治療装置 |
JP2010253000A (ja) * | 2009-04-24 | 2010-11-11 | Hitachi Ltd | 放射線照射システム |
WO2010140236A1 (ja) * | 2009-06-03 | 2010-12-09 | 三菱電機株式会社 | 粒子線照射装置 |
JP5133319B2 (ja) * | 2009-09-30 | 2013-01-30 | 株式会社日立製作所 | 粒子線照射システムおよびその制御方法 |
JP2011120810A (ja) * | 2009-12-14 | 2011-06-23 | Toshiba Corp | 粒子線ビーム照射装置 |
JP5463509B2 (ja) | 2010-02-10 | 2014-04-09 | 株式会社東芝 | 粒子線ビーム照射装置及びその制御方法 |
EP2653191B1 (en) * | 2011-02-17 | 2015-08-19 | Mitsubishi Electric Corporation | Particle beam therapy system |
JP5717859B2 (ja) * | 2011-08-23 | 2015-05-13 | 三菱電機株式会社 | ビームデータ処理装置及び粒子線治療装置 |
US9199094B2 (en) * | 2011-08-31 | 2015-12-01 | Hitachi, Ltd. | Charged particle beam irradiation system and operating method of charged particle beam irradiation system |
JP5816518B2 (ja) * | 2011-10-31 | 2015-11-18 | 株式会社日立製作所 | 粒子線照射システム及びビーム補正方法 |
WO2013069090A1 (ja) * | 2011-11-08 | 2013-05-16 | 三菱電機株式会社 | 粒子線治療システムおよびそのビーム位置補正方法 |
JP5791546B2 (ja) * | 2012-02-29 | 2015-10-07 | 株式会社日立製作所 | 放射線計測装置の較正方法及び粒子線治療装置 |
JP5668000B2 (ja) * | 2012-03-02 | 2015-02-12 | 株式会社日立製作所 | ビームモニタシステム及び粒子線照射システム |
JP5868249B2 (ja) * | 2012-04-10 | 2016-02-24 | 株式会社日立製作所 | 粒子線治療システム |
US9078335B2 (en) * | 2012-05-24 | 2015-07-07 | Mitsubishi Electric Corporation | Charged particle beam transport system and particle beam therapy system |
US9165744B2 (en) * | 2012-10-24 | 2015-10-20 | Varian Semiconductor Equipment Associates, Inc. | Apparatus for treating ion beam |
JP6066478B2 (ja) * | 2013-01-29 | 2017-01-25 | 株式会社日立製作所 | 粒子線治療システム |
JP6692115B2 (ja) * | 2014-02-25 | 2020-05-13 | 株式会社日立製作所 | ビーム位置監視装置及び荷電粒子ビーム照射システム |
-
2014
- 2014-12-04 US US15/532,860 patent/US10434337B2/en not_active Expired - Fee Related
- 2014-12-04 WO PCT/JP2014/006068 patent/WO2016088155A1/ja active Application Filing
- 2014-12-04 CN CN201480083763.5A patent/CN107004453B/zh not_active Expired - Fee Related
- 2014-12-04 JP JP2016562090A patent/JP6462718B2/ja not_active Expired - Fee Related
Patent Citations (5)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JP2002058750A (ja) * | 2000-08-21 | 2002-02-26 | Toshiba Corp | 荷電ビーム照射方法および装置、ならびにコンピュータが読取り可能な記憶媒体 |
JP2003282300A (ja) * | 2002-03-26 | 2003-10-03 | Hitachi Ltd | 粒子線治療システム |
JP2010253240A (ja) * | 2009-10-13 | 2010-11-11 | Mitsubishi Electric Corp | 粒子線治療装置 |
JP2012064403A (ja) * | 2010-09-15 | 2012-03-29 | Hitachi Ltd | 荷電粒子ビーム照射装置 |
JP2012205837A (ja) * | 2011-03-30 | 2012-10-25 | Sumitomo Heavy Ind Ltd | 荷電粒子線照射装置及び荷電粒子線照射装置の照射位置検出方法 |
Non-Patent Citations (3)
Title |
---|
"Kengakusha-yo] Carbon Ion Radiotherapy HIMAC', National Institute of Radiological Sciences", 8 May 2014 (2014-05-08), pages 3, Retrieved from the Internet <URL:http://www.nirs.go.jp/publication/pamphlets/index.shtml> [retrieved on 20150204] * |
"Sekai Saikosoku 3 Jigen Scanning Shoshaho o Mochiita Chiryo o Kaishi -Nippon Hatsu no Jisedaigata Juryushisen Gan Chiryo, Aratana Tenkai e", NATIONAL INSTITUTE OF RADIOLOGICAL SCIENCES, 22 June 2011 (2011-06-22), Retrieved from the Internet <URL:http://www.nirs.go.jp/information/press/2011/06_22.shtml> [retrieved on 20150204] * |
HIKARU SODA ET AL.: "DEVELOPMENT OF SCANNING IRRADIATION IN GUNMA UNIVERSITY HEAVY ION MEDICAL CENTER", PROCEEDINGS OF THE LLTH ANNUAL MEETING OF PARTICLE ACCELERATOR SOCIETY OF JAPAN, 9 August 2014 (2014-08-09), pages 890 * |
Cited By (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US10661101B2 (en) * | 2015-07-01 | 2020-05-26 | Hitachi, Ltd. | Dose distribution calculation device, particle beam therapy system, and dose distribution calculation method |
JP2020010887A (ja) * | 2018-07-19 | 2020-01-23 | 住友重機械工業株式会社 | 荷電粒子線治療装置 |
JP7233179B2 (ja) | 2018-07-19 | 2023-03-06 | 住友重機械工業株式会社 | 荷電粒子線治療装置 |
Also Published As
Publication number | Publication date |
---|---|
CN107004453B (zh) | 2019-07-19 |
US10434337B2 (en) | 2019-10-08 |
JP6462718B2 (ja) | 2019-01-30 |
CN107004453A (zh) | 2017-08-01 |
US20170368371A1 (en) | 2017-12-28 |
JPWO2016088155A1 (ja) | 2017-11-02 |
Similar Documents
Publication | Publication Date | Title |
---|---|---|
JP6462718B2 (ja) | 粒子線ビーム調整装置及び方法、粒子線治療装置 | |
JP5496414B2 (ja) | 粒子線治療装置 | |
JP7090451B2 (ja) | 荷電粒子線治療装置 | |
KR101411055B1 (ko) | 입자선 조사 시스템 및 하전 입자 빔의 보정 방법 | |
US20150238780A1 (en) | Beam position monitoring apparatus and charged particle beam irradiation system | |
TW201433330A (zh) | 粒子射線治療裝置 | |
JP2009039219A (ja) | 荷電粒子ビーム照射システム及び荷電粒子ビーム照射方法 | |
JP2015208598A (ja) | 粒子線治療システムおよびプログラムならびに粒子線治療システムの制御方法 | |
US20150126798A1 (en) | Control device for scanning electromagnet and particle beam therapy apparatus | |
US10485994B2 (en) | Charged particle beam treatment apparatus | |
US20210031056A1 (en) | Charged particle beam treatment apparatus | |
US9630027B2 (en) | Beam transport system and particle beam therapy system | |
JP5320185B2 (ja) | 粒子線照射制御装置 | |
JP2015179586A (ja) | 荷電粒子線治療装置 | |
JP5350307B2 (ja) | 粒子線治療システム | |
JP7430044B2 (ja) | 放射線治療装置 | |
TWI515026B (zh) | 中隔電磁石及粒子束治療裝置 | |
TWI681794B (zh) | 帶電粒子束治療裝置 | |
JPWO2017199385A1 (ja) | 粒子線治療装置用のビームモニタ及び粒子線治療装置 | |
JP6494808B2 (ja) | 粒子線治療装置 | |
JP6815231B2 (ja) | 荷電粒子線治療装置 | |
JP6215086B2 (ja) | 荷電粒子線治療装置及び荷電粒子線治療装置の制御方法 | |
JP2020010887A (ja) | 荷電粒子線治療装置 | |
JP2019150254A (ja) | 荷電粒子線治療装置及び荷電粒子線治療装置の作動方法 | |
JP2011234960A (ja) | 偏向電磁石調整装置、粒子線照射装置、粒子線治療装置及び偏向電磁石調整方法 |
Legal Events
Date | Code | Title | Description |
---|---|---|---|
121 | Ep: the epo has been informed by wipo that ep was designated in this application |
Ref document number: 14907609 Country of ref document: EP Kind code of ref document: A1 |
|
ENP | Entry into the national phase |
Ref document number: 2016562090 Country of ref document: JP Kind code of ref document: A |
|
WWE | Wipo information: entry into national phase |
Ref document number: 15532860 Country of ref document: US |
|
NENP | Non-entry into the national phase |
Ref country code: DE |
|
122 | Ep: pct application non-entry in european phase |
Ref document number: 14907609 Country of ref document: EP Kind code of ref document: A1 |