WO2015053576A1 - Method for preparation of 3-alkylthio-2-bromopyridine - Google Patents

Method for preparation of 3-alkylthio-2-bromopyridine Download PDF

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Publication number
WO2015053576A1
WO2015053576A1 PCT/KR2014/009508 KR2014009508W WO2015053576A1 WO 2015053576 A1 WO2015053576 A1 WO 2015053576A1 KR 2014009508 W KR2014009508 W KR 2014009508W WO 2015053576 A1 WO2015053576 A1 WO 2015053576A1
Authority
WO
WIPO (PCT)
Prior art keywords
dienenitrile
penta
formula
alkyl
phenyl
Prior art date
Application number
PCT/KR2014/009508
Other languages
English (en)
French (fr)
Inventor
Sei Chang Ahn
Sook Hee Kim
Sadaiah KADIVENDI
Seo Yeon Lee
Ki Dae Kim
In Ae RYU
Original Assignee
Lg Life Sciences Ltd.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Lg Life Sciences Ltd. filed Critical Lg Life Sciences Ltd.
Priority to JP2016521955A priority Critical patent/JP6257115B2/ja
Priority to CN201480054868.8A priority patent/CN105636938B/zh
Publication of WO2015053576A1 publication Critical patent/WO2015053576A1/en

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Classifications

    • A—HUMAN NECESSITIES
    • A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
    • A01N47/00—Biocides, pest repellants or attractants, or plant growth regulators containing organic compounds containing a carbon atom not being member of a ring and having no bond to a carbon or hydrogen atom, e.g. derivatives of carbonic acid
    • A01N47/08—Biocides, pest repellants or attractants, or plant growth regulators containing organic compounds containing a carbon atom not being member of a ring and having no bond to a carbon or hydrogen atom, e.g. derivatives of carbonic acid the carbon atom having one or more single bonds to nitrogen atoms
    • A01N47/28—Ureas or thioureas containing the groups >N—CO—N< or >N—CS—N<
    • A01N47/36—Ureas or thioureas containing the groups >N—CO—N< or >N—CS—N< containing the group >N—CO—N< directly attached to at least one heterocyclic ring; Thio analogues thereof
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C323/00—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups
    • C07C323/23—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups containing thio groups and nitrogen atoms, not being part of nitro or nitroso groups, bound to the same carbon skeleton
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C319/00—Preparation of thiols, sulfides, hydropolysulfides or polysulfides
    • C07C319/14—Preparation of thiols, sulfides, hydropolysulfides or polysulfides of sulfides
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C323/00—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups
    • C07C323/23—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups containing thio groups and nitrogen atoms, not being part of nitro or nitroso groups, bound to the same carbon skeleton
    • C07C323/31—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups containing thio groups and nitrogen atoms, not being part of nitro or nitroso groups, bound to the same carbon skeleton having the sulfur atom of at least one of the thio groups bound to a carbon atom of a six-membered aromatic ring of the carbon skeleton
    • C07C323/32—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups containing thio groups and nitrogen atoms, not being part of nitro or nitroso groups, bound to the same carbon skeleton having the sulfur atom of at least one of the thio groups bound to a carbon atom of a six-membered aromatic ring of the carbon skeleton having at least one of the nitrogen atoms bound to an acyclic carbon atom of the carbon skeleton
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C323/00—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups
    • C07C323/50—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups containing thio groups and carboxyl groups bound to the same carbon skeleton
    • C07C323/51—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups containing thio groups and carboxyl groups bound to the same carbon skeleton having the sulfur atoms of the thio groups bound to acyclic carbon atoms of the carbon skeleton
    • C07C323/60—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups containing thio groups and carboxyl groups bound to the same carbon skeleton having the sulfur atoms of the thio groups bound to acyclic carbon atoms of the carbon skeleton with the carbon atom of at least one of the carboxyl groups bound to nitrogen atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
    • C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
    • C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D213/24—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with substituted hydrocarbon radicals attached to ring carbon atoms
    • C07D213/28—Radicals substituted by singly-bound oxygen or sulphur atoms
    • C07D213/32—Sulfur atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D295/00—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
    • C07D295/04—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms
    • C07D295/14—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
    • C07D295/145—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals with the ring nitrogen atoms and the carbon atoms with three bonds to hetero atoms attached to the same carbon chain, which is not interrupted by carbocyclic rings
PCT/KR2014/009508 2013-10-11 2014-10-10 Method for preparation of 3-alkylthio-2-bromopyridine WO2015053576A1 (en)

Priority Applications (2)

Application Number Priority Date Filing Date Title
JP2016521955A JP6257115B2 (ja) 2013-10-11 2014-10-10 ３−アルキルチオ−２−ブロモピリジンの製造方法
CN201480054868.8A CN105636938B (zh) 2013-10-11 2014-10-10 制备3-烷硫基-2-溴吡啶的方法

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
KR10-2013-0121556 2013-10-11
KR20130121556 2013-10-11

Publications (1)

Publication Number Publication Date
WO2015053576A1 true WO2015053576A1 (en) 2015-04-16

Family

ID=52813338

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/KR2014/009508 WO2015053576A1 (en) 2013-10-11 2014-10-10 Method for preparation of 3-alkylthio-2-bromopyridine

Country Status (4)

Country Link
JP (1) JP6257115B2 (ko)
KR (1) KR101603324B1 (ko)
CN (1) CN105636938B (ko)
WO (1) WO2015053576A1 (ko)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN106866514B (zh) * 2017-02-10 2019-05-28 山东师范大学 一种水相法合成2-卤代-3-取代烃基磺酰基吡啶及其中间体的方法
CN106866515B (zh) * 2017-02-10 2019-05-28 山东师范大学 一种磺酰基吡啶衍生物及其合成方法

Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5278318A (en) * 1989-09-19 1994-01-11 Allergan, Inc. Process of synthesizing acetylenes disubstituted with a phenyl group and a 2-substituted chromanyl, thiochromanyl or 1,2,3,4-tetrahydroquinolinyl group
KR20030085788A (ko) * 2002-05-02 2003-11-07 주식회사 엘지생명과학 피리딘 유도체, 그의 제조방법, 및 제초제 중간체로서의용도
US20040209921A1 (en) * 2003-04-11 2004-10-21 Gary Bridger CXCR4 chemokine receptor binding comounds

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Publication number Priority date Publication date Assignee Title
US4234590A (en) * 1979-02-05 1980-11-18 Merck & Co., Inc. Thiosubstituted pyridines
DE3322281A1 (de) * 1983-06-16 1984-12-20 Schering AG, 1000 Berlin und 4709 Bergkamen (alpha)-alkylthiozimtsaeurenitrile zur bekaempfung von schadorganismen
FR2621038B1 (fr) * 1987-09-28 1989-12-29 Rhone Poulenc Sante Derives d'alcadienes, leurs preparations, les medicaments les contenant et produits intermediaires
DE3840954A1 (de) * 1988-12-05 1990-06-07 Shell Int Research Herstellung von 2-chlornicotinsaeureestern
FR2657543B1 (fr) * 1990-01-26 1992-12-18 Biocom Sa Dispositif modulaire pour le recueil, l'incubation, la filtration d'echantillons multiples.
EP0462639A1 (en) * 1990-06-05 1991-12-27 Shell Internationale Researchmaatschappij B.V. Preparation of 2-chloropyridine derivatives
JP3880883B2 (ja) * 2002-05-20 2007-02-14 エルジー ケム インヴェストメント リミティッド ピリジン誘導体、その製造方法、及び除草剤中間体としての用途
GB0614154D0 (en) * 2006-07-17 2006-08-23 Syngenta Participations Ag Novel Pyriazine Derivatives
JP2011195578A (ja) * 2010-02-25 2011-10-06 Sumitomo Chemical Co Ltd エステル化合物及びその用途
EP2547314A2 (en) * 2010-03-15 2013-01-23 L'Oréal Composition comprising a dibenzoylmethane screening agent and a merocyanine dicyano or cyanoacetate derivative; method for the photostabilization of the dibenzoylmethane screening agent
KR101493488B1 (ko) * 2012-07-13 2015-02-16 주식회사 엘지생명과학 신규의 피리딘 유도체 및 이를 이용한 설포닐우레아 제초제의 제조 중간체 화합물의 제조방법

Patent Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5278318A (en) * 1989-09-19 1994-01-11 Allergan, Inc. Process of synthesizing acetylenes disubstituted with a phenyl group and a 2-substituted chromanyl, thiochromanyl or 1,2,3,4-tetrahydroquinolinyl group
KR20030085788A (ko) * 2002-05-02 2003-11-07 주식회사 엘지생명과학 피리딘 유도체, 그의 제조방법, 및 제초제 중간체로서의용도
US20040209921A1 (en) * 2003-04-11 2004-10-21 Gary Bridger CXCR4 chemokine receptor binding comounds

Non-Patent Citations (1)

* Cited by examiner, † Cited by third party
Title
MIEKO ARISAWA ET AL.: "Addition Reaction of Dialkyl Disulfides to Terminal Alkynes Catalyzed by a Rhodium Complex and Trifluoromethanesulfonic Acid", ORGANIC LETTERS, vol. 3, no. 5, 2001, pages 763 - 764 *

Also Published As

Publication number Publication date
KR20150042736A (ko) 2015-04-21
KR101603324B1 (ko) 2016-03-14
JP2016538251A (ja) 2016-12-08
CN105636938B (zh) 2018-09-07
CN105636938A (zh) 2016-06-01
JP6257115B2 (ja) 2018-01-10

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